Input_protein_ID UniProt_ID Reactome_pathway_ID Reactome_pathway_name XP_046664630.1 P39205 R-DME-1430728 Metabolism XP_046664630.1 P39205 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046664630.1 P39205 R-DME-196854 Metabolism of vitamins and cofactors XP_046664630.1 P39205 R-DME-947581 Molybdenum cofactor biosynthesis XP_046673166.1 Q9W5E1 R-DME-110314 Recognition of DNA damage by PCNA-containing replication complex XP_046673166.1 Q9W5E1 R-DME-1234174 Cellular response to hypoxia XP_046673166.1 Q9W5E1 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046673166.1 Q9W5E1 R-DME-1280215 Cytokine Signaling in Immune system XP_046673166.1 Q9W5E1 R-DME-1280218 Adaptive Immune System XP_046673166.1 Q9W5E1 R-DME-162582 Signal Transduction XP_046673166.1 Q9W5E1 R-DME-1640170 Cell Cycle XP_046673166.1 Q9W5E1 R-DME-168256 Immune System XP_046673166.1 Q9W5E1 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046673166.1 Q9W5E1 R-DME-195721 Signaling by WNT XP_046673166.1 Q9W5E1 R-DME-201681 TCF dependent signaling in response to WNT XP_046673166.1 Q9W5E1 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046673166.1 Q9W5E1 R-DME-209392 Hedgehog pathway XP_046673166.1 Q9W5E1 R-DME-209412 Wingless pathway XP_046673166.1 Q9W5E1 R-DME-209441 WG ligand not bound to FZ receptors XP_046673166.1 Q9W5E1 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046673166.1 Q9W5E1 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046673166.1 Q9W5E1 R-DME-212436 Generic Transcription Pathway XP_046673166.1 Q9W5E1 R-DME-2262752 Cellular responses to stress XP_046673166.1 Q9W5E1 R-DME-388841 Regulation of T cell activation by CD28 family XP_046673166.1 Q9W5E1 R-DME-389948 Co-inhibition by PD-1 XP_046673166.1 Q9W5E1 R-DME-392499 Metabolism of proteins XP_046673166.1 Q9W5E1 R-DME-446652 Interleukin-1 family signaling XP_046673166.1 Q9W5E1 R-DME-449147 Signaling by Interleukins XP_046673166.1 Q9W5E1 R-DME-453274 Mitotic G2-G2/M phases XP_046673166.1 Q9W5E1 R-DME-4641258 Degradation of DVL XP_046673166.1 Q9W5E1 R-DME-5252538 Drosophila signaling pathways XP_046673166.1 Q9W5E1 R-DME-5358351 Signaling by Hedgehog XP_046673166.1 Q9W5E1 R-DME-5610780 Degradation of GLI1 by the proteasome XP_046673166.1 Q9W5E1 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046673166.1 Q9W5E1 R-DME-5610787 Hedgehog 'off' state XP_046673166.1 Q9W5E1 R-DME-5632684 Hedgehog 'on' state XP_046673166.1 Q9W5E1 R-DME-5696394 DNA Damage Recognition in GG-NER XP_046673166.1 Q9W5E1 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046673166.1 Q9W5E1 R-DME-5696398 Nucleotide Excision Repair XP_046673166.1 Q9W5E1 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046673166.1 Q9W5E1 R-DME-5696400 Dual Incision in GG-NER XP_046673166.1 Q9W5E1 R-DME-597592 Post-translational protein modification XP_046673166.1 Q9W5E1 R-DME-6781823 Formation of TC-NER Pre-Incision Complex XP_046673166.1 Q9W5E1 R-DME-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) XP_046673166.1 Q9W5E1 R-DME-6782135 Dual incision in TC-NER XP_046673166.1 Q9W5E1 R-DME-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER XP_046673166.1 Q9W5E1 R-DME-68949 Orc1 removal from chromatin XP_046673166.1 Q9W5E1 R-DME-69052 Switching of origins to a post-replicative state XP_046673166.1 Q9W5E1 R-DME-69239 Synthesis of DNA XP_046673166.1 Q9W5E1 R-DME-69242 S Phase XP_046673166.1 Q9W5E1 R-DME-69275 G2/M Transition XP_046673166.1 Q9W5E1 R-DME-69278 Cell Cycle, Mitotic XP_046673166.1 Q9W5E1 R-DME-69306 DNA Replication XP_046673166.1 Q9W5E1 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046673166.1 Q9W5E1 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046673166.1 Q9W5E1 R-DME-69615 G1/S DNA Damage Checkpoints XP_046673166.1 Q9W5E1 R-DME-69620 Cell Cycle Checkpoints XP_046673166.1 Q9W5E1 R-DME-72766 Translation XP_046673166.1 Q9W5E1 R-DME-73857 RNA Polymerase II Transcription XP_046673166.1 Q9W5E1 R-DME-73893 DNA Damage Bypass XP_046673166.1 Q9W5E1 R-DME-73894 DNA Repair XP_046673166.1 Q9W5E1 R-DME-74160 Gene expression (Transcription) XP_046673166.1 Q9W5E1 R-DME-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis XP_046673166.1 Q9W5E1 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046673166.1 Q9W5E1 R-DME-8939902 Regulation of RUNX2 expression and activity XP_046673166.1 Q9W5E1 R-DME-8951664 Neddylation XP_046673166.1 Q9W5E1 R-DME-8953897 Cellular responses to stimuli XP_046673166.1 Q9W5E1 R-DME-9020702 Interleukin-1 signaling XP_046673166.1 Q9W5E1 R-DME-9711123 Cellular response to chemical stress XP_046673166.1 Q9W5E1 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046673166.1 Q9W5E1 R-DME-9759194 Nuclear events mediated by NFE2L2 XP_046673166.1 Q9W5E1 R-DME-9762114 GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 XP_046673166.1 Q9W5E1 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046673166.1 Q9W5E1 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046673166.1 Q9W5E1 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046673166.1 Q9W5E1 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046673166.1 Q9W5E1 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046673166.1 Q9W5E1 R-DME-9948299 Ribosome-associated quality control XP_046673166.1 Q9W5E1 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046677614.1 Q9W589 R-DME-392499 Metabolism of proteins XP_046677614.1 Q9W589 R-DME-5173105 O-linked glycosylation XP_046677614.1 Q9W589 R-DME-5173214 O-glycosylation of TSR domain-containing proteins XP_046677614.1 Q9W589 R-DME-597592 Post-translational protein modification XP_046668268.1 P29349 R-DME-168249 Innate Immune System XP_046668268.1 P29349 R-DME-168256 Immune System XP_046668268.1 P29349 R-DME-6798695 Neutrophil degranulation XP_046668265.1 P41572 R-DME-1430728 Metabolism XP_046668265.1 P41572 R-DME-71336 Pentose phosphate pathway XP_046668265.1 P41572 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682782.1 O97418 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682782.1 O97418 R-DME-1430728 Metabolism XP_046682782.1 O97418 R-DME-611105 Respiratory electron transport XP_046682782.1 O97418 R-DME-6799198 Complex I biogenesis XP_046669698.1 P11346 R-DME-109582 Hemostasis XP_046669698.1 P11346 R-DME-1280218 Adaptive Immune System XP_046669698.1 P11346 R-DME-1295596 Spry regulation of FGF signaling XP_046669698.1 P11346 R-DME-162582 Signal Transduction XP_046669698.1 P11346 R-DME-166520 Signaling by NTRKs XP_046669698.1 P11346 R-DME-168249 Innate Immune System XP_046669698.1 P11346 R-DME-168256 Immune System XP_046669698.1 P11346 R-DME-169893 Prolonged ERK activation events XP_046669698.1 P11346 R-DME-170968 Frs2-mediated activation XP_046669698.1 P11346 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046669698.1 P11346 R-DME-187687 Signalling to ERKs XP_046669698.1 P11346 R-DME-190236 Signaling by FGFR XP_046669698.1 P11346 R-DME-209159 Assembly of the CI containing complexes XP_046669698.1 P11346 R-DME-209190 Phosphorylation of CI XP_046669698.1 P11346 R-DME-209214 Phosphorylation of SMO XP_046669698.1 P11346 R-DME-209392 Hedgehog pathway XP_046669698.1 P11346 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046669698.1 P11346 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046669698.1 P11346 R-DME-216217 Activation of SMO XP_046669698.1 P11346 R-DME-392517 Rap1 signalling XP_046669698.1 P11346 R-DME-430116 GP1b-IX-V activation signalling XP_046669698.1 P11346 R-DME-432553 Phosphorylation of PER and TIM XP_046669698.1 P11346 R-DME-432626 Circadian Clock pathway XP_046669698.1 P11346 R-DME-5252538 Drosophila signaling pathways XP_046669698.1 P11346 R-DME-5621481 C-type lectin receptors (CLRs) XP_046669698.1 P11346 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046669698.1 P11346 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046669698.1 P11346 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046669698.1 P11346 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046669698.1 P11346 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046669698.1 P11346 R-DME-5654736 Signaling by FGFR1 XP_046669698.1 P11346 R-DME-5654738 Signaling by FGFR2 XP_046669698.1 P11346 R-DME-5654741 Signaling by FGFR3 XP_046669698.1 P11346 R-DME-5654743 Signaling by FGFR4 XP_046669698.1 P11346 R-DME-5673000 RAF activation XP_046669698.1 P11346 R-DME-5673001 RAF/MAP kinase cascade XP_046669698.1 P11346 R-DME-5674135 MAP2K and MAPK activation XP_046669698.1 P11346 R-DME-5674499 Negative feedback regulation of MAPK pathway XP_046669698.1 P11346 R-DME-5675221 Negative regulation of MAPK pathway XP_046669698.1 P11346 R-DME-5683057 MAPK family signaling cascades XP_046669698.1 P11346 R-DME-5684996 MAPK1/MAPK3 signaling XP_046669698.1 P11346 R-DME-76002 Platelet activation, signaling and aggregation XP_046669698.1 P11346 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046680182.1 O46098 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046680182.1 O46098 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046680182.1 O46098 R-DME-1430728 Metabolism XP_046680182.1 O46098 R-DME-611105 Respiratory electron transport XP_046680182.1 O46098 R-DME-9865881 Complex III assembly XP_046687896.1 Q9W4X6 R-DME-168249 Innate Immune System XP_046687896.1 Q9W4X6 R-DME-168256 Immune System XP_046687896.1 Q9W4X6 R-DME-6798695 Neutrophil degranulation XP_046665479.1 Q9W4Y6 R-DME-209338 Assembly of the 'signalling complexes' XP_046665479.1 Q9W4Y6 R-DME-209392 Hedgehog pathway XP_046665479.1 Q9W4Y6 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046665479.1 Q9W4Y6 R-DME-5252538 Drosophila signaling pathways XP_046665479.1 A8JUV7 R-DME-1266738 Developmental Biology XP_046665479.1 A8JUV7 R-DME-168249 Innate Immune System XP_046665479.1 A8JUV7 R-DME-168256 Immune System XP_046665479.1 A8JUV7 R-DME-373760 L1CAM interactions XP_046665479.1 A8JUV7 R-DME-422475 Axon guidance XP_046665479.1 A8JUV7 R-DME-447043 Neurofascin interactions XP_046665479.1 A8JUV7 R-DME-6798695 Neutrophil degranulation XP_046665479.1 A8JUV7 R-DME-9675108 Nervous system development XP_046663863.1 P18431 R-DME-1266738 Developmental Biology XP_046663863.1 P18431 R-DME-162582 Signal Transduction XP_046663863.1 P18431 R-DME-1640170 Cell Cycle XP_046663863.1 P18431 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046663863.1 P18431 R-DME-195721 Signaling by WNT XP_046663863.1 P18431 R-DME-196299 Beta-catenin phosphorylation cascade XP_046663863.1 P18431 R-DME-201681 TCF dependent signaling in response to WNT XP_046663863.1 P18431 R-DME-209155 Phosphorylation of AXN and APC XP_046663863.1 P18431 R-DME-209159 Assembly of the CI containing complexes XP_046663863.1 P18431 R-DME-209190 Phosphorylation of CI XP_046663863.1 P18431 R-DME-209214 Phosphorylation of SMO XP_046663863.1 P18431 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046663863.1 P18431 R-DME-209387 Phosphorylation of ARR XP_046663863.1 P18431 R-DME-209392 Hedgehog pathway XP_046663863.1 P18431 R-DME-209396 Phosphorylation of ARM XP_046663863.1 P18431 R-DME-209412 Wingless pathway XP_046663863.1 P18431 R-DME-209413 Assembly of the 'destruction complex' XP_046663863.1 P18431 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046663863.1 P18431 R-DME-209441 WG ligand not bound to FZ receptors XP_046663863.1 P18431 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046663863.1 P18431 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046663863.1 P18431 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046663863.1 P18431 R-DME-209469 WG ligand bound to FZ receptors XP_046663863.1 P18431 R-DME-209472 Assembly of receptor complex XP_046663863.1 P18431 R-DME-216217 Activation of SMO XP_046663863.1 P18431 R-DME-2262752 Cellular responses to stress XP_046663863.1 P18431 R-DME-3371453 Regulation of HSF1-mediated heat shock response XP_046663863.1 P18431 R-DME-3371556 Cellular response to heat stress XP_046663863.1 P18431 R-DME-432553 Phosphorylation of PER and TIM XP_046663863.1 P18431 R-DME-432626 Circadian Clock pathway XP_046663863.1 P18431 R-DME-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane XP_046663863.1 P18431 R-DME-5252538 Drosophila signaling pathways XP_046663863.1 P18431 R-DME-5358351 Signaling by Hedgehog XP_046663863.1 P18431 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046663863.1 P18431 R-DME-5610787 Hedgehog 'off' state XP_046663863.1 P18431 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046663863.1 P18431 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046663863.1 P18431 R-DME-69615 G1/S DNA Damage Checkpoints XP_046663863.1 P18431 R-DME-69620 Cell Cycle Checkpoints XP_046663863.1 P18431 R-DME-8953897 Cellular responses to stimuli XP_046663863.1 P18431 R-DME-9711123 Cellular response to chemical stress XP_046663863.1 P18431 R-DME-9730414 MITF-M-regulated melanocyte development XP_046663863.1 P18431 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046663863.1 P18431 R-DME-9759194 Nuclear events mediated by NFE2L2 XP_046663863.1 P18431 R-DME-9762114 GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 XP_046663863.1 P18431 R-DME-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity XP_046678443.1 Q9W4N8 R-DME-1430728 Metabolism XP_046678443.1 Q9W4N8 R-DME-1660661 Sphingolipid de novo biosynthesis XP_046678443.1 Q9W4N8 R-DME-168249 Innate Immune System XP_046678443.1 Q9W4N8 R-DME-168256 Immune System XP_046678443.1 Q9W4N8 R-DME-428157 Sphingolipid metabolism XP_046678443.1 Q9W4N8 R-DME-556833 Metabolism of lipids XP_046678443.1 Q9W4N8 R-DME-6798695 Neutrophil degranulation XP_046678443.1 Q9W4N8 R-DME-9609507 Protein localization XP_046678443.1 Q9W4N8 R-DME-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane XP_046687219.1 O97422 R-DME-1430728 Metabolism XP_046687219.1 O97422 R-DME-1630316 Glycosaminoglycan metabolism XP_046687219.1 O97422 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046687219.1 O97422 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046665174.1 Q9W4K8 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046665174.1 Q9W4K8 R-DME-1430728 Metabolism XP_046665174.1 Q9W4K8 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046665174.1 Q9W4K8 R-DME-70268 Pyruvate metabolism XP_046665174.1 Q9W4K8 R-DME-9861718 Regulation of pyruvate metabolism XP_046665476.1 P34082 R-DME-109582 Hemostasis XP_046665476.1 P34082 R-DME-1266738 Developmental Biology XP_046665476.1 P34082 R-DME-1474228 Degradation of the extracellular matrix XP_046665476.1 P34082 R-DME-1474244 Extracellular matrix organization XP_046665476.1 P34082 R-DME-202733 Cell surface interactions at the vascular wall XP_046665476.1 P34082 R-DME-210991 Basigin interactions XP_046665476.1 P34082 R-DME-216083 Integrin cell surface interactions XP_046665476.1 P34082 R-DME-376176 Signaling by ROBO receptors XP_046665476.1 P34082 R-DME-382551 Transport of small molecules XP_046665476.1 P34082 R-DME-422475 Axon guidance XP_046665476.1 P34082 R-DME-425407 SLC-mediated transmembrane transport XP_046665476.1 P34082 R-DME-428542 Regulation of commissural axon pathfinding by SLIT and ROBO XP_046665476.1 P34082 R-DME-433692 Proton-coupled monocarboxylate transport XP_046665476.1 P34082 R-DME-9675108 Nervous system development XP_046665476.1 P34082 R-DME-9748784 Drug ADME XP_046665476.1 P34082 R-DME-9749641 Aspirin ADME XP_046665476.1 P34082 R-DME-9955298 SLC-mediated transport of organic anions XP_046667979.1 Q7KVX1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046667979.1 Q7KVX1 R-DME-1430728 Metabolism XP_046667979.1 Q7KVX1 R-DME-162582 Signal Transduction XP_046667979.1 Q7KVX1 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046667979.1 Q7KVX1 R-DME-392499 Metabolism of proteins XP_046667979.1 Q7KVX1 R-DME-5362517 Signaling by Retinoic Acid XP_046667979.1 Q7KVX1 R-DME-70268 Pyruvate metabolism XP_046667979.1 Q7KVX1 R-DME-9006931 Signaling by Nuclear Receptors XP_046667979.1 Q7KVX1 R-DME-9837999 Mitochondrial protein degradation XP_046667979.1 Q7KVX1 R-DME-9861559 PDH complex synthesizes acetyl-CoA from PYR XP_046667979.1 Q7KVX1 R-DME-9861718 Regulation of pyruvate metabolism XP_046667785.1 Q9W4F7 R-DME-1430728 Metabolism XP_046667785.1 Q9W4F7 R-DME-1630316 Glycosaminoglycan metabolism XP_046667785.1 Q9W4F7 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046667785.1 Q9W4F7 R-DME-168249 Innate Immune System XP_046667785.1 Q9W4F7 R-DME-168256 Immune System XP_046667785.1 Q9W4F7 R-DME-2024096 HS-GAG degradation XP_046667785.1 Q9W4F7 R-DME-6798695 Neutrophil degranulation XP_046667785.1 Q9W4F7 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046673294.1 Q9W4F5 R-DME-168249 Innate Immune System XP_046673294.1 Q9W4F5 R-DME-168256 Immune System XP_046673294.1 Q9W4F5 R-DME-6798695 Neutrophil degranulation XP_046684323.1 Q9W4A9 R-DME-162582 Signal Transduction XP_046684323.1 Q9W4A9 R-DME-194315 Signaling by Rho GTPases XP_046684323.1 Q9W4A9 R-DME-9012999 RHO GTPase cycle XP_046684323.1 Q9W4A9 R-DME-9013148 CDC42 GTPase cycle XP_046684323.1 Q9W4A9 R-DME-9013149 RAC1 GTPase cycle XP_046684323.1 Q9W4A9 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046677697.1 Q9W493 R-DME-392499 Metabolism of proteins XP_046677697.1 Q9W493 R-DME-5173105 O-linked glycosylation XP_046677697.1 Q9W493 R-DME-5173214 O-glycosylation of TSR domain-containing proteins XP_046677697.1 Q9W493 R-DME-597592 Post-translational protein modification XP_046658511.1 Q9W481 R-DME-392499 Metabolism of proteins XP_046658511.1 Q9W481 R-DME-4085001 Sialic acid metabolism XP_046658511.1 Q9W481 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046658511.1 Q9W481 R-DME-446203 Asparagine N-linked glycosylation XP_046658511.1 Q9W481 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046658511.1 Q9W481 R-DME-597592 Post-translational protein modification XP_046662629.1 Q9W429 R-DME-382551 Transport of small molecules XP_046662629.1 Q9W429 R-DME-425397 Transport of vitamins, nucleosides, and related molecules XP_046662629.1 Q9W429 R-DME-425407 SLC-mediated transmembrane transport XP_046662629.1 Q9W429 R-DME-727802 Transport of nucleotide sugars XP_046671171.1 P40423 R-DME-1266738 Developmental Biology XP_046671171.1 P40423 R-DME-2682334 EPH-Ephrin signaling XP_046671171.1 P40423 R-DME-350416 Regulation of non-muscle Myosin II XP_046671171.1 P40423 R-DME-350431 Planar Cell Polarity pathway XP_046671171.1 P40423 R-DME-350480 Activation of non-muscle Myosin II XP_046671171.1 P40423 R-DME-3928664 Ephrin signaling XP_046671171.1 P40423 R-DME-397014 Muscle contraction XP_046671171.1 P40423 R-DME-422475 Axon guidance XP_046671171.1 P40423 R-DME-445355 Smooth Muscle Contraction XP_046671171.1 P40423 R-DME-450736 Activation of Downstream Effectors XP_046671171.1 P40423 R-DME-450799 RHO1 signalling XP_046671171.1 P40423 R-DME-5252538 Drosophila signaling pathways XP_046671171.1 P40423 R-DME-9675108 Nervous system development XP_046663296.1 Q9W437 R-DME-1257604 PIP3 activates AKT signaling XP_046663296.1 Q9W437 R-DME-162582 Signal Transduction XP_046663296.1 Q9W437 R-DME-1632852 Macroautophagy XP_046663296.1 Q9W437 R-DME-165159 MTOR signalling XP_046663296.1 Q9W437 R-DME-166208 mTORC1-mediated signalling XP_046663296.1 Q9W437 R-DME-212436 Generic Transcription Pathway XP_046663296.1 Q9W437 R-DME-2262752 Cellular responses to stress XP_046663296.1 Q9W437 R-DME-3371556 Cellular response to heat stress XP_046663296.1 Q9W437 R-DME-3371571 HSF1-dependent transactivation XP_046663296.1 Q9W437 R-DME-3700989 Transcriptional Regulation by TP53 XP_046663296.1 Q9W437 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046663296.1 Q9W437 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046663296.1 Q9W437 R-DME-6807070 PTEN Regulation XP_046663296.1 Q9W437 R-DME-73857 RNA Polymerase II Transcription XP_046663296.1 Q9W437 R-DME-74160 Gene expression (Transcription) XP_046663296.1 Q9W437 R-DME-8943724 Regulation of PTEN gene transcription XP_046663296.1 Q9W437 R-DME-8953897 Cellular responses to stimuli XP_046663296.1 Q9W437 R-DME-9006925 Intracellular signaling by second messengers XP_046663296.1 Q9W437 R-DME-9612973 Autophagy XP_046663296.1 Q9W437 R-DME-9639288 Amino acids regulate mTORC1 XP_046663296.1 Q9W437 R-DME-9711097 Cellular response to starvation XP_046680678.1 Q23985 R-DME-157118 Signaling by NOTCH XP_046680678.1 Q23985 R-DME-162582 Signal Transduction XP_046680678.1 Q23985 R-DME-1980143 Signaling by NOTCH1 XP_046680678.1 Q23985 R-DME-2122948 Activated NOTCH1 Transmits Signal to the Nucleus XP_046677617.1 Q9W402 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046677617.1 Q9W402 R-DME-1430728 Metabolism XP_046677617.1 Q9W402 R-DME-392499 Metabolism of proteins XP_046677617.1 Q9W402 R-DME-611105 Respiratory electron transport XP_046677617.1 Q9W402 R-DME-6799198 Complex I biogenesis XP_046677617.1 Q9W402 R-DME-9837999 Mitochondrial protein degradation XP_046661069.1 Q9W3W4 R-DME-1430728 Metabolism XP_046661069.1 Q9W3W4 R-DME-196854 Metabolism of vitamins and cofactors XP_046661069.1 Q9W3W4 R-DME-2142789 Ubiquinol biosynthesis XP_046661069.1 Q9W3W4 R-DME-8978934 Metabolism of cofactors XP_046665129.1 Q9W3V8 R-DME-392499 Metabolism of proteins XP_046665129.1 Q9W3V8 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046665129.1 Q9W3V8 R-DME-446203 Asparagine N-linked glycosylation XP_046665129.1 Q9W3V8 R-DME-597592 Post-translational protein modification XP_046672884.1 Q9W3V1 R-DME-168249 Innate Immune System XP_046672884.1 Q9W3V1 R-DME-168256 Immune System XP_046672884.1 Q9W3V1 R-DME-189085 Digestion of dietary carbohydrate XP_046672884.1 Q9W3V1 R-DME-6798695 Neutrophil degranulation XP_046672884.1 Q9W3V1 R-DME-8935690 Digestion XP_046672884.1 Q9W3V1 R-DME-8963743 Digestion and absorption XP_046669028.1 Q9W3Q1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046669028.1 Q9W3Q1 R-DME-1430728 Metabolism XP_046669028.1 Q9W3Q1 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046669028.1 Q9W3Q1 R-DME-70268 Pyruvate metabolism XP_046669028.1 Q9W3Q1 R-DME-9861718 Regulation of pyruvate metabolism XP_046673998.1 Q9W3N6 R-DME-199977 ER to Golgi Anterograde Transport XP_046673998.1 Q9W3N6 R-DME-199991 Membrane Trafficking XP_046673998.1 Q9W3N6 R-DME-204005 COPII-mediated vesicle transport XP_046673998.1 Q9W3N6 R-DME-392499 Metabolism of proteins XP_046673998.1 Q9W3N6 R-DME-446203 Asparagine N-linked glycosylation XP_046673998.1 Q9W3N6 R-DME-5653656 Vesicle-mediated transport XP_046673998.1 Q9W3N6 R-DME-597592 Post-translational protein modification XP_046673998.1 Q9W3N6 R-DME-6807878 COPI-mediated anterograde transport XP_046673998.1 Q9W3N6 R-DME-948021 Transport to the Golgi and subsequent modification XP_046668937.1 Q9W3N8 R-DME-1640170 Cell Cycle XP_046668937.1 Q9W3N8 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046668937.1 Q9W3N8 R-DME-176409 APC/C:Cdc20 mediated degradation of mitotic proteins XP_046668937.1 Q9W3N8 R-DME-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins XP_046668937.1 Q9W3N8 R-DME-179409 APC-Cdc20 mediated degradation of Nek2A XP_046668937.1 Q9W3N8 R-DME-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint XP_046668937.1 Q9W3N8 R-DME-453276 Regulation of mitotic cell cycle XP_046668937.1 Q9W3N8 R-DME-69278 Cell Cycle, Mitotic XP_046684021.1 O96660 R-DME-1181150 Signaling by NODAL XP_046684021.1 O96660 R-DME-1266738 Developmental Biology XP_046684021.1 O96660 R-DME-1502540 Signaling by Activin XP_046684021.1 O96660 R-DME-162582 Signal Transduction XP_046684021.1 O96660 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046684021.1 O96660 R-DME-212436 Generic Transcription Pathway XP_046684021.1 O96660 R-DME-2173788 Downregulation of TGF-beta receptor signaling XP_046684021.1 O96660 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046684021.1 O96660 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046684021.1 O96660 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046684021.1 O96660 R-DME-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription XP_046684021.1 O96660 R-DME-392499 Metabolism of proteins XP_046684021.1 O96660 R-DME-5688426 Deubiquitination XP_046684021.1 O96660 R-DME-5689880 Ub-specific processing proteases XP_046684021.1 O96660 R-DME-597592 Post-translational protein modification XP_046684021.1 O96660 R-DME-73857 RNA Polymerase II Transcription XP_046684021.1 O96660 R-DME-74160 Gene expression (Transcription) XP_046684021.1 O96660 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046684021.1 O96660 R-DME-8941855 RUNX3 regulates CDKN1A transcription XP_046684021.1 O96660 R-DME-9006936 Signaling by TGFB family members XP_046684021.1 O96660 R-DME-9614085 FOXO-mediated transcription XP_046684021.1 O96660 R-DME-9617828 FOXO-mediated transcription of cell cycle genes XP_046667595.1 Q9W3B3 R-DME-1430728 Metabolism XP_046667595.1 Q9W3B3 R-DME-189445 Metabolism of porphyrins XP_046667595.1 Q9W3B3 R-DME-189451 Heme biosynthesis XP_046678094.1 Q24324 R-DME-110056 MAPK3 (ERK1) activation XP_046678094.1 Q24324 R-DME-112409 RAF-independent MAPK1/3 activation XP_046678094.1 Q24324 R-DME-112411 MAPK1 (ERK2) activation XP_046678094.1 Q24324 R-DME-1266738 Developmental Biology XP_046678094.1 Q24324 R-DME-162582 Signal Transduction XP_046678094.1 Q24324 R-DME-166520 Signaling by NTRKs XP_046678094.1 Q24324 R-DME-169893 Prolonged ERK activation events XP_046678094.1 Q24324 R-DME-170968 Frs2-mediated activation XP_046678094.1 Q24324 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046678094.1 Q24324 R-DME-187687 Signalling to ERKs XP_046678094.1 Q24324 R-DME-209159 Assembly of the CI containing complexes XP_046678094.1 Q24324 R-DME-209190 Phosphorylation of CI XP_046678094.1 Q24324 R-DME-209214 Phosphorylation of SMO XP_046678094.1 Q24324 R-DME-209392 Hedgehog pathway XP_046678094.1 Q24324 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046678094.1 Q24324 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046678094.1 Q24324 R-DME-216217 Activation of SMO XP_046678094.1 Q24324 R-DME-373760 L1CAM interactions XP_046678094.1 Q24324 R-DME-422475 Axon guidance XP_046678094.1 Q24324 R-DME-432553 Phosphorylation of PER and TIM XP_046678094.1 Q24324 R-DME-432626 Circadian Clock pathway XP_046678094.1 Q24324 R-DME-445144 Signal transduction by L1 XP_046678094.1 Q24324 R-DME-5252538 Drosophila signaling pathways XP_046678094.1 Q24324 R-DME-5673000 RAF activation XP_046678094.1 Q24324 R-DME-5673001 RAF/MAP kinase cascade XP_046678094.1 Q24324 R-DME-5674135 MAP2K and MAPK activation XP_046678094.1 Q24324 R-DME-5674499 Negative feedback regulation of MAPK pathway XP_046678094.1 Q24324 R-DME-5675221 Negative regulation of MAPK pathway XP_046678094.1 Q24324 R-DME-5683057 MAPK family signaling cascades XP_046678094.1 Q24324 R-DME-5684996 MAPK1/MAPK3 signaling XP_046678094.1 Q24324 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046678094.1 Q24324 R-DME-9675108 Nervous system development XP_046678272.1 Q24319 R-DME-168249 Innate Immune System XP_046678272.1 Q24319 R-DME-168256 Immune System XP_046678272.1 Q24319 R-DME-6798695 Neutrophil degranulation XP_046685088.1 Q9W330 R-DME-1430728 Metabolism XP_046685088.1 Q9W330 R-DME-168249 Innate Immune System XP_046685088.1 Q9W330 R-DME-168256 Immune System XP_046685088.1 Q9W330 R-DME-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein XP_046685088.1 Q9W330 R-DME-392499 Metabolism of proteins XP_046685088.1 Q9W330 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046685088.1 Q9W330 R-DME-446203 Asparagine N-linked glycosylation XP_046685088.1 Q9W330 R-DME-446205 Synthesis of GDP-mannose XP_046685088.1 Q9W330 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046685088.1 Q9W330 R-DME-597592 Post-translational protein modification XP_046685088.1 Q9W330 R-DME-6798695 Neutrophil degranulation XP_046685088.1 Q9W330 R-DME-70171 Glycolysis XP_046685088.1 Q9W330 R-DME-70326 Glucose metabolism XP_046685088.1 Q9W330 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046665680.1 Q9W2X6 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046665680.1 Q9W2X6 R-DME-1430728 Metabolism XP_046665680.1 Q9W2X6 R-DME-1592230 Mitochondrial biogenesis XP_046665680.1 Q9W2X6 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046665680.1 Q9W2X6 R-DME-1852241 Organelle biogenesis and maintenance XP_046665680.1 Q9W2X6 R-DME-8949613 Cristae formation XP_046662497.1 Q7JYH3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046662497.1 Q7JYH3 R-DME-1430728 Metabolism XP_046662497.1 Q7JYH3 R-DME-611105 Respiratory electron transport XP_046662497.1 Q7JYH3 R-DME-6799198 Complex I biogenesis XP_046666181.1 Q8MLW5 R-DME-1430728 Metabolism XP_046666181.1 Q8MLW5 R-DME-70263 Gluconeogenesis XP_046666181.1 Q8MLW5 R-DME-70326 Glucose metabolism XP_046666181.1 Q8MLW5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046671163.1 P04412 R-DME-1227986 Signaling by ERBB2 XP_046671163.1 P04412 R-DME-1236394 Signaling by ERBB4 XP_046671163.1 P04412 R-DME-1250196 SHC1 events in ERBB2 signaling XP_046671163.1 P04412 R-DME-1250342 PI3K events in ERBB4 signaling XP_046671163.1 P04412 R-DME-1250347 SHC1 events in ERBB4 signaling XP_046671163.1 P04412 R-DME-1251985 Nuclear signaling by ERBB4 XP_046671163.1 P04412 R-DME-1253288 Downregulation of ERBB4 signaling XP_046671163.1 P04412 R-DME-1257604 PIP3 activates AKT signaling XP_046671163.1 P04412 R-DME-1266738 Developmental Biology XP_046671163.1 P04412 R-DME-1358803 Downregulation of ERBB2:ERBB3 signaling XP_046671163.1 P04412 R-DME-162582 Signal Transduction XP_046671163.1 P04412 R-DME-177929 Signaling by EGFR XP_046671163.1 P04412 R-DME-179812 GRB2 events in EGFR signaling XP_046671163.1 P04412 R-DME-180292 GAB1 signalosome XP_046671163.1 P04412 R-DME-180336 SHC1 events in EGFR signaling XP_046671163.1 P04412 R-DME-182971 EGFR downregulation XP_046671163.1 P04412 R-DME-1963640 GRB2 events in ERBB2 signaling XP_046671163.1 P04412 R-DME-1963642 PI3K events in ERBB2 signaling XP_046671163.1 P04412 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046671163.1 P04412 R-DME-199991 Membrane Trafficking XP_046671163.1 P04412 R-DME-212718 EGFR interacts with phospholipase C-gamma XP_046671163.1 P04412 R-DME-2179392 EGFR Transactivation by Gastrin XP_046671163.1 P04412 R-DME-372790 Signaling by GPCR XP_046671163.1 P04412 R-DME-373755 Semaphorin interactions XP_046671163.1 P04412 R-DME-373760 L1CAM interactions XP_046671163.1 P04412 R-DME-388396 GPCR downstream signalling XP_046671163.1 P04412 R-DME-400685 Sema4D in semaphorin signaling XP_046671163.1 P04412 R-DME-416476 G alpha (q) signalling events XP_046671163.1 P04412 R-DME-416572 Sema4D induced cell migration and growth-cone collapse XP_046671163.1 P04412 R-DME-422475 Axon guidance XP_046671163.1 P04412 R-DME-445144 Signal transduction by L1 XP_046671163.1 P04412 R-DME-5653656 Vesicle-mediated transport XP_046671163.1 P04412 R-DME-5673001 RAF/MAP kinase cascade XP_046671163.1 P04412 R-DME-5683057 MAPK family signaling cascades XP_046671163.1 P04412 R-DME-5684996 MAPK1/MAPK3 signaling XP_046671163.1 P04412 R-DME-6785631 ERBB2 Regulates Cell Motility XP_046671163.1 P04412 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046671163.1 P04412 R-DME-881907 Gastrin-CREB signalling pathway via PKC and MAPK XP_046671163.1 P04412 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046671163.1 P04412 R-DME-8856828 Clathrin-mediated endocytosis XP_046671163.1 P04412 R-DME-8863795 Downregulation of ERBB2 signaling XP_046671163.1 P04412 R-DME-8939211 ESR-mediated signaling XP_046671163.1 P04412 R-DME-9006925 Intracellular signaling by second messengers XP_046671163.1 P04412 R-DME-9006931 Signaling by Nuclear Receptors XP_046671163.1 P04412 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046671163.1 P04412 R-DME-9018519 Estrogen-dependent gene expression XP_046671163.1 P04412 R-DME-9652282 Drug-mediated inhibition of ERBB2 signaling XP_046671163.1 P04412 R-DME-9675108 Nervous