Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_049859234.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049831263.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049827013.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049854695.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049852773.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049838572.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049851719.1	27	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-72086;Reactome: R-HSA-191859;Reactome: R-HSA-167200;Reactome: R-HSA-72187;Reactome: R-HSA-159227;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-159236;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-975957;Reactome: R-HSA-8851708	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Capping";"snRNP Assembly";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA 3'-end processing";"Transport of the SLBP independent Mature mRNA";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM"
XP_049836158.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049853296.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_049848273.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049839877.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049857122.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049840259.1	12	MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)"
XP_049850185.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049864406.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_049852263.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_049840301.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049863637.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049831490.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049848960.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_049837064.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049851409.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049862803.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049836663.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049852994.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049849331.1	11	MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517	"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane"
XP_049837090.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049847182.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049830790.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049864585.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049826997.1	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049843998.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_049864396.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049858513.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049853840.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049830009.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049848648.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049826949.1	7	Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690	"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events"
XP_049846412.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_049848900.1	3	MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_049833258.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049846104.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049838364.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049846310.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049838370.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049840187.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049854482.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049857397.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049855687.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation"
XP_049851477.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_049864553.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049859385.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins"
XP_049848544.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049860683.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049855873.1	5	MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4	"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_049863367.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049847886.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049857937.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049861523.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049850622.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3232142	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins"
XP_049831751.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049853737.1	1	Reactome: R-HSA-8856825	"Cargo recognition for clathrin-mediated endocytosis"
XP_049847693.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049851644.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy"
XP_049838712.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049828311.1	6	KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_049832905.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827302.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049841730.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049847899.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049839242.1	3	MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661	"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis"
XP_049850927.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049838902.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049857836.1	12	KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7294;MetaCyc: PWY-5749;MetaCyc: PWY-7854;MetaCyc: PWY-5744;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7295;KEGG: 00660+4.1.3.25	"Pyruvate metabolism";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"D-xylose degradation IV";"Itaconate degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"L-arabinose degradation IV";"C5-Branched dibasic acid metabolism"
XP_049835012.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049851509.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_049860323.1	12	Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613	"Biotin transport and metabolism";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_049846717.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049861597.1	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_049861380.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049855894.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049850969.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049851042.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049845303.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049838588.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049854497.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_049855300.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049828376.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049830492.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-419037	"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Signaling by PDGF";"Extracellular matrix organization";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Collagen chain trimerization";"NCAM1 interactions"
XP_049863065.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_049847206.1	11	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"p38MAPK events";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_049844512.1	24	Reactome: R-HSA-8853659;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-9010642;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5687128;Reactome: R-HSA-442720;Reactome: R-HSA-111931;Reactome: R-HSA-983231;Reactome: R-HSA-163560;Reactome: R-HSA-381676;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-163358;Reactome: R-HSA-392517;Reactome: R-HSA-432040;Reactome: R-HSA-5621575;Reactome: R-HSA-5610780;Reactome: R-HSA-164378;Reactome: R-HSA-8963896;Reactome: R-HSA-180024	"RET signaling";"Hedgehog 'off' state";"PKA activation";"ROBO receptors bind AKAP5";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA-mediated phosphorylation of CREB";"Factors involved in megakaryocyte development and platelet production";"Triglyceride catabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Rap1 signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"CD209 (DC-SIGN) signaling";"Degradation of GLI1 by the proteasome";"PKA activation in glucagon signalling";"HDL assembly";"DARPP-32 events"
XP_049850167.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049864245.1	12	KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5132	"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis"
XP_049829916.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049839986.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049858322.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_049844003.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847	"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones"
XP_049833831.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049830339.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049853508.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049856921.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049853733.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049859452.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049837758.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049863270.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049861724.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049834693.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049839240.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049851700.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049863085.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049846044.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049862523.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049846878.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_049844532.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25	"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch and sucrose metabolism"
XP_049844352.1	7	MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;Reactome: R-HSA-69205	"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription"
XP_049860489.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049827749.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049854658.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049844920.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_049837872.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049849010.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049858161.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049857103.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049831165.1	10	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049861614.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049861991.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049840396.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4	"Ether lipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049842658.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049838549.1	10	Reactome: R-HSA-5686938;Reactome: R-HSA-168188;Reactome: R-HSA-6798695;Reactome: R-HSA-5603041;Reactome: R-HSA-166058;Reactome: R-HSA-1461957;Reactome: R-HSA-168179;Reactome: R-HSA-5602498;Reactome: R-HSA-1236974;Reactome: R-HSA-9637628	"Regulation of TLR by endogenous ligand";"Toll Like Receptor TLR6:TLR2 Cascade";"Neutrophil degranulation";"IRAK4 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Beta defensins";"Toll Like Receptor TLR1:TLR2 Cascade";"MyD88 deficiency (TLR2/4)";"ER-Phagosome pathway";"Modulation by Mtb of host immune system"
XP_049863926.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049837817.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049827774.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress"
XP_049844618.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049835412.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049837105.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049861238.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049856758.1	18	KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049846281.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049845310.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049838637.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049857593.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Propanoate metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid degradation"
XP_049850687.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049837865.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049848873.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049834020.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_049830217.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049848260.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049861601.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049837766.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049829861.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049843952.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049840191.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049831763.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049833019.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049836179.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_049831168.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049838905.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
YP_010417147.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049851953.1	6	KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_049848593.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_049848973.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049862073.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844953.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049861169.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049859727.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_049860605.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049859236.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049862649.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049844875.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049830944.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049854247.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049838909.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049831760.1	8	MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_049853208.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049827033.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049845734.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049859197.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049855409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049859159.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049840629.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049859728.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_049831108.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049833469.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049856226.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049857546.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049853514.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049829542.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049850345.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049829698.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (z) signalling events"
XP_049842644.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402	"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex"
XP_049841854.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049853595.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049845009.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049850982.1	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
XP_049854601.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049838429.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049844722.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049835271.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049845907.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049844547.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049854472.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049864094.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle"
XP_049830756.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_049860516.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049857965.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049853058.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049864515.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049848941.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation"
XP_049856864.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049864830.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049845635.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049840263.1	12	MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway"
XP_049848010.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049830296.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049842826.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049830803.1	9	MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis"
XP_049836954.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049856489.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049836982.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_049852308.1	4	KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism"
XP_049853240.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049850856.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049864370.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049828430.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_049852014.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_049859886.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049847956.1	11	Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695	"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049862451.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049848693.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049863702.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049850850.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049864615.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049862399.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049840383.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049862454.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049852244.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049833004.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049858304.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-432142	"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL"
XP_049831808.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049852928.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049855512.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_049827505.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049848573.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049859608.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;Reactome: R-HSA-71403	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)"
XP_049840037.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049837041.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049829750.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_049830281.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049843235.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049850701.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049833256.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049838740.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049849428.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049852857.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049838871.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049844440.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049827418.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049834217.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_049860783.1	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_049838278.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049839008.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049837942.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049828269.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049837251.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049847126.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049859045.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049846511.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049845010.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_049863715.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_049843589.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049862074.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847522.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-975634	"Clathrin-mediated endocytosis";"Chylomicron assembly";"Chylomicron remodeling";"Platelet sensitization by LDL";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"LDL remodeling";"VLDL clearance";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport"
XP_049831407.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049845655.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_049864426.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_049852009.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844301.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049852859.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049847127.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049841414.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049836362.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049830686.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049864287.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049861788.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049835942.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_049850790.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049843053.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049864073.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049861094.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049863484.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049852894.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049843152.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049857528.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049855720.1	6	Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049863764.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049846379.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049846724.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049828271.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049840487.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049859782.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049835207.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049837699.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049841231.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049852368.1	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_049839548.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049848414.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829701.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049849288.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049860297.1	16	KEGG: 00010+4.2.1.11;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-5723	"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Entner-Doudoroff pathway I";"Rubisco shunt"
XP_049849264.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049849249.1	7	Reactome: R-HSA-74217;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;MetaCyc: PWY-7807	"Purine salvage";"Adenine and adenosine salvage II";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Adenine salvage";"Neutrophil degranulation";"Glyphosate degradation III"
XP_049848428.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049827476.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_049830342.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049833429.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049856863.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049859018.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603	"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases"
XP_049859910.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049862880.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049852250.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049852071.1	5	MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176;Reactome: R-HSA-499943	"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049826916.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049835563.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049842536.1	15	MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7218;Reactome: R-HSA-70171	"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis"
XP_049839759.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria"
XP_049854189.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049832172.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049836325.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049850340.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049837039.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049855641.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049857909.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049863219.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049852942.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049829328.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049864148.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049838532.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049827892.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049835908.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049833884.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049856559.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049860709.1	17	MetaCyc: PWY-6620;Reactome: R-HSA-74259;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-7179;MetaCyc: PWY-5695;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1	"Guanine and guanosine salvage";"Purine catabolism";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism"
XP_049844439.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049843587.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049829848.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression"
XP_049861026.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049842199.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049836345.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049833960.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049846381.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049828891.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049838963.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049850184.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049859847.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852321.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_049844145.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049861285.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049853832.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation"
XP_049858928.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049828609.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049847005.1	10	Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361	"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_049856893.1	20	Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH"
XP_049837703.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049838381.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049856060.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049837309.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049837189.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_049840719.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049846918.1	12	KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049848599.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_049840047.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847455.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049863803.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049856437.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_049844938.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049831753.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049831517.1	5	Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-936964	"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049849914.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049833844.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049841050.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5358565	"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049862727.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049832987.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_049845851.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049831879.1	18	MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7198;Reactome: R-HSA-5624138;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7226	"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Trafficking of myristoylated proteins to the cilium";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_049829018.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049829796.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049838348.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049849069.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049858382.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_049852006.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630221	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing"
XP_049834649.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049834945.1	1	KEGG: 00500+2.4.1.15	"Starch and sucrose metabolism"
XP_049861091.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049864734.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-420092	"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors"
XP_049863798.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049838545.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049835493.1	179	Reactome: R-HSA-5358346;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5678895;Reactome: R-HSA-2559580;Reactome: R-HSA-5632684;Reactome: R-HSA-400253;Reactome: R-HSA-975144;Reactome: R-HSA-349425;Reactome: R-HSA-201681;Reactome: R-HSA-2644606;Reactome: R-HSA-69541;Reactome: R-HSA-977225;Reactome: R-HSA-8948751;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-110312;Reactome: R-HSA-9613829;Reactome: R-HSA-6782210;Reactome: R-HSA-9646399;Reactome: R-HSA-1236974;Reactome: R-HSA-2672351;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-1253288;Reactome: R-HSA-9633012;Reactome: R-HSA-8863795;Reactome: R-HSA-9014325;Reactome: R-HSA-72706;Reactome: R-HSA-174154;Reactome: R-HSA-937039;Reactome: R-HSA-8948747;Reactome: R-HSA-174048;Reactome: R-HSA-5685942;Reactome: R-HSA-5607761;Reactome: R-HSA-72764;Reactome: R-HSA-5357956;Reactome: R-HSA-2173796;Reactome: R-HSA-6807004;Reactome: R-HSA-5696394;Reactome: R-HSA-110320;Reactome: R-HSA-975110;Reactome: R-HSA-5668541;Reactome: R-HSA-1358803;Reactome: R-HSA-2122948;Reactome: R-HSA-1295596;Reactome: R-HSA-6804757;Reactome: R-HSA-5654732;Reactome: R-HSA-8852276;Reactome: R-HSA-8876493;Reactome: R-HSA-6781827;Reactome: R-HSA-5362768;Reactome: R-HSA-5693565;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-8866652;Reactome: R-HSA-179409;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;Reactome: R-HSA-5689877;Reactome: R-HSA-2173788;Reactome: R-HSA-5357905;Reactome: R-HSA-2565942;Reactome: R-HSA-5205685;Reactome: R-HSA-975163;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-4641263;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-2894862;Reactome: R-HSA-2559585;Reactome: R-HSA-162588;Reactome: R-HSA-69481;Reactome: R-HSA-2122947;Reactome: R-HSA-9637628;Reactome: R-HSA-72689;Reactome: R-HSA-168638;Reactome: R-HSA-175474;Reactome: R-HSA-187577;Reactome: R-HSA-937041;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-5654727;Reactome: R-HSA-1169408;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-2979096;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-6791226;Reactome: R-HSA-9615710;Reactome: R-HSA-5693607;Reactome: R-HSA-5675482;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-937042;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5696397;Reactome: R-HSA-3322077;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-917729;Reactome: R-HSA-8866654;Reactome: R-HSA-68949;Reactome: R-HSA-9645460;Reactome: R-HSA-2173795;Reactome: R-HSA-192823;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-6804760;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-5658442;Reactome: R-HSA-1799339;Reactome: R-HSA-917937;Reactome: R-HSA-9013973;Reactome: R-HSA-3785653;Reactome: R-HSA-182971;Reactome: R-HSA-901032;Reactome: R-HSA-174184;Reactome: R-HSA-8875360;Reactome: R-HSA-4641258;Reactome: R-HSA-3134975;Reactome: R-HSA-445989;Reactome: R-HSA-9636383;Reactome: R-HSA-1236382;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-168928;Reactome: R-HSA-382556;Reactome: R-HSA-5654726;Reactome: R-HSA-168927;Reactome: R-HSA-936440;Reactome: R-HSA-450302;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-8939236;Reactome: R-HSA-5684264;Reactome: R-HSA-936964;Reactome: R-HSA-450321;Reactome: R-HSA-9013507;Reactome: R-HSA-209560;Reactome: R-HSA-2559582;Reactome: R-HSA-174113;Reactome: R-HSA-110314;Reactome: R-HSA-174490;Reactome: R-HSA-8856828;Reactome: R-HSA-69231;Reactome: R-HSA-5656169;Reactome: R-HSA-4641257;Reactome: R-HSA-8849469;Reactome: R-HSA-9033241;Reactome: R-HSA-5654733;Reactome: R-HSA-912631;Reactome: R-HSA-1169091;Reactome: R-HSA-5689896;Reactome: R-HSA-2173791;Reactome: R-HSA-156827;Reactome: R-HSA-8939902;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-2691232;Reactome: R-HSA-8856825;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5655862;Reactome: R-HSA-5689880;Reactome: R-HSA-2408557;Reactome: R-HSA-205043	"Hedgehog ligand biogenesis";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Defective CFTR causes cystic fibrosis";"Oxidative Stress Induced Senescence";"Hedgehog 'on' state";"Circadian Clock";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Autodegradation of the E3 ubiquitin ligase COP1";"TCF dependent signaling in response to WNT";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Stabilization of p53";"Amyloid fiber formation";"Regulation of PTEN stability and activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"Translesion synthesis by REV1";"Chaperone Mediated Autophagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Aggrephagy";"ER-Phagosome pathway";"Stimuli-sensing channels";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Downregulation of ERBB2 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"APC/C:Cdc20 mediated degradation of Securin";"IRAK1 recruits IKK complex";"Regulation of PTEN localization";"APC/C:Cdc20 mediated degradation of Cyclin B";"HDR through Homologous Recombination (HRR)";"Dectin-1 mediated noncanonical NF-kB signaling";"Eukaryotic Translation Termination";"TNFR1-induced NFkappaB signaling pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of MET activity";"DNA Damage Recognition in GG-NER";"Translesion Synthesis by POLH";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TNFR2 non-canonical NF-kB pathway";"Downregulation of ERBB2:ERBB3 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Spry regulation of FGF signaling";"Regulation of TP53 Degradation";"Negative regulation of FGFR3 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"InlA-mediated entry of Listeria monocytogenes into host cells";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Josephin domain DUBs";"Downregulation of TGF-beta receptor signaling";"Regulation of TNFR1 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oncogene Induced Senescence";"Budding and maturation of HIV virion";"G2/M Checkpoints";"NOTCH1 Intracellular Domain Regulates Transcription";"Modulation by Mtb of host immune system";"Formation of a pool of free 40S subunits";"NOD1/2 Signaling Pathway";"Assembly Of The HIV Virion";"SCF(Skp2)-mediated degradation of p27/p21";"IKK complex recruitment mediated by RIP1";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR2 signaling";"ISG15 antiviral mechanism";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Late endosomal microautophagy";"Processing of DNA double-strand break ends";"Regulation of necroptotic cell death";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"IRAK2 mediated activation of TAK1 complex";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Glycogen synthesis";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"E3 ubiquitin ligases ubiquitinate target proteins";"Orc1 removal from chromatin";"Alpha-protein kinase 1 signaling pathway";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Viral mRNA Translation";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of TP53 Activity through Methylation";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"Regulation of RAS by GAPs";"SRP-dependent cotranslational protein targeting to membrane";"Iron uptake and transport";"TICAM1-dependent activation of IRF3/IRF7";"Myoclonic epilepsy of Lafora";"EGFR downregulation";"ER Quality Control Compartment (ERQC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of DVL";"Regulation of innate immune responses to cytosolic DNA";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Prevention of phagosomal-lysosomal fusion";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ABC-family proteins mediated transport";"Negative regulation of FGFR1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Negative regulators of DDX58/IFIH1 signaling";"activated TAK1 mediates p38 MAPK activation";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NF-kB is activated and signals survival";"Senescence-Associated Secretory Phenotype (SASP)";"SCF-beta-TrCP mediated degradation of Emi1";"Recognition of DNA damage by PCNA-containing replication complex";"Membrane binding and targetting of GAG proteins";"Clathrin-mediated endocytosis";"Cyclin D associated events in G1";"Termination of translesion DNA synthesis";"Degradation of AXIN";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Peroxisomal protein import";"Negative regulation of FGFR4 signaling";"Regulation of signaling by CBL";"Activation of NF-kappaB in B cells";"Ovarian tumor domain proteases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of RUNX2 expression and activity";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Cargo recognition for clathrin-mediated endocytosis";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Translesion synthesis by POLK";"Ub-specific processing proteases";"Selenocysteine synthesis";"NRIF signals cell death from the nucleus"
XP_049864368.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049847613.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049835896.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049853295.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_049833407.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049861269.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049828244.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049849394.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049861303.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210746	"Regulation of gene expression in beta cells";"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"
XP_049846731.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049837889.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049836085.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049864514.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049838427.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049844939.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049827600.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049850671.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049836311.1	1	KEGG: 00290+4.2.1.33	"Valine, leucine and isoleucine biosynthesis"
XP_049843509.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852409.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049828612.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049827946.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049854128.1	18	Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167243	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_049828562.1	8	Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7187	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049839878.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4"
XP_049829287.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_049864450.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049840304.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049835549.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049854267.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049856979.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049846547.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049827022.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049847896.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049864759.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049840563.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844730.1	24	Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-456926	"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049834186.1	22	Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-5659;MetaCyc: PWY-5514;MetaCyc: PWY-621;MetaCyc: PWY-3801;MetaCyc: PWY-5384;MetaCyc: PWY-6142;MetaCyc: PWY-5054;MetaCyc: PWY-7385;MetaCyc: PWY-622;Reactome: R-HSA-70263;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7347;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6981;KEGG: 00520+5.3.1.9;KEGG: 00500+5.3.1.9;Reactome: R-HSA-70171;Reactome: R-HSA-6798695;MetaCyc: PWY-6992	"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation II (sucrose synthase)";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Starch biosynthesis";"Gluconeogenesis";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis III";"Pentose phosphate pathway";"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neutrophil degranulation";"1,5-anhydrofructose degradation"
XP_049835409.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Degradation of AXIN";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_049841380.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049848710.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049833047.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049844368.1	18	KEGG: 00620+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-71064;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-70268;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;Reactome: R-HSA-70895	"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine catabolism";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism"
XP_049860654.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049847441.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049847279.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049853196.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049838938.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_049833726.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_049855274.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049844881.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_049857811.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049851046.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049831924.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-7344	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis"
XP_049857409.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049840000.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049852846.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049831770.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049831577.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049859539.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049851204.1	5	KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049857223.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049839980.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049842961.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049850891.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049831146.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_049863098.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049851420.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_049832471.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049851521.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_049846643.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049847562.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049854197.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049840112.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049832634.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850621.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_049859731.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049832166.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049836761.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049864467.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049843632.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049833359.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049827724.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_049842816.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049833730.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049854127.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049861237.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720	"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_049840536.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616	"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication"
XP_049838372.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049837144.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049844330.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-186763	"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"Downstream signal transduction"
XP_049828801.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049840737.1	21	Reactome: R-HSA-5603029;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5603027;Reactome: R-HSA-933543;Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-5357905;Reactome: R-HSA-9020702;Reactome: R-HSA-937041;Reactome: R-HSA-5684264;Reactome: R-HSA-168638;Reactome: R-HSA-5602636;Reactome: R-HSA-5357956;Reactome: R-HSA-975144;Reactome: R-HSA-1169091;Reactome: R-HSA-168927;Reactome: R-HSA-937039;Reactome: R-HSA-2871837;Reactome: R-HSA-1810476	"IkBA variant leads to EDA-ID";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"Regulation of TNFR1 signaling";"Interleukin-1 signaling";"IKK complex recruitment mediated by RIP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NOD1/2 Signaling Pathway";"IKBKB deficiency causes SCID";"TNFR1-induced NFkappaB signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"TICAM1, RIP1-mediated IKK complex recruitment";"IRAK1 recruits IKK complex";"FCERI mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_049836852.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049862341.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049834459.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_049857154.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049836168.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049834664.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049833616.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049851425.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049860671.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression"
XP_049835643.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850897.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049860497.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049858978.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049829958.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049843012.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049830611.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049843018.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049831768.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049846375.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049856055.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049845681.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049833617.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049860139.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049840300.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049861745.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049837540.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism"
XP_049829490.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049859915.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_049827465.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049830597.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049841860.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049841964.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049855964.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174154	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin"
XP_049853465.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049856097.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049862486.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049859160.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway"
XP_049849805.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049864369.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049845193.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699	"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels"
XP_049827444.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049858321.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049838562.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049853830.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049859937.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049829860.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049826897.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565	"RUNX2 regulates osteoblast differentiation";"Myogenesis";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049850742.1	32	Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-8851708	"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM"
XP_049844825.1	8	Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695	"Formation of apoptosome";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Neutrophil degranulation"
XP_049833153.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049852702.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049850994.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9610379	"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Late Events"
XP_049857228.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531	"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus"
XP_049829268.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049846097.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049858096.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049857099.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049845007.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049844297.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049858468.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049863993.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049829884.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049845794.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049844099.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049846718.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
XP_049857410.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049830997.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049852861.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_049831854.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049851813.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049851406.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049846034.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049853488.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049864571.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism"
XP_049844921.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_049864704.1	8	Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_049852739.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049839241.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049840788.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_049833965.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049844915.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049837154.1	14	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2022377;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049853563.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_049837867.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049835539.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049828600.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049847161.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049838573.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_049843955.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049842148.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_049863849.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049862667.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049862391.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862990.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049857150.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049864576.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049841929.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049845101.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049858926.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049830907.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049850237.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049858480.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049853756.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733	"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_049858266.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049832043.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049848012.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049853139.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049838993.1	12	MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4	"Selenate reduction";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfite oxidation III";"Selenocompound metabolism"
XP_049835607.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049844792.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049852618.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.21;KEGG: 00240+2.7.1.21;MetaCyc: PWY-7199	"G1/S-Specific Transcription";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage"
XP_049848421.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_049840054.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049845818.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049863518.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049846086.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049830576.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049862600.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049847010.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I"
XP_049831766.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049843568.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049832635.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049834224.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049853850.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049854060.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049858216.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049849040.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_049858280.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049851148.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049857221.1	12	Reactome: R-HSA-1839117;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Signaling by cytosolic FGFR1 fusion mutants";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049833772.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049857648.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049846653.1	5	Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88	"Proline catabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism"
XP_049844530.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25	"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch degradation V";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism"
XP_049827307.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
XP_049828113.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049841736.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_049859064.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049850638.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049851220.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049847848.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049856235.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_049845728.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049860358.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049829708.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049851964.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049854924.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049838234.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation";"Cargo concentration in the ER"
XP_049842419.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049857164.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049844000.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_049862104.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex"
XP_049841772.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049853881.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049830209.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049863234.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049849652.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049831292.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049830212.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553	"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs"
XP_049834694.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049848627.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Dual incision in TC-NER"
XP_049852986.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049834436.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5651801	"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049826901.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049850396.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049833761.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_049849313.1	20	Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-165159;KEGG: 04151+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571	"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"PI3K-Akt signaling pathway";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HSF1-dependent transactivation"
XP_049864195.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049858814.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049847494.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892	"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_049863708.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049845082.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049833257.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049859021.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049828844.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049847794.1	18	MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methane metabolism";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)"
XP_049850054.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880	"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases"
XP_049838792.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049830587.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049842337.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049833049.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049839853.1	10	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Ub-specific processing proteases";"Human papillomavirus infection";"Thermogenesis"
XP_049856879.1	7	Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism"
XP_049848999.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049842886.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049832665.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_049842642.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749	"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated"
XP_049864043.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049841780.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049853813.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049828253.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049862418.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830646.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049827425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844548.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049831101.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049864419.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_049840655.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049860173.1	5	Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049845478.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049852979.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049835478.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049855058.1	10	MetaCyc: PWY-6369;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-4661	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_049848954.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049863776.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049857311.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848006.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049864295.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049852939.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049862297.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049848876.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049828647.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049862081.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1	"Ansatrienin biosynthesis";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism"
XP_049858392.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049836857.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049849320.1	17	Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174417;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049847485.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049863857.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-611105	"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport"
XP_049840647.1	14	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-1632852;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"HCMV Early Events";"MHC class II antigen presentation";"Macroautophagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_049849536.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049832319.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049848811.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_049851790.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049842812.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049836181.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049858848.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049850355.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049847498.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049830336.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049830133.1	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049850039.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism"
XP_049846238.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049863628.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049834583.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049854471.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049839533.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049858612.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049837761.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049843048.1	5	MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_049861188.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049852277.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049848844.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049862942.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049835892.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049856102.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049859237.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049859083.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049853886.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049843409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049846308.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049849024.1	6	Reactome: R-HSA-2046106;Reactome: R-HSA-9033500;Reactome: R-HSA-390247;Reactome: R-HSA-193368;Reactome: R-HSA-389887;Reactome: R-HSA-9033241	"alpha-linolenic acid (ALA) metabolism";"TYSND1 cleaves peroxisomal proteins";"Beta-oxidation of very long chain fatty acids";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Beta-oxidation of pristanoyl-CoA";"Peroxisomal protein import"
XP_049860019.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837844.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049835254.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049829487.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049830593.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049829548.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049858929.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049862417.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049850209.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_049832749.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049841237.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049864066.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049849768.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049831391.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282	"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_049863697.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_049839086.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844041.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049852414.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049857932.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049830361.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049852591.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049852322.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_049830274.1	4	MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049845572.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049844221.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049831715.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049832854.1	17	KEGG: 00380+1.14.14.1;MetaCyc: PWY-6398;Reactome: R-HSA-211981;MetaCyc: PWY-7826;KEGG: 00071+1.14.14.1;KEGG: 00232+1.14.14.1;KEGG: 00980+1.14.14.1;KEGG: 00591+1.14.14.1;MetaCyc: PWY-7466;KEGG: 00627+1.14.14.1;MetaCyc: PWY-6992;MetaCyc: PWY-5451;KEGG: 00140+1.14.14.1;KEGG: 00830+1.14.14.1;KEGG: 00982+1.14.14.1;MetaCyc: PWY-5665;KEGG: 00590+1.14.14.1	"Tryptophan metabolism";"Melatonin degradation I";"Xenobiotics";"Amaryllidacea alkaloids biosynthesis";"Fatty acid degradation";"Caffeine metabolism";"Metabolism of xenobiotics by cytochrome P450";"Linoleic acid metabolism";"Acetone degradation III (to propane-1,2-diol)";"Aminobenzoate degradation";"1,5-anhydrofructose degradation";"Acetone degradation I (to methylglyoxal)";"Steroid hormone biosynthesis";"Retinol metabolism";"Drug metabolism - cytochrome P450";"Vanillin biosynthesis I";"Arachidonic acid metabolism"
XP_049862756.1	10	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_049846312.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049847488.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049835910.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049839083.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049858910.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049840712.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049852922.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049841939.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis"
XP_049829736.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049852897.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049860611.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_049847401.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049828223.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049836038.1	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049846896.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"Nephrin family interactions";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth"
XP_049856492.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049835924.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049861430.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049858297.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049833023.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049843605.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049848700.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049845614.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-381340	"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of white adipocyte differentiation"
XP_049834358.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049838388.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049829876.1	11	KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964	"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II"
XP_049827777.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049860820.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049858118.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049862227.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049844148.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_049843800.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049827463.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049836637.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049833085.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049848925.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049849041.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049857387.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049828154.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049843563.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049848480.1	13	Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"Aggrephagy";"Josephin domain DUBs";"Protein methylation";"Ovarian tumor domain proteases";"HSF1 activation";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_049829483.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049832601.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049862075.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049827943.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049848600.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049847381.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049826994.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049841428.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049840276.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519	"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression"
XP_049862554.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049850483.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049829802.1	11	Reactome: R-HSA-191273;MetaCyc: PWY-7560;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6174;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-922;MetaCyc: PWY-5123;MetaCyc: PWY-7102	"Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_049842954.1	4	Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC"
XP_049829754.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049845789.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049846195.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049834723.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049850250.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_049854777.1	25	Reactome: R-HSA-8939247;Reactome: R-HSA-8941284;Reactome: R-HSA-8939246;Reactome: R-HSA-8939242;Reactome: R-HSA-8939256;Reactome: R-HSA-8939243;Reactome: R-HSA-8934593;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8939245;Reactome: R-HSA-8941326;Reactome: R-HSA-8936459;Reactome: R-HSA-8941332;Reactome: R-HSA-8949275;Reactome: R-HSA-8931987;Reactome: R-HSA-8935964;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8939902;Reactome: R-HSA-8941333;Reactome: R-HSA-9616222;Reactome: R-HSA-8941858;Reactome: R-HSA-8878166;Reactome: R-HSA-8940973;Reactome: R-HSA-8951911	"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates bone development";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates genes involved in cell migration";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates expression of components of tight junctions";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX2 expression and activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX3 expression and activity";"Transcriptional regulation by RUNX2";"RUNX2 regulates osteoblast differentiation";"RUNX3 regulates RUNX1-mediated transcription"
XP_049833778.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049848632.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049829914.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049857233.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049848351.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049830909.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049832974.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049857054.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049835671.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049844552.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049857237.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049856495.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049853671.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049831771.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049848256.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049837201.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049829394.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049833732.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049848524.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049829970.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049853448.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049833843.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049861112.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049830766.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049864385.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049864177.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049830696.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049853047.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049863994.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049837680.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128	"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling"
XP_049857126.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049854808.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049845848.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_049844544.1	33	Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107	"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_049840827.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850618.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049864271.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049828780.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_049835636.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049838935.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049849991.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692	"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity"
XP_049855384.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049841610.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049832602.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049844335.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_049838701.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049850518.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049830978.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049841519.1	5	KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_049852854.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049839850.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_049854606.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049858938.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049836412.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049827219.1	6	MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952	"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation"
XP_049832575.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049828241.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381070	"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones"
XP_049830590.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049845899.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049853442.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049844771.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049853490.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049849339.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049835883.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049864703.1	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_049847234.1	19	Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;MetaCyc: PWY-5537	"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"Pyruvate fermentation to acetate V"
XP_049862663.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049833077.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049828067.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism"
XP_049834672.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049828665.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049851157.1	16	Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174154	"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin"
XP_049862680.1	7	MetaCyc: PWY-5697;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698	"Allantoin degradation to ureidoglycolate I (urea producing)";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)"
XP_049849171.1	10	MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00030+2.2.1.1;MetaCyc: PWY-6901;MetaCyc: PWY-7560;MetaCyc: PWY-6892;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00900+2.2.1.7;KEGG: 00710+2.2.1.1	"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Pentose phosphate pathway";"Superpathway of glucose and xylose degradation";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Terpenoid backbone biosynthesis";"Carbon fixation in photosynthetic organisms"
XP_049833769.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049851362.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049849784.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049850666.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049832922.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049837483.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049862403.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049841540.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049863929.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism"
XP_049836045.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049864318.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER"
XP_049837784.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049859230.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049830467.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049830066.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049850012.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049849148.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049856454.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049851905.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049841677.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049860571.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049847994.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination"
XP_049828072.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049838157.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049848869.1	8	KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_049863317.1	11	MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-5381;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7821	"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Purine metabolism";"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis"
XP_049834287.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_049828150.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049860648.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_049839204.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049858584.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049857225.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049860192.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049856410.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049845758.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049857822.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049859161.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway"
XP_049850487.1	42	MetaCyc: PWY-7654;KEGG: 00623+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6945;MetaCyc: PWY-7779;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00410+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6583;MetaCyc: PWY-7778;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-5789;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7216;MetaCyc: PWY-7401	"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Toluene degradation";"Phenylalanine metabolism";"Butanoate metabolism";"Fatty acid salvage";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Benzoate degradation";"Butanoate metabolism";"Limonene and pinene degradation";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)"
XP_049861343.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838850.1	7	Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886	"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_049848233.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049856228.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049840399.1	7	MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049828707.1	5	Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_049863627.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4"
XP_049840499.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049840041.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_049849936.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049847526.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049849801.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_049838363.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049832587.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049861686.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049851671.1	4	KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_049844139.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049841427.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049844363.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_049839881.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049849358.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049830337.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049857951.1	8	MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739;MetaCyc: PWY-7573;Reactome: R-HSA-6787639	"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis"
XP_049860544.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_049852650.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049843073.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049848195.1	14	KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_049844829.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049843585.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049844161.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049832527.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049842960.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049838929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049854479.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049831021.1	58	MetaCyc: PWY-7216;Reactome: R-HSA-77346;Reactome: R-HSA-77305;MetaCyc: PWY-7401;Reactome: R-HSA-77285;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-6435;KEGG: 00720+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-5136;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00280+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6583;Reactome: R-HSA-77288;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6945;MetaCyc: PWY-5138;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;Reactome: R-HSA-77350;MetaCyc: PWY-7654;KEGG: 00650+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77348;KEGG: 00380+4.2.1.17;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361	"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Caprolactam degradation";"2-methylpropene degradation";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"beta-Alanine metabolism";"Geraniol degradation";"Benzoate degradation";"Butanoate metabolism";"Limonene and pinene degradation";"Tryptophan metabolism";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"Benzoate degradation";"Geraniol degradation";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Carbon fixation pathways in prokaryotes";"Acyl chain remodeling of CL";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"Toluene degradation";"Phenylalanine metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Fatty acid salvage";"Fatty acid degradation";"Caprolactam degradation";"Benzoyl-coa degradation I (aerobic)"
XP_049863266.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049857084.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049864242.1	9	Reactome: R-HSA-446193;Reactome: R-HSA-5633231;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00510+2.4.1.141;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)"
XP_049856595.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049852697.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049844731.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-418217	"G alpha (i) signalling events";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta"
XP_049826987.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049851793.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049838621.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049858411.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049844593.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049844708.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049854303.1	58	Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5689901;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Metalloprotease DUBs";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling"
XP_049850182.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049845344.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049827786.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049838603.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049862650.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049840166.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049832564.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049838244.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-6798695	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Neutrophil degranulation"
XP_049828304.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049857905.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049855526.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049850344.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049860197.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049853636.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049858908.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049829511.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049864367.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049843372.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049864739.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-8964315	"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK"
XP_049832901.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049826898.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236	"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049850156.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049828403.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735	"beta-Alanine metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis"
XP_049835229.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049844883.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049844061.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy"
XP_049855562.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049834085.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_049858340.1	5	Reactome: R-HSA-8951664;Reactome: R-HSA-8849473;Reactome: R-HSA-1234176;Reactome: R-HSA-1234158;Reactome: R-HSA-1234174	"Neddylation";"PTK6 Expression";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of gene expression by Hypoxia-inducible Factor";"Cellular response to hypoxia"
XP_049848826.1	6	MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622	"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)"
XP_049840421.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049862410.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844267.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049838497.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049830006.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049827024.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049852655.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049847302.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049857249.1	20	Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04150+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"mTOR signaling pathway"
XP_049838194.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049837647.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049862866.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049830908.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049850829.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049831494.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049854436.1	5	KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210	"Purine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049862015.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_049847609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049845956.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049839391.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464	"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins"
XP_049851202.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium"
XP_049852815.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049861550.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049836912.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_049848415.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049850335.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049843263.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049840159.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049830915.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049836853.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049832017.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049860537.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049852574.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049848967.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049829345.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049859248.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049859241.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049838708.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049838504.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_049864273.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049838179.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049831385.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049859418.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049861376.1	10	MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
XP_049837485.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049839549.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049838887.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049835855.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049847500.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_049844276.1	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680	"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity"
XP_049835004.1	14	Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-5690	"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)"
XP_049849486.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049864272.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049846217.1	5	Reactome: R-HSA-3299685;Reactome: R-HSA-5668599;Reactome: R-HSA-1236973;Reactome: R-HSA-4420097;Reactome: R-HSA-1222556	"Detoxification of Reactive Oxygen Species";"RHO GTPases Activate NADPH Oxidases";"Cross-presentation of particulate exogenous antigens (phagosomes)";"VEGFA-VEGFR2 Pathway";"ROS and RNS production in phagocytes"
XP_049862751.1	10	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_049833432.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2	"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049831321.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049834585.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049832059.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones"
XP_049849531.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049829877.1	11	Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;Reactome: R-HSA-8964539;MetaCyc: PWY-6963	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I"
XP_049829226.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049855753.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049831793.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049856728.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049848692.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049854785.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848447.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049826917.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049864158.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049848228.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049858966.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049844005.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"HATs acetylate histones";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
XP_049846016.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848021.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049858097.1	10	MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385	"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049852852.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049838430.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049841817.1	30	Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-389357;Reactome: R-HSA-9634638;Reactome: R-HSA-6804759;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-111447;Reactome: R-HSA-69202;Reactome: R-HSA-6804758;Reactome: R-HSA-8876198;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-211163;Reactome: R-HSA-392451;Reactome: R-HSA-198693;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-199418	"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Regulation of localization of FOXO transcription factors";"CD28 dependent PI3K/Akt signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Association with Co-factors";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"RUNX2 regulates genes involved in cell migration";"Activation of BAD and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Regulation of TP53 Activity through Acetylation";"RAB GEFs exchange GTP for GDP on RABs";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"Regulation of PTEN stability and activity";"AKT-mediated inactivation of FOXO1A";"G beta:gamma signalling through PI3Kgamma";"AKT phosphorylates targets in the nucleus";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Human papillomavirus infection";"Negative regulation of the PI3K/AKT network"
XP_049846180.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049863318.1	11	MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-5695;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608	"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation III"
XP_049839636.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049845676.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049827189.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049856090.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_049837120.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049829100.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049843730.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049839713.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049835871.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049836782.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049841092.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049839243.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_049829757.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049832325.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049844905.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_049845909.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049845106.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838293.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049845115.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049864170.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049849145.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049854433.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049842968.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049846583.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049849639.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049848546.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049843373.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049850655.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_049829169.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049856057.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049838361.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049863924.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049857125.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049854815.1	11	KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-7124	"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)"
XP_049849175.1	11	Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_049863747.1	6	Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509	"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling"
XP_049862893.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593	"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity"
XP_049836166.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049851650.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049842972.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049836890.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_049853534.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049832128.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049857312.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049853723.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049849567.1	6	KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PA";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049830031.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049857239.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049864528.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049844695.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
XP_049833877.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049860295.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7227;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049844229.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049834485.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049832562.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049831869.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049847839.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049839844.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049853522.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049853141.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049827212.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049861035.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52	"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049860479.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_049851502.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049849747.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049838375.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049833639.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049835495.1	179	Reactome: R-HSA-156827;Reactome: R-HSA-8939902;Reactome: R-HSA-5689901;Reactome: R-HSA-6783310;Reactome: R-HSA-2691232;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-8856825;Reactome: R-HSA-5655862;Reactome: R-HSA-5689880;Reactome: R-HSA-205043;Reactome: R-HSA-2408557;Reactome: R-HSA-69231;Reactome: R-HSA-4641257;Reactome: R-HSA-5656169;Reactome: R-HSA-9033241;Reactome: R-HSA-8849469;Reactome: R-HSA-5654733;Reactome: R-HSA-912631;Reactome: R-HSA-1169091;Reactome: R-HSA-2173791;Reactome: R-HSA-5689896;Reactome: R-HSA-5684264;Reactome: R-HSA-936964;Reactome: R-HSA-9013507;Reactome: R-HSA-450321;Reactome: R-HSA-209560;Reactome: R-HSA-174113;Reactome: R-HSA-2559582;Reactome: R-HSA-8856828;Reactome: R-HSA-174490;Reactome: R-HSA-110314;Reactome: R-HSA-168928;Reactome: R-HSA-382556;Reactome: R-HSA-5654726;Reactome: R-HSA-450302;Reactome: R-HSA-936440;Reactome: R-HSA-168927;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-8875360;Reactome: R-HSA-174184;Reactome: R-HSA-445989;Reactome: R-HSA-3134975;Reactome: R-HSA-4641258;Reactome: R-HSA-1236382;Reactome: R-HSA-9636383;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-917937;Reactome: R-HSA-9013973;Reactome: R-HSA-3785653;Reactome: R-HSA-182971;Reactome: R-HSA-901032;Reactome: R-HSA-9020702;Reactome: R-HSA-5696395;Reactome: R-HSA-917729;Reactome: R-HSA-8866654;Reactome: R-HSA-192823;Reactome: R-HSA-2173795;Reactome: R-HSA-9645460;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-6804760;Reactome: R-HSA-9604323;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-1799339;Reactome: R-HSA-5658442;Reactome: R-HSA-6791226;Reactome: R-HSA-195253;Reactome: R-HSA-9615710;Reactome: R-HSA-5693607;Reactome: R-HSA-937042;Reactome: R-HSA-6781823;Reactome: R-HSA-5675482;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-937041;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-1169408;Reactome: R-HSA-5654727;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-2979096;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-975957;Reactome: R-HSA-4641263;Reactome: R-HSA-2894862;Reactome: R-HSA-450408;Reactome: R-HSA-2559585;Reactome: R-HSA-162588;Reactome: R-HSA-9637628;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-72689;Reactome: R-HSA-168638;Reactome: R-HSA-175474;Reactome: R-HSA-2173788;Reactome: R-HSA-5357905;Reactome: R-HSA-2565942;Reactome: R-HSA-975163;Reactome: R-HSA-5205685;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-937072;Reactome: R-HSA-8852276;Reactome: R-HSA-5654732;Reactome: R-HSA-6804757;Reactome: R-HSA-8876493;Reactome: R-HSA-5362768;Reactome: R-HSA-6781827;Reactome: R-HSA-5693565;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-8866652;Reactome: R-HSA-179409;Reactome: R-HSA-69601;Reactome: R-HSA-5689877;Reactome: R-HSA-6804756;Reactome: R-HSA-975110;Reactome: R-HSA-110320;Reactome: R-HSA-5668541;Reactome: R-HSA-1358803;Reactome: R-HSA-2122948;Reactome: R-HSA-1295596;Reactome: R-HSA-8863795;Reactome: R-HSA-5676590;Reactome: R-HSA-1253288;Reactome: R-HSA-9633012;Reactome: R-HSA-174154;Reactome: R-HSA-72706;Reactome: R-HSA-9014325;Reactome: R-HSA-8948747;Reactome: R-HSA-937039;Reactome: R-HSA-5607761;Reactome: R-HSA-5685942;Reactome: R-HSA-174048;Reactome: R-HSA-72764;Reactome: R-HSA-6807004;Reactome: R-HSA-2173796;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-201681;Reactome: R-HSA-349425;Reactome: R-HSA-977225;Reactome: R-HSA-69541;Reactome: R-HSA-8948751;Reactome: R-HSA-2644606;Reactome: R-HSA-110312;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-6782210;Reactome: R-HSA-5689603;Reactome: R-HSA-2672351;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-2559580;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-400253;Reactome: R-HSA-975144	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of RUNX2 expression and activity";"Metalloprotease DUBs";"Fanconi Anemia Pathway";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Cargo recognition for clathrin-mediated endocytosis";"Translesion synthesis by POLK";"Ub-specific processing proteases";"NRIF signals cell death from the nucleus";"Selenocysteine synthesis";"Cyclin D associated events in G1";"Degradation of AXIN";"Termination of translesion DNA synthesis";"Peroxisomal protein import";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR4 signaling";"Regulation of signaling by CBL";"Activation of NF-kappaB in B cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Ovarian tumor domain proteases";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NF-kB is activated and signals survival";"SCF-beta-TrCP mediated degradation of Emi1";"Senescence-Associated Secretory Phenotype (SASP)";"Clathrin-mediated endocytosis";"Membrane binding and targetting of GAG proteins";"Recognition of DNA damage by PCNA-containing replication complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ABC-family proteins mediated transport";"Negative regulation of FGFR1 signaling";"activated TAK1 mediates p38 MAPK activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of innate immune responses to cytosolic DNA";"Degradation of DVL";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Prevention of phagosomal-lysosomal fusion";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Iron uptake and transport";"TICAM1-dependent activation of IRF3/IRF7";"Myoclonic epilepsy of Lafora";"EGFR downregulation";"ER Quality Control Compartment (ERQC)";"Interleukin-1 signaling";"Formation of Incision Complex in GG-NER";"Endosomal Sorting Complex Required For Transport (ESCRT)";"E3 ubiquitin ligases ubiquitinate target proteins";"Viral mRNA Translation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Alpha-protein kinase 1 signaling pathway";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of TP53 Activity through Methylation";"Negative regulation of NOTCH4 signaling";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of RAS by GAPs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of beta-catenin by the destruction complex";"Late endosomal microautophagy";"Processing of DNA double-strand break ends";"IRAK2 mediated activation of TAK1 complex";"Formation of TC-NER Pre-Incision Complex";"Regulation of necroptotic cell death";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Glycogen synthesis";"IKK complex recruitment mediated by RIP1";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"ISG15 antiviral mechanism";"Negative regulation of FGFR2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of FZD by ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oncogene Induced Senescence";"Budding and maturation of HIV virion";"Modulation by Mtb of host immune system";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Formation of a pool of free 40S subunits";"NOD1/2 Signaling Pathway";"Assembly Of The HIV Virion";"Downregulation of TGF-beta receptor signaling";"Regulation of TNFR1 signaling";"Regulation of PLK1 Activity at G2/M Transition";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR3 signaling";"Regulation of TP53 Degradation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Josephin domain DUBs";"Regulation of TP53 Activity through Phosphorylation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Translesion Synthesis by POLH";"TNFR2 non-canonical NF-kB pathway";"Downregulation of ERBB2:ERBB3 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Spry regulation of FGF signaling";"Downregulation of ERBB2 signaling";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"APC/C:Cdc20 mediated degradation of Securin";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of PTEN localization";"IRAK1 recruits IKK complex";"Dectin-1 mediated noncanonical NF-kB signaling";"HDR through Homologous Recombination (HRR)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Eukaryotic Translation Termination";"Negative regulation of MET activity";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"TCF dependent signaling in response to WNT";"Autodegradation of the E3 ubiquitin ligase COP1";"Amyloid fiber formation";"Stabilization of p53";"Regulation of PTEN stability and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Translesion synthesis by REV1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"Chaperone Mediated Autophagy";"Aggrephagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"UCH proteinases";"Stimuli-sensing channels";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Oxidative Stress Induced Senescence";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Circadian Clock";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049831787.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049831429.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113	"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049852809.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049843037.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_049864620.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049852189.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049845083.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049827155.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049863316.1	11	MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7821;MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I"
XP_049848507.1	6	KEGG: 00790+4.1.2.25;MetaCyc: PWY-6147;MetaCyc: PWY-6148;MetaCyc: PWY-6797;Reactome: R-HSA-1474151;MetaCyc: PWY-7539	"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydromethanopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)"
XP_049850169.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049837900.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049838633.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049837132.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049845669.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049854666.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848654.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049847162.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049855776.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049860499.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049837663.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049834453.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049859570.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049862939.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049861705.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049859486.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_049833040.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049829871.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-6804756	"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation"
XP_049858414.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049841956.1	10	MetaCyc: PWY-6366;MetaCyc: PWY-6554;Reactome: R-HSA-983231;MetaCyc: PWY-6365;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204;MetaCyc: PWY-4661;MetaCyc: PWY-6362	"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_049829692.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049830303.1	12	MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5857	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049852408.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049862651.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049860378.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049842933.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049841290.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049862367.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_049862601.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049836276.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049831100.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049854344.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049853732.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049863405.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049863668.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049840817.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049854421.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049846701.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049852786.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049852727.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049849286.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049857716.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049839963.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844279.1	11	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation"
XP_049837461.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049836955.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049858350.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049858715.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049844178.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049849929.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049856216.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049840662.1	17	KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2	"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Propanoate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Carnitine metabolism";"Pyruvate metabolism"
XP_049855777.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049846942.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049835281.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049859375.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-210744	"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Attenuation phase";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_049847806.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5358346	"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis"
XP_049832592.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049832044.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049840045.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049845847.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049839839.1	10	KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Human immunodeficiency virus 1 infection"
