XM_014417656.1

Protein

Length

1,327 amino acids

Protein family membership

P-type ATPase (IPR001757)
- P-type ATPase, subfamily V (IPR006544)

Homologous superfamilies

Homologous superfamily
225 - 1,210
P-type ATPase, transmembrane domain superfamily (IPR023298)
Homologous superfamily
320 - 435
P-type ATPase, A domain superfamily (IPR008250)
542 - 757
P-type ATPase, cytoplasmic domain N (IPR023299)
Homologous superfamily
532 - 995
HAD-like superfamily (IPR036412)

1 200 400 600 800 1000 1200 1327

Domains and repeats

Domain
225 - 273
Cation-transporting P-type ATPase, N-terminal (IPR004014)

1 200 400 600 800 1000 1200 1327

Detailed signature matches

IPR023298

P-type ATPase, transmembrane domain superfamily
1. SSF81665 (Calcium A...)
  
  433 - 530
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  991 - 1,210
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
  
  225 - 319
  
  SUPERFAMILY
  SSF81665 (Calcium ATPase, transmembrane domain M)
IPR008250

P-type ATPase, A domain superfamily
1. SSF81653 (Calcium A...)
  
  320 - 435
  
  SUPERFAMILY
  SSF81653 (Calcium ATPase, transduction domain A)
IPR036412

HAD-like superfamily
1. SSF56784 (HAD-like)
  
  917 - 995
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  
  532 - 547
  
  SUPERFAMILY
  SSF56784 (HAD-like)
  
  697 - 792
  
  SUPERFAMILY
  SSF56784 (HAD-like)
IPR023299

P-type ATPase, cytoplasmic domain N
1. SSF81660 (Metal cat...)
  
  642 - 757
  
  SUPERFAMILY
  SSF81660 (Metal cation-transporting ATPase, ATP-binding domain N)
  
  542 - 614
  
  SUPERFAMILY
  SSF81660 (Metal cation-transporting ATPase, ATP-binding domain N)
2. G3DSA:3.40.11...
  
  595 - 745
  
  GENE3D
  G3DSA:3.40.1110.10 (G3DSA:3.40.1110.10)
IPR001757

P-type ATPase
1. TIGR01494
  
  450 - 562
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
  
  911 - 1,029
  
  TIGRFAMs
  TIGR01494 (TIGR01494)
IPR006544

P-type ATPase, subfamily V
1. PF12409 (P5-ATPase)
  
  64 - 202
  
  Pfam
  PF12409 (P5-ATPase)
2. TIGR01657
  
  65 - 1,191
  
  TIGRFAMs
  TIGR01657 (TIGR01657)
IPR004014

Cation-transporting P-type ATPase, N-terminal
1. PF00690 (Cation_ATP...)
  
  225 - 273
  
  Pfam
  PF00690 (Cation_ATPase_N)
IPR018303

P-type ATPase, phosphorylation site
1. PS00154 (ATPASE_E1_E2)
  
  538 - 544
  
  PROSITE patterns
  PS00154 (ATPASE_E1_E2)

no IPR

Unintegrated signatures

G3DSA:1.20.11...

435 - 549

GENE3D
G3DSA:1.20.1110.10 (G3DSA:1.20.1110.10)
G3DSA:2.70.15...

299 - 434

GENE3D
G3DSA:2.70.150.10 (G3DSA:2.70.150.10)
PF00122 (E1-E2_ATPase)

319 - 514

Pfam
PF00122 (E1-E2_ATPase)
PF00702 (Hydrolase)

673 - 791

Pfam
PF00702 (Hydrolase)

915 - 957

Pfam
PF00702 (Hydrolase)
PR00119 (CATATPASE)

944 - 963

PRINTS
PR00119 (CATATPASE)

365 - 379

PRINTS
PR00119 (CATATPASE)

536 - 550

PRINTS
PR00119 (CATATPASE)
PTHR45630 (FAMILY N...)

60 - 1,225

PANTHER
PTHR45630 (FAMILY NOT NAMED)
PTHR45630:SF8 (CATI...)