system development XP_046681385.1 Q9W2E7 R-DME-1430728 Metabolism XP_046681385.1 Q9W2E7 R-DME-1483249 Inositol phosphate metabolism XP_046681385.1 Q9W2E7 R-DME-159227 Transport of the SLBP independent Mature mRNA XP_046681385.1 Q9W2E7 R-DME-159230 Transport of the SLBP Dependant Mature mRNA XP_046681385.1 Q9W2E7 R-DME-159231 Transport of Mature mRNA Derived from an Intronless Transcript XP_046681385.1 Q9W2E7 R-DME-159234 Transport of Mature mRNAs Derived from Intronless Transcripts XP_046681385.1 Q9W2E7 R-DME-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript XP_046681385.1 Q9W2E7 R-DME-1640170 Cell Cycle XP_046681385.1 Q9W2E7 R-DME-1855170 IPs transport between nucleus and cytosol XP_046681385.1 Q9W2E7 R-DME-1855196 IP3 and IP4 transport between cytosol and nucleus XP_046681385.1 Q9W2E7 R-DME-1855229 IP6 and IP7 transport between cytosol and nucleus XP_046681385.1 Q9W2E7 R-DME-2262752 Cellular responses to stress XP_046681385.1 Q9W2E7 R-DME-2980766 Nuclear Envelope Breakdown XP_046681385.1 Q9W2E7 R-DME-2990846 SUMOylation XP_046681385.1 Q9W2E7 R-DME-3108214 SUMOylation of DNA damage response and repair proteins XP_046681385.1 Q9W2E7 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046681385.1 Q9W2E7 R-DME-3301854 Nuclear Pore Complex (NPC) Disassembly XP_046681385.1 Q9W2E7 R-DME-3371453 Regulation of HSF1-mediated heat shock response XP_046681385.1 Q9W2E7 R-DME-3371556 Cellular response to heat stress XP_046681385.1 Q9W2E7 R-DME-392499 Metabolism of proteins XP_046681385.1 Q9W2E7 R-DME-4085377 SUMOylation of SUMOylation proteins XP_046681385.1 Q9W2E7 R-DME-4551638 SUMOylation of chromatin organization proteins XP_046681385.1 Q9W2E7 R-DME-4615885 SUMOylation of DNA replication proteins XP_046681385.1 Q9W2E7 R-DME-597592 Post-translational protein modification XP_046681385.1 Q9W2E7 R-DME-68875 Mitotic Prophase XP_046681385.1 Q9W2E7 R-DME-68886 M Phase XP_046681385.1 Q9W2E7 R-DME-69278 Cell Cycle, Mitotic XP_046681385.1 Q9W2E7 R-DME-72202 Transport of Mature Transcript to Cytoplasm XP_046681385.1 Q9W2E7 R-DME-72203 Processing of Capped Intron-Containing Pre-mRNA XP_046681385.1 Q9W2E7 R-DME-8953854 Metabolism of RNA XP_046681385.1 Q9W2E7 R-DME-8953897 Cellular responses to stimuli XP_046668512.1 Q5U0V7 R-DME-1430728 Metabolism XP_046668512.1 Q5U0V7 R-DME-1483249 Inositol phosphate metabolism XP_046668512.1 Q5U0V7 R-DME-1483255 PI Metabolism XP_046668512.1 Q5U0V7 R-DME-1483257 Phospholipid metabolism XP_046668512.1 Q5U0V7 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046668512.1 Q5U0V7 R-DME-1855183 Synthesis of IP2, IP, and Ins in the cytosol XP_046668512.1 Q5U0V7 R-DME-1855204 Synthesis of IP3 and IP4 in the cytosol XP_046668512.1 Q5U0V7 R-DME-199991 Membrane Trafficking XP_046668512.1 Q5U0V7 R-DME-556833 Metabolism of lipids XP_046668512.1 Q5U0V7 R-DME-5653656 Vesicle-mediated transport XP_046668512.1 Q5U0V7 R-DME-8856828 Clathrin-mediated endocytosis XP_046687239.1 Q8MLS2 R-DME-1430728 Metabolism XP_046687239.1 Q8MLS2 R-DME-71336 Pentose phosphate pathway XP_046687239.1 Q8MLS2 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046680141.1 Q9W1N3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046680141.1 Q9W1N3 R-DME-1430728 Metabolism XP_046680141.1 Q9W1N3 R-DME-212436 Generic Transcription Pathway XP_046680141.1 Q9W1N3 R-DME-2262752 Cellular responses to stress XP_046680141.1 Q9W1N3 R-DME-3700989 Transcriptional Regulation by TP53 XP_046680141.1 Q9W1N3 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046680141.1 Q9W1N3 R-DME-611105 Respiratory electron transport XP_046680141.1 Q9W1N3 R-DME-73857 RNA Polymerase II Transcription XP_046680141.1 Q9W1N3 R-DME-74160 Gene expression (Transcription) XP_046680141.1 Q9W1N3 R-DME-8953897 Cellular responses to stimuli XP_046680141.1 Q9W1N3 R-DME-9707564 Cytoprotection by HMOX1 XP_046680141.1 Q9W1N3 R-DME-9711123 Cellular response to chemical stress XP_046680141.1 Q9W1N3 R-DME-9864848 Complex IV assembly XP_046667715.1 O02002 R-DME-109581 Apoptosis XP_046667715.1 O02002 R-DME-109606 Intrinsic Pathway for Apoptosis XP_046667715.1 O02002 R-DME-111459 Activation of caspases through apoptosome-mediated cleavage XP_046667715.1 O02002 R-DME-111461 Cytochrome c-mediated apoptotic response XP_046667715.1 O02002 R-DME-111465 Apoptotic cleavage of cellular proteins XP_046667715.1 O02002 R-DME-111469 SMAC, XIAP-regulated apoptotic response XP_046667715.1 O02002 R-DME-111471 Apoptotic factor-mediated response XP_046667715.1 O02002 R-DME-1280215 Cytokine Signaling in Immune system XP_046667715.1 O02002 R-DME-140342 Apoptosis induced DNA fragmentation XP_046667715.1 O02002 R-DME-140534 Caspase activation via Death Receptors in the presence of ligand XP_046667715.1 O02002 R-DME-162582 Signal Transduction XP_046667715.1 O02002 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046667715.1 O02002 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046667715.1 O02002 R-DME-166166 MyD88-independent TLR4 cascade XP_046667715.1 O02002 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046667715.1 O02002 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046667715.1 O02002 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046667715.1 O02002 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046667715.1 O02002 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046667715.1 O02002 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046667715.1 O02002 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046667715.1 O02002 R-DME-168249 Innate Immune System XP_046667715.1 O02002 R-DME-168256 Immune System XP_046667715.1 O02002 R-DME-168898 Toll-like Receptor Cascades XP_046667715.1 O02002 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046667715.1 O02002 R-DME-2028269 Signaling by Hippo XP_046667715.1 O02002 R-DME-264870 Caspase-mediated cleavage of cytoskeletal proteins XP_046667715.1 O02002 R-DME-3371378 Regulation by c-FLIP XP_046667715.1 O02002 R-DME-351906 Apoptotic cleavage of cell adhesion proteins XP_046667715.1 O02002 R-DME-352238 Breakdown of the nuclear lamina XP_046667715.1 O02002 R-DME-418889 Caspase activation via Dependence Receptors in the absence of ligand XP_046667715.1 O02002 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046667715.1 O02002 R-DME-446652 Interleukin-1 family signaling XP_046667715.1 O02002 R-DME-449147 Signaling by Interleukins XP_046667715.1 O02002 R-DME-5213460 RIPK1-mediated regulated necrosis XP_046667715.1 O02002 R-DME-5218859 Regulated Necrosis XP_046667715.1 O02002 R-DME-5218900 CASP8 activity is inhibited XP_046667715.1 O02002 R-DME-5357769 Caspase activation via extrinsic apoptotic signalling pathway XP_046667715.1 O02002 R-DME-5357801 Programmed Cell Death XP_046667715.1 O02002 R-DME-5357905 Regulation of TNFR1 signaling XP_046667715.1 O02002 R-DME-5675482 Regulation of necroptotic cell death XP_046667715.1 O02002 R-DME-69416 Dimerization of procaspase-8 XP_046667715.1 O02002 R-DME-73887 Death Receptor Signaling XP_046667715.1 O02002 R-DME-75153 Apoptotic execution phase XP_046667715.1 O02002 R-DME-75893 TNF signaling XP_046667715.1 O02002 R-DME-9020702 Interleukin-1 signaling XP_046667715.1 O02002 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046667715.1 O02002 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046667715.1 O02002 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046667715.1 O02002 R-DME-9758274 Regulation of NF-kappa B signaling XP_046667715.1 O02002 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046670261.1 Q27333 R-DME-392499 Metabolism of proteins XP_046670261.1 Q27333 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046670261.1 Q27333 R-DME-446203 Asparagine N-linked glycosylation XP_046670261.1 Q27333 R-DME-597592 Post-translational protein modification XP_046676081.1 P27091 R-DME-109582 Hemostasis XP_046676081.1 P27091 R-DME-114608 Platelet degranulation XP_046676081.1 P27091 R-DME-76002 Platelet activation, signaling and aggregation XP_046676081.1 P27091 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046673638.1 O77459 R-DME-209405 JAK/STAT pathway XP_046673638.1 O77459 R-DME-210671 Transcriptional repression by nuclear factors XP_046673638.1 O77459 R-DME-4839726 Chromatin organization XP_046673638.1 O77459 R-DME-5252538 Drosophila signaling pathways XP_046673638.1 O77459 R-DME-9932444 ATP-dependent chromatin remodelers XP_046673638.1 O77459 R-DME-9932451 SWI/SNF chromatin remodelers XP_046673638.1 O77459 R-DME-9933946 Formation of the embryonic stem cell BAF (esBAF) complex XP_046673638.1 O77459 R-DME-9934037 Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) XP_046666114.1 Q9W1G0 R-DME-1430728 Metabolism XP_046666114.1 Q9W1G0 R-DME-163685 Integration of energy metabolism XP_046666114.1 Q9W1G0 R-DME-163754 Insulin effects increased synthesis of Xylulose-5-Phosphate XP_046666114.1 Q9W1G0 R-DME-71336 Pentose phosphate pathway XP_046666114.1 Q9W1G0 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682106.1 O18680 R-DME-1430728 Metabolism XP_046682106.1 O18680 R-DME-189445 Metabolism of porphyrins XP_046682106.1 O18680 R-DME-189451 Heme biosynthesis XP_046682106.1 O18680 R-DME-392499 Metabolism of proteins XP_046682106.1 O18680 R-DME-9837999 Mitochondrial protein degradation XP_046672978.1 Q45VV3 R-DME-1236394 Signaling by ERBB4 XP_046672978.1 Q45VV3 R-DME-1251985 Nuclear signaling by ERBB4 XP_046672978.1 Q45VV3 R-DME-162582 Signal Transduction XP_046672978.1 Q45VV3 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046672978.1 Q45VV3 R-DME-2028269 Signaling by Hippo XP_046672978.1 Q45VV3 R-DME-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression XP_046672978.1 Q45VV3 R-DME-212436 Generic Transcription Pathway XP_046672978.1 Q45VV3 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046672978.1 Q45VV3 R-DME-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription XP_046672978.1 Q45VV3 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046672978.1 Q45VV3 R-DME-390146 Hippo/Warts pathway XP_046672978.1 Q45VV3 R-DME-390150 DS ligand bound to FT receptor XP_046672978.1 Q45VV3 R-DME-390178 DS ligand not bound to FT receptor XP_046672978.1 Q45VV3 R-DME-390193 Transcriptional activation by YKI XP_046672978.1 Q45VV3 R-DME-451806 Phosphorylation-independent inhibition of YKI XP_046672978.1 Q45VV3 R-DME-5252538 Drosophila signaling pathways XP_046672978.1 Q45VV3 R-DME-73857 RNA Polymerase II Transcription XP_046672978.1 Q45VV3 R-DME-74160 Gene expression (Transcription) XP_046672978.1 Q45VV3 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046672978.1 Q45VV3 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046672978.1 Q45VV3 R-DME-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs XP_046672978.1 Q45VV3 R-DME-8951671 RUNX3 regulates YAP1-mediated transcription XP_046672978.1 Q45VV3 R-DME-8953897 Cellular responses to stimuli XP_046672978.1 Q45VV3 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046672978.1 Q45VV3 R-DME-9006936 Signaling by TGFB family members XP_046672978.1 Q45VV3 R-DME-9855142 Cellular responses to mechanical stimuli XP_046672978.1 Q45VV3 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046672978.1 Q45VV3 R-DME-9860931 Response of endothelial cells to shear stress XP_046659101.1 Q9W1F5 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659101.1 Q9W1F5 R-DME-1430728 Metabolism XP_046659101.1 Q9W1F5 R-DME-189445 Metabolism of porphyrins XP_046659101.1 Q9W1F5 R-DME-189451 Heme biosynthesis XP_046659101.1 Q9W1F5 R-DME-611105 Respiratory electron transport XP_046659101.1 Q9W1F5 R-DME-9864848 Complex IV assembly XP_046659660.1 Q9W125 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659660.1 Q9W125 R-DME-1430728 Metabolism XP_046659660.1 Q9W125 R-DME-611105 Respiratory electron transport XP_046659660.1 Q9W125 R-DME-6799198 Complex I biogenesis XP_046661017.1 Q9W141 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046661017.1 Q9W141 R-DME-1430728 Metabolism XP_046661017.1 Q9W141 R-DME-1592230 Mitochondrial biogenesis XP_046661017.1 Q9W141 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046661017.1 Q9W141 R-DME-1852241 Organelle biogenesis and maintenance XP_046661017.1 Q9W141 R-DME-8949613 Cristae formation XP_046661937.1 Q9GYV5 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046661937.1 Q9GYV5 R-DME-1169091 Activation of NF-kappaB in B cells XP_046661937.1 Q9GYV5 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046661937.1 Q9GYV5 R-DME-1280215 Cytokine Signaling in Immune system XP_046661937.1 Q9GYV5 R-DME-1280218 Adaptive Immune System XP_046661937.1 Q9GYV5 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046661937.1 Q9GYV5 R-DME-162582 Signal Transduction XP_046661937.1 Q9GYV5 R-DME-1632852 Macroautophagy XP_046661937.1 Q9GYV5 R-DME-1640170 Cell Cycle XP_046661937.1 Q9GYV5 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046661937.1 Q9GYV5 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046661937.1 Q9GYV5 R-DME-166166 MyD88-independent TLR4 cascade XP_046661937.1 Q9GYV5 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046661937.1 Q9GYV5 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046661937.1 Q9GYV5 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046661937.1 Q9GYV5 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046661937.1 Q9GYV5 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046661937.1 Q9GYV5 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046661937.1 Q9GYV5 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046661937.1 Q9GYV5 R-DME-168249 Innate Immune System XP_046661937.1 Q9GYV5 R-DME-168256 Immune System XP_046661937.1 Q9GYV5 R-DME-168898 Toll-like Receptor Cascades XP_046661937.1 Q9GYV5 R-DME-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta XP_046661937.1 Q9GYV5 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046661937.1 Q9GYV5 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046661937.1 Q9GYV5 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046661937.1 Q9GYV5 R-DME-199991 Membrane Trafficking XP_046661937.1 Q9GYV5 R-DME-202403 TCR signaling XP_046661937.1 Q9GYV5 R-DME-202424 Downstream TCR signaling XP_046661937.1 Q9GYV5 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046661937.1 Q9GYV5 R-DME-209459 Imd pathway XP_046661937.1 Q9GYV5 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046661937.1 Q9GYV5 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046661937.1 Q9GYV5 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046661937.1 Q9GYV5 R-DME-2565942 Regulation of PLK1 Activity at G2/M Transition XP_046661937.1 Q9GYV5 R-DME-2871837 FCERI mediated NF-kB activation XP_046661937.1 Q9GYV5 R-DME-392499 Metabolism of proteins XP_046661937.1 Q9GYV5 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046661937.1 Q9GYV5 R-DME-446652 Interleukin-1 family signaling XP_046661937.1 Q9GYV5 R-DME-449147 Signaling by Interleukins XP_046661937.1 Q9GYV5 R-DME-453274 Mitotic G2-G2/M phases XP_046661937.1 Q9GYV5 R-DME-5205647 Mitophagy XP_046661937.1 Q9GYV5 R-DME-5205685 PINK1-PRKN Mediated Mitophagy XP_046661937.1 Q9GYV5 R-DME-5252538 Drosophila signaling pathways XP_046661937.1 Q9GYV5 R-DME-5357905 Regulation of TNFR1 signaling XP_046661937.1 Q9GYV5 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046661937.1 Q9GYV5 R-DME-5621481 C-type lectin receptors (CLRs) XP_046661937.1 Q9GYV5 R-DME-5653656 Vesicle-mediated transport XP_046661937.1 Q9GYV5 R-DME-5688426 Deubiquitination XP_046661937.1 Q9GYV5 R-DME-5689880 Ub-specific processing proteases XP_046661937.1 Q9GYV5 R-DME-597592 Post-translational protein modification XP_046661937.1 Q9GYV5 R-DME-69275 G2/M Transition XP_046661937.1 Q9GYV5 R-DME-69278 Cell Cycle, Mitotic XP_046661937.1 Q9GYV5 R-DME-73887 Death Receptor Signaling XP_046661937.1 Q9GYV5 R-DME-75893 TNF signaling XP_046661937.1 Q9GYV5 R-DME-8854214 TBC/RABGAPs XP_046661937.1 Q9GYV5 R-DME-8953897 Cellular responses to stimuli XP_046661937.1 Q9GYV5 R-DME-9007101 Rab regulation of trafficking XP_046661937.1 Q9GYV5 R-DME-9020702 Interleukin-1 signaling XP_046661937.1 Q9GYV5 R-DME-913531 Interferon Signaling XP_046661937.1 Q9GYV5 R-DME-933542 TRAF6 mediated NF-kB activation XP_046661937.1 Q9GYV5 R-DME-937039 IRAK1 recruits IKK complex XP_046661937.1 Q9GYV5 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046661937.1 Q9GYV5 R-DME-9612973 Autophagy XP_046661937.1 Q9GYV5 R-DME-9663891 Selective autophagy XP_046661937.1 Q9GYV5 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046661937.1 Q9GYV5 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046661937.1 Q9GYV5 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046661937.1 Q9GYV5 R-DME-9758274 Regulation of NF-kappa B signaling XP_046661937.1 Q9GYV5 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046661937.1 Q9GYV5 R-DME-9833482 PKR-mediated signaling XP_046661937.1 Q9GYV5 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046661937.1 Q9GYV5 R-DME-9855142 Cellular responses to mechanical stimuli XP_046661937.1 Q9GYV5 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046661937.1 Q9GYV5 R-DME-9860931 Response of endothelial cells to shear stress XP_046661937.1 Q9GYV5 R-DME-9909505 Modulation of host responses by IFN-stimulated genes XP_046685441.1 Q9W111 R-DME-162582 Signal Transduction XP_046685441.1 Q9W111 R-DME-177929 Signaling by EGFR XP_046685441.1 Q9W111 R-DME-182971 EGFR downregulation XP_046685441.1 Q9W111 R-DME-199991 Membrane Trafficking XP_046685441.1 Q9W111 R-DME-5653656 Vesicle-mediated transport XP_046685441.1 Q9W111 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046685441.1 Q9W111 R-DME-8856828 Clathrin-mediated endocytosis XP_046685441.1 Q9W111 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046668358.1 Q9GU23 R-DME-392499 Metabolism of proteins XP_046668358.1 Q9GU23 R-DME-4085001 Sialic acid metabolism XP_046668358.1 Q9GU23 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046668358.1 Q9GU23 R-DME-446203 Asparagine N-linked glycosylation XP_046668358.1 Q9GU23 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046668358.1 Q9GU23 R-DME-5173105 O-linked glycosylation XP_046668358.1 Q9GU23 R-DME-597592 Post-translational protein modification XP_046668358.1 Q9GU23 R-DME-913709 O-linked glycosylation of mucins XP_046668358.1 Q9GU23 R-DME-948021 Transport to the Golgi and subsequent modification XP_046668358.1 Q9GU23 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046668358.1 Q9GU23 R-DME-975577 N-Glycan antennae elongation XP_046668358.1 Q9GU23 R-DME-977068 Termination of O-glycan biosynthesis XP_046660361.1 Q9W0V1 R-DME-109582 Hemostasis XP_046660361.1 Q9W0V1 R-DME-109704 PI3K Cascade XP_046660361.1 Q9W0V1 R-DME-110478 Insulin signaling pathway XP_046660361.1 Q9W0V1 R-DME-110523 TOR signaling pathway XP_046660361.1 Q9W0V1 R-DME-110526 Insulin receptor mediated signaling XP_046660361.1 Q9W0V1 R-DME-112399 IRS-mediated signalling XP_046660361.1 Q9W0V1 R-DME-114604 GPVI-mediated activation cascade XP_046660361.1 Q9W0V1 R-DME-1257604 PIP3 activates AKT signaling XP_046660361.1 Q9W0V1 R-DME-1280218 Adaptive Immune System XP_046660361.1 Q9W0V1 R-DME-162582 Signal Transduction XP_046660361.1 Q9W0V1 R-DME-165158 Activation of AKT2 XP_046660361.1 Q9W0V1 R-DME-168249 Innate Immune System XP_046660361.1 Q9W0V1 R-DME-168256 Immune System XP_046660361.1 Q9W0V1 R-DME-194138 Signaling by VEGF XP_046660361.1 Q9W0V1 R-DME-194315 Signaling by Rho GTPases XP_046660361.1 Q9W0V1 R-DME-195258 RHO GTPase Effectors XP_046660361.1 Q9W0V1 R-DME-202403 TCR signaling XP_046660361.1 Q9W0V1 R-DME-202424 Downstream TCR signaling XP_046660361.1 Q9W0V1 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046660361.1 Q9W0V1 R-DME-2428924 IGF1R signaling cascade XP_046660361.1 Q9W0V1 R-DME-2428928 IRS-related events triggered by IGF1R XP_046660361.1 Q9W0V1 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046660361.1 Q9W0V1 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046660361.1 Q9W0V1 R-DME-354192 Integrin signaling XP_046660361.1 Q9W0V1 R-DME-372790 Signaling by GPCR XP_046660361.1 Q9W0V1 R-DME-388396 GPCR downstream signalling XP_046660361.1 Q9W0V1 R-DME-388841 Regulation of T cell activation by CD28 family XP_046660361.1 Q9W0V1 R-DME-389356 Co-stimulation by CD28 XP_046660361.1 Q9W0V1 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046660361.1 Q9W0V1 R-DME-392451 G beta:gamma signalling through PI3Kgamma XP_046660361.1 Q9W0V1 R-DME-397795 G-protein beta:gamma signalling XP_046660361.1 Q9W0V1 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046660361.1 Q9W0V1 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046660361.1 Q9W0V1 R-DME-5218921 VEGFR2 mediated cell proliferation XP_046660361.1 Q9W0V1 R-DME-5252538 Drosophila signaling pathways XP_046660361.1 Q9W0V1 R-DME-5625740 RHO GTPases activate PKNs XP_046660361.1 Q9W0V1 R-DME-74751 Insulin receptor signalling cascade XP_046660361.1 Q9W0V1 R-DME-74752 Signaling by Insulin receptor XP_046660361.1 Q9W0V1 R-DME-76002 Platelet activation, signaling and aggregation XP_046660361.1 Q9W0V1 R-DME-76009 Platelet Aggregation (Plug Formation) XP_046660361.1 Q9W0V1 R-DME-8939211 ESR-mediated signaling XP_046660361.1 Q9W0V1 R-DME-8953897 Cellular responses to stimuli XP_046660361.1 Q9W0V1 R-DME-9006925 Intracellular signaling by second messengers XP_046660361.1 Q9W0V1 R-DME-9006931 Signaling by Nuclear Receptors XP_046660361.1 Q9W0V1 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660361.1 Q9W0V1 R-DME-9009391 Extra-nuclear estrogen signaling XP_046660361.1 Q9W0V1 R-DME-9634635 Estrogen-stimulated signaling through PRKCZ XP_046660361.1 Q9W0V1 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046660361.1 Q9W0V1 R-DME-9855142 Cellular responses to mechanical stimuli XP_046660361.1 Q9W0V1 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046660361.1 Q9W0V1 R-DME-9860931 Response of endothelial cells to shear stress XP_046665363.1 A0A6M3Q6U2 R-DME-212436 Generic Transcription Pathway XP_046665363.1 A0A6M3Q6U2 R-DME-3700989 Transcriptional Regulation by TP53 XP_046665363.1 A0A6M3Q6U2 R-DME-5633007 Regulation of TP53 Activity XP_046665363.1 A0A6M3Q6U2 R-DME-6804756 Regulation of TP53 Activity through Phosphorylation XP_046665363.1 A0A6M3Q6U2 R-DME-73857 RNA Polymerase II Transcription XP_046665363.1 A0A6M3Q6U2 R-DME-74160 Gene expression (Transcription) XP_046665363.1 A0A6M3Q6U2 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046665363.1 A0A6M3Q6U2 R-DME-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known XP_046661853.1 Q9W0P5 R-DME-1430728 Metabolism XP_046661853.1 Q9W0P5 R-DME-70370 Galactose catabolism XP_046661853.1 Q9W0P5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046668629.1 E8NHA2 R-DME-1280218 Adaptive Immune System XP_046668629.1 E8NHA2 R-DME-168256 Immune System XP_046668629.1 E8NHA2 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046668629.1 E8NHA2 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046680433.1 Q94519 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046680433.1 Q94519 R-DME-1430728 Metabolism XP_046680433.1 Q94519 R-DME-392499 Metabolism of proteins XP_046680433.1 Q94519 R-DME-556833 Metabolism of lipids XP_046680433.1 Q94519 R-DME-597592 Post-translational protein modification XP_046680433.1 Q94519 R-DME-611105 Respiratory electron transport XP_046680433.1 Q94519 R-DME-6799198 Complex I biogenesis XP_046680433.1 Q94519 R-DME-77289 Mitochondrial Fatty Acid Beta-Oxidation XP_046680433.1 Q94519 R-DME-8978868 Fatty acid metabolism XP_046680433.1 Q94519 R-DME-9857492 Protein lipoylation XP_046676798.1 Q9W0G4 R-DME-1430728 Metabolism XP_046676798.1 Q9W0G4 R-DME-189445 Metabolism of porphyrins XP_046676798.1 Q9W0G4 R-DME-189451 Heme biosynthesis XP_046660785.1 P40792 R-DME-109582 Hemostasis XP_046660785.1 P40792 R-DME-114604 GPVI-mediated activation cascade XP_046660785.1 P40792 R-DME-1266738 Developmental Biology XP_046660785.1 P40792 R-DME-1280218 Adaptive Immune System XP_046660785.1 P40792 R-DME-1433557 Signaling by SCF-KIT XP_046660785.1 P40792 R-DME-1500931 Cell-Cell communication XP_046660785.1 P40792 R-DME-162582 Signal Transduction XP_046660785.1 P40792 R-DME-168249 Innate Immune System XP_046660785.1 P40792 R-DME-168256 Immune System XP_046660785.1 P40792 R-DME-193648 NRAGE signals death through JNK XP_046660785.1 P40792 R-DME-193704 p75 NTR receptor-mediated signalling XP_046660785.1 P40792 R-DME-194138 Signaling by VEGF XP_046660785.1 P40792 R-DME-194315 Signaling by Rho GTPases XP_046660785.1 P40792 R-DME-195258 RHO GTPase Effectors XP_046660785.1 P40792 R-DME-195721 Signaling by WNT XP_046660785.1 P40792 R-DME-2029480 Fcgamma receptor (FCGR) dependent phagocytosis XP_046660785.1 P40792 R-DME-2029482 Regulation of actin dynamics for phagocytic cup formation XP_046660785.1 P40792 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046660785.1 P40792 R-DME-2172127 DAP12 interactions XP_046660785.1 P40792 R-DME-2424491 DAP12 signaling XP_046660785.1 P40792 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046660785.1 P40792 R-DME-2682334 EPH-Ephrin signaling XP_046660785.1 P40792 R-DME-2871796 FCERI mediated MAPK activation XP_046660785.1 P40792 R-DME-350376 Activation of RAC1:GTP by FZ:DSH complex XP_046660785.1 P40792 R-DME-350431 Planar Cell Polarity pathway XP_046660785.1 P40792 R-DME-373760 L1CAM interactions XP_046660785.1 P40792 R-DME-3858494 Beta-catenin independent WNT signaling XP_046660785.1 P40792 R-DME-388841 Regulation of T cell activation by CD28 family XP_046660785.1 P40792 R-DME-389356 Co-stimulation by CD28 XP_046660785.1 P40792 R-DME-389359 CD28 dependent Vav1 pathway XP_046660785.1 P40792 R-DME-3928662 EPHB-mediated forward signaling XP_046660785.1 P40792 R-DME-3928664 Ephrin signaling XP_046660785.1 P40792 R-DME-3928665 EPH-ephrin mediated repulsion of cells XP_046660785.1 P40792 R-DME-4086400 PCP/CE pathway XP_046660785.1 P40792 R-DME-418990 Adherens junctions interactions XP_046660785.1 P40792 R-DME-421270 Cell-cell junction organization XP_046660785.1 P40792 R-DME-422475 Axon guidance XP_046660785.1 P40792 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046660785.1 P40792 R-DME-445144 Signal transduction by L1 XP_046660785.1 P40792 R-DME-446728 Cell junction organization XP_046660785.1 P40792 R-DME-450736 Activation of Downstream Effectors XP_046660785.1 P40792 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046660785.1 P40792 R-DME-5252538 Drosophila signaling pathways XP_046660785.1 P40792 R-DME-5625740 RHO GTPases activate PKNs XP_046660785.1 P40792 R-DME-5625900 RHO GTPases activate CIT XP_046660785.1 P40792 R-DME-5627123 RHO GTPases activate PAKs XP_046660785.1 P40792 R-DME-5663213 RHO GTPases Activate WASPs and WAVEs XP_046660785.1 P40792 R-DME-5683057 MAPK family signaling cascades XP_046660785.1 P40792 R-DME-5687128 MAPK6/MAPK4 signaling XP_046660785.1 P40792 R-DME-6798695 Neutrophil degranulation XP_046660785.1 P40792 R-DME-73887 Death Receptor Signaling XP_046660785.1 P40792 R-DME-76002 Platelet activation, signaling and aggregation XP_046660785.1 P40792 R-DME-8848021 Signaling by PTK6 XP_046660785.1 P40792 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046660785.1 P40792 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046660785.1 P40792 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660785.1 P40792 R-DME-9012999 RHO GTPase cycle XP_046660785.1 P40792 R-DME-9013149 RAC1 GTPase cycle XP_046660785.1 P40792 R-DME-9013423 RAC3 GTPase cycle XP_046660785.1 P40792 R-DME-9675108 Nervous system development XP_046660785.1 P40792 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046660785.1 P40792 R-DME-9748784 Drug ADME XP_046660785.1 P40792 R-DME-9748787 Azathioprine ADME XP_046660785.1 P40792 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046660785.1 P40792 R-DME-9958810 SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) XP_046660785.1 P40792 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046666684.1 Q9W0C5 R-DME-1369007 Mitochondrial ABC transporters XP_046666684.1 Q9W0C5 R-DME-382551 Transport of small molecules XP_046666684.1 Q9W0C5 R-DME-382556 ABC-family protein mediated transport XP_046669154.1 Q24276 R-DME-109582 Hemostasis XP_046669154.1 Q24276 R-DME-114608 Platelet degranulation XP_046669154.1 Q24276 R-DME-1227986 Signaling by ERBB2 XP_046669154.1 Q24276 R-DME-162582 Signal Transduction XP_046669154.1 Q24276 R-DME-194315 Signaling by Rho GTPases XP_046669154.1 Q24276 R-DME-76002 Platelet activation, signaling and aggregation XP_046669154.1 Q24276 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046669154.1 Q24276 R-DME-8863795 Downregulation of ERBB2 signaling XP_046669154.1 Q24276 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046669154.1 Q24276 R-DME-9012999 RHO GTPase cycle XP_046669154.1 Q24276 R-DME-9013418 RHOBTB2 GTPase cycle XP_046669154.1 Q24276 R-DME-9652282 Drug-mediated inhibition of ERBB2 signaling XP_046669154.1 Q24276 R-DME-9706574 RHOBTB GTPase Cycle XP_046669154.1 Q24276 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046683987.1 Q9W092 R-DME-168249 Innate Immune System XP_046683987.1 Q9W092 R-DME-168256 Immune System XP_046683987.1 Q9W092 R-DME-189085 Digestion of dietary carbohydrate XP_046683987.1 Q9W092 R-DME-6798695 Neutrophil degranulation XP_046683987.1 Q9W092 R-DME-8935690 Digestion XP_046683987.1 Q9W092 R-DME-8963743 Digestion and absorption XP_046682795.1 P08645 R-DME-109582 Hemostasis XP_046682795.1 P08645 R-DME-1280218 Adaptive Immune System XP_046682795.1 P08645 R-DME-1430728 Metabolism XP_046682795.1 P08645 R-DME-162582 Signal Transduction XP_046682795.1 P08645 R-DME-163685 Integration of energy metabolism XP_046682795.1 P08645 R-DME-166520 Signaling by NTRKs XP_046682795.1 P08645 R-DME-168249 Innate Immune System XP_046682795.1 P08645 R-DME-168256 Immune System XP_046682795.1 P08645 R-DME-169893 Prolonged ERK activation events XP_046682795.1 P08645 R-DME-170968 Frs2-mediated activation XP_046682795.1 P08645 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046682795.1 P08645 R-DME-187687 Signalling to ERKs XP_046682795.1 P08645 R-DME-354192 Integrin signaling XP_046682795.1 P08645 R-DME-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion XP_046682795.1 P08645 R-DME-392517 Rap1 signalling XP_046682795.1 P08645 R-DME-422356 Regulation of insulin secretion XP_046682795.1 P08645 R-DME-6798695 Neutrophil degranulation XP_046682795.1 P08645 R-DME-76002 Platelet activation, signaling and aggregation XP_046682795.1 P08645 R-DME-76009 Platelet Aggregation (Plug Formation) XP_046682795.1 P08645 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046659916.1 Q7KVA1 R-DME-1430728 Metabolism XP_046659916.1 Q7KVA1 R-DME-1630316 Glycosaminoglycan metabolism XP_046659916.1 Q7KVA1 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046659916.1 Q7KVA1 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046665889.1 Q9VZZ9 R-DME-109704 PI3K Cascade XP_046665889.1 Q9VZZ9 R-DME-112399 IRS-mediated signalling XP_046665889.1 Q9VZZ9 R-DME-1227986 Signaling by ERBB2 XP_046665889.1 Q9VZZ9 R-DME-1257604 PIP3 activates AKT signaling XP_046665889.1 Q9VZZ9 R-DME-1266738 Developmental Biology XP_046665889.1 Q9VZZ9 R-DME-162582 Signal Transduction XP_046665889.1 Q9VZZ9 R-DME-168249 Innate Immune System XP_046665889.1 Q9VZZ9 R-DME-168256 Immune System XP_046665889.1 Q9VZZ9 R-DME-177929 Signaling by EGFR XP_046665889.1 Q9VZZ9 R-DME-180292 GAB1 signalosome XP_046665889.1 Q9VZZ9 R-DME-190236 Signaling by FGFR XP_046665889.1 Q9VZZ9 R-DME-1963642 PI3K events in ERBB2 signaling XP_046665889.1 Q9VZZ9 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046665889.1 Q9VZZ9 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046665889.1 Q9VZZ9 R-DME-2428924 IGF1R signaling cascade XP_046665889.1 Q9VZZ9 R-DME-2428928 IRS-related events triggered by IGF1R XP_046665889.1 Q9VZZ9 