XM_014418179.1

Protein

Length

511 amino acids

Protein family membership

Alkaline phosphatase (IPR001952)

Homologous superfamilies

Homologous superfamily
19 - 497
Alkaline-phosphatase-like, core domain superfamily (IPR017850)

1 50 100 150 200 250 300 350 400 450 511

Domains and repeats

None predicted.

Detailed signature matches

IPR017850

Alkaline-phosphatase-like, core domain superfamily
1. G3DSA:3.40.72... (A...)
  
  23 - 497
  
  GENE3D
  G3DSA:3.40.720.10 (Alkaline Phosphatase)
2. SSF53649 (Alkaline ...)
  
  19 - 491
  
  SUPERFAMILY
  SSF53649 (Alkaline phosphatase-like)
IPR001952

Alkaline phosphatase
1. SM00098 (alk_phosph_2)
  
  50 - 491
  
  SMART
  SM00098 (alk_phosph_2)
2. PF00245 (Alk_phosph...)
  
  49 - 488
  
  Pfam
  PF00245 (Alk_phosphatase)
3. cd16012 (ALP)
  
  50 - 487
  
  CDD
  cd16012 (ALP)
4. PTHR11596 (ALKALINE...)
  
  23 - 497
  
  PANTHER
  PTHR11596 (ALKALINE PHOSPHATASE)
5. PR00113 (ALKPHPHTASE)
  
  148 - 168
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  207 - 217
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  49 - 69
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  300 - 329
  
  PRINTS
  PR00113 (ALKPHPHTASE)
  
  99 - 114
  
  PRINTS
  PR00113 (ALKPHPHTASE)

no IPR

Unintegrated signatures

PTHR11596:SF53 (AT0...)

23 - 497

PANTHER
PTHR11596:SF53 (AT01495P-RELATED)

Residue annotation

substrate binding ...

58D

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

101D

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

102S

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

178R

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

329D

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

333H

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

375H

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)

454H

substrate binding site
58D, 101D, 102S, 178R, 329D, 333H, 375H, 454H
CDD
cd16012 (ALP)
active site cd16012

58D

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

101D

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

102S

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

167T

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

178R

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

324E

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

329D

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

333H

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

374D

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

375H

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

454H

active site
58D, 101D, 102S, 167T, 178R, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)
metal binding site...

58D

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

102S

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

167T

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

324E

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

329D

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

333H

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

374D

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

375H

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)

454H

metal binding site
58D, 102S, 167T, 324E, 329D, 333H, 374D, 375H, 454H
CDD
cd16012 (ALP)
homodimer interfac...

62P

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

63N

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

66T

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

69R

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

70I

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

87L

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

88G

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

89A

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

91K

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

93Y

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

95A

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

99V

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

112G

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

113V

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

114K

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

124S

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

141L

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

453T

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

455G

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

456G

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

457N

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

458D

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

460F

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

470L

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

472H

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

473C

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

474I

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

475H

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

476E

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

478N

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

479Y

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

482T

homodimer interface
62P, 63N, 66T, 69R, 70I, 87L, 88G, 89A, 91K, 93Y, 95A, 99V, 112G, 113V, 114K, 124S, 141L, 453T, 455G, 456G, 457N, 458D, 460F, 470L, 472H, 473C, 474I, 475H, 476E, 478N, 479Y, 482T
CDD
cd16012 (ALP)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0016791 phosphatase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

XM_014418179.1

Protein family membership

Homologous superfamilies

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component