Protein

XM_014418015.1

Length
1,237 amino acids

Protein family membership

Homologous superfamilies

  1. Homologous superfamily
  2. Homologous superfamily
1 200 400 600 800 1000 1237

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1237

Detailed signature matches

  1. Homologous superfamily IPR018490
    Cyclic nucleotide-binding-like
    1. SSF51206 (cAMP-bind...)
  2. Homologous superfamily IPR014710
    RmlC-like jelly roll fold
    1. G3DSA:2.60.12... (J...)
  3. Homologous superfamily IPR023578
    Ras guanine nucleotide exchange factor domain superfamily
    1. SSF48366 (Ras GEF)
  4. Homologous superfamily IPR036034
    PDZ superfamily
    1. G3DSA:2.30.42.10
    2. SSF50156 (PDZ domai...)
  5. Homologous superfamily IPR029071
    Ubiquitin-like domain superfamily
    1. SSF54236 (Ubiquitin...)
  6. Family IPR008937
    Ras-like guanine nucleotide exchange factor
    1. PTHR23113 (GUANINE ...)
  7. Domain IPR000595
    Cyclic nucleotide-binding domain
    1. cd00038 (CAP_ED)
    2. PS50042 (CNMP_BINDI...)
    3. SM00100 (cnmp_10)
  8. Domain IPR000651
    Ras-like guanine nucleotide exchange factor, N-terminal
    1. SM00229 (rasgefn_5)
    2. cd06224 (REM)
    3. PS50212 (RASGEF_NTER)
    4. PF00618 (RasGEF_N)
  9. Domain IPR001478
    PDZ domain
    1. PS50106 (PDZ)
    2. PF00595 (PDZ)
    3. SM00228 (pdz_new)
  10. Domain IPR000159
    Ras-associating (RA) domain
    1. SM00314 (RA_5)
    2. PS50200 (RA)
    3. PF00788 (RA)
  11. Domain IPR001895
    Ras guanine-nucleotide exchange factors catalytic domain
    1. cd00155 (RasGEF)
    2. PF00617 (RasGEF)
    3. SM00147 (RasGEF_3)
    4. PS50009 (RASGEF_CAT)
  12. SITE IPR019804
    Ras guanine-nucleotide exchange factor, conserved site
    1. PS00720 (RASGEF)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.87... (S...)
  2. PTHR23113:SF249 (DI...)
  3. cd00992 (PDZ_signaling)
  4. cd01785 (RA_PDZ-GEF1)

Other features

  1. mobidb-lite (disord...)
  2. mobidb-lite (Polyam...)
  3. mobidb-lite (Prolin...)
  4. mobidb-lite (Polar)

Residue annotation

  1. ligand binding sit...
  2. flexible hinge reg...
  3. GTPase interaction...
  4. protein binding si...
  5. key conserved lysi...
  6. Ras interaction si...

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding

Cellular Component

None predicted.

Generated with InterProScan 5.45-80.0