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046665889.1 Q9VZZ9 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046665889.1 Q9VZZ9 R-DME-422475 Axon guidance XP_046665889.1 Q9VZZ9 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046665889.1 Q9VZZ9 R-DME-5654689 PI-3K cascade:FGFR1 XP_046665889.1 Q9VZZ9 R-DME-5654695 PI-3K cascade:FGFR2 XP_046665889.1 Q9VZZ9 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046665889.1 Q9VZZ9 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046665889.1 Q9VZZ9 R-DME-5654710 PI-3K cascade:FGFR3 XP_046665889.1 Q9VZZ9 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046665889.1 Q9VZZ9 R-DME-5654720 PI-3K cascade:FGFR4 XP_046665889.1 Q9VZZ9 R-DME-5654736 Signaling by FGFR1 XP_046665889.1 Q9VZZ9 R-DME-5654738 Signaling by FGFR2 XP_046665889.1 Q9VZZ9 R-DME-5654741 Signaling by FGFR3 XP_046665889.1 Q9VZZ9 R-DME-5654743 Signaling by FGFR4 XP_046665889.1 Q9VZZ9 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046665889.1 Q9VZZ9 R-DME-74751 Insulin receptor signalling cascade XP_046665889.1 Q9VZZ9 R-DME-74752 Signaling by Insulin receptor XP_046665889.1 Q9VZZ9 R-DME-8853659 RET signaling XP_046665889.1 Q9VZZ9 R-DME-9006925 Intracellular signaling by second messengers XP_046665889.1 Q9VZZ9 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046665889.1 Q9VZZ9 R-DME-9675108 Nervous system development XP_046668340.1 Q9W002 R-DME-2262752 Cellular responses to stress XP_046668340.1 Q9W002 R-DME-2559580 Oxidative Stress Induced Senescence XP_046668340.1 Q9W002 R-DME-2559583 Cellular Senescence XP_046668340.1 Q9W002 R-DME-350376 Activation of RAC1:GTP by FZ:DSH complex XP_046668340.1 Q9W002 R-DME-350431 Planar Cell Polarity pathway XP_046668340.1 Q9W002 R-DME-450736 Activation of Downstream Effectors XP_046668340.1 Q9W002 R-DME-5252538 Drosophila signaling pathways XP_046668340.1 Q9W002 R-DME-8953897 Cellular responses to stimuli XP_046665614.1 Q6WV16 R-DME-392499 Metabolism of proteins XP_046665614.1 Q6WV16 R-DME-5173105 O-linked glycosylation XP_046665614.1 Q6WV16 R-DME-597592 Post-translational protein modification XP_046665614.1 Q6WV16 R-DME-913709 O-linked glycosylation of mucins XP_046667291.1 Q9V3Q4 R-DME-168249 Innate Immune System XP_046667291.1 Q9V3Q4 R-DME-168256 Immune System XP_046667291.1 Q9V3Q4 R-DME-6798695 Neutrophil degranulation XP_046669964.1 Q9VZU8 R-DME-392499 Metabolism of proteins XP_046669964.1 Q9VZU8 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046669964.1 Q9VZU8 R-DME-446203 Asparagine N-linked glycosylation XP_046669964.1 Q9VZU8 R-DME-597592 Post-translational protein modification XP_046689265.1 Q9VZU2 R-DME-162582 Signal Transduction XP_046689265.1 Q9VZU2 R-DME-209392 Hedgehog pathway XP_046689265.1 Q9VZU2 R-DME-209471 Formation and transport of the N-HH ligand XP_046689265.1 Q9VZU2 R-DME-5252538 Drosophila signaling pathways XP_046689265.1 Q9VZU2 R-DME-5358346 Hedgehog ligand biogenesis XP_046689265.1 Q9VZU2 R-DME-5358351 Signaling by Hedgehog XP_046669996.1 P02828 R-DME-1227986 Signaling by ERBB2 XP_046669996.1 P02828 R-DME-1266738 Developmental Biology XP_046669996.1 P02828 R-DME-1430728 Metabolism XP_046669996.1 P02828 R-DME-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation XP_046669996.1 P02828 R-DME-162582 Signal Transduction XP_046669996.1 P02828 R-DME-168249 Innate Immune System XP_046669996.1 P02828 R-DME-168256 Immune System XP_046669996.1 P02828 R-DME-194138 Signaling by VEGF XP_046669996.1 P02828 R-DME-194315 Signaling by Rho GTPases XP_046669996.1 P02828 R-DME-196854 Metabolism of vitamins and cofactors XP_046669996.1 P02828 R-DME-202131 Metabolism of nitric oxide: NOS3 activation and regulation XP_046669996.1 P02828 R-DME-2029480 Fcgamma receptor (FCGR) dependent phagocytosis XP_046669996.1 P02828 R-DME-2029482 Regulation of actin dynamics for phagocytic cup formation XP_046669996.1 P02828 R-DME-203615 eNOS activation XP_046669996.1 P02828 R-DME-211859 Biological oxidations XP_046669996.1 P02828 R-DME-211945 Phase I - Functionalization of compounds XP_046669996.1 P02828 R-DME-2262752 Cellular responses to stress XP_046669996.1 P02828 R-DME-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand XP_046669996.1 P02828 R-DME-3371511 HSF1 activation XP_046669996.1 P02828 R-DME-3371556 Cellular response to heat stress XP_046669996.1 P02828 R-DME-3371568 Attenuation phase XP_046669996.1 P02828 R-DME-3371571 HSF1-dependent transactivation XP_046669996.1 P02828 R-DME-373755 Semaphorin interactions XP_046669996.1 P02828 R-DME-399954 Sema3A PAK dependent Axon repulsion XP_046669996.1 P02828 R-DME-422475 Axon guidance XP_046669996.1 P02828 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046669996.1 P02828 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046669996.1 P02828 R-DME-6798695 Neutrophil degranulation XP_046669996.1 P02828 R-DME-8863795 Downregulation of ERBB2 signaling XP_046669996.1 P02828 R-DME-8937144 Aryl hydrocarbon receptor signalling XP_046669996.1 P02828 R-DME-8939211 ESR-mediated signaling XP_046669996.1 P02828 R-DME-8953897 Cellular responses to stimuli XP_046669996.1 P02828 R-DME-8978934 Metabolism of cofactors XP_046669996.1 P02828 R-DME-9006931 Signaling by Nuclear Receptors XP_046669996.1 P02828 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046669996.1 P02828 R-DME-9009391 Extra-nuclear estrogen signaling XP_046669996.1 P02828 R-DME-9012999 RHO GTPase cycle XP_046669996.1 P02828 R-DME-9013418 RHOBTB2 GTPase cycle XP_046669996.1 P02828 R-DME-9018519 Estrogen-dependent gene expression XP_046669996.1 P02828 R-DME-9652282 Drug-mediated inhibition of ERBB2 signaling XP_046669996.1 P02828 R-DME-9675108 Nervous system development XP_046669996.1 P02828 R-DME-9706574 RHOBTB GTPase Cycle XP_046669996.1 P02828 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046678020.1 Q9VZR0 R-DME-1430728 Metabolism XP_046678020.1 Q9VZR0 R-DME-196807 Nicotinate metabolism XP_046678020.1 Q9VZR0 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046678020.1 Q9VZR0 R-DME-196854 Metabolism of vitamins and cofactors XP_046672132.1 Q9VZP8 R-DME-1430728 Metabolism XP_046672132.1 Q9VZP8 R-DME-1630316 Glycosaminoglycan metabolism XP_046672132.1 Q9VZP8 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046672132.1 Q9VZP8 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046672132.1 Q9VZP8 R-DME-2024096 HS-GAG degradation XP_046672132.1 Q9VZP8 R-DME-2024101 CS/DS degradation XP_046672132.1 Q9VZP8 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046660823.1 Q9VZV2 R-DME-168249 Innate Immune System XP_046660823.1 Q9VZV2 R-DME-168256 Immune System XP_046660823.1 Q9VZV2 R-DME-189085 Digestion of dietary carbohydrate XP_046660823.1 Q9VZV2 R-DME-6798695 Neutrophil degranulation XP_046660823.1 Q9VZV2 R-DME-8935690 Digestion XP_046660823.1 Q9VZV2 R-DME-8963743 Digestion and absorption XP_046674290.1 O44783 R-DME-1295596 Spry regulation of FGF signaling XP_046674290.1 O44783 R-DME-162582 Signal Transduction XP_046674290.1 O44783 R-DME-177929 Signaling by EGFR XP_046674290.1 O44783 R-DME-182971 EGFR downregulation XP_046674290.1 O44783 R-DME-190236 Signaling by FGFR XP_046674290.1 O44783 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046674290.1 O44783 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046674290.1 O44783 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046674290.1 O44783 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046674290.1 O44783 R-DME-5654736 Signaling by FGFR1 XP_046674290.1 O44783 R-DME-5654738 Signaling by FGFR2 XP_046674290.1 O44783 R-DME-5654741 Signaling by FGFR3 XP_046674290.1 O44783 R-DME-5654743 Signaling by FGFR4 XP_046674290.1 O44783 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046688692.1 Q94522 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046688692.1 Q94522 R-DME-1430728 Metabolism XP_046688692.1 Q94522 R-DME-71403 Citric acid cycle (TCA cycle) XP_046678953.1 Q9VZF5 R-DME-109582 Hemostasis XP_046678953.1 Q9VZF5 R-DME-1640170 Cell Cycle XP_046678953.1 Q9VZF5 R-DME-68884 Mitotic Telophase/Cytokinesis XP_046678953.1 Q9VZF5 R-DME-68886 M Phase XP_046678953.1 Q9VZF5 R-DME-69278 Cell Cycle, Mitotic XP_046678953.1 Q9VZF5 R-DME-983189 Kinesins XP_046678953.1 Q9VZF5 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046666415.1 Q09024 R-DME-109582 Hemostasis XP_046666415.1 Q09024 R-DME-1266738 Developmental Biology XP_046666415.1 Q09024 R-DME-1474228 Degradation of the extracellular matrix XP_046666415.1 Q09024 R-DME-1474244 Extracellular matrix organization XP_046666415.1 Q09024 R-DME-202733 Cell surface interactions at the vascular wall XP_046666415.1 Q09024 R-DME-210991 Basigin interactions XP_046666415.1 Q09024 R-DME-216083 Integrin cell surface interactions XP_046666415.1 Q09024 R-DME-376176 Signaling by ROBO receptors XP_046666415.1 Q09024 R-DME-382551 Transport of small molecules XP_046666415.1 Q09024 R-DME-422475 Axon guidance XP_046666415.1 Q09024 R-DME-425407 SLC-mediated transmembrane transport XP_046666415.1 Q09024 R-DME-428542 Regulation of commissural axon pathfinding by SLIT and ROBO XP_046666415.1 Q09024 R-DME-433692 Proton-coupled monocarboxylate transport XP_046666415.1 Q09024 R-DME-9675108 Nervous system development XP_046666415.1 Q09024 R-DME-9748784 Drug ADME XP_046666415.1 Q09024 R-DME-9749641 Aspirin ADME XP_046666415.1 Q09024 R-DME-9955298 SLC-mediated transport of organic anions XP_046682867.1 M9PE88 R-DME-162582 Signal Transduction XP_046682867.1 M9PE88 R-DME-201451 Signaling by BMP XP_046682867.1 M9PE88 R-DME-9006936 Signaling by TGFB family members XP_046659277.1 Q94517 R-DME-109582 Hemostasis XP_046659277.1 Q94517 R-DME-1257604 PIP3 activates AKT signaling XP_046659277.1 Q94517 R-DME-1266738 Developmental Biology XP_046659277.1 Q94517 R-DME-1500931 Cell-Cell communication XP_046659277.1 Q94517 R-DME-1538133 G0 and Early G1 XP_046659277.1 Q94517 R-DME-162582 Signal Transduction XP_046659277.1 Q94517 R-DME-1640170 Cell Cycle XP_046659277.1 Q94517 R-DME-195721 Signaling by WNT XP_046659277.1 Q94517 R-DME-201556 Signaling by ALK XP_046659277.1 Q94517 R-DME-201681 TCF dependent signaling in response to WNT XP_046659277.1 Q94517 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046659277.1 Q94517 R-DME-209394 Transcriptional activtion and repression of REL-68 target genes XP_046659277.1 Q94517 R-DME-209459 Imd pathway XP_046659277.1 Q94517 R-DME-212436 Generic Transcription Pathway XP_046659277.1 Q94517 R-DME-3214815 HDACs deacetylate histones XP_046659277.1 Q94517 R-DME-3247509 Chromatin modifying enzymes XP_046659277.1 Q94517 R-DME-350054 Notch-HLH transcription pathway XP_046659277.1 Q94517 R-DME-3700989 Transcriptional Regulation by TP53 XP_046659277.1 Q94517 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046659277.1 Q94517 R-DME-418990 Adherens junctions interactions XP_046659277.1 Q94517 R-DME-421270 Cell-cell junction organization XP_046659277.1 Q94517 R-DME-446728 Cell junction organization XP_046659277.1 Q94517 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046659277.1 Q94517 R-DME-4839726 Chromatin organization XP_046659277.1 Q94517 R-DME-5252538 Drosophila signaling pathways XP_046659277.1 Q94517 R-DME-5633007 Regulation of TP53 Activity XP_046659277.1 Q94517 R-DME-6804758 Regulation of TP53 Activity through Acetylation XP_046659277.1 Q94517 R-DME-6807070 PTEN Regulation XP_046659277.1 Q94517 R-DME-69278 Cell Cycle, Mitotic XP_046659277.1 Q94517 R-DME-73857 RNA Polymerase II Transcription XP_046659277.1 Q94517 R-DME-74160 Gene expression (Transcription) XP_046659277.1 Q94517 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046659277.1 Q94517 R-DME-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function XP_046659277.1 Q94517 R-DME-8939211 ESR-mediated signaling XP_046659277.1 Q94517 R-DME-8943724 Regulation of PTEN gene transcription XP_046659277.1 Q94517 R-DME-9006925 Intracellular signaling by second messengers XP_046659277.1 Q94517 R-DME-9006931 Signaling by Nuclear Receptors XP_046659277.1 Q94517 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046659277.1 Q94517 R-DME-9018519 Estrogen-dependent gene expression XP_046659277.1 Q94517 R-DME-9701898 STAT3 nuclear events downstream of ALK signaling XP_046659277.1 Q94517 R-DME-9730414 MITF-M-regulated melanocyte development XP_046659277.1 Q94517 R-DME-9759476 Regulation of Homotypic Cell-Cell Adhesion XP_046659277.1 Q94517 R-DME-9764265 Regulation of CDH1 Expression and Function XP_046659277.1 Q94517 R-DME-9764274 Regulation of Expression and Function of Type I Classical Cadherins XP_046659277.1 Q94517 R-DME-9764560 Regulation of CDH1 Gene Transcription XP_046659277.1 Q94517 R-DME-9764725 Negative Regulation of CDH1 Gene Transcription XP_046659277.1 Q94517 R-DME-9824594 Regulation of MITF-M-dependent genes involved in apoptosis XP_046659277.1 Q94517 R-DME-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation XP_046659277.1 Q94517 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046659277.1 Q94517 R-DME-9856651 MITF-M-dependent gene expression XP_046659277.1 Q94517 R-DME-9932444 ATP-dependent chromatin remodelers XP_046659277.1 Q94517 R-DME-9937848 CHD chromatin remodelers XP_046659277.1 Q94517 R-DME-9937850 NuRD complex assembly XP_046659277.1 Q94517 R-DME-9940951 Interaction of NuRD complexes with transcription factors XP_046659277.1 Q94517 R-DME-9943965 CHD3, CHD4, CHD5 subfamily XP_046675967.1 Q9VZ64 R-DME-1430728 Metabolism XP_046675967.1 Q9VZ64 R-DME-71336 Pentose phosphate pathway XP_046675967.1 Q9VZ64 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046672893.1 P51140 R-DME-162582 Signal Transduction XP_046672893.1 P51140 R-DME-194315 Signaling by Rho GTPases XP_046672893.1 P51140 R-DME-195258 RHO GTPase Effectors XP_046672893.1 P51140 R-DME-195721 Signaling by WNT XP_046672893.1 P51140 R-DME-201681 TCF dependent signaling in response to WNT XP_046672893.1 P51140 R-DME-201688 WNT mediated activation of DVL XP_046672893.1 P51140 R-DME-2028269 Signaling by Hippo XP_046672893.1 P51140 R-DME-209412 Wingless pathway XP_046672893.1 P51140 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046672893.1 P51140 R-DME-209469 WG ligand bound to FZ receptors XP_046672893.1 P51140 R-DME-350368 Activation of RHO1 by FZ:DSH complex XP_046672893.1 P51140 R-DME-350369 Negative feedback loop regulates asymmetric localisation XP_046672893.1 P51140 R-DME-350376 Activation of RAC1:GTP by FZ:DSH complex XP_046672893.1 P51140 R-DME-350411 Formation and asymmetric localisation of transmembrane complexes XP_046672893.1 P51140 R-DME-350431 Planar Cell Polarity pathway XP_046672893.1 P51140 R-DME-350480 Activation of non-muscle Myosin II XP_046672893.1 P51140 R-DME-3858494 Beta-catenin independent WNT signaling XP_046672893.1 P51140 R-DME-4086400 PCP/CE pathway XP_046672893.1 P51140 R-DME-450728 Inhibition of actin polymerization XP_046672893.1 P51140 R-DME-450736 Activation of Downstream Effectors XP_046672893.1 P51140 R-DME-450799 RHO1 signalling XP_046672893.1 P51140 R-DME-4608870 Asymmetric localization of PCP proteins XP_046672893.1 P51140 R-DME-4641258 Degradation of DVL XP_046672893.1 P51140 R-DME-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane XP_046672893.1 P51140 R-DME-5099900 WNT5A-dependent internalization of FZD4 XP_046672893.1 P51140 R-DME-5252538 Drosophila signaling pathways XP_046672893.1 P51140 R-DME-5663220 RHO GTPases Activate Formins XP_046672893.1 P51140 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046670693.1 Q24592 R-DME-109582 Hemostasis XP_046670693.1 Q24592 R-DME-1266695 Interleukin-7 signaling XP_046670693.1 Q24592 R-DME-1280215 Cytokine Signaling in Immune system XP_046670693.1 Q24592 R-DME-162582 Signal Transduction XP_046670693.1 Q24592 R-DME-1640170 Cell Cycle XP_046670693.1 Q24592 R-DME-168256 Immune System XP_046670693.1 Q24592 R-DME-209209 Formation of the activated receptor complex XP_046670693.1 Q24592 R-DME-209228 Formation of the activated STAT92E dimer and transport to the nucleus XP_046670693.1 Q24592 R-DME-209405 JAK/STAT pathway XP_046670693.1 Q24592 R-DME-210688 Dephosphorylation by PTP61F phosphatases XP_046670693.1 Q24592 R-DME-449147 Signaling by Interleukins XP_046670693.1 Q24592 R-DME-451927 Interleukin-2 family signaling XP_046670693.1 Q24592 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046670693.1 Q24592 R-DME-5252538 Drosophila signaling pathways XP_046670693.1 Q24592 R-DME-5673000 RAF activation XP_046670693.1 Q24592 R-DME-5673001 RAF/MAP kinase cascade XP_046670693.1 Q24592 R-DME-5683057 MAPK family signaling cascades XP_046670693.1 Q24592 R-DME-5684996 MAPK1/MAPK3 signaling XP_046670693.1 Q24592 R-DME-6785807 Interleukin-4 and Interleukin-13 signaling XP_046670693.1 Q24592 R-DME-69231 Cyclin D associated events in G1 XP_046670693.1 Q24592 R-DME-69236 G1 Phase XP_046670693.1 Q24592 R-DME-69278 Cell Cycle, Mitotic XP_046670693.1 Q24592 R-DME-8985947 Interleukin-9 signaling XP_046670693.1 Q24592 R-DME-9020558 Interleukin-2 signaling XP_046670693.1 Q24592 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046682560.1 Q9VYX7 R-DME-168249 Innate Immune System XP_046682560.1 Q9VYX7 R-DME-168256 Immune System XP_046682560.1 Q9VYX7 R-DME-6798695 Neutrophil degranulation XP_046682560.1 Q9VYX7 R-DME-6803157 Antimicrobial peptides XP_046682181.1 O62589 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046682181.1 O62589 R-DME-209449 Toll pathway XP_046682181.1 O62589 R-DME-5252538 Drosophila signaling pathways XP_046669452.1 P29844 R-DME-2262752 Cellular responses to stress XP_046669452.1 P29844 R-DME-3371453 Regulation of HSF1-mediated heat shock response XP_046669452.1 P29844 R-DME-3371556 Cellular response to heat stress XP_046669452.1 P29844 R-DME-8953897 Cellular responses to stimuli XP_046665025.1 Q9VYV5 R-DME-392499 Metabolism of proteins XP_046665025.1 Q9VYV5 R-DME-446203 Asparagine N-linked glycosylation XP_046665025.1 Q9VYV5 R-DME-597592 Post-translational protein modification XP_046665025.1 Q9VYV5 R-DME-948021 Transport to the Golgi and subsequent modification XP_046665025.1 Q9VYV5 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046665025.1 Q9VYV5 R-DME-975578 Reactions specific to the complex N-glycan synthesis pathway XP_046660940.1 Q9VYQ8 R-DME-1257604 PIP3 activates AKT signaling XP_046660940.1 Q9VYQ8 R-DME-162582 Signal Transduction XP_046660940.1 Q9VYQ8 R-DME-212436 Generic Transcription Pathway XP_046660940.1 Q9VYQ8 R-DME-3700989 Transcriptional Regulation by TP53 XP_046660940.1 Q9VYQ8 R-DME-392499 Metabolism of proteins XP_046660940.1 Q9VYQ8 R-DME-5633007 Regulation of TP53 Activity XP_046660940.1 Q9VYQ8 R-DME-5688426 Deubiquitination XP_046660940.1 Q9VYQ8 R-DME-5689880 Ub-specific processing proteases XP_046660940.1 Q9VYQ8 R-DME-5696398 Nucleotide Excision Repair XP_046660940.1 Q9VYQ8 R-DME-597592 Post-translational protein modification XP_046660940.1 Q9VYQ8 R-DME-6781823 Formation of TC-NER Pre-Incision Complex XP_046660940.1 Q9VYQ8 R-DME-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) XP_046660940.1 Q9VYQ8 R-DME-6782135 Dual incision in TC-NER XP_046660940.1 Q9VYQ8 R-DME-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER XP_046660940.1 Q9VYQ8 R-DME-6804757 Regulation of TP53 Degradation XP_046660940.1 Q9VYQ8 R-DME-6806003 Regulation of TP53 Expression and Degradation XP_046660940.1 Q9VYQ8 R-DME-6807070 PTEN Regulation XP_046660940.1 Q9VYQ8 R-DME-73857 RNA Polymerase II Transcription XP_046660940.1 Q9VYQ8 R-DME-73894 DNA Repair XP_046660940.1 Q9VYQ8 R-DME-74160 Gene expression (Transcription) XP_046660940.1 Q9VYQ8 R-DME-8852135 Protein ubiquitination XP_046660940.1 Q9VYQ8 R-DME-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes XP_046660940.1 Q9VYQ8 R-DME-8948747 Regulation of PTEN localization XP_046660940.1 Q9VYQ8 R-DME-9006925 Intracellular signaling by second messengers XP_046667954.1 P54367 R-DME-162582 Signal Transduction XP_046667954.1 P54367 R-DME-1640170 Cell Cycle XP_046667954.1 P54367 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046667954.1 P54367 R-DME-195721 Signaling by WNT XP_046667954.1 P54367 R-DME-196299 Beta-catenin phosphorylation cascade XP_046667954.1 P54367 R-DME-209155 Phosphorylation of AXN and APC XP_046667954.1 P54367 R-DME-209159 Assembly of the CI containing complexes XP_046667954.1 P54367 R-DME-209190 Phosphorylation of CI XP_046667954.1 P54367 R-DME-209214 Phosphorylation of SMO XP_046667954.1 P54367 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046667954.1 P54367 R-DME-209392 Hedgehog pathway XP_046667954.1 P54367 R-DME-209396 Phosphorylation of ARM XP_046667954.1 P54367 R-DME-209412 Wingless pathway XP_046667954.1 P54367 R-DME-209413 Assembly of the 'destruction complex' XP_046667954.1 P54367 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046667954.1 P54367 R-DME-209441 WG ligand not bound to FZ receptors XP_046667954.1 P54367 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046667954.1 P54367 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046667954.1 P54367 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046667954.1 P54367 R-DME-209469 WG ligand bound to FZ receptors XP_046667954.1 P54367 R-DME-216217 Activation of SMO XP_046667954.1 P54367 R-DME-432553 Phosphorylation of PER and TIM XP_046667954.1 P54367 R-DME-432626 Circadian Clock pathway XP_046667954.1 P54367 R-DME-5252538 Drosophila signaling pathways XP_046667954.1 P54367 R-DME-5358351 Signaling by Hedgehog XP_046667954.1 P54367 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046667954.1 P54367 R-DME-5610787 Hedgehog 'off' state XP_046667954.1 P54367 R-DME-5632684 Hedgehog 'on' state XP_046667954.1 P54367 R-DME-5635838 Activation of SMO XP_046667954.1 P54367 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046667954.1 P54367 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046667954.1 P54367 R-DME-69615 G1/S DNA Damage Checkpoints XP_046667954.1 P54367 R-DME-69620 Cell Cycle Checkpoints XP_046685410.1 Q9VYI6 R-DME-1430728 Metabolism XP_046685410.1 Q9VYI6 R-DME-196854 Metabolism of vitamins and cofactors XP_046685410.1 Q9VYI6 R-DME-2142789 Ubiquinol biosynthesis XP_046685410.1 Q9VYI6 R-DME-8978934 Metabolism of cofactors XP_046668144.1 Q9VYF8 R-DME-1430728 Metabolism XP_046668144.1 Q9VYF8 R-DME-196854 Metabolism of vitamins and cofactors XP_046668144.1 Q9VYF8 R-DME-2142789 Ubiquinol biosynthesis XP_046668144.1 Q9VYF8 R-DME-8978934 Metabolism of cofactors XP_046676512.1 Q9VY77 R-DME-1234174 Cellular response to hypoxia XP_046676512.1 Q9VY77 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046676512.1 Q9VY77 R-DME-212165 Epigenetic regulation of gene expression XP_046676512.1 Q9VY77 R-DME-2262752 Cellular responses to stress XP_046676512.1 Q9VY77 R-DME-74160 Gene expression (Transcription) XP_046676512.1 Q9VY77 R-DME-8953897 Cellular responses to stimuli XP_046676512.1 Q9VY77 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046676512.1 Q9VY77 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046676512.1 Q9VY77 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046676512.1 Q9VY77 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046671791.1 Q9VYA0 R-DME-1430728 Metabolism XP_046671791.1 Q9VYA0 R-DME-196807 Nicotinate metabolism XP_046671791.1 Q9VYA0 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046671791.1 Q9VYA0 R-DME-196854 Metabolism of vitamins and cofactors XP_046661585.1 P35128 R-DME-1280215 Cytokine Signaling in Immune system XP_046661585.1 P35128 R-DME-1280218 Adaptive Immune System XP_046661585.1 P35128 R-DME-1632852 Macroautophagy XP_046661585.1 P35128 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046661585.1 P35128 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046661585.1 P35128 R-DME-166166 MyD88-independent TLR4 cascade XP_046661585.1 P35128 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046661585.1 P35128 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046661585.1 P35128 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046661585.1 P35128 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046661585.1 P35128 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046661585.1 P35128 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046661585.1 P35128 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046661585.1 P35128 R-DME-168249 Innate Immune System XP_046661585.1 P35128 R-DME-168256 Immune System XP_046661585.1 P35128 R-DME-168898 Toll-like Receptor Cascades XP_046661585.1 P35128 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046661585.1 P35128 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046661585.1 P35128 R-DME-209459 Imd pathway XP_046661585.1 P35128 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046661585.1 P35128 R-DME-446652 Interleukin-1 family signaling XP_046661585.1 P35128 R-DME-449147 Signaling by Interleukins XP_046661585.1 P35128 R-DME-5205647 Mitophagy XP_046661585.1 P35128 R-DME-5205685 PINK1-PRKN Mediated Mitophagy XP_046661585.1 P35128 R-DME-5252538 Drosophila signaling pathways XP_046661585.1 P35128 R-DME-9020702 Interleukin-1 signaling XP_046661585.1 P35128 R-DME-937039 IRAK1 recruits IKK complex XP_046661585.1 P35128 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046661585.1 P35128 R-DME-9612973 Autophagy XP_046661585.1 P35128 R-DME-9646399 Aggrephagy XP_046661585.1 P35128 R-DME-9663891 Selective autophagy XP_046661585.1 P35128 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046661585.1 P35128 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046661585.1 P35128 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046661585.1 P35128 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046661585.1 P35128 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046661585.1 P35128 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046664479.1 Q9VXZ0 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046664479.1 Q9VXZ0 R-DME-1430728 Metabolism XP_046664479.1 Q9VXZ0 R-DME-611105 Respiratory electron transport XP_046664479.1 Q9VXZ0 R-DME-6799198 Complex I biogenesis XP_046664512.1 Q8SXQ5 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046664512.1 Q8SXQ5 R-DME-1430728 Metabolism XP_046682828.1 Q05547 R-DME-432626 Circadian Clock pathway XP_046682828.1 Q05547 R-DME-5252538 Drosophila signaling pathways XP_046682828.1 Q05547 R-DME-538898 Dephosphorylation of TIM XP_046682828.1 Q05547 R-DME-72187 mRNA 3'-end processing XP_046682828.1 Q05547 R-DME-72203 Processing of Capped Intron-Containing Pre-mRNA XP_046682828.1 Q05547 R-DME-8953854 Metabolism of RNA XP_046682828.1 Q05547 R-DME-9770562 mRNA Polyadenylation XP_046663733.1 Q9VXU7 R-DME-392499 Metabolism of proteins XP_046663733.1 Q9VXU7 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046663733.1 Q9VXU7 R-DME-446203 Asparagine N-linked glycosylation XP_046663733.1 Q9VXU7 R-DME-597592 Post-translational protein modification XP_046683361.1 X2JF73 R-DME-1280218 Adaptive Immune System XP_046683361.1 X2JF73 R-DME-1500931 Cell-Cell communication XP_046683361.1 X2JF73 R-DME-168249 Innate Immune System XP_046683361.1 X2JF73 R-DME-168256 Immune System XP_046683361.1 X2JF73 R-DME-418990 Adherens junctions interactions XP_046683361.1 X2JF73 R-DME-421270 Cell-cell junction organization XP_046683361.1 X2JF73 R-DME-446728 Cell junction organization XP_046683361.1 X2JF73 R-DME-6798695 Neutrophil degranulation XP_046683361.1 X2JF73 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046683361.1 X2JF73 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046683361.1 X2JF73 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046672578.1 P26308 R-DME-109582 Hemostasis XP_046672578.1 P26308 R-DME-112314 Neurotransmitter receptors and postsynaptic signal transmission XP_046672578.1 P26308 R-DME-112315 Transmission across Chemical Synapses XP_046672578.1 P26308 R-DME-112316 Neuronal System XP_046672578.1 P26308 R-DME-1296041 Activation of G protein gated Potassium channels XP_046672578.1 P26308 R-DME-1296059 G protein gated Potassium channels XP_046672578.1 P26308 R-DME-1296065 Inwardly rectifying K+ channels XP_046672578.1 P26308 R-DME-1296071 Potassium Channels XP_046672578.1 P26308 R-DME-162582 Signal Transduction XP_046672578.1 P26308 R-DME-372790 Signaling by GPCR XP_046672578.1 P26308 R-DME-388396 GPCR downstream signalling XP_046672578.1 P26308 R-DME-390466 Chaperonin-mediated protein folding XP_046672578.1 P26308 R-DME-391251 Protein folding XP_046672578.1 P26308 R-DME-392499 Metabolism of proteins XP_046672578.1 P26308 R-DME-392518 Signal amplification XP_046672578.1 P26308 R-DME-397795 G-protein beta:gamma signalling XP_046672578.1 P26308 R-DME-418594 G alpha (i) signalling events XP_046672578.1 P26308 R-DME-418597 G alpha (z) signalling events XP_046672578.1 P26308 R-DME-428930 Thromboxane signalling through TP receptor XP_046672578.1 P26308 R-DME-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding XP_046672578.1 P26308 R-DME-76002 Platelet activation, signaling and aggregation XP_046672578.1 P26308 R-DME-8964616 G beta:gamma signalling through CDC42 XP_046672578.1 P26308 R-DME-977443 GABA receptor activation XP_046672578.1 P26308 R-DME-977444 GABA B receptor activation XP_046672578.1 P26308 R-DME-991365 Activation of GABAB receptors XP_046672578.1 P26308 R-DME-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits XP_046673103.1 P07487 R-DME-1430728 Metabolism XP_046673103.1 P07487 R-DME-70171 Glycolysis XP_046673103.1 P07487 R-DME-70263 Gluconeogenesis XP_046673103.1 P07487 R-DME-70326 Glucose metabolism XP_046673103.1 P07487 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046674328.1 Q7KUZ5 R-DME-1280218 Adaptive Immune System XP_046674328.1 Q7KUZ5 R-DME-1640170 Cell Cycle XP_046674328.1 Q7KUZ5 R-DME-168256 Immune System XP_046674328.1 Q7KUZ5 R-DME-212436 Generic Transcription Pathway XP_046674328.1 Q7KUZ5 R-DME-3214858 RMTs methylate histone arginines XP_046674328.1 Q7KUZ5 R-DME-3247509 Chromatin modifying enzymes XP_046674328.1 Q7KUZ5 R-DME-388841 Regulation of T cell activation by CD28 family XP_046674328.1 Q7KUZ5 R-DME-389948 Co-inhibition by PD-1 XP_046674328.1 Q7KUZ5 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046674328.1 Q7KUZ5 R-DME-4839726 Chromatin organization XP_046674328.1 Q7KUZ5 R-DME-69231 Cyclin D associated events in G1 XP_046674328.1 Q7KUZ5 R-DME-69236 G1 Phase XP_046674328.1 Q7KUZ5 R-DME-69242 S Phase XP_046674328.1 Q7KUZ5 R-DME-69278 Cell Cycle, Mitotic XP_046674328.1 Q7KUZ5 R-DME-73857 RNA Polymerase II Transcription XP_046674328.1 Q7KUZ5 R-DME-74160 Gene expression (Transcription) XP_046674328.1 Q7KUZ5 R-DME-75815 Ubiquitin-dependent degradation of Cyclin D XP_046674328.1 Q7KUZ5 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046674328.1 Q7KUZ5 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046674328.1 Q7KUZ5 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046674328.1 Q7KUZ5 R-DME-8934593 Regulation of RUNX1 Expression and Activity XP_046674328.1 Q7KUZ5 R-DME-8951936 RUNX3 regulates p14-ARF XP_046674328.1 Q7KUZ5 R-DME-9754119 Drug-mediated inhibition of CDK4/CDK6 activity XP_046674328.1 Q7KUZ5 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046674328.1 Q7KUZ5 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046674328.1 Q7KUZ5 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046658438.1 Q9VXN2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046658438.1 Q9VXN2 R-DME-1430728 Metabolism XP_046658438.1 Q9VXN2 R-DME-1592230 Mitochondrial biogenesis XP_046658438.1 Q9VXN2 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046658438.1 Q9VXN2 R-DME-1852241 Organelle biogenesis and maintenance XP_046658438.1 Q9VXN2 R-DME-8949613 Cristae formation XP_046682560.1 Q9VXN9 R-DME-168249 Innate Immune System XP_046682560.1 Q9VXN9 R-DME-168256 Immune System XP_046682560.1 Q9VXN9 R-DME-209171 Peptidoglycans (PGN) bind to a peptidoglycan recognition protein receptor, PGRP-LC/LE XP_046682560.1 