XP_049846745.1	6	Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9640463;Reactome: R-HSA-2426168	"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Wax biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049862220.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_049839775.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049855310.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049859594.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049853883.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049853822.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049858907.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049847832.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049858325.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049831985.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049863783.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049856998.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049856712.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049838155.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_049837885.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049832559.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049852559.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049827215.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049838714.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049829207.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049848135.1	8	MetaCyc: PWY-6168;KEGG: 00790+3.5.4.25;KEGG: 00740+4.1.99.12;KEGG: 00740+2.5.1.78;MetaCyc: PWY-7539;MetaCyc: PWY-7991;KEGG: 00740+3.5.4.25;MetaCyc: PWY-6167	"Flavin biosynthesis III (fungi)";"Folate biosynthesis";"Riboflavin metabolism";"Riboflavin metabolism";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)";"Toxoflavin biosynthesis";"Riboflavin metabolism";"Flavin biosynthesis II (archaea)"
XP_049831320.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049860387.1	11	Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-6811436	"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049832416.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049840036.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049860036.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049830986.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049864331.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049830220.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049838854.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842	"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"HDMs demethylate histones"
XP_049840527.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049829546.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049838992.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932	"Selenocompound metabolism";"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfur metabolism";"Selenate reduction"
XP_049858512.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049843211.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049841518.1	5	KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_049831228.1	10	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation"
XP_049840371.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_049846383.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049837847.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049857569.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049851223.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690	"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"HCMV Late Events";"HCMV Early Events"
XP_049844259.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049829338.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049860328.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049856804.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049851322.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049833215.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049829932.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049835886.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049830689.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049838737.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049843569.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049864191.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049843570.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049853080.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049836647.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844719.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049838768.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_049852866.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049832599.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049850328.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049857433.1	3	Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation"
XP_049863056.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049859328.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049833086.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049851993.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049835885.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049831832.1	5	Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702	"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling"
XP_049854820.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049841223.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049853215.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_049833683.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049846307.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049839244.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049859912.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049848665.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049855014.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049858162.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049834048.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049845102.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049864174.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049835835.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049831535.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049831579.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049853220.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex"
XP_049846399.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026	"LDL clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"VLDL assembly";"VLDL clearance";"Scavenging by Class B Receptors";"LDL remodeling";"Chylomicron remodeling";"Platelet sensitization by LDL";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance"
XP_049845704.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049840717.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049827434.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049841323.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049833147.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049847293.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049834023.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049864473.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049852197.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978	"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_049850278.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049853094.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049859327.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049864654.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_049862529.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049841174.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049855200.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
XP_049859889.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_049844499.1	10	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"RSK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection"
XP_049856862.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049831207.1	10	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049832478.1	2	Reactome: R-HSA-606279;Reactome: R-HSA-6783310	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway"
XP_049832211.1	20	MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7227;Reactome: R-HSA-499943;Reactome: R-HSA-380320;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049850516.1	33	Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159236	"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049857562.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_049858916.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049849302.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049862761.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_049846311.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049858965.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049844846.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049844324.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_049859525.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049845817.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049827235.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049838990.1	12	MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4	"Sulfite oxidation III";"Selenocompound metabolism";"Selenate reduction";"Sulfur metabolism";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism"
XP_049858089.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_049828206.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049839159.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049840002.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049858817.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049849798.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049863531.1	8	Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)"
XP_049848453.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049835541.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049861490.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049852224.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049844465.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_049848352.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049854694.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049831015.1	5	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Triglyceride biosynthesis"
XP_049860845.1	24	Reactome: R-HSA-5607764;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 05165+2.7.11.1;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1	"CLEC7A (Dectin-1) signaling";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"Human papillomavirus infection";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"Activation of AKT2";"PIP3 activates AKT signaling";"Integrin signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Human cytomegalovirus infection"
XP_049839679.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049839851.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_049849654.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346	"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis"
XP_049850616.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049840578.1	7	MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11	"3-phosphoinositide biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_049860603.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-442982	"Interferon gamma signaling";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049858674.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_049852088.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_049847420.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049835837.1	5	KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527	"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation"
XP_049847491.1	16	Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-8853659;Reactome: R-HSA-194840	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"RET signaling";"Rho GTPase cycle"
XP_049863152.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049830364.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049864226.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049859095.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049858069.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049830213.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions"
XP_049857302.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049843576.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049828786.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049855244.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049845702.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049849967.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049861863.1	14	Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Triglyceride biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_049843093.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049861805.1	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055	"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_049864570.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049862852.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049855583.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049858471.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049835880.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049845675.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049847838.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049834008.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_049836354.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854705.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_049853650.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049864162.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049853677.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049853939.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049838857.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049839388.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049863617.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801	"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049850866.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049837631.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049862854.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049834061.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_049830760.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049860450.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_049848830.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049849656.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049853185.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049835475.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049838915.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049855895.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049852437.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049831305.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_049848207.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049838696.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"PPARA activates gene expression";"HCMV Early Events"
XP_049845530.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049833207.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049830880.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862652.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049861186.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049833776.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049835759.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049863179.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049862502.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049848246.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049864063.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049856223.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049829382.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049861855.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049843074.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049840661.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789	"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Carnitine metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049845710.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049857029.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049860133.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_049838038.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_049838423.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049862698.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049851303.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049843069.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049828560.1	8	MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049845905.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049860379.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049854788.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049828256.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049833816.1	5	KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_049833951.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049847487.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049837095.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049851903.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049855811.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049837528.1	11	Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;Reactome: R-HSA-168138	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade"
XP_049831572.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049832996.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_049849338.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049844445.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049832647.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049830297.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049856752.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049836542.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression"
XP_049859848.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049859709.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049853222.1	17	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Fanconi Anemia Pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis"
XP_049832177.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049834255.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049851460.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049837344.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049847998.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049847504.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049857404.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049862654.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049860580.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9617324	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049835637.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049847249.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049847278.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049849019.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049830107.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049850067.1	11	MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-7124;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes"
XP_049833064.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049858699.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049834525.1	4	MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_049849396.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049858178.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049838969.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049842186.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-445144	"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1"
XP_049827174.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049848868.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism"
XP_049863368.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049829275.1	10	MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484	"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_049829760.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049850397.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049853666.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049828259.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049860910.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049829988.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049830946.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_049858705.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-165054	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA"
XP_049838988.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932	"Selenocompound metabolism";"Sulfite oxidation III";"Purine metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Selenate reduction"
XP_049863969.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049848088.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049846943.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049856409.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049843609.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049856056.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049855264.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40	"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049841937.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049831632.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049828195.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049854598.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"HSF1-dependent transactivation"
XP_049831330.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049840071.1	10	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-71737;Reactome: R-HSA-9640463;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Pyrophosphate hydrolysis";"Wax biosynthesis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Cutin, suberine and wax biosynthesis"
XP_049833132.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049838607.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049833119.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-5723	"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt"
XP_049829978.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_049860170.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_049853853.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_049833907.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049856868.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_049828402.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)"
XP_049832983.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_049853735.1	1	Reactome: R-HSA-8856825	"Cargo recognition for clathrin-mediated endocytosis"
XP_049837755.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049863704.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049830508.1	18	MetaCyc: PWY-6643;MetaCyc: PWY-6642;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1	"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Tyrosine metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis"
XP_049855644.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049829423.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049833053.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_049848985.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_049864283.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049827426.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862608.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049833375.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049863861.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049864584.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049832580.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049849969.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_049837869.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049850273.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864155.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838141.1	14	MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5078;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-7767;MetaCyc: PWY-5104	"L-leucine degradation III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV"
XP_049864560.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_049844134.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049827019.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049839997.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049838964.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049852256.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049838178.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049850895.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049858412.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049849854.1	12	Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167287	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery"
XP_049860835.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049849662.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049853940.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049861593.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049851210.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-195253	"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex"
XP_049828225.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049862326.1	11	KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686	"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_049859049.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049860447.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049853278.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049839902.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049827101.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049832318.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_049852284.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049852049.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049844281.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049853851.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049856225.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049838632.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049846169.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049831410.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_049850893.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049863087.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049863763.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049844110.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049837616.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis"
XP_049835876.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049848464.1	25	Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257	"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion"
XP_049837850.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049836153.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049858719.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049861687.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049856237.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_049858718.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049835408.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880	"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases"
XP_049849478.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049835992.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049849616.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049837096.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049847681.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049862184.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049831861.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049864387.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049862660.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049829782.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system"
XP_049853530.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049841102.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783	"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome"
XP_049842542.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049845197.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049836037.1	5	MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049862416.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049863348.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049847290.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049835840.1	5	KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_049863392.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049859735.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
XP_049830049.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049831590.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049848449.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049827787.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049845656.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_049845645.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049863485.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049860296.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_049859446.1	11	Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1	"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway"
XP_049849968.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_049853034.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_049830388.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-180585	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G"
XP_049849859.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK"
XP_049827139.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049828556.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049832427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049846914.1	12	KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7817	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049837385.1	40	KEGG: 00360+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7094;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6945;MetaCyc: PWY-5138;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7007;MetaCyc: PWY-5109;MetaCyc: PWY-7778;MetaCyc: PWY-5789;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-7656;MetaCyc: PWY-6946;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7401	"Phenylalanine metabolism";"Toluene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Caprolactam degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid salvage";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Methyl tert-butyl ether degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"beta-Alanine metabolism";"Tryptophan metabolism";"Butanoate metabolism";"Limonene and pinene degradation";"Benzoate degradation";"Pyruvate fermentation to butanol I";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Lysine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)"
XP_049861076.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049853204.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049853577.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049833612.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049835425.1	5	KEGG: 00240+2.7.1.21;KEGG: 00983+2.7.1.21;Reactome: R-HSA-73614;Reactome: R-HSA-69205;MetaCyc: PWY-7199	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage"
XP_049864067.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049846007.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381070	"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones"
XP_049858695.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049861769.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049835913.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049860826.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049839380.1	4	MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_049849976.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049834326.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049844751.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049861259.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049835485.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049861253.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049841467.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049835489.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_049837027.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049852445.1	10	MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9	"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes"
XP_049862438.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844107.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049830287.1	5	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"DNA methylation"
XP_049864236.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049833725.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_049864342.1	5	Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007	"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events"
XP_049853620.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049850769.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049847875.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049863233.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864640.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049852641.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049831468.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049829318.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049846384.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049830227.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049854968.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049845006.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049860822.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049847490.1	16	Reactome: R-HSA-114604;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-1266695	"GPVI-mediated activation cascade";"RET signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling"
XP_049846374.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049834489.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049861617.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049827074.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049830205.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553	"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs"
XP_049830449.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049851225.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"snRNP Assembly";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049832480.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049850519.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049837291.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049838571.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_049864175.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049842180.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903	"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy"
XP_049853265.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049851766.1	3	KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_049846646.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049828405.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)"
XP_049856018.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex"
XP_049857915.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049853239.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049860965.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049854800.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049835673.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049845160.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049828356.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482	"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events"
XP_049847520.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-975634	"Chylomicron assembly";"Platelet sensitization by LDL";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"VLDL assembly";"Scavenging by Class B Receptors";"VLDL clearance";"LDL remodeling";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport"
XP_049838801.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049835449.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049838526.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049843324.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432720;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049853686.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049836031.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049860543.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-442982	"Interferon gamma signaling";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049829560.1	5	Reactome: R-HSA-381038;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-901032	"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)"
XP_049857281.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049854266.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049849948.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049829249.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049839562.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049854110.1	22	MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7053;Reactome: R-HSA-75876;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601	"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049862452.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049829509.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049853860.1	4	MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50	"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_049830734.1	9	MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590	"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation"
XP_049852945.1	6	KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_049836446.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049862621.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-1042	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_049852451.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049832638.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049858100.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_049853191.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049853024.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049849949.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049858316.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049834265.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049830080.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049863229.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049859442.1	10	KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153	"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049830471.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049860183.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049848533.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049829245.1	10	KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;MetaCyc: PWY-5691;MetaCyc: PWY-7849	"Purine metabolism";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Neutrophil degranulation";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I";"Urate conversion to allantoin III"
XP_049856504.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049836695.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_049838706.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049831334.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049849220.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049827642.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049855754.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049862653.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049842222.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049862147.1	18	KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1	"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Tyrosine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism"
XP_049843580.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049829899.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049848290.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049829784.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_049847698.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049852020.1	3	MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57	"Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism"
XP_049848224.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049859232.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049841227.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_049856037.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049864061.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049844876.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049832018.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7807;MetaCyc: PWY-7805;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-6605	"Neutrophil degranulation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Adenine salvage";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage II"
XP_049849866.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049849016.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049832572.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049841946.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049856207.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049837881.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049831392.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_049846294.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049848965.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049839731.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049842340.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049835452.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049834815.1	43	Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-202670;Reactome: R-HSA-5358751;Reactome: R-HSA-2995383;Reactome: R-HSA-69231;Reactome: R-HSA-975957;Reactome: R-HSA-2465910;Reactome: R-HSA-68877;Reactome: R-HSA-113501;Reactome: R-HSA-1295596;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-6811558;Reactome: R-HSA-9634600;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-163767;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-5339716;Reactome: R-HSA-163685;Reactome: R-HSA-198753;Reactome: R-HSA-6804757;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-380259;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180024;Reactome: R-HSA-5467340;Reactome: R-HSA-2565942	"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"ERKs are inactivated";"S45 mutants of beta-catenin aren't phosphorylated";"Initiation of Nuclear Envelope Reformation";"Cyclin D associated events in G1";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"MASTL Facilitates Mitotic Progression";"Mitotic Prometaphase";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Spry regulation of FGF signaling";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PP2A-mediated dephosphorylation of key metabolic factors";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Misspliced GSK3beta mutants stabilize beta-catenin";"Integration of energy metabolism";"ERK/MAPK targets";"Regulation of TP53 Degradation";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Loss of Nlp from mitotic centrosomes";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"DARPP-32 events";"AXIN missense mutants destabilize the destruction complex";"Regulation of PLK1 Activity at G2/M Transition"
XP_049853665.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049861167.1	7	MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;Reactome: R-HSA-389661;MetaCyc: PWY-8088;MetaCyc: PWY-5097;MetaCyc: PWY-2941	"L-lysine biosynthesis III";"Monobactam biosynthesis";"Lysine biosynthesis";"Glyoxylate metabolism and glycine degradation";"Dipicolinate biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis II"
XP_049833056.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049833065.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862429.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049857250.1	20	Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"VEGFR2 mediated vascular permeability";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"mTOR signalling";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Human papillomavirus infection";"HSF1-dependent transactivation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049829216.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049837760.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049833131.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_049842493.1	2	KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_049857969.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049843511.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049851661.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049848554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049850592.1	10	Reactome: R-HSA-196757;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9	"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes"
XP_049861202.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049859962.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049829949.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049828845.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049860496.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049848681.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049829771.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049842660.1	18	MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism"
XP_049844513.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833304.1	10	Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-202424	"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling"
XP_049850459.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4	"Ether lipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049827599.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049845642.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049864166.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049851702.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049833500.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049864463.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049833717.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049862887.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation"
XP_049864708.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049837121.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049859796.1	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049859457.1	11	Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097	"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049827470.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049844549.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049851053.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion"
XP_049844781.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049833757.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049845132.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049859056.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049846226.1	4	KEGG: 00500+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263	"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_049830266.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_049852978.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049843448.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049849333.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049863593.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049849696.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
XP_049862825.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049833727.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_049857861.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049841285.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049830010.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049863607.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049831568.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049847665.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049834022.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049827641.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049833565.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation"
XP_049831759.1	8	Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-191273	"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis"
XP_049838130.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049862493.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049836234.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049838076.1	7	Reactome: R-HSA-70635;MetaCyc: PWY-31;MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46	"Urea cycle";"Canavanine degradation";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III"
XP_049830588.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049833282.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049861124.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049843581.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049853480.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049837103.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049833619.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049842410.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049852512.1	52	Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72163	"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway"
XP_049842094.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049838197.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049864552.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049841416.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events"
XP_049839545.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049864418.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049837352.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049834508.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049844294.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049834109.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_049844692.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_049849469.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049836856.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049864241.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_049864816.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049839912.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049828275.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049848677.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049843279.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049860325.1	12	MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Biotin transport and metabolism";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate"
XP_049839506.1	7	KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_049864499.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
YP_010417158.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049845243.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049854604.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049844996.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049860627.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049840049.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049864044.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049854277.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049848153.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049836431.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_049830917.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_049851310.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049830942.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_049857427.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049840458.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049857248.1	20	Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-165159;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1	"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"Macroautophagy";"PIP3 activates AKT signaling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection"
XP_049848803.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049859240.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049858585.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049829847.1	12	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049836310.1	1	KEGG: 00290+4.2.1.33	"Valine, leucine and isoleucine biosynthesis"
XP_049859012.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049834676.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049829683.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049845426.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_049845611.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock"
XP_049841076.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049854190.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049828690.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049849036.1	11	MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;MetaCyc: PWY-6964	"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II"
XP_049853649.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049827098.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049860405.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049844687.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049829705.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049830216.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049837659.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049831581.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049834273.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049830436.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049851486.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-1622	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Rubisco shunt";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)"
XP_049846043.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049834726.1	4	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17	"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions"
XP_049833205.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049833881.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049854918.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049830181.1	32	Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167246	"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_049828655.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049854256.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_049839499.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049836762.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049853489.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049850317.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049860300.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049833452.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049846006.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-381042	"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression"
XP_049844191.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049851584.1	7	Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049844185.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049834267.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049853809.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049855232.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049853266.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_049847654.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049856215.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049835996.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049835656.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049849083.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049835995.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049832248.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_049840623.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049864445.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
YP_010417150.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049840897.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049835551.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049833689.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis"
XP_049831145.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049851027.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049830050.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
XP_049838779.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049857835.1	12	MetaCyc: PWY-7295;KEGG: 00660+4.1.3.25;KEGG: 00720+4.1.3.25;MetaCyc: PWY-5744;MetaCyc: PWY-7854;MetaCyc: PWY-5749;MetaCyc: PWY-7294;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7118;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00620+2.3.3.9	"L-arabinose degradation IV";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Itaconate degradation";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism"
XP_049857146.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049853808.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049855235.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049830187.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-532668	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049850533.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049858714.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049847190.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
XP_049827417.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049840486.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049828833.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049837094.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049832598.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049855135.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049834169.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049849966.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049827151.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049841996.1	9	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway"
XP_049847472.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049852781.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049851288.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049849617.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049827567.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049857157.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049851309.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049848617.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_049859381.1	26	Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847	"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones"
XP_049837040.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049838366.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049826890.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-428890	"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling"
XP_049827474.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049846773.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049838129.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049851301.1	4	KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049847423.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049845825.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049860275.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049827424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049833714.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049857810.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049856189.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid"
XP_049844724.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049840938.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049828799.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049855137.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049843526.1	10	KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycerol degradation to butanol";"Glycolysis"
XP_049847449.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049834914.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049832169.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837244.1	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049830399.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049855590.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049830847.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049848526.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049850276.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049831420.1	13	MetaCyc: PWY-7821;MetaCyc: PWY-7187;MetaCyc: PWY-7206;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66	"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Purine catabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism"
XP_049831416.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-204626	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Hypusine synthesis from eIF5A-lysine"
XP_049829690.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049836050.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_049845314.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049843592.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049842469.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049860481.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049849812.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling"
XP_049829787.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049844233.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049840160.1	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_049839635.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459	"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049844563.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049844140.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049827637.1	9	MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-5663	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_049862389.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852860.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049855902.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049858824.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049857083.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049860958.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049859974.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049833758.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049841531.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049833723.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_049827229.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049863788.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049828375.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049842421.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049829442.1	4	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans"
XP_049860428.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_049833329.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049832566.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049858211.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_049858243.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049829424.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049840302.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049835289.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049835634.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049858937.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049849049.1	8	Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-8950505	"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049849310.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049850705.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049839424.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049836983.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049852082.1	5	MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177	"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II"
XP_049837129.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049853041.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049859757.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049864525.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049860185.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049836990.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_049846640.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049831777.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049847184.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049850135.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049862385.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862853.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-6811436	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049848529.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049852384.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049851150.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049829971.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049844769.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049853807.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049847939.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049834582.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853597.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049861564.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049863984.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049829213.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049831470.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049840167.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049841930.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049831531.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049862867.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049843789.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049851621.1	14	Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-9634638;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049862833.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049853079.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049853478.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049840168.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049838131.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838156.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_049835394.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049829231.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049852436.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049833845.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049837148.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049856899.1	3	Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12	"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism"
XP_049845821.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049857170.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Neddylation"
XP_049845653.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049852782.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049852182.1	13	MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5	"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism"
XP_049831315.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049846648.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049862818.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049861298.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049836536.1	8	MetaCyc: PWY-5723;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;MetaCyc: PWY-1861	"Rubisco shunt";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049841770.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049858067.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049828693.1	7	MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Thiamine metabolism"
XP_049839876.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049853812.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049832687.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049857904.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049837124.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049850282.1	7	Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049852819.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049854656.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_049852443.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_049849751.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049861257.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049864330.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049838853.1	7	Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-9018519	"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression"
XP_049833076.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049858042.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049858587.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049846981.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049836590.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049830131.1	2	Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049848683.1	13	Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049862873.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049864672.1	5	KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)"
XP_049853057.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049828714.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049845108.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049852877.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049852947.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049853925.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049843573.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049846347.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_049858171.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049844684.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049827532.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049858696.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049847655.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049858726.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049846859.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049852404.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049828354.1	12	Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1	"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection"
XP_049836639.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049843510.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049844106.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049848759.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049844732.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-432040	"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049836448.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation"
YP_010417148.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049842217.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049854692.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049837028.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049853622.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049840684.1	25	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276	"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_049829346.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049849749.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049840742.1	14	Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700	"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_049860710.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049849033.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049840738.1	21	Reactome: R-HSA-5357905;Reactome: R-HSA-5684264;Reactome: R-HSA-937041;Reactome: R-HSA-9020702;Reactome: R-HSA-933543;Reactome: R-HSA-5603027;Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5603029;Reactome: R-HSA-5607764;Reactome: R-HSA-937039;Reactome: R-HSA-2871837;Reactome: R-HSA-1810476;Reactome: R-HSA-168927;Reactome: R-HSA-5602636;Reactome: R-HSA-5357956;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-1169091	"Regulation of TNFR1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKK complex recruitment mediated by RIP1";"Interleukin-1 signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downstream TCR signaling";"ER-Phagosome pathway";"IkBA variant leads to EDA-ID";"CLEC7A (Dectin-1) signaling";"IRAK1 recruits IKK complex";"FCERI mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TICAM1, RIP1-mediated IKK complex recruitment";"IKBKB deficiency causes SCID";"TNFR1-induced NFkappaB signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells"
XP_049864416.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049836578.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049854634.1	17	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-9616222;Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-1912408;Reactome: R-HSA-139915;Reactome: R-HSA-2559585;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-69231;Reactome: R-HSA-111448;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional regulation of granulopoiesis";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"Pre-NOTCH Transcription and Translation";"Activation of PUMA and translocation to mitochondria";"Oncogene Induced Senescence";"G0 and Early G1";"Oxidative Stress Induced Senescence";"Cyclin D associated events in G1";"Activation of NOXA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049855934.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049838757.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049845084.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049838410.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049838391.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049843599.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049839500.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049857731.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049853460.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218	"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_049855598.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049837711.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049864234.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049857818.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049832820.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049859443.1	10	KEGG: 04150+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499	"mTOR signaling pathway";"Human papillomavirus infection";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane"
XP_049837387.1	6	MetaCyc: PWY-6367;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_049831998.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049828759.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049860960.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049838487.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049831306.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049853504.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049836034.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049861673.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049838705.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049845713.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049834482.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049840720.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049854821.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049860790.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049854671.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049864547.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_049850755.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049860291.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049829686.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049848955.1	30	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73779	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049837694.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049862400.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049834667.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049831296.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049833306.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049857220.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049832573.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049861369.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049854655.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049827018.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049855255.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_049842596.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049859745.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049863096.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049829859.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049863221.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049836329.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049857369.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049851054.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049830753.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_049852430.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049859694.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_049834488.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049839542.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049844201.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049857300.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850475.1	10	KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_049838773.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049828168.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_049852196.1	4	KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;MetaCyc: PWY-6352	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis"
XP_049836275.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049850138.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049857098.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049864371.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049849434.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049852735.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049836995.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049837861.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049841455.1	3	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049848923.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049852343.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049834454.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049833083.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049850521.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5545483	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1"
XP_049831326.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_049834696.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_049838778.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049850017.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_049837396.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049849802.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_049862850.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_049843062.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049834756.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049844863.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049855071.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049860698.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049848834.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049830309.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049863097.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049826927.1	8	KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27	"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism"
XP_049860961.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049854506.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411	"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere"
XP_049828071.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049858213.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049839711.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049828892.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049845838.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049843259.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_049826921.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049827467.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049846098.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049839247.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049862726.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049828938.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049830884.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862691.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049841728.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_049863976.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049853564.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_049844186.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049861672.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049847658.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049830493.1	13	Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-419037	"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Anchoring fibril formation";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"ECM proteoglycans";"Collagen chain trimerization";"NCAM1 interactions"
XP_049859178.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049834743.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049846649.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049836245.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049857714.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049862579.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049863775.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049847207.1	11	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049863991.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049848699.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049852660.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049857128.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049833567.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049847879.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049839394.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049844767.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049828512.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049844189.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049853280.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049831618.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_049857095.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049851333.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049858029.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049853019.1	3	MetaCyc: PWY-1269;Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism";"Lipopolysaccharide biosynthesis"
XP_049842685.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049837138.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049858631.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_049843346.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_049832686.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049841984.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_049838713.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049849507.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049852225.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_049860688.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049862798.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049832993.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049838715.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049853417.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049838482.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_049860144.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049845098.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049849460.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049847402.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049863407.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049832574.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049830645.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors"
XP_049851115.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348	"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex"
XP_049854299.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_049853856.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049852405.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049857891.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049834671.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049829267.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049861254.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049849375.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049839906.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049835640.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049851878.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_049838863.1	6	Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73933	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)"
XP_049838695.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"PPARA activates gene expression"
XP_049830988.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049833734.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049828734.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049845203.1	5	Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049860774.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049864670.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049835981.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049848962.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_049854649.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049855686.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049827938.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_049844615.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838724.1	3	Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049835230.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049836846.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6832;KEGG: 00440+2.6.1.37;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"2-aminoethylphosphonate degradation II";"Phosphonate and phosphinate metabolism";"Peroxisomal protein import"
XP_049839780.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049853205.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_049857234.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049848241.1	10	MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism"
XP_049853255.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_049844902.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049861699.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049849086.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"ATP biosynthesis";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Photosynthesis";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049831071.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049859412.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049833044.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049849491.1	18	MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383	"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049829960.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-9018519	"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression"
XP_049849386.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6	"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation"
XP_049842417.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049863269.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_049839422.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Protein ubiquitination"
XP_049863890.1	7	Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-2559586	"Cleavage of the damaged purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049844749.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049829179.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049845657.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_049858339.1	5	Reactome: R-HSA-1234174;Reactome: R-HSA-1234158;Reactome: R-HSA-1234176;Reactome: R-HSA-8849473;Reactome: R-HSA-8951664	"Cellular response to hypoxia";"Regulation of gene expression by Hypoxia-inducible Factor";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"PTK6 Expression";"Neddylation"
XP_049827522.1	3	KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685	"Pyrimidine metabolism";"Purine metabolism";"Detoxification of Reactive Oxygen Species"
XP_049850529.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756	"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation"
XP_049841896.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5358565	"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049842657.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049850875.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049857825.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049829875.1	11	MetaCyc: PWY-6964;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6549;MetaCyc: PWY-381;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2	"Ammonia assimilation cycle II";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_049851459.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049829934.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_049855553.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049861770.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838945.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049854755.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049849098.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049860372.1	5	Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;MetaCyc: PWY-6129	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049851214.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049845670.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_049857770.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049833075.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049855101.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049856473.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049842574.1	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049849583.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049829606.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049828213.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_049848248.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049846059.1	9	MetaCyc: PWY-6839;MetaCyc: PWY-6322;KEGG: 00440+4.1.1.82;MetaCyc: PWY-5757;MetaCyc: PWY-8067;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6682;MetaCyc: PWY-7510;MetaCyc: PWY-7769	"2-aminoethylphosphonate biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis";"Methylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosalacine biosynthesis"
XP_049848673.1	11	KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-5695	"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation"
XP_049828143.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-187577	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21"
XP_049844606.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775	"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"DAG and IP3 signaling";"Ion homeostasis"
XP_049842696.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049856205.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049859380.1	26	Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629	"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation"
XP_049859759.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049861402.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049859151.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049843036.1	6	MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_049859547.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049849287.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049857314.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049857370.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049857783.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049834545.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination"
XP_049863810.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049842794.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes"
XP_049839469.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_049852992.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049845322.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_049844830.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049853481.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049851125.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749	"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated"
XP_049843034.1	6	MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis"
XP_049828678.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049832258.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049857819.1	12	Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6804756	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation"
XP_049855381.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049836312.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049828695.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049857779.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049830377.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049831744.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853549.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049862849.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_049834457.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049833695.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049848087.1	4	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049860153.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049839732.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049839540.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049857210.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049859086.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs"
XP_049861584.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049853206.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_049850001.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049834668.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049831374.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049839628.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049860442.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049841891.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853	"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes"
XP_049827428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049850004.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049846401.1	19	Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471	"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Platelet sensitization by LDL";"Chylomicron remodeling";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"LDL remodeling";"VLDL clearance";"Scavenging by Class B Receptors"
XP_049834770.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
XP_049846181.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049853524.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049835838.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_049834697.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049856044.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5620922	"Activation of SMO";"Hedgehog 'on' state";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium"
XP_049852478.1	5	Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;Reactome: R-HSA-9033500;MetaCyc: PWY-7782	"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis"
XP_049831765.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049829582.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001	"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade"
XP_049864588.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049831109.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049843049.1	5	Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532	"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)"
XP_049854483.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049852015.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049842328.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5689880	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases"
XP_049851248.1	57	Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236	"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049831975.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497	"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049827422.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049839272.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049853230.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049863983.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049838889.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049863791.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049831872.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332	"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin"
XP_049842538.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_049828386.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049827029.1	6	KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346	"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_049856880.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049857940.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049862725.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049842108.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049852863.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230	"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA"
XP_049860732.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049844971.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049856591.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049849905.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049863129.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049863211.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6798695	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Neutrophil degranulation"
XP_049833048.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049837125.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049830874.1	1	Reactome: R-HSA-1234176	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049836589.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049852772.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049835887.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049850899.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049827080.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049829308.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049840822.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049843561.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049850266.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049852661.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049837626.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_049857473.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane"
XP_049854786.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827898.1	11	MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456	"Mannitol degradation II";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation"
XP_049864524.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049843072.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049840082.1	7	MetaCyc: PWY-7818;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis"
XP_049856227.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049841735.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049848597.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049859786.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049827794.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049849096.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049849962.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_049828570.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049829323.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049845228.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049846746.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-9640463;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_049852941.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049840819.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049839390.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049837765.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049828687.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049863100.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049830610.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_049850007.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049844864.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049837280.1	33	MetaCyc: PWY-6871;MetaCyc: PWY-6333;MetaCyc: PWY-7111;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5079;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5076;KEGG: 00625+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00982+1.1.1.1;KEGG: 00071+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-1801;MetaCyc: PWY-7396;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-3162;MetaCyc: PWY-6587;MetaCyc: PWY-7798;MetaCyc: PWY-5082;MetaCyc: PWY-6313;MetaCyc: PWY-5078;MetaCyc: PWY-7118	"3-methylbutanol biosynthesis (engineered)";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to isobutanol (engineered)";"Salidroside biosynthesis";"Tyrosine metabolism";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Methane metabolism";"L-phenylalanine degradation III";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Noradrenaline and adrenaline degradation";"L-leucine degradation III";"Chloroalkane and chloroalkene degradation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Fatty acid degradation";"Ethanol oxidation";"Formaldehyde oxidation II (glutathione-dependent)";"Butanol and isobutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol II";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"alpha-Linolenic acid metabolism";"Phenylethanol biosynthesis";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol III";"Protein S-nitrosylation and denitrosylation";"L-methionine degradation III";"Serotonin degradation";"L-isoleucine degradation II";"Chitin degradation to ethanol"
XP_049864785.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_049830305.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049859242.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049850088.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049849202.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-180534	"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4"
XP_049840948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049834623.1	14	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7417	"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049851921.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049857247.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049864264.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049830763.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049836377.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049837871.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049852831.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049828358.1	12	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049842364.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049848882.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049850293.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049847387.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049859084.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_049843595.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049847521.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-202733	"VLDL clearance";"Scavenging by Class B Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Chylomicron remodeling";"Platelet sensitization by LDL";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall"
XP_049839273.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_049859193.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049831496.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049828196.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049844141.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049842888.1	9	MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049829682.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049848101.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_049829378.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_049834500.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049833066.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835483.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049850186.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049834270.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049848934.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049863792.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049857559.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049864728.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism"
XP_049855956.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049849008.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049857035.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853520.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_049842160.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049849167.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049840462.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850781.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049857147.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049827268.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436	"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049838551.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049836005.1	22	MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7053;Reactome: R-HSA-75876;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6958;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis"
XP_049850715.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049859376.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508	"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_049859993.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049827883.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049851693.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049862236.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049843087.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049841222.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_049843607.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049861180.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049835231.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049854962.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049838962.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049860446.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_049854004.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049828276.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049835877.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049830375.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049833021.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049855949.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_049854301.1	58	Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5689901;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Metalloprotease DUBs";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21"
XP_049841212.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049847557.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049861260.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049856099.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049836149.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_049864574.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049835806.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049860678.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049841651.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049849379.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049857993.1	5	Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108	"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049853515.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049835804.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049852008.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding"
XP_049836279.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_049828391.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049845521.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049850357.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049859444.1	10	KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection"
XP_049852872.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Neutrophil degranulation";"Cargo concentration in the ER"
XP_049851919.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_049848609.1	4	MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;MetaCyc: PWY-5269	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II"
XP_049849566.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism"
XP_049836404.1	5	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049862626.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049846775.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049850611.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-2559586	"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049862778.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049826988.1	8	Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Signaling by Hippo";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049838991.1	12	Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Purine metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Selenocompound metabolism";"Sulfite oxidation III"
XP_049853203.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049834490.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049831724.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049828514.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049834897.1	33	Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-69656;Reactome: R-HSA-427413	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression"
XP_049827027.1	6	KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism"
XP_049860130.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049842223.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049850703.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049863431.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049856828.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_049853190.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049844585.1	6	MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_049849291.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049864098.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049847398.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049845531.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_049864153.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049859103.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049831752.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049847457.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853	"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes"
XP_049836889.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049845735.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049840117.1	12	Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13	"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism"
XP_049845399.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049858895.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049838639.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049863974.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049845658.1	5	Reactome: R-HSA-1237112;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-9627069	"Methionine salvage pathway";"Formation of apoptosome";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity"
XP_049840818.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049851340.1	10	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-3821	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"D-galactose detoxification"
XP_049836376.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049828138.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835824.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049849689.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049828421.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049827237.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049864288.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049853880.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049863083.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049858755.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049830609.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049830221.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049849324.1	5	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_049838505.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049832182.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049834707.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049831725.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049837088.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049844545.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049850329.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049840668.1	17	KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744	"Propanoate metabolism";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Carnitine metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation"
XP_049829435.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049828849.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049839195.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049827517.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827922.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049861828.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_049830180.1	32	Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167290	"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_049828133.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049855817.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049837269.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049862715.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_049850876.1	8	Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-4661;MetaCyc: PWY-6372	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_049847807.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G"
XP_049850736.1	10	MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10	"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_049852824.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049849196.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049833438.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049830430.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_049850025.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049834448.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049838634.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049848567.1	18	KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Methane metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049861011.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049838918.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049844826.1	8	Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Regulation of the apoptosome activity"