60 - 1,225

PANTHER
PTHR45630:SF8 (CATION-TRANSPORTING ATPASE 13A3-RELATED)
SFLDF00027 (p-type_...)

517 - 993

SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002 (C1.7:_P...)

517 - 993

SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
cd07542 (P-type_ATP...)

237 - 1,115

CDD
cd07542 (P-type_ATPase_cation)

Other features

mobidb-lite (disord...)

1,297 - 1,327

MobiDB Lite
mobidb-lite (disorder_prediction)
mobidb-lite (Polar)

1,297 - 1,321

MobiDB Lite
mobidb-lite (disorder_prediction)
Feature: Polar

Residue annotation

SFLDF00027

538D

nucleophile: attacks gamma phosphate moiety of ATP to form covalent intermediate, Mg2+ ligand
538D
SFLD
SFLDF00027 (p-type_atpase)
phosphorylation si...

538D

phosphorylation site
538D
CDD
cd07542 (P-type_ATPase_cation)
SFLDG00002

538D

nucleophile: attacks gamma phosphate moiety of ATP to form covalent intermediate, Mg2+ ligand
538D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
P-type ATPase sign...

538D

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)

539K

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)

540T

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)

541G

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)

542T

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)

543L

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)

544T

P-type ATPase signature motif
538D, 539K, 540T, 541G, 542T, 543L, 544T
CDD
cd07542 (P-type_ATPase_cation)
putative ATP bindi...

538D

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

539K

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

540T

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

656F

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

680K

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

681G

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

682S

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

714L

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

776T

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

777G

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

778D

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

921R

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

924P

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

927K

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

946D

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)

949N

putative ATP binding site
538D, 539K, 540T, 656F, 680K, 681G, 682S, 714L, 776T, 777G, 778D, 921R, 924P, 927K, 946D, 949N
CDD
cd07542 (P-type_ATPase_cation)
SFLDF00027

539K

probable role in phosphate transfer from ATP
539K
SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002

539K

probable role in phosphate transfer from ATP
539K
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
SFLDF00027

540T

conserved in all p-type atpases
540T, 541G, 542T
SFLD
SFLDF00027 (p-type_atpase)

541G

conserved in all p-type atpases
540T, 541G, 542T
SFLD
SFLDF00027 (p-type_atpase)

542T

conserved in all p-type atpases
540T, 541G, 542T
SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002

540T

conserved in all p-type atpases
540T, 541G, 542T
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

541G

conserved in all p-type atpases
540T, 541G, 542T
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

542T

conserved in all p-type atpases
540T, 541G, 542T
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
SFLDF00027

776T

coordinates with phosphate oxygen from ATP
776T
SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002

776T

coordinates with phosphate oxygen from ATP
776T
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
SFLDF00027

927K

stabilizes transition state of phosphoryl transfer by contacting beta & gamma phosphate oxygens of ATP
927K
SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002

927K

stabilizes transition state of phosphoryl transfer by contacting beta & gamma phosphate oxygens of ATP
927K
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
SFLDF00027

946D

Mg2+ ligand
946D, 950D
SFLD
SFLDF00027 (p-type_atpase)

950D

Mg2+ ligand
946D, 950D
SFLD
SFLDF00027 (p-type_atpase)
SFLDG00002

946D

Mg2+ ligand
946D, 950D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)

950D

Mg2+ ligand
946D, 950D
SFLD
SFLDG00002 (C1.7:_P-type_atpase_like)
putative cation bi...

1,003K

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,007A

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,008Y

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,010L

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,011M

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,027T

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,030E

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

1,031F

putative cation binding site
1,003K, 1,007A, 1,008Y, 1,010L, 1,011M, 1,027T, 1,030E, 1,031F
CDD
cd07542 (P-type_ATPase_cation)

GO term prediction

Biological Process

GO:0006812 cation transport

Molecular Function

GO:0000166 nucleotide binding
GO:0016887 ATPase activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features