Q9VXN9 R-DME-209266 Peptidoglycan bound PGRP-LC/LE oligomerises XP_046682560.1 Q9VXN9 R-DME-209438 Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046682560.1 Q9VXN9 R-DME-209459 Imd pathway XP_046682560.1 Q9VXN9 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046682560.1 Q9VXN9 R-DME-214397 Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046682560.1 Q9VXN9 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046682560.1 Q9VXN9 R-DME-214411 REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046682560.1 Q9VXN9 R-DME-214416 Phosphorylated REL is cleaved by and dissociates from DREDD XP_046682560.1 Q9VXN9 R-DME-5252538 Drosophila signaling pathways XP_046682560.1 Q9VXN9 R-DME-6798695 Neutrophil degranulation XP_046682560.1 Q9VXN9 R-DME-6803157 Antimicrobial peptides XP_046674055.1 Q9VXI6 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046674055.1 Q9VXI6 R-DME-1430728 Metabolism XP_046674055.1 Q9VXI6 R-DME-611105 Respiratory electron transport XP_046674055.1 Q9VXI6 R-DME-9865881 Complex III assembly XP_046684264.1 Q7YU03 R-DME-1430728 Metabolism XP_046684264.1 Q7YU03 R-DME-1483255 PI Metabolism XP_046684264.1 Q7YU03 R-DME-1483257 Phospholipid metabolism XP_046684264.1 Q7YU03 R-DME-162582 Signal Transduction XP_046684264.1 Q7YU03 R-DME-1632852 Macroautophagy XP_046684264.1 Q7YU03 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046684264.1 Q7YU03 R-DME-1660516 Synthesis of PIPs at the early endosome membrane XP_046684264.1 Q7YU03 R-DME-1660517 Synthesis of PIPs at the late endosome membrane XP_046684264.1 Q7YU03 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046684264.1 Q7YU03 R-DME-2173788 Downregulation of TGF-beta receptor signaling XP_046684264.1 Q7YU03 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046684264.1 Q7YU03 R-DME-556833 Metabolism of lipids XP_046684264.1 Q7YU03 R-DME-9006936 Signaling by TGFB family members XP_046684264.1 Q7YU03 R-DME-9612973 Autophagy XP_046666847.1 Q9VXH3 R-DME-109582 Hemostasis XP_046666847.1 Q9VXH3 R-DME-114604 GPVI-mediated activation cascade XP_046666847.1 Q9VXH3 R-DME-1280218 Adaptive Immune System XP_046666847.1 Q9VXH3 R-DME-1430728 Metabolism XP_046666847.1 Q9VXH3 R-DME-1483249 Inositol phosphate metabolism XP_046666847.1 Q9VXH3 R-DME-162582 Signal Transduction XP_046666847.1 Q9VXH3 R-DME-168249 Innate Immune System XP_046666847.1 Q9VXH3 R-DME-168256 Immune System XP_046666847.1 Q9VXH3 R-DME-177929 Signaling by EGFR XP_046666847.1 Q9VXH3 R-DME-1855204 Synthesis of IP3 and IP4 in the cytosol XP_046666847.1 Q9VXH3 R-DME-186763 Downstream signal transduction XP_046666847.1 Q9VXH3 R-DME-186797 Signaling by PDGF XP_046666847.1 Q9VXH3 R-DME-190236 Signaling by FGFR XP_046666847.1 Q9VXH3 R-DME-202403 TCR signaling XP_046666847.1 Q9VXH3 R-DME-202433 Generation of second messenger molecules XP_046666847.1 Q9VXH3 R-DME-212718 EGFR interacts with phospholipase C-gamma XP_046666847.1 Q9VXH3 R-DME-2172127 DAP12 interactions XP_046666847.1 Q9VXH3 R-DME-2424491 DAP12 signaling XP_046666847.1 Q9VXH3 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046666847.1 Q9VXH3 R-DME-2871796 FCERI mediated MAPK activation XP_046666847.1 Q9VXH3 R-DME-2871809 FCERI mediated Ca+2 mobilization XP_046666847.1 Q9VXH3 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046666847.1 Q9VXH3 R-DME-5621481 C-type lectin receptors (CLRs) XP_046666847.1 Q9VXH3 R-DME-5654219 Phospholipase C-mediated cascade: FGFR1 XP_046666847.1 Q9VXH3 R-DME-5654221 Phospholipase C-mediated cascade; FGFR2 XP_046666847.1 Q9VXH3 R-DME-5654227 Phospholipase C-mediated cascade; FGFR3 XP_046666847.1 Q9VXH3 R-DME-5654228 Phospholipase C-mediated cascade; FGFR4 XP_046666847.1 Q9VXH3 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046666847.1 Q9VXH3 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046666847.1 Q9VXH3 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046666847.1 Q9VXH3 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046666847.1 Q9VXH3 R-DME-5654736 Signaling by FGFR1 XP_046666847.1 Q9VXH3 R-DME-5654738 Signaling by FGFR2 XP_046666847.1 Q9VXH3 R-DME-5654741 Signaling by FGFR3 XP_046666847.1 Q9VXH3 R-DME-5654743 Signaling by FGFR4 XP_046666847.1 Q9VXH3 R-DME-76002 Platelet activation, signaling and aggregation XP_046666847.1 Q9VXH3 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046678774.1 Q0KHR3 R-DME-162582 Signal Transduction XP_046678774.1 Q0KHR3 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046678774.1 Q0KHR3 R-DME-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) XP_046678774.1 Q0KHR3 R-DME-9006936 Signaling by TGFB family members XP_046681409.1 O97111 R-DME-162582 Signal Transduction XP_046681409.1 O97111 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046681409.1 O97111 R-DME-194315 Signaling by Rho GTPases XP_046681409.1 O97111 R-DME-195721 Signaling by WNT XP_046681409.1 O97111 R-DME-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) XP_046681409.1 O97111 R-DME-3858494 Beta-catenin independent WNT signaling XP_046681409.1 O97111 R-DME-4086400 PCP/CE pathway XP_046681409.1 O97111 R-DME-4608870 Asymmetric localization of PCP proteins XP_046681409.1 O97111 R-DME-9006936 Signaling by TGFB family members XP_046681409.1 O97111 R-DME-9012999 RHO GTPase cycle XP_046681409.1 O97111 R-DME-9013149 RAC1 GTPase cycle XP_046681409.1 O97111 R-DME-9013420 RHOU GTPase cycle XP_046681409.1 O97111 R-DME-9013424 RHOV GTPase cycle XP_046681409.1 O97111 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046658326.1 O96525 R-DME-209209 Formation of the activated receptor complex XP_046658326.1 O96525 R-DME-209228 Formation of the activated STAT92E dimer and transport to the nucleus XP_046658326.1 O96525 R-DME-209405 JAK/STAT pathway XP_046658326.1 O96525 R-DME-210688 Dephosphorylation by PTP61F phosphatases XP_046658326.1 O96525 R-DME-5252538 Drosophila signaling pathways XP_046658326.1 Q9VWX2 R-DME-209209 Formation of the activated receptor complex XP_046658326.1 Q9VWX2 R-DME-209228 Formation of the activated STAT92E dimer and transport to the nucleus XP_046658326.1 Q9VWX2 R-DME-209405 JAK/STAT pathway XP_046658326.1 Q9VWX2 R-DME-210688 Dephosphorylation by PTP61F phosphatases XP_046658326.1 Q9VWX2 R-DME-5252538 Drosophila signaling pathways XP_046670997.1 P23647 R-DME-209159 Assembly of the CI containing complexes XP_046670997.1 P23647 R-DME-209190 Phosphorylation of CI XP_046670997.1 P23647 R-DME-209214 Phosphorylation of SMO XP_046670997.1 P23647 R-DME-209338 Assembly of the 'signalling complexes' XP_046670997.1 P23647 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046670997.1 P23647 R-DME-209392 Hedgehog pathway XP_046670997.1 P23647 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046670997.1 P23647 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046670997.1 P23647 R-DME-216119 Activation of CI XP_046670997.1 P23647 R-DME-216217 Activation of SMO XP_046670997.1 P23647 R-DME-5252538 Drosophila signaling pathways XP_046664035.1 Q8MV48 R-DME-392499 Metabolism of proteins XP_046664035.1 Q8MV48 R-DME-5173105 O-linked glycosylation XP_046664035.1 Q8MV48 R-DME-597592 Post-translational protein modification XP_046664035.1 Q8MV48 R-DME-913709 O-linked glycosylation of mucins XP_046665930.1 Q9VWP6 R-DME-109582 Hemostasis XP_046665930.1 Q9VWP6 R-DME-114608 Platelet degranulation XP_046665930.1 Q9VWP6 R-DME-1257604 PIP3 activates AKT signaling XP_046665930.1 Q9VWP6 R-DME-1474244 Extracellular matrix organization XP_046665930.1 Q9VWP6 R-DME-162582 Signal Transduction XP_046665930.1 Q9VWP6 R-DME-186763 Downstream signal transduction XP_046665930.1 Q9VWP6 R-DME-186797 Signaling by PDGF XP_046665930.1 Q9VWP6 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046665930.1 Q9VWP6 R-DME-3000171 Non-integrin membrane-ECM interactions XP_046665930.1 Q9VWP6 R-DME-5673001 RAF/MAP kinase cascade XP_046665930.1 Q9VWP6 R-DME-5683057 MAPK family signaling cascades XP_046665930.1 Q9VWP6 R-DME-5684996 MAPK1/MAPK3 signaling XP_046665930.1 Q9VWP6 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046665930.1 Q9VWP6 R-DME-76002 Platelet activation, signaling and aggregation XP_046665930.1 Q9VWP6 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046665930.1 Q9VWP6 R-DME-9006925 Intracellular signaling by second messengers XP_046665930.1 Q9VWP6 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046669462.1 Q9NHV9 R-DME-109582 Hemostasis XP_046669462.1 Q9NHV9 R-DME-114604 GPVI-mediated activation cascade XP_046669462.1 Q9NHV9 R-DME-1257604 PIP3 activates AKT signaling XP_046669462.1 Q9NHV9 R-DME-1266738 Developmental Biology XP_046669462.1 Q9NHV9 R-DME-1280215 Cytokine Signaling in Immune system XP_046669462.1 Q9NHV9 R-DME-1280218 Adaptive Immune System XP_046669462.1 Q9NHV9 R-DME-1433557 Signaling by SCF-KIT XP_046669462.1 Q9NHV9 R-DME-1500931 Cell-Cell communication XP_046669462.1 Q9NHV9 R-DME-162582 Signal Transduction XP_046669462.1 Q9NHV9 R-DME-168249 Innate Immune System XP_046669462.1 Q9NHV9 R-DME-168256 Immune System XP_046669462.1 Q9NHV9 R-DME-193648 NRAGE signals death through JNK XP_046669462.1 Q9NHV9 R-DME-193704 p75 NTR receptor-mediated signalling XP_046669462.1 Q9NHV9 R-DME-194138 Signaling by VEGF XP_046669462.1 Q9NHV9 R-DME-194315 Signaling by Rho GTPases XP_046669462.1 Q9NHV9 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046669462.1 Q9NHV9 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046669462.1 Q9NHV9 R-DME-2172127 DAP12 interactions XP_046669462.1 Q9NHV9 R-DME-2424491 DAP12 signaling XP_046669462.1 Q9NHV9 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046669462.1 Q9NHV9 R-DME-2682334 EPH-Ephrin signaling XP_046669462.1 Q9NHV9 R-DME-2871796 FCERI mediated MAPK activation XP_046669462.1 Q9NHV9 R-DME-2871809 FCERI mediated Ca+2 mobilization XP_046669462.1 Q9NHV9 R-DME-372790 Signaling by GPCR XP_046669462.1 Q9NHV9 R-DME-373760 L1CAM interactions XP_046669462.1 Q9NHV9 R-DME-388396 GPCR downstream signalling XP_046669462.1 Q9NHV9 R-DME-3928665 EPH-ephrin mediated repulsion of cells XP_046669462.1 Q9NHV9 R-DME-416482 G alpha (12/13) signalling events XP_046669462.1 Q9NHV9 R-DME-418990 Adherens junctions interactions XP_046669462.1 Q9NHV9 R-DME-421270 Cell-cell junction organization XP_046669462.1 Q9NHV9 R-DME-422475 Axon guidance XP_046669462.1 Q9NHV9 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046669462.1 Q9NHV9 R-DME-445144 Signal transduction by L1 XP_046669462.1 Q9NHV9 R-DME-446728 Cell junction organization XP_046669462.1 Q9NHV9 R-DME-449147 Signaling by Interleukins XP_046669462.1 Q9NHV9 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046669462.1 Q9NHV9 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046669462.1 Q9NHV9 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046669462.1 Q9NHV9 R-DME-73887 Death Receptor Signaling XP_046669462.1 Q9NHV9 R-DME-76002 Platelet activation, signaling and aggregation XP_046669462.1 Q9NHV9 R-DME-8980692 RHOA GTPase cycle XP_046669462.1 Q9NHV9 R-DME-9006925 Intracellular signaling by second messengers XP_046669462.1 Q9NHV9 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046669462.1 Q9NHV9 R-DME-9012999 RHO GTPase cycle XP_046669462.1 Q9NHV9 R-DME-9013148 CDC42 GTPase cycle XP_046669462.1 Q9NHV9 R-DME-9013149 RAC1 GTPase cycle XP_046669462.1 Q9NHV9 R-DME-9013423 RAC3 GTPase cycle XP_046669462.1 Q9NHV9 R-DME-912631 Regulation of signaling by CBL XP_046669462.1 Q9NHV9 R-DME-9675108 Nervous system development XP_046669462.1 Q9NHV9 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046669462.1 Q9NHV9 R-DME-9748784 Drug ADME XP_046669462.1 Q9NHV9 R-DME-9748787 Azathioprine ADME XP_046669462.1 Q9NHV9 R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers XP_046669462.1 Q9NHV9 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046669462.1 Q9NHV9 R-DME-9958810 SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) XP_046669462.1 Q9NHV9 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046688516.1 Q9VWJ6 R-DME-1257604 PIP3 activates AKT signaling XP_046688516.1 Q9VWJ6 R-DME-1280218 Adaptive Immune System XP_046688516.1 Q9VWJ6 R-DME-162582 Signal Transduction XP_046688516.1 Q9VWJ6 R-DME-168256 Immune System XP_046688516.1 Q9VWJ6 R-DME-194138 Signaling by VEGF XP_046688516.1 Q9VWJ6 R-DME-388841 Regulation of T cell activation by CD28 family XP_046688516.1 Q9VWJ6 R-DME-389356 Co-stimulation by CD28 XP_046688516.1 Q9VWJ6 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046688516.1 Q9VWJ6 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046688516.1 Q9VWJ6 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046688516.1 Q9VWJ6 R-DME-8953897 Cellular responses to stimuli XP_046688516.1 Q9VWJ6 R-DME-9006925 Intracellular signaling by second messengers XP_046688516.1 Q9VWJ6 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046688516.1 Q9VWJ6 R-DME-9855142 Cellular responses to mechanical stimuli XP_046688516.1 Q9VWJ6 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046688516.1 Q9VWJ6 R-DME-9860931 Response of endothelial cells to shear stress XP_046688046.1 Q9VWK5 R-DME-162582 Signal Transduction XP_046688046.1 Q9VWK5 R-DME-194315 Signaling by Rho GTPases XP_046688046.1 Q9VWK5 R-DME-2990846 SUMOylation XP_046688046.1 Q9VWK5 R-DME-3065679 SUMO is proteolytically processed XP_046688046.1 Q9VWK5 R-DME-3215018 Processing and activation of SUMO XP_046688046.1 Q9VWK5 R-DME-392499 Metabolism of proteins XP_046688046.1 Q9VWK5 R-DME-597592 Post-translational protein modification XP_046688046.1 Q9VWK5 R-DME-6791226 Major pathway of rRNA processing in the nucleolus and cytosol XP_046688046.1 Q9VWK5 R-DME-72312 rRNA processing XP_046688046.1 Q9VWK5 R-DME-8868773 rRNA processing in the nucleus and cytosol XP_046688046.1 Q9VWK5 R-DME-8953854 Metabolism of RNA XP_046688046.1 Q9VWK5 R-DME-9012999 RHO GTPase cycle XP_046688046.1 Q9VWK5 R-DME-9035034 RHOF GTPase cycle XP_046688046.1 Q9VWK5 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046663704.1 Q9VWI0 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046663704.1 Q9VWI0 R-DME-1430728 Metabolism XP_046663704.1 Q9VWI0 R-DME-611105 Respiratory electron transport XP_046663704.1 Q9VWI0 R-DME-6799198 Complex I biogenesis XP_046682297.1 P12646 R-DME-1430728 Metabolism XP_046682297.1 P12646 R-DME-212436 Generic Transcription Pathway XP_046682297.1 P12646 R-DME-3700989 Transcriptional Regulation by TP53 XP_046682297.1 P12646 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046682297.1 P12646 R-DME-71336 Pentose phosphate pathway XP_046682297.1 P12646 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682297.1 P12646 R-DME-73857 RNA Polymerase II Transcription XP_046682297.1 P12646 R-DME-74160 Gene expression (Transcription) XP_046668272.1 P40793 R-DME-109582 Hemostasis XP_046668272.1 P40793 R-DME-114604 GPVI-mediated activation cascade XP_046668272.1 P40793 R-DME-1266738 Developmental Biology XP_046668272.1 P40793 R-DME-1280218 Adaptive Immune System XP_046668272.1 P40793 R-DME-1500931 Cell-Cell communication XP_046668272.1 P40793 R-DME-162582 Signal Transduction XP_046668272.1 P40793 R-DME-168249 Innate Immune System XP_046668272.1 P40793 R-DME-168256 Immune System XP_046668272.1 P40793 R-DME-177929 Signaling by EGFR XP_046668272.1 P40793 R-DME-182971 EGFR downregulation XP_046668272.1 P40793 R-DME-194315 Signaling by Rho GTPases XP_046668272.1 P40793 R-DME-195258 RHO GTPase Effectors XP_046668272.1 P40793 R-DME-2029480 Fcgamma receptor (FCGR) dependent phagocytosis XP_046668272.1 P40793 R-DME-2029482 Regulation of actin dynamics for phagocytic cup formation XP_046668272.1 P40793 R-DME-2682334 EPH-Ephrin signaling XP_046668272.1 P40793 R-DME-372790 Signaling by GPCR XP_046668272.1 P40793 R-DME-388396 GPCR downstream signalling XP_046668272.1 P40793 R-DME-388841 Regulation of T cell activation by CD28 family XP_046668272.1 P40793 R-DME-389356 Co-stimulation by CD28 XP_046668272.1 P40793 R-DME-389359 CD28 dependent Vav1 pathway XP_046668272.1 P40793 R-DME-3928662 EPHB-mediated forward signaling XP_046668272.1 P40793 R-DME-397795 G-protein beta:gamma signalling XP_046668272.1 P40793 R-DME-418990 Adherens junctions interactions XP_046668272.1 P40793 R-DME-421270 Cell-cell junction organization XP_046668272.1 P40793 R-DME-422475 Axon guidance XP_046668272.1 P40793 R-DME-446728 Cell junction organization XP_046668272.1 P40793 R-DME-525793 Myogenesis XP_046668272.1 P40793 R-DME-5627123 RHO GTPases activate PAKs XP_046668272.1 P40793 R-DME-5663213 RHO GTPases Activate WASPs and WAVEs XP_046668272.1 P40793 R-DME-5663220 RHO GTPases Activate Formins XP_046668272.1 P40793 R-DME-5683057 MAPK family signaling cascades XP_046668272.1 P40793 R-DME-5687128 MAPK6/MAPK4 signaling XP_046668272.1 P40793 R-DME-76002 Platelet activation, signaling and aggregation XP_046668272.1 P40793 R-DME-8964616 G beta:gamma signalling through CDC42 XP_046668272.1 P40793 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046668272.1 P40793 R-DME-9012999 RHO GTPase cycle XP_046668272.1 P40793 R-DME-9013148 CDC42 GTPase cycle XP_046668272.1 P40793 R-DME-9013149 RAC1 GTPase cycle XP_046668272.1 P40793 R-DME-9013406 RHOQ GTPase cycle XP_046668272.1 P40793 R-DME-9013409 RHOJ GTPase cycle XP_046668272.1 P40793 R-DME-9013420 RHOU GTPase cycle XP_046668272.1 P40793 R-DME-9013423 RAC3 GTPase cycle XP_046668272.1 P40793 R-DME-9013424 RHOV GTPase cycle XP_046668272.1 P40793 R-DME-9675108 Nervous system development XP_046668272.1 P40793 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046668272.1 P40793 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046668272.1 P40793 R-DME-9958810 SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) XP_046668272.1 P40793 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046682111.1 Q9VWE0 R-DME-168249 Innate Immune System XP_046682111.1 Q9VWE0 R-DME-168256 Immune System XP_046682111.1 Q9VWE0 R-DME-209209 Formation of the activated receptor complex XP_046682111.1 Q9VWE0 R-DME-209228 Formation of the activated STAT92E dimer and transport to the nucleus XP_046682111.1 Q9VWE0 R-DME-209405 JAK/STAT pathway XP_046682111.1 Q9VWE0 R-DME-210688 Dephosphorylation by PTP61F phosphatases XP_046682111.1 Q9VWE0 R-DME-5252538 Drosophila signaling pathways XP_046682111.1 Q9VWE0 R-DME-6798695 Neutrophil degranulation XP_046677679.1 Q9VWH4 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046677679.1 Q9VWH4 R-DME-1430728 Metabolism XP_046677679.1 Q9VWH4 R-DME-392499 Metabolism of proteins XP_046677679.1 Q9VWH4 R-DME-71403 Citric acid cycle (TCA cycle) XP_046677679.1 Q9VWH4 R-DME-9837999 Mitochondrial protein degradation XP_046659534.1 Q9VWD1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659534.1 Q9VWD1 R-DME-1430728 Metabolism XP_046659534.1 Q9VWD1 R-DME-212436 Generic Transcription Pathway XP_046659534.1 Q9VWD1 R-DME-2262752 Cellular responses to stress XP_046659534.1 Q9VWD1 R-DME-3700989 Transcriptional Regulation by TP53 XP_046659534.1 Q9VWD1 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046659534.1 Q9VWD1 R-DME-611105 Respiratory electron transport XP_046659534.1 Q9VWD1 R-DME-73857 RNA Polymerase II Transcription XP_046659534.1 Q9VWD1 R-DME-74160 Gene expression (Transcription) XP_046659534.1 Q9VWD1 R-DME-8953897 Cellular responses to stimuli XP_046659534.1 Q9VWD1 R-DME-9707564 Cytoprotection by HMOX1 XP_046659534.1 Q9VWD1 R-DME-9711123 Cellular response to chemical stress XP_046659534.1 Q9VWD1 R-DME-9864848 Complex IV assembly XP_046660620.1 Q9U9B0 R-DME-110523 TOR signaling pathway XP_046660620.1 Q9U9B0 R-DME-110526 Insulin receptor mediated signaling XP_046660620.1 Q9U9B0 R-DME-5252538 Drosophila signaling pathways XP_046660620.1 Q9VW83 R-DME-1257604 PIP3 activates AKT signaling XP_046660620.1 Q9VW83 R-DME-162582 Signal Transduction XP_046660620.1 Q9VW83 R-DME-1632852 Macroautophagy XP_046660620.1 Q9VW83 R-DME-165159 MTOR signalling XP_046660620.1 Q9VW83 R-DME-165181 Inhibition of TSC complex formation by AKT (PKB) XP_046660620.1 Q9VW83 R-DME-198323 AKT phosphorylates targets in the cytosol XP_046660620.1 Q9VW83 R-DME-199991 Membrane Trafficking XP_046660620.1 Q9VW83 R-DME-212436 Generic Transcription Pathway XP_046660620.1 Q9VW83 R-DME-3700989 Transcriptional Regulation by TP53 XP_046660620.1 Q9VW83 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046660620.1 Q9VW83 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046660620.1 Q9VW83 R-DME-5653656 Vesicle-mediated transport XP_046660620.1 Q9VW83 R-DME-73857 RNA Polymerase II Transcription XP_046660620.1 Q9VW83 R-DME-74160 Gene expression (Transcription) XP_046660620.1 Q9VW83 R-DME-8854214 TBC/RABGAPs XP_046660620.1 Q9VW83 R-DME-9006925 Intracellular signaling by second messengers XP_046660620.1 Q9VW83 R-DME-9007101 Rab regulation of trafficking XP_046660620.1 Q9VW83 R-DME-9612973 Autophagy XP_046669087.1 Q9VW47 R-DME-212165 Epigenetic regulation of gene expression XP_046669087.1 Q9VW47 R-DME-74160 Gene expression (Transcription) XP_046669087.1 Q9VW47 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046669087.1 Q9VW47 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046669087.1 Q9VW47 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046669087.1 Q9VW47 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046665064.1 Q8IQV1 R-DME-1430728 Metabolism XP_046665064.1 Q8IQV1 R-DME-1630316 Glycosaminoglycan metabolism XP_046665064.1 Q8IQV1 R-DME-174362 Transport and metabolism of PAPS XP_046665064.1 Q8IQV1 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046660825.1 Q8IQV0 R-DME-392499 Metabolism of proteins XP_046660825.1 Q8IQV0 R-DME-4085001 Sialic acid metabolism XP_046660825.1 Q8IQV0 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046660825.1 Q8IQV0 R-DME-446203 Asparagine N-linked glycosylation XP_046660825.1 Q8IQV0 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046660825.1 Q8IQV0 R-DME-597592 Post-translational protein modification XP_046670451.1 P29829 R-DME-109582 Hemostasis XP_046670451.1 P29829 R-DME-112314 Neurotransmitter receptors and postsynaptic signal transmission XP_046670451.1 P29829 R-DME-112315 Transmission across Chemical Synapses XP_046670451.1 P29829 R-DME-112316 Neuronal System XP_046670451.1 P29829 R-DME-1296041 Activation of G protein gated Potassium channels XP_046670451.1 P29829 R-DME-1296059 G protein gated Potassium channels XP_046670451.1 P29829 R-DME-1296065 Inwardly rectifying K+ channels XP_046670451.1 P29829 R-DME-1296071 Potassium Channels XP_046670451.1 P29829 R-DME-162582 Signal Transduction XP_046670451.1 P29829 R-DME-372790 Signaling by GPCR XP_046670451.1 P29829 R-DME-388396 GPCR downstream signalling XP_046670451.1 P29829 R-DME-390466 Chaperonin-mediated protein folding XP_046670451.1 P29829 R-DME-391251 Protein folding XP_046670451.1 P29829 R-DME-392499 Metabolism of proteins XP_046670451.1 P29829 R-DME-392518 Signal amplification XP_046670451.1 P29829 R-DME-397795 G-protein beta:gamma signalling XP_046670451.1 P29829 R-DME-418594 G alpha (i) signalling events XP_046670451.1 P29829 R-DME-418597 G alpha (z) signalling events XP_046670451.1 P29829 R-DME-428930 Thromboxane signalling through TP receptor XP_046670451.1 P29829 R-DME-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding XP_046670451.1 P29829 R-DME-76002 Platelet activation, signaling and aggregation XP_046670451.1 P29829 R-DME-8964616 G beta:gamma signalling through CDC42 XP_046670451.1 P29829 R-DME-977443 GABA receptor activation XP_046670451.1 P29829 R-DME-977444 GABA B receptor activation XP_046670451.1 P29829 R-DME-991365 Activation of GABAB receptors XP_046670451.1 P29829 R-DME-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits XP_046660315.1 B7Z078 R-DME-1257604 PIP3 activates AKT signaling XP_046660315.1 B7Z078 R-DME-162582 Signal Transduction XP_046660315.1 B7Z078 R-DME-195721 Signaling by WNT XP_046660315.1 B7Z078 R-DME-201681 TCF dependent signaling in response to WNT XP_046660315.1 B7Z078 R-DME-4641257 Degradation of AXIN XP_046660315.1 B7Z078 R-DME-6807070 PTEN Regulation XP_046660315.1 B7Z078 R-DME-8948751 Regulation of PTEN stability and activity XP_046660315.1 B7Z078 R-DME-9006925 Intracellular signaling by second messengers XP_046659751.1 Q86BJ3 R-DME-1430728 Metabolism XP_046659751.1 Q86BJ3 R-DME-1630316 Glycosaminoglycan metabolism XP_046659751.1 Q86BJ3 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046659751.1 Q86BJ3 R-DME-2022870 CS-GAG biosynthesis XP_046659751.1 Q86BJ3 R-DME-2022923 DS-GAG biosynthesis XP_046659751.1 Q86BJ3 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046659572.1 Q9VVX3 R-DME-162582 Signal Transduction XP_046659572.1 Q9VVX3 R-DME-195721 Signaling by WNT XP_046659572.1 Q9VVX3 R-DME-209387 Phosphorylation of ARR XP_046659572.1 Q9VVX3 R-DME-209412 Wingless pathway XP_046659572.1 Q9VVX3 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046659572.1 Q9VVX3 R-DME-209469 WG ligand bound to FZ receptors XP_046659572.1 Q9VVX3 R-DME-209472 Assembly of receptor complex XP_046659572.1 Q9VVX3 R-DME-3858494 Beta-catenin independent WNT signaling XP_046659572.1 Q9VVX3 R-DME-4086400 PCP/CE pathway XP_046659572.1 Q9VVX3 R-DME-4608870 Asymmetric localization of PCP proteins XP_046659572.1 Q9VVX3 R-DME-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 XP_046659572.1 Q9VVX3 R-DME-5252538 Drosophila signaling pathways XP_046682184.1 Q9VVM6 R-DME-1430728 Metabolism XP_046682184.1 Q9VVM6 R-DME-1630316 Glycosaminoglycan metabolism XP_046682184.1 Q9VVM6 R-DME-174362 Transport and metabolism of PAPS XP_046682184.1 Q9VVM6 R-DME-382551 Transport of small molecules XP_046682184.1 Q9VVM6 R-DME-425407 SLC-mediated transmembrane transport XP_046682184.1 Q9VVM6 R-DME-427601 Inorganic anion exchange by SLC26 transporters XP_046682184.1 Q9VVM6 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682184.1 Q9VVM6 R-DME-9958790 SLC-mediated transport of inorganic anions XP_046674207.1 Q9VVH5 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046674207.1 Q9VVH5 R-DME-1430728 Metabolism XP_046674207.1 Q9VVH5 R-DME-392499 Metabolism of proteins XP_046674207.1 Q9VVH5 R-DME-611105 Respiratory electron transport XP_046674207.1 Q9VVH5 R-DME-9837999 Mitochondrial protein degradation XP_046674207.1 Q9VVH5 R-DME-9865881 Complex III assembly XP_046686888.1 Q9VVG6 R-DME-1430728 Metabolism XP_046686888.1 Q9VVG6 R-DME-196854 Metabolism of vitamins and cofactors XP_046686888.1 Q9VVG6 R-DME-2142789 Ubiquinol biosynthesis XP_046686888.1 Q9VVG6 R-DME-8978934 Metabolism of cofactors XP_046669650.1 Q95YI5 R-DME-1430728 Metabolism XP_046669650.1 Q95YI5 R-DME-156580 Phase II - Conjugation of compounds XP_046669650.1 Q95YI5 R-DME-156588 Glucuronidation XP_046669650.1 Q95YI5 R-DME-1630316 Glycosaminoglycan metabolism XP_046669650.1 Q95YI5 R-DME-1638074 Keratan sulfate/keratin metabolism XP_046669650.1 Q95YI5 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046669650.1 Q95YI5 R-DME-173599 Formation of the active cofactor, UDP-glucuronate XP_046669650.1 Q95YI5 R-DME-2022854 Keratan sulfate biosynthesis XP_046669650.1 Q95YI5 R-DME-2022928 HS-GAG biosynthesis XP_046669650.1 Q95YI5 R-DME-211859 Biological oxidations XP_046669650.1 Q95YI5 R-DME-382551 Transport of small molecules XP_046669650.1 Q95YI5 R-DME-425397 Transport of vitamins, nucleosides, and related molecules XP_046669650.1 Q95YI5 R-DME-425407 SLC-mediated transmembrane transport XP_046669650.1 Q95YI5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046669650.1 Q95YI5 R-DME-727802 Transport of nucleotide sugars XP_046664713.1 A8JNU6 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046664713.1 A8JNU6 R-DME-1430728 Metabolism XP_046664713.1 A8JNU6 R-DME-389661 Glyoxylate metabolism and glycine degradation XP_046664713.1 A8JNU6 R-DME-392499 Metabolism of proteins XP_046664713.1 A8JNU6 R-DME-6783984 Glycine degradation XP_046664713.1 A8JNU6 R-DME-71291 Metabolism of amino acids and derivatives XP_046664713.1 A8JNU6 R-DME-71403 Citric acid cycle (TCA cycle) XP_046664713.1 A8JNU6 R-DME-9837999 Mitochondrial protein degradation XP_046664713.1 A8JNU6 R-DME-9853506 OGDH complex synthesizes succinyl-CoA from 2-OG XP_046687140.1 Q9VVD9 R-DME-1430728 Metabolism XP_046687140.1 Q9VVD9 R-DME-1630316 Glycosaminoglycan metabolism XP_046687140.1 Q9VVD9 R-DME-174362 Transport and metabolism of PAPS XP_046687140.1 Q9VVD9 R-DME-382551 Transport of small molecules XP_046687140.1 Q9VVD9 R-DME-425397 Transport of vitamins, nucleosides, and related molecules XP_046687140.1 Q9VVD9 R-DME-425407 SLC-mediated transmembrane transport XP_046687140.1 Q9VVD9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046687140.1 Q9VVD9 R-DME-727802 Transport of nucleotide sugars XP_046683983.1 P21461 R-DME-1280218 Adaptive Immune System XP_046683983.1 P21461 R-DME-168256 Immune System XP_046683983.1 P21461 R-DME-392499 Metabolism of proteins XP_046683983.1 P21461 R-DME-5688426 Deubiquitination XP_046683983.1 P21461 R-DME-5689880 Ub-specific processing proteases XP_046683983.1 P21461 R-DME-597592 Post-translational protein modification XP_046683983.1 P21461 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046683983.1 P21461 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046671188.1 Q9VUX3 R-DME-162582 Signal Transduction XP_046671188.1 Q9VUX3 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046671188.1 Q9VUX3 R-DME-392499 Metabolism of proteins XP_046671188.1 Q9VUX3 R-DME-5358346 Hedgehog ligand biogenesis XP_046671188.1 Q9VUX3 R-DME-5358351 Signaling by Hedgehog XP_046671188.1 Q9VUX3 R-DME-5362798 Release of Hh-Np from the secreting cell XP_046671188.1 Q9VUX3 R-DME-597592 Post-translational protein modification XP_046671188.1 Q9VUX3 R-DME-8957275 Post-translational protein phosphorylation XP_046666640.1 Q9VUY9 R-DME-1430728 Metabolism XP_046666640.1 Q9VUY9 R-DME-168249 Innate Immune System XP_046666640.1 Q9VUY9 R-DME-168256 Immune System XP_046666640.1 Q9VUY9 R-DME-3322077 Glycogen synthesis XP_046666640.1 Q9VUY9 R-DME-6798695 Neutrophil degranulation XP_046666640.1 Q9VUY9 R-DME-70221 Glycogen breakdown (glycogenolysis) XP_046666640.1 Q9VUY9 R-DME-70370 Galactose catabolism XP_046666640.1 Q9VUY9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046666640.1 Q9VUY9 R-DME-8982491 Glycogen metabolism XP_046677230.1 Q95TS5 R-DME-6807505 RNA polymerase II transcribes snRNA genes XP_046677230.1 Q95TS5 R-DME-73857 RNA Polymerase II Transcription XP_046677230.1 Q95TS5 R-DME-74160 Gene expression (Transcription) XP_046665614.1 Q9VUT6 R-DME-392499 Metabolism of proteins XP_046665614.1 Q9VUT6 R-DME-5173105 O-linked glycosylation XP_046665614.1 Q9VUT6 R-DME-597592 Post-translational protein modification XP_046665614.1 Q9VUT6 R-DME-913709 O-linked glycosylation of mucins XP_046669601.1 Q9VUL9 R-DME-1430728 Metabolism XP_046669601.1 Q9VUL9 R-DME-392499 Metabolism of proteins XP_046669601.1 Q9VUL9 R-DME-446203 Asparagine N-linked glycosylation XP_046669601.1 Q9VUL9 R-DME-597592 Post-translational protein modification XP_046669601.1 Q9VUL9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046669601.1 Q9VUL9 R-DME-9033658 Blood group systems biosynthesis XP_046669601.1 Q9VUL9 R-DME-9037629 Lewis blood group biosynthesis XP_046669601.1 Q9VUL9 R-DME-948021 Transport to the Golgi and subsequent modification XP_046669601.1 Q9VUL9 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046669601.1 Q9VUL9 R-DME-975578 Reactions specific to the complex N-glycan synthesis pathway XP_046676795.1 P18537 R-DME-162582 Signal Transduction XP_046676795.1 P18537 R-DME-195721 Signaling by WNT XP_046676795.1 P18537 R-DME-201681 TCF dependent signaling in response to WNT XP_046676795.1 P18537 R-DME-209387 Phosphorylation of ARR XP_046676795.1 P18537 R-DME-209412 Wingless pathway XP_046676795.1 P18537 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046676795.1 P18537 R-DME-209469 WG ligand bound to FZ receptors XP_046676795.1 P18537 R-DME-209472 Assembly of receptor complex XP_046676795.1 P18537 