XP_049844906.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049863986.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049828246.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049850640.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_049857903.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049839608.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049847974.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049836681.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049864648.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049839846.1	10	KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722	"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex"
XP_049854676.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049844795.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049839259.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_049859239.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049847009.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049861042.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049838145.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_049864415.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
XP_049857994.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_049849701.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049842157.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049851192.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_049834685.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049831697.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049827222.1	6	MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118	"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle"
XP_049860623.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049854067.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049846189.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844737.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_049835415.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049833428.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049863042.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049851410.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049863751.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049846557.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049844583.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin metabolism"
XP_049846229.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220	"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins"
XP_049849289.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049859361.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049848527.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049847618.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049831796.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049860847.1	24	Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-2871837	"PIP3 activates AKT signaling";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Thermogenesis";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation"
XP_049839401.1	10	MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10	"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Butanoate metabolism"
XP_049836389.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-8873719	"TBC/RABGAPs";"RAB geranylgeranylation"
XP_049859948.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_049828566.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049838643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844364.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049851205.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049849057.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049838307.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049863015.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519	"Circadian Clock";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression"
XP_049860022.1	33	Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690	"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events"
XP_049837118.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049834531.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049851798.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049848335.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049832129.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)"
XP_049857999.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049850285.1	10	Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7199;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943	"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049851057.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049845652.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049852944.1	6	KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33	"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis"
XP_049850860.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049831313.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049829773.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049864360.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049862666.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049846095.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049828151.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049864562.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049860941.1	18	Reactome: R-HSA-5693568;Reactome: R-HSA-5689901;Reactome: R-HSA-8953750;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Metalloprotease DUBs";"Transcriptional Regulation by E2F6";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation"
XP_049844772.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049830782.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_049858242.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049845473.1	6	KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049844423.1	10	MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-6842	"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II"
XP_049851670.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049833204.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049845700.1	16	KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690	"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle II (plants and fungi)"
XP_049858820.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049848265.1	2	MetaCyc: PWY-6163;KEGG: 00400+4.2.3.5	"Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_049839712.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049853281.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049836177.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling"
XP_049844464.1	57	Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154	"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin"
XP_049843999.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones"
XP_049849613.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049859558.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049830697.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049831160.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049860772.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049837308.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049838305.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049864292.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049848678.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-5389840;Reactome: R-HSA-975956;Reactome: R-HSA-5419276;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Mitochondrial translation termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049827753.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049862693.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049851374.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049850855.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049844103.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049836008.1	22	MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_049846194.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_049862819.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852779.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049826919.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049827107.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049846883.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049852821.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049840269.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
XP_049827429.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049842970.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049843761.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049843094.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049845659.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049840118.1	12	MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_049832004.1	10	KEGG: 00410+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6536;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535	"beta-Alanine metabolism";"4-aminobutanoate degradation V";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Degradation of GABA";"Propanoate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation I"
XP_049842643.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5467337	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding"
XP_049846158.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049833259.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049846728.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_049853928.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_049828184.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049861937.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049839203.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049853432.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_049863017.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Circadian Clock";"Attenuation phase";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation"
XP_049858043.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Propanoate metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049853828.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049830906.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049849982.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049837206.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049854106.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049833896.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation"
XP_049854809.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049844514.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049850338.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049837712.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049840523.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049833762.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049838304.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049850794.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049838609.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049847016.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049827084.1	15	Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-5637810;Reactome: R-HSA-9665249;Reactome: R-HSA-9665250;Reactome: R-HSA-1227986;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-9665251;Reactome: R-HSA-9665246;Reactome: R-HSA-9664565;Reactome: R-HSA-9665245;Reactome: R-HSA-9665244;Reactome: R-HSA-8863795	"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to neratinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Downregulation of ERBB2 signaling"
XP_049853861.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Arginine and proline metabolism"
XP_049839046.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049850318.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049842144.1	9	MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;MetaCyc: PWY-6142;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_049844614.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049861363.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_049836004.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7053;Reactome: R-HSA-75876;MetaCyc: PWY-7606;MetaCyc: PWY-7726	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049842534.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40	"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049850658.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258	"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL"
XP_049828393.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049862945.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049859407.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049859065.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049863061.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_049844293.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049845643.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049858906.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049854150.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049846699.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049834706.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049847228.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844446.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049847830.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258	"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL"
XP_049851681.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_049831580.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049858644.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049863979.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049829539.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049843084.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049834407.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848872.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049841980.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049856474.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049849687.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_049855126.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049856401.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049844200.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049855803.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049855637.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049847326.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049862981.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049827097.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_049864669.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829476.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049850619.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049844613.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049834546.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination"
XP_049859692.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049859555.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049848489.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049844910.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_049841676.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049835144.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049845133.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049835453.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049829597.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049835953.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049860148.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049860210.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049836082.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049839913.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049840298.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049858169.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049844516.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049846298.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049852912.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049862616.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049842964.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049849942.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049848946.1	5	Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7185;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism"
XP_049837304.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_049830285.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049864040.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049842168.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049844137.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_049836246.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)"
XP_049847212.1	4	KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247	"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids"
XP_049833728.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049833051.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049846638.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049835383.1	18	KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-5362517;Reactome: R-HSA-70895;MetaCyc: PWY-5084;Reactome: R-HSA-70268;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Glycine degradation";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Lysine catabolism";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049832702.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049852938.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_049864401.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_049841453.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis"
XP_049859987.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_049829460.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049827945.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049831599.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049833952.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_049849361.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049837452.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049864319.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049863648.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049827106.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049833072.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862824.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049850759.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049841381.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049849582.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049830129.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18	"Heme degradation";"Iron uptake and transport";"Heme degradation I";"Porphyrin and chlorophyll metabolism"
XP_049857270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049830019.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins"
XP_049827939.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_049846739.1	12	MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-6936;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-1187;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13	"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Selenocompound metabolism"
XP_049836124.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping"
XP_049834901.1	33	Reactome: R-HSA-69273;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-69231;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-69656;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-69202;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin D associated events in G1";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049864127.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049847561.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049864642.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049838252.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Neutrophil degranulation";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049829319.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049830967.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049844179.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049864080.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049844441.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049862256.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049850936.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049861370.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049853249.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049852865.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049860792.1	18	KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6638	"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III"
XP_049847666.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049827153.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049856209.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049849395.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049838135.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_049844847.1	7	Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049859914.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049862433.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847128.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049829421.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049858270.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049858312.1	8	KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817	"T cell receptor signaling pathway";"Synthesis of PG";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049849413.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-416993	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors"
XP_049846647.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049840067.1	31	MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5142;MetaCyc: PWY-8049;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-5973;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;Reactome: R-HSA-163765;MetaCyc: PWY-6113;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-7746	"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Bacterial bioluminescence";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Mycobacterial sulfolipid biosynthesis"
XP_049829395.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049834066.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049834240.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844142.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_049860843.1	24	Reactome: R-HSA-5607764;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757	"CLEC7A (Dectin-1) signaling";"Human papillomavirus infection";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"Activation of AKT2";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Thermogenesis";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Regulation of TP53 Degradation"
XP_049858088.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_049840025.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049851835.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_049841405.1	28	Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-5685942	"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)"
XP_049850921.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049858913.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049828280.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049827269.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049856722.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5871	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_049833713.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049826975.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049829645.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_049844962.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049837618.1	5	Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391	"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_049858309.1	8	Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-5269	"Synthesis of PG";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II"
XP_049844555.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049833237.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844228.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049854249.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850747.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049864121.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049864071.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049864327.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049830968.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049844270.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049860821.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049849013.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049841512.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049843703.1	10	KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5484	"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)"
XP_049841932.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049834673.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049828292.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-7765;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-6309	"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_049852566.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049828074.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049843439.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049859383.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049833354.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049859075.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049839895.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049844104.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049833427.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049832633.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049855111.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049859569.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838503.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049853532.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049837948.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049860788.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049849366.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049850514.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049836391.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049862432.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848479.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_049861512.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049862397.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049845957.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049849767.1	24	Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-165158;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1	"GPVI-mediated activation cascade";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Activation of AKT2";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway"
XP_049839757.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_049839887.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049828419.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049846944.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049848818.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049858582.1	5	MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_049839496.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049835269.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049840660.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049850843.1	17	Reactome: R-HSA-75955;Reactome: R-HSA-113418;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167243;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"T cell receptor signaling pathway";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_049830202.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049859445.1	10	KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049848570.1	6	Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2	"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine metabolism"
XP_049829972.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049828111.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049839756.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_049862740.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_049847448.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049829508.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838158.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049860272.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049863977.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049848822.1	4	KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95	"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_049845423.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049845574.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049863706.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_049832583.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049839946.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049849051.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049859562.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049853562.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_049846489.1	6	KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049859756.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049853194.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049847559.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049828158.1	13	MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9	"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate"
XP_049839558.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049858642.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049835833.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049857217.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049854328.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049860761.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736	"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors"
XP_049835657.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049859687.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049839961.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049835410.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049845648.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_049832247.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_049837240.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049837102.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049858472.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049851218.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049844105.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049857458.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049838646.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049862449.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049846096.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049849849.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_049835501.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049840990.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049826932.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049837188.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049827708.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_049834009.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis"
XP_049849621.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049857316.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049826903.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565	"RUNX2 regulates osteoblast differentiation";"Myogenesis";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049858684.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)"
XP_049856267.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-975634	"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport"
XP_049846630.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049843274.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897	"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes"
XP_049839589.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049847160.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049854939.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843731.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049850858.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_049853189.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049860844.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-354192;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920	"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Human papillomavirus infection";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"Downstream TCR signaling";"Activation of AKT2";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Thermogenesis";"VEGFR2 mediated vascular permeability"
XP_049855759.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049835561.1	9	MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation"
XP_049863391.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_049852070.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049845147.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049863781.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049844718.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049844714.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049835494.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_049846915.1	12	KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-7238	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II"
XP_049860046.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049834108.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049857906.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049852524.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049831729.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049858050.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049837953.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049854559.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049844862.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049827942.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions"
XP_049840228.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_049853305.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049834613.1	14	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism"
XP_049828571.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049832576.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049850348.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049861484.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_049837996.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049837863.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049852467.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation"
XP_049849943.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049848416.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049839085.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049852231.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_049835638.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049826992.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049833088.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049841210.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049862069.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling"
XP_049837868.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049846978.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049829780.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049848851.1	28	Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310	"G2/M DNA damage checkpoint";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway"
XP_049843600.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049856412.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049827075.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049838644.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049849042.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049843155.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049838220.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049855373.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_049852557.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630221	"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing"
XP_049836353.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049857171.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049859540.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049864760.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049828252.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049852933.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049856444.1	5	MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_049831801.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049840547.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049848434.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049847985.1	5	MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049851153.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
XP_049858195.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854126.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049839201.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049841229.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_049831712.1	13	MetaCyc: PWY-7112;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450"
XP_049862753.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049859561.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_049857922.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049844843.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049853228.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049854302.1	58	Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5689901;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253	"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Metalloprotease DUBs";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex"
XP_049843224.1	5	KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate"
XP_049855636.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049844889.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_049846228.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497	"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049857279.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049827617.1	52	Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553	"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs"
XP_049830290.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049833670.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850418.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_049848226.1	17	MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_049833152.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049860670.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837	"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases"
XP_049835451.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049852840.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049854693.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049846280.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049844199.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049837870.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049852547.1	33	Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-5619107	"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_049848353.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049848908.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049851290.1	19	KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690	"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"TCA cycle II (plants and fungi)"
XP_049862695.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049863044.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049845194.1	5	Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049848011.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049851723.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049852613.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049853672.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049857305.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049844011.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091	"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells"
XP_049862392.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848808.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049847864.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049848978.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049845139.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049854362.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049846515.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049839199.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049830693.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049863758.1	52	Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-72165;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-76066;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749	"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs"
XP_049853229.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049846032.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049851124.1	14	MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;Reactome: R-HSA-196757	"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Photorespiration ";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Metabolism of folate and pterines"
XP_049828602.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049858832.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049863955.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049835882.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049833129.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049846861.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049844972.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049849182.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049861425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049857939.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049854936.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049860021.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049835779.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049836980.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745	"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_049854771.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049841049.1	29	Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Meiotic recombination";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Dual Incision in GG-NER"
XP_049834581.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830211.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions"
XP_049844424.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049843502.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049851451.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049862436.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848664.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049856402.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324	"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049863402.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049843764.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-167162	"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape"
XP_049863953.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049852334.1	18	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;KEGG: 00970+6.1.1.1;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-379726	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aminoacyl-tRNA biosynthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Mitochondrial tRNA aminoacylation"
XP_049850211.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_049834684.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049840583.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049863101.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049838472.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism"
XP_049833911.1	4	Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049837133.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049851642.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049854248.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049835272.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049837538.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040	"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis"
XP_049835262.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049851613.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049837997.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049840602.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049856522.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720	"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis"
XP_049864701.1	8	KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism"
XP_049851105.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049826959.1	7	Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300	"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA"
XP_049861098.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049857102.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049835873.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049828262.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049849355.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049856158.1	6	Reactome: R-HSA-1855204;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368	"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_049845570.1	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049862669.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049842546.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049860399.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049850865.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_049861711.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049846863.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049833620.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049859726.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-6798695	"WNT ligand biogenesis and trafficking";"Neutrophil degranulation"
XP_049854195.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049835358.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049841852.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049828385.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049838392.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049843601.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049836164.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_049856214.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049844111.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049849855.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049834103.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049830105.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049863365.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049831488.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049840022.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049833801.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049827273.1	9	KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883	"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II"
XP_049857093.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049829841.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049862583.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049838859.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-5651801	"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049843571.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049827218.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118	"Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_049846279.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049852301.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049836360.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049850679.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049839764.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409	"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_049845725.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852040.1	8	MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;Reactome: R-HSA-1855183	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049856052.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9636467	"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Blockage of phagosome acidification"
XP_049849323.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_049835259.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049844298.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER"
XP_049851289.1	12	KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538	"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI"
XP_049849458.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049854107.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049855032.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049843345.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_049837501.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049851615.1	5	Reactome: R-HSA-9033241;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033500	"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins"
XP_049863389.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049848231.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049848755.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049857761.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049841890.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903	"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy"
XP_049842993.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049850061.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Propanoate metabolism"
XP_049843038.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_049852989.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580	"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence"
XP_049839960.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049830379.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049859940.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049864702.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism"
XP_049859395.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_049841998.1	9	KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_049847686.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049827683.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049850417.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049829106.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049854798.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049853757.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049862891.1	4	Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Neutrophil degranulation";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049864176.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049854120.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049863701.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049835139.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_049858971.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049843586.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049838989.1	12	MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278	"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Purine metabolism";"Purine metabolism";"Selenate reduction";"Selenocompound metabolism";"Sulfite oxidation III"
XP_049833461.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049827272.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52	"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism"
XP_049838944.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049837539.1	4	MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization"
XP_049857303.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049841043.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049845701.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049827242.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049836649.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049835957.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049837460.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049829643.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_049842397.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049852690.1	9	KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5	"Cysteine and methionine metabolism";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis"
XP_049847421.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049850272.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049830366.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049838943.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049828309.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_049849853.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049844784.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049862851.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_049851211.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_049864145.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049861635.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049864070.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049846507.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049857766.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049848432.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_049862533.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049844973.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049844537.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049832072.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049838604.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049857310.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848390.1	13	MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-7141	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis"
XP_049853535.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049848336.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049859783.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837478.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049849151.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_049858682.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049844793.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049833423.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049830709.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049850346.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049830270.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049842601.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049830898.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049850799.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049851990.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049851436.1	39	Reactome: R-HSA-390247;MetaCyc: PWYG-321;KEGG: 00770+2.7.8.7;MetaCyc: PWY-8012;MetaCyc: PWY-6282;Reactome: R-HSA-9033241;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-6012-1;MetaCyc: PWY-4381;MetaCyc: PWY-7388;MetaCyc: PWY-6012;MetaCyc: PWY-5147;MetaCyc: PWY-5971;KEGG: 00061+4.2.1.59+2.3.1.39+1.3.1.9+3.1.2.14;MetaCyc: PWY-5367;MetaCyc: PWY-5142;KEGG: 00780+1.1.1.100+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;Reactome: R-HSA-389887;MetaCyc: PWY-7858;MetaCyc: PWY-8047;MetaCyc: PWY-7663;KEGG: 00780+4.2.1.59;Reactome: R-HSA-2046106;Reactome: R-HSA-9033500;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-6519;MetaCyc: PWY-6289;MetaCyc: PWY-6799;MetaCyc: PWY-5994;Reactome: R-HSA-193368;KEGG: 00061+1.1.1.100+2.3.1.41+2.3.1.86	"Beta-oxidation of very long chain fatty acids";"";"Pantothenate and CoA biosynthesis";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Peroxisomal protein import";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Acyl carrier protein activation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl carrier protein metabolism";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Beta-oxidation of pristanoyl-CoA";"(5Z)-dodecenoate biosynthesis II";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"alpha-linolenic acid (ALA) metabolism";"TYSND1 cleaves peroxisomal proteins";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Petrobactin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Fatty acid biosynthesis"
XP_049831785.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049834647.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049862257.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049855331.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049833961.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049859198.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049827643.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049860281.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049846556.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049862705.1	11	Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-69205	"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription"
XP_049862982.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049863283.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049857401.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049858168.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049830418.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049856597.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049834731.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049829580.1	11	Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986	"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2"
XP_049857306.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049862448.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049830272.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049863770.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049844157.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049851106.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049848019.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049864097.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049844356.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_049849117.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049864289.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049848015.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049839277.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049829886.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049863635.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049838373.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049848255.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_049852737.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049864049.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049840531.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049844159.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049843712.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049839043.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049853842.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049862585.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110381	"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049857117.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049834406.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049856490.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049850520.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2"
XP_049843954.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049852283.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_049853042.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049860810.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049851844.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049832083.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049838834.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049837714.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049837601.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049851479.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049852346.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049844711.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049848829.1	7	KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-6471;MetaCyc: PWY-6385;MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049855602.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049863963.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049864736.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-9009391	"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling"
XP_049846045.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049843966.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049864275.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049852923.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049861700.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049845576.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049830591.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049849209.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049834335.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_049862704.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049845201.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_049857013.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049827676.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049836437.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049828308.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_049852539.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049851894.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049846637.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049851375.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751	"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity"
XP_049836764.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049831332.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_049851814.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049837412.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation"
XP_049828007.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049852160.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049834166.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049835803.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049862524.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853433.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049852995.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049833716.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049835584.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_049828416.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049860656.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049850928.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049831623.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049852339.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049853410.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291	"Neutrophil degranulation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C"
XP_049845276.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_049852918.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049844156.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049853785.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049849262.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020	"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import"
XP_049864333.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049851743.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049858108.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Collagen degradation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation"
XP_049833467.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049846240.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049845870.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_049853752.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_049843577.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049853844.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049863205.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049862656.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049840085.1	7	Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7886;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818	"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_049847801.1	30	Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-2644607;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-2565942;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-174113	"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Activation of NF-kappaB in B cells";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neddylation";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Regulation of PLK1 Activity at G2/M Transition";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049847389.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049835270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049851222.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227	"HCMV Late Events";"HCMV Early Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA"
XP_049844790.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400;Reactome: R-HSA-201681	"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway";"TCF dependent signaling in response to WNT"
XP_049834190.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858	"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity"
XP_049859787.1	57	Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176	"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049829324.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049849270.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049831147.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049860195.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049830332.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490	"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation"
XP_049835635.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049855236.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049839763.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049854984.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049827225.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049845223.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049857100.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049838199.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049838870.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049836109.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049860803.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049849052.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049837630.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049859702.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_049831192.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049864546.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_049849799.1	21	MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049845198.1	5	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049853147.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049840721.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049844230.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049845623.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_049862541.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049864390.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049841767.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049863694.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_049829315.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049828101.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049845797.1	2	Reactome: R-HSA-8875656;Reactome: R-HSA-8873719	"MET receptor recycling";"RAB geranylgeranylation"
XP_049860921.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049830179.1	32	Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex"
XP_049845690.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"LDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"VLDL clearance";"LDL remodeling";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Chylomicron assembly";"Platelet sensitization by LDL";"Chylomicron remodeling";"Clathrin-mediated endocytosis"
XP_049835267.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049859550.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049858643.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049840816.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049858653.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049836612.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049834049.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049863232.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049843082.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049842393.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049833688.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_049830687.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049852616.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049831714.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049833433.1	16	Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167238	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049850623.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822	"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_049839858.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049833283.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049837720.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049849263.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049828159.1	13	Reactome: R-HSA-196757;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3	"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"L-histidine degradation III";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_049864815.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049838561.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838848.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049863818.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049864259.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_049840718.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049842641.1	15	Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348	"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex"
XP_049836642.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049846431.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049859992.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049864394.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049864232.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848494.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_049844750.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049843035.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism"
XP_049847781.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829420.1	26	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977	"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway"
XP_049829223.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049827462.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049835866.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049859799.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049863271.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049853607.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049840075.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049864619.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049844871.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049849818.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049838433.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Degradation of the extracellular matrix";"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049848690.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_049845353.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049849607.1	18	MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism"
XP_049864814.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049847013.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049844975.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049859581.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049829059.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049839903.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049841454.1	4	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_049859752.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_049842980.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway"
XP_049826995.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-203927	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis"
XP_049853934.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049850423.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049827322.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049859404.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830288.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049827879.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049852579.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_049844616.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049836126.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049836002.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049850668.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049829838.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049858700.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049842058.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049862794.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049834577.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_049864554.1	14	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049861205.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049831782.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049839634.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex"
XP_049831716.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049842527.1	6	MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Methane metabolism";"Serine biosynthesis"
XP_049841326.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049852862.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4085377	"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Late Events";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins"
XP_049849883.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049847595.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049830276.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049859846.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049860669.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049827233.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049844873.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049863956.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049863011.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049864768.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049832127.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049854925.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049832111.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049859517.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049835901.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049847597.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049852323.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049838882.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049836036.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049864589.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049834682.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049857282.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049848730.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783	"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome"
XP_049853519.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors"
XP_049853863.1	17	MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Methane metabolism";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms"
XP_049848188.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049859462.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049837243.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049864260.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049845472.1	6	KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049860341.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049830589.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049844914.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049861236.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_049857778.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049861198.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049829239.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049829696.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049827005.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049857088.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049843578.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049856505.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049827585.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049832842.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049834530.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049839547.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
XP_049836160.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_049853294.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_049841384.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049833150.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049838508.1	40	Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-6782210	"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049839141.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049858064.1	11	Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis"
XP_049862889.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"PKA activation"
XP_049827591.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049862013.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_049857762.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049864039.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049840713.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049862255.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049831857.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049828176.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049837665.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850275.1	5	Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-446388	"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_049831807.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049863354.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049832604.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049833771.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049860279.1	10	MetaCyc: PWY-7510;MetaCyc: PWY-7769;MetaCyc: PWY-7419;MetaCyc: PWY-6682;KEGG: 00998+5.4.2.9;MetaCyc: PWY-5757;MetaCyc: PWY-8067;KEGG: 00440+5.4.2.9;MetaCyc: PWY-6322;MetaCyc: PWY-6839	"Rhizocticin A and B biosynthesis";"Phosalacine biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Dehydrophos biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Fosfomycin biosynthesis";"Methylphosphonate biosynthesis";"Phosphonate and phosphinate metabolism";"Phosphinothricin tripeptide biosynthesis";"2-aminoethylphosphonate biosynthesis"
XP_049861025.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049858990.1	29	Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5358565	"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049827110.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049862553.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049864168.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049832672.1	11	KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206;MetaCyc: PWY-7821;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9	"Pyrimidine metabolism";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
XP_049828643.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854	"HCMV Late Events";"HCMV Early Events";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly"
XP_049828194.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049853441.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049857082.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049853201.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049861160.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049853658.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049847911.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049851713.1	10	MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886	"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)"
XP_049846945.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049849189.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049849427.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049851013.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174154	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin"
XP_049858555.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049830302.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-5873	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_049863988.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049836051.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_049854133.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_049854770.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049856908.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049830090.1	8	KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-5154;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5;Reactome: R-HSA-70635	"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Urea cycle"
XP_049832195.1	20	MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7210;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7222;Reactome: R-HSA-499943;Reactome: R-HSA-380320;MetaCyc: PWY-7227	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_049842361.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049833978.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049854152.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049858590.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049830495.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049839233.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049854298.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049837759.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049834554.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_049832991.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049840494.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049851358.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049844336.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_049840556.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_049859629.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_049850646.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049853827.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049853706.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049858415.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049849408.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049859195.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049842183.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL"
XP_049830485.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049850834.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049841126.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049861356.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_049854864.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049827795.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049852209.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049853669.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049851648.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-5649702;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049851959.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049844913.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049861670.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049864451.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049864498.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829930.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049863274.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049862434.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049850410.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049858214.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049862936.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-6798695	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Neutrophil degranulation"
XP_049861990.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049829422.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049848018.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049838517.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_049831783.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049833687.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_049851162.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049852535.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049833216.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049850725.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049848490.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049859251.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049856212.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049859732.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049860846.1	24	Reactome: R-HSA-5218920;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-392451	"VEGFR2 mediated vascular permeability";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"GPVI-mediated activation cascade";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Activation of AKT2";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Human papillomavirus infection";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Integrin signaling";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma"
XP_049861571.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049864384.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049827211.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049837843.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049847971.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049863696.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049861797.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049832031.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049860731.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation"
XP_049838906.1	42	Reactome: R-HSA-3214842;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-5250924	"HDMs demethylate histones";"Meiotic synapsis";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"HCMV Late Events";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression"
XP_049854624.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049830761.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049853414.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_049837241.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049840577.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049857065.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049861111.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049831848.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833621.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049828417.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049863997.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049862940.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049829928.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049859792.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_049830786.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049843371.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049854009.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049845724.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049858040.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049835980.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049854278.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049852158.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049850612.1	7	Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-2559586	"Cleavage of the damaged purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049861250.1	7	MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-4302	"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Complex I biogenesis";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)"
XP_049863089.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049851199.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049835778.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049827315.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049858927.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049860384.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049829276.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049863362.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049853463.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049830574.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049849020.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049855234.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049864466.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049850227.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049848343.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_049851657.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049861771.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049863928.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism"
XP_049847442.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049854358.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049829797.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049860533.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_049862422.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852511.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049841463.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049861398.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828079.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049864359.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049830365.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049857379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848154.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049837038.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049834828.1	7	Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049861059.1	7	MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-2029485	"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis"
XP_049829322.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049861630.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049851048.1	12	Reactome: R-HSA-3322077;MetaCyc: PWY-6527;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9	"Glycogen synthesis";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_049859691.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049844534.1	7	Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238	"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Starch degradation V";"Glycogen degradation II";"Starch degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II"
XP_049840604.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_049836480.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_049864165.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049834689.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049833126.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049828740.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049854599.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_049853413.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049837666.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828272.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049831651.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_049850486.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049840237.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049827023.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049845474.1	6	KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049833466.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049842092.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049850006.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049841324.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049845857.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049832639.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_049846201.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049835174.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049839202.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049863253.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049844184.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049860194.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049862719.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049831754.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049838793.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049847395.1	6	Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622	"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_049860443.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049850287.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049858632.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049862386.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830030.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049839418.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049831781.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049847913.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049847619.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049834266.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049858176.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049843608.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049829317.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049859791.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049856471.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828112.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835888.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049830053.1	9	Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69202	"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition"
XP_049863891.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine"
XP_049844220.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049861834.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049859365.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049858462.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_049850330.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049848429.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049833841.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049864738.1	24	Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-500657	"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G-protein activation";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors"
XP_049833410.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism"
XP_049829224.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049861258.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049847440.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049847859.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
XP_049835785.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049830420.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049829212.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049863779.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049863606.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049853574.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049830926.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049859342.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_049852310.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049845307.1	15	Reactome: R-HSA-9665244;Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9665246;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9652282;Reactome: R-HSA-1227986;Reactome: R-HSA-9665250;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233	"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Drug-mediated inhibition of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab"
XP_049859534.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049838195.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049850708.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049858474.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049827466.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049830029.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049862869.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049834543.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_049839420.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049859469.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049840513.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049846236.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049828573.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049851338.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049862578.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049850898.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049846042.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049835739.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049857308.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049862349.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049834271.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049843262.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_049833847.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049845195.1	5	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling"
XP_049835382.1	18	KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-204174;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-6783984;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;MetaCyc: PWY-5084	"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Pyruvate metabolism";"Lysine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Glycine degradation";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049853819.1	8	Reactome: R-HSA-373080;Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-4608870;Reactome: R-HSA-5099900	"Class B/2 (Secretin family receptors)";"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"WNT5A-dependent internalization of FZD4"
XP_049831575.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049852063.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049827636.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"Folate biosynthesis"
XP_049839048.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049838719.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049862773.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836592.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049832412.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049853143.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049851816.1	14	KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661	"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Folate polyglutamylation";"Photorespiration ";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Folate transformations I";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I"
XP_049827016.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049857285.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_049863021.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049844195.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049838601.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049856513.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
XP_049855785.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_049855330.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835856.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049840830.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828928.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835641.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049842573.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_049840087.1	7	MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-7886	"Choline biosynthesis I";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_049842093.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049837459.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049856036.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049848771.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049858367.1	7	Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61	"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_049850369.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848491.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex"
XP_049852090.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_049862411.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049859571.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838435.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_049863970.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049841187.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049850841.1	6	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)"
XP_049862405.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049828772.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_049851948.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049850341.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049854575.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049851353.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049838936.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593	"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity"
XP_049837265.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049841858.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049840722.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049851535.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833394.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049834426.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049851576.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049855953.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049853188.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049833287.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049835461.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_049835903.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049848481.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049849909.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049862646.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049847840.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049858912.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049844554.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049845111.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049847497.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049858167.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049852260.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049851226.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054	"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA"
XP_049848981.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049855094.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049859190.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049830577.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049857482.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049827602.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049828277.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049836044.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049835916.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049848342.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049852705.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049841962.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049830929.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_049855112.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049840004.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049837458.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation"
XP_049852584.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049846373.1	8	KEGG: 00220+6.3.4.5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-5154;MetaCyc: PWY-7400;MetaCyc: PWY-4984	"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle"
XP_049830268.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049831922.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-70370;Reactome: R-HSA-5609977	"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_049829170.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049838739.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049863351.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049857101.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049843786.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049830620.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049846224.1	7	MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049852072.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049827264.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_049852890.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049852785.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049837312.1	4	Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049863700.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049833718.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049855475.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049828251.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049864522.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049827471.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049864444.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_049852823.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049838775.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049837145.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049835463.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049852843.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049827293.1	12	MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049863809.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049845752.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049851902.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049838414.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049864391.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049854756.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049835390.1	6	Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001	"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade"
XP_049843852.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049846299.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049845755.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049851281.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049862707.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852704.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049837681.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049834907.1	4	Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020	"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import"
XP_049845131.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049827979.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049831492.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049846176.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049827200.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049861338.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049856845.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_049855087.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049854134.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_049831691.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049850452.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049855469.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049842620.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049841429.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049851132.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049835808.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049844725.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049838994.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932	"Selenocompound metabolism";"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Monobactam biosynthesis";"Selenate reduction"
XP_049830016.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049841768.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049837683.1	15	Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression"
XP_049851965.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505	"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049856238.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_049849647.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049850896.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049827099.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049860367.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049852780.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049854240.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049838119.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
XP_049843086.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049830767.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049855668.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_049864470.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049842182.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL"
XP_049835784.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049828558.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049863920.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_049847685.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049848422.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049836767.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043	"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events"
XP_049846976.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049858036.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-375276	"G alpha (s) signalling events";"Peptide ligand-binding receptors"
XP_049864227.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049860614.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_049864178.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049839208.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049847892.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049845615.1	11	Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-381340;Reactome: R-HSA-2151201	"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049863786.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049829094.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049852344.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049863519.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049857235.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049863217.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049848729.1	7	KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625	"Glycerophospholipid metabolism";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_049861208.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230	"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA"
XP_049849294.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs"
XP_049862581.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049851487.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049831259.1	10	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_049862492.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049859718.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
YP_010417152.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049828709.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_049858823.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-5689880	"Methylation";"Ub-specific processing proteases"
XP_049844579.1	6	Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987	"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049852841.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049834368.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049843633.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049841731.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_049835813.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049856713.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049853038.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049859891.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049841765.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049857317.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049849694.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049834191.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049861420.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852921.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049835468.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049838628.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049860452.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049831506.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049846860.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049838390.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049860962.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049844576.1	6	KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_049863892.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049846738.1	12	MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309	"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_049845282.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049828075.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049853931.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_049858188.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049829885.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049858182.1	8	KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_049844268.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049862450.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049838309.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049831878.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049841990.1	17	Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-1834949;Reactome: R-HSA-5693548	"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Sensing of DNA Double Strand Breaks"
XP_049831104.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049860383.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844752.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049856448.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049862678.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049844232.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049846697.1	6	KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978	"Galactose metabolism";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia"
