XM_014421715.1

Protein

Length

508 amino acids

Protein family membership

None predicted.

Homologous superfamilies

Homologous superfamily
19 - 505
Aldehyde/histidinol dehydrogenase (IPR016161)
Homologous superfamily
48 - 498
Aldehyde dehydrogenase, N-terminal (IPR016162)
Homologous superfamily
283 - 474
Aldehyde dehydrogenase, C-terminal (IPR016163)

1 50 100 150 200 250 300 350 400 450 508

Domains and repeats

Domain
39 - 502
Aldehyde dehydrogenase domain (IPR015590)

1 50 100 150 200 250 300 350 400 450 508

Detailed signature matches

IPR016161

Aldehyde/histidinol dehydrogenase
1. SSF53720 (ALDH-like)
  
  19 - 505
  
  SUPERFAMILY
  SSF53720 (ALDH-like)
IPR016162

Aldehyde dehydrogenase, N-terminal
1. G3DSA:3.40.60... (A...)
  
  475 - 498
  
  GENE3D
  G3DSA:3.40.605.10 (Aldehyde Dehydrogenase; Chain A)
  
  48 - 282
  
  GENE3D
  G3DSA:3.40.605.10 (Aldehyde Dehydrogenase; Chain A)
IPR016163

Aldehyde dehydrogenase, C-terminal
1. G3DSA:3.40.30... (A...)
  
  283 - 474
  
  GENE3D
  G3DSA:3.40.309.10 (Aldehyde Dehydrogenase; Chain A)
IPR015590

Aldehyde dehydrogenase domain
1. PF00171 (Aldedh)
  
  39 - 502
  
  Pfam
  PF00171 (Aldedh)
IPR029510

Aldehyde dehydrogenase, glutamic acid active site
1. PS00687 (ALDEHYDE_D...)
  
  277 - 284
  
  PROSITE patterns
  PS00687 (ALDEHYDE_DEHYDR_GLU)

no IPR

Unintegrated signatures

PTHR43353 (FAMILY N...)

26 - 507

PANTHER
PTHR43353 (FAMILY NOT NAMED)
PTHR43353:SF5 (SUCC...)

26 - 507

PANTHER
PTHR43353:SF5 (SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL)
cd07103 (ALDH_F5_SS...)

50 - 505

CDD
cd07103 (ALDH_F5_SSADH_GabD)

Residue annotation

tetramerization in...

88P

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

97R

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

138W

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

141E

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

142E

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

144R

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

145R

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

146I

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

147N

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

148G

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

149E

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

150I

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

151L

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

152S

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

158R

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

159E

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

160L

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

165Q

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

250G

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

262K

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

266K

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

269S

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

326D

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

330N

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

377K

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

446K

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

448I

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

449S

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

453R

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

455S

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

458I

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

460V

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

461G

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

462M

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

463V

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

464G

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

465I

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

466N

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

472T

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

475A

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

476A

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

482E

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

487R

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

499N

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

500I

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

501K

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

502Y

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

503L

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

504C

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

505F

tetramerization interface
88P, 97R, 138W, 141E, 142E, 144R, 145R, 146I, 147N, 148G, 149E, 150I, 151L, 152S, 158R, 159E, 160L, 165Q, 250G, 262K, 266K, 269S, 326D, 330N, 377K, 446K, 448I, 449S, 453R, 455S, 458I, 460V, 461G, 462M, 463V, 464G, 465I, 466N, 472T, 475A, 476A, 482E, 487R, 499N, 500I, 501K, 502Y, 503L, 504C, 505F
CDD
cd07103 (ALDH_F5_SSADH_GabD)
NAD(P) binding sit...

173I

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

174T

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

175P

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

176W

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

177N

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

185R

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

200K

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

202A

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

203E

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

254F

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

255T

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

256G

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

257S

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

260V

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

263L

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

264L

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

278E

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

279L

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

280G

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

312C

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

411E

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

413F

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

439L

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)

477F

NAD(P) binding site
173I, 174T, 175P, 176W, 177N, 185R, 200K, 202A, 203E, 254F, 255T, 256G, 257S, 260V, 263L, 264L, 278E, 279L, 280G, 312C, 411E, 413F, 439L, 477F
CDD
cd07103 (ALDH_F5_SSADH_GabD)
catalytic residues...

177N

catalytic residues
177N, 278E, 309G, 312C
CDD
cd07103 (ALDH_F5_SSADH_GabD)

278E

catalytic residues
177N, 278E, 309G, 312C
CDD
cd07103 (ALDH_F5_SSADH_GabD)

309G

catalytic residues
177N, 278E, 309G, 312C
CDD
cd07103 (ALDH_F5_SSADH_GabD)

312C

catalytic residues
177N, 278E, 309G, 312C
CDD
cd07103 (ALDH_F5_SSADH_GabD)

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Cellular Component