R-DME-350368 Activation of RHO1 by FZ:DSH complex XP_046676795.1 P18537 R-DME-350376 Activation of RAC1:GTP by FZ:DSH complex XP_046676795.1 P18537 R-DME-350379 Homo-/heterophilic binding of transmembrane components XP_046676795.1 P18537 R-DME-350411 Formation and asymmetric localisation of transmembrane complexes XP_046676795.1 P18537 R-DME-350431 Planar Cell Polarity pathway XP_046676795.1 P18537 R-DME-350480 Activation of non-muscle Myosin II XP_046676795.1 P18537 R-DME-3858494 Beta-catenin independent WNT signaling XP_046676795.1 P18537 R-DME-4086400 PCP/CE pathway XP_046676795.1 P18537 R-DME-450728 Inhibition of actin polymerization XP_046676795.1 P18537 R-DME-450736 Activation of Downstream Effectors XP_046676795.1 P18537 R-DME-450799 RHO1 signalling XP_046676795.1 P18537 R-DME-4608870 Asymmetric localization of PCP proteins XP_046676795.1 P18537 R-DME-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane XP_046676795.1 P18537 R-DME-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 XP_046676795.1 P18537 R-DME-5252538 Drosophila signaling pathways XP_046676300.1 M9PCE9 R-DME-162582 Signal Transduction XP_046676300.1 M9PCE9 R-DME-166520 Signaling by NTRKs XP_046676300.1 M9PCE9 R-DME-167044 Signalling to RAS XP_046676300.1 M9PCE9 R-DME-171007 p38MAPK events XP_046676300.1 M9PCE9 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046676300.1 M9PCE9 R-DME-187687 Signalling to ERKs XP_046676300.1 M9PCE9 R-DME-5673001 RAF/MAP kinase cascade XP_046676300.1 M9PCE9 R-DME-5683057 MAPK family signaling cascades XP_046676300.1 M9PCE9 R-DME-5684996 MAPK1/MAPK3 signaling XP_046676300.1 M9PCE9 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046662958.1 Q9VTZ6 R-DME-392499 Metabolism of proteins XP_046662958.1 Q9VTZ6 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046662958.1 Q9VTZ6 R-DME-446203 Asparagine N-linked glycosylation XP_046662958.1 Q9VTZ6 R-DME-446205 Synthesis of GDP-mannose XP_046662958.1 Q9VTZ6 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046662958.1 Q9VTZ6 R-DME-597592 Post-translational protein modification XP_046667102.1 Q9VTZ4 R-DME-392499 Metabolism of proteins XP_046667102.1 Q9VTZ4 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046667102.1 Q9VTZ4 R-DME-446203 Asparagine N-linked glycosylation XP_046667102.1 Q9VTZ4 R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine XP_046667102.1 Q9VTZ4 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046667102.1 Q9VTZ4 R-DME-597592 Post-translational protein modification XP_046686990.1 Q9VTV9 R-DME-1430728 Metabolism XP_046686990.1 Q9VTV9 R-DME-168249 Innate Immune System XP_046686990.1 Q9VTV9 R-DME-168256 Immune System XP_046686990.1 Q9VTV9 R-DME-189445 Metabolism of porphyrins XP_046686990.1 Q9VTV9 R-DME-189451 Heme biosynthesis XP_046686990.1 Q9VTV9 R-DME-6798695 Neutrophil degranulation XP_046674354.1 Q9VTU2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046674354.1 Q9VTU2 R-DME-1430728 Metabolism XP_046674354.1 Q9VTU2 R-DME-611105 Respiratory electron transport XP_046674354.1 Q9VTU2 R-DME-6799198 Complex I biogenesis XP_046666301.1 Q7K3H0 R-DME-1430728 Metabolism XP_046666301.1 Q7K3H0 R-DME-1483255 PI Metabolism XP_046666301.1 Q7K3H0 R-DME-1483257 Phospholipid metabolism XP_046666301.1 Q7K3H0 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046666301.1 Q7K3H0 R-DME-1660514 Synthesis of PIPs at the Golgi membrane XP_046666301.1 Q7K3H0 R-DME-1660516 Synthesis of PIPs at the early endosome membrane XP_046666301.1 Q7K3H0 R-DME-1660517 Synthesis of PIPs at the late endosome membrane XP_046666301.1 Q7K3H0 R-DME-199991 Membrane Trafficking XP_046666301.1 Q7K3H0 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046666301.1 Q7K3H0 R-DME-432722 Golgi Associated Vesicle Biogenesis XP_046666301.1 Q7K3H0 R-DME-556833 Metabolism of lipids XP_046666301.1 Q7K3H0 R-DME-5653656 Vesicle-mediated transport XP_046666301.1 Q7K3H0 R-DME-8856828 Clathrin-mediated endocytosis XP_046676780.1 Q9VTK2 R-DME-392499 Metabolism of proteins XP_046676780.1 Q9VTK2 R-DME-5173105 O-linked glycosylation XP_046676780.1 Q9VTK2 R-DME-597592 Post-translational protein modification XP_046676780.1 Q9VTK2 R-DME-8931838 DAG1 glycosylations XP_046676780.1 Q9VTK2 R-DME-8932504 DAG1 core M2 glycosylations XP_046676780.1 Q9VTK2 R-DME-8932505 DAG1 core M3 glycosylations XP_046676780.1 Q9VTK2 R-DME-8932506 DAG1 core M1 glycosylations XP_046684571.1 Q9VTH1 R-DME-1280218 Adaptive Immune System XP_046684571.1 Q9VTH1 R-DME-168256 Immune System XP_046684571.1 Q9VTH1 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046684571.1 Q9VTH1 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046688155.1 Q9VTH0 R-DME-1474244 Extracellular matrix organization XP_046688155.1 Q9VTH0 R-DME-1474290 Collagen formation XP_046688155.1 Q9VTH0 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046683981.1 Q95ST2 R-DME-162582 Signal Transduction XP_046683981.1 Q95ST2 R-DME-195721 Signaling by WNT XP_046683981.1 Q95ST2 R-DME-3238698 WNT ligand biogenesis and trafficking XP_046661330.1 Q9VTF9 R-DME-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template XP_046661330.1 Q9VTF9 R-DME-110320 Translesion Synthesis by POLH XP_046661330.1 Q9VTF9 R-DME-2262752 Cellular responses to stress XP_046661330.1 Q9VTF9 R-DME-392499 Metabolism of proteins XP_046661330.1 Q9VTF9 R-DME-5688426 Deubiquitination XP_046661330.1 Q9VTF9 R-DME-5689880 Ub-specific processing proteases XP_046661330.1 Q9VTF9 R-DME-597592 Post-translational protein modification XP_046661330.1 Q9VTF9 R-DME-73893 DNA Damage Bypass XP_046661330.1 Q9VTF9 R-DME-73894 DNA Repair XP_046661330.1 Q9VTF9 R-DME-8951664 Neddylation XP_046661330.1 Q9VTF9 R-DME-8953897 Cellular responses to stimuli XP_046661330.1 Q9VTF9 R-DME-9711123 Cellular response to chemical stress XP_046661330.1 Q9VTF9 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046662175.1 Q9VTB4 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046662175.1 Q9VTB4 R-DME-1430728 Metabolism XP_046662175.1 Q9VTB4 R-DME-611105 Respiratory electron transport XP_046662175.1 Q9VTB4 R-DME-6799198 Complex I biogenesis XP_046668933.1 P48423 R-DME-162582 Signal Transduction XP_046668933.1 P48423 R-DME-5658442 Regulation of RAS by GAPs XP_046668933.1 P48423 R-DME-5673001 RAF/MAP kinase cascade XP_046668933.1 P48423 R-DME-5683057 MAPK family signaling cascades XP_046668933.1 P48423 R-DME-5684996 MAPK1/MAPK3 signaling XP_046666291.1 Q9VT52 R-DME-110478 Insulin signaling pathway XP_046666291.1 Q9VT52 R-DME-110526 Insulin receptor mediated signaling XP_046666291.1 Q9VT52 R-DME-5252538 Drosophila signaling pathways XP_046663718.1 P52486 R-DME-1280218 Adaptive Immune System XP_046663718.1 P52486 R-DME-168256 Immune System XP_046663718.1 P52486 R-DME-392499 Metabolism of proteins XP_046663718.1 P52486 R-DME-597592 Post-translational protein modification XP_046663718.1 P52486 R-DME-8852135 Protein ubiquitination XP_046663718.1 P52486 R-DME-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes XP_046663718.1 P52486 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046663718.1 P52486 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046683685.1 Q9NCC3 R-DME-199991 Membrane Trafficking XP_046683685.1 Q9NCC3 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046683685.1 Q9NCC3 R-DME-432722 Golgi Associated Vesicle Biogenesis XP_046683685.1 Q9NCC3 R-DME-5653656 Vesicle-mediated transport XP_046683685.1 Q9NCC3 R-DME-8856828 Clathrin-mediated endocytosis XP_046682560.1 Q8SXQ7 R-DME-168249 Innate Immune System XP_046682560.1 Q8SXQ7 R-DME-168256 Immune System XP_046682560.1 Q8SXQ7 R-DME-6798695 Neutrophil degranulation XP_046682560.1 Q8SXQ7 R-DME-6803157 Antimicrobial peptides XP_046661331.1 Q9V3C8 R-DME-109582 Hemostasis XP_046661331.1 Q9V3C8 R-DME-1227986 Signaling by ERBB2 XP_046661331.1 Q9V3C8 R-DME-1236394 Signaling by ERBB4 XP_046661331.1 Q9V3C8 R-DME-1250196 SHC1 events in ERBB2 signaling XP_046661331.1 Q9V3C8 R-DME-1250347 SHC1 events in ERBB4 signaling XP_046661331.1 Q9V3C8 R-DME-1266738 Developmental Biology XP_046661331.1 Q9V3C8 R-DME-162582 Signal Transduction XP_046661331.1 Q9V3C8 R-DME-166520 Signaling by NTRKs XP_046661331.1 Q9V3C8 R-DME-167044 Signalling to RAS XP_046661331.1 Q9V3C8 R-DME-168249 Innate Immune System XP_046661331.1 Q9V3C8 R-DME-168256 Immune System XP_046661331.1 Q9V3C8 R-DME-177929 Signaling by EGFR XP_046661331.1 Q9V3C8 R-DME-180336 SHC1 events in EGFR signaling XP_046661331.1 Q9V3C8 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046661331.1 Q9V3C8 R-DME-187687 Signalling to ERKs XP_046661331.1 Q9V3C8 R-DME-190236 Signaling by FGFR XP_046661331.1 Q9V3C8 R-DME-202733 Cell surface interactions at the vascular wall XP_046661331.1 Q9V3C8 R-DME-210993 Tie2 Signaling XP_046661331.1 Q9V3C8 R-DME-2172127 DAP12 interactions XP_046661331.1 Q9V3C8 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046661331.1 Q9V3C8 R-DME-2424491 DAP12 signaling XP_046661331.1 Q9V3C8 R-DME-2428924 IGF1R signaling cascade XP_046661331.1 Q9V3C8 R-DME-2428933 SHC-related events triggered by IGF1R XP_046661331.1 Q9V3C8 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046661331.1 Q9V3C8 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046661331.1 Q9V3C8 R-DME-2871796 FCERI mediated MAPK activation XP_046661331.1 Q9V3C8 R-DME-2871809 FCERI mediated Ca+2 mobilization XP_046661331.1 Q9V3C8 R-DME-354192 Integrin signaling XP_046661331.1 Q9V3C8 R-DME-422475 Axon guidance XP_046661331.1 Q9V3C8 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046661331.1 Q9V3C8 R-DME-5654688 SHC-mediated cascade:FGFR1 XP_046661331.1 Q9V3C8 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046661331.1 Q9V3C8 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046661331.1 Q9V3C8 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046661331.1 Q9V3C8 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046661331.1 Q9V3C8 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046661331.1 Q9V3C8 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046661331.1 Q9V3C8 R-DME-5654736 Signaling by FGFR1 XP_046661331.1 Q9V3C8 R-DME-5654738 Signaling by FGFR2 XP_046661331.1 Q9V3C8 R-DME-5654741 Signaling by FGFR3 XP_046661331.1 Q9V3C8 R-DME-5654743 Signaling by FGFR4 XP_046661331.1 Q9V3C8 R-DME-5673001 RAF/MAP kinase cascade XP_046661331.1 Q9V3C8 R-DME-5683057 MAPK family signaling cascades XP_046661331.1 Q9V3C8 R-DME-5684996 MAPK1/MAPK3 signaling XP_046661331.1 Q9V3C8 R-DME-74749 Signal attenuation XP_046661331.1 Q9V3C8 R-DME-74751 Insulin receptor signalling cascade XP_046661331.1 Q9V3C8 R-DME-74752 Signaling by Insulin receptor XP_046661331.1 Q9V3C8 R-DME-76002 Platelet activation, signaling and aggregation XP_046661331.1 Q9V3C8 R-DME-76009 Platelet Aggregation (Plug Formation) XP_046661331.1 Q9V3C8 R-DME-8853659 RET signaling XP_046661331.1 Q9V3C8 R-DME-8939211 ESR-mediated signaling XP_046661331.1 Q9V3C8 R-DME-9006931 Signaling by Nuclear Receptors XP_046661331.1 Q9V3C8 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046661331.1 Q9V3C8 R-DME-9009391 Extra-nuclear estrogen signaling XP_046661331.1 Q9V3C8 R-DME-9675108 Nervous system development XP_046678404.1 Q9XZ61 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046678404.1 Q9XZ61 R-DME-209392 Hedgehog pathway XP_046678404.1 Q9XZ61 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046678404.1 Q9XZ61 R-DME-209412 Wingless pathway XP_046678404.1 Q9XZ61 R-DME-209441 WG ligand not bound to FZ receptors XP_046678404.1 Q9XZ61 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046678404.1 Q9XZ61 R-DME-209449 Toll pathway XP_046678404.1 Q9XZ61 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046678404.1 Q9XZ61 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046678404.1 Q9XZ61 R-DME-216167 Nuclear CI is degraded XP_046678404.1 Q9XZ61 R-DME-392499 Metabolism of proteins XP_046678404.1 Q9XZ61 R-DME-432395 Degradation of TIM XP_046678404.1 Q9XZ61 R-DME-432524 Degradation of PER XP_046678404.1 Q9XZ61 R-DME-432626 Circadian Clock pathway XP_046678404.1 Q9XZ61 R-DME-5252538 Drosophila signaling pathways XP_046678404.1 Q9XZ61 R-DME-538864 Degradation of CRY XP_046678404.1 Q9XZ61 R-DME-5688426 Deubiquitination XP_046678404.1 Q9XZ61 R-DME-5689603 UCH proteinases XP_046678404.1 Q9XZ61 R-DME-597592 Post-translational protein modification XP_046678913.1 P37193 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046678913.1 P37193 R-DME-1430728 Metabolism XP_046678913.1 P37193 R-DME-2395516 Electron transport from NADPH to Ferredoxin XP_046677339.1 Q9VSK2 R-DME-1280215 Cytokine Signaling in Immune system XP_046677339.1 Q9VSK2 R-DME-1280218 Adaptive Immune System XP_046677339.1 Q9VSK2 R-DME-1295596 Spry regulation of FGF signaling XP_046677339.1 Q9VSK2 R-DME-1433557 Signaling by SCF-KIT XP_046677339.1 Q9VSK2 R-DME-1433559 Regulation of KIT signaling XP_046677339.1 Q9VSK2 R-DME-162582 Signal Transduction XP_046677339.1 Q9VSK2 R-DME-168256 Immune System XP_046677339.1 Q9VSK2 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046677339.1 Q9VSK2 R-DME-177929 Signaling by EGFR XP_046677339.1 Q9VSK2 R-DME-182971 EGFR downregulation XP_046677339.1 Q9VSK2 R-DME-190236 Signaling by FGFR XP_046677339.1 Q9VSK2 R-DME-199991 Membrane Trafficking XP_046677339.1 Q9VSK2 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046677339.1 Q9VSK2 R-DME-449147 Signaling by Interleukins XP_046677339.1 Q9VSK2 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046677339.1 Q9VSK2 R-DME-5653656 Vesicle-mediated transport XP_046677339.1 Q9VSK2 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046677339.1 Q9VSK2 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046677339.1 Q9VSK2 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046677339.1 Q9VSK2 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046677339.1 Q9VSK2 R-DME-5654736 Signaling by FGFR1 XP_046677339.1 Q9VSK2 R-DME-5654738 Signaling by FGFR2 XP_046677339.1 Q9VSK2 R-DME-5654741 Signaling by FGFR3 XP_046677339.1 Q9VSK2 R-DME-5654743 Signaling by FGFR4 XP_046677339.1 Q9VSK2 R-DME-8848021 Signaling by PTK6 XP_046677339.1 Q9VSK2 R-DME-8849469 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 XP_046677339.1 Q9VSK2 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046677339.1 Q9VSK2 R-DME-8856828 Clathrin-mediated endocytosis XP_046677339.1 Q9VSK2 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046677339.1 Q9VSK2 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046677339.1 Q9VSK2 R-DME-9006936 Signaling by TGFB family members XP_046677339.1 Q9VSK2 R-DME-912631 Regulation of signaling by CBL XP_046677339.1 Q9VSK2 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046677339.1 Q9VSK2 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046671962.1 Q9NHX6 R-DME-350379 Homo-/heterophilic binding of transmembrane components XP_046671962.1 Q9NHX6 R-DME-350431 Planar Cell Polarity pathway XP_046671962.1 Q9NHX6 R-DME-5252538 Drosophila signaling pathways XP_046672594.1 Q9Y109 R-DME-392499 Metabolism of proteins XP_046672594.1 Q9Y109 R-DME-72766 Translation XP_046672594.1 Q9Y109 R-DME-9948299 Ribosome-associated quality control XP_046672594.1 Q9Y109 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046674133.1 Q9VSE8 R-DME-1430728 Metabolism XP_046674133.1 Q9VSE8 R-DME-156580 Phase II - Conjugation of compounds XP_046674133.1 Q9VSE8 R-DME-156588 Glucuronidation XP_046674133.1 Q9VSE8 R-DME-1630316 Glycosaminoglycan metabolism XP_046674133.1 Q9VSE8 R-DME-173599 Formation of the active cofactor, UDP-glucuronate XP_046674133.1 Q9VSE8 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046674133.1 Q9VSE8 R-DME-211859 Biological oxidations XP_046674133.1 Q9VSE8 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682452.1 Q9VSF3 R-DME-1280218 Adaptive Immune System XP_046682452.1 Q9VSF3 R-DME-162582 Signal Transduction XP_046682452.1 Q9VSF3 R-DME-168256 Immune System XP_046682452.1 Q9VSF3 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046682452.1 Q9VSF3 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046682452.1 Q9VSF3 R-DME-392499 Metabolism of proteins XP_046682452.1 Q9VSF3 R-DME-597592 Post-translational protein modification XP_046682452.1 Q9VSF3 R-DME-8951664 Neddylation XP_046682452.1 Q9VSF3 R-DME-9006936 Signaling by TGFB family members XP_046682452.1 Q9VSF3 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046682452.1 Q9VSF3 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046681198.1 A0A4D6K823 R-DME-162582 Signal Transduction XP_046681198.1 A0A4D6K823 R-DME-195721 Signaling by WNT XP_046681198.1 A0A4D6K823 R-DME-3858494 Beta-catenin independent WNT signaling XP_046681198.1 A0A4D6K823 R-DME-4086398 Ca2+ pathway XP_046667921.1 Q8IQ97 R-DME-162582 Signal Transduction XP_046667921.1 Q8IQ97 R-DME-193648 NRAGE signals death through JNK XP_046667921.1 Q8IQ97 R-DME-193704 p75 NTR receptor-mediated signalling XP_046667921.1 Q8IQ97 R-DME-194315 Signaling by Rho GTPases XP_046667921.1 Q8IQ97 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046667921.1 Q8IQ97 R-DME-372790 Signaling by GPCR XP_046667921.1 Q8IQ97 R-DME-388396 GPCR downstream signalling XP_046667921.1 Q8IQ97 R-DME-416482 G alpha (12/13) signalling events XP_046667921.1 Q8IQ97 R-DME-73887 Death Receptor Signaling XP_046667921.1 Q8IQ97 R-DME-8980692 RHOA GTPase cycle XP_046667921.1 Q8IQ97 R-DME-9012999 RHO GTPase cycle XP_046667921.1 Q8IQ97 R-DME-9013148 CDC42 GTPase cycle XP_046667921.1 Q8IQ97 R-DME-9013149 RAC1 GTPase cycle XP_046667921.1 Q8IQ97 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046660714.1 Q9VS85 R-DME-162582 Signal Transduction XP_046660714.1 Q9VS85 R-DME-177929 Signaling by EGFR XP_046660714.1 Q9VS85 R-DME-182971 EGFR downregulation XP_046660714.1 Q9VS85 R-DME-199991 Membrane Trafficking XP_046660714.1 Q9VS85 R-DME-5653656 Vesicle-mediated transport XP_046660714.1 Q9VS85 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046660714.1 Q9VS85 R-DME-8856828 Clathrin-mediated endocytosis XP_046660714.1 Q9VS85 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046682560.1 Q9VS97 R-DME-168249 Innate Immune System XP_046682560.1 Q9VS97 R-DME-168256 Immune System XP_046682560.1 Q9VS97 R-DME-6798695 Neutrophil degranulation XP_046682560.1 Q9VS97 R-DME-6803157 Antimicrobial peptides XP_046661909.1 Q9VRV8 R-DME-1852241 Organelle biogenesis and maintenance XP_046661909.1 Q9VRV8 R-DME-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA XP_046661909.1 Q9VRV8 R-DME-450531 Regulation of mRNA stability by proteins that bind AU-rich elements XP_046661909.1 Q9VRV8 R-DME-5617833 Cilium Assembly XP_046661909.1 Q9VRV8 R-DME-5620924 Intraflagellar transport XP_046661909.1 Q9VRV8 R-DME-8953854 Metabolism of RNA XP_046661909.1 Q9VRV8 R-DME-9975921 Assembly of the 9+0 primary cilium XP_046687389.1 Q9VRU1 R-DME-1430728 Metabolism XP_046687389.1 Q9VRU1 R-DME-70370 Galactose catabolism XP_046687389.1 Q9VRU1 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682590.1 Q9V470 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682590.1 Q9V470 R-DME-1430728 Metabolism XP_046682590.1 Q9V470 R-DME-392499 Metabolism of proteins XP_046682590.1 Q9V470 R-DME-71403 Citric acid cycle (TCA cycle) XP_046682590.1 Q9V470 R-DME-9837999 Mitochondrial protein degradation XP_046659763.1 Q9VRL0 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659763.1 Q9VRL0 R-DME-1430728 Metabolism XP_046659763.1 Q9VRL0 R-DME-611105 Respiratory electron transport XP_046659763.1 Q9VRL0 R-DME-9865881 Complex III assembly XP_046659764.1 Q9VRL1 R-DME-1280215 Cytokine Signaling in Immune system XP_046659764.1 Q9VRL1 R-DME-1280218 Adaptive Immune System XP_046659764.1 Q9VRL1 R-DME-1632852 Macroautophagy XP_046659764.1 Q9VRL1 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046659764.1 Q9VRL1 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046659764.1 Q9VRL1 R-DME-166166 MyD88-independent TLR4 cascade XP_046659764.1 Q9VRL1 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046659764.1 Q9VRL1 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046659764.1 Q9VRL1 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046659764.1 Q9VRL1 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046659764.1 Q9VRL1 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046659764.1 Q9VRL1 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046659764.1 Q9VRL1 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046659764.1 Q9VRL1 R-DME-168249 Innate Immune System XP_046659764.1 Q9VRL1 R-DME-168256 Immune System XP_046659764.1 Q9VRL1 R-DME-168898 Toll-like Receptor Cascades XP_046659764.1 Q9VRL1 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046659764.1 Q9VRL1 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046659764.1 Q9VRL1 R-DME-209459 Imd pathway XP_046659764.1 Q9VRL1 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046659764.1 Q9VRL1 R-DME-446652 Interleukin-1 family signaling XP_046659764.1 Q9VRL1 R-DME-449147 Signaling by Interleukins XP_046659764.1 Q9VRL1 R-DME-5205647 Mitophagy XP_046659764.1 Q9VRL1 R-DME-5205685 PINK1-PRKN Mediated Mitophagy XP_046659764.1 Q9VRL1 R-DME-5252538 Drosophila signaling pathways XP_046659764.1 Q9VRL1 R-DME-9020702 Interleukin-1 signaling XP_046659764.1 Q9VRL1 R-DME-937039 IRAK1 recruits IKK complex XP_046659764.1 Q9VRL1 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046659764.1 Q9VRL1 R-DME-9612973 Autophagy XP_046659764.1 Q9VRL1 R-DME-9646399 Aggrephagy XP_046659764.1 Q9VRL1 R-DME-9663891 Selective autophagy XP_046659764.1 Q9VRL1 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046659764.1 Q9VRL1 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046659764.1 Q9VRL1 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046659764.1 Q9VRL1 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046659764.1 Q9VRL1 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046659764.1 Q9VRL1 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046670058.1 Q9VRK9 R-DME-109582 Hemostasis XP_046670058.1 Q9VRK9 R-DME-162582 Signal Transduction XP_046670058.1 Q9VRK9 R-DME-5358351 Signaling by Hedgehog XP_046670058.1 Q9VRK9 R-DME-5610787 Hedgehog 'off' state XP_046670058.1 Q9VRK9 R-DME-983189 Kinesins XP_046670058.1 Q9VRK9 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046678266.1 Q9VRG7 R-DME-1640170 Cell Cycle XP_046678266.1 Q9VRG7 R-DME-2980766 Nuclear Envelope Breakdown XP_046678266.1 Q9VRG7 R-DME-4419969 Depolymerization of the Nuclear Lamina XP_046678266.1 Q9VRG7 R-DME-68875 Mitotic Prophase XP_046678266.1 Q9VRG7 R-DME-68886 M Phase XP_046678266.1 Q9VRG7 R-DME-69278 Cell Cycle, Mitotic XP_046661753.1 Q9VR99 R-DME-72163 mRNA Splicing - Major Pathway XP_046661753.1 Q9VR99 R-DME-72172 mRNA Splicing XP_046661753.1 Q9VR99 R-DME-72203 Processing of Capped Intron-Containing Pre-mRNA XP_046661753.1 Q9VR99 R-DME-8953854 Metabolism of RNA XP_046683524.1 Q9VRA2 R-DME-1430728 Metabolism XP_046683524.1 Q9VRA2 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046683524.1 Q9VRA2 R-DME-196854 Metabolism of vitamins and cofactors XP_046683524.1 Q9VRA2 R-DME-947581 Molybdenum cofactor biosynthesis XP_046673530.1 Q9V3Q6 R-DME-1280215 Cytokine Signaling in Immune system XP_046673530.1 Q9V3Q6 R-DME-162582 Signal Transduction XP_046673530.1 Q9V3Q6 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046673530.1 Q9V3Q6 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046673530.1 Q9V3Q6 R-DME-166166 MyD88-independent TLR4 cascade XP_046673530.1 Q9V3Q6 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046673530.1 Q9V3Q6 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046673530.1 Q9V3Q6 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046673530.1 Q9V3Q6 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046673530.1 Q9V3Q6 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046673530.1 Q9V3Q6 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046673530.1 Q9V3Q6 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046673530.1 Q9V3Q6 R-DME-168249 Innate Immune System XP_046673530.1 Q9V3Q6 R-DME-168256 Immune System XP_046673530.1 Q9V3Q6 R-DME-168898 Toll-like Receptor Cascades XP_046673530.1 Q9V3Q6 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046673530.1 Q9V3Q6 R-DME-195721 Signaling by WNT XP_046673530.1 Q9V3Q6 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046673530.1 Q9V3Q6 R-DME-209459 Imd pathway XP_046673530.1 Q9V3Q6 R-DME-3858494 Beta-catenin independent WNT signaling XP_046673530.1 Q9V3Q6 R-DME-4086398 Ca2+ pathway XP_046673530.1 Q9V3Q6 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046673530.1 Q9V3Q6 R-DME-446652 Interleukin-1 family signaling XP_046673530.1 Q9V3Q6 R-DME-448424 Interleukin-17 signaling XP_046673530.1 Q9V3Q6 R-DME-449147 Signaling by Interleukins XP_046673530.1 Q9V3Q6 R-DME-450294 MAP kinase activation XP_046673530.1 Q9V3Q6 R-DME-450302 activated TAK1 mediates p38 MAPK activation XP_046673530.1 Q9V3Q6 R-DME-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 XP_046673530.1 Q9V3Q6 R-DME-5252538 Drosophila signaling pathways XP_046673530.1 Q9V3Q6 R-DME-9020702 Interleukin-1 signaling XP_046673530.1 Q9V3Q6 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046673530.1 Q9V3Q6 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046673530.1 Q9V3Q6 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046673530.1 Q9V3Q6 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046679598.1 Q8IQ27 R-DME-392499 Metabolism of proteins XP_046679598.1 Q8IQ27 R-DME-5688426 Deubiquitination XP_046679598.1 Q8IQ27 R-DME-5689880 Ub-specific processing proteases XP_046679598.1 Q8IQ27 R-DME-597592 Post-translational protein modification XP_046664791.1 Q9VR25 R-DME-109582 Hemostasis XP_046664791.1 Q9VR25 R-DME-1266738 Developmental Biology XP_046664791.1 Q9VR25 R-DME-1430728 Metabolism XP_046664791.1 Q9VR25 R-DME-1474228 Degradation of the extracellular matrix XP_046664791.1 Q9VR25 R-DME-1474244 Extracellular matrix organization XP_046664791.1 Q9VR25 R-DME-162582 Signal Transduction XP_046664791.1 Q9VR25 R-DME-1630316 Glycosaminoglycan metabolism XP_046664791.1 Q9VR25 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046664791.1 Q9VR25 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046664791.1 Q9VR25 R-DME-2022928 HS-GAG biosynthesis XP_046664791.1 Q9VR25 R-DME-2024096 HS-GAG degradation XP_046664791.1 Q9VR25 R-DME-216083 Integrin cell surface interactions XP_046664791.1 Q9VR25 R-DME-3000171 Non-integrin membrane-ECM interactions XP_046664791.1 Q9VR25 R-DME-3000178 ECM proteoglycans XP_046664791.1 Q9VR25 R-DME-373760 L1CAM interactions XP_046664791.1 Q9VR25 R-DME-375165 NCAM signaling for neurite out-growth XP_046664791.1 Q9VR25 R-DME-419037 NCAM1 interactions XP_046664791.1 Q9VR25 R-DME-422475 Axon guidance XP_046664791.1 Q9VR25 R-DME-445144 Signal transduction by L1 XP_046664791.1 Q9VR25 R-DME-5673001 RAF/MAP kinase cascade XP_046664791.1 Q9VR25 R-DME-5683057 MAPK family signaling cascades XP_046664791.1 Q9VR25 R-DME-5684996 MAPK1/MAPK3 signaling XP_046664791.1 Q9VR25 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046664791.1 Q9VR25 R-DME-9675108 Nervous system development XP_046664791.1 Q9VR25 R-DME-9769739 Regulation of clotting cascade XP_046664791.1 Q9VR25 R-DME-9769740 Coagulation pathway XP_046664791.1 Q9VR25 R-DME-9913351 Formation of the dystrophin-glycoprotein complex (DGC) XP_046667839.1 Q9VR00 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046667839.1 Q9VR00 R-DME-1430728 Metabolism XP_046667839.1 Q9VR00 R-DME-392499 Metabolism of proteins XP_046667839.1 Q9VR00 R-DME-611105 Respiratory electron transport XP_046667839.1 Q9VR00 R-DME-6799198 Complex I biogenesis XP_046667839.1 Q9VR00 R-DME-9837999 Mitochondrial protein degradation XP_046664422.1 Q9VQW7 R-DME-1500931 Cell-Cell communication XP_046664422.1 Q9VQW7 R-DME-373753 Nephrin family interactions XP_046663587.1 P33450 R-DME-350379 Homo-/heterophilic binding of transmembrane components XP_046663587.1 P33450 R-DME-350431 Planar Cell Polarity pathway XP_046663587.1 P33450 R-DME-390023 Subcellular localisation of D XP_046663587.1 P33450 R-DME-390146 Hippo/Warts pathway XP_046663587.1 P33450 R-DME-390150 DS ligand bound to FT receptor XP_046663587.1 P33450 R-DME-5252538 Drosophila signaling pathways XP_046673860.1 Q9VQX4 R-DME-1430728 Metabolism XP_046673860.1 Q9VQX4 R-DME-168249 Innate Immune System XP_046673860.1 Q9VQX4 R-DME-168256 Immune System XP_046673860.1 Q9VQX4 R-DME-196807 Nicotinate metabolism XP_046673860.1 Q9VQX4 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046673860.1 Q9VQX4 R-DME-196854 Metabolism of vitamins and cofactors XP_046673860.1 Q9VQX4 R-DME-6798695 Neutrophil degranulation XP_046660628.1 Q9VQR2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046660628.1 Q9VQR2 R-DME-1430728 Metabolism XP_046660628.1 Q9VQR2 R-DME-611105 Respiratory electron transport XP_046660628.1 Q9VQR2 R-DME-6799198 Complex I biogenesis XP_046665614.1 Q8IA42 R-DME-392499 Metabolism of proteins XP_046665614.1 Q8IA42 R-DME-5173105 O-linked glycosylation XP_046665614.1 Q8IA42 R-DME-597592 Post-translational protein modification XP_046665614.1 Q8IA42 R-DME-913709 O-linked glycosylation of mucins XP_046663563.1 P42003 R-DME-162582 Signal Transduction XP_046663563.1 P42003 R-DME-201451 Signaling by BMP XP_046663563.1 P42003 R-DME-212436 Generic Transcription Pathway XP_046663563.1 P42003 R-DME-392499 Metabolism of proteins XP_046663563.1 P42003 R-DME-5688426 Deubiquitination XP_046663563.1 P42003 R-DME-5689880 Ub-specific processing proteases XP_046663563.1 P42003 R-DME-597592 Post-translational protein modification XP_046663563.1 P42003 R-DME-73857 RNA Polymerase II Transcription XP_046663563.1 P42003 R-DME-74160 Gene expression (Transcription) XP_046663563.1 P42003 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046663563.1 P42003 R-DME-8941326 RUNX2 regulates bone development XP_046663563.1 P42003 R-DME-9006936 Signaling by TGFB family members XP_046663969.1 Q9VQM2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046663969.1 Q9VQM2 R-DME-1430728 Metabolism XP_046663969.1 Q9VQM2 R-DME-168249 Innate Immune System XP_046663969.1 Q9VQM2 R-DME-168256 Immune System XP_046663969.1 Q9VQM2 R-DME-611105 Respiratory electron transport XP_046663969.1 Q9VQM2 R-DME-6798695 Neutrophil degranulation XP_046663969.1 Q9VQM2 R-DME-6799198 Complex I biogenesis XP_046678916.1 Q9VQG2 R-DME-1236394 Signaling by ERBB4 XP_046678916.1 Q9VQG2 R-DME-1251985 Nuclear signaling by ERBB4 XP_046678916.1 Q9VQG2 R-DME-1266738 Developmental Biology XP_046678916.1 Q9VQG2 R-DME-162582 Signal Transduction XP_046678916.1 Q9VQG2 R-DME-2682334 EPH-Ephrin signaling XP_046678916.1 Q9VQG2 R-DME-3928665 EPH-ephrin mediated repulsion of cells XP_046678916.1 Q9VQG2 R-DME-422475 Axon guidance XP_046678916.1 Q9VQG2 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046678916.1 Q9VQG2 R-DME-9675108 Nervous system development XP_046681969.1 Q9VQH1 R-DME-1430728 Metabolism XP_046681969.1 Q9VQH1 R-DME-70263 Gluconeogenesis XP_046681969.1 Q9VQH1 R-DME-70326 Glucose metabolism XP_046681969.1 Q9VQH1 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046669548.1 Q9VQD7 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046669548.1 Q9VQD7 R-DME-1430728 Metabolism XP_046669548.1 Q9VQD7 R-DME-611105 Respiratory electron transport XP_046669548.1 Q9VQD7 R-DME-6799198 Complex I biogenesis XP_046663745.1 P07713 R-DME-109582 Hemostasis XP_046663745.1 P07713 R-DME-114608 Platelet degranulation XP_046663745.1 P07713 R-DME-1474244 Extracellular matrix organization XP_046663745.1 P07713 R-DME-1566948 Elastic fibre formation XP_046663745.1 P07713 R-DME-162582 Signal Transduction XP_046663745.1 P07713 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046663745.1 P07713 R-DME-201451 Signaling by BMP XP_046663745.1 P07713 R-DME-212436 Generic Transcription Pathway XP_046663745.1 P07713 R-DME-2129379 Molecules associated with elastic fibres XP_046663745.1 