XP_049846516.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049846239.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049840580.1	7	MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351	"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049860535.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049832112.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049842043.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049828310.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_049837499.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049863802.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049864549.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex"
XP_049862180.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049852170.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941	"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses"
XP_049833127.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049843099.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049841762.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049845004.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049831708.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_049860174.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049835278.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049849902.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049838746.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049836180.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497	"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049829541.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049850636.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049830877.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852853.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049849570.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049864037.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049856981.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_049864261.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049828654.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049829545.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049864443.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049852647.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049855752.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049852492.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049833880.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049861999.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049857155.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049861693.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049840685.1	25	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878	"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport"
XP_049839112.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049857594.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6	"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation"
XP_049861217.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049836033.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049848365.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049832482.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049830417.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049828307.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-446199;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33	"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_049856798.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_049864262.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049829478.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049831790.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049834218.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049862468.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049833615.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049851989.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049847241.1	19	MetaCyc: PWY-5537;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-163765;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392	"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II"
XP_049834912.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049851806.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049836756.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049861097.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049853487.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049829305.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049839655.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049842339.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049842752.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion"
XP_049828415.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049851832.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049839377.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_049835828.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049862232.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049862406.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049856480.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049839777.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049845720.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049850255.1	9	Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_049827832.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049840996.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049848620.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_049827263.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Methylation"
XP_049858175.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049859963.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844553.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049845144.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049832671.1	11	MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-7821	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis"
XP_049859073.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049846287.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-389960	"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049862465.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049842107.1	13	KEGG: 00720+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-5392	"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II"
XP_049859781.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049846692.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_049856999.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049831645.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-69231	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1"
XP_049856230.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_049853183.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049860386.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049854608.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049864157.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838937.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519	"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression"
XP_049838861.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73930	"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_049831743.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835476.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049862390.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852703.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049835346.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049852097.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049836842.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049856477.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049845745.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_049861018.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_049843559.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049843014.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049858092.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria"
XP_049829739.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049862737.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049852993.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049859530.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049853593.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049844443.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049827003.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049857560.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049832176.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049831400.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049861367.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049835831.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049844799.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049864341.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049831852.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049851462.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049847229.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049827516.1	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39	"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis"
XP_049850268.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_049829878.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049860930.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_049854270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049859722.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049838431.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049856061.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049862398.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049850783.1	11	KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Starch and sucrose metabolism"
XP_049850473.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049851647.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049862768.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049840566.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049863111.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049853722.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049841746.1	4	Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049852157.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049851217.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049831774.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049845137.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049830185.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049859538.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_049838745.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049844974.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049850544.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049835222.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049853725.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049837604.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049859548.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049852192.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER"
XP_049862384.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830283.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression"
XP_049846078.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_049863412.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049850387.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049839962.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049853839.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049859020.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049849630.1	20	Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-110314	"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049843582.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049835979.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978	"Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production"
XP_049853495.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049836407.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_049856596.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049864233.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049831711.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049844581.1	6	KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_049860438.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049833698.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049857991.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_049862176.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049860083.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_049843637.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049830024.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_049862675.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833143.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049848804.1	14	KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-2161;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1	"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"Folate transformations I";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Methane metabolism"
XP_049846064.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049831319.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049858335.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1221632	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Meiotic synapsis"
XP_049856507.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049830694.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049828611.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049851808.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_049830269.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049832595.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049835792.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-162699	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose"
XP_049850241.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049843597.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049859890.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_049861088.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049829615.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049839992.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049855020.1	6	KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049848972.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049849888.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049850089.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049846747.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_049835639.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857398.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049863010.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695	"Attenuation phase";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049837674.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3232142	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins"
XP_049848213.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_049836162.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_049836784.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_049837047.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049844940.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049857815.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049860561.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775	"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis"
XP_049851560.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049842218.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049830463.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049832203.1	20	MetaCyc: PWY-7205;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7198;Reactome: R-HSA-499943;Reactome: R-HSA-380320;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197	"CMP phosphorylation";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_049853678.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049850751.1	18	MetaCyc: PWY-7205;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_049856608.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049838382.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049842423.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_049857776.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049826996.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049831588.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049844136.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049850981.1	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
XP_049854268.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049862696.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049846028.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788	"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling"
XP_049850879.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049862246.1	11	Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082	"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression"
XP_049849205.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049861633.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_049858620.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_049842599.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049845703.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049826923.1	8	MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation"
XP_049828305.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049861383.1	7	Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049827748.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049852403.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049826944.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049858072.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049838651.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049830106.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049854810.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049833123.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049858944.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049853576.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049834688.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049830210.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633	"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049840820.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049850352.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049831858.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049830881.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847915.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049847876.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049850697.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710	"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy"
XP_049844143.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049828569.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049845105.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049849479.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049837029.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049844918.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049848874.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049855632.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049864123.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049836086.1	1	Reactome: R-HSA-5673001	"RAF/MAP kinase cascade"
XP_049859468.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9615017	"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_049833361.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049841228.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_049835275.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049835490.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6798695;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Neutrophil degranulation";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049855954.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049841733.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049832444.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling"
XP_049840110.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049841517.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_049863142.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_049864192.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049839477.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049851900.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049857921.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049858327.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-2559586	"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence"
XP_049856049.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-182218	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation"
XP_049856835.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049861145.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049862929.1	3	Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117	"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis"
XP_049840632.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049850586.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049839329.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049860604.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049848229.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049859721.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system"
XP_049850648.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049832557.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049863655.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_049844351.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-69205;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis"
XP_049838384.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy"
XP_049853518.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors"
XP_049848924.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049828567.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049864465.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049850716.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049857622.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049852305.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_049842398.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049851170.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049858457.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049833121.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049833374.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049861158.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049838163.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049848571.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Methane metabolism"
XP_049836084.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049862870.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049859755.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049863210.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_049848592.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167243	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery"
XP_049827439.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049851929.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049856494.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049844334.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_049859122.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049864293.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049844685.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049853721.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049833975.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049854884.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression"
XP_049828293.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-7717	"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_049844922.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_049827791.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049831038.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_049850828.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049849084.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049829821.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049852410.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049835564.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049838774.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049848816.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049849470.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049856475.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847585.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049839145.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049828265.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049845858.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049828429.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_049847944.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049829583.1	11	Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642	"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling"
XP_049844282.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_049829857.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049847614.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049853833.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_049834572.1	6	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)"
XP_049860488.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049859250.1	2	KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5	"Fructose and mannose metabolism";"Pentose and glucuronate interconversions"
XP_049835902.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049861439.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049851942.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8	"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049851868.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_049855814.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049841784.1	9	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049829820.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere"
XP_049848465.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049850426.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178	"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049851963.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049856716.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049853997.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049847549.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049842966.1	9	MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)"
XP_049845097.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049831960.1	52	Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-72165;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-6782210	"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049843100.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1"
XP_049859717.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049833052.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049841226.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_049843102.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion"
XP_049832410.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049857483.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049828526.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049835083.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049862219.1	6	MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049829756.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049856755.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049837899.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049843098.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1"
XP_049831322.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049838347.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049852847.1	10	Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049828539.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049852974.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049846546.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049849152.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10	"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_049844144.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049845756.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049861064.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049855793.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091	"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells"
XP_049860233.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049829819.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_049842795.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_049862348.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049831859.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049838914.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049850136.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049853503.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049848115.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_049837623.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049834292.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_049864717.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049829211.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049837037.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049838374.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049836326.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049864069.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049860889.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049827796.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049848760.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049829745.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049829228.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049830174.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049841095.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049841096.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049837389.1	6	MetaCyc: PWY-6367;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95	"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism"
XP_049838201.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049833362.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-8849471	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_049847914.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049860142.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049858774.1	6	MetaCyc: PWY-7286;Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049828513.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049843017.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049837754.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049827625.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049848458.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049841889.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243	"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049838862.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73933	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)"
XP_049849108.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049859973.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049841286.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049848949.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049862832.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049832107.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_049837250.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease"
XP_049851377.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049857166.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049853854.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049834808.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049856709.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049829710.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049846031.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049837661.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049829873.1	11	KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964	"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II"
XP_049835814.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049859860.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049857116.1	17	Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-174411	"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere"
XP_049840306.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049833731.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049860809.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049859573.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049830710.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049861429.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861403.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049851889.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_049832178.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837846.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049857075.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049849368.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049860621.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049857889.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049842965.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049832501.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049856048.1	8	Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9636467	"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Blockage of phagosome acidification"
XP_049831582.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049855904.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049838569.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_049841047.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Formation of Incision Complex in GG-NER"
XP_049830347.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049848561.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113	"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049833309.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5607761	"Neddylation";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049831173.1	10	Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23	"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation"
XP_049861949.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049845644.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049832056.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049859537.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049863854.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049860994.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049837876.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049829475.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049858611.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049842492.1	2	KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_049863762.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049849266.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049840627.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049864808.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049827109.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049844284.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049838394.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049850721.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049835934.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049855958.1	6	Reactome: R-HSA-1483148;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668	"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I"
XP_049844715.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049858896.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049864181.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049841464.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049831447.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857772.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049838748.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_049857403.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049843565.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049846395.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049846196.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049842056.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049858116.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049864042.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049839476.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049830307.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049858589.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049864604.1	4	MetaCyc: PWY-6823;Reactome: R-HSA-947581;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis"
XP_049857718.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049844100.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049845277.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation"
XP_049837816.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049837036.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049864787.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049838917.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049839440.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049860545.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049842228.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049829966.1	13	Reactome: R-HSA-156590;MetaCyc: PWY-7112;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370	"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)"
XP_049848463.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049851895.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049850009.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049857432.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049851818.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_049829761.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049843631.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049836751.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049850026.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049853847.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049838389.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049834830.1	7	Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049839966.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049854274.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829685.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049827406.1	7	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
XP_049829803.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049856568.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049844037.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049827156.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049830104.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848604.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_049856066.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049846601.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049861358.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049837141.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049857713.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049831698.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_049830363.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049852233.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049858616.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049839755.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049835776.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049851431.1	6	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049838208.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049840165.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049848747.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049829396.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049850199.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049861119.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049827205.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049859403.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827341.1	2	Reactome: R-HSA-210747;Reactome: R-HSA-210745	"Regulation of gene expression in early pancreatic precursor cells";"Regulation of gene expression in beta cells"
XP_049853637.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049840193.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049862677.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049851145.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049860943.1	18	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5689901;Reactome: R-HSA-8953750;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Metalloprotease DUBs";"Transcriptional Regulation by E2F6";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049844114.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049841225.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049852139.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049834534.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_049846220.1	5	Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-6798695	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation"
XP_049835542.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049836815.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049857568.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049856279.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049830702.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049863144.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049837874.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049851169.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049855027.1	6	KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049852240.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049848158.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049856481.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857364.1	11	Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-6811436	"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049864125.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049828942.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049830219.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049837934.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049853187.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049831794.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049837922.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049860996.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_049843104.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049843065.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049858271.1	7	Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315	"Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol"
XP_049844580.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoic acid metabolism"
XP_049862848.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation"
XP_049849100.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049850425.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049839822.1	18	Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922	"Synthesis of PA";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PI"
XP_049837856.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049858614.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049851520.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_049850200.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049854791.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049840628.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049844305.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049838333.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_049837619.1	5	Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049859072.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049864294.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049832409.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049838930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049858324.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049836917.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_049860453.1	2	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_049859802.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049856479.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049853144.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049861499.1	29	Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776	"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape"
XP_049854238.1	11	MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_049843500.1	12	Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-73762	"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation"
XP_049842759.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049828893.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049834966.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049855834.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine metabolism"
XP_049851669.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049847816.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049846721.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049846305.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049863090.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049863973.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049842141.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049862217.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism"
XP_049850300.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049850350.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_049828084.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049833039.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049862759.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167242	"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049862190.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049830621.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049836159.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase"
XP_049836370.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049861212.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049835894.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049848552.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049847450.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049849123.1	56	Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764	"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling"
XP_049838781.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049855816.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049846518.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049852713.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049843831.1	19	Reactome: R-HSA-8964616;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-428543;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-2029482	"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"Inactivation of CDC42 and RAC1";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"EGFR downregulation";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation"
XP_049828557.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854812.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834584.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_049848562.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049860920.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_049848572.1	11	MetaCyc: PWY-7524;MetaCyc: PWY-7560;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6174;MetaCyc: PWY-6383;MetaCyc: PWY-922;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-6859	"Mevalonate pathway III (archaea)";"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway I";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis"
XP_049832986.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_049853446.1	40	Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749	"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs"
XP_049864412.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_049838161.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049850254.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049848780.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049850811.1	7	Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049835940.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049864248.1	12	KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1	"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Methane metabolism";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis"
XP_049828359.1	12	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049844559.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049829481.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049850090.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049837915.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049830330.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049863656.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049830506.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation"
XP_049849884.1	30	Reactome: R-HSA-2564830;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Cytosolic iron-sulfur cluster assembly";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049857812.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049861213.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049853680.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049840084.1	7	MetaCyc: PWY-7886;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7818;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Glycerophospholipid metabolism"
XP_049863981.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049844266.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854068.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin"
XP_049831871.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049830623.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049855957.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Synthesis of PA";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II"
XP_049860663.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_049864065.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049849065.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049864813.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049848942.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049828371.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049861129.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049848585.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049849260.1	7	MetaCyc: PWY-6969;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-7118	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Chitin degradation to ethanol"
XP_049849149.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_049832173.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049862670.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049830897.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049832764.1	13	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism"
XP_049841771.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049862258.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049831769.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049828069.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049861382.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_049835954.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation"
XP_049840023.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049864151.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049853081.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049836070.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049863073.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049830329.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049857979.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_049856062.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049828420.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049852077.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049827949.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049864663.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834288.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_049835529.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049864786.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_049849563.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049847515.1	4	MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049853528.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049863141.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_049854005.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049846941.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049857372.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049863959.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049828715.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049835782.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049861400.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049861270.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049864478.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049837625.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_049850750.1	18	MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7224	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_049845475.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism"
XP_049836544.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049829251.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827539.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_049854237.1	11	KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049842221.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049862415.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049833611.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049844550.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049830695.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049839206.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049863923.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049859736.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_049849971.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_049856523.1	5	Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305	"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D"
XP_049854407.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049839144.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049843762.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049830764.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049854006.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049863403.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049842184.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695	"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation"
XP_049856726.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049839959.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049859315.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_049838280.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049840460.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049830886.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862829.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049851909.1	7	Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)"
XP_049838033.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
YP_010417151.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049847104.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049847579.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049854481.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049854927.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049851193.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049861498.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049851283.1	1	Reactome: R-HSA-6803205	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049859054.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049854474.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049862409.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836749.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049847251.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049844260.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049830134.1	2	Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049836967.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049849463.1	3	Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-8936459	"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049829804.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049841520.1	5	KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68	"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_049839956.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049843172.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_049844036.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049863207.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049856234.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_049858617.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049848596.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049828250.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049844778.1	12	KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Macroautophagy";"Human cytomegalovirus infection";"mTOR signaling pathway";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway"
XP_049859050.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049860487.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_049851265.1	5	MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_049862922.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Neutrophil degranulation";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_049862172.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049848970.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049831612.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049828258.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049831439.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049830614.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049859795.1	4	KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049842563.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_049860188.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049836445.1	4	MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049844879.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049847379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049837032.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049844004.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
XP_049857890.1	5	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation"
XP_049852259.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049842001.1	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049844219.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049828664.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049829517.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049863958.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049844723.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049846295.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049862689.1	17	MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-5695;MetaCyc: PWY-7179;MetaCyc: PWY-6644	"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis"
XP_049832408.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049835895.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049831800.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049849271.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049834214.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049833901.1	182	Reactome: R-HSA-5357956;Reactome: R-HSA-6807004;Reactome: R-HSA-2173796;Reactome: R-HSA-5696394;Reactome: R-HSA-72764;Reactome: R-HSA-174048;Reactome: R-HSA-5685942;Reactome: R-HSA-5607761;Reactome: R-HSA-937039;Reactome: R-HSA-8948747;Reactome: R-HSA-72706;Reactome: R-HSA-9014325;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-72702;Reactome: R-HSA-1253288;Reactome: R-HSA-9633012;Reactome: R-HSA-8863795;Reactome: R-HSA-1295596;Reactome: R-HSA-2122948;Reactome: R-HSA-1358803;Reactome: R-HSA-5668541;Reactome: R-HSA-110320;Reactome: R-HSA-72649;Reactome: R-HSA-975110;Reactome: R-HSA-975144;Reactome: R-HSA-400253;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-2559580;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5358346;Reactome: R-HSA-2672351;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-6782210;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-110312;Reactome: R-HSA-977225;Reactome: R-HSA-69541;Reactome: R-HSA-8948751;Reactome: R-HSA-2644606;Reactome: R-HSA-349425;Reactome: R-HSA-201681;Reactome: R-HSA-168638;Reactome: R-HSA-175474;Reactome: R-HSA-72689;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-9637628;Reactome: R-HSA-162588;Reactome: R-HSA-72695;Reactome: R-HSA-2559585;Reactome: R-HSA-2894862;Reactome: R-HSA-450408;Reactome: R-HSA-4641263;Reactome: R-HSA-975957;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-2979096;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5654727;Reactome: R-HSA-1169408;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-937041;Reactome: R-HSA-6804756;Reactome: R-HSA-5689877;Reactome: R-HSA-69601;Reactome: R-HSA-179409;Reactome: R-HSA-8866652;Reactome: R-HSA-532668;Reactome: R-HSA-2871837;Reactome: R-HSA-6781827;Reactome: R-HSA-5362768;Reactome: R-HSA-5693565;Reactome: R-HSA-8876493;Reactome: R-HSA-6804757;Reactome: R-HSA-8852276;Reactome: R-HSA-5654732;Reactome: R-HSA-937072;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-975163;Reactome: R-HSA-5205685;Reactome: R-HSA-2565942;Reactome: R-HSA-5357905;Reactome: R-HSA-2173788;Reactome: R-HSA-901032;Reactome: R-HSA-182971;Reactome: R-HSA-3785653;Reactome: R-HSA-9013973;Reactome: R-HSA-917937;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9636383;Reactome: R-HSA-1236382;Reactome: R-HSA-4641258;Reactome: R-HSA-445989;Reactome: R-HSA-3134975;Reactome: R-HSA-174184;Reactome: R-HSA-8875360;Reactome: R-HSA-3322077;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5675482;Reactome: R-HSA-937042;Reactome: R-HSA-9615710;Reactome: R-HSA-5693607;Reactome: R-HSA-195253;Reactome: R-HSA-6791226;Reactome: R-HSA-5658442;Reactome: R-HSA-1799339;Reactome: R-HSA-209543;Reactome: R-HSA-5675221;Reactome: R-HSA-9604323;Reactome: R-HSA-6804760;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-9645460;Reactome: R-HSA-2173795;Reactome: R-HSA-68949;Reactome: R-HSA-192823;Reactome: R-HSA-917729;Reactome: R-HSA-8866654;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-5689896;Reactome: R-HSA-2173791;Reactome: R-HSA-1169091;Reactome: R-HSA-912631;Reactome: R-HSA-5654733;Reactome: R-HSA-8849469;Reactome: R-HSA-9033241;Reactome: R-HSA-5656169;Reactome: R-HSA-4641257;Reactome: R-HSA-69231;Reactome: R-HSA-2408557;Reactome: R-HSA-205043;Reactome: R-HSA-5689880;Reactome: R-HSA-5655862;Reactome: R-HSA-8856825;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-2691232;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-156827;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-168927;Reactome: R-HSA-936440;Reactome: R-HSA-450302;Reactome: R-HSA-5654726;Reactome: R-HSA-382556;Reactome: R-HSA-168928;Reactome: R-HSA-174490;Reactome: R-HSA-110314;Reactome: R-HSA-8856828;Reactome: R-HSA-2559582;Reactome: R-HSA-174113;Reactome: R-HSA-209560;Reactome: R-HSA-9013507;Reactome: R-HSA-450321;Reactome: R-HSA-5684264;Reactome: R-HSA-936964	"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of MET activity";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"DNA Damage Recognition in GG-NER";"Eukaryotic Translation Termination";"APC/C:Cdc20 mediated degradation of Cyclin B";"HDR through Homologous Recombination (HRR)";"Dectin-1 mediated noncanonical NF-kB signaling";"IRAK1 recruits IKK complex";"Regulation of PTEN localization";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TICAM1,TRAF6-dependent induction of TAK1 complex";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Ribosomal scanning and start codon recognition";"Downregulation of ERBB4 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Downregulation of ERBB2 signaling";"Spry regulation of FGF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Downregulation of ERBB2:ERBB3 signaling";"TNFR2 non-canonical NF-kB pathway";"Translesion Synthesis by POLH";"Translation initiation complex formation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Circadian Clock";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Oxidative Stress Induced Senescence";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Hedgehog ligand biogenesis";"Stimuli-sensing channels";"ER-Phagosome pathway";"UCH proteinases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Aggrephagy";"Chaperone Mediated Autophagy";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"Translesion synthesis by REV1";"Amyloid fiber formation";"Stabilization of p53";"Regulation of PTEN stability and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Autodegradation of the E3 ubiquitin ligase COP1";"TCF dependent signaling in response to WNT";"NOD1/2 Signaling Pathway";"Assembly Of The HIV Virion";"Formation of a pool of free 40S subunits";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Modulation by Mtb of host immune system";"Budding and maturation of HIV virion";"Formation of the ternary complex, and subsequently, the 43S complex";"Oncogene Induced Senescence";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR2 signaling";"ISG15 antiviral mechanism";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"IKK complex recruitment mediated by RIP1";"Regulation of TP53 Activity through Phosphorylation";"Josephin domain DUBs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC-Cdc20 mediated degradation of Nek2A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FCERI mediated NF-kB activation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of TP53 Degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR3 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TNFR1 signaling";"Downregulation of TGF-beta receptor signaling";"ER Quality Control Compartment (ERQC)";"EGFR downregulation";"Myoclonic epilepsy of Lafora";"TICAM1-dependent activation of IRF3/IRF7";"Iron uptake and transport";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Prevention of phagosomal-lysosomal fusion";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of DVL";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of innate immune responses to cytosolic DNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"InlB-mediated entry of Listeria monocytogenes into host cell";"Glycogen synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Regulation of necroptotic cell death";"IRAK2 mediated activation of TAK1 complex";"Late endosomal microautophagy";"Processing of DNA double-strand break ends";"Degradation of beta-catenin by the destruction complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of RAS by GAPs";"SRP-dependent cotranslational protein targeting to membrane";"p75NTR recruits signalling complexes";"Negative regulation of MAPK pathway";"Negative regulation of NOTCH4 signaling";"Regulation of TP53 Activity through Methylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Alpha-protein kinase 1 signaling pathway";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Orc1 removal from chromatin";"Viral mRNA Translation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"Ovarian tumor domain proteases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Activation of NF-kappaB in B cells";"Regulation of signaling by CBL";"Negative regulation of FGFR4 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Peroxisomal protein import";"Termination of translesion DNA synthesis";"Degradation of AXIN";"Cyclin D associated events in G1";"Selenocysteine synthesis";"NRIF signals cell death from the nucleus";"Ub-specific processing proteases";"Translesion synthesis by POLK";"Cargo recognition for clathrin-mediated endocytosis";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"L13a-mediated translational silencing of Ceruloplasmin expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"TICAM1, RIP1-mediated IKK complex recruitment";"Negative regulators of DDX58/IFIH1 signaling";"activated TAK1 mediates p38 MAPK activation";"Negative regulation of FGFR1 signaling";"ABC-family proteins mediated transport";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Membrane binding and targetting of GAG proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Clathrin-mediated endocytosis";"Senescence-Associated Secretory Phenotype (SASP)";"SCF-beta-TrCP mediated degradation of Emi1";"NF-kB is activated and signals survival";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049844498.1	10	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"RSK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection"
XP_049851376.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049855792.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049864102.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049852213.1	9	MetaCyc: PWY-6167;MetaCyc: PWY-7991;KEGG: 00740+2.5.1.9;KEGG: 00195+7.1.2.2;Reactome: R-HSA-196757;KEGG: 00190+7.1.2.2;KEGG: 00740+3.5.4.26+1.1.1.193;MetaCyc: PWY-6168;MetaCyc: PWY-7980	"Flavin biosynthesis II (archaea)";"Toxoflavin biosynthesis";"Riboflavin metabolism";"Photosynthesis";"Metabolism of folate and pterines";"Oxidative phosphorylation";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"ATP biosynthesis"
XP_049853207.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_049861093.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049853018.1	3	Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269	"Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_049862724.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049829516.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049848007.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049864646.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049859798.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049828459.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049852716.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049859343.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_049827172.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049838138.1	14	MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5078;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5108;Reactome: R-HSA-70895	"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"Glucosinolate biosynthesis";"L-leucine degradation III";"L-isoleucine degradation II";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism"
XP_049841859.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049864766.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049864050.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049833191.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049837853.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049847661.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049864235.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049833503.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049853826.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049839432.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Ub-specific processing proteases"
XP_049843078.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049845619.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049854187.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049861234.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049861424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049837852.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049853670.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049848409.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049834105.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-380972	"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049845616.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049829474.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049858172.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049830328.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833145.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049841328.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_049862754.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA"
XP_049840481.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-1236394;Reactome: R-HSA-1251985;Reactome: R-HSA-1250342;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-1250347;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993	"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Signaling by ERBB4";"Nuclear signaling by ERBB4";"PI3K events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling"
XP_049831884.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049862694.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049852412.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049857833.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049861423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861761.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis"
XP_049828771.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049848703.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049862729.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination"
XP_049861684.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049858314.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049859909.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049846411.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_049856843.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049828160.1	13	MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9	"Folate polyglutamylation";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"L-histidine degradation III";"One carbon pool by folate"
XP_049842621.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049827447.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049848116.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049851896.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049835780.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049832608.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049841856.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049863855.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport"
XP_049862342.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049858083.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria"
XP_049840680.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049856838.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049842335.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049833890.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049859324.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis"
XP_049859707.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049837207.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049849467.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_049837907.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049859192.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049855906.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049843873.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049862736.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049862229.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049847888.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049847576.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049827593.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857090.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049838749.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049829709.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049840001.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049851429.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049859080.1	31	MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-7388;MetaCyc: PWY-4381;Reactome: R-HSA-199220;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5142;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis"
XP_049851240.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_049835498.1	18	KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115	"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049848768.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852988.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408	"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation"
XP_049826896.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-428890	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling"
XP_049852919.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049844154.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049834625.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049827575.1	3	Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2	"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway"
XP_049847965.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049851458.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049855367.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;MetaCyc: PWY-7511	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination"
XP_049851994.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049838140.1	14	MetaCyc: PWY-5101;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5078;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5103	"L-isoleucine biosynthesis II";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-leucine degradation III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III"
XP_049830245.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049838790.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049829863.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049847858.1	6	KEGG: 00983+2.4.2.8;MetaCyc: PWY-6620;MetaCyc: PWY-6599;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6609;MetaCyc: PWY-6610	"Drug metabolism - other enzymes";"Guanine and guanosine salvage";"Guanine and guanosine salvage II";"Purine metabolism";"Adenine and adenosine salvage III";"Adenine salvage"
XP_049832578.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049829700.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049846555.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049857428.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049839261.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049831413.1	21	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187	"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049828650.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
XP_049829738.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049857292.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049861121.1	9	Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049853556.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049858331.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110331	"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine"
XP_049834084.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049862900.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Neutrophil degranulation";"Cargo concentration in the ER"
XP_049859349.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174414	"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere"
XP_049842185.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL"
XP_049852107.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288	"MAP2K and MAPK activation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1"
XP_049853416.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_049854751.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049860150.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049844283.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049861232.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049848789.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049864819.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049859070.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049859369.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_049837009.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049838743.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049859055.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049841426.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049833054.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049828800.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049826885.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049850590.1	6	Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-2151201	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis"
XP_049839392.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049829621.1	13	MetaCyc: PWY-8052;Reactome: R-HSA-202433;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;Reactome: R-HSA-2029485;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"Generation of second messenger molecules";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule"
XP_049844040.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049830814.1	9	MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_049848921.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049861031.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101	"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation"
XP_049864284.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049854496.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_049840582.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049847682.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049840056.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049855980.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049852596.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049858514.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049854244.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555	"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events"
XP_049861252.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049857629.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_049843501.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-5250924;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-73762	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"B-WICH complex positively regulates rRNA expression";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation"
XP_049835246.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049846300.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049844546.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049850593.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049836564.1	18	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_049826893.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213	"T cell receptor signaling pathway";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs"
XP_049859723.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system"
XP_049833814.1	5	KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_049859554.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049839561.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_049828146.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049834005.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_049833087.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049839733.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847620.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049862154.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049834427.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049852191.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049859022.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049832567.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049840630.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049861040.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049856861.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049832522.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049849312.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049845869.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049828257.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049840716.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049844564.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049844713.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049857231.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049862568.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049858288.1	10	MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166	"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA"
XP_049827121.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049861206.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049855617.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Interleukin-1 signaling"
XP_049844782.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049852592.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049857087.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049849200.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049850431.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049851417.1	2	Reactome: R-HSA-73817;Reactome: R-HSA-196780	"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism"
XP_049857367.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049853676.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049828407.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism"
XP_049856064.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049864476.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049829644.1	6	MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_049852548.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049844535.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049858697.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049834097.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049863710.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_049848591.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049846706.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049863408.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049843021.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049848413.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049851940.1	7	MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205	"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose"
XP_049848877.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049862876.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_049836861.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049864641.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049831619.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_049844919.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049857104.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049849247.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049838136.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_049860471.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_049854478.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049856884.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_049861030.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series"
XP_049846075.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835911.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049846737.1	12	MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-7901;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842	"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Glutathione-mediated detoxification II"
XP_049862755.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049848147.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049864239.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848457.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049842159.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852458.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049848082.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864395.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049849670.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049833464.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049864270.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_049858405.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471	"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_049838511.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861	"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly"
XP_049835844.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049862179.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049836843.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049849191.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049856715.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049849815.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_049853035.1	11	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049856990.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_049853624.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049828057.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049847799.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049856089.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_049848738.1	9	Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108	"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049858761.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049838958.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847115.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049851441.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_049844280.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049839800.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_049844262.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049850797.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_049862890.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163359	"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation"
XP_049848670.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049862826.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854917.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049835861.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation"
XP_049851328.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049832523.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049840715.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049836757.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049855642.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049856491.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
XP_049837960.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_049854194.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049844193.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049837813.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049864282.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049836393.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049837753.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049861579.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049859085.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049846982.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049848647.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049830223.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049850251.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049833120.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049849301.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049839722.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049863222.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049842994.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049853492.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049861115.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049840611.1	4	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049833308.1	10	Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5607761	"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049844880.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049862393.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853811.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049832439.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049862735.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049852694.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049862892.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049864372.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049847350.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049844842.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049828710.1	5	MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_049840231.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis"
XP_049848118.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_049835875.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049849370.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049847430.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049829229.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049831388.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049859066.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829380.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049831798.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049862226.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049838913.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049835950.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174184	"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049830144.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142	"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"HCMV Late Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins"
XP_049852839.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_049829479.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049831817.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049854418.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049850228.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049858024.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049836178.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression"
XP_049831833.1	5	Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685	"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_049859526.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_049848821.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_049832222.1	20	MetaCyc: PWY-7227;Reactome: R-HSA-499943;Reactome: R-HSA-380320;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7210;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187	"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049828461.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049856411.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049833408.1	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049846073.1	5	Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_049853730.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049858353.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049859527.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_049856182.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)"
XP_049850063.1	5	Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_049833439.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049847993.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-167590	"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation"
XP_049838716.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049835232.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049834352.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049856799.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049838844.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049846744.1	6	Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-9640463	"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis"
XP_049844801.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
XP_049863093.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049837746.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_049833247.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049847439.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049834596.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049827534.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049852896.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049858679.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049862733.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049833212.1	10	KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_049863381.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049861371.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049833050.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049853509.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049864623.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836981.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5140745	"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_049833425.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049831573.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049850791.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_049851241.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049849954.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049851108.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049846959.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049843090.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049860538.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049828352.1	12	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049840831.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049839257.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049857015.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049847208.1	11	Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1	"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection"
XP_049848598.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049860539.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049838291.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049835994.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049843787.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049842722.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049827040.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049833284.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;MetaCyc: PWY-7919	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)"
XP_049851189.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049864622.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049863267.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_049834598.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049827828.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049843022.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049863709.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_049849484.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049853873.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049856570.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049848009.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049863387.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049846345.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049829783.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane"
XP_049864255.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_049841423.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049847287.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049847780.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834666.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049829515.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049851480.1	3	Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049861885.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-881907;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors"
XP_049852614.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049853579.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins"
XP_049827154.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049830280.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_049862412.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049842149.1	9	Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;MetaCyc: PWY-6142;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1	"Biotin transport and metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes"
XP_049835233.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049851718.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049837218.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_049848385.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858	"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity"
XP_049856213.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049827835.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049837598.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_049856745.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049855952.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049837524.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049827993.1	2	Reactome: R-HSA-203754;MetaCyc: PWY-7511	"NOSIP mediated eNOS trafficking";"Protein ubiquitination"
XP_049843575.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049861090.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_049831318.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049852311.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049831574.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049861537.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049862401.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844861.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049828413.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049829979.1	7	Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134	"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylketonuria";"Folate biosynthesis";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV"
XP_049841961.1	16	Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571	"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)"
XP_049843323.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_049845824.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049856512.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049845901.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049857780.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049829339.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049848786.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222	"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_049854807.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049837101.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049860502.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049838589.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049852162.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049861821.1	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_049831489.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049848774.1	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Proline catabolism";"Alanine, aspartate and glutamate metabolism"
XP_049851833.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_049830403.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049863925.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_049849192.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049858762.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049848790.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049828197.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049861609.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_049856232.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049827747.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049861407.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844355.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049847451.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049845650.1	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_049833770.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049857938.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049847471.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049864700.1	8	KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1	"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism"
XP_049854602.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049830407.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049838421.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049851188.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049847101.1	4	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_049829762.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049832716.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049837455.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_049850649.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049836364.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049853843.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049836781.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049833330.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049837756.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049860503.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049856941.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049836985.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_049860963.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049831389.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049856834.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_049834873.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049840983.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049830200.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633	"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049852671.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049835658.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049844841.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049861405.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844517.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049843083.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049839546.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049842060.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049852830.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049835781.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049831710.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_049844337.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049839269.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049859091.1	6	MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1	"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism"
XP_049830011.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049851182.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_049855794.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761	"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049837719.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049850859.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049861888.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049833181.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049826926.1	8	MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation"
XP_049847893.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049858099.1	10	MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_049855305.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_049830698.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049830794.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049861615.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049850131.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049863102.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049843666.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049834163.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_049830996.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049839412.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049833449.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049833422.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049859196.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049840534.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049832023.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049858417.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049846517.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049836359.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049864154.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049836350.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049829772.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049847233.1	19	MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5392;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_049835189.1	14	MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-6607;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4+1.17.3.2;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;Reactome: R-HSA-74259;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6596;Reactome: R-HSA-8851680	"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation I";"Drug metabolism - other enzymes";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine catabolism";"Caffeine metabolism";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions"
XP_049841737.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049834372.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049854275.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049834665.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049854754.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049838640.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049864645.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049840051.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049858329.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110331	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine"
XP_049850320.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049840312.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049837750.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049848302.1	8	KEGG: 00400+4.2.1.10;MetaCyc: PWY-6416;MetaCyc: PWY-6163;MetaCyc: PWY-6707;KEGG: 00400+4.2.3.4;MetaCyc: PWY-6164;KEGG: 00400+2.7.1.71;KEGG: 00400+2.5.1.19	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Quinate degradation II";"Chorismate biosynthesis from 3-dehydroquinate";"Gallate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_049828645.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
YP_010417157.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049864644.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049841233.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049828728.1	9	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.23;KEGG: 00511+3.2.1.25;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049828254.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049849023.1	6	Reactome: R-HSA-193368;Reactome: R-HSA-389887;Reactome: R-HSA-390247;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;Reactome: R-HSA-2046106	"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Beta-oxidation of pristanoyl-CoA";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"alpha-linolenic acid (ALA) metabolism"
XP_049845202.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049844396.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049857173.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049848788.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_049849404.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049848450.1	13	Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400	"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049864647.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049838486.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_049847323.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049862382.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847305.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049838162.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049830707.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049840003.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049833626.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049863005.1	4	KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049863966.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049857545.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049864041.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049852855.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049850930.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049850091.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049856231.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049857542.1	16	Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-167290	"Neddylation";"RNA Polymerase II Transcription Elongation";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation"
XP_049832984.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_049851432.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049827201.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_049852932.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497	"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049829480.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049835767.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049864188.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852768.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049832167.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850327.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049837648.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049844302.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049851947.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049857159.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049859378.1	26	Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300	"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors"
XP_049833571.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049847615.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049833686.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis"
XP_049858173.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049834223.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_049852624.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_049830673.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049862752.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA"
XP_049837764.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049847853.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049841383.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049841897.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049850476.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049861866.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049856698.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049859077.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049840158.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049853546.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_049835870.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049847385.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049857624.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049839207.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049840711.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049837627.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_049852227.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049852013.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_049854243.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (z) signalling events"
