XM_014431886.1

Protein

Length

349 amino acids

Protein family membership

G protein-coupled receptor, rhodopsin-like (IPR000276)

Homologous superfamilies

None predicted.

Domains and repeats

Domain
56 - 320
GPCR, rhodopsin-like, 7TM (IPR017452)

1 50 100 150 200 250 300 349

Detailed signature matches

IPR000276

G protein-coupled receptor, rhodopsin-like
1. PR00237 (GPCRRHODOPSN)
  
  117 - 139
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
  
  151 - 172
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
  
  73 - 94
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
  
  200 - 223
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
  
  302 - 328
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
  
  41 - 65
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
  
  257 - 281
  
  PRINTS
  PR00237 (GPCRRHODOPSN)
IPR017452

GPCR, rhodopsin-like, 7TM
1. PF00001 (7tm_1)
  
  60 - 319
  
  Pfam
  PF00001 (7tm_1)
2. PS50262 (G_PROTEIN_...)
  
  56 - 320
  
  PROSITE profiles
  PS50262 (G_PROTEIN_RECEP_F1_2)

no IPR

Unintegrated signatures

G3DSA:1.20.10...

15 - 339

GENE3D
G3DSA:1.20.1070.10 (G3DSA:1.20.1070.10)
PTHR24229 (NEUROPEP...)

26 - 320

PANTHER
PTHR24229 (NEUROPEPTIDES RECEPTOR)
PTHR24229:SF87 (ALL...)

26 - 320

PANTHER
PTHR24229:SF87 (ALLATOSTATIN A RECEPTOR 1, ISOFORM B)
SSF81321 (Family A ...)

18 - 321

SUPERFAMILY
SSF81321 (Family A G protein-coupled receptor-like)
cd00637 (7tm_classA...)

42 - 319

CDD
cd00637 (7tm_classA_rhodopsin-like)

Residue annotation

putative ligand bi...

94V

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

97V

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

98R

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

110C

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

111R

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

112L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

113L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

114P

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

115Y

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

117Q

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

118L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

121G

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

164M

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

166L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

167F

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

168S

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

169P

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

170I

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

196S

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

199F

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

200T

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

201V

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

203V

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

204T

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

205I

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

207V

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

208C

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

272W

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

275I

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

276T

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

278V

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

279L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

282I

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

292D

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

293T

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

295F

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

302F

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

303L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

306L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

309A

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

310L

putative ligand binding pocket
94V, 97V, 98R, 110C, 111R, 112L, 113L, 114P, 115Y, 117Q, 118L, 121G, 164M, 166L, 167F, 168S, 169P, 170I, 196S, 199F, 200T, 201V, 203V, 204T, 205I, 207V, 208C, 272W, 275I, 276T, 278V, 279L, 282I, 292D, 293T, 295F, 302F, 303L, 306L, 309A, 310L
CDD
cd00637 (7tm_classA_rhodopsin-like)

GO term prediction

Biological Process

GO:0007186 G protein-coupled receptor signaling pathway

Molecular Function

GO:0004930 G protein-coupled receptor activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features