P07713 R-DME-2173788 Downregulation of TGF-beta receptor signaling XP_046663745.1 P07713 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046663745.1 P07713 R-DME-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) XP_046663745.1 P07713 R-DME-3000170 Syndecan interactions XP_046663745.1 P07713 R-DME-3000171 Non-integrin membrane-ECM interactions XP_046663745.1 P07713 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046663745.1 P07713 R-DME-392499 Metabolism of proteins XP_046663745.1 P07713 R-DME-597592 Post-translational protein modification XP_046663745.1 P07713 R-DME-73857 RNA Polymerase II Transcription XP_046663745.1 P07713 R-DME-74160 Gene expression (Transcription) XP_046663745.1 P07713 R-DME-76002 Platelet activation, signaling and aggregation XP_046663745.1 P07713 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046663745.1 P07713 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046663745.1 P07713 R-DME-8941855 RUNX3 regulates CDKN1A transcription XP_046663745.1 P07713 R-DME-8941858 Regulation of RUNX3 expression and activity XP_046663745.1 P07713 R-DME-8951936 RUNX3 regulates p14-ARF XP_046663745.1 P07713 R-DME-8957275 Post-translational protein phosphorylation XP_046663745.1 P07713 R-DME-9006936 Signaling by TGFB family members XP_046663745.1 P07713 R-DME-9839373 Signaling by TGFBR3 XP_046663745.1 P07713 R-DME-9839389 TGFBR3 regulates TGF-beta signaling XP_046675586.1 Q9Y0H4 R-DME-1236394 Signaling by ERBB4 XP_046675586.1 Q9Y0H4 R-DME-1253288 Downregulation of ERBB4 signaling XP_046675586.1 Q9Y0H4 R-DME-1257604 PIP3 activates AKT signaling XP_046675586.1 Q9Y0H4 R-DME-1280218 Adaptive Immune System XP_046675586.1 Q9Y0H4 R-DME-157118 Signaling by NOTCH XP_046675586.1 Q9Y0H4 R-DME-162582 Signal Transduction XP_046675586.1 Q9Y0H4 R-DME-168256 Immune System XP_046675586.1 Q9Y0H4 R-DME-194315 Signaling by Rho GTPases XP_046675586.1 Q9Y0H4 R-DME-1980143 Signaling by NOTCH1 XP_046675586.1 Q9Y0H4 R-DME-2122948 Activated NOTCH1 Transmits Signal to the Nucleus XP_046675586.1 Q9Y0H4 R-DME-212436 Generic Transcription Pathway XP_046675586.1 Q9Y0H4 R-DME-6807070 PTEN Regulation XP_046675586.1 Q9Y0H4 R-DME-73857 RNA Polymerase II Transcription XP_046675586.1 Q9Y0H4 R-DME-74160 Gene expression (Transcription) XP_046675586.1 Q9Y0H4 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046675586.1 Q9Y0H4 R-DME-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs XP_046675586.1 Q9Y0H4 R-DME-8948751 Regulation of PTEN stability and activity XP_046675586.1 Q9Y0H4 R-DME-9006925 Intracellular signaling by second messengers XP_046675586.1 Q9Y0H4 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046675586.1 Q9Y0H4 R-DME-9012999 RHO GTPase cycle XP_046675586.1 Q9Y0H4 R-DME-9013406 RHOQ GTPase cycle XP_046675586.1 Q9Y0H4 R-DME-9013420 RHOU GTPase cycle XP_046675586.1 Q9Y0H4 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046675586.1 Q9Y0H4 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046675586.1 Q9Y0H4 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046678700.1 P15007 R-DME-1430728 Metabolism XP_046678700.1 P15007 R-DME-70171 Glycolysis XP_046678700.1 P15007 R-DME-70263 Gluconeogenesis XP_046678700.1 P15007 R-DME-70326 Glucose metabolism XP_046678700.1 P15007 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046676904.1 Q9VQ29 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046676904.1 Q9VQ29 R-DME-1430728 Metabolism XP_046676904.1 Q9VQ29 R-DME-611105 Respiratory electron transport XP_046676904.1 Q9VQ29 R-DME-9865881 Complex III assembly XP_046663734.1 P25455 R-DME-111885 Opioid Signalling XP_046663734.1 P25455 R-DME-112040 G-protein mediated events XP_046663734.1 P25455 R-DME-112043 PLC beta mediated events XP_046663734.1 P25455 R-DME-1430728 Metabolism XP_046663734.1 P25455 R-DME-1483249 Inositol phosphate metabolism XP_046663734.1 P25455 R-DME-162582 Signal Transduction XP_046663734.1 P25455 R-DME-1855204 Synthesis of IP3 and IP4 in the cytosol XP_046663734.1 P25455 R-DME-372790 Signaling by GPCR XP_046663734.1 P25455 R-DME-388396 GPCR downstream signalling XP_046663734.1 P25455 R-DME-416476 G alpha (q) signalling events XP_046663734.1 P25455 R-DME-418594 G alpha (i) signalling events XP_046664780.1 Q07436 R-DME-390146 Hippo/Warts pathway XP_046664780.1 Q07436 R-DME-390150 DS ligand bound to FT receptor XP_046664780.1 Q07436 R-DME-451806 Phosphorylation-independent inhibition of YKI XP_046664780.1 Q07436 R-DME-5252538 Drosophila signaling pathways XP_046676574.1 Q9VPQ6 R-DME-109582 Hemostasis XP_046676574.1 Q9VPQ6 R-DME-212436 Generic Transcription Pathway XP_046676574.1 Q9VPQ6 R-DME-73857 RNA Polymerase II Transcription XP_046676574.1 Q9VPQ6 R-DME-74160 Gene expression (Transcription) XP_046676574.1 Q9VPQ6 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046676574.1 Q9VPQ6 R-DME-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function XP_046676574.1 Q9VPQ6 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046680895.1 Q9VPR4 R-DME-1280218 Adaptive Immune System XP_046680895.1 Q9VPR4 R-DME-1500931 Cell-Cell communication XP_046680895.1 Q9VPR4 R-DME-168256 Immune System XP_046680895.1 Q9VPR4 R-DME-418990 Adherens junctions interactions XP_046680895.1 Q9VPR4 R-DME-421270 Cell-cell junction organization XP_046680895.1 Q9VPR4 R-DME-446728 Cell junction organization XP_046680895.1 Q9VPR4 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046680895.1 Q9VPR4 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046680895.1 Q9VPR4 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046688440.1 Q7KNM2 R-DME-1430728 Metabolism XP_046688440.1 Q7KNM2 R-DME-196791 Vitamin D (calciferol) metabolism XP_046688440.1 Q7KNM2 R-DME-2990846 SUMOylation XP_046688440.1 Q7KNM2 R-DME-3108214 SUMOylation of DNA damage response and repair proteins XP_046688440.1 Q7KNM2 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046688440.1 Q7KNM2 R-DME-3232118 SUMOylation of transcription factors XP_046688440.1 Q7KNM2 R-DME-3899300 SUMOylation of transcription cofactors XP_046688440.1 Q7KNM2 R-DME-392499 Metabolism of proteins XP_046688440.1 Q7KNM2 R-DME-4085377 SUMOylation of SUMOylation proteins XP_046688440.1 Q7KNM2 R-DME-4090294 SUMOylation of intracellular receptors XP_046688440.1 Q7KNM2 R-DME-4551638 SUMOylation of chromatin organization proteins XP_046688440.1 Q7KNM2 R-DME-4570464 SUMOylation of RNA binding proteins XP_046688440.1 Q7KNM2 R-DME-4615885 SUMOylation of DNA replication proteins XP_046688440.1 Q7KNM2 R-DME-4755510 SUMOylation of immune response proteins XP_046688440.1 Q7KNM2 R-DME-556833 Metabolism of lipids XP_046688440.1 Q7KNM2 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046688440.1 Q7KNM2 R-DME-5696398 Nucleotide Excision Repair XP_046688440.1 Q7KNM2 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046688440.1 Q7KNM2 R-DME-597592 Post-translational protein modification XP_046688440.1 Q7KNM2 R-DME-73894 DNA Repair XP_046688440.1 Q7KNM2 R-DME-8957322 Metabolism of steroids XP_046672908.1 P91682 R-DME-162582 Signal Transduction XP_046672908.1 P91682 R-DME-1852241 Organelle biogenesis and maintenance XP_046672908.1 P91682 R-DME-209214 Phosphorylation of SMO XP_046672908.1 P91682 R-DME-209338 Assembly of the 'signalling complexes' XP_046672908.1 P91682 R-DME-209392 Hedgehog pathway XP_046672908.1 P91682 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046672908.1 P91682 R-DME-216119 Activation of CI XP_046672908.1 P91682 R-DME-216217 Activation of SMO XP_046672908.1 P91682 R-DME-5252538 Drosophila signaling pathways XP_046672908.1 P91682 R-DME-5358351 Signaling by Hedgehog XP_046672908.1 P91682 R-DME-5610787 Hedgehog 'off' state XP_046672908.1 P91682 R-DME-5617833 Cilium Assembly XP_046672908.1 P91682 R-DME-5620920 Cargo trafficking to the periciliary membrane XP_046672908.1 P91682 R-DME-5620922 BBSome-mediated cargo-targeting to cilium XP_046672908.1 P91682 R-DME-5632684 Hedgehog 'on' state XP_046672908.1 P91682 R-DME-5635838 Activation of SMO XP_046672908.1 P91682 R-DME-9975921 Assembly of the 9+0 primary cilium XP_046684099.1 O18683 R-DME-110478 Insulin signaling pathway XP_046684099.1 O18683 R-DME-110526 Insulin receptor mediated signaling XP_046684099.1 O18683 R-DME-5252538 Drosophila signaling pathways XP_046684099.1 Q7KTZ2 R-DME-109582 Hemostasis XP_046684099.1 Q7KTZ2 R-DME-109704 PI3K Cascade XP_046684099.1 Q7KTZ2 R-DME-112399 IRS-mediated signalling XP_046684099.1 Q7KTZ2 R-DME-114604 GPVI-mediated activation cascade XP_046684099.1 Q7KTZ2 R-DME-1227986 Signaling by ERBB2 XP_046684099.1 Q7KTZ2 R-DME-1236394 Signaling by ERBB4 XP_046684099.1 Q7KTZ2 R-DME-1250342 PI3K events in ERBB4 signaling XP_046684099.1 Q7KTZ2 R-DME-1257604 PIP3 activates AKT signaling XP_046684099.1 Q7KTZ2 R-DME-1266738 Developmental Biology XP_046684099.1 Q7KTZ2 R-DME-1280215 Cytokine Signaling in Immune system XP_046684099.1 Q7KTZ2 R-DME-1280218 Adaptive Immune System XP_046684099.1 Q7KTZ2 R-DME-1430728 Metabolism XP_046684099.1 Q7KTZ2 R-DME-1483255 PI Metabolism XP_046684099.1 Q7KTZ2 R-DME-1483257 Phospholipid metabolism XP_046684099.1 Q7KTZ2 R-DME-162582 Signal Transduction XP_046684099.1 Q7KTZ2 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046684099.1 Q7KTZ2 R-DME-168249 Innate Immune System XP_046684099.1 Q7KTZ2 R-DME-168256 Immune System XP_046684099.1 Q7KTZ2 R-DME-177929 Signaling by EGFR XP_046684099.1 Q7KTZ2 R-DME-180292 GAB1 signalosome XP_046684099.1 Q7KTZ2 R-DME-186763 Downstream signal transduction XP_046684099.1 Q7KTZ2 R-DME-186797 Signaling by PDGF XP_046684099.1 Q7KTZ2 R-DME-190236 Signaling by FGFR XP_046684099.1 Q7KTZ2 R-DME-194138 Signaling by VEGF XP_046684099.1 Q7KTZ2 R-DME-194315 Signaling by Rho GTPases XP_046684099.1 Q7KTZ2 R-DME-1963642 PI3K events in ERBB2 signaling XP_046684099.1 Q7KTZ2 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046684099.1 Q7KTZ2 R-DME-201556 Signaling by ALK XP_046684099.1 Q7KTZ2 R-DME-202733 Cell surface interactions at the vascular wall XP_046684099.1 Q7KTZ2 R-DME-210993 Tie2 Signaling XP_046684099.1 Q7KTZ2 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046684099.1 Q7KTZ2 R-DME-2428924 IGF1R signaling cascade XP_046684099.1 Q7KTZ2 R-DME-2428928 IRS-related events triggered by IGF1R XP_046684099.1 Q7KTZ2 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046684099.1 Q7KTZ2 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046684099.1 Q7KTZ2 R-DME-422475 Axon guidance XP_046684099.1 Q7KTZ2 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046684099.1 Q7KTZ2 R-DME-449147 Signaling by Interleukins XP_046684099.1 Q7KTZ2 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046684099.1 Q7KTZ2 R-DME-556833 Metabolism of lipids XP_046684099.1 Q7KTZ2 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046684099.1 Q7KTZ2 R-DME-5654689 PI-3K cascade:FGFR1 XP_046684099.1 Q7KTZ2 R-DME-5654695 PI-3K cascade:FGFR2 XP_046684099.1 Q7KTZ2 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046684099.1 Q7KTZ2 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046684099.1 Q7KTZ2 R-DME-5654710 PI-3K cascade:FGFR3 XP_046684099.1 Q7KTZ2 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046684099.1 Q7KTZ2 R-DME-5654720 PI-3K cascade:FGFR4 XP_046684099.1 Q7KTZ2 R-DME-5654736 Signaling by FGFR1 XP_046684099.1 Q7KTZ2 R-DME-5654738 Signaling by FGFR2 XP_046684099.1 Q7KTZ2 R-DME-5654741 Signaling by FGFR3 XP_046684099.1 Q7KTZ2 R-DME-5654743 Signaling by FGFR4 XP_046684099.1 Q7KTZ2 R-DME-5673001 RAF/MAP kinase cascade XP_046684099.1 Q7KTZ2 R-DME-5683057 MAPK family signaling cascades XP_046684099.1 Q7KTZ2 R-DME-5684996 MAPK1/MAPK3 signaling XP_046684099.1 Q7KTZ2 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046684099.1 Q7KTZ2 R-DME-74751 Insulin receptor signalling cascade XP_046684099.1 Q7KTZ2 R-DME-74752 Signaling by Insulin receptor XP_046684099.1 Q7KTZ2 R-DME-76002 Platelet activation, signaling and aggregation XP_046684099.1 Q7KTZ2 R-DME-8853659 RET signaling XP_046684099.1 Q7KTZ2 R-DME-8980692 RHOA GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9006925 Intracellular signaling by second messengers XP_046684099.1 Q7KTZ2 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046684099.1 Q7KTZ2 R-DME-9012999 RHO GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9013148 CDC42 GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9013149 RAC1 GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9013409 RHOJ GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9013420 RHOU GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9013423 RAC3 GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9013424 RHOV GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-9035034 RHOF GTPase cycle XP_046684099.1 Q7KTZ2 R-DME-912631 Regulation of signaling by CBL XP_046684099.1 Q7KTZ2 R-DME-9675108 Nervous system development XP_046684099.1 Q7KTZ2 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046684099.1 Q7KTZ2 R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers XP_046684099.1 Q7KTZ2 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046665119.1 Q9VPE2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046665119.1 Q9VPE2 R-DME-1430728 Metabolism XP_046665119.1 Q9VPE2 R-DME-611105 Respiratory electron transport XP_046665119.1 Q9VPE2 R-DME-6799198 Complex I biogenesis XP_046676605.1 Q9V3Z1 R-DME-109704 PI3K Cascade XP_046676605.1 Q9V3Z1 R-DME-112399 IRS-mediated signalling XP_046676605.1 Q9V3Z1 R-DME-1257604 PIP3 activates AKT signaling XP_046676605.1 Q9V3Z1 R-DME-1280218 Adaptive Immune System XP_046676605.1 Q9V3Z1 R-DME-162582 Signal Transduction XP_046676605.1 Q9V3Z1 R-DME-165158 Activation of AKT2 XP_046676605.1 Q9V3Z1 R-DME-168256 Immune System XP_046676605.1 Q9V3Z1 R-DME-194138 Signaling by VEGF XP_046676605.1 Q9V3Z1 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046676605.1 Q9V3Z1 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046676605.1 Q9V3Z1 R-DME-2428924 IGF1R signaling cascade XP_046676605.1 Q9V3Z1 R-DME-2428928 IRS-related events triggered by IGF1R XP_046676605.1 Q9V3Z1 R-DME-388841 Regulation of T cell activation by CD28 family XP_046676605.1 Q9V3Z1 R-DME-389356 Co-stimulation by CD28 XP_046676605.1 Q9V3Z1 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046676605.1 Q9V3Z1 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046676605.1 Q9V3Z1 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046676605.1 Q9V3Z1 R-DME-74751 Insulin receptor signalling cascade XP_046676605.1 Q9V3Z1 R-DME-74752 Signaling by Insulin receptor XP_046676605.1 Q9V3Z1 R-DME-9006925 Intracellular signaling by second messengers XP_046676605.1 Q9V3Z1 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660376.1 P22817 R-DME-392499 Metabolism of proteins XP_046660376.1 P22817 R-DME-5688426 Deubiquitination XP_046660376.1 P22817 R-DME-5689880 Ub-specific processing proteases XP_046660376.1 P22817 R-DME-597592 Post-translational protein modification XP_046660376.1 P22817 R-DME-9033241 Peroxisomal protein import XP_046660376.1 P22817 R-DME-9609507 Protein localization XP_046665537.1 Q9VP87 R-DME-1430728 Metabolism XP_046665537.1 Q9VP87 R-DME-196854 Metabolism of vitamins and cofactors XP_046665537.1 Q9VP87 R-DME-2142789 Ubiquinol biosynthesis XP_046665537.1 Q9VP87 R-DME-8978934 Metabolism of cofactors XP_046680000.1 Q7KTX8 R-DME-212165 Epigenetic regulation of gene expression XP_046680000.1 Q7KTX8 R-DME-74160 Gene expression (Transcription) XP_046680000.1 Q7KTX8 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046680000.1 Q7KTX8 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046680000.1 Q7KTX8 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046680000.1 Q7KTX8 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046679007.1 P61209 R-DME-1430728 Metabolism XP_046679007.1 P61209 R-DME-1483255 PI Metabolism XP_046679007.1 P61209 R-DME-1483257 Phospholipid metabolism XP_046679007.1 P61209 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046679007.1 P61209 R-DME-1660514 Synthesis of PIPs at the Golgi membrane XP_046679007.1 P61209 R-DME-199977 ER to Golgi Anterograde Transport XP_046679007.1 P61209 R-DME-199991 Membrane Trafficking XP_046679007.1 P61209 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046679007.1 P61209 R-DME-382551 Transport of small molecules XP_046679007.1 P61209 R-DME-392499 Metabolism of proteins XP_046679007.1 P61209 R-DME-432720 Lysosome Vesicle Biogenesis XP_046679007.1 P61209 R-DME-432722 Golgi Associated Vesicle Biogenesis XP_046679007.1 P61209 R-DME-446203 Asparagine N-linked glycosylation XP_046679007.1 P61209 R-DME-556833 Metabolism of lipids XP_046679007.1 P61209 R-DME-5653656 Vesicle-mediated transport XP_046679007.1 P61209 R-DME-597592 Post-translational protein modification XP_046679007.1 P61209 R-DME-6807878 COPI-mediated anterograde transport XP_046679007.1 P61209 R-DME-6811434 COPI-dependent Golgi-to-ER retrograde traffic XP_046679007.1 P61209 R-DME-6811438 Intra-Golgi traffic XP_046679007.1 P61209 R-DME-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic XP_046679007.1 P61209 R-DME-8856688 Golgi-to-ER retrograde transport XP_046679007.1 P61209 R-DME-948021 Transport to the Golgi and subsequent modification XP_046679007.1 P61209 R-DME-9845576 Glycosphingolipid transport XP_046661296.1 Q9VNJ0 R-DME-1280218 Adaptive Immune System XP_046661296.1 Q9VNJ0 R-DME-168256 Immune System XP_046661296.1 Q9VNJ0 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046661296.1 Q9VNJ0 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046685552.1 Q9VND8 R-DME-110523 TOR signaling pathway XP_046685552.1 Q9VND8 R-DME-110526 Insulin receptor mediated signaling XP_046685552.1 Q9VND8 R-DME-1257604 PIP3 activates AKT signaling XP_046685552.1 Q9VND8 R-DME-162582 Signal Transduction XP_046685552.1 Q9VND8 R-DME-1632852 Macroautophagy XP_046685552.1 Q9VND8 R-DME-165159 MTOR signalling XP_046685552.1 Q9VND8 R-DME-166208 mTORC1-mediated signalling XP_046685552.1 Q9VND8 R-DME-212436 Generic Transcription Pathway XP_046685552.1 Q9VND8 R-DME-2262752 Cellular responses to stress XP_046685552.1 Q9VND8 R-DME-3700989 Transcriptional Regulation by TP53 XP_046685552.1 Q9VND8 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046685552.1 Q9VND8 R-DME-5252538 Drosophila signaling pathways XP_046685552.1 Q9VND8 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046685552.1 Q9VND8 R-DME-6807070 PTEN Regulation XP_046685552.1 Q9VND8 R-DME-73857 RNA Polymerase II Transcription XP_046685552.1 Q9VND8 R-DME-74160 Gene expression (Transcription) XP_046685552.1 Q9VND8 R-DME-8943724 Regulation of PTEN gene transcription XP_046685552.1 Q9VND8 R-DME-8953897 Cellular responses to stimuli XP_046685552.1 Q9VND8 R-DME-9006925 Intracellular signaling by second messengers XP_046685552.1 Q9VND8 R-DME-9612973 Autophagy XP_046685552.1 Q9VND8 R-DME-9639288 Amino acids regulate mTORC1 XP_046685552.1 Q9VND8 R-DME-9711097 Cellular response to starvation XP_046681049.1 Q24170 R-DME-209159 Assembly of the CI containing complexes XP_046681049.1 Q24170 R-DME-209190 Phosphorylation of CI XP_046681049.1 Q24170 R-DME-209214 Phosphorylation of SMO XP_046681049.1 Q24170 R-DME-209392 Hedgehog pathway XP_046681049.1 Q24170 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046681049.1 Q24170 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046681049.1 Q24170 R-DME-216217 Activation of SMO XP_046681049.1 Q24170 R-DME-432553 Phosphorylation of PER and TIM XP_046681049.1 Q24170 R-DME-432626 Circadian Clock pathway XP_046681049.1 Q24170 R-DME-5252538 Drosophila signaling pathways XP_046681049.1 Q24171 R-DME-162582 Signal Transduction XP_046681049.1 Q24171 R-DME-5673000 RAF activation XP_046681049.1 Q24171 R-DME-5673001 RAF/MAP kinase cascade XP_046681049.1 Q24171 R-DME-5674135 MAP2K and MAPK activation XP_046681049.1 Q24171 R-DME-5675221 Negative regulation of MAPK pathway XP_046681049.1 Q24171 R-DME-5683057 MAPK family signaling cascades XP_046681049.1 Q24171 R-DME-5684996 MAPK1/MAPK3 signaling XP_046685303.1 Q7JZB4 R-DME-392499 Metabolism of proteins XP_046685303.1 Q7JZB4 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046685303.1 Q7JZB4 R-DME-446203 Asparagine N-linked glycosylation XP_046685303.1 Q7JZB4 R-DME-446205 Synthesis of GDP-mannose XP_046685303.1 Q7JZB4 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046685303.1 Q7JZB4 R-DME-597592 Post-translational protein modification XP_046663866.1 Q9VN50 R-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression XP_046663866.1 Q9VN50 R-DME-392499 Metabolism of proteins XP_046663866.1 Q9VN50 R-DME-72613 Eukaryotic Translation Initiation XP_046663866.1 Q9VN50 R-DME-72649 Translation initiation complex formation XP_046663866.1 Q9VN50 R-DME-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S XP_046663866.1 Q9VN50 R-DME-72689 Formation of a pool of free 40S subunits XP_046663866.1 Q9VN50 R-DME-72695 Formation of the ternary complex, and subsequently, the 43S complex XP_046663866.1 Q9VN50 R-DME-72702 Ribosomal scanning and start codon recognition XP_046663866.1 Q9VN50 R-DME-72737 Cap-dependent Translation Initiation XP_046663866.1 Q9VN50 R-DME-72766 Translation XP_046675588.1 P22812 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046675588.1 P22812 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046675588.1 P22812 R-DME-209449 Toll pathway XP_046675588.1 P22812 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046675588.1 P22812 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046675588.1 P22812 R-DME-214862 Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' XP_046675588.1 P22812 R-DME-214863 Adaptor protein complex binds to TL receptor at the plasma membrane XP_046675588.1 P22812 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046675588.1 P22812 R-DME-214874 PLL kinase binds to TUB in the TL receptor 'signalling complex' XP_046675588.1 P22812 R-DME-5252538 Drosophila signaling pathways XP_046667073.1 Q8IPM1 R-DME-212165 Epigenetic regulation of gene expression XP_046667073.1 Q8IPM1 R-DME-74160 Gene expression (Transcription) XP_046667073.1 Q8IPM1 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046667073.1 Q8IPM1 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046667073.1 Q8IPM1 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046667073.1 Q8IPM1 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046686041.1 Q9VMU0 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046686041.1 Q9VMU0 R-DME-1430728 Metabolism XP_046686041.1 Q9VMU0 R-DME-611105 Respiratory electron transport XP_046686041.1 Q9VMU0 R-DME-6799198 Complex I biogenesis XP_046685663.1 Q6WV17 R-DME-199991 Membrane Trafficking XP_046685663.1 Q6WV17 R-DME-392499 Metabolism of proteins XP_046685663.1 Q6WV17 R-DME-5173105 O-linked glycosylation XP_046685663.1 Q6WV17 R-DME-5653656 Vesicle-mediated transport XP_046685663.1 Q6WV17 R-DME-597592 Post-translational protein modification XP_046685663.1 Q6WV17 R-DME-6811436 COPI-independent Golgi-to-ER retrograde traffic XP_046685663.1 Q6WV17 R-DME-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic XP_046685663.1 Q6WV17 R-DME-8856688 Golgi-to-ER retrograde transport XP_046685663.1 Q6WV17 R-DME-913709 O-linked glycosylation of mucins XP_046676488.1 Q9U9Q4 R-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression XP_046676488.1 Q9U9Q4 R-DME-392499 Metabolism of proteins XP_046676488.1 Q9U9Q4 R-DME-72613 Eukaryotic Translation Initiation XP_046676488.1 Q9U9Q4 R-DME-72649 Translation initiation complex formation XP_046676488.1 Q9U9Q4 R-DME-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S XP_046676488.1 Q9U9Q4 R-DME-72689 Formation of a pool of free 40S subunits XP_046676488.1 Q9U9Q4 R-DME-72695 Formation of the ternary complex, and subsequently, the 43S complex XP_046676488.1 Q9U9Q4 R-DME-72702 Ribosomal scanning and start codon recognition XP_046676488.1 Q9U9Q4 R-DME-72737 Cap-dependent Translation Initiation XP_046676488.1 Q9U9Q4 R-DME-72766 Translation XP_046680194.1 Q9VMS1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046680194.1 Q9VMS1 R-DME-1430728 Metabolism XP_046680194.1 Q9VMS1 R-DME-212436 Generic Transcription Pathway XP_046680194.1 Q9VMS1 R-DME-2262752 Cellular responses to stress XP_046680194.1 Q9VMS1 R-DME-3700989 Transcriptional Regulation by TP53 XP_046680194.1 Q9VMS1 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046680194.1 Q9VMS1 R-DME-611105 Respiratory electron transport XP_046680194.1 Q9VMS1 R-DME-73857 RNA Polymerase II Transcription XP_046680194.1 Q9VMS1 R-DME-74160 Gene expression (Transcription) XP_046680194.1 Q9VMS1 R-DME-8953897 Cellular responses to stimuli XP_046680194.1 Q9VMS1 R-DME-9707564 Cytoprotection by HMOX1 XP_046680194.1 Q9VMS1 R-DME-9711123 Cellular response to chemical stress XP_046680194.1 Q9VMS1 R-DME-9864848 Complex IV assembly XP_046681820.1 Q8IPK4 R-DME-1474244 Extracellular matrix organization XP_046681820.1 Q8IPK4 R-DME-1474290 Collagen formation XP_046681820.1 Q8IPK4 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046685031.1 Q9VMQ5 R-DME-1430728 Metabolism XP_046685031.1 Q9VMQ5 R-DME-196854 Metabolism of vitamins and cofactors XP_046685031.1 Q9VMQ5 R-DME-2142789 Ubiquinol biosynthesis XP_046685031.1 Q9VMQ5 R-DME-8978934 Metabolism of cofactors XP_046684305.1 P13706 R-DME-1430728 Metabolism XP_046684305.1 P13706 R-DME-1483166 Synthesis of PA XP_046684305.1 P13706 R-DME-1483206 Glycerophospholipid biosynthesis XP_046684305.1 P13706 R-DME-1483257 Phospholipid metabolism XP_046684305.1 P13706 R-DME-556833 Metabolism of lipids XP_046659737.1 Q02748 R-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression XP_046659737.1 Q02748 R-DME-392499 Metabolism of proteins XP_046659737.1 Q02748 R-DME-429914 Deadenylation-dependent mRNA decay XP_046659737.1 Q02748 R-DME-429947 Deadenylation of mRNA XP_046659737.1 Q02748 R-DME-72613 Eukaryotic Translation Initiation XP_046659737.1 Q02748 R-DME-72649 Translation initiation complex formation XP_046659737.1 Q02748 R-DME-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S XP_046659737.1 Q02748 R-DME-72702 Ribosomal scanning and start codon recognition XP_046659737.1 Q02748 R-DME-72737 Cap-dependent Translation Initiation XP_046659737.1 Q02748 R-DME-72766 Translation XP_046659737.1 Q02748 R-DME-8953854 Metabolism of RNA XP_046672077.1 Q9VMJ6 R-DME-168249 Innate Immune System XP_046672077.1 Q9VMJ6 R-DME-168256 Immune System XP_046672077.1 Q9VMJ6 R-DME-6798695 Neutrophil degranulation XP_046676990.1 Q9VMI3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046676990.1 Q9VMI3 R-DME-1430728 Metabolism XP_046676990.1 Q9VMI3 R-DME-392499 Metabolism of proteins XP_046676990.1 Q9VMI3 R-DME-611105 Respiratory electron transport XP_046676990.1 Q9VMI3 R-DME-6799198 Complex I biogenesis XP_046676990.1 Q9VMI3 R-DME-9837999 Mitochondrial protein degradation XP_046679405.1 Q9VMB9 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046679405.1 Q9VMB9 R-DME-1430728 Metabolism XP_046679405.1 Q9VMB9 R-DME-212436 Generic Transcription Pathway XP_046679405.1 Q9VMB9 R-DME-2262752 Cellular responses to stress XP_046679405.1 Q9VMB9 R-DME-3700989 Transcriptional Regulation by TP53 XP_046679405.1 Q9VMB9 R-DME-392499 Metabolism of proteins XP_046679405.1 Q9VMB9 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046679405.1 Q9VMB9 R-DME-611105 Respiratory electron transport XP_046679405.1 Q9VMB9 R-DME-73857 RNA Polymerase II Transcription XP_046679405.1 Q9VMB9 R-DME-74160 Gene expression (Transcription) XP_046679405.1 Q9VMB9 R-DME-8953897 Cellular responses to stimuli XP_046679405.1 Q9VMB9 R-DME-9707564 Cytoprotection by HMOX1 XP_046679405.1 Q9VMB9 R-DME-9711123 Cellular response to chemical stress XP_046679405.1 Q9VMB9 R-DME-9837999 Mitochondrial protein degradation XP_046679405.1 Q9VMB9 R-DME-9864848 Complex IV assembly XP_046669809.1 Q9V3N1 R-DME-109582 Hemostasis XP_046669809.1 Q9V3N1 R-DME-114608 Platelet degranulation XP_046669809.1 Q9V3N1 R-DME-1474244 Extracellular matrix organization XP_046669809.1 Q9V3N1 R-DME-1474290 Collagen formation XP_046669809.1 Q9V3N1 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046669809.1 Q9V3N1 R-DME-168249 Innate Immune System XP_046669809.1 Q9V3N1 R-DME-168256 Immune System XP_046669809.1 Q9V3N1 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046669809.1 Q9V3N1 R-DME-209449 Toll pathway XP_046669809.1 Q9V3N1 R-DME-212436 Generic Transcription Pathway XP_046669809.1 Q9V3N1 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046669809.1 Q9V3N1 R-DME-392499 Metabolism of proteins XP_046669809.1 Q9V3N1 R-DME-5252538 Drosophila signaling pathways XP_046669809.1 Q9V3N1 R-DME-597592 Post-translational protein modification XP_046669809.1 Q9V3N1 R-DME-6798695 Neutrophil degranulation XP_046669809.1 Q9V3N1 R-DME-73857 RNA Polymerase II Transcription XP_046669809.1 Q9V3N1 R-DME-74160 Gene expression (Transcription) XP_046669809.1 Q9V3N1 R-DME-76002 Platelet activation, signaling and aggregation XP_046669809.1 Q9V3N1 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046669809.1 Q9V3N1 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046669809.1 Q9V3N1 R-DME-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes XP_046669809.1 Q9V3N1 R-DME-8957275 Post-translational protein phosphorylation XP_046669809.1 Q9V3N1 R-DME-9686114 Non-canonical inflammasome activation XP_046669809.1 Q9V3N1 R-DME-9855719 Regulation of FXIIa and plasma kallikrein activity XP_046669809.1 Q9V3N1 R-DME-9948001 CASP4 inflammasome assembly XP_046669809.1 Q9V3N1 R-DME-9970672 FXIIa activates plasma kallikrein-kinin system XP_046669383.1 Q9V3D2 R-DME-1430728 Metabolism XP_046669383.1 Q9V3D2 R-DME-189445 Metabolism of porphyrins XP_046669383.1 Q9V3D2 R-DME-189451 Heme biosynthesis XP_046665479.1 Q9VM64 R-DME-1266738 Developmental Biology XP_046665479.1 Q9VM64 R-DME-168249 Innate Immune System XP_046665479.1 Q9VM64 R-DME-168256 Immune System XP_046665479.1 Q9VM64 R-DME-209338 Assembly of the 'signalling complexes' XP_046665479.1 Q9VM64 R-DME-209392 Hedgehog pathway XP_046665479.1 Q9VM64 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046665479.1 Q9VM64 R-DME-373760 L1CAM interactions XP_046665479.1 Q9VM64 R-DME-422475 Axon guidance XP_046665479.1 Q9VM64 R-DME-447043 Neurofascin interactions XP_046665479.1 Q9VM64 R-DME-5252538 Drosophila signaling pathways XP_046665479.1 Q9VM64 R-DME-6798695 Neutrophil degranulation XP_046665479.1 Q9VM64 R-DME-9675108 Nervous system development XP_046675321.1 Q9VM26 R-DME-162582 Signal Transduction XP_046675321.1 Q9VM26 R-DME-195721 Signaling by WNT XP_046675321.1 Q9VM26 R-DME-3238698 WNT ligand biogenesis and trafficking XP_046671589.1 P23696 R-DME-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 XP_046671589.1 P23696 R-DME-113510 E2F mediated regulation of DNA replication XP_046671589.1 P23696 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046671589.1 P23696 R-DME-1257604 PIP3 activates AKT signaling XP_046671589.1 P23696 R-DME-1280215 Cytokine Signaling in Immune system XP_046671589.1 P23696 R-DME-1280218 Adaptive Immune System XP_046671589.1 P23696 R-DME-1295596 Spry regulation of FGF signaling XP_046671589.1 P23696 R-DME-162582 Signal Transduction XP_046671589.1 P23696 R-DME-1640170 Cell Cycle XP_046671589.1 P23696 R-DME-168256 Immune System XP_046671589.1 P23696 R-DME-190236 Signaling by FGFR XP_046671589.1 P23696 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046671589.1 P23696 R-DME-195721 Signaling by WNT XP_046671589.1 P23696 R-DME-196299 Beta-catenin phosphorylation cascade XP_046671589.1 P23696 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046671589.1 P23696 R-DME-209155 Phosphorylation of AXN and APC XP_046671589.1 P23696 R-DME-209159 Assembly of the CI containing complexes XP_046671589.1 P23696 R-DME-209190 Phosphorylation of CI XP_046671589.1 P23696 R-DME-209214 Phosphorylation of SMO XP_046671589.1 P23696 