XP_049860622.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049858694.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049863954.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049864501.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828642.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844595.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049839988.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049864274.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049845476.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_049853596.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049841938.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation"
XP_049837815.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049834943.1	9	Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049861110.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_049844278.1	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680	"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity"
XP_049852714.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049845492.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049863695.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_049859382.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568	"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase"
XP_049836406.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049853456.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049856753.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049863634.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049857950.1	8	MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-7573	"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis"
XP_049848250.1	32	Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex"
XP_049849534.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_049830575.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049833405.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049831727.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049863067.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_049829879.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049846591.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981	"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Endogenous sterols";"Xenobiotics"
XP_049841727.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_049833523.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049852254.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049859716.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049856276.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049860602.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049847556.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049856221.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049849974.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049852438.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467	"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_049830022.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_049859402.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_049836221.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049838641.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049843508.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852738.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049864383.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049844961.1	5	Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-6804756	"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation"
XP_049838959.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049829469.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049844109.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049827518.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049857988.1	5	Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_049852515.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049835446.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049843507.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049853149.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049835881.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049858047.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Propanoate metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049854438.1	17	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049838736.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049858384.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049828588.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011	"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance"
XP_049844353.1	5	KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"One carbon pool by folate"
XP_049852659.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850351.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049860172.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination"
XP_049848633.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049842929.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049828519.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049860825.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049855520.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_049839664.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049830613.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_049841230.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_049851922.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049828457.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049836217.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049828201.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049860140.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049863996.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049854337.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049841577.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049845477.1	6	MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17	"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism"
XP_049853831.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_049833193.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049861089.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_049840262.1	12	MetaCyc: PWY-7385;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13	"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism"
XP_049847453.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049863860.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049845398.1	13	KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-4341670;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"MPS IV - Morquio syndrome B";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis";"Keratan sulfate degradation";"Neutrophil degranulation";"Other glycan degradation";"Glycosaminoglycan degradation"
XP_049861377.1	10	MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
XP_049852099.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049849430.1	3	KEGG: 00920+2.7.7.5;MetaCyc: PWY-5279;KEGG: 00230+2.7.7.53	"Sulfur metabolism";"Sulfite oxidation II";"Purine metabolism"
XP_049863893.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049857001.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049845199.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049847571.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049841689.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049853025.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049832042.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049852990.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049859318.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_049858952.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049828082.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_049836348.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049852442.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049863967.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049839061.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_049858635.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049864228.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049864572.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism"
XP_049839702.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049845484.1	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_049852117.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049827014.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049847064.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049833604.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049837157.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049837744.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_049829303.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049853900.1	7	KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049839845.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049844292.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049839416.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049852400.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049844153.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049839710.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049858344.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_049839419.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049853901.1	5	KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_049848020.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049830282.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049854923.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049852563.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049857541.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-75955;Reactome: R-HSA-8951664	"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Transcription Elongation";"Neddylation"
XP_049828098.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049851141.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049847300.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_049845746.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_049844112.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049844227.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049846314.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049856521.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049861353.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049857034.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861404.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844937.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049830882.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836163.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049852465.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049845984.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049833779.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049857899.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049850239.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049835474.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848197.1	14	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism"
XP_049851051.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049852784.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049841995.1	9	Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049858310.1	8	Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-5269;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27	"Synthesis of PG";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism"
XP_049846242.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Fanconi Anemia Pathway";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049828739.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049829434.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_049846656.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128	"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling"
XP_049848199.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_049859588.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_049863513.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049832257.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049852545.1	22	MetaCyc: PWY-6981;KEGG: 00520+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6992;Reactome: R-HSA-6798695;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;MetaCyc: PWY-622;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-7385;MetaCyc: PWY-5054;MetaCyc: PWY-5659;MetaCyc: PWY-5514;Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-6142;MetaCyc: PWY-5384;MetaCyc: PWY-3801;MetaCyc: PWY-621	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"1,5-anhydrofructose degradation";"Neutrophil degranulation";"Glycolysis";"Gluconeogenesis";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Starch biosynthesis";"Pentose phosphate pathway";"Sucrose biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose degradation II (sucrose synthase)";"Sucrose degradation III (sucrose invertase)"
XP_049854135.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049853192.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049836081.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049830501.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049859913.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049862864.1	16	Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828	"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis"
XP_049861725.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049837026.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049827506.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049840826.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847289.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049852623.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049827317.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049836481.1	5	MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation"
XP_049832306.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049848976.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049845620.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049836579.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049842142.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049847288.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049830346.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049851640.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049849766.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049838910.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049834771.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_049844043.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049850361.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049829392.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049863031.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049852087.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049863629.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700	"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_049838349.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049846302.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049850420.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049854507.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411	"G1/S-Specific Transcription";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere"
XP_049850495.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_049850862.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049860959.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049857405.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049834289.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_049837183.1	34	Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-69231	"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1"
XP_049850163.1	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049844960.1	7	Reactome: R-HSA-1855204;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049857961.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049831152.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049834933.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_049835982.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049848820.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_049831181.1	10	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism"
XP_049858416.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471	"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response"
XP_049841394.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049832536.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049862192.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049859432.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049831331.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049849336.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049847779.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation"
XP_049861432.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049848557.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_049848902.1	13	MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7384;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)"
XP_049848525.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049852363.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049860082.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049840044.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049858925.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049835223.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049861344.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049858250.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049833240.1	17	MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes"
XP_049851861.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_049837536.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049836611.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049852783.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049844102.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049850814.1	7	Reactome: R-HSA-201722;Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_049855035.1	6	MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17	"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway"
XP_049850436.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-373080	"Hedgehog 'on' state";"Activation of SMO";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)"
XP_049851828.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049850280.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049829704.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049835447.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049828060.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049832666.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_049830688.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049846416.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049846182.1	14	KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-6453	"Glycerolipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_049863363.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049848306.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049847901.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049857918.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049846567.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049844617.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049858354.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049850075.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049829558.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049832477.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_049830526.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049860597.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049863120.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049836222.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049858406.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049858979.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_049844518.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049853849.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049858693.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_049852218.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_049852984.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408	"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation"
XP_049857123.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049836588.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049858426.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049858469.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049834504.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049841422.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_049852287.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_049841465.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049863235.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_049827788.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049844551.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049852975.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049844360.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049849299.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049832721.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_049859063.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049836605.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049854186.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049834423.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049850589.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049827838.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049834517.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049836062.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049858177.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049830622.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049836680.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049835528.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049844766.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049848303.1	2	KEGG: 00400+2.5.1.54;MetaCyc: PWY-6164	"Phenylalanine, tyrosine and tryptophan biosynthesis";"3-dehydroquinate biosynthesis I"
XP_049842871.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049864187.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049840666.1	17	MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"Pyruvate metabolism"
XP_049844791.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049852594.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049859191.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049830885.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049838647.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049842146.1	9	MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Pyruvate metabolism"
XP_049845674.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049854797.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049856092.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_049828721.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049857177.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome"
XP_049843326.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_049853275.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049831962.1	52	Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-749476;Reactome: R-HSA-9018519;Reactome: R-HSA-167200	"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Dual incision in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Abortive And Retractive Initiation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049833492.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049856724.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049829470.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049840005.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049842597.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049857414.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049833458.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049851932.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049828941.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049844770.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049830284.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_049860559.1	18	KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"(R)-cysteate degradation"
XP_049859356.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049850727.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822	"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_049831449.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_049854600.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049838408.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049863927.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049841211.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049841853.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049851453.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049841963.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049833305.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5607761	"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049842341.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844600.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049829340.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049847400.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049831065.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_049862664.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049851639.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_049844543.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049864068.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049835951.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049832284.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049852776.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049842359.1	7	Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"Cristae formation";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation"
XP_049829221.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049829010.1	15	MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-5723	"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Rubisco shunt"
XP_049834067.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_049838955.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_049826866.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049839120.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828684.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049842059.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049834805.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049862827.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049842225.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049835562.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049827521.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_049848947.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049847277.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049859560.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049848988.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049855935.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049857097.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049831792.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049862130.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049833122.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049845420.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_049831613.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049848237.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049852037.1	29	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803204;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-69541;KEGG: 05170+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-6803207;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"mTOR signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Stabilization of p53";"Human immunodeficiency virus 1 infection";"Autodegradation of the E3 ubiquitin ligase COP1";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049861891.1	14	KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109	"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PE";"Plasmalogen biosynthesis";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis"
XP_049851494.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049842057.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049862491.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049846708.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049846774.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049830308.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_049839428.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049829798.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049862655.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049840528.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049862673.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049852551.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049843010.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049857094.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049846297.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049837981.1	44	Reactome: R-HSA-375165;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654726;Reactome: R-HSA-2559580;Reactome: R-HSA-198753;Reactome: R-HSA-5654732;Reactome: R-HSA-162658;Reactome: R-HSA-5668599;Reactome: R-HSA-9635465;Reactome: R-HSA-456926;Reactome: R-HSA-444257;Reactome: R-HSA-2029482;Reactome: R-HSA-9634638;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-982772;Reactome: R-HSA-5673001;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;Reactome: R-HSA-5674499;Reactome: R-HSA-879415;Reactome: R-HSA-8940973;Reactome: R-HSA-74749;Reactome: R-HSA-6802952;Reactome: R-HSA-5654733;Reactome: R-HSA-2559585;Reactome: R-HSA-8943724;Reactome: R-HSA-5663213;Reactome: R-HSA-202670;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-445144;Reactome: R-HSA-6802946;Reactome: R-HSA-5654727;Reactome: R-HSA-9627069;Reactome: R-HSA-1295596;Reactome: R-HSA-5674135;Reactome: R-HSA-3371453;Reactome: R-HSA-6802948;Reactome: R-HSA-881907;Reactome: R-HSA-6811558;Reactome: R-HSA-2871796	"NCAM signaling for neurite out-growth";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Negative regulation of FGFR1 signaling";"Oxidative Stress Induced Senescence";"ERK/MAPK targets";"Negative regulation of FGFR3 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"RHO GTPases Activate NADPH Oxidases";"Suppression of apoptosis";"Thrombin signalling through proteinase activated receptors (PARs)";"RSK activation";"Regulation of actin dynamics for phagocytic cup formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"Growth hormone receptor signaling";"RAF/MAP kinase cascade";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Negative feedback regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"RUNX2 regulates osteoblast differentiation";"Signal attenuation";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR4 signaling";"Oncogene Induced Senescence";"Regulation of PTEN gene transcription";"RHO GTPases Activate WASPs and WAVEs";"ERKs are inactivated";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signal transduction by L1";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR2 signaling";"Regulation of the apoptosome activity";"Spry regulation of FGF signaling";"MAP2K and MAPK activation";"Regulation of HSF1-mediated heat shock response";"Signaling by high-kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FCERI mediated MAPK activation"
XP_049863787.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049828641.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049831307.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880	"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases"
XP_049858112.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049846296.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049864052.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049847575.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049845719.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049845196.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_049858080.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_049856098.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049847897.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049862387.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847119.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8963888	"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"LDL remodeling";"VLDL clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Platelet sensitization by LDL";"Chylomicron assembly"
XP_049849021.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049830051.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_049857968.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049827443.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049864558.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049848975.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049848835.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049838855.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886	"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"HDMs demethylate histones";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_049845511.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049848340.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049841739.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_049830419.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049862732.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049859060.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049842040.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049842343.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049862528.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049849454.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049853922.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_049845649.1	7	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_049851438.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049837268.1	3	Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049842179.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122	"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049833684.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_049855536.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837035.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049839985.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-68827	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex"
XP_049828198.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049846544.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_049833006.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049857821.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049847044.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049862447.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049858915.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049862582.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049834065.1	1	Reactome: R-HSA-6804115	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049833016.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166	"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_049830979.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049849280.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049859094.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049842334.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049855969.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049842703.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_049864322.1	6	KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613	"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation"
XP_049840865.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049831064.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049845682.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049855109.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049850283.1	7	KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-204174	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049836289.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049850639.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049849603.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049861361.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049831491.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049864765.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049830448.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_049852018.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_049861118.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049851812.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049852190.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049847699.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049833403.1	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049839817.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049853214.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_049838635.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049839216.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049864818.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049829713.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049847386.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049854865.1	10	Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Inhibition of membrane repair";"Ub-specific processing proteases";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049852211.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049835909.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049827214.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_049855874.1	5	KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4	"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism"
XP_049838566.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_049857172.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_049854329.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049863965.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049861038.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049827208.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049837391.1	6	MetaCyc: PWY-6367;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_049850900.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049843512.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049857929.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049830182.1	32	Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167243	"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery"
XP_049846614.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049864172.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049830947.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_049843733.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049828697.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049851488.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049863350.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049857773.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049837181.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049851452.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049836233.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049864365.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049829576.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049855991.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049828713.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049858303.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins"
XP_049839353.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049838527.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049832073.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049853921.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_049859097.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049850433.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049845977.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830617.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049835959.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049840308.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_049845315.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049859082.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049863411.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049841766.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049829577.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049851537.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049860235.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049828161.1	13	KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;Reactome: R-HSA-196757	"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines"
XP_049841560.1	56	Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785	"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome"
XP_049858945.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049832060.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes"
XP_049860808.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation"
XP_049828529.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_049846159.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049848548.1	12	KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049827076.1	15	Reactome: R-HSA-9665245;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-1227986;Reactome: R-HSA-9665250;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-5637810;Reactome: R-HSA-9665247	"Resistance of ERBB2 KD mutants to tesevatinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to osimertinib"
XP_049831875.1	24	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467	"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_049852038.1	29	Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-349425;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69541;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-6804760;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-3371453;Reactome: R-HSA-6804757;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-6803204;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756	"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"mTOR signaling pathway";"Sensing of DNA Double Strand Breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"Human immunodeficiency virus 1 infection";"Stabilization of p53";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Methylation";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"Relaxin signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Degradation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Human cytomegalovirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation"
XP_049844463.1	57	Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex"
XP_049847189.1	4	Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889	"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes"
XP_049837184.1	34	Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-69273;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-5696395	"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of Incision Complex in GG-NER"
XP_049845820.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049832710.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049862877.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049844309.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049840734.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049833255.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049849574.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049864328.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria"
XP_049835190.1	14	MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;MetaCyc: PWY-6351;Reactome: R-HSA-399997;MetaCyc: PWY-8052;Reactome: R-HSA-434316;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Ca2+ pathway";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"D-myo-inositol-5-phosphate metabolism"
XP_049829779.1	20	KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854	"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_049859754.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049859622.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534	"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4"
XP_049864618.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049853704.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049851581.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-203927	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis"
XP_049853269.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049838690.1	52	Reactome: R-HSA-76066;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-112382	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex"
XP_049843596.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049857865.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049853545.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049854789.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049840787.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_049858212.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
XP_049838260.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway"
XP_049864556.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049840060.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049861747.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049827830.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049857313.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049842412.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049854475.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049841382.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049829955.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2206292	"Neutrophil degranulation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"MPS VII - Sly syndrome"
XP_049852106.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049829556.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049837245.1	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049862425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836979.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049849146.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049859424.1	19	Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-3214858;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049863784.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049844519.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049841219.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_049833005.1	29	Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-167158	"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex"
XP_049840741.1	14	Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665	"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells"
XP_049833878.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049858678.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049830831.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1	"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis"
XP_049851152.1	20	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HSF1-dependent transactivation";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signalling";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability"
XP_049847397.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049857269.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049839554.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096	"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation";"HS-GAG degradation"
XP_049840024.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049849053.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049827217.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism"
XP_049860169.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049834871.1	18	MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
XP_049847304.1	2	KEGG: 00450+1.8.1.9;Reactome: R-HSA-499943	"Selenocompound metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049851510.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049850842.1	17	Reactome: R-HSA-167243;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-75955;KEGG: 04660+3.1.3.16	"Tat-mediated HIV elongation arrest and recovery";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"T cell receptor signaling pathway"
XP_049858980.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans"
XP_049835550.1	4	Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049860493.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049849305.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_049850087.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049847347.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049834899.1	33	Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-69231;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-73776	"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin D associated events in G1";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape"
XP_049858113.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049851574.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049857402.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049844133.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049829486.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049833941.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049848938.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049832534.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049827541.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049835815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049860227.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049863014.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158	"Circadian Clock";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_049851908.1	7	KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-6840	"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis"
XP_049861215.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049840898.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049857229.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-5619107	"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_049835548.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049838620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049843845.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049831277.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049852943.1	6	Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3	"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_049848778.1	18	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_049851135.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_049829477.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049857933.1	8	Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-165054	"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA"
XP_049846631.1	57	Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858	"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity"
XP_049860594.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049834309.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049864038.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049857377.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049859222.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049831485.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049858586.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049828261.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049862699.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049863705.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049851585.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-212436	"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway"
XP_049858455.1	3	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049840006.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049838904.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049852181.1	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538	"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI"
XP_049826891.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2	"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"T cell receptor signaling pathway"
XP_049854271.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828679.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049830214.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049840667.1	17	Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1	"Carnitine metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Propanoate metabolism";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_049853729.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049851616.1	5	Reactome: R-HSA-9033500;MetaCyc: PWY-7782;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import"
XP_049850980.1	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
XP_049828370.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049837466.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049851967.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801	"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD"
XP_049831583.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049830550.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049864461.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049854934.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049853862.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049830497.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049840535.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049847885.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049836973.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049848014.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049836547.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049841377.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847598.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049857400.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049845699.1	16	MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5749;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.4;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403	"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)"
XP_049864238.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049847200.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049836483.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_049849059.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049857651.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049844710.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049858675.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049848618.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049863092.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049852639.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049843732.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049833979.1	17	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits"
XP_049838995.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049854245.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-170660	"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway"
XP_049847987.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049864583.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049854473.1	4	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
XP_049832231.1	20	MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7176;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7224;Reactome: R-HSA-380320;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Recruitment of NuMA to mitotic centrosomes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049847877.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049863808.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049837107.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049863488.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049836966.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049851995.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049837660.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049838747.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049839152.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism"
XP_049840707.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049838219.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049843447.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049846237.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049841281.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049864156.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049841184.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049849457.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049864046.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049856469.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843729.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049842028.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-176034;Reactome: R-HSA-2173796;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Interactions of Tat with host cellular proteins";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex"
XP_049864767.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049836638.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049827319.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049863995.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049851601.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049835255.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049851917.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049848058.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049827020.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049845342.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049833242.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017	"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_049831239.1	10	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292	"Neutrophil degranulation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"MPS VII - Sly syndrome"
XP_049858343.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-168333	"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049863382.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER"
XP_049847822.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049827079.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049834400.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616	"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication"
XP_049838776.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049844598.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_049848989.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs"
XP_049857595.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)"
XP_049857145.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049835387.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049858930.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049850286.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Neutrophil degranulation";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049842324.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049854246.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049860505.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049851566.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049854112.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049844909.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_049840601.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049839094.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049844494.1	10	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation";"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1"
XP_049834369.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049861689.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049830286.1	5	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_049837718.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836145.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_049839356.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049859549.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049864251.1	7	KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system"
XP_049848196.1	14	KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416	"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_049830494.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049851938.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_049846315.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049841186.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049836148.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_049861494.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_049861419.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853466.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049844882.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049838665.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049830089.1	6	KEGG: 00670+2.1.2.5;MetaCyc: PWY-5497;Reactome: R-HSA-70921;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;KEGG: 00340+2.1.2.5	"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Histidine catabolism";"One carbon pool by folate";"L-histidine degradation III";"Histidine metabolism"
XP_049861536.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049851708.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049841327.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049836617.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-380320	"MHC class II antigen presentation";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes"
XP_049847252.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_049831486.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049830023.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_049846582.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049855760.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049841888.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL"
XP_049864047.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049841851.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049841221.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_049855488.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049862078.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049853148.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049839541.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049827740.1	6	MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004	"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Entner-Doudoroff pathway I"
XP_049863314.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632	"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis"
XP_049841018.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049860147.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049829069.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049837033.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049864480.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_049862855.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049848025.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049831805.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049841729.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_049833144.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049830183.1	32	Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167287	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery"
XP_049841130.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607	"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends"
XP_049828083.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176412	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C"
XP_049849420.1	19	Reactome: R-HSA-5389840;Reactome: R-HSA-975956;Reactome: R-HSA-5419276;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Mitochondrial translation elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Mitochondrial translation termination";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049831290.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049827549.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-532668;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815	"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D"
XP_049857849.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049850820.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049859536.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049856394.1	13	Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674135	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"Relaxin signaling pathway";"MAP2K and MAPK activation"
XP_049854269.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049864548.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049851418.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_049844594.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049838661.1	19	KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-70263;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37	"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Methane metabolism";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)"
XP_049852206.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049849912.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049843351.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
XP_049860155.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049850526.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049862618.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-1042	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis IV (plant cytosol)"
XP_049835843.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049842336.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844736.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_049857936.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049853800.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049840564.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049848294.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049848363.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049842279.1	5	Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6289;MetaCyc: PWY-6012	"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Petrobactin biosynthesis";"Acyl carrier protein metabolism"
XP_049832067.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049837388.1	6	MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
XP_049853938.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049863347.1	3	Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import"
XP_049850435.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_049832472.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049857246.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_049830400.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049829689.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049850812.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_049837372.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049856500.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049861587.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049836710.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_049833735.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049828377.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049862076.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049830343.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049827882.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049861746.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_049844712.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049859878.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049841513.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049849227.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049844042.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049846333.1	5	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism"
XP_049845698.1	16	MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5749;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00020+6.2.1.4;KEGG: 00660+6.2.1.5	"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Propanoate metabolism";"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism"
XP_049848940.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_049858241.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049833962.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_049830433.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_049862550.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049849632.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049829381.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049832818.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049827584.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049849453.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049836685.1	6	Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597	"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events"
XP_049846917.1	12	Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9	"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism"
XP_049845859.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049853591.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049840175.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049837987.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049850229.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049845480.1	6	KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049842211.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049851286.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_049841235.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049830839.1	17	KEGG: 04660+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167243	"T cell receptor signaling pathway";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated HIV elongation arrest and recovery"
XP_049854333.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049827181.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049838180.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049849523.1	9	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_049858556.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049863321.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-5142;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-6113;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-8012	"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Mupirocin biosynthesis"
XP_049850515.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049846720.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049847599.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049859069.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049846723.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049850739.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049859985.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107	"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_049837411.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049850594.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049864290.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049863432.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049860833.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049837139.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049853829.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049830091.1	8	KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-5;MetaCyc: PWY-4983;MetaCyc: PWY-4984;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-5154	"Arginine biosynthesis";"Urea cycle";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049839776.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049845552.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_049833610.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049839993.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049845401.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049862488.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049863409.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049848937.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049854404.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049829624.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049854748.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-72163	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway"
XP_049852255.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049864095.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049839151.1	14	KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587	"Glycerolipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)"
XP_049852007.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine"
XP_049848944.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848763.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049857537.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049857127.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049852134.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049852374.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049862685.1	2	KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_049856867.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_049858852.1	4	MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26	"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049862895.1	4	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_049859885.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049833357.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049853435.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049853434.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_049850428.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049842312.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_049849816.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"mTORC1-mediated signalling";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_049848903.1	13	KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7254;Reactome: R-HSA-71403	"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)"
XP_049860381.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049859362.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049827440.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049830475.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049863154.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049839665.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049850129.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049860679.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736	"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors"
XP_049850384.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049857916.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049861036.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916	"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation"
XP_049862661.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049858059.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049827055.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049856502.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049840778.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049838847.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049841997.1	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049851960.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-5368286;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-5419276;Reactome: R-HSA-975956;Reactome: R-HSA-5389840	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Mitochondrial translation initiation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Mitochondrial translation elongation"
XP_049861191.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049849941.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049846318.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_049845281.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049846969.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049862435.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852578.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_049830871.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083633	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049833281.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049858328.1	7	Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306	"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends"
XP_049833569.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049830769.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049831174.1	4	MetaCyc: PWY-5030;MetaCyc: PWY-5028;Reactome: R-HSA-70921;KEGG: 00340+4.2.1.49	"L-histidine degradation III";"L-histidine degradation II";"Histidine catabolism";"Histidine metabolism"
XP_049826925.1	8	MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation"
XP_049849579.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5578749	"snRNP Assembly";"HCMV Late Events";"HCMV Early Events";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs"
XP_049863604.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049829770.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049838735.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049848772.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049858383.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049858170.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049854059.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_049850489.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars"
XP_049858320.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049836394.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049828917.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049852888.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049859345.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049847272.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049850641.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_049827498.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049857426.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049835194.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049857911.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_049853195.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049847239.1	19	MetaCyc: PWY-5538;Reactome: R-HSA-6798695;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-7384;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403	"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)"
XP_049831679.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049827026.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049833879.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049837664.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049828076.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049832232.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049856866.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049860807.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049852253.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049857610.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049831553.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049862739.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049839423.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049842543.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049861037.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049843091.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049829425.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049854201.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049847303.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_049834204.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049856100.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049833377.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049864687.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049841538.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049843066.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049831445.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_049830631.1	31	MetaCyc: PWY-5142;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-4381;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-6113	"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis"
XP_049861251.1	7	Reactome: R-HSA-6799198;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;MetaCyc: PWY-5083;MetaCyc: PWY-4302;Reactome: R-HSA-611105	"Complex I biogenesis";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Fe(II) oxidation";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport"
XP_049855738.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Macroautophagy";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049851976.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049841561.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601	"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_049847250.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049852241.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049830102.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049858081.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_049838547.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049838631.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049834171.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_049864186.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049837652.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049833149.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049848995.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049857411.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049848350.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_049830132.1	2	Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049850003.1	8	Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-6791461	"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P"
XP_049847752.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049843593.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049851308.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_049857775.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049851524.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049858676.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049863352.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_049848509.1	7	KEGG: 00020+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12	"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism"
XP_049831804.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838742.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049860326.1	12	Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate";"One carbon pool by folate";"Biotin transport and metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049839999.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049854866.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049860348.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049848203.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843	"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation"
XP_049858082.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria"
XP_049862225.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853681.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049850347.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049853507.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049841960.1	16	Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-9018519;Reactome: R-HSA-5693548	"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Estrogen-dependent gene expression";"Sensing of DNA Double Strand Breaks"
XP_049851444.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049829980.1	7	MetaCyc: PWY-6134;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158	"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V"
XP_049847810.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6123;MetaCyc: PWY-6124	"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II"
XP_049841415.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-7039	"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule"
XP_049838912.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049831779.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049853245.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167243	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery"
XP_049859364.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049834254.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049833767.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049846585.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_049828436.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049849465.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049845280.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049833993.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399	"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy"
XP_049850657.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049859512.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049849140.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049827640.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049846036.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049838137.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049829837.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_049863058.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049841175.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049840038.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049861256.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049847506.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049842869.1	7	Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_049852118.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049849927.1	10	MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-4719360	"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_049833294.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state"
XP_049864389.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049864469.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049844149.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_049831418.1	7	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_049859413.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049833325.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049864326.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049860518.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_049838744.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049851546.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049857276.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049828940.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049829073.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049837450.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049831440.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049846895.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870	"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_049863039.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049829220.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049846644.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049847577.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049846061.1	9	MetaCyc: PWY-6682;MetaCyc: PWY-7510;MetaCyc: PWY-7769;MetaCyc: PWY-5757;MetaCyc: PWY-8067;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6839;MetaCyc: PWY-6322;KEGG: 00440+4.1.1.82	"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosalacine biosynthesis";"Fosfomycin biosynthesis";"Methylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"2-aminoethylphosphonate biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosphonate and phosphinate metabolism"
XP_049827221.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_049857574.1	5	KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_049853014.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049847424.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049836137.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049845189.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049829467.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049837137.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049852444.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins"
XP_049837622.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049829520.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049827015.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049856833.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049844158.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_049856616.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049859253.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_049855638.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049831155.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049844696.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation"
XP_049857232.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049854008.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049831156.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049827323.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049849955.1	14	KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7279	"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_049856515.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049852736.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176412	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C"
XP_049844098.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049859428.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049851799.1	5	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-6798695	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation"
XP_049861058.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049862902.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049853633.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049830916.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_049835284.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049849885.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_049862899.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049849456.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049837834.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049847454.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049864649.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049859454.1	30	Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-2644607;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-2644606;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-68949	"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of NF-kappaB in B cells";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"FCERI mediated NF-kB activation";"Neddylation";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin"
XP_049834458.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049841413.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476	"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events"
XP_049845647.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049860620.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049856217.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049849705.1	9	MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-8004	"Glycerol degradation to butanol";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Entner-Doudoroff pathway I"
XP_049831004.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049862766.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_049848974.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049847843.1	29	Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167162	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape"
XP_049841732.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049850877.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049857290.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_049844818.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049841673.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling"
XP_049840052.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049861057.1	7	MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-2029485	"Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis"
XP_049827170.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation"
XP_049849880.1	3	Reactome: R-HSA-1660499;Reactome: R-HSA-114604;Reactome: R-HSA-392451	"Synthesis of PIPs at the plasma membrane";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma"
XP_049853279.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049858680.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946	"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin"
XP_049857226.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049830151.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049827039.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049853924.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049857096.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049857378.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049851783.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049834509.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049828368.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049854077.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049853547.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_049848943.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation"
XP_049853933.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049827256.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049862402.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049854614.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049847458.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation"
XP_049839544.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049858428.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_049829227.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049860260.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_049848603.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_049855404.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049850614.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_049862701.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049847237.1	19	KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-163765;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049859199.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049853786.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049828205.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049857429.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049831776.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049848111.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049830980.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049864060.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049853578.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049840155.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049853111.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049847611.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_049832025.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049834695.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049857219.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049863385.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_049838780.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049839734.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049846707.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049844257.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049842622.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049829872.1	11	MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis"
XP_049835373.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_049853685.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049854346.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049863072.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049854393.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684	"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state"
XP_049839266.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_049863230.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049838225.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049838813.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049856514.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049863241.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049850267.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_049853209.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049842344.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049851467.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_049845278.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport"
XP_049852851.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_049835944.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049836443.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049828437.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049837025.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049836152.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase"
XP_049845705.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049861210.1	33	Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-9609690	"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"HCMV Early Events"
XP_049856906.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049845573.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049864143.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049839715.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049843728.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049861899.1	14	MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism"
XP_049845119.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_049860498.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049850171.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049852670.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844796.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_049851142.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049860465.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049847829.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_049851411.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049845646.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049828572.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049854607.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049844222.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049861497.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049853846.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049861185.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844538.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_049835500.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049852568.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049829679.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049846231.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_049860171.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange"
XP_049829740.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049839181.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049829405.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049855575.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049858352.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049837805.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049858380.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049862558.1	6	MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_049864286.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049857952.1	8	MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-7573;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47	"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism"
XP_049859499.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049838269.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049857222.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049861406.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049850424.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049847790.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3371453	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response"
XP_049853944.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_049827836.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049834818.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049830184.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049856054.1	18	KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I"
XP_049864279.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049830341.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049836083.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049864474.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049852358.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049831471.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049827891.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3881;MetaCyc: PWY-5659	"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"GDP-mannose biosynthesis"
XP_049828675.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049836595.1	7	KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854	"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_049838422.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Degradation of the extracellular matrix";"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049827213.1	6	MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560	"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism"
XP_049849598.1	34	Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-69656;Reactome: R-HSA-427413	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression"
XP_049863435.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049847129.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Platelet degranulation";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants"
XP_049839153.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51	"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism"
XP_049856148.1	6	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle"
XP_049841516.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_049836232.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049834727.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049831614.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_049850608.1	1	KEGG: 00640+4.2.1.79	"Propanoate metabolism"
XP_049835811.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828834.1	7	Reactome: R-HSA-77288;KEGG: 00071+1.3.8.7;MetaCyc: PWY-7094;Reactome: R-HSA-77348;Reactome: R-HSA-77346;KEGG: 00280+1.3.8.7;Reactome: R-HSA-1989781	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid degradation";"Fatty acid salvage";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression"
XP_049850788.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049838622.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049830825.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-7141	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis"
XP_049828152.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049843239.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049838259.1	10	MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13	"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism"
XP_049842395.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049833285.1	5	MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106	"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis"
XP_049832715.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049862741.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_049843790.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049831791.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049849325.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049836952.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049857860.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049849282.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049849873.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049853573.1	4	Reactome: R-HSA-70921;KEGG: 00340+3.5.2.7;MetaCyc: PWY-5028;MetaCyc: PWY-5030	"Histidine catabolism";"Histidine metabolism";"L-histidine degradation II";"L-histidine degradation III"
XP_049839778.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049859749.1	6	Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_049844308.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861190.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049841999.1	27	Reactome: R-HSA-8939902;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-399956;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5250924;Reactome: R-HSA-5467348;Reactome: R-HSA-198323;Reactome: R-HSA-5610785;Reactome: R-HSA-4641262;Reactome: R-HSA-5610783;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;KEGG: 04714+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-5674400	"Regulation of RUNX2 expression and activity";"mTOR signaling pathway";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"CRMPs in Sema3A signaling";"Human immunodeficiency virus 1 infection";"Ubiquitin-dependent degradation of Cyclin D";"B-WICH complex positively regulates rRNA expression";"Truncations of AMER1 destabilize the destruction complex";"AKT phosphorylates targets in the cytosol";"GLI3 is processed to GLI3R by the proteasome";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of GLI2 by the proteasome";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Thermogenesis";"Beta-catenin phosphorylation cascade";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049835889.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049832571.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049862368.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_049839849.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049834348.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049846309.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049864324.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049855815.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049857288.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049838424.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049860460.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049853782.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_049835497.1	179	Reactome: R-HSA-180585;Reactome: R-HSA-937042;Reactome: R-HSA-8951664;Reactome: R-HSA-5675482;Reactome: R-HSA-6781823;Reactome: R-HSA-9615710;Reactome: R-HSA-5693607;Reactome: R-HSA-195253;Reactome: R-HSA-6791226;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-5696397;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-192823;Reactome: R-HSA-9645460;Reactome: R-HSA-2173795;Reactome: R-HSA-68949;Reactome: R-HSA-917729;Reactome: R-HSA-8866654;Reactome: R-HSA-9020702;Reactome: R-HSA-5696395;Reactome: R-HSA-1799339;Reactome: R-HSA-5658442;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-9604323;Reactome: R-HSA-6804760;Reactome: R-HSA-8854050;Reactome: R-HSA-3785653;Reactome: R-HSA-9013973;Reactome: R-HSA-917937;Reactome: R-HSA-901032;Reactome: R-HSA-182971;Reactome: R-HSA-1236382;Reactome: R-HSA-9636383;Reactome: R-HSA-3134975;Reactome: R-HSA-445989;Reactome: R-HSA-4641258;Reactome: R-HSA-8875360;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-5654726;Reactome: R-HSA-382556;Reactome: R-HSA-168928;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-450302;Reactome: R-HSA-936440;Reactome: R-HSA-168927;Reactome: R-HSA-174113;Reactome: R-HSA-2559582;Reactome: R-HSA-209560;Reactome: R-HSA-450321;Reactome: R-HSA-9013507;Reactome: R-HSA-936964;Reactome: R-HSA-5684264;Reactome: R-HSA-8856828;Reactome: R-HSA-110314;Reactome: R-HSA-174490;Reactome: R-HSA-5654733;Reactome: R-HSA-9033241;Reactome: R-HSA-8849469;Reactome: R-HSA-5656169;Reactome: R-HSA-4641257;Reactome: R-HSA-69231;Reactome: R-HSA-2173791;Reactome: R-HSA-5689896;Reactome: R-HSA-1169091;Reactome: R-HSA-912631;Reactome: R-HSA-2691232;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-205043;Reactome: R-HSA-5689880;Reactome: R-HSA-5655862;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-8856825;Reactome: R-HSA-2559580;Reactome: R-HSA-5678895;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5358346;Reactome: R-HSA-975144;Reactome: R-HSA-400253;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-69541;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-201681;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-2672351;Reactome: R-HSA-9646399;Reactome: R-HSA-6782210;Reactome: R-HSA-9613829;Reactome: R-HSA-110312;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-8948747;Reactome: R-HSA-937039;Reactome: R-HSA-174154;Reactome: R-HSA-9014325;Reactome: R-HSA-72706;Reactome: R-HSA-8863795;Reactome: R-HSA-5676590;Reactome: R-HSA-1253288;Reactome: R-HSA-9633012;Reactome: R-HSA-5696394;Reactome: R-HSA-2173796;Reactome: R-HSA-6807004;Reactome: R-HSA-5357956;Reactome: R-HSA-72764;Reactome: R-HSA-5607761;Reactome: R-HSA-174048;Reactome: R-HSA-5685942;Reactome: R-HSA-2122948;Reactome: R-HSA-1358803;Reactome: R-HSA-5668541;Reactome: R-HSA-975110;Reactome: R-HSA-110320;Reactome: R-HSA-1295596;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-5693565;Reactome: R-HSA-6781827;Reactome: R-HSA-5362768;Reactome: R-HSA-8876493;Reactome: R-HSA-8852276;Reactome: R-HSA-5654732;Reactome: R-HSA-6804757;Reactome: R-HSA-5689877;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-179409;Reactome: R-HSA-8866652;Reactome: R-HSA-2565942;Reactome: R-HSA-5357905;Reactome: R-HSA-2173788;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-975163;Reactome: R-HSA-5205685;Reactome: R-HSA-162588;Reactome: R-HSA-2559585;Reactome: R-HSA-2894862;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-4641263;Reactome: R-HSA-168638;Reactome: R-HSA-72689;Reactome: R-HSA-175474;Reactome: R-HSA-9637628;Reactome: R-HSA-69481;Reactome: R-HSA-2122947;Reactome: R-HSA-1169408;Reactome: R-HSA-983168;Reactome: R-HSA-5654727;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-937041;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2979096;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176	"Vif-mediated degradation of APOBEC3G";"IRAK2 mediated activation of TAK1 complex";"Neddylation";"Regulation of necroptotic cell death";"Formation of TC-NER Pre-Incision Complex";"Late endosomal microautophagy";"Processing of DNA double-strand break ends";"Degradation of beta-catenin by the destruction complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Dual incision in TC-NER";"Glycogen synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Viral mRNA Translation";"Alpha-protein kinase 1 signaling pathway";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Orc1 removal from chromatin";"Endosomal Sorting Complex Required For Transport (ESCRT)";"E3 ubiquitin ligases ubiquitinate target proteins";"Interleukin-1 signaling";"Formation of Incision Complex in GG-NER";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of RAS by GAPs";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"Negative regulation of NOTCH4 signaling";"Regulation of TP53 Activity through Methylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Myoclonic epilepsy of Lafora";"TICAM1-dependent activation of IRF3/IRF7";"Iron uptake and transport";"ER Quality Control Compartment (ERQC)";"EGFR downregulation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Prevention of phagosomal-lysosomal fusion";"Regulation of innate immune responses to cytosolic DNA";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Degradation of DVL";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Negative regulation of FGFR1 signaling";"ABC-family proteins mediated transport";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"activated TAK1 mediates p38 MAPK activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"SCF-beta-TrCP mediated degradation of Emi1";"Senescence-Associated Secretory Phenotype (SASP)";"NF-kB is activated and signals survival";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Clathrin-mediated endocytosis";"Recognition of DNA damage by PCNA-containing replication complex";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR4 signaling";"Peroxisomal protein import";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Termination of translesion DNA synthesis";"Degradation of AXIN";"Cyclin D associated events in G1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Ovarian tumor domain proteases";"Activation of NF-kappaB in B cells";"Regulation of signaling by CBL";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"NRIF signals cell death from the nucleus";"Ub-specific processing proteases";"Translesion synthesis by POLK";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Cargo recognition for clathrin-mediated endocytosis";"Oxidative Stress Induced Senescence";"Defective CFTR causes cystic fibrosis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Hedgehog ligand biogenesis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Circadian Clock";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Stabilization of p53";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TCF dependent signaling in response to WNT";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"ER-Phagosome pathway";"Stimuli-sensing channels";"Aggrephagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Chaperone Mediated Autophagy";"Translesion synthesis by REV1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN localization";"IRAK1 recruits IKK complex";"APC/C:Cdc20 mediated degradation of Securin";"TICAM1,TRAF6-dependent induction of TAK1 complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Downregulation of ERBB2 signaling";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"DNA Damage Recognition in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of MET activity";"TNFR1-induced NFkappaB signaling pathway";"Eukaryotic Translation Termination";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"HDR through Homologous Recombination (HRR)";"Activated NOTCH1 Transmits Signal to the Nucleus";"Downregulation of ERBB2:ERBB3 signaling";"TNFR2 non-canonical NF-kB pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Translesion Synthesis by POLH";"Spry regulation of FGF signaling";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"InlA-mediated entry of Listeria monocytogenes into host cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR3 signaling";"Regulation of TP53 Degradation";"Josephin domain DUBs";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC-Cdc20 mediated degradation of Nek2A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TNFR1 signaling";"Downregulation of TGF-beta receptor signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"Budding and maturation of HIV virion";"Oncogene Induced Senescence";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of FZD by ubiquitination";"NOD1/2 Signaling Pathway";"Formation of a pool of free 40S subunits";"Assembly Of The HIV Virion";"Modulation by Mtb of host immune system";"G2/M Checkpoints";"NOTCH1 Intracellular Domain Regulates Transcription";"ISG15 antiviral mechanism";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR2 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"IKK complex recruitment mediated by RIP1";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049826892.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482	"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049844705.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049828153.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049850395.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049849272.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049834758.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049861120.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-1989781	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"PPARA activates gene expression"