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046671589.1 P23696 R-DME-209392 Hedgehog pathway XP_046671589.1 P23696 R-DME-209396 Phosphorylation of ARM XP_046671589.1 P23696 R-DME-209412 Wingless pathway XP_046671589.1 P23696 R-DME-209413 Assembly of the 'destruction complex' XP_046671589.1 P23696 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046671589.1 P23696 R-DME-209441 WG ligand not bound to FZ receptors XP_046671589.1 P23696 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046671589.1 P23696 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046671589.1 P23696 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046671589.1 P23696 R-DME-209469 WG ligand bound to FZ receptors XP_046671589.1 P23696 R-DME-216217 Activation of SMO XP_046671589.1 P23696 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046671589.1 P23696 R-DME-2995383 Initiation of Nuclear Envelope (NE) Reformation XP_046671589.1 P23696 R-DME-2995410 Nuclear Envelope (NE) Reassembly XP_046671589.1 P23696 R-DME-388841 Regulation of T cell activation by CD28 family XP_046671589.1 P23696 R-DME-389513 Co-inhibition by CTLA4 XP_046671589.1 P23696 R-DME-432553 Phosphorylation of PER and TIM XP_046671589.1 P23696 R-DME-432620 Dephosphorylation of PER XP_046671589.1 P23696 R-DME-432626 Circadian Clock pathway XP_046671589.1 P23696 R-DME-453274 Mitotic G2-G2/M phases XP_046671589.1 P23696 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046671589.1 P23696 R-DME-5252538 Drosophila signaling pathways XP_046671589.1 P23696 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046671589.1 P23696 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046671589.1 P23696 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046671589.1 P23696 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046671589.1 P23696 R-DME-5654736 Signaling by FGFR1 XP_046671589.1 P23696 R-DME-5654738 Signaling by FGFR2 XP_046671589.1 P23696 R-DME-5654741 Signaling by FGFR3 XP_046671589.1 P23696 R-DME-5654743 Signaling by FGFR4 XP_046671589.1 P23696 R-DME-5673000 RAF activation XP_046671589.1 P23696 R-DME-5673001 RAF/MAP kinase cascade XP_046671589.1 P23696 R-DME-5675221 Negative regulation of MAPK pathway XP_046671589.1 P23696 R-DME-5683057 MAPK family signaling cascades XP_046671589.1 P23696 R-DME-5684996 MAPK1/MAPK3 signaling XP_046671589.1 P23696 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046671589.1 P23696 R-DME-68882 Mitotic Anaphase XP_046671589.1 P23696 R-DME-68886 M Phase XP_046671589.1 P23696 R-DME-69206 G1/S Transition XP_046671589.1 P23696 R-DME-69231 Cyclin D associated events in G1 XP_046671589.1 P23696 R-DME-69236 G1 Phase XP_046671589.1 P23696 R-DME-69273 Cyclin A/B1/B2 associated events during G2/M transition XP_046671589.1 P23696 R-DME-69275 G2/M Transition XP_046671589.1 P23696 R-DME-69278 Cell Cycle, Mitotic XP_046671589.1 P23696 R-DME-8953854 Metabolism of RNA XP_046671589.1 P23696 R-DME-8953897 Cellular responses to stimuli XP_046671589.1 P23696 R-DME-9006925 Intracellular signaling by second messengers XP_046671589.1 P23696 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046671589.1 P23696 R-DME-913531 Interferon Signaling XP_046671589.1 P23696 R-DME-927802 Nonsense-Mediated Decay (NMD) XP_046671589.1 P23696 R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) XP_046671589.1 P23696 R-DME-9833482 PKR-mediated signaling XP_046671589.1 P23696 R-DME-9855142 Cellular responses to mechanical stimuli XP_046671589.1 P23696 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046671589.1 P23696 R-DME-9860931 Response of endothelial cells to shear stress XP_046664068.1 Q9VLT9 R-DME-209397 Formation of the cytosolic BSK 'scaffolding complex' XP_046664068.1 Q9VLT9 R-DME-209409 Formation of the nuclear AP-1 transcription factor 'scaffolding complex' XP_046664068.1 Q9VLT9 R-DME-209425 Transcriptional activtion by AP-1 transcription factor XP_046664068.1 Q9VLT9 R-DME-209459 Imd pathway XP_046664068.1 Q9VLT9 R-DME-350431 Planar Cell Polarity pathway XP_046664068.1 Q9VLT9 R-DME-450724 JNK signalling XP_046664068.1 Q9VLT9 R-DME-450736 Activation of Downstream Effectors XP_046664068.1 Q9VLT9 R-DME-5252538 Drosophila signaling pathways XP_046664068.1 D3DML3 R-DME-162582 Signal Transduction XP_046664068.1 D3DML3 R-DME-8939211 ESR-mediated signaling XP_046664068.1 D3DML3 R-DME-9006931 Signaling by Nuclear Receptors XP_046664068.1 D3DML3 R-DME-9009391 Extra-nuclear estrogen signaling XP_046671703.1 O18640 R-DME-162582 Signal Transduction XP_046671703.1 O18640 R-DME-5357905 Regulation of TNFR1 signaling XP_046671703.1 O18640 R-DME-73887 Death Receptor Signaling XP_046671703.1 O18640 R-DME-75893 TNF signaling XP_046672061.1 Q8SY53 R-DME-168249 Innate Immune System XP_046672061.1 Q8SY53 R-DME-168256 Immune System XP_046672061.1 Q8SY53 R-DME-382551 Transport of small molecules XP_046672061.1 Q8SY53 R-DME-5223345 Miscellaneous transport and binding events XP_046672061.1 Q8SY53 R-DME-6798695 Neutrophil degranulation XP_046666076.1 E1JHB7 R-DME-109704 PI3K Cascade XP_046666076.1 E1JHB7 R-DME-112399 IRS-mediated signalling XP_046666076.1 E1JHB7 R-DME-1257604 PIP3 activates AKT signaling XP_046666076.1 E1JHB7 R-DME-1280215 Cytokine Signaling in Immune system XP_046666076.1 E1JHB7 R-DME-1433557 Signaling by SCF-KIT XP_046666076.1 E1JHB7 R-DME-1433559 Regulation of KIT signaling XP_046666076.1 E1JHB7 R-DME-1474244 Extracellular matrix organization XP_046666076.1 E1JHB7 R-DME-162582 Signal Transduction XP_046666076.1 E1JHB7 R-DME-168256 Immune System XP_046666076.1 E1JHB7 R-DME-186763 Downstream signal transduction XP_046666076.1 E1JHB7 R-DME-186797 Signaling by PDGF XP_046666076.1 E1JHB7 R-DME-194138 Signaling by VEGF XP_046666076.1 E1JHB7 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046666076.1 E1JHB7 R-DME-216083 Integrin cell surface interactions XP_046666076.1 E1JHB7 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046666076.1 E1JHB7 R-DME-2428924 IGF1R signaling cascade XP_046666076.1 E1JHB7 R-DME-2428928 IRS-related events triggered by IGF1R XP_046666076.1 E1JHB7 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046666076.1 E1JHB7 R-DME-5673001 RAF/MAP kinase cascade XP_046666076.1 E1JHB7 R-DME-5683057 MAPK family signaling cascades XP_046666076.1 E1JHB7 R-DME-5684996 MAPK1/MAPK3 signaling XP_046666076.1 E1JHB7 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046666076.1 E1JHB7 R-DME-74751 Insulin receptor signalling cascade XP_046666076.1 E1JHB7 R-DME-74752 Signaling by Insulin receptor XP_046666076.1 E1JHB7 R-DME-9006925 Intracellular signaling by second messengers XP_046666076.1 E1JHB7 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046666076.1 E1JHB7 R-DME-9607240 FLT3 Signaling XP_046673662.1 Q9VLJ8 R-DME-1430728 Metabolism XP_046673662.1 Q9VLJ8 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046673662.1 Q9VLJ8 R-DME-196854 Metabolism of vitamins and cofactors XP_046673662.1 Q9VLJ8 R-DME-947581 Molybdenum cofactor biosynthesis XP_046664917.1 Q9VLL5 R-DME-1430728 Metabolism XP_046664917.1 Q9VLL5 R-DME-1630316 Glycosaminoglycan metabolism XP_046664917.1 Q9VLL5 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046664917.1 Q9VLL5 R-DME-2024096 HS-GAG degradation XP_046664917.1 Q9VLL5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046676975.1 M9PCZ7 R-DME-162582 Signal Transduction XP_046676975.1 M9PCZ7 R-DME-195721 Signaling by WNT XP_046676975.1 M9PCZ7 R-DME-201681 TCF dependent signaling in response to WNT XP_046676975.1 M9PCZ7 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046679003.1 Q7K237 R-DME-392499 Metabolism of proteins XP_046679003.1 Q7K237 R-DME-5173105 O-linked glycosylation XP_046679003.1 Q7K237 R-DME-597592 Post-translational protein modification XP_046679003.1 Q7K237 R-DME-913709 O-linked glycosylation of mucins XP_046679369.1 Q9VLA1 R-DME-1430728 Metabolism XP_046679369.1 Q9VLA1 R-DME-1630316 Glycosaminoglycan metabolism XP_046679369.1 Q9VLA1 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046679369.1 Q9VLA1 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046668204.1 P12370 R-DME-109582 Hemostasis XP_046668204.1 P12370 R-DME-111885 Opioid Signalling XP_046668204.1 P12370 R-DME-111931 PKA-mediated phosphorylation of CREB XP_046668204.1 P12370 R-DME-111933 Calmodulin induced events XP_046668204.1 P12370 R-DME-111996 Ca-dependent events XP_046668204.1 P12370 R-DME-111997 CaM pathway XP_046668204.1 P12370 R-DME-112040 G-protein mediated events XP_046668204.1 P12370 R-DME-112043 PLC beta mediated events XP_046668204.1 P12370 R-DME-112314 Neurotransmitter receptors and postsynaptic signal transmission XP_046668204.1 P12370 R-DME-112315 Transmission across Chemical Synapses XP_046668204.1 P12370 R-DME-112316 Neuronal System XP_046668204.1 P12370 R-DME-1280218 Adaptive Immune System XP_046668204.1 P12370 R-DME-1430728 Metabolism XP_046668204.1 P12370 R-DME-1489509 DAG and IP3 signaling XP_046668204.1 P12370 R-DME-162582 Signal Transduction XP_046668204.1 P12370 R-DME-163359 Glucagon signaling in metabolic regulation XP_046668204.1 P12370 R-DME-163615 PKA activation XP_046668204.1 P12370 R-DME-163685 Integration of energy metabolism XP_046668204.1 P12370 R-DME-164378 PKA activation in glucagon signalling XP_046668204.1 P12370 R-DME-168249 Innate Immune System XP_046668204.1 P12370 R-DME-168256 Immune System XP_046668204.1 P12370 R-DME-180024 DARPP-32 events XP_046668204.1 P12370 R-DME-209159 Assembly of the CI containing complexes XP_046668204.1 P12370 R-DME-209190 Phosphorylation of CI XP_046668204.1 P12370 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046668204.1 P12370 R-DME-209392 Hedgehog pathway XP_046668204.1 P12370 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046668204.1 P12370 R-DME-372790 Signaling by GPCR XP_046668204.1 P12370 R-DME-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion XP_046668204.1 P12370 R-DME-382551 Transport of small molecules XP_046668204.1 P12370 R-DME-388396 GPCR downstream signalling XP_046668204.1 P12370 R-DME-392499 Metabolism of proteins XP_046668204.1 P12370 R-DME-392517 Rap1 signalling XP_046668204.1 P12370 R-DME-397014 Muscle contraction XP_046668204.1 P12370 R-DME-418555 G alpha (s) signalling events XP_046668204.1 P12370 R-DME-418594 G alpha (i) signalling events XP_046668204.1 P12370 R-DME-422356 Regulation of insulin secretion XP_046668204.1 P12370 R-DME-432040 Vasopressin regulates renal water homeostasis via Aquaporins XP_046668204.1 P12370 R-DME-438064 Post NMDA receptor activation events XP_046668204.1 P12370 R-DME-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase XP_046668204.1 P12370 R-DME-442755 Activation of NMDA receptors and postsynaptic events XP_046668204.1 P12370 R-DME-445717 Aquaporin-mediated transport XP_046668204.1 P12370 R-DME-5252538 Drosophila signaling pathways XP_046668204.1 P12370 R-DME-5358351 Signaling by Hedgehog XP_046668204.1 P12370 R-DME-5576891 Cardiac conduction XP_046668204.1 P12370 R-DME-5578775 Ion homeostasis XP_046668204.1 P12370 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046668204.1 P12370 R-DME-5610787 Hedgehog 'off' state XP_046668204.1 P12370 R-DME-5621481 C-type lectin receptors (CLRs) XP_046668204.1 P12370 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046668204.1 P12370 R-DME-8953897 Cellular responses to stimuli XP_046668204.1 P12370 R-DME-9006925 Intracellular signaling by second messengers XP_046668204.1 P12370 R-DME-9634597 GPER1 signaling XP_046668204.1 P12370 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046668204.1 P12370 R-DME-9837999 Mitochondrial protein degradation XP_046668204.1 P12370 R-DME-9855142 Cellular responses to mechanical stimuli XP_046668204.1 P12370 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046668204.1 P12370 R-DME-9860931 Response of endothelial cells to shear stress XP_046663607.1 Q9VL00 R-DME-392499 Metabolism of proteins XP_046663607.1 Q9VL00 R-DME-5688426 Deubiquitination XP_046663607.1 Q9VL00 R-DME-5689880 Ub-specific processing proteases XP_046663607.1 Q9VL00 R-DME-5689896 Ovarian tumor domain proteases XP_046663607.1 Q9VL00 R-DME-597592 Post-translational protein modification XP_046679904.1 Q9VKZ1 R-DME-1430728 Metabolism XP_046679904.1 Q9VKZ1 R-DME-189445 Metabolism of porphyrins XP_046679904.1 Q9VKZ1 R-DME-189451 Heme biosynthesis XP_046670798.1 Q9VKX7 R-DME-392499 Metabolism of proteins XP_046670798.1 Q9VKX7 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046670798.1 Q9VKX7 R-DME-446203 Asparagine N-linked glycosylation XP_046670798.1 Q9VKX7 R-DME-597592 Post-translational protein modification XP_046676425.1 Q8IPC5 R-DME-162582 Signal Transduction XP_046676425.1 Q8IPC5 R-DME-392499 Metabolism of proteins XP_046676425.1 Q8IPC5 R-DME-5357905 Regulation of TNFR1 signaling XP_046676425.1 Q8IPC5 R-DME-5688426 Deubiquitination XP_046676425.1 Q8IPC5 R-DME-5689880 Ub-specific processing proteases XP_046676425.1 Q8IPC5 R-DME-597592 Post-translational protein modification XP_046676425.1 Q8IPC5 R-DME-73887 Death Receptor Signaling XP_046676425.1 Q8IPC5 R-DME-75893 TNF signaling XP_046672821.1 P92208 R-DME-1280215 Cytokine Signaling in Immune system XP_046672821.1 P92208 R-DME-162582 Signal Transduction XP_046672821.1 P92208 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046672821.1 P92208 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046672821.1 P92208 R-DME-166166 MyD88-independent TLR4 cascade XP_046672821.1 P92208 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046672821.1 P92208 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046672821.1 P92208 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046672821.1 P92208 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046672821.1 P92208 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046672821.1 P92208 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046672821.1 P92208 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046672821.1 P92208 R-DME-168249 Innate Immune System XP_046672821.1 P92208 R-DME-168256 Immune System XP_046672821.1 P92208 R-DME-168898 Toll-like Receptor Cascades XP_046672821.1 P92208 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046672821.1 P92208 R-DME-193648 NRAGE signals death through JNK XP_046672821.1 P92208 R-DME-193704 p75 NTR receptor-mediated signalling XP_046672821.1 P92208 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046672821.1 P92208 R-DME-209397 Formation of the cytosolic BSK 'scaffolding complex' XP_046672821.1 P92208 R-DME-209409 Formation of the nuclear AP-1 transcription factor 'scaffolding complex' XP_046672821.1 P92208 R-DME-209425 Transcriptional activtion by AP-1 transcription factor XP_046672821.1 P92208 R-DME-209459 Imd pathway XP_046672821.1 P92208 R-DME-2262752 Cellular responses to stress XP_046672821.1 P92208 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046672821.1 P92208 R-DME-2559580 Oxidative Stress Induced Senescence XP_046672821.1 P92208 R-DME-2559583 Cellular Senescence XP_046672821.1 P92208 R-DME-2871796 FCERI mediated MAPK activation XP_046672821.1 P92208 R-DME-350431 Planar Cell Polarity pathway XP_046672821.1 P92208 R-DME-446652 Interleukin-1 family signaling XP_046672821.1 P92208 R-DME-448424 Interleukin-17 signaling XP_046672821.1 P92208 R-DME-449147 Signaling by Interleukins XP_046672821.1 P92208 R-DME-450282 MAPK targets/ Nuclear events mediated by MAP kinases XP_046672821.1 P92208 R-DME-450294 MAP kinase activation XP_046672821.1 P92208 R-DME-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 XP_046672821.1 P92208 R-DME-450341 Activation of the AP-1 family of transcription factors XP_046672821.1 P92208 R-DME-450724 JNK signalling XP_046672821.1 P92208 R-DME-450736 Activation of Downstream Effectors XP_046672821.1 P92208 R-DME-5252538 Drosophila signaling pathways XP_046672821.1 P92208 R-DME-73887 Death Receptor Signaling XP_046672821.1 P92208 R-DME-8953897 Cellular responses to stimuli XP_046672821.1 P92208 R-DME-9007892 Interleukin-38 signaling XP_046672821.1 P92208 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046672821.1 P92208 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046672821.1 P92208 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046672821.1 P92208 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046674467.1 Q9XTN2 R-DME-109704 PI3K Cascade XP_046674467.1 Q9XTN2 R-DME-110478 Insulin signaling pathway XP_046674467.1 Q9XTN2 R-DME-110526 Insulin receptor mediated signaling XP_046674467.1 Q9XTN2 R-DME-112399 IRS-mediated signalling XP_046674467.1 Q9XTN2 R-DME-112412 SOS-mediated signalling XP_046674467.1 Q9XTN2 R-DME-1257604 PIP3 activates AKT signaling XP_046674467.1 Q9XTN2 R-DME-162582 Signal Transduction XP_046674467.1 Q9XTN2 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046674467.1 Q9XTN2 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046674467.1 Q9XTN2 R-DME-2428924 IGF1R signaling cascade XP_046674467.1 Q9XTN2 R-DME-2428928 IRS-related events triggered by IGF1R XP_046674467.1 Q9XTN2 R-DME-5252538 Drosophila signaling pathways XP_046674467.1 Q9XTN2 R-DME-5673001 RAF/MAP kinase cascade XP_046674467.1 Q9XTN2 R-DME-5683057 MAPK family signaling cascades XP_046674467.1 Q9XTN2 R-DME-5684996 MAPK1/MAPK3 signaling XP_046674467.1 Q9XTN2 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046674467.1 Q9XTN2 R-DME-74749 Signal attenuation XP_046674467.1 Q9XTN2 R-DME-74751 Insulin receptor signalling cascade XP_046674467.1 Q9XTN2 R-DME-74752 Signaling by Insulin receptor XP_046674467.1 Q9XTN2 R-DME-9006925 Intracellular signaling by second messengers XP_046674467.1 Q9XTN2 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046688540.1 Q9VKM3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046688540.1 Q9VKM3 R-DME-1430728 Metabolism XP_046688540.1 Q9VKM3 R-DME-1592230 Mitochondrial biogenesis XP_046688540.1 Q9VKM3 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046688540.1 Q9VKM3 R-DME-1852241 Organelle biogenesis and maintenance XP_046688540.1 Q9VKM3 R-DME-392499 Metabolism of proteins XP_046688540.1 Q9VKM3 R-DME-8949613 Cristae formation XP_046688540.1 Q9VKM3 R-DME-9837999 Mitochondrial protein degradation XP_046658868.1 Q9VKJ8 R-DME-1430728 Metabolism XP_046658868.1 Q9VKJ8 R-DME-1630316 Glycosaminoglycan metabolism XP_046658868.1 Q9VKJ8 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046658868.1 Q9VKJ8 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046658868.1 Q9VKJ8 R-DME-2024096 HS-GAG degradation XP_046658868.1 Q9VKJ8 R-DME-2024101 CS/DS degradation XP_046658868.1 Q9VKJ8 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046672367.1 Q9VKG8 R-DME-162582 Signal Transduction XP_046672367.1 Q9VKG8 R-DME-194315 Signaling by Rho GTPases XP_046672367.1 Q9VKG8 R-DME-9012999 RHO GTPase cycle XP_046672367.1 Q9VKG8 R-DME-9013420 RHOU GTPase cycle XP_046672367.1 Q9VKG8 R-DME-9013424 RHOV GTPase cycle XP_046672367.1 Q9VKG8 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046676049.1 Q9VKD3 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046676049.1 Q9VKD3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046676049.1 Q9VKD3 R-DME-1430728 Metabolism XP_046676049.1 Q9VKD3 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046676049.1 Q9VKD3 R-DME-196854 Metabolism of vitamins and cofactors XP_046676049.1 Q9VKD3 R-DME-611105 Respiratory electron transport XP_046676049.1 Q9VKD3 R-DME-947581 Molybdenum cofactor biosynthesis XP_046676049.1 Q9VKD3 R-DME-9865881 Complex III assembly XP_046664199.1 Q9VKB2 R-DME-1500931 Cell-Cell communication XP_046664199.1 Q9VKB2 R-DME-162582 Signal Transduction XP_046664199.1 Q9VKB2 R-DME-418990 Adherens junctions interactions XP_046664199.1 Q9VKB2 R-DME-421270 Cell-cell junction organization XP_046664199.1 Q9VKB2 R-DME-446728 Cell junction organization XP_046664199.1 Q9VKB2 R-DME-8848021 Signaling by PTK6 XP_046664199.1 Q9VKB2 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046664199.1 Q9VKB2 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046664199.1 Q9VKB2 R-DME-9958810 SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) XP_046664199.1 Q9VKB2 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046664750.1 M9PD12 R-DME-382551 Transport of small molecules XP_046664750.1 M9PD12 R-DME-5223345 Miscellaneous transport and binding events XP_046673555.1 Q9VK45 R-DME-1257604 PIP3 activates AKT signaling XP_046673555.1 Q9VK45 R-DME-1280218 Adaptive Immune System XP_046673555.1 Q9VK45 R-DME-162582 Signal Transduction XP_046673555.1 Q9VK45 R-DME-1632852 Macroautophagy XP_046673555.1 Q9VK45 R-DME-165159 MTOR signalling XP_046673555.1 Q9VK45 R-DME-166208 mTORC1-mediated signalling XP_046673555.1 Q9VK45 R-DME-168256 Immune System XP_046673555.1 Q9VK45 R-DME-194138 Signaling by VEGF XP_046673555.1 Q9VK45 R-DME-212436 Generic Transcription Pathway XP_046673555.1 Q9VK45 R-DME-2262752 Cellular responses to stress XP_046673555.1 Q9VK45 R-DME-3371556 Cellular response to heat stress XP_046673555.1 Q9VK45 R-DME-3371571 HSF1-dependent transactivation XP_046673555.1 Q9VK45 R-DME-3700989 Transcriptional Regulation by TP53 XP_046673555.1 Q9VK45 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046673555.1 Q9VK45 R-DME-388841 Regulation of T cell activation by CD28 family XP_046673555.1 Q9VK45 R-DME-389356 Co-stimulation by CD28 XP_046673555.1 Q9VK45 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046673555.1 Q9VK45 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046673555.1 Q9VK45 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046673555.1 Q9VK45 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046673555.1 Q9VK45 R-DME-6807070 PTEN Regulation XP_046673555.1 Q9VK45 R-DME-73857 RNA Polymerase II Transcription XP_046673555.1 Q9VK45 R-DME-74160 Gene expression (Transcription) XP_046673555.1 Q9VK45 R-DME-8943724 Regulation of PTEN gene transcription XP_046673555.1 Q9VK45 R-DME-8953897 Cellular responses to stimuli XP_046673555.1 Q9VK45 R-DME-9006925 Intracellular signaling by second messengers XP_046673555.1 Q9VK45 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046673555.1 Q9VK45 R-DME-9612973 Autophagy XP_046673555.1 Q9VK45 R-DME-9639288 Amino acids regulate mTORC1 XP_046673555.1 Q9VK45 R-DME-9711097 Cellular response to starvation XP_046673555.1 Q9VK45 R-DME-9855142 Cellular responses to mechanical stimuli XP_046673555.1 Q9VK45 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046673555.1 Q9VK45 R-DME-9860931 Response of endothelial cells to shear stress XP_046673555.1 Q8T9I6 R-DME-110523 TOR signaling pathway XP_046673555.1 Q8T9I6 R-DME-110526 Insulin receptor mediated signaling XP_046673555.1 Q8T9I6 R-DME-5252538 Drosophila signaling pathways XP_046668552.1 Q9VK34 R-DME-1266738 Developmental Biology XP_046668552.1 Q9VK34 R-DME-212165 Epigenetic regulation of gene expression XP_046668552.1 Q9VK34 R-DME-212436 Generic Transcription Pathway XP_046668552.1 Q9VK34 R-DME-427359 SIRT1 negatively regulates rRNA expression XP_046668552.1 Q9VK34 R-DME-5250941 Negative epigenetic regulation of rRNA expression XP_046668552.1 Q9VK34 R-DME-73857 RNA Polymerase II Transcription XP_046668552.1 Q9VK34 R-DME-74160 Gene expression (Transcription) XP_046668552.1 Q9VK34 R-DME-9614085 FOXO-mediated transcription XP_046668552.1 Q9VK34 R-DME-9617629 Regulation of FOXO transcriptional activity by acetylation XP_046668552.1 Q9VK34 R-DME-9730414 MITF-M-regulated melanocyte development XP_046668552.1 Q9VK34 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046668552.1 Q9VK34 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046668552.1 Q9VK34 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046668552.1 Q9VK34 R-DME-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity XP_046668552.1 Q9VK34 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046675744.1 Q9VK07 R-DME-1632852 Macroautophagy XP_046675744.1 Q9VK07 R-DME-9612973 Autophagy XP_046682100.1 Q9VJZ4 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682100.1 Q9VJZ4 R-DME-1430728 Metabolism XP_046682100.1 Q9VJZ4 R-DME-611105 Respiratory electron transport XP_046682100.1 Q9VJZ4 R-DME-6799198 Complex I biogenesis XP_046662173.1 O61443 R-DME-109582 Hemostasis XP_046662173.1 O61443 R-DME-1266738 Developmental Biology XP_046662173.1 O61443 R-DME-1280215 Cytokine Signaling in Immune system XP_046662173.1 O61443 R-DME-162582 Signal Transduction XP_046662173.1 O61443 R-DME-1640170 Cell Cycle XP_046662173.1 O61443 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046662173.1 O61443 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046662173.1 O61443 R-DME-166166 MyD88-independent TLR4 cascade XP_046662173.1 O61443 R-DME-166520 Signaling by NTRKs XP_046662173.1 O61443 R-DME-167044 Signalling to RAS XP_046662173.1 O61443 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046662173.1 O61443 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046662173.1 O61443 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046662173.1 O61443 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046662173.1 O61443 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046662173.1 O61443 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046662173.1 O61443 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046662173.1 O61443 R-DME-168249 Innate Immune System XP_046662173.1 O61443 R-DME-168256 Immune System XP_046662173.1 O61443 R-DME-168638 NOD1/2 Signaling Pathway XP_046662173.1 O61443 R-DME-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways XP_046662173.1 O61443 R-DME-168898 Toll-like Receptor Cascades XP_046662173.1 O61443 R-DME-171007 p38MAPK events XP_046662173.1 O61443 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046662173.1 O61443 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046662173.1 O61443 R-DME-187687 Signalling to ERKs XP_046662173.1 O61443 R-DME-194138 Signaling by VEGF XP_046662173.1 O61443 R-DME-198725 Nuclear Events (kinase and transcription factor activation) XP_046662173.1 O61443 R-DME-198753 ERK/MAPK targets XP_046662173.1 O61443 R-DME-2262752 Cellular responses to stress XP_046662173.1 O61443 R-DME-2559580 Oxidative Stress Induced Senescence XP_046662173.1 O61443 R-DME-2559583 Cellular Senescence XP_046662173.1 O61443 R-DME-392518 Signal amplification XP_046662173.1 O61443 R-DME-418592 ADP signalling through P2Y purinoceptor 1 XP_046662173.1 O61443 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046662173.1 O61443 R-DME-448424 Interleukin-17 signaling XP_046662173.1 O61443 R-DME-449147 Signaling by Interleukins XP_046662173.1 O61443 R-DME-450282 MAPK targets/ Nuclear events mediated by MAP kinases XP_046662173.1 O61443 R-DME-450294 MAP kinase activation XP_046662173.1 O61443 R-DME-450302 activated TAK1 mediates p38 MAPK activation XP_046662173.1 O61443 R-DME-450341 Activation of the AP-1 family of transcription factors XP_046662173.1 O61443 R-DME-525793 Myogenesis XP_046662173.1 O61443 R-DME-5673001 RAF/MAP kinase cascade XP_046662173.1 O61443 R-DME-5675221 Negative regulation of MAPK pathway XP_046662173.1 O61443 R-DME-5683057 MAPK family signaling cascades XP_046662173.1 O61443 R-DME-5684996 MAPK1/MAPK3 signaling XP_046662173.1 O61443 R-DME-6798695 Neutrophil degranulation XP_046662173.1 O61443 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046662173.1 O61443 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046662173.1 O61443 R-DME-69615 G1/S DNA Damage Checkpoints XP_046662173.1 O61443 R-DME-69620 Cell Cycle Checkpoints XP_046662173.1 O61443 R-DME-76002 Platelet activation, signaling and aggregation XP_046662173.1 O61443 R-DME-8953897 Cellular responses to stimuli XP_046662173.1 O61443 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046662173.1 O61443 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046662173.1 O61443 R-DME-9730414 MITF-M-regulated melanocyte development XP_046662173.1 O61443 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046662173.1 O61443 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046662173.1 O61443 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046662173.1 O61443 R-DME-9824585 Regulation of MITF-M-dependent genes involved in pigmentation XP_046662173.1 O61443 R-DME-9856651 MITF-M-dependent gene expression XP_046683339.1 P26675 R-DME-109582 Hemostasis XP_046683339.1 P26675 R-DME-112399 IRS-mediated signalling XP_046683339.1 P26675 R-DME-112412 SOS-mediated signalling XP_046683339.1 P26675 R-DME-1227986 Signaling by ERBB2 XP_046683339.1 P26675 R-DME-1236394 Signaling by ERBB4 XP_046683339.1 P26675 R-DME-1250347 SHC1 events in ERBB4 signaling XP_046683339.1 P26675 R-DME-1266738 Developmental Biology XP_046683339.1 P26675 R-DME-1280215 Cytokine Signaling in Immune system XP_046683339.1 P26675 R-DME-1433557 Signaling by SCF-KIT XP_046683339.1 P26675 R-DME-1433559 Regulation of KIT signaling XP_046683339.1 P26675 R-DME-162582 Signal Transduction XP_046683339.1 P26675 R-DME-166520 Signaling by NTRKs XP_046683339.1 P26675 R-DME-167044 Signalling to RAS XP_046683339.1 P26675 R-DME-168249 Innate Immune System XP_046683339.1 P26675 R-DME-168256 Immune System XP_046683339.1 P26675 R-DME-177929 Signaling by EGFR XP_046683339.1 P26675 R-DME-179812 GRB2 events in EGFR signaling XP_046683339.1 P26675 R-DME-180336 SHC1 events in EGFR signaling XP_046683339.1 P26675 R-DME-186763 Downstream signal transduction XP_046683339.1 P26675 R-DME-186797 Signaling by PDGF XP_046683339.1 P26675 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046683339.1 P26675 R-DME-187687 Signalling to ERKs XP_046683339.1 P26675 R-DME-190236 Signaling by FGFR XP_046683339.1 P26675 R-DME-193648 NRAGE signals death through JNK XP_046683339.1 P26675 R-DME-193704 p75 NTR receptor-mediated signalling XP_046683339.1 P26675 R-DME-194315 Signaling by Rho GTPases XP_046683339.1 P26675 R-DME-1963640 GRB2 events in ERBB2 signaling XP_046683339.1 P26675 R-DME-202733 Cell surface interactions at the vascular wall XP_046683339.1 P26675 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046683339.1 P26675 R-DME-210993 Tie2 Signaling XP_046683339.1 P26675 R-DME-2172127 DAP12 interactions XP_046683339.1 P26675 R-DME-2179392 EGFR Transactivation by Gastrin XP_046683339.1 P26675 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046683339.1 P26675 R-DME-2424491 DAP12 signaling XP_046683339.1 P26675 R-DME-2428924 IGF1R signaling cascade XP_046683339.1 P26675 R-DME-2428928 IRS-related events triggered by IGF1R XP_046683339.1 P26675 R-DME-2428933 SHC-related events triggered by IGF1R XP_046683339.1 P26675 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046683339.1 P26675 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046683339.1 P26675 R-DME-2871796 FCERI mediated MAPK activation XP_046683339.1 P26675 R-DME-2871809 FCERI mediated Ca+2 mobilization XP_046683339.1 P26675 R-DME-372790 Signaling by GPCR XP_046683339.1 P26675 R-DME-375165 NCAM signaling for neurite out-growth XP_046683339.1 P26675 R-DME-388396 GPCR downstream signalling XP_046683339.1 P26675 R-DME-416476 G alpha (q) signalling events XP_046683339.1 P26675 R-DME-416482 G alpha (12/13) signalling events XP_046683339.1 P26675 R-DME-422475 Axon guidance XP_046683339.1 P26675 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046683339.1 P26675 R-DME-5654688 SHC-mediated cascade:FGFR1 XP_046683339.1 P26675 R-DME-5654693 FRS-mediated FGFR1 signaling XP_046683339.1 P26675 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046683339.1 P26675 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046683339.1 P26675 R-DME-5654700 FRS-mediated FGFR2 signaling XP_046683339.1 P26675 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046683339.1 P26675 R-DME-5654706 FRS-mediated FGFR3 signaling XP_046683339.1 P26675 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046683339.1 P26675 R-DME-5654712 FRS-mediated FGFR4 signaling XP_046683339.1 P26675 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046683339.1 