XP_049829283.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049835384.1	18	Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-6783984;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-5362517;MetaCyc: PWY-5084;Reactome: R-HSA-70268;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-204174;KEGG: 00640+1.8.1.4	"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Pyruvate metabolism";"Lysine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Propanoate metabolism"
XP_049858210.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation"
XP_049861142.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049846898.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049852402.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049850704.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049847898.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049830208.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_049840309.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049858332.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine"
XP_049850719.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049863846.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049836760.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049842065.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049837468.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736	"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors"
XP_049851805.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049835826.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049829485.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049841855.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049852867.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049854273.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833328.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049862301.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049861844.1	14	MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism"
XP_049855399.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049835191.1	14	Reactome: R-HSA-399997;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-500657;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;MetaCyc: PWY-6351	"Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Presynaptic function of Kainate receptors";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Ca2+ pathway";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049857227.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379	"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events"
XP_049854690.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049845814.1	4	KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_049842326.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049834505.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049858760.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049835890.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049839996.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049847863.1	15	KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1362409;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Glycerolipid metabolism";"Ether lipid metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Triglyceride biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_049844002.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_049836648.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049831834.1	5	Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685	"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_049851128.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_049852622.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049849315.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_049838626.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049834421.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049849594.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_049855003.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049849533.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_049846103.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049831106.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049857158.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049840834.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049854960.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049850720.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA"
XP_049852585.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate"
XP_049830299.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_049842697.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049863273.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049835150.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049860964.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049850501.1	10	Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049830578.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049847422.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049864103.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049841857.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049828649.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-6799198	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis"
XP_049851171.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049846306.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049850973.1	10	Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111457	"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria"
XP_049864161.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049851075.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049852357.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049850642.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_049853494.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049856511.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049860449.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_049856836.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049828432.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049831153.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049857990.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_049839557.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049844565.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049833846.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049862542.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049862822.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049833868.1	7	Reactome: R-HSA-4549356;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265;MetaCyc: PWY-6471	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_049863335.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049849304.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049858326.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_049864430.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049849868.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049856390.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049837878.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049850956.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049860196.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049840641.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_049845753.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049849963.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049837682.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593	"Ca2+ pathway";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity"
XP_049859559.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049833712.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049862033.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049834325.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049859189.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049836007.1	22	MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-7724;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7619	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis"
XP_049852338.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049835136.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_049857134.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049844688.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049857059.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049837686.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049837119.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049851235.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_049844190.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049840061.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_049852971.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_049853848.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049835945.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_049829912.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049853533.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049830776.1	9	MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_049837845.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049850678.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969	"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina"
XP_049843513.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049857283.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049844733.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-392851	"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor"
XP_049826924.1	8	KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086	"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_049855896.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049828648.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049840039.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049851334.1	9	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"Telomere C-strand synthesis initiation";"DNA replication initiation";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
XP_049852505.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049851020.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049840654.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049848977.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049857371.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049829273.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049853865.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049846015.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049858619.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049829153.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049849631.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK"
XP_049851559.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049830164.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049844348.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_049848148.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049863982.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049833470.1	6	KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_049861777.1	14	Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049864512.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049849297.1	2	KEGG: 00400+1.1.1.25;MetaCyc: PWY-6163	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Chorismate biosynthesis from 3-dehydroquinate"
XP_049861840.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049849691.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049839994.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049847943.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049857016.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049833192.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_049830146.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049864104.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049862122.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049846545.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049858165.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049842150.1	9	MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_049828162.1	13	MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9	"Folate polyglutamylation";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate"
XP_049838132.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049860105.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049855400.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049850700.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-983168;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion"
XP_049848013.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049831409.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_049833457.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049847800.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049851821.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049831390.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049859949.1	29	Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-167162	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape"
XP_049830841.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049850711.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_049843965.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049859936.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions"
XP_049846102.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling"
XP_049835234.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049858470.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049850014.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049847570.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049851980.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049837854.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049864120.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049850741.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049830496.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049837747.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049864278.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049844720.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049850987.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049839475.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049852856.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049833230.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049858756.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation"
XP_049856035.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049830651.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors"
XP_049861379.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049853673.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049862413.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861060.1	7	MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148	"Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG"
XP_049828683.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049861239.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-381676	"PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049831862.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs"
XP_049861557.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049838849.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049850758.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049844198.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049840275.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519	"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression"
XP_049864504.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049850650.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049844706.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049835990.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049828945.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049829306.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049833685.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis"
XP_049829331.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049830300.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5855	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_049851551.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049841395.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049849032.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049849471.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049840646.1	14	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-141444;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Macroautophagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_049855804.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049859092.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838750.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049835465.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049832750.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049840048.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049863985.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049846262.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049848223.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049853600.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049854929.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_049842640.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402	"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex"
XP_049861515.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049830367.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049837321.1	4	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis"
XP_049830648.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors"
XP_049862423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049838032.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049860346.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049853814.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049838802.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049840625.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049856452.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049838782.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049831762.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049848758.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049830406.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049845790.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049830358.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049840573.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049844602.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049861521.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049863756.1	52	Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167243	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery"
XP_049845566.1	7	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol"
XP_049836046.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049863401.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049845911.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049830103.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049829409.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049863009.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-210744;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695	"Attenuation phase";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049860385.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857167.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049834552.1	4	MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_049863243.1	9	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway"
XP_049856725.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049852977.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049827100.1	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
XP_049850667.1	4	MetaCyc: PWY-7511;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Protein ubiquitination";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049864719.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049857368.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049831393.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282	"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_049845005.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_049856594.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049849224.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049861594.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049859081.1	31	MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-4381;MetaCyc: PWY-8049;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-6113;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7858	"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II"
XP_049838565.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049851450.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049856239.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049857960.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049836677.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation"
XP_049849076.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049849025.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049857532.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_049860836.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049840040.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049864706.1	8	Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_049837117.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049858121.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049838717.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049843232.1	14	KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661	"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Folate polyglutamylation";"Photorespiration ";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"Folate transformations I";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I"
XP_049826993.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_049831784.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049830199.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions"
XP_049828729.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049845440.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049863971.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049845754.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049858085.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria"
XP_049848694.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049834759.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049838509.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049845628.1	5	Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049861916.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049864173.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049850326.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049844954.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049845673.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049832413.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_049831617.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049833409.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049854420.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049850977.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049848615.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049827042.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049827881.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049835357.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049829327.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049844108.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049844877.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049848162.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049833840.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049854935.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049840111.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049852722.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049840073.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049859688.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049850134.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049859013.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049848093.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049845795.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049861194.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-977225	"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Amyloid fiber formation"
XP_049833029.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049864196.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049858707.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049836444.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049834062.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049837855.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049837482.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049847048.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381	"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_049831615.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_049857168.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049838654.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049831689.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049832837.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049854480.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049850757.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049857315.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049834100.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049851728.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049850581.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049857820.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_049858964.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049836155.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049848556.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049863964.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049844610.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-983695	"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"DAG and IP3 signaling";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_049860771.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-877300	"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Interferon gamma signaling"
XP_049849369.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049846277.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049845140.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049835187.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049833128.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049849672.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_049858528.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049856453.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049834547.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5545483	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1"
XP_049834561.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_049864527.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins"
XP_049832407.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049860448.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_049855631.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049863603.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049849871.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049849154.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_049845993.1	5	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049858932.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049840614.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_049846409.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_049829418.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049852648.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049837187.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049855237.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049860298.1	16	Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-8004	"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Rubisco shunt";"Entner-Doudoroff pathway I"
XP_049859367.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049834415.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049838398.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049838942.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway"
XP_049862457.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049839393.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049840709.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049849839.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049841581.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049858355.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049849449.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049827128.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049861495.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049841679.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_049830415.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_049840314.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049847558.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049835832.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049842416.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049837353.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049837621.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
YP_010417154.1	7	MetaCyc: PWY-6692;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-4302	"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)"
XP_049858001.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049851827.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049832078.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049837513.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"HCMV Early Events";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase"
XP_049844707.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049845792.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049848272.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049833900.1	182	Reactome: R-HSA-4608870;Reactome: R-HSA-5696397;Reactome: R-HSA-3322077;Reactome: R-HSA-6782135;Reactome: R-HSA-6791226;Reactome: R-HSA-195253;Reactome: R-HSA-9615710;Reactome: R-HSA-5693607;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5675482;Reactome: R-HSA-937042;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-6804760;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-5658442;Reactome: R-HSA-1799339;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-8866654;Reactome: R-HSA-917729;Reactome: R-HSA-68949;Reactome: R-HSA-2173795;Reactome: R-HSA-9645460;Reactome: R-HSA-192823;Reactome: R-HSA-2467813;Reactome: R-HSA-182971;Reactome: R-HSA-901032;Reactome: R-HSA-917937;Reactome: R-HSA-9013973;Reactome: R-HSA-3785653;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-174184;Reactome: R-HSA-8875360;Reactome: R-HSA-4641258;Reactome: R-HSA-445989;Reactome: R-HSA-3134975;Reactome: R-HSA-9636383;Reactome: R-HSA-1236382;Reactome: R-HSA-936440;Reactome: R-HSA-168927;Reactome: R-HSA-450302;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-8939236;Reactome: R-HSA-168928;Reactome: R-HSA-382556;Reactome: R-HSA-5654726;Reactome: R-HSA-110314;Reactome: R-HSA-174490;Reactome: R-HSA-8856828;Reactome: R-HSA-5684264;Reactome: R-HSA-936964;Reactome: R-HSA-450321;Reactome: R-HSA-9013507;Reactome: R-HSA-209560;Reactome: R-HSA-2559582;Reactome: R-HSA-174113;Reactome: R-HSA-912631;Reactome: R-HSA-1169091;Reactome: R-HSA-5689896;Reactome: R-HSA-2173791;Reactome: R-HSA-69231;Reactome: R-HSA-4641257;Reactome: R-HSA-5656169;Reactome: R-HSA-8849469;Reactome: R-HSA-9033241;Reactome: R-HSA-5654733;Reactome: R-HSA-8856825;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5655862;Reactome: R-HSA-5689880;Reactome: R-HSA-205043;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-8939902;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-2691232;Reactome: R-HSA-5632684;Reactome: R-HSA-400253;Reactome: R-HSA-975144;Reactome: R-HSA-5358346;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5678895;Reactome: R-HSA-2559580;Reactome: R-HSA-5610785;Reactome: R-HSA-975956;Reactome: R-HSA-110312;Reactome: R-HSA-9613829;Reactome: R-HSA-6782210;Reactome: R-HSA-9646399;Reactome: R-HSA-2672351;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-201681;Reactome: R-HSA-69541;Reactome: R-HSA-8948751;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-174048;Reactome: R-HSA-5685942;Reactome: R-HSA-5607761;Reactome: R-HSA-72764;Reactome: R-HSA-5357956;Reactome: R-HSA-5696394;Reactome: R-HSA-2173796;Reactome: R-HSA-6807004;Reactome: R-HSA-5676590;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1253288;Reactome: R-HSA-8863795;Reactome: R-HSA-9014325;Reactome: R-HSA-72706;Reactome: R-HSA-174154;Reactome: R-HSA-937039;Reactome: R-HSA-8948747;Reactome: R-HSA-1295596;Reactome: R-HSA-110320;Reactome: R-HSA-72649;Reactome: R-HSA-975110;Reactome: R-HSA-5668541;Reactome: R-HSA-1358803;Reactome: R-HSA-2122948;Reactome: R-HSA-8866652;Reactome: R-HSA-179409;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;Reactome: R-HSA-5689877;Reactome: R-HSA-6804757;Reactome: R-HSA-8852276;Reactome: R-HSA-5654732;Reactome: R-HSA-8876493;Reactome: R-HSA-6781827;Reactome: R-HSA-5693565;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-2871837;Reactome: R-HSA-975163;Reactome: R-HSA-5205685;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-2173788;Reactome: R-HSA-2565942;Reactome: R-HSA-5357905;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-9637628;Reactome: R-HSA-168638;Reactome: R-HSA-175474;Reactome: R-HSA-72689;Reactome: R-HSA-4641263;Reactome: R-HSA-975957;Reactome: R-HSA-2894862;Reactome: R-HSA-450408;Reactome: R-HSA-72695;Reactome: R-HSA-2559585;Reactome: R-HSA-162588;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-2979096;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-937041;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-5654727;Reactome: R-HSA-1169408	"Asymmetric localization of PCP proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Glycogen synthesis";"Dual incision in TC-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of beta-catenin by the destruction complex";"Late endosomal microautophagy";"Processing of DNA double-strand break ends";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Regulation of necroptotic cell death";"IRAK2 mediated activation of TAK1 complex";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of TP53 Activity through Methylation";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"Regulation of RAS by GAPs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Orc1 removal from chromatin";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Alpha-protein kinase 1 signaling pathway";"Viral mRNA Translation";"Separation of Sister Chromatids";"EGFR downregulation";"ER Quality Control Compartment (ERQC)";"Iron uptake and transport";"TICAM1-dependent activation of IRF3/IRF7";"Myoclonic epilepsy of Lafora";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of DVL";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of innate immune responses to cytosolic DNA";"Prevention of phagosomal-lysosomal fusion";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"activated TAK1 mediates p38 MAPK activation";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ABC-family proteins mediated transport";"Negative regulation of FGFR1 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Membrane binding and targetting of GAG proteins";"Clathrin-mediated endocytosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NF-kB is activated and signals survival";"Senescence-Associated Secretory Phenotype (SASP)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of signaling by CBL";"Activation of NF-kappaB in B cells";"Ovarian tumor domain proteases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Cyclin D associated events in G1";"Degradation of AXIN";"Termination of translesion DNA synthesis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Peroxisomal protein import";"Negative regulation of FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Translesion synthesis by POLK";"Ub-specific processing proteases";"NRIF signals cell death from the nucleus";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of RUNX2 expression and activity";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Hedgehog 'on' state";"Circadian Clock";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Hedgehog ligand biogenesis";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Defective CFTR causes cystic fibrosis";"Oxidative Stress Induced Senescence";"GLI3 is processed to GLI3R by the proteasome";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translesion synthesis by REV1";"Chaperone Mediated Autophagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Aggrephagy";"Stimuli-sensing channels";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"TCF dependent signaling in response to WNT";"Stabilization of p53";"Regulation of PTEN stability and activity";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"APC/C:Cdc20 mediated degradation of Cyclin B";"HDR through Homologous Recombination (HRR)";"Dectin-1 mediated noncanonical NF-kB signaling";"Eukaryotic Translation Termination";"TNFR1-induced NFkappaB signaling pathway";"DNA Damage Recognition in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of MET activity";"NIK-->noncanonical NF-kB signaling";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Downregulation of ERBB4 signaling";"Downregulation of ERBB2 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"APC/C:Cdc20 mediated degradation of Securin";"IRAK1 recruits IKK complex";"Regulation of PTEN localization";"Spry regulation of FGF signaling";"Translesion Synthesis by POLH";"Translation initiation complex formation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TNFR2 non-canonical NF-kB pathway";"Downregulation of ERBB2:ERBB3 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Josephin domain DUBs";"Regulation of TP53 Degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR3 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downregulation of TGF-beta receptor signaling";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TNFR1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Modulation by Mtb of host immune system";"NOD1/2 Signaling Pathway";"Assembly Of The HIV Virion";"Formation of a pool of free 40S subunits";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Formation of the ternary complex, and subsequently, the 43S complex";"Oncogene Induced Senescence";"Budding and maturation of HIV virion";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"IKK complex recruitment mediated by RIP1";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR2 signaling";"ISG15 antiviral mechanism"
XP_049863805.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049855634.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049835841.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049855044.1	6	KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049827738.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049863608.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049837108.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049863566.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049837955.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049827349.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049847004.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049852619.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049828846.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049844366.1	18	Reactome: R-HSA-70268;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-71064;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4	"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine catabolism";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Glycine, serine and threonine metabolism";"Lysine degradation";"Glycolysis / Gluconeogenesis"
XP_049831855.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049843765.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049848478.1	7	Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-983170	"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049844265.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834389.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049830970.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049854007.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049858093.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_049830382.1	56	Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590	"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling"
XP_049851817.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-201722;Reactome: R-HSA-8936459	"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049835260.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049849627.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049853623.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049844225.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049827520.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049836438.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049851792.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049862467.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049836987.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745	"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_049860547.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049831317.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049833055.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_049846702.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049853031.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049851853.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049849423.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049830965.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049837860.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049829752.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049828157.1	13	KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;Reactome: R-HSA-196757	"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines"
XP_049842919.1	4	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049857997.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_049834915.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168271	"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_049852940.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049859019.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049864149.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_049833570.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049852758.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049851402.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049854002.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049853598.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049829578.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049837476.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049859260.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049863724.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049837354.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049839333.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_049838803.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049855881.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049864190.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049838377.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049852464.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049849758.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_049864737.1	24	Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-202040	"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G-protein activation"
XP_049850155.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049858117.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049839914.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049854769.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049847045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049854572.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049835355.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049850405.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049828119.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049851109.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049856919.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049864160.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049847419.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049834351.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049838362.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049836548.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049837882.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049827082.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049838579.1	12	KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;Reactome: R-HSA-173599	"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate"
XP_049830750.1	13	Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654	"Aggrephagy";"Ovarian tumor domain proteases";"HSF1 activation";"Josephin domain DUBs";"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049862758.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049847492.1	16	Reactome: R-HSA-194840;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-512988	"Rho GTPase cycle";"RET signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_049849319.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791;Reactome: R-HSA-500753;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5	"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism"
XP_049848286.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049860186.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049847617.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049839387.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049861362.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049827785.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049854954.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049829307.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049846874.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049864269.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049857032.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_049833373.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049864400.1	8	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049828355.1	12	Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1	"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection"
XP_049851219.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049828787.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049860714.1	13	KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)"
XP_049854562.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049847684.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049832417.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049857816.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049835947.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049857769.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049859357.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049830872.1	14	Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-110312	"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1"
XP_049845383.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_049838600.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049830829.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-5123;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383	"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_049834481.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049832185.1	13	KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis"
XP_049838630.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049854919.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826895.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2	"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"T cell receptor signaling pathway"
XP_049844039.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049829225.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049832481.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049845491.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049844329.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-186763	"MET activates RAP1 and RAC1";"MET receptor recycling";"Regulation of signaling by CBL";"Downstream signal transduction"
XP_049859182.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049862072.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049841578.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049845050.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049844359.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049862909.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049826902.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-525793	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Myogenesis"
XP_049831170.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049841103.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation"
XP_049830594.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049828890.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049829703.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049862702.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049842187.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903	"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy"
XP_049838425.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049851052.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049848815.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049832735.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049841045.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049827216.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_049861107.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049839205.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049829775.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism"
XP_049841522.1	5	KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway"
XP_049839427.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838899.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049857596.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136	"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049846271.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049833228.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859	"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"snRNP Assembly"
XP_049837477.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049852245.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049845985.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049841688.1	8	KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;MetaCyc: PWY-7980	"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ATP biosynthesis"
XP_049859685.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)"
XP_049843325.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_049855875.1	5	KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4	"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Geraniol degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_049839893.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049861359.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049856493.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049829417.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049840565.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049849704.1	9	MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;Reactome: R-HSA-70171	"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis"
XP_049860598.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049851244.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049833046.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049848348.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049829818.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049847191.1	4	Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829	"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049833321.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049828951.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049863975.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049849050.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049841989.1	17	Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-1834949;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-3270619;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"IRF3-mediated induction of type I IFN";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
XP_049837591.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_049848310.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species"
XP_049833376.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_049860515.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049849852.1	5	MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049844188.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049829981.1	7	KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134	"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV"
XP_049854768.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168	"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049851530.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049851019.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049832619.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049839590.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049863406.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049833681.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049859051.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049848553.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049842494.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049838884.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049835470.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049851292.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049857777.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049845032.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049835912.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049860626.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049828927.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049829702.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049851302.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049850053.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling"
XP_049853675.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049852327.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049830128.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049840243.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_049837516.1	5	KEGG: 00983+2.4.2.4;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.4;MetaCyc: PWY-7181;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine catabolism"
XP_049836646.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049827947.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049836154.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_049850576.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049862847.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes"
XP_049842868.1	7	Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_049838785.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049850164.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049856372.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049854334.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049855242.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434	"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049828460.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049856877.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049855633.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049862874.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049843321.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049839395.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946	"RAF activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants"
XP_049832181.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828066.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049846076.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049840046.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049835872.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049838415.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Degradation of the extracellular matrix";"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049843498.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862	"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049860599.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049851143.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049845421.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049862665.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049829134.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049840053.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049858759.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation"
XP_049841986.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_049827313.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049856883.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049861517.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049842044.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049860798.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_049845305.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049832077.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049836283.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049838434.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049859582.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834096.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049858066.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049859158.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049854566.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049843572.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049862469.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049829817.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049860108.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049836018.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_049853216.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049835777.1	13	Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427	"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation"
XP_049837284.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049860823.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049849629.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049838770.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049858591.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049850525.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049857715.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049831589.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049854291.1	13	Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-450302	"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation"
XP_049835907.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049833068.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049833871.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049859156.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049838794.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049827837.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_049831504.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_049844802.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420	"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi"
XP_049839227.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_049853705.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
YP_010417146.1	7	Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-5083;Reactome: R-HSA-6799198	"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis"
XP_049829468.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049840264.1	12	MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
XP_049862617.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049829836.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_049856823.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049860365.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049846736.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-1187;MetaCyc: PWY-601;MetaCyc: PWY-6936;Reactome: R-HSA-71240;MetaCyc: PWY-2821	"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine"
XP_049839231.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049849207.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049829344.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049847610.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969	"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina"
XP_049862525.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852285.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049837100.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049857765.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049830783.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049862407.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049837150.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049842004.1	5	Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-9627069	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity"
XP_049853640.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049840733.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049856196.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_049852657.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049846558.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049849341.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049858924.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049830380.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049830163.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049833195.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049833045.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049849510.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)"
XP_049829484.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049864442.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049833885.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049853142.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049845636.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049850337.1	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping"
XP_049858933.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049843070.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049838698.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049833246.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport"
XP_049861066.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049862396.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835285.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049852720.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049846540.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049831803.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049847659.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049840266.1	12	MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263	"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis"
XP_049859411.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_049863094.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049828832.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049842887.1	9	MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049827021.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049828864.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049836138.1	4	MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-5691	"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin I"
XP_049855625.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049828357.1	12	Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"NRAGE signals death through JNK";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049849285.1	3	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049836545.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049860966.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049831316.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848819.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218	"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_049863795.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049848733.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-2559582	"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)"
XP_049837329.1	4	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis"
XP_049842000.1	9	Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_049851254.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049846588.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049853037.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049843075.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049864240.1	9	MetaCyc: PWY-6471;KEGG: 00513+2.4.1.141;Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6470;MetaCyc: PWY-5265	"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Various types of N-glycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)"
XP_049837134.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049864557.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049834699.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049833125.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049864096.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049852715.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049857309.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049853825.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049858947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049837658.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049841284.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049843566.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049839101.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049848880.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049838371.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049828531.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_049854659.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_049850726.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-168276	"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways"
XP_049851000.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049850145.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049848558.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_049831789.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049864475.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049852753.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_049837927.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049839143.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049827675.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_049827209.1	3	Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_049849433.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049856811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853062.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049854691.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049850510.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049827312.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_049856905.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049852199.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049849925.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_049852406.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049837205.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049838723.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049851711.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049840173.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049848240.1	7	KEGG: 00620+4.1.1.49;KEGG: 00020+4.1.1.49;KEGG: 00710+4.1.1.49;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.49;MetaCyc: PWY-7117;MetaCyc: PWY-561	"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_049829969.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049848983.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049848150.1	18	KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117	"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Tyrosine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_049834680.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049829058.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049851958.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049850839.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049845672.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049842992.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049839196.1	5	MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695	"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway";"Neutrophil degranulation"
XP_049831261.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_049857089.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049840164.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049847667.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049848000.1	13	MetaCyc: PWY-7112;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis"
XP_049848032.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049864122.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049854196.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049838627.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049839271.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_049852041.1	8	KEGG: 00521+5.5.1.4;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6664	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis"
XP_049861944.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049840305.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049864276.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049828885.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049852235.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049859238.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049844764.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049830817.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049864735.1	24	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-400042	"G alpha (q) signalling events";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_049832899.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049838624.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049838564.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049848948.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049854476.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049845571.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Activation of RAC1";"PI3K-Akt signaling pathway"
XP_049864417.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling"
XP_049845110.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049835917.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049857935.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049842624.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049833295.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787	"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state"
XP_049844226.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049850730.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_049850847.1	4	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_049849212.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049862672.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling"
XP_049857085.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049831241.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049849653.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Interleukin-1 signaling"
XP_049858061.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049837492.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049843154.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049864150.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049851928.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481	"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints"
XP_049854926.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049838900.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049858068.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049828813.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049860715.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000	"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation"
XP_049854757.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_049844541.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049831799.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049837873.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049846698.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049832438.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_049859419.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049837721.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049856391.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049862041.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049841985.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_049848832.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049831616.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_049854603.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049860646.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932	"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB"
XP_049831406.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049860806.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049840832.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049863262.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049853599.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049851187.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_049860613.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_049853684.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049849421.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049848232.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049844560.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049833445.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049848473.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-69166	"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate"
XP_049839560.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049853857.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049861544.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
YP_010417153.1	7	Reactome: R-HSA-6799198;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-4302;Reactome: R-HSA-611105	"Complex I biogenesis";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport"
XP_049863816.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049840780.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049831919.1	10	Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-6317	"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)"
XP_049828401.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291	"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049861360.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049852251.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049843315.1	24	Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-392170	"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G-protein activation";"ADP signalling through P2Y purinoceptor 12"
XP_049829687.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049846645.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049847388.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
YP_010417149.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049858992.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-912446	"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Meiotic recombination"
XP_049863707.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049862453.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049845503.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_049829146.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049858041.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049844097.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049854863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049849284.1	3	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049864105.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049844001.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049857898.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049828741.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049863987.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049855685.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049848752.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049856051.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-167590	"Blockage of phagosome acidification";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD4 Down-regulation"
XP_049858028.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049863980.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049857992.1	5	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_049832877.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049861813.1	14	KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-6453;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4	"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049844916.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049831598.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049828245.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049845482.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Propanoate metabolism"
XP_049848214.1	4	KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism"
XP_049831421.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049831327.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049852138.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_049846554.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049844709.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049852771.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049834708.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049838784.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049841981.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049829406.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049836616.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049827475.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049832743.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049832600.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049833074.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852172.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA"
XP_049840086.1	7	MetaCyc: PWY-7886;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7818;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Glycerophospholipid metabolism"
XP_049847657.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049848637.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049852864.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_049859971.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049831923.1	10	MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-7344	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis"
XP_049859800.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049860560.1	18	KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1	"Tyrosine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis"
XP_049837862.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049848161.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049847063.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049846628.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049838426.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049826937.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049854790.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049857373.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049837767.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049833888.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_049853523.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049833406.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism"
XP_049840870.1	29	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-174437	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand"
XP_049853051.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049831898.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049848230.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049860546.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_049862620.1	16	KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-2221;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11	"Methane metabolism";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_049860553.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants"
XP_049831103.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049848825.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049838261.1	10	MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_049827895.1	8	MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation"
XP_049848189.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049852173.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"Neutrophil degranulation"
XP_049844798.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049837857.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049827102.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049840272.1	12	MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
XP_049828656.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049834165.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049845819.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049861583.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049844582.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin metabolism"
XP_049863765.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049855392.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049864691.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049833307.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling"
XP_049850952.1	7	Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Inositol phosphate metabolism"
XP_049858583.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049829461.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049858341.1	5	Reactome: R-HSA-1234174;Reactome: R-HSA-1234158;Reactome: R-HSA-1234176;Reactome: R-HSA-8849473;Reactome: R-HSA-8951664	"Cellular response to hypoxia";"Regulation of gene expression by Hypoxia-inducible Factor";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"PTK6 Expression";"Neddylation"
XP_049861688.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049839258.1	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
XP_049863636.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_049850032.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049830788.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049851280.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_049853277.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049828320.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049861409.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049861181.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049842669.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838200.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049864543.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_049861216.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049858391.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049863071.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859	"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"snRNP Assembly"
XP_049839248.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049829688.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049831346.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425	"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049837123.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049863560.1	10	Reactome: R-HSA-1461957;Reactome: R-HSA-1236974;Reactome: R-HSA-5602498;Reactome: R-HSA-168179;Reactome: R-HSA-9637628;Reactome: R-HSA-5686938;Reactome: R-HSA-166058;Reactome: R-HSA-5603041;Reactome: R-HSA-6798695;Reactome: R-HSA-168188	"Beta defensins";"ER-Phagosome pathway";"MyD88 deficiency (TLR2/4)";"Toll Like Receptor TLR1:TLR2 Cascade";"Modulation by Mtb of host immune system";"Regulation of TLR by endogenous ligand";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"Neutrophil degranulation";"Toll Like Receptor TLR6:TLR2 Cascade"
XP_049838858.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110362	"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair"
XP_049844558.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049860154.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049864366.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049852687.1	9	Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5	"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism"
XP_049844234.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049840176.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049845107.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049859374.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-210744	"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Attenuation phase";"Circadian Clock";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_049836161.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257	"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion"
XP_049859366.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049860213.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049847483.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049842109.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51	"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerolipid metabolism"
XP_049844370.1	18	Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00020+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;MetaCyc: PWY-5084;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-204174;KEGG: 00640+1.8.1.4	"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycine degradation";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Pyruvate metabolism";"Lysine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Propanoate metabolism"
XP_049860299.1	16	MetaCyc: PWY-2221;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-5484	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Methane metabolism";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_049848227.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049854265.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049859641.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049852582.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate"
XP_049851238.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049854571.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049844697.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049838777.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049847878.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049846709.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049845622.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_049847452.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049847683.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049857454.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049830624.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049829842.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049838226.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_049839834.1	10	Reactome: R-HSA-201722;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Formation of the beta-catenin:TCF transactivating complex";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"HATs acetylate histones";"Ub-specific processing proteases";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_049858186.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049857415.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049843830.1	19	Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-428543	"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"Myogenesis";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"EGFR downregulation";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"Inactivation of CDC42 and RAC1"
XP_049829540.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049831272.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4086400	"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"PCP/CE pathway"
XP_049860023.1	33	Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822	"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_049837713.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049852184.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049838541.1	26	Reactome: R-HSA-4615885;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-110314	"SUMOylation of DNA replication proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by REV1";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049845008.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049862424.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862437.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847235.1	19	KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690	"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle II (plants and fungi)"
XP_049845852.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425	"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049835898.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049852300.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_049852834.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049850137.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049862177.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049827503.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049849432.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049844603.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049863797.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049831880.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049842394.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049831329.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049845727.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049834064.1	1	Reactome: R-HSA-193670	"p75NTR negatively regulates cell cycle via SC1"
XP_049853145.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850265.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049844536.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_049830292.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049840157.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_049831870.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049848114.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049853726.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_049855813.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049860008.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049834728.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049862077.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837880.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049862526.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049828614.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049860661.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049857057.1	10	Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_049845871.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-3214847	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones"
XP_049836645.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049830340.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049830201.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions"
XP_049849996.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049853657.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049849922.1	17	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049859543.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049827407.1	7	KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049853238.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049850303.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049828568.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049833289.1	5	MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049827861.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049852161.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049827030.1	6	KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820	"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_049831723.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049835258.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049857412.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049828394.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049852707.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049849245.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease"
XP_049829510.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049852725.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049835790.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_049859708.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049864053.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049854058.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_049836392.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049834510.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049843064.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049844332.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_049831323.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049846549.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-438066	"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049851291.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049838552.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049845103.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049836888.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843408.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049840512.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049858651.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049832074.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049838771.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049834319.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
XP_049851633.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049832283.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049858240.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049832581.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049861187.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665	"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells"
XP_049840235.1	4	KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963	"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_049855391.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844369.1	18	KEGG: 00620+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-6783984;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-70268;MetaCyc: PWY-5084;Reactome: R-HSA-70895;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Propanoate metabolism";"Lysine catabolism";"Glycine degradation";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid"
XP_049838160.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049863625.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049857277.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049842562.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_049858621.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049827779.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049843067.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049860838.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_049844607.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809	"Ion homeostasis";"Ca2+ pathway";"DAG and IP3 signaling";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization"
XP_049846586.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049833227.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049841947.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_049838563.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049838308.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854932.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049857908.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049864212.1	5	MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279	"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)"
XP_049834035.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049853932.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_049852019.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049843594.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049864064.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049838860.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110362	"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair"
XP_049858084.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_049862659.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049859180.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049849462.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049863785.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049843668.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049863388.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049849455.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049835993.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049828712.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049852171.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"Neutrophil degranulation"
XP_049841931.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049858532.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049851797.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049835244.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049860035.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049846014.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049830206.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553	"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs"
XP_049859991.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049827656.1	9	KEGG: 04151+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Cell-extracellular matrix interactions";"Human immunodeficiency virus 1 infection"
XP_049845759.1	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;MetaCyc: PWY-7839	"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis"
XP_049840261.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
XP_049851018.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049830499.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049849072.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049854148.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049834908.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_049830226.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837717.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination"
XP_049852407.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049839908.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049834569.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_049852718.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049831437.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049839543.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049830018.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049834961.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049838707.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049847503.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049831988.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049864147.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049838568.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049844187.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049850160.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049828795.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049849623.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049856756.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049864817.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049863091.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049852706.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049849690.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049833372.1	10	MetaCyc: PWY-7979;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049834290.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_049851336.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049853176.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049862245.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049849279.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049856219.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049857434.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_049857244.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049831532.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049855434.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049852759.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049862527.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049844224.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049862800.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049841170.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049836375.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_049837479.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049856478.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049836366.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049844365.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049856273.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049834913.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049826915.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_049860636.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9617324	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049859363.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049860412.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049828410.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049862821.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049843603.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049864230.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848732.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556	"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport"
XP_049862658.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049839760.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049854451.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049840271.1	12	MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13	"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_049835288.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049851062.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231	"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"HCMV Late Events";"HCMV Early Events";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049840260.1	12	MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049827726.1	5	MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_049847105.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049846004.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049831477.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049861130.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049828278.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049838544.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049828422.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049830681.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499	"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane"
XP_049842224.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049853674.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049862185.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049836251.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174048	"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049832296.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049857901.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049834098.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049852237.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049834902.1	33	Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-73772;Reactome: R-HSA-167160	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_049852401.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049837646.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049849377.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049849240.1	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049840511.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049849419.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_049837054.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049830345.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049864699.1	8	KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis"
XP_049860184.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049844780.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049847825.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049843579.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049864281.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
XP_049848716.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049835484.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049850522.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2"
XP_049827581.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049835252.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049830108.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848410.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049857240.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049851206.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049828667.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_049831788.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049832637.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049841850.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049831624.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049831882.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049861768.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_049827223.1	6	MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118	"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle"
XP_049846400.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-975634	"Clathrin-mediated endocytosis";"Chylomicron assembly";"Platelet sensitization by LDL";"Chylomicron remodeling";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL assembly";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Scavenging by Class B Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport"
XP_049855192.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049860382.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049831190.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049858935.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049850240.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049849178.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049846722.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049855782.1	25	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049862738.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049827831.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049844118.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049837099.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049846372.1	4	Reactome: R-HSA-70921;MetaCyc: PWY-5028;MetaCyc: PWY-5030;KEGG: 00340+4.3.1.3	"Histidine catabolism";"L-histidine degradation II";"L-histidine degradation III";"Histidine metabolism"
XP_049831072.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049844578.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency"
XP_049861159.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_049826922.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049855955.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049859003.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049862830.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049846632.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049858095.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_049835471.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_049829959.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049831600.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049829222.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049850971.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049836624.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049850975.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049828264.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049846691.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_049831764.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049840823.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049840245.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049840171.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049833124.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049859620.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049834068.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_049852238.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379	"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events"
XP_049853920.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_049842181.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903	"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy"
XP_049861418.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049850890.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049828202.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049852337.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049856218.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049841046.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049831166.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049856920.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049852459.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_049853219.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68962	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex"
XP_049864776.1	17	Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176412	"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C"
XP_049833324.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049849496.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_049827234.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049862769.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_049833063.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049830755.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049835530.1	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_049841734.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049850133.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848089.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049856272.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049863081.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049833069.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049857827.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049860509.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_049862697.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049830537.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049836040.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049847331.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049853182.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049832511.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049835450.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049850673.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049857834.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049860717.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049862706.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049857036.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848711.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049849473.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049837322.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049849452.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091	"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells"
XP_049856569.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049859509.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049853858.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049862995.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049837745.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_049842396.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049845138.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049853724.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049829699.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049830896.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049844765.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049832487.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049849477.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049831240.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850461.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation"
XP_049843788.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049863773.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049853852.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049835644.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049848338.1	5	MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049842226.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049833182.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_049846243.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-606279	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Fanconi Anemia Pathway";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049836349.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049858319.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049849045.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049828369.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_049855088.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049846074.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5531	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_049850864.1	11	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_049833463.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049852608.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049830596.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049845872.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-3214847	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones"
XP_049831706.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049844231.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049853715.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400	"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049858045.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism"
XP_049834235.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049854188.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049845080.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_049857002.1	7	MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_049840533.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_049828805.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049844557.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049861913.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049838376.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049847183.1	7	KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-7282	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049840268.1	12	MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)"
XP_049848423.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049833963.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049842342.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049830165.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049842991.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049853683.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049859831.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049849435.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049833244.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049862576.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049864462.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049836484.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_049853937.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049834558.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049834219.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049829215.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_049858356.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049859435.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049852239.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_049851307.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_049847292.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049847185.1	7	KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-7282;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049850029.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_049836147.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049840065.1	3	Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049848506.1	16	MetaCyc: PWY-6797;MetaCyc: PWY-7853;Reactome: R-HSA-156581;Reactome: R-HSA-196741;MetaCyc: PWY-7539;MetaCyc: PWY-6148;MetaCyc: PWY-6147;MetaCyc: PWY-6614;KEGG: 00790+4.1.2.25;Reactome: R-HSA-3359469;Reactome: R-HSA-1474151;KEGG: 00790+2.5.1.15;MetaCyc: PWY-7852;KEGG: 00790+2.7.6.3;Reactome: R-HSA-1614635;Reactome: R-HSA-3359467	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis V (Pyrococcus)";"Methylation";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)";"Tetrahydromethanopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Sulfur amino acid metabolism";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE"
XP_049831856.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049838642.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833180.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049864411.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_049852360.1	29	Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-167200	"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049843080.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049849466.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_049827094.1	15	Reactome: R-HSA-5637810;Reactome: R-HSA-9665247;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-1227986;Reactome: R-HSA-9652282;Reactome: R-HSA-9665250;Reactome: R-HSA-9665251	"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signaling by ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to lapatinib"
XP_049834741.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049863563.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049850647.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049843636.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049826899.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236	"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049827468.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049864561.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049828203.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049853293.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_049837607.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049858357.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049834900.1	33	Reactome: R-HSA-167160;Reactome: R-HSA-69231;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-69656;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-69202;Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-112382	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin D associated events in G1";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_049830846.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049841234.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049863667.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049851473.1	9	KEGG: 00910+1.4.1.2;KEGG: 00250+1.4.1.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7126;Reactome: R-HSA-8964539;KEGG: 00430+1.4.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5022;KEGG: 00220+1.4.1.2	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis IV (engineered)";"Glutamate and glutamine metabolism";"Taurine and hypotaurine metabolism";"Methylaspartate cycle";"4-aminobutanoate degradation V";"Arginine biosynthesis"
XP_049853423.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049831422.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049842147.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-8086;MetaCyc: PWY-6142;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1	"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Pyruvate metabolism"
XP_049853845.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049828530.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_049863231.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049830362.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049830765.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049848424.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049862770.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049851061.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214	"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins"
XP_049861401.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049864433.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism"
XP_049828204.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049832162.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847486.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049835948.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_049833697.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049849977.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_049848341.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049848659.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049848252.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049838407.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049848991.1	4	Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_049864523.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049847470.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049827012.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049838499.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559	"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway"
XP_049834677.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049849620.1	33	MetaCyc: PWY-5079;MetaCyc: PWY-7013;MetaCyc: PWY-5480;KEGG: 00680+1.1.1.284;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5076;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-6871;MetaCyc: PWY-6333;MetaCyc: PWY-7111;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5082;MetaCyc: PWY-5078;MetaCyc: PWY-6313;MetaCyc: PWY-7118;MetaCyc: PWY-3162;MetaCyc: PWY-6587;MetaCyc: PWY-7798;KEGG: 00071+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-1801;KEGG: 00625+1.1.1.1;KEGG: 00982+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5057;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7396	"L-phenylalanine degradation III";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to ethanol I";"Methane metabolism";"Naphthalene degradation";"Noradrenaline and adrenaline degradation";"L-leucine degradation III";"Tyrosine metabolism";"Salidroside biosynthesis";"3-methylbutanol biosynthesis (engineered)";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to isobutanol (engineered)";"Retinol metabolism";"Phenylethanol biosynthesis";"L-methionine degradation III";"L-isoleucine degradation II";"Serotonin degradation";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol III";"Protein S-nitrosylation and denitrosylation";"Fatty acid degradation";"Ethanol oxidation";"Formaldehyde oxidation II (glutathione-dependent)";"Chloroalkane and chloroalkene degradation";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol II";"L-valine degradation II";"alpha-Linolenic acid metabolism";"Butanol and isobutanol biosynthesis (engineered)"
XP_049851366.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049845109.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049852456.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049829777.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6	"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation"
XP_049850491.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049841396.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049844577.1	6	KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;Reactome: R-HSA-196780;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049828554.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_049854193.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049831507.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049858673.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_049832300.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049852708.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049829049.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049864460.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049857931.1	8	Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885	"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins"
XP_049849851.1	7	MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_049862835.1	5	KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_049854505.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate biosynthesis";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"One carbon pool by folate"
XP_049835413.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049828260.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049864551.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_049852611.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_049840050.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828948.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049856470.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049845837.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049849074.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049862896.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II"
XP_049859350.1	17	Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-110314	"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049842220.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049859572.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049845578.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049837517.1	5	KEGG: 00240+2.4.2.4;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.4;MetaCyc: PWY-7181;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine catabolism"
XP_049857573.1	5	KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;Reactome: R-HSA-392154	"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase"
XP_049827314.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy"
XP_049849211.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049852887.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049851961.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049864072.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049829746.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049856907.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049844160.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049863064.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69656	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049860149.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049851930.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049838411.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049836413.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049852073.1	5	KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843	"Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism"
XP_049851401.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049849930.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049853882.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049834095.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049853736.1	1	Reactome: R-HSA-8856825	"Cargo recognition for clathrin-mediated endocytosis"
XP_049854144.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049847854.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_049851294.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection"
XP_049860741.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049833504.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049854546.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049848407.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049855849.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049851174.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation"
XP_049831242.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049830218.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049832070.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049827063.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049853806.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049844561.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049837684.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459	"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049827589.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049852787.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049845677.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049830344.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049837307.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049837676.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_049846882.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_049846278.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049827331.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049853538.1	30	Reactome: R-HSA-2564830;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400	"Cytosolic iron-sulfur cluster assembly";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER"
XP_049854813.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049853212.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049830572.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049856813.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049843077.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049862886.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555	"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events"
XP_049829041.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049848159.1	57	Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684	"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state"
XP_049837122.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049849070.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049838903.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049858101.1	10	MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Galactose metabolism"
XP_049829712.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049860635.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-72086	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping"
XP_049836063.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049849044.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049864036.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049833564.1	10	Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-72731	"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Recycling of eIF2:GDP"
XP_049842091.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049837097.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049852795.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049860600.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_049838725.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-6174	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)"
XP_049853682.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049837848.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049838217.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_049855674.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049835180.1	8	KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7199	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage"
XP_049847017.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049846013.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049831713.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_049838872.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049849796.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049835893.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049864106.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049827789.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049851951.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049838546.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049855903.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049843089.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049854949.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049850575.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049838395.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049830644.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors"
XP_049832079.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049848397.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7721	"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_049831369.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049858269.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049860615.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049833431.1	10	MetaCyc: PWY-7344;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2	"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049858090.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049834662.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_049864621.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049859753.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins"
XP_049831692.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049827829.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049837763.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049831537.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049846090.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049853923.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_049858086.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_049850453.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049837126.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049830905.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049840664.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789	"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Carnitine metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049845910.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864167.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049858071.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049851603.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049852470.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049846282.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049860359.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843851.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049844821.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_049845799.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049862757.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049838548.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049860568.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857118.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049851435.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049859529.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049838638.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049846641.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049856050.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-167590	"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation"
XP_049864582.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_049833203.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049844362.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_049854359.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049830273.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049862056.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_049864237.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049828691.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049839426.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857086.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049856040.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049853430.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification"
XP_049839417.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049844367.1	18	Reactome: R-HSA-5362517;Reactome: R-HSA-70895;MetaCyc: PWY-5084;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-71064;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4	"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Glycine degradation";"Lysine catabolism";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_049849097.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049858313.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049850699.1	6	Reactome: R-HSA-174490;Reactome: R-HSA-983168;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_049854360.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049829759.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049840066.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049853284.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_049843249.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-1169408	"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism"
XP_049864263.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_049862622.1	16	KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11	"Methane metabolism";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis"
XP_049846642.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049844797.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049844515.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049852208.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_049852193.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049836327.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049842227.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049833158.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049855945.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_049853036.1	11	Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049846184.1	14	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_049859415.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_049838256.1	10	MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13	"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism"
XP_049855643.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049860377.1	19	Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-3214858;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RMTs methylate histone arginines";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_049856565.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049843011.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049863013.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Circadian Clock";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049834557.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049864397.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7922	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049832969.1	34	Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-9639288;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-159236	"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amino acids regulate mTORC1";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049850870.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049851398.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049848215.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049836603.1	4	Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583	"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_049856208.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_049848777.1	18	Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_049829755.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049861201.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049854191.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049855320.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049831707.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_049849541.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049851503.1	5	Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation"
XP_049846157.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049837677.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049843606.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049862668.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049862718.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049849489.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-418592	"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1"
XP_049826990.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-168333	"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049848867.1	8	Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_049846584.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049858739.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049851565.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049859595.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049833030.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_049831262.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049849685.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_049845349.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049855961.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049862823.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049842002.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_049860724.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775	"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis"
XP_049833563.1	10	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9648895	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_049837023.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049860791.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049857453.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049863281.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049862938.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049863757.1	52	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76066;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-9018519	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression"
XP_049833411.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049831278.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049851416.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049837267.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_049832992.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049846193.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049854258.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049849000.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049852615.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049828360.1	12	Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840	"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"mTOR signaling pathway";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Rho GTPase cycle"
XP_049842885.1	9	MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-7117	"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_049850253.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049840686.1	25	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Aggrephagy";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049838734.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049827419.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049850613.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110331	"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine"
XP_049859406.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844258.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049851939.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-5659	"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis"
XP_049848746.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049848961.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_049828412.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049845711.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049842188.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL"
XP_049844524.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049846502.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049856210.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049847689.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049849797.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049827557.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049846304.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049835163.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049834911.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049859535.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049841417.1	9	Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism"
XP_049827536.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049842501.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049831987.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049853112.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049847902.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049843410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049856423.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049863978.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049836543.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049826894.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236	"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049845042.1	4	Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism"
XP_049829393.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049829693.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049833320.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049838851.1	7	Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815	"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones"
XP_049848016.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049827834.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049860956.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049847434.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049857304.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049861373.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049850297.1	5	Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-446388	"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_049846565.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049838645.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049858013.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs"
XP_049837608.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049839829.1	7	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-110362	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair"
XP_049836816.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049829337.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049860324.1	12	KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049847459.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6804756	"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation"
XP_049848708.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049863339.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_049848707.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049836613.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049850281.1	5	Reactome: R-HSA-446388;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-194840	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"Rho GTPase cycle"
XP_049854192.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049828243.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049844970.1	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049837985.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049850074.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049829753.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049838416.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049843951.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049847301.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_049831366.1	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_049862674.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833724.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis"
XP_049857928.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_049862218.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049848750.1	13	MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-7254;Reactome: R-HSA-71403	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)"
XP_049859281.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049842551.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049848475.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049839121.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049845850.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049856763.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_049850595.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049841763.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_049848318.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049863364.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049827316.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy"
XP_049862700.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049843009.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_049862594.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049835511.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs"
XP_049858779.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049858435.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049844621.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850894.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049853116.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049848952.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_049840083.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7818	"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_049857230.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049847560.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049830616.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049852757.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049850383.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049862799.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049857363.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049852987.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593	"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity"
XP_049837147.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049845793.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049851461.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049850826.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049863254.1	5	Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185	"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I"
XP_049849344.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049829547.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049848487.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049849539.1	4	Reactome: R-HSA-381426;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDLR internalisation and degradation";"LDL clearance";"Post-translational protein phosphorylation"
XP_049861408.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049857561.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049839274.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_049827081.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049832282.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049847542.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049844426.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049832982.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_049849867.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins"
XP_049863972.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049841654.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049839147.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049847656.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049852349.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049834942.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation"
XP_049845321.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_049831476.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049832921.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049857169.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049851561.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859	"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly"
XP_049837131.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049853496.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049844340.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_049843076.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049832234.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049864291.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049830509.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_049833151.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049830005.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049862395.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049835389.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling"
XP_049857989.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_049849292.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049829776.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574	"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II"
XP_049843068.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049829785.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system"
XP_049841945.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049856063.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049858091.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_049828553.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049859481.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049851237.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049828910.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049833436.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-561	"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_049853021.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049859750.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_049846968.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049842118.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_049839357.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049859346.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049835891.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049862427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844269.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049864603.1	4	MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049847918.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7184;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates"
XP_049849707.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;Reactome: R-HSA-165159	"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"mTOR signalling"
XP_049829913.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049830298.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049848587.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049843105.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_049853211.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_049850331.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049827108.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_049858909.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049858940.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049848910.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049838378.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049830870.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049831105.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049850536.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049837242.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049863799.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049840055.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843052.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-241	"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049850210.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049846230.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_049838428.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049848329.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049863777.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049864361.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049858758.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049841764.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation"
XP_049853837.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049857484.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991	"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions"
XP_049863968.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049835464.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049855364.1	25	Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-381771;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392170	"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (i) signalling events";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12"
XP_049833539.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049854921.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049862875.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049837877.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049855582.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049851918.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424	"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling"
XP_049852226.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049844325.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049831578.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049863856.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-611105	"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport"
XP_049829294.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049844998.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049859194.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049835462.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_049827147.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049844917.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049858087.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_049848371.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_049858683.1	6	MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_049851562.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231	"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049834424.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049847456.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695	"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Neutrophil degranulation"
XP_049845860.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049864231.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049835193.1	17	Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75035	"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Thermogenesis";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_049859473.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_049854555.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049846726.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis"
XP_049849219.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315	"Methylation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol"
XP_049852079.1	5	MetaCyc: PWY-7185;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176	"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis"
XP_049859099.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049837642.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049830685.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049862894.1	9	MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation"
XP_049847814.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049859162.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049835345.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049858838.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_049833958.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_049848783.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049838046.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2894862	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049850429.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049853521.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4"
XP_049837525.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049850709.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049849464.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049853794.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049830533.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049844300.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049859533.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049856482.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838303.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049833520.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049847551.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049833521.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049837454.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049852983.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580	"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence"
XP_049830140.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12	"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis"
XP_049832069.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049838664.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049840270.1	12	MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
XP_049827119.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049858936.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049854560.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049848362.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049827427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049851495.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049841220.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_049833262.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049842003.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_049862602.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049838907.1	42	Reactome: R-HSA-1221632;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-3214847;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-5625886;Reactome: R-HSA-8936459;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-2559586;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-110330;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-5250924	"Meiotic synapsis";"HDMs demethylate histones";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA methylation";"HCMV Late Events";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"DNA Damage/Telomere Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression"
XP_049862420.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848419.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049831883.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049831448.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049857280.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049834227.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049860406.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049849803.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_049844152.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_049857425.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049830191.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049836591.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844686.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049837685.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692	"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity"
XP_049834729.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049832888.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049835956.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049844601.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049841674.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870	"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins"
XP_049859593.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049843634.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049845626.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049834006.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_049842895.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049863240.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049827793.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049851978.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_049838629.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049843953.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049847612.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_049862868.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_049830924.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049851249.1	19	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-3214858;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049845900.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049844138.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_049859447.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049853223.1	17	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Thermogenesis";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Fanconi Anemia Pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_049847507.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049856472.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838134.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049848309.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Protein ubiquitination"
XP_049850920.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049827324.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049833715.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049858717.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049836379.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049848682.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II"
XP_049854778.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049851567.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049861085.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049840736.1	21	Reactome: R-HSA-933543;Reactome: R-HSA-5603027;Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-5357905;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-937041;Reactome: R-HSA-1236974;Reactome: R-HSA-5603029;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-937039;Reactome: R-HSA-1810476;Reactome: R-HSA-5602636;Reactome: R-HSA-5357956;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-1169091;Reactome: R-HSA-168927	"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of TNFR1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"IKK complex recruitment mediated by RIP1";"ER-Phagosome pathway";"IkBA variant leads to EDA-ID";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"IRAK1 recruits IKK complex";"RIP-mediated NFkB activation via ZBP1";"IKBKB deficiency causes SCID";"TNFR1-induced NFkappaB signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells";"TICAM1, RIP1-mediated IKK complex recruitment"
XP_049832609.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049829329.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049850421.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049836541.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_049857238.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049849234.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049837484.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049853467.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_049847106.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049857837.1	12	MetaCyc: PWY-5744;MetaCyc: PWY-5749;MetaCyc: PWY-7854;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7295;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Glyoxylate assimilation";"Itaconate degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"C5-Branched dibasic acid metabolism";"L-arabinose degradation IV";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Pyruvate metabolism";"D-xylose degradation IV";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049830868.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_049856007.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_049831921.1	10	MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-3821;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2	"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism"
XP_049851426.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049864503.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828145.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049848842.1	8	Reactome: R-HSA-70895;MetaCyc: PWY-6661;KEGG: 00790+6.3.2.17;KEGG: 00400+4.1.3.27;MetaCyc: PWY-2161;MetaCyc: PWY-5958;Reactome: R-HSA-196757;KEGG: 00405+4.1.3.27	"Branched-chain amino acid catabolism";"4-hydroxy-2(1H)-quinolone biosynthesis";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate polyglutamylation";"Acridone alkaloid biosynthesis";"Metabolism of folate and pterines";"Phenazine biosynthesis"
XP_049836047.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049832024.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049856832.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049834742.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049835949.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_049842894.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049828073.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049863771.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049848346.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288	"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1"
XP_049854605.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049835466.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049844716.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049857839.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049850580.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049855963.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
XP_049861209.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142	"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"HCMV Late Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins"
XP_049864277.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049830945.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049851649.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049857538.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049843171.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844907.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049852712.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049849913.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049844903.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049862897.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049850157.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049852081.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049860223.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049836363.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049845104.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049829262.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_049850695.1	6	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-983168;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_049836665.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049848217.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049833028.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_049862828.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049844794.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049852658.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049834829.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049857284.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049851716.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049837814.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049848773.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_049838419.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049840739.1	21	Reactome: R-HSA-1236974;Reactome: R-HSA-5603029;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-933543;Reactome: R-HSA-5603027;Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-5357905;Reactome: R-HSA-5684264;Reactome: R-HSA-937041;Reactome: R-HSA-9020702;Reactome: R-HSA-5602636;Reactome: R-HSA-5357956;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-1169091;Reactome: R-HSA-168927;Reactome: R-HSA-2871837;Reactome: R-HSA-937039;Reactome: R-HSA-1810476	"ER-Phagosome pathway";"IkBA variant leads to EDA-ID";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of TNFR1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKK complex recruitment mediated by RIP1";"Interleukin-1 signaling";"IKBKB deficiency causes SCID";"TNFR1-induced NFkappaB signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells";"TICAM1, RIP1-mediated IKK complex recruitment";"FCERI mediated NF-kB activation";"IRAK1 recruits IKK complex";"RIP-mediated NFkB activation via ZBP1"
XP_049832021.1	33	Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75955	"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation"
XP_049833146.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049844101.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049830784.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844520.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049831325.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049850867.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_049857224.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049861179.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049836643.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049848626.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258	"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL"
XP_049842413.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049857824.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049851712.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049848828.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049846313.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049831395.1	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_049847425.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049852911.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049834327.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049846629.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049828209.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049832932.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049840579.1	7	KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI"
XP_049852053.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_049857717.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838684.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049840558.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231	"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production"
XP_049835245.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049861948.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049828210.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-1251985	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"TNF signaling";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4"
XP_049843827.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_049854862.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049852415.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049849426.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049849625.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049851920.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049857917.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049854938.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049827784.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049826928.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049862708.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_049847837.1	17	Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-5651801	"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049862789.1	11	Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;Reactome: R-HSA-111457;Reactome: R-HSA-3299685	"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species"
XP_049834242.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049831761.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735	"beta-Alanine metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis"
XP_049848495.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_049849372.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049864550.1	14	Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049857268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049862298.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049827783.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049845627.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049852719.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049840710.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049848008.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049860837.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049836361.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049859986.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049856582.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049844721.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049862414.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049840258.1	12	MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
XP_049864179.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049860612.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001	"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade"
XP_049835477.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049839894.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049837864.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049844896.1	14	MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161	"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Photorespiration ";"Folate polyglutamylation"
XP_049827590.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049838864.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-5651801	"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049854185.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049839077.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling"
XP_049833260.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049862657.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-189085	"Neutrophil degranulation";"Digestion of dietary carbohydrate"
XP_049850056.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257	"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN"
XP_049834965.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049836988.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_049851819.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049859479.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768	"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049849984.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_049835884.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049841224.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_049835829.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection"
XP_049853859.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049847868.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379	"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events"
XP_049853200.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049861214.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049864229.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049839709.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049859408.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049845134.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049839714.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049841085.1	12	KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism"
XP_049846303.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049829246.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;KEGG: 00230+3.5.2.17;Reactome: R-HSA-975634;MetaCyc: PWY-5691;MetaCyc: PWY-7849	"Neutrophil degranulation";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Purine metabolism";"Retinoid metabolism and transport";"Urate conversion to allantoin I";"Urate conversion to allantoin III"
XP_049838489.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_049853444.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049862034.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049863313.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_049841042.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049844773.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6"
XP_049858185.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049828078.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049836105.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049831874.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497	"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049830691.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049852903.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049835283.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049835228.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049848964.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049829968.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049838901.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049827041.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049827682.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049830502.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049841972.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049835253.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049844495.1	10	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257	"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation"
XP_049848454.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049829711.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049853855.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049830381.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049834328.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049849246.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282	"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049864280.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049854125.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049857148.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049851433.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049838916.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_049838396.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049848201.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_049830291.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049849406.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168	"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049856499.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_049830541.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049864225.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049854920.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049858581.1	5	KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_049859348.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation"
XP_049842858.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049852136.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049861104.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049863669.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049856373.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_049833471.1	6	KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23	"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
XP_049862820.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049837464.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049860500.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049828193.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049834420.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049829488.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049863749.1	6	Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-1489509	"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"DAG and IP3 signaling"
XP_049844192.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049842971.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049837743.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_049849669.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_049845691.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-202433;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation"
XP_049864266.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049864386.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049845081.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049860569.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049864530.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049828110.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049852580.1	6	MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_049852808.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049844942.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049832474.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_049862455.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049838413.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049854151.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049829632.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049849765.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049858351.1	2	Reactome: R-HSA-389957;Reactome: R-HSA-8953750	"Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6"
XP_049829681.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049854340.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049842420.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_049846570.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049860662.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837	"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases"
XP_049847817.1	4	Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism"
XP_049833869.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_049856626.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049850972.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049835344.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049839990.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049850970.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049863889.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1221632	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Meiotic synapsis"
XP_049831601.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049837130.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049851190.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049855380.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049851304.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049857985.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049842813.1	4	Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049846225.1	7	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_049850889.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049837463.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049830586.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049833773.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049851957.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049840488.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049836157.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049842544.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049863804.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049843079.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049844997.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049860629.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-442982	"Interferon gamma signaling";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049841172.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049862834.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049835356.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-390471	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049860786.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848909.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049836373.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_049851368.1	11	KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-882;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-3881;MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-3861	"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Mannitol degradation II"
XP_049840265.1	12	MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway"
XP_049829858.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049839354.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049859163.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049852534.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-975634	"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport"
XP_049850734.1	10	KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10	"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Butanoate metabolism"
XP_049828768.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049861983.1	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_049838846.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049844753.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049828598.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049838139.1	14	MetaCyc: PWY-5103;MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5078;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42	"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-leucine degradation III";"Glucosinolate biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism"
XP_049852399.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049861653.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049842537.1	15	KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049852295.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_049833774.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049852991.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049828207.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049854242.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation"
XP_049849321.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049857814.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049852886.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049854272.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049838542.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_049840665.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425	"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"Pyruvate metabolism";"Carnitine metabolism"
XP_049835839.1	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_049830828.1	13	MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7141;MetaCyc: PWY-7659	"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis"
XP_049858815.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_049850702.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_049853303.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848388.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049839879.1	10	MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)"
XP_049849450.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049850767.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049847553.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049827473.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049830989.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049830925.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049849699.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049840562.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049840825.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828931.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049850530.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312	"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1"
XP_049827781.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes"
XP_049827673.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049830279.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049838196.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049854958.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_049829253.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049862772.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049848992.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844952.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049848360.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049827515.1	5	KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556	"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"ROS and RNS production in phagocytes"
XP_049843567.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049857900.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049859043.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854	"HCMV Late Events";"HCMV Early Events";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly"
XP_049840679.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049863048.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049839957.1	7	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_049832627.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049827499.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049856876.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049861341.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049831644.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049839855.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049850793.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049862734.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049861674.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049852818.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049849688.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway"
XP_049829266.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049857413.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049835460.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_049853493.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049834167.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049846222.1	7	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_049839142.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049844497.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation";"PI3K-Akt signaling pathway"
XP_049831135.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049863772.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049835793.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_049844870.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049831355.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049852011.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"UCH proteinases";"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_049833245.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049841462.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049852159.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049859053.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049831891.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049851630.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049852530.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049831660.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK"
XP_049848971.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049845343.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049831873.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9646399	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy"
XP_049862014.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_049827421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049834698.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_049847616.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049834734.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049859713.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049862720.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_049858094.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria"
XP_049832081.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049857287.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049851285.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
XP_049849241.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_049852455.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049861496.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049864081.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049848431.1	5	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-196819;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Vitamin B1 (thiamin) metabolism";"mRNA Capping"
XP_049835807.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_049847102.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049859377.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568	"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"PPARA activates gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Attenuation phase"
XP_049852036.1	29	Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804757;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6803204;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-69541;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-6804760	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Degradation";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"Autodegradation of the E3 ubiquitin ligase COP1";"Stabilization of p53";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"mTOR signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"Relaxin signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Methylation"
XP_049848897.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049834101.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049845609.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049860832.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049833402.1	4	MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism"
XP_049844694.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049846035.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049840567.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049851173.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049861529.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049849633.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5651801	"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049841048.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-110320	"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH"
XP_049837390.1	6	KEGG: 04070+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism"
XP_049854928.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049863204.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049855079.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049860490.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049837617.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049831728.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049829694.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049838543.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847	"UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones"
XP_049848635.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049830990.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049829326.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049845241.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049862748.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_049830503.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049829778.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7338;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6	"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation"
XP_049862994.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049862888.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (z) signalling events"
XP_049833614.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049858931.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049853060.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049828266.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049861009.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049842937.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism"
XP_049847306.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049835672.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049860506.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049848372.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049830647.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049852593.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049838290.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_049835243.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049838412.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049831431.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049864246.1	12	KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133	"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis"
XP_049852924.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049859744.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049836006.1	22	MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-7726;MetaCyc: PWY-7053;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-6958;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_049831159.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049831741.1	13	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-7112	"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification"
XP_049834686.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049839421.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049854855.1	9	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049849055.1	5	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism"
XP_049858217.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049842591.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049846897.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-2029482	"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation"
XP_049829967.1	13	Reactome: R-HSA-156590;MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18	"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes"
XP_049858636.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049858467.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049847505.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_049840687.1	25	Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins"
XP_049847955.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049847240.1	19	KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5392;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5538	"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI"
XP_049849586.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049851224.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159236	"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049827224.1	6	MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3	"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerophospholipid metabolism"
XP_049830690.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049852223.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049842564.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_049855959.1	6	MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166;MetaCyc: PWY-7817;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG"
XP_049843964.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049864101.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049862228.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049831013.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation"
XP_049840532.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049842873.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490	"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation"
XP_049860191.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049834750.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049863278.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049845610.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049839729.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049861099.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_049852756.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049859433.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049838418.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049835480.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049835445.1	14	Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_049832839.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049830505.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049833089.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049863817.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049840303.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049863605.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049848607.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049863930.1	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049853731.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049841582.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049860162.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844609.1	13	Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-5607763	"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"DAG and IP3 signaling";"Ca2+ pathway";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_049852221.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049844372.1	7	KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-7221;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Purine metabolism";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis"
XP_049848813.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049858466.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049844908.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049848508.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049851710.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049849700.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049864048.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049835878.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049827940.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097	"Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway"
XP_049852711.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049848396.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383	"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_049838133.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049847199.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049835282.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049860151.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049842708.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049848155.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049849887.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049828685.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_049828406.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574	"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II"
XP_049844872.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_049849550.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733	"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_049853627.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049844203.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_049845490.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049859422.1	19	Reactome: R-HSA-72695;Reactome: R-HSA-3214858;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Formation of the ternary complex, and subsequently, the 43S complex";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Protein methylation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049831139.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049840169.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049833446.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_049829933.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049828362.1	12	Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840	"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Rho GTPase cycle"
XP_049831298.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049831772.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049851234.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_049835794.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049830518.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049830083.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
XP_049848608.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049860312.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049836378.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049843023.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049830699.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049847325.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049830666.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_049850974.1	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_049852822.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049846029.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049838420.1	3	Reactome: R-HSA-2129379;Reactome: R-HSA-1566948;Reactome: R-HSA-1474228	"Molecules associated with elastic fibres";"Elastic fibre formation";"Degradation of the extracellular matrix"
XP_049837884.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049830619.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049830301.1	12	MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_049846037.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049856211.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049841738.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049860819.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049855629.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049857788.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049850292.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049830517.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049829513.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049854198.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049848039.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049860282.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049849242.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049832563.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049849061.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049850874.1	10	KEGG: 04070+2.7.1.159;MetaCyc: PWY-6362;MetaCyc: PWY-4661;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-6554;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"
XP_049829419.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-389977	"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway"
XP_049831411.1	21	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049847936.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049859908.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828268.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049835103.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049844295.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049857105.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049851707.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049830818.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049863066.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_049839389.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049852820.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049857349.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049852777.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049853186.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049863386.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_049855052.1	6	MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165	"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049844941.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049855639.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049863796.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049859532.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049863750.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049853061.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049843598.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049835268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049863815.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049852536.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049840782.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049833459.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049838258.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2	"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism"
XP_049862419.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049863793.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049859068.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049841061.1	6	Reactome: R-HSA-71336;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1	"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms"
XP_049836783.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049852268.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_049856059.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049843050.1	5	KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage"
XP_049837475.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049842767.1	8	Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-8941284;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346	"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Activation of SMO";"Hedgehog 'on' state";"RUNX2 regulates chondrocyte maturation";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis"
XP_049831110.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049842411.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049837886.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049849275.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049834107.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049828760.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_049841979.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049849921.1	17	Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_049840480.1	5	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049839779.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049852586.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_049851287.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049861326.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049863242.1	9	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway"
XP_049855368.1	1	Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_049860991.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049833217.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049846033.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049846977.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049862872.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049863800.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049837022.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049850770.1	4	KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;MetaCyc: PWY-7927;Reactome: R-HSA-1614558	"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)";"Degradation of cysteine and homocysteine"
XP_049831367.1	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_049850505.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049835867.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049846344.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049859235.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049829252.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049851962.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049848987.1	11	MetaCyc: PWY-6317;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;Reactome: R-HSA-191273;MetaCyc: PWY-3821;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Cholesterol biosynthesis";"D-galactose detoxification";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Galactose metabolism"
XP_049847815.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049862428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049844277.1	11	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049850735.1	10	MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922	"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I"
XP_049827880.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049850457.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_049838741.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049831587.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049848936.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049859157.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049838550.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones"
XP_049833768.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049862522.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049857160.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049859819.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_049858120.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049852934.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977	"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway"
XP_049830032.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049845839.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049861196.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049847186.1	6	KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_049853727.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049849332.1	11	KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-1632852	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Macroautophagy"
XP_049846693.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049846085.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049843752.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660	"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase activating pathway"
XP_049832689.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049860972.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049853218.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_049827469.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302	"CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome"
XP_049860331.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049829521.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049864502.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049856634.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049856274.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049862408.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049826873.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049830964.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049827718.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism"
XP_049840206.1	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_049852838.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_049862466.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049828984.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;Reactome: R-HSA-6798695	"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation"
XP_049844768.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049832985.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049863780.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049854814.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049854868.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049863794.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049853621.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049847384.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049850488.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049837249.1	5	Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049849702.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_049850831.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_049860366.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049829489.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049844717.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049845788.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049849663.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049835859.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049841173.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049830355.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049827423.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049863703.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049859476.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049852265.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_049843583.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049831778.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049827464.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_049854363.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049860582.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049863057.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049842219.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049838888.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848616.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049831643.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Cyclin D associated events in G1";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_049849261.1	7	MetaCyc: PWY-6969;MetaCyc: PWY-7295;MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7854;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV";"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Pyruvate metabolism";"Chitin degradation to ethanol"
XP_049833842.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049827778.1	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_049834640.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049830416.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049850086.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049830976.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049850892.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049863323.1	31	MetaCyc: PWY-5142;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-4381;MetaCyc: PWY-8049;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-8012;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-6113;Reactome: R-HSA-163765	"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression"
XP_049844038.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049849961.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049838387.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049834164.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_049861033.1	13	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism"
XP_049836365.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049861300.1	10	MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-7198;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_049859252.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_049838365.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049834754.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049864575.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_049849071.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049849340.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049844202.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049835181.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049858119.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049845908.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049861034.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101	"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation"
XP_049864526.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049863383.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049853575.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049857597.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)"
XP_049845763.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049850359.1	6	Reactome: R-HSA-983231;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"Factors involved in megakaryocyte development and platelet production";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049849951.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049845304.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049836352.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049856229.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049858427.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049830271.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049828279.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049850404.1	5	KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049836278.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049852581.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049831802.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049839182.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049837067.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049840289.1	5	Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Neutrophil degranulation";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_049837716.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049839150.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7411	"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_049849204.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844444.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049836766.1	9	Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism"
XP_049833538.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049838738.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049850584.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049864247.1	12	MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672	"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation"
XP_049828249.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049840708.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049852858.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049830360.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049840743.1	14	Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-205043	"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus"
XP_049858330.1	7	Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine"
XP_049864432.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726	"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049836290.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_049843591.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049849185.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049852774.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049842979.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049845117.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_049843562.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049843013.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049830571.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049833148.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049852476.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049828199.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049832179.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843801.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049843560.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049853529.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049848922.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049861032.1	13	Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822	"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Keratan sulfate degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)"
XP_049833759.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-432722	"COPI-mediated anterograde transport";"Golgi Associated Vesicle Biogenesis"
XP_049850146.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049850881.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049827340.1	2	Reactome: R-HSA-210747;Reactome: R-HSA-210745	"Regulation of gene expression in early pancreatic precursor cells";"Regulation of gene expression in beta cells"
XP_049827004.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049861378.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555	"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events"
XP_049859686.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049848219.1	182	Reactome: R-HSA-3785653;Reactome: R-HSA-9013973;Reactome: R-HSA-917937;Reactome: R-HSA-901032;Reactome: R-HSA-182971;Reactome: R-HSA-1236382;Reactome: R-HSA-9636383;Reactome: R-HSA-445989;Reactome: R-HSA-3134975;Reactome: R-HSA-4641258;Reactome: R-HSA-8875360;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-180585;Reactome: R-HSA-937042;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5675482;Reactome: R-HSA-5693607;Reactome: R-HSA-9615710;Reactome: R-HSA-6791226;Reactome: R-HSA-195253;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-5696397;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-192823;Reactome: R-HSA-9645460;Reactome: R-HSA-2173795;Reactome: R-HSA-68949;Reactome: R-HSA-917729;Reactome: R-HSA-8866654;Reactome: R-HSA-9020702;Reactome: R-HSA-5696395;Reactome: R-HSA-1799339;Reactome: R-HSA-5658442;Reactome: R-HSA-209543;Reactome: R-HSA-5675221;Reactome: R-HSA-9604323;Reactome: R-HSA-6804760;Reactome: R-HSA-8854050;Reactome: R-HSA-5654733;Reactome: R-HSA-9033241;Reactome: R-HSA-8849469;Reactome: R-HSA-5656169;Reactome: R-HSA-4641257;Reactome: R-HSA-69231;Reactome: R-HSA-2173791;Reactome: R-HSA-5689896;Reactome: R-HSA-1169091;Reactome: R-HSA-912631;Reactome: R-HSA-2691232;Reactome: R-HSA-6783310;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-156827;Reactome: R-HSA-205043;Reactome: R-HSA-2408557;Reactome: R-HSA-5689880;Reactome: R-HSA-5655862;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-382556;Reactome: R-HSA-168928;Reactome: R-HSA-8939236;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-450302;Reactome: R-HSA-168927;Reactome: R-HSA-936440;Reactome: R-HSA-174113;Reactome: R-HSA-2559582;Reactome: R-HSA-209560;Reactome: R-HSA-9013507;Reactome: R-HSA-450321;Reactome: R-HSA-936964;Reactome: R-HSA-5684264;Reactome: R-HSA-8856828;Reactome: R-HSA-174490;Reactome: R-HSA-110314;Reactome: R-HSA-8948747;Reactome: R-HSA-937039;Reactome: R-HSA-174154;Reactome: R-HSA-72706;Reactome: R-HSA-9014325;Reactome: R-HSA-8863795;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-5676590;Reactome: R-HSA-1253288;Reactome: R-HSA-6807004;Reactome: R-HSA-2173796;Reactome: R-HSA-5696394;Reactome: R-HSA-5357956;Reactome: R-HSA-72764;Reactome: R-HSA-5607761;Reactome: R-HSA-174048;Reactome: R-HSA-5685942;Reactome: R-HSA-2122948;Reactome: R-HSA-1358803;Reactome: R-HSA-5668541;Reactome: R-HSA-72649;Reactome: R-HSA-975110;Reactome: R-HSA-110320;Reactome: R-HSA-1295596;Reactome: R-HSA-2559580;Reactome: R-HSA-5678895;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5358346;Reactome: R-HSA-975144;Reactome: R-HSA-400253;Reactome: R-HSA-5632684;Reactome: R-HSA-977225;Reactome: R-HSA-69541;Reactome: R-HSA-8948751;Reactome: R-HSA-2644606;Reactome: R-HSA-201681;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2672351;Reactome: R-HSA-1236974;Reactome: R-HSA-9646399;Reactome: R-HSA-6782210;Reactome: R-HSA-9613829;Reactome: R-HSA-110312;Reactome: R-HSA-5610785;Reactome: R-HSA-975956;Reactome: R-HSA-2559585;Reactome: R-HSA-72695;Reactome: R-HSA-162588;Reactome: R-HSA-2894862;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-4641263;Reactome: R-HSA-72689;Reactome: R-HSA-175474;Reactome: R-HSA-168638;Reactome: R-HSA-9637628;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-1169408;Reactome: R-HSA-983168;Reactome: R-HSA-5654727;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-937041;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2979096;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-6781827;Reactome: R-HSA-5693565;Reactome: R-HSA-5362768;Reactome: R-HSA-8876493;Reactome: R-HSA-5654732;Reactome: R-HSA-8852276;Reactome: R-HSA-6804757;Reactome: R-HSA-5689877;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-179409;Reactome: R-HSA-8866652;Reactome: R-HSA-2565942;Reactome: R-HSA-5357905;Reactome: R-HSA-2173788;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5205685;Reactome: R-HSA-975163	"Myoclonic epilepsy of Lafora";"TICAM1-dependent activation of IRF3/IRF7";"Iron uptake and transport";"ER Quality Control Compartment (ERQC)";"EGFR downregulation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Prevention of phagosomal-lysosomal fusion";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of innate immune responses to cytosolic DNA";"Degradation of DVL";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Vif-mediated degradation of APOBEC3G";"IRAK2 mediated activation of TAK1 complex";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Regulation of necroptotic cell death";"Processing of DNA double-strand break ends";"Late endosomal microautophagy";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of beta-catenin by the destruction complex";"Dual incision in TC-NER";"Glycogen synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Viral mRNA Translation";"Alpha-protein kinase 1 signaling pathway";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Orc1 removal from chromatin";"Endosomal Sorting Complex Required For Transport (ESCRT)";"E3 ubiquitin ligases ubiquitinate target proteins";"Interleukin-1 signaling";"Formation of Incision Complex in GG-NER";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of RAS by GAPs";"p75NTR recruits signalling complexes";"Negative regulation of MAPK pathway";"Negative regulation of NOTCH4 signaling";"Regulation of TP53 Activity through Methylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of FGFR4 signaling";"Peroxisomal protein import";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Termination of translesion DNA synthesis";"Degradation of AXIN";"Cyclin D associated events in G1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Ovarian tumor domain proteases";"Activation of NF-kappaB in B cells";"Regulation of signaling by CBL";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Fanconi Anemia Pathway";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"L13a-mediated translational silencing of Ceruloplasmin expression";"NRIF signals cell death from the nucleus";"Selenocysteine synthesis";"Ub-specific processing proteases";"Translesion synthesis by POLK";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"ABC-family proteins mediated transport";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"activated TAK1 mediates p38 MAPK activation";"TICAM1, RIP1-mediated IKK complex recruitment";"Negative regulators of DDX58/IFIH1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Senescence-Associated Secretory Phenotype (SASP)";"NF-kB is activated and signals survival";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Clathrin-mediated endocytosis";"Membrane binding and targetting of GAG proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PTEN localization";"IRAK1 recruits IKK complex";"APC/C:Cdc20 mediated degradation of Securin";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of ERBB2 signaling";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"Negative regulation of MET activity";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"DNA Damage Recognition in GG-NER";"TNFR1-induced NFkappaB signaling pathway";"Eukaryotic Translation Termination";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"HDR through Homologous Recombination (HRR)";"Activated NOTCH1 Transmits Signal to the Nucleus";"Downregulation of ERBB2:ERBB3 signaling";"TNFR2 non-canonical NF-kB pathway";"Translation initiation complex formation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Translesion Synthesis by POLH";"Spry regulation of FGF signaling";"Oxidative Stress Induced Senescence";"Defective CFTR causes cystic fibrosis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Hedgehog ligand biogenesis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Circadian Clock";"Hedgehog 'on' state";"Amyloid fiber formation";"Stabilization of p53";"Regulation of PTEN stability and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TCF dependent signaling in response to WNT";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Stimuli-sensing channels";"ER-Phagosome pathway";"Aggrephagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Chaperone Mediated Autophagy";"Translesion synthesis by REV1";"GLI3 is processed to GLI3R by the proteasome";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Oncogene Induced Senescence";"Formation of the ternary complex, and subsequently, the 43S complex";"Budding and maturation of HIV virion";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of FZD by ubiquitination";"Formation of a pool of free 40S subunits";"Assembly Of The HIV Virion";"NOD1/2 Signaling Pathway";"Modulation by Mtb of host immune system";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"ISG15 antiviral mechanism";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR2 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"IKK complex recruitment mediated by RIP1";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"InlA-mediated entry of Listeria monocytogenes into host cells";"Negative regulation of FGFR3 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of TP53 Degradation";"Josephin domain DUBs";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC-Cdc20 mediated degradation of Nek2A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TNFR1 signaling";"Downregulation of TGF-beta receptor signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Pink/Parkin Mediated Mitophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_049833766.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049832603.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049840683.1	25	Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-380270;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Kinesins";"Recruitment of mitotic centrosome proteins and complexes";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs"
XP_049852913.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049850819.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049864100.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049850677.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049833042.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049854239.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049850412.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_049858623.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049832443.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378	"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling"
XP_049860601.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_049864697.1	8	KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis"
XP_049863016.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"Attenuation phase";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation"
XP_049835444.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049859414.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049847691.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049828462.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_049836956.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049838085.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049852234.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049836328.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049831860.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049851663.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601	"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_049859078.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049836530.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049848268.1	40	KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7094;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7216;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-6883;MetaCyc: PWY-5789;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-5109;MetaCyc: PWY-7778;MetaCyc: PWY-6583;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17+1.1.1.35	"Tryptophan metabolism";"Benzoate degradation";"Limonene and pinene degradation";"Butanoate metabolism";"beta-Alanine metabolism";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Geraniol degradation";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Fatty acid salvage";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Toluene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation"
XP_049839998.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049858253.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049851810.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049840177.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049831271.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_049850085.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049828303.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049838605.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049842042.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones"
XP_049854345.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049861431.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049837219.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049827543.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049855679.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049833071.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049845246.1	4	Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807047	"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol"
XP_049857826.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049838931.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049832636.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049827896.1	8	Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation"
XP_049836986.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-190873	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Gap junction degradation"
XP_049837641.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049843096.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049850717.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049849062.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_049846246.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049837031.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049855879.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049830787.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_049843445.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049835874.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049845275.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_049829826.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049851464.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049863998.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049863714.1	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_049860993.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_049852691.1	9	KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5	"Cysteine and methionine metabolism";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism"
XP_049828589.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049859671.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049842969.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_049844146.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049850588.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5872	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_049843604.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049859005.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049851555.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049858962.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049833765.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049844354.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049848433.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_049834906.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049860942.1	18	Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-8953750;Reactome: R-HSA-5689901;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Transcriptional Regulation by E2F6";"Metalloprotease DUBs";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049835235.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049828070.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_049844147.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049832170.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049835264.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049832848.1	13	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;Reactome: R-HSA-416482;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049851529.1	8	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6"
XP_049832560.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049838718.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049854446.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049861043.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049840644.1	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-5849;MetaCyc: PWY-5890;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-7996	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I"
XP_049863778.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049830025.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049840824.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049833883.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049837486.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049834465.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_049828773.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049836957.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049845471.1	6	MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049836758.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049833020.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_049828267.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049839381.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049831005.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049861041.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049863759.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_049863768.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049860492.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049859379.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-210744	"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_049859052.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049839672.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049838393.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049864471.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049854406.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049837030.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049860193.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049852709.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049848709.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049855635.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049845242.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049859154.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049863012.1	26	Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-9614657	"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes"
XP_049858046.1	20	KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854	"beta-Alanine metabolism";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_049849509.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049842990.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049856837.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_049858698.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049837220.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049837285.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-159236;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-159230;Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-8851708;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-77595;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-72086;Reactome: R-HSA-191859;Reactome: R-HSA-167200;Reactome: R-HSA-72187	"Transport of the SLBP independent Mature mRNA";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Intronless Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Capping";"snRNP Assembly";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA 3'-end processing"
XP_049861096.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049830275.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_049844754.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049837306.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling"
XP_049852232.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049829028.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049829581.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530	"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_049832046.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049850583.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049858166.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049852060.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258	"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL"
XP_049843139.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049838159.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049838218.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049856696.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852247.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_049828248.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049840109.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_049862426.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049853138.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049847784.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72163	"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049861421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049838812.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049828646.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049855521.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049855936.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049848492.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_049860491.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049839901.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_049831107.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049831324.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_049827904.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049860536.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049834422.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049853013.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049860347.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049843558.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049858000.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049852491.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049849846.1	8	MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-191273	"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis"
XP_049857914.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049835915.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049838531.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049827776.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Processing of DNA double-strand break ends"
XP_049849736.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049835827.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049859556.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049840643.1	10	MetaCyc: PWY-5895;MetaCyc: PWY-5839;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5892	"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis"
XP_049829343.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049852320.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_049838796.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049829925.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_049864513.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049850236.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_049849786.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049863713.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_049833058.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049862836.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18	"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_049859071.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049859780.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049862237.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049837662.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049853568.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049859423.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049827901.1	11	Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400	"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER"
XP_049847887.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049856501.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_049838052.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_049846734.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_049864163.1	8	Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133	"Catecholamine biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis II"
XP_049833468.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049836855.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049857325.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049853544.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049840929.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_049864698.1	8	KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_049853140.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049855933.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049862662.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049862584.1	5	Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-110381	"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049861355.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_049829342.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049857399.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049860187.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049848676.1	18	KEGG: 00620+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-71064;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-70895	"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Glycine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism"
XP_049828510.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049842535.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142	"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049842614.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049832061.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-8963889	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes"
XP_049829473.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049851126.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049830943.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049863209.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049854250.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049855893.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049827171.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049846919.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_049858060.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049831408.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049863216.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049831868.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049861262.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049837266.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049844235.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049856233.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049847493.1	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_049842529.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049856496.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049856749.1	12	KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416	"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Plasmalogen degradation";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_049846740.1	12	MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309	"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_049831020.1	4	Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-1362409	"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049848550.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049852970.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_049855801.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Dual incision in TC-NER"
XP_049838697.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"PPARA activates gene expression"
XP_049835943.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049857902.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049844785.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049862381.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049862032.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049850130.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049848337.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049846022.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049845076.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049842545.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049831646.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133	"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1"
XP_049854561.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049848602.1	34	Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885	"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins"
XP_049859101.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-212300	"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA"
XP_049827808.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049843588.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_049861516.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_049854327.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049836405.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_049832437.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049846030.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049844113.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049830615.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049832168.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828559.1	8	MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049828174.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
XP_049859247.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049847527.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049829707.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049828400.1	20	MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726	"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Propanoate metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_049850749.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_049860789.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation"
XP_049844894.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_049835380.1	20	Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_049831696.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049840828.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049855757.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049834010.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis"
XP_049837620.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049858544.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049862742.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049846864.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049858618.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_049837091.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049854288.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702	"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling"
XP_049838570.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049847103.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049860716.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049857366.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049847271.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049826875.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049830785.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590	"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation"
XP_049836604.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467	"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_049851582.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_049828894.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049857165.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049839507.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_049829332.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049857431.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049859405.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049840426.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049860713.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049863693.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049862439.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049854799.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049837883.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049842229.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049833288.1	5	MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049854419.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049848319.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049846175.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049858816.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049832520.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049852769.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049847236.1	19	Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5913;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5172;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8	"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_049856881.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049858174.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049831990.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049842362.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049832970.1	34	Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531	"HCMV Late Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus"
XP_049837465.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049836641.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049830700.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049848059.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_049852051.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049829048.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049840642.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049857823.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049848860.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049862941.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049864182.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049850723.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757	"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Regulation of TP53 Degradation"
XP_049835879.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049863369.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049840688.1	25	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467	"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_049840631.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049849159.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049842363.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_049844135.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049843085.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049858334.1	7	Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine"
XP_049858914.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049828372.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049857161.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049851191.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049834772.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
XP_049833568.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049849840.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis"
XP_049849309.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6	"Neutrophil degranulation";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism"
XP_049860253.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848731.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-983168	"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049829881.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049858939.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049837128.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049860680.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049844442.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049833760.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049859511.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049863520.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049861637.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049839671.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049835443.1	14	Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-68877	"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase"
XP_049827114.1	4	KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis"
XP_049837757.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049849684.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049864674.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049828191.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049832857.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049858333.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-171306	"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends"
XP_049832076.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049835469.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_049858905.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049861427.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049849785.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049844969.1	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
XP_049844943.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049847995.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049829512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049859368.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049839280.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049851519.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_049835277.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049836280.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049837493.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049857659.1	7	MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336	"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway"
XP_049849865.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049860780.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692	"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion transport by P-type ATPases";"RAF activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity"
XP_049843983.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling"
XP_049845479.1	6	KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;MetaCyc: PWY-5530	"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II"
XP_049864393.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049851563.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049859524.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_049863390.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_049851044.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049863766.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049856875.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049833183.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049832180.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049829321.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049827303.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049861349.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049856503.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_049832233.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049846862.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049848104.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors"
XP_049859093.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049844331.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656	"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling"
XP_049838797.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049864152.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049845427.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_049850684.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049843088.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049851910.1	7	MetaCyc: PWY-6840;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2	"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_049858615.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049835479.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049828137.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049863218.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049829099.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049853537.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049834705.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_049863084.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049831033.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049853592.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049837146.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_049862703.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049851677.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049859596.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_049863404.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049843103.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_049827477.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_049848691.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049841052.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756	"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation"
XP_049864325.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049862394.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861723.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049844361.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049858074.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049855102.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049862577.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_049834215.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049864809.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049844542.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049835958.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049857771.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049860922.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049831398.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049863220.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049860145.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049857031.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049844556.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049839425.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049850306.1	5	Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-446388	"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_049828361.1	12	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_049838292.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049842981.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049859553.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049830348.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049834807.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049851203.1	5	KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_049836048.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049842872.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049851511.1	6	Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622	"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_049837762.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049855202.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049848236.1	5	MetaCyc: PWY-6168;KEGG: 00740+3.5.4.25;MetaCyc: PWY-7991;MetaCyc: PWY-7539;KEGG: 00790+3.5.4.25	"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Toxoflavin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)";"Folate biosynthesis"
XP_049852754.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_049848198.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism"
XP_049835965.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_049859552.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049862131.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049847294.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049853841.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049827266.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-983189	"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Aggrephagy";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Kinesins"
XP_049847997.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049827950.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049846038.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049852710.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049852021.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_049831851.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049843278.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049840740.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049833142.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049830145.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049848658.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_049853366.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049856506.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049844840.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049857563.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049863767.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049851094.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049844321.1	2	Reactome: R-HSA-8866652;Reactome: R-HSA-5357905	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TNFR1 signaling"
XP_049849575.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_049839411.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049831487.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049844425.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049830122.1	10	Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695	"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation"
XP_049859557.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049830130.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874	"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation I"
XP_049836623.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049848631.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049831169.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049837875.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)"
XP_049861640.1	7	MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;Reactome: R-HSA-5628897	"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes"
XP_049827537.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049840526.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049832917.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049860345.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049854674.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049848284.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_049839379.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049828170.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049859155.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049858098.1	10	MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)"
XP_049863095.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049833522.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049837502.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049830674.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_049844197.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049849874.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049863894.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049830830.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-5123;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7721;MetaCyc: PWY-5122	"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis"
XP_049826930.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_049860787.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049843602.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049841686.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049854289.1	13	Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-168638	"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway"
XP_049852689.1	9	KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5	"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism"
XP_049857600.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049844533.1	7	MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25	"Starch degradation V";"Glycogen degradation II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch and sucrose metabolism"
XP_049844261.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049829383.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049864764.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_049834691.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049831167.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049835865.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049856991.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049851826.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049860152.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049848469.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049851200.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049843635.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049852570.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049857774.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049859067.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049839790.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-5602498;Reactome: R-HSA-5603041;Reactome: R-HSA-5603037;Reactome: R-HSA-5602680;Reactome: R-HSA-975110;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-209543;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Interleukin-1 signaling";"ER-Phagosome pathway";"p75NTR recruits signalling complexes";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"
XP_049861197.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_049828208.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049850838.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049859004.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049848361.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049838881.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049861154.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049837500.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049852016.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_049850288.1	5	Reactome: R-HSA-416482;Reactome: R-HSA-446388;Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"Rho GTPase cycle"
XP_049843107.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049850599.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049856556.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049848468.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167200	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Neddylation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049855229.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049837386.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049832880.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676	"Neutrophil degranulation";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins"
XP_049846077.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_049831396.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049860660.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049843101.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049857828.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049836662.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049846563.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049835966.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_049843961.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049828134.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049848389.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049832521.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049843574.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049851021.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_049842089.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049851699.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_049855951.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049860740.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571	"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation"
XP_049861182.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049838279.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049833959.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy"
XP_049834339.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049844822.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_049830359.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049855230.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049861428.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827792.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049829706.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049850857.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049846587.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_049863626.1	11	Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_049857179.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049832577.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049836151.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HCMV Early Events";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_049864673.1	5	KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis"
XP_049829472.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049860107.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_049837140.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049835670.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049830741.1	9	MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7112	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification"
XP_049846946.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling"
XP_049830470.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049828418.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049836871.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049828233.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_049838235.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_049827290.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049864829.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049832075.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049854109.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757	"Dual incision in TC-NER";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation"
XP_049848145.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_049847578.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049854796.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049848247.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049829205.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049827902.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis"
XP_049864392.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049845323.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049845436.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049842333.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_049857056.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_049847586.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049846183.1	14	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_049843963.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049846633.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049850988.1	29	Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-3371453	"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response"
XP_049862344.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049842526.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049864250.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_049837993.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049858622.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049851941.1	7	MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-5659	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis"
XP_049856497.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence"
XP_049864688.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049831220.1	10	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049843071.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049836951.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049833430.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049837879.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049863691.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049853648.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049863921.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049833367.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1	"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes"
XP_049849578.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_049838795.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049850535.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049852836.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049829856.1	11	KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4	"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism"
XP_049843106.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1"
XP_049846710.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049863268.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_049857109.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049848549.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049827674.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049840829.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843153.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049847702.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_049857813.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049845435.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049848932.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-6728	"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle"
XP_049839591.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049838911.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049854149.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049853464.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049847690.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049852017.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_049831102.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049836606.1	4	Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049837051.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049837142.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049840935.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695	"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation"
XP_049844748.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049858289.1	10	MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_049859326.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049841125.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049858911.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049834269.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049860146.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049859639.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_049831853.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049839725.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834456.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049841218.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049846301.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049854361.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049833472.1	6	KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_049831700.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049860707.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300	"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF activation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling"
XP_049830883.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049855095.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_049850432.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049842309.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049830977.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049826918.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049834390.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_049847795.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049852717.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049842090.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049830873.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
XP_049831709.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism"
XP_049863594.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840	"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_049860198.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049837624.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_049834641.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_049837186.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049843347.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_049862671.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-6798695	"Digestion of dietary carbohydrate";"Neutrophil degranulation"
XP_049857954.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Mitotic Prometaphase";"snRNP Assembly";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_049848445.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049849678.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
XP_049836989.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745	"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_049845822.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049827025.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049840130.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049853264.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049859784.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049843590.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049835941.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049844333.1	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_049864705.1	8	Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_049833696.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049844562.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049851434.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049849983.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049864285.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049863228.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049836841.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049842870.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049852571.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049833043.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_049831876.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_049841761.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049831795.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049841236.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049840663.1	17	Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425	"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Propanoate metabolism";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Pyruvate metabolism";"Carnitine metabolism"
XP_049848160.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870	"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins"
XP_049833229.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049861095.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049852778.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049860106.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_049861372.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049850506.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049836284.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049828200.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049854121.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049836614.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049834784.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049836039.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049841361.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049832579.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049849537.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049835386.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049848715.1	4	KEGG: 00511+3.2.1.18;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.18;Reactome: R-HSA-1660662	"Other glycan degradation";"Sialic acid metabolism";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049828255.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049831249.1	10	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Galactose metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049860775.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049861207.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049859233.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049848238.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049832473.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049857727.1	11	Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN"
XP_049863060.1	18	MetaCyc: PWY-6642;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1	"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_049844584.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism"
XP_049846634.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049847348.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049829341.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049840745.1	14	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049848474.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437	"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand"
XP_049840732.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049836748.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049852281.1	37	Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-983170;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-204005;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-141444	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"COPII-mediated vesicle transport";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"snRNP Assembly";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049856030.1	17	Reactome: R-HSA-937072;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-1169091;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9014325	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_049831773.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838367.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049840244.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049830595.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049859804.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049842352.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049827941.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions"
XP_049829543.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049832039.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049850414.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049834425.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049833067.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049857163.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049859347.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049836351.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049827210.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049849918.1	7	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Glycogen degradation II";"Starch degradation V"
XP_049829304.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049863086.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049836156.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_049833595.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049855791.1	32	Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-167160	"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_049859623.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049856220.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_049830791.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049852450.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049840744.1	14	Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-6798695	"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neutrophil degranulation"
XP_049855215.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049862790.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049852814.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049862728.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049861117.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049845680.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_049849407.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049849446.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870	"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins"
XP_049830711.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049864482.1	7	MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049857919.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049835119.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049851144.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049856519.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049862233.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049845618.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049837136.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049862421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049834213.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049861415.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049861024.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049830421.1	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_049852039.1	8	MetaCyc: PWY-6664;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4	"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis"
XP_049847130.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946	"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants"
XP_049855309.1	7	KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500	"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle"
XP_049836644.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049864343.1	5	Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_049858254.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049831387.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049856900.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_049848935.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049840267.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049844035.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049858818.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049841521.1	5	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_049834435.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-162594	"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_049839693.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049827165.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049828561.1	8	MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049846005.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049832062.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381426	"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049847660.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049830649.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049851107.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049829459.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049837858.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049836615.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049859431.1	18	KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6643	"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"(R)-cysteate degradation";"Coenzyme M biosynthesis II"
XP_049863322.1	31	MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-6113;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-4381;Reactome: R-HSA-199220;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis"
XP_049827267.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049842938.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-5497	"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)"
XP_049830459.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049854772.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049839260.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049845079.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049838432.1	3	Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228	"Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix"
XP_049833802.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049852201.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_049853486.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049844296.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049844218.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049847880.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049864051.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049852290.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049840860.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049830203.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553	"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs"
XP_049857913.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049859460.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049846389.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049847932.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_049852292.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049845483.1	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_049830848.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049839267.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_049827775.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5689880	"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases"
XP_049834690.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049832068.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049858473.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049840216.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049858164.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049852076.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049830455.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049850617.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049848121.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049833593.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049863961.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049848931.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783	"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome"
XP_049860831.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049832843.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049827445.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497	"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049853415.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_049852126.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_049856053.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166	"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_049858252.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049859434.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049836146.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_049850450.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049852413.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049828804.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049853536.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049831178.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049861884.1	14	Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;MetaCyc: PWY-6453	"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Synthesis of PC";"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis"
XP_049852569.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049854154.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049857251.1	20	Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Human papillomavirus infection";"HSF1-dependent transactivation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription"
XP_049841745.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_049849843.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803	"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049835857.1	6	KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7395;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"N-acetyl-D-galactosamine degradation"
XP_049862515.1	2	Reactome: R-HSA-192456;Reactome: R-HSA-975634	"Digestion of dietary lipid";"Retinoid metabolism and transport"
XP_049863957.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049845200.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_049847692.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049847596.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049829917.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668	"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049860522.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049836358.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049832347.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049859480.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974	"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway"
XP_049828227.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049843499.1	12	Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-5250924;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847	"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones"
XP_049829214.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049837494.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049849739.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI"
XP_049827420.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049839352.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049828411.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049830793.1	9	MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590	"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation"
XP_049836556.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5871;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5857	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049861116.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049856488.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_049836965.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049852721.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049850245.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049828270.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049840658.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_049850008.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049838405.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-2129379;Reactome: R-HSA-1566948	"Degradation of the extracellular matrix";"Molecules associated with elastic fibres";"Elastic fibre formation"
XP_049831275.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049844150.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049847552.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049853652.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049835179.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049830969.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049852734.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049858941.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049853810.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049847550.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049853667.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049851992.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049838845.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049850665.1	40	Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749	"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs"
XP_049848086.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049832565.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049852354.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291	"HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C"
XP_049844162.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_049853887.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049851660.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049838271.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049839964.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049853720.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049850437.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-373080	"Activation of SMO";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)"
XP_049831412.1	21	MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049842539.1	15	MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7218;Reactome: R-HSA-70171	"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis"
XP_049835545.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_049853017.1	3	Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269	"Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_049863319.1	31	MetaCyc: PWY-5142;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-4381;MetaCyc: PWY-8049;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5989;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-6113;Reactome: R-HSA-163765	"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression"
XP_049850744.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858	"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity"
XP_049831161.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049846735.1	12	MetaCyc: PWY-601;MetaCyc: PWY-6936;Reactome: R-HSA-71240;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-7901;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13	"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism"
XP_049839843.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049843669.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049859832.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049849938.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049834934.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_049836032.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049830222.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049859833.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049856901.1	3	Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12	"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism"
XP_049842935.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049864758.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049864464.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049858716.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049831469.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049827017.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049850672.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_049850598.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049834827.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins"
XP_049846566.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049859690.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049837024.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049855389.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_049833777.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049831780.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049830289.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression"
XP_049854293.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702	"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling"
XP_049858302.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-195253	"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex"
XP_049829433.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049853687.1	6	Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505	"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049860494.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049847264.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049840524.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049828211.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-8951664;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049844466.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049837851.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049844307.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049852842.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049861870.1	14	Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PE";"Plasmalogen biosynthesis";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049837727.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049849755.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049835391.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001	"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade"
XP_049858044.1	20	KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854	"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_049846192.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049840059.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049847484.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049838804.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049849919.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049860168.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049846227.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly"
XP_049854574.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049839252.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049863769.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049837127.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_049851138.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049851139.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049847519.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480	"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"LDL remodeling";"VLDL clearance";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Chylomicron remodeling";"Platelet sensitization by LDL";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors"
XP_049857829.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049857786.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049831816.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049839539.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049845816.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049861143.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049864581.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049843051.1	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049828438.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049839486.1	15	Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174084	"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049862474.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049831576.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049851393.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049840626.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049841719.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1"
XP_049853431.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049862690.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049858677.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049853210.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_049848979.1	20	KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"PIP3 activates AKT signaling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049857291.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049832175.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049852985.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585	"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence"
XP_049842145.1	9	MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Pyruvate metabolism"
XP_049829557.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049837866.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049845823.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049863272.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049853243.1	1	Reactome: R-HSA-73943	"Reversal of alkylation damage by DNA dioxygenases"
XP_049860009.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049846382.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049852835.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049863960.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049829057.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049835836.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_049847957.1	11	Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856	"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_049840690.1	25	Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"Kinesins";"Recycling pathway of L1";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_049847403.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049833073.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049842414.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049830618.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049848702.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_049850579.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049830277.1	4	MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049833763.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049842140.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049828331.1	15	Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473	"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint"
XP_049861240.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049844155.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_049849472.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049854818.1	12	MetaCyc: PWY-7238;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9	"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions"
XP_049834268.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049827318.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852	"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy"
XP_049840068.1	31	Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7858;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)"
XP_049857430.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049844223.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049838257.1	10	MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13	"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism"
XP_049854339.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049828615.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049839318.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049835257.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049831564.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Mitotic Prometaphase"
XP_049857621.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049854633.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049864316.1	18	MetaCyc: PWY-7222;MetaCyc: PWY-7224;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7220	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_049856224.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_049829379.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049842814.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049840557.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772	"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling"
XP_049844496.1	10	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"RSK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection"
XP_049858898.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049863181.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049850698.1	6	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-983168;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049836682.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049840689.1	25	Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-5626467	"Kinesins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs"
XP_049860750.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571	"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation"
XP_049838034.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049846639.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049861648.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_049850168.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049861426.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049839588.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049862383.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049839211.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049838769.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049838501.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I"
XP_049857962.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049841690.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049864045.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049849508.1	58	Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-187577	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21"
XP_049829641.1	9	Reactome: R-HSA-1362277;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689	"Transcription of E2F targets under negative control by DREAM complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex"
XP_049836336.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049857955.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220	"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins"
XP_049838127.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049847238.1	19	MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-163765	"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression"
XP_049837480.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049857124.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049855339.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049835869.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049856754.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049861607.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049847324.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049843842.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049846223.1	7	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_049854657.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049848883.1	18	Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex"
XP_049850624.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049850183.1	6	MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020	"ATP biosynthesis";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import"
XP_049852868.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049834730.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049857033.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049854699.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_049838289.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049858767.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049846873.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049859705.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049852526.1	4	Reactome: R-HSA-6798695;KEGG: 00531+2.3.1.78;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291	"Neutrophil degranulation";"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C"
XP_049829880.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049840273.1	12	MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_049830500.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049832670.1	11	KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9	"Pyrimidine metabolism";"Starch and sucrose metabolism";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
XP_049833498.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049851089.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219	"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049829003.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049827002.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049835276.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049849468.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049837326.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049850217.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049847912.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049826859.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049845255.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_049844194.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049852788.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049838515.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism"
XP_049842143.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049843081.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049846166.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049861092.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock"
XP_049837287.1	7	KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism"
XP_049843092.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049864267.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049848017.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049852775.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049846060.1	9	MetaCyc: PWY-6839;MetaCyc: PWY-6322;KEGG: 00440+4.1.1.82;MetaCyc: PWY-5757;MetaCyc: PWY-8067;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6682;MetaCyc: PWY-7510;MetaCyc: PWY-7769	"2-aminoethylphosphonate biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis";"Methylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosalacine biosynthesis"
XP_049844196.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049848452.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049830207.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_049853926.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway"
XP_049838660.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_049827538.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049837527.1	11	Reactome: R-HSA-1632852;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-168138;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137	"Macroautophagy";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049839900.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_049836620.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_049831767.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049862609.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049844506.1	5	KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_049829764.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049834774.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049830684.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049861368.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049858704.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-168333	"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049839955.1	7	KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22	"Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_049857218.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049858934.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049856558.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049857286.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049837606.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864268.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049842422.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_049829274.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049832640.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049861910.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049849483.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_049849642.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049858224.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER"
XP_049828613.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049834353.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049829514.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049832080.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_049844263.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049829320.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049850692.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049828314.1	8	Reactome: R-HSA-6791461;MetaCyc: PWY-1861;KEGG: 00030+5.3.1.6;KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996	"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Rubisco shunt";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P"
XP_049839474.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049851146.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049834764.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049850161.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049846916.1	12	KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)"
XP_049835991.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049851626.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_049828525.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049855960.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_049837457.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442	"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs"
XP_049850976.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049845499.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049850386.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049850319.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049860451.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures"
XP_049835543.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049864171.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049839904.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_049844599.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049854122.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049831726.1	13	MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;Reactome: R-HSA-156590;Reactome: R-HSA-196836	"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism"
XP_049842338.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049827057.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295	"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation"
XP_049858681.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049852552.1	7	MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020	"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import"
XP_049845840.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049830139.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049862036.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049831571.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049847687.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049860393.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049855059.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049839230.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin"
XP_049863789.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_049864545.1	37	Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-204005;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9639288;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-983170;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638	"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"COPII-mediated vesicle transport";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amino acids regulate mTORC1";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"MHC class II antigen presentation";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins"
XP_049829691.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049838216.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_049838663.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049862105.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049837537.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049857156.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_049850722.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880	"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases"
XP_049863801.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049850782.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049838409.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1566948;Reactome: R-HSA-2129379	"Degradation of the extracellular matrix";"Elastic fibre formation";"Molecules associated with elastic fibres"
XP_049864296.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049848740.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049835266.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049861364.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_049853805.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049828506.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049854787.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049861836.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Synthesis of PC";"Synthesis of PE";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_049850451.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049860495.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049838383.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049861877.1	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055	"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_049852222.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049841051.1	29	Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3371511;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-68962	"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HSF1 activation";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex"
XP_049837849.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049840645.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination"
XP_049853714.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049856508.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_049836984.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_049853053.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049830708.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049860504.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049838608.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049828226.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049860501.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049837602.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049850264.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049849928.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049827948.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049840174.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049834648.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-400253	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock"
XP_049833462.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049860189.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049837135.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049859801.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049858115.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049843564.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049840603.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049829900.1	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049858456.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049828242.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049827220.1	6	MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049831722.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049840170.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049857030.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049848357.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049864265.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049849093.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049843095.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049834016.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049842415.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049851556.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049828507.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049863649.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049831193.1	10	Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695	"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation"
XP_049857091.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049839268.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049850762.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049848875.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049854869.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049842967.1	9	MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385	"Glucosylglycerol biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)"
XP_049858638.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049837489.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049855842.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049827533.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049848430.1	5	MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-196819;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Vitamin B1 (thiamin) metabolism";"mRNA Capping"
XP_049853617.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049844531.1	7	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Glycogen degradation II";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)"
XP_049860214.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049839082.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049844322.1	2	Reactome: R-HSA-8866652;Reactome: R-HSA-5357905	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TNFR1 signaling"
XP_049844874.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049848950.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049846548.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049857787.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049857912.1	5	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_049850478.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049858946.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049828147.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049849345.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049840735.1	21	Reactome: R-HSA-168638;Reactome: R-HSA-5602636;Reactome: R-HSA-5357956;Reactome: R-HSA-975144;Reactome: R-HSA-1169091;Reactome: R-HSA-168927;Reactome: R-HSA-2871837;Reactome: R-HSA-937039;Reactome: R-HSA-1810476;Reactome: R-HSA-5603029;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5603027;Reactome: R-HSA-933543;Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-5357905;Reactome: R-HSA-9020702;Reactome: R-HSA-937041;Reactome: R-HSA-5684264	"NOD1/2 Signaling Pathway";"IKBKB deficiency causes SCID";"TNFR1-induced NFkappaB signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"TICAM1, RIP1-mediated IKK complex recruitment";"FCERI mediated NF-kB activation";"IRAK1 recruits IKK complex";"RIP-mediated NFkB activation via ZBP1";"IkBA variant leads to EDA-ID";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"Regulation of TNFR1 signaling";"Interleukin-1 signaling";"IKK complex recruitment mediated by RIP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_049827448.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049840821.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_049832570.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049847688.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049830600.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_049834898.1	33	Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-69273;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6782210	"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049832531.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049833401.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049847811.1	13	MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism"
XP_049854937.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049828273.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049862871.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049833426.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049858637.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049838623.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049857092.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049847349.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049835481.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049829680.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049841468.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049834874.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049849740.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110320	"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH"
XP_049848167.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_049830878.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049845613.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049856982.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049838653.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_049827028.1	6	MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate"
XP_049857571.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049864317.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER"
XP_049850683.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049857074.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049864197.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049840246.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049829555.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049833194.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_049838165.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049838128.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049853443.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049842955.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_049861397.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049844608.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-5218921	"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Ca2+ pathway";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation"
XP_049853054.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049828992.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943	"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates"
XP_049853283.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049857267.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049831274.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049858251.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049839965.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049860586.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775	"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis"
XP_049844783.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049863043.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049833902.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049854292.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-5607764	"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling"
XP_049849099.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049830378.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049850490.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_049842930.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049836080.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049829519.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049827236.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049835955.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_049848117.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_049855675.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049853572.1	4	Reactome: R-HSA-70921;MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;MetaCyc: PWY-5030	"Histidine catabolism";"L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III"
XP_049856385.1	13	Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802952	"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human immunodeficiency virus 1 infection";"Signaling by BRAF and RAF fusions"
XP_049840172.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049850402.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049856829.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974	"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway"
XP_049843446.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049839995.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049864035.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination"
XP_049849293.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"