P26675 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046683339.1 P26675 R-DME-5654736 Signaling by FGFR1 XP_046683339.1 P26675 R-DME-5654738 Signaling by FGFR2 XP_046683339.1 P26675 R-DME-5654741 Signaling by FGFR3 XP_046683339.1 P26675 R-DME-5654743 Signaling by FGFR4 XP_046683339.1 P26675 R-DME-5673001 RAF/MAP kinase cascade XP_046683339.1 P26675 R-DME-5683057 MAPK family signaling cascades XP_046683339.1 P26675 R-DME-5684996 MAPK1/MAPK3 signaling XP_046683339.1 P26675 R-DME-73887 Death Receptor Signaling XP_046683339.1 P26675 R-DME-74749 Signal attenuation XP_046683339.1 P26675 R-DME-74751 Insulin receptor signalling cascade XP_046683339.1 P26675 R-DME-74752 Signaling by Insulin receptor XP_046683339.1 P26675 R-DME-881907 Gastrin-CREB signalling pathway via PKC and MAPK XP_046683339.1 P26675 R-DME-8853659 RET signaling XP_046683339.1 P26675 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046683339.1 P26675 R-DME-9012999 RHO GTPase cycle XP_046683339.1 P26675 R-DME-9013149 RAC1 GTPase cycle XP_046683339.1 P26675 R-DME-9607240 FLT3 Signaling XP_046683339.1 P26675 R-DME-9675108 Nervous system development XP_046683339.1 P26675 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046670097.1 Q8MVS5 R-DME-392499 Metabolism of proteins XP_046670097.1 Q8MVS5 R-DME-5173105 O-linked glycosylation XP_046670097.1 Q8MVS5 R-DME-597592 Post-translational protein modification XP_046670097.1 Q8MVS5 R-DME-913709 O-linked glycosylation of mucins XP_046676248.1 P28159 R-DME-212436 Generic Transcription Pathway XP_046676248.1 P28159 R-DME-350054 Notch-HLH transcription pathway XP_046676248.1 P28159 R-DME-73857 RNA Polymerase II Transcription XP_046676248.1 P28159 R-DME-74160 Gene expression (Transcription) XP_046663226.1 Q9VJN5 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046663226.1 Q9VJN5 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046663226.1 Q9VJN5 R-DME-209449 Toll pathway XP_046663226.1 Q9VJN5 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046663226.1 Q9VJN5 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046663226.1 Q9VJN5 R-DME-214862 Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' XP_046663226.1 Q9VJN5 R-DME-214863 Adaptor protein complex binds to TL receptor at the plasma membrane XP_046663226.1 Q9VJN5 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046663226.1 Q9VJN5 R-DME-214874 PLL kinase binds to TUB in the TL receptor 'signalling complex' XP_046663226.1 Q9VJN5 R-DME-5252538 Drosophila signaling pathways XP_046672801.1 Q7KT70 R-DME-112316 Neuronal System XP_046672801.1 Q7KT70 R-DME-6794361 Neurexins and neuroligins XP_046672801.1 Q7KT70 R-DME-6794362 Protein-protein interactions at synapses XP_046664094.1 Q9V3D0 R-DME-392499 Metabolism of proteins XP_046664094.1 Q9V3D0 R-DME-5368287 Mitochondrial translation XP_046664094.1 Q9V3D0 R-DME-5389840 Mitochondrial translation elongation XP_046664094.1 Q9V3D0 R-DME-5419276 Mitochondrial translation termination XP_046664094.1 Q9V3D0 R-DME-72766 Translation XP_046664094.1 Q9V3D0 R-DME-9937383 Mitochondrial ribosome-associated quality control XP_046663622.1 Q03017 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046663622.1 Q03017 R-DME-1169091 Activation of NF-kappaB in B cells XP_046663622.1 Q03017 R-DME-1280215 Cytokine Signaling in Immune system XP_046663622.1 Q03017 R-DME-1280218 Adaptive Immune System XP_046663622.1 Q03017 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046663622.1 Q03017 R-DME-162582 Signal Transduction XP_046663622.1 Q03017 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046663622.1 Q03017 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046663622.1 Q03017 R-DME-166166 MyD88-independent TLR4 cascade XP_046663622.1 Q03017 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046663622.1 Q03017 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046663622.1 Q03017 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046663622.1 Q03017 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046663622.1 Q03017 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046663622.1 Q03017 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046663622.1 Q03017 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046663622.1 Q03017 R-DME-168249 Innate Immune System XP_046663622.1 Q03017 R-DME-168256 Immune System XP_046663622.1 Q03017 R-DME-168898 Toll-like Receptor Cascades XP_046663622.1 Q03017 R-DME-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta XP_046663622.1 Q03017 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046663622.1 Q03017 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046663622.1 Q03017 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046663622.1 Q03017 R-DME-193639 p75NTR signals via NF-kB XP_046663622.1 Q03017 R-DME-193704 p75 NTR receptor-mediated signalling XP_046663622.1 Q03017 R-DME-202403 TCR signaling XP_046663622.1 Q03017 R-DME-202424 Downstream TCR signaling XP_046663622.1 Q03017 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046663622.1 Q03017 R-DME-209449 Toll pathway XP_046663622.1 Q03017 R-DME-209560 NF-kB is activated and signals survival XP_046663622.1 Q03017 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046663622.1 Q03017 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046663622.1 Q03017 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046663622.1 Q03017 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046663622.1 Q03017 R-DME-2871837 FCERI mediated NF-kB activation XP_046663622.1 Q03017 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046663622.1 Q03017 R-DME-446652 Interleukin-1 family signaling XP_046663622.1 Q03017 R-DME-449147 Signaling by Interleukins XP_046663622.1 Q03017 R-DME-5252538 Drosophila signaling pathways XP_046663622.1 Q03017 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046663622.1 Q03017 R-DME-5621481 C-type lectin receptors (CLRs) XP_046663622.1 Q03017 R-DME-73887 Death Receptor Signaling XP_046663622.1 Q03017 R-DME-8953897 Cellular responses to stimuli XP_046663622.1 Q03017 R-DME-9020702 Interleukin-1 signaling XP_046663622.1 Q03017 R-DME-933542 TRAF6 mediated NF-kB activation XP_046663622.1 Q03017 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046663622.1 Q03017 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046663622.1 Q03017 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046663622.1 Q03017 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046663622.1 Q03017 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046663622.1 Q03017 R-DME-9855142 Cellular responses to mechanical stimuli XP_046663622.1 Q03017 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046663622.1 Q03017 R-DME-9860931 Response of endothelial cells to shear stress XP_046672125.1 O61722 R-DME-392499 Metabolism of proteins XP_046672125.1 O61722 R-DME-597592 Post-translational protein modification XP_046672125.1 O61722 R-DME-8873719 RAB geranylgeranylation XP_046682182.1 Q9VJG5 R-DME-1430728 Metabolism XP_046682182.1 Q9VJG5 R-DME-1630316 Glycosaminoglycan metabolism XP_046682182.1 Q9VJG5 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046682182.1 Q9VJG5 R-DME-2022870 CS-GAG biosynthesis XP_046682182.1 Q9VJG5 R-DME-392499 Metabolism of proteins XP_046682182.1 Q9VJG5 R-DME-446203 Asparagine N-linked glycosylation XP_046682182.1 Q9VJG5 R-DME-5173105 O-linked glycosylation XP_046682182.1 Q9VJG5 R-DME-597592 Post-translational protein modification XP_046682182.1 Q9VJG5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682182.1 Q9VJG5 R-DME-8931838 DAG1 glycosylations XP_046682182.1 Q9VJG5 R-DME-948021 Transport to the Golgi and subsequent modification XP_046682182.1 Q9VJG5 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046682182.1 Q9VJG5 R-DME-975578 Reactions specific to the complex N-glycan synthesis pathway XP_046682182.1 Q9VJG5 R-DME-9939291 Matriglycan biosynthesis on DAG1 XP_046661304.1 Q9VJD1 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046661304.1 Q9VJD1 R-DME-392499 Metabolism of proteins XP_046661304.1 Q9VJD1 R-DME-597592 Post-translational protein modification XP_046661304.1 Q9VJD1 R-DME-8957275 Post-translational protein phosphorylation XP_046663985.1 P98149 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046663985.1 P98149 R-DME-1169091 Activation of NF-kappaB in B cells XP_046663985.1 P98149 R-DME-1280215 Cytokine Signaling in Immune system XP_046663985.1 P98149 R-DME-1280218 Adaptive Immune System XP_046663985.1 P98149 R-DME-1500931 Cell-Cell communication XP_046663985.1 P98149 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046663985.1 P98149 R-DME-162582 Signal Transduction XP_046663985.1 P98149 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046663985.1 P98149 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046663985.1 P98149 R-DME-166166 MyD88-independent TLR4 cascade XP_046663985.1 P98149 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046663985.1 P98149 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046663985.1 P98149 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046663985.1 P98149 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046663985.1 P98149 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046663985.1 P98149 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046663985.1 P98149 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046663985.1 P98149 R-DME-168249 Innate Immune System XP_046663985.1 P98149 R-DME-168256 Immune System XP_046663985.1 P98149 R-DME-168898 Toll-like Receptor Cascades XP_046663985.1 P98149 R-DME-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta XP_046663985.1 P98149 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046663985.1 P98149 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046663985.1 P98149 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046663985.1 P98149 R-DME-193639 p75NTR signals via NF-kB XP_046663985.1 P98149 R-DME-193704 p75 NTR receptor-mediated signalling XP_046663985.1 P98149 R-DME-202403 TCR signaling XP_046663985.1 P98149 R-DME-202424 Downstream TCR signaling XP_046663985.1 P98149 R-DME-209400 Transcriptional activtion by phosphorylated DL/DIF dimer XP_046663985.1 P98149 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046663985.1 P98149 R-DME-209449 Toll pathway XP_046663985.1 P98149 R-DME-209560 NF-kB is activated and signals survival XP_046663985.1 P98149 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046663985.1 P98149 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046663985.1 P98149 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046663985.1 P98149 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046663985.1 P98149 R-DME-2871837 FCERI mediated NF-kB activation XP_046663985.1 P98149 R-DME-2990846 SUMOylation XP_046663985.1 P98149 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046663985.1 P98149 R-DME-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production XP_046663985.1 P98149 R-DME-392499 Metabolism of proteins XP_046663985.1 P98149 R-DME-418990 Adherens junctions interactions XP_046663985.1 P98149 R-DME-421270 Cell-cell junction organization XP_046663985.1 P98149 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046663985.1 P98149 R-DME-446652 Interleukin-1 family signaling XP_046663985.1 P98149 R-DME-446728 Cell junction organization XP_046663985.1 P98149 R-DME-449147 Signaling by Interleukins XP_046663985.1 P98149 R-DME-4755510 SUMOylation of immune response proteins XP_046663985.1 P98149 R-DME-5252538 Drosophila signaling pathways XP_046663985.1 P98149 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046663985.1 P98149 R-DME-5621481 C-type lectin receptors (CLRs) XP_046663985.1 P98149 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046663985.1 P98149 R-DME-597592 Post-translational protein modification XP_046663985.1 P98149 R-DME-73887 Death Receptor Signaling XP_046663985.1 P98149 R-DME-8953897 Cellular responses to stimuli XP_046663985.1 P98149 R-DME-9020702 Interleukin-1 signaling XP_046663985.1 P98149 R-DME-933542 TRAF6 mediated NF-kB activation XP_046663985.1 P98149 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046663985.1 P98149 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046663985.1 P98149 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046663985.1 P98149 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046663985.1 P98149 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046663985.1 P98149 R-DME-9855142 Cellular responses to mechanical stimuli XP_046663985.1 P98149 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046663985.1 P98149 R-DME-9860931 Response of endothelial cells to shear stress XP_046663985.1 P98149 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046675347.1 Q8INY1 R-DME-392499 Metabolism of proteins XP_046675347.1 Q8INY1 R-DME-597592 Post-translational protein modification XP_046675347.1 Q8INY1 R-DME-8951664 Neddylation XP_046675754.1 Q9VJ33 R-DME-162582 Signal Transduction XP_046675754.1 Q9VJ33 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046675754.1 Q9VJ33 R-DME-199991 Membrane Trafficking XP_046675754.1 Q9VJ33 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046675754.1 Q9VJ33 R-DME-382551 Transport of small molecules XP_046675754.1 Q9VJ33 R-DME-392499 Metabolism of proteins XP_046675754.1 Q9VJ33 R-DME-5653656 Vesicle-mediated transport XP_046675754.1 Q9VJ33 R-DME-5688426 Deubiquitination XP_046675754.1 Q9VJ33 R-DME-5689603 UCH proteinases XP_046675754.1 Q9VJ33 R-DME-597592 Post-translational protein modification XP_046675754.1 Q9VJ33 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046675754.1 Q9VJ33 R-DME-8856828 Clathrin-mediated endocytosis XP_046675754.1 Q9VJ33 R-DME-8951664 Neddylation XP_046675754.1 Q9VJ33 R-DME-9006936 Signaling by TGFB family members XP_046675754.1 Q9VJ33 R-DME-917937 Iron uptake and transport XP_046660337.1 P16621 R-DME-112316 Neuronal System XP_046660337.1 P16621 R-DME-1266738 Developmental Biology XP_046660337.1 P16621 R-DME-162582 Signal Transduction XP_046660337.1 P16621 R-DME-168249 Innate Immune System XP_046660337.1 P16621 R-DME-168256 Immune System XP_046660337.1 P16621 R-DME-373755 Semaphorin interactions XP_046660337.1 P16621 R-DME-375165 NCAM signaling for neurite out-growth XP_046660337.1 P16621 R-DME-388844 Receptor-type tyrosine-protein phosphatases XP_046660337.1 P16621 R-DME-416700 Other semaphorin interactions XP_046660337.1 P16621 R-DME-422475 Axon guidance XP_046660337.1 P16621 R-DME-5673001 RAF/MAP kinase cascade XP_046660337.1 P16621 R-DME-5683057 MAPK family signaling cascades XP_046660337.1 P16621 R-DME-5684996 MAPK1/MAPK3 signaling XP_046660337.1 P16621 R-DME-6794362 Protein-protein interactions at synapses XP_046660337.1 P16621 R-DME-6798695 Neutrophil degranulation XP_046660337.1 P16621 R-DME-74752 Signaling by Insulin receptor XP_046660337.1 P16621 R-DME-77387 Insulin receptor recycling XP_046660337.1 P16621 R-DME-8849932 Synaptic adhesion-like molecules XP_046660337.1 P16621 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660337.1 P16621 R-DME-9675108 Nervous system development XP_046676081.1 P54631 R-DME-109582 Hemostasis XP_046676081.1 P54631 R-DME-114608 Platelet degranulation XP_046676081.1 P54631 R-DME-76002 Platelet activation, signaling and aggregation XP_046676081.1 P54631 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046680830.1 Q9VIU7 R-DME-162699 Synthesis of dolichyl-phosphate mannose XP_046680830.1 Q9VIU7 R-DME-163125 Post-translational modification: synthesis of GPI-anchored proteins XP_046680830.1 Q9VIU7 R-DME-392499 Metabolism of proteins XP_046680830.1 Q9VIU7 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046680830.1 Q9VIU7 R-DME-446203 Asparagine N-linked glycosylation XP_046680830.1 Q9VIU7 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046680830.1 Q9VIU7 R-DME-597592 Post-translational protein modification XP_046676547.1 P25722 R-DME-1430728 Metabolism XP_046676547.1 P25722 R-DME-1630316 Glycosaminoglycan metabolism XP_046676547.1 P25722 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046676547.1 P25722 R-DME-2022928 HS-GAG biosynthesis XP_046676547.1 P25722 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046667783.1 Q9VIQ8 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046667783.1 Q9VIQ8 R-DME-1430728 Metabolism XP_046667783.1 Q9VIQ8 R-DME-212436 Generic Transcription Pathway XP_046667783.1 Q9VIQ8 R-DME-2262752 Cellular responses to stress XP_046667783.1 Q9VIQ8 R-DME-3700989 Transcriptional Regulation by TP53 XP_046667783.1 Q9VIQ8 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046667783.1 Q9VIQ8 R-DME-611105 Respiratory electron transport XP_046667783.1 Q9VIQ8 R-DME-73857 RNA Polymerase II Transcription XP_046667783.1 Q9VIQ8 R-DME-74160 Gene expression (Transcription) XP_046667783.1 Q9VIQ8 R-DME-8953897 Cellular responses to stimuli XP_046667783.1 Q9VIQ8 R-DME-9707564 Cytoprotection by HMOX1 XP_046667783.1 Q9VIQ8 R-DME-9711123 Cellular response to chemical stress XP_046667783.1 Q9VIQ8 R-DME-9864848 Complex IV assembly XP_046679589.1 A0A0U1RVK6 R-DME-1430728 Metabolism XP_046679589.1 A0A0U1RVK6 R-DME-70263 Gluconeogenesis XP_046679589.1 A0A0U1RVK6 R-DME-70326 Glucose metabolism XP_046679589.1 A0A0U1RVK6 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046677005.1 A8DZ19 R-DME-1266738 Developmental Biology XP_046677005.1 A8DZ19 R-DME-1500931 Cell-Cell communication XP_046677005.1 A8DZ19 R-DME-162582 Signal Transduction XP_046677005.1 A8DZ19 R-DME-177929 Signaling by EGFR XP_046677005.1 A8DZ19 R-DME-182971 EGFR downregulation XP_046677005.1 A8DZ19 R-DME-193648 NRAGE signals death through JNK XP_046677005.1 A8DZ19 R-DME-193704 p75 NTR receptor-mediated signalling XP_046677005.1 A8DZ19 R-DME-194315 Signaling by Rho GTPases XP_046677005.1 A8DZ19 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046677005.1 A8DZ19 R-DME-2682334 EPH-Ephrin signaling XP_046677005.1 A8DZ19 R-DME-372790 Signaling by GPCR XP_046677005.1 A8DZ19 R-DME-388396 GPCR downstream signalling XP_046677005.1 A8DZ19 R-DME-3928664 Ephrin signaling XP_046677005.1 A8DZ19 R-DME-397795 G-protein beta:gamma signalling XP_046677005.1 A8DZ19 R-DME-416482 G alpha (12/13) signalling events XP_046677005.1 A8DZ19 R-DME-422475 Axon guidance XP_046677005.1 A8DZ19 R-DME-446353 Cell-extracellular matrix interactions XP_046677005.1 A8DZ19 R-DME-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components XP_046677005.1 A8DZ19 R-DME-446728 Cell junction organization XP_046677005.1 A8DZ19 R-DME-73887 Death Receptor Signaling XP_046677005.1 A8DZ19 R-DME-8964616 G beta:gamma signalling through CDC42 XP_046677005.1 A8DZ19 R-DME-8980692 RHOA GTPase cycle XP_046677005.1 A8DZ19 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046677005.1 A8DZ19 R-DME-9012999 RHO GTPase cycle XP_046677005.1 A8DZ19 R-DME-9013148 CDC42 GTPase cycle XP_046677005.1 A8DZ19 R-DME-9013149 RAC1 GTPase cycle XP_046677005.1 A8DZ19 R-DME-9013406 RHOQ GTPase cycle XP_046677005.1 A8DZ19 R-DME-9013420 RHOU GTPase cycle XP_046677005.1 A8DZ19 R-DME-9013424 RHOV GTPase cycle XP_046677005.1 A8DZ19 R-DME-9675108 Nervous system development XP_046677005.1 A8DZ19 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046662753.1 Q9VIE8 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046662753.1 Q9VIE8 R-DME-1430728 Metabolism XP_046662753.1 Q9VIE8 R-DME-392499 Metabolism of proteins XP_046662753.1 Q9VIE8 R-DME-71403 Citric acid cycle (TCA cycle) XP_046662753.1 Q9VIE8 R-DME-9837999 Mitochondrial protein degradation XP_046662753.1 Q9VIE8 R-DME-9854311 Maturation of TCA enzymes and regulation of TCA cycle XP_046672222.1 Q9VIE7 R-DME-1430728 Metabolism XP_046672222.1 Q9VIE7 R-DME-15869 Metabolism of nucleotides XP_046672222.1 Q9VIE7 R-DME-73817 Purine ribonucleoside monophosphate biosynthesis XP_046672222.1 Q9VIE7 R-DME-8956320 Nucleotide biosynthesis XP_046672222.1 Q9VIE7 R-DME-9748784 Drug ADME XP_046672222.1 Q9VIE7 R-DME-9748787 Azathioprine ADME XP_046670866.1 Q9VIF3 R-DME-1430728 Metabolism XP_046670866.1 Q9VIF3 R-DME-196854 Metabolism of vitamins and cofactors XP_046670866.1 Q9VIF3 R-DME-2142789 Ubiquinol biosynthesis XP_046670866.1 Q9VIF3 R-DME-8978934 Metabolism of cofactors XP_046667458.1 M9ND00 R-DME-1266738 Developmental Biology XP_046667458.1 M9ND00 R-DME-162582 Signal Transduction XP_046667458.1 M9ND00 R-DME-193648 NRAGE signals death through JNK XP_046667458.1 M9ND00 R-DME-193704 p75 NTR receptor-mediated signalling XP_046667458.1 M9ND00 R-DME-194315 Signaling by Rho GTPases XP_046667458.1 M9ND00 R-DME-199991 Membrane Trafficking XP_046667458.1 M9ND00 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046667458.1 M9ND00 R-DME-2682334 EPH-Ephrin signaling XP_046667458.1 M9ND00 R-DME-372790 Signaling by GPCR XP_046667458.1 M9ND00 R-DME-388396 GPCR downstream signalling XP_046667458.1 M9ND00 R-DME-3928662 EPHB-mediated forward signaling XP_046667458.1 M9ND00 R-DME-416482 G alpha (12/13) signalling events XP_046667458.1 M9ND00 R-DME-422475 Axon guidance XP_046667458.1 M9ND00 R-DME-5653656 Vesicle-mediated transport XP_046667458.1 M9ND00 R-DME-73887 Death Receptor Signaling XP_046667458.1 M9ND00 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046667458.1 M9ND00 R-DME-8856828 Clathrin-mediated endocytosis XP_046667458.1 M9ND00 R-DME-9012999 RHO GTPase cycle XP_046667458.1 M9ND00 R-DME-9013148 CDC42 GTPase cycle XP_046667458.1 M9ND00 R-DME-9013406 RHOQ GTPase cycle XP_046667458.1 M9ND00 R-DME-9013420 RHOU GTPase cycle XP_046667458.1 M9ND00 R-DME-9675108 Nervous system development XP_046667458.1 M9ND00 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046688782.1 Q9VHS2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046688782.1 Q9VHS2 R-DME-1430728 Metabolism XP_046688782.1 Q9VHS2 R-DME-212436 Generic Transcription Pathway XP_046688782.1 Q9VHS2 R-DME-2262752 Cellular responses to stress XP_046688782.1 Q9VHS2 R-DME-3700989 Transcriptional Regulation by TP53 XP_046688782.1 Q9VHS2 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046688782.1 Q9VHS2 R-DME-611105 Respiratory electron transport XP_046688782.1 Q9VHS2 R-DME-73857 RNA Polymerase II Transcription XP_046688782.1 Q9VHS2 R-DME-74160 Gene expression (Transcription) XP_046688782.1 Q9VHS2 R-DME-8953897 Cellular responses to stimuli XP_046688782.1 Q9VHS2 R-DME-9707564 Cytoprotection by HMOX1 XP_046688782.1 Q9VHS2 R-DME-9711123 Cellular response to chemical stress XP_046688782.1 Q9VHS2 R-DME-9864848 Complex IV assembly XP_046666054.1 Q9VHS7 R-DME-1268020 Mitochondrial protein import XP_046666054.1 Q9VHS7 R-DME-1430728 Metabolism XP_046666054.1 Q9VHS7 R-DME-196854 Metabolism of vitamins and cofactors XP_046666054.1 Q9VHS7 R-DME-2142789 Ubiquinol biosynthesis XP_046666054.1 Q9VHS7 R-DME-8978934 Metabolism of cofactors XP_046666054.1 Q9VHS7 R-DME-9609507 Protein localization XP_046684204.1 Q9VHN7 R-DME-1430728 Metabolism XP_046684204.1 Q9VHN7 R-DME-163685 Integration of energy metabolism XP_046684204.1 Q9VHN7 R-DME-163754 Insulin effects increased synthesis of Xylulose-5-Phosphate XP_046684204.1 Q9VHN7 R-DME-71336 Pentose phosphate pathway XP_046684204.1 Q9VHN7 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046660035.1 O61444 R-DME-1280215 Cytokine Signaling in Immune system XP_046660035.1 O61444 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046660035.1 O61444 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046660035.1 O61444 R-DME-166166 MyD88-independent TLR4 cascade XP_046660035.1 O61444 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046660035.1 O61444 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046660035.1 O61444 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046660035.1 O61444 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046660035.1 O61444 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046660035.1 O61444 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046660035.1 O61444 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046660035.1 O61444 R-DME-168249 Innate Immune System XP_046660035.1 O61444 R-DME-168256 Immune System XP_046660035.1 O61444 R-DME-168898 Toll-like Receptor Cascades XP_046660035.1 O61444 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046660035.1 O61444 R-DME-2262752 Cellular responses to stress XP_046660035.1 O61444 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046660035.1 O61444 R-DME-2559580 Oxidative Stress Induced Senescence XP_046660035.1 O61444 R-DME-2559583 Cellular Senescence XP_046660035.1 O61444 R-DME-2871796 FCERI mediated MAPK activation XP_046660035.1 O61444 R-DME-448424 Interleukin-17 signaling XP_046660035.1 O61444 R-DME-449147 Signaling by Interleukins XP_046660035.1 O61444 R-DME-450294 MAP kinase activation XP_046660035.1 O61444 R-DME-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 XP_046660035.1 O61444 R-DME-8953897 Cellular responses to stimuli XP_046660035.1 O61444 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046660035.1 O61444 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046660035.1 O61444 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046660035.1 O61444 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046669435.1 Q9VHK6 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046669435.1 Q9VHK6 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046669435.1 Q9VHK6 R-DME-1430728 Metabolism XP_046669435.1 Q9VHK6 R-DME-611105 Respiratory electron transport XP_046669435.1 Q9VHK6 R-DME-9865881 Complex III assembly XP_046668454.1 Q95U38 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046668454.1 Q95U38 R-DME-1430728 Metabolism XP_046668454.1 Q95U38 R-DME-71403 Citric acid cycle (TCA cycle) XP_046670377.1 Q9VHI1 R-DME-112382 Formation of RNA Pol II elongation complex XP_046670377.1 Q9VHI1 R-DME-162582 Signal Transduction XP_046670377.1 Q9VHI1 R-DME-195721 Signaling by WNT XP_046670377.1 Q9VHI1 R-DME-201681 TCF dependent signaling in response to WNT XP_046670377.1 Q9VHI1 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046670377.1 Q9VHI1 R-DME-392499 Metabolism of proteins XP_046670377.1 Q9VHI1 R-DME-4839726 Chromatin organization XP_046670377.1 Q9VHI1 R-DME-5358351 Signaling by Hedgehog XP_046670377.1 Q9VHI1 R-DME-5632684 Hedgehog 'on' state XP_046670377.1 Q9VHI1 R-DME-597592 Post-translational protein modification XP_046670377.1 Q9VHI1 R-DME-674695 RNA Polymerase II Pre-transcription Events XP_046670377.1 Q9VHI1 R-DME-73857 RNA Polymerase II Transcription XP_046670377.1 Q9VHI1 R-DME-74160 Gene expression (Transcription) XP_046670377.1 Q9VHI1 R-DME-75955 RNA Polymerase II Transcription Elongation XP_046670377.1 Q9VHI1 R-DME-8852135 Protein ubiquitination XP_046670377.1 Q9VHI1 R-DME-8866654 E3 ubiquitin ligases ubiquitinate target proteins XP_046670377.1 Q9VHI1 R-DME-9932444 ATP-dependent chromatin remodelers XP_046670377.1 Q9VHI1 R-DME-9937848 CHD chromatin remodelers XP_046670377.1 Q9VHI1 R-DME-9943411 CHD1 and CHD2 subfamily XP_046669069.1 P25822 R-DME-199991 Membrane Trafficking XP_046669069.1 P25822 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046669069.1 P25822 R-DME-432722 Golgi Associated Vesicle Biogenesis XP_046669069.1 P25822 R-DME-5653656 Vesicle-mediated transport XP_046658799.1 Q24451 R-DME-392499 Metabolism of proteins XP_046658799.1 Q24451 R-DME-446203 Asparagine N-linked glycosylation XP_046658799.1 Q24451 R-DME-597592 Post-translational protein modification XP_046658799.1 Q24451 R-DME-948021 Transport to the Golgi and subsequent modification XP_046658799.1 Q24451 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046658799.1 Q24451 R-DME-975578 Reactions specific to the complex N-glycan synthesis pathway XP_046668728.1 Q9VH90 R-DME-162582 Signal Transduction XP_046668728.1 Q9VH90 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046668728.1 Q9VH90 R-DME-195721 Signaling by WNT XP_046668728.1 Q9VH90 R-DME-392499 Metabolism of proteins XP_046668728.1 Q9VH90 R-DME-5688426 Deubiquitination XP_046668728.1 Q9VH90 R-DME-5689896 Ovarian tumor domain proteases XP_046668728.1 Q9VH90 R-DME-597592 Post-translational protein modification XP_046679614.1 P08646 R-DME-109582 Hemostasis XP_046679614.1 P08646 R-DME-1227986 Signaling by ERBB2 XP_046679614.1 P08646 R-DME-1236394 Signaling by ERBB4 XP_046679614.1 P08646 R-DME-1250347 SHC1 events in ERBB4 signaling XP_046679614.1 P08646 R-DME-1266738 Developmental Biology XP_046679614.1 P08646 R-DME-1280215 Cytokine Signaling in Immune system XP_046679614.1 P08646 R-DME-1433557 Signaling by SCF-KIT XP_046679614.1 P08646 R-DME-162582 Signal Transduction XP_046679614.1 P08646 R-DME-166520 Signaling by NTRKs XP_046679614.1 P08646 R-DME-167044 Signalling to RAS XP_046679614.1 P08646 R-DME-168249 Innate Immune System XP_046679614.1 P08646 R-DME-168256 Immune System XP_046679614.1 P08646 R-DME-171007 p38MAPK events XP_046679614.1 P08646 R-DME-177929 Signaling by EGFR XP_046679614.1 P08646 R-DME-179812 GRB2 events in EGFR signaling XP_046679614.1 P08646 R-DME-180336 SHC1 events in EGFR signaling XP_046679614.1 P08646 R-DME-186763 Downstream signal transduction XP_046679614.1 P08646 R-DME-186797 Signaling by PDGF XP_046679614.1 P08646 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046679614.1 P08646 R-DME-187687 Signalling to ERKs XP_046679614.1 P08646 R-DME-190236 Signaling by FGFR XP_046679614.1 P08646 R-DME-194138 Signaling by VEGF XP_046679614.1 P08646 R-DME-195721 Signaling by WNT XP_046679614.1 P08646 R-DME-1963640 GRB2 events in ERBB2 signaling XP_046679614.1 P08646 R-DME-202733 Cell surface interactions at the vascular wall XP_046679614.1 P08646 R-DME-210993 Tie2 Signaling XP_046679614.1 P08646 R-DME-212436 Generic Transcription Pathway XP_046679614.1 P08646 R-DME-2172127 DAP12 interactions XP_046679614.1 P08646 R-DME-2179392 EGFR Transactivation by Gastrin XP_046679614.1 P08646 R-DME-2424491 DAP12 signaling XP_046679614.1 P08646 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046679614.1 P08646 R-DME-2682334 EPH-Ephrin signaling XP_046679614.1 P08646 R-DME-2871796 FCERI mediated MAPK activation XP_046679614.1 P08646 R-DME-372790 Signaling by GPCR XP_046679614.1 P08646 R-DME-375165 NCAM signaling for neurite out-growth XP_046679614.1 P08646 R-DME-3858494 Beta-catenin independent WNT signaling XP_046679614.1 P08646 R-DME-388396 GPCR downstream signalling XP_046679614.1 P08646 R-DME-3928662 EPHB-mediated forward signaling XP_046679614.1 P08646 R-DME-4086398 Ca2+ pathway XP_046679614.1 P08646 R-DME-416476 G alpha (q) signalling events XP_046679614.1 P08646 R-DME-422475 Axon guidance XP_046679614.1 P08646 R-DME-432553 Phosphorylation of PER and TIM XP_046679614.1 P08646 R-DME-432626 Circadian Clock pathway XP_046679614.1 P08646 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046679614.1 P08646 R-DME-5218921 VEGFR2 mediated cell proliferation XP_046679614.1 P08646 R-DME-5252538 Drosophila signaling pathways XP_046679614.1 P08646 R-DME-5621481 C-type lectin receptors (CLRs) XP_046679614.1 P08646 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046679614.1 P08646 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046679614.1 P08646 R-DME-5654688 SHC-mediated cascade:FGFR1 XP_046679614.1 P08646 R-DME-5654693 FRS-mediated FGFR1 signaling XP_046679614.1 P08646 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046679614.1 P08646 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046679614.1 P08646 R-DME-5654700 FRS-mediated FGFR2 signaling XP_046679614.1 P08646 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046679614.1 P08646 R-DME-5654706 FRS-mediated FGFR3 signaling XP_046679614.1 P08646 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046679614.1 P08646 R-DME-5654712 FRS-mediated FGFR4 signaling XP_046679614.1 P08646 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046679614.1 P08646 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046679614.1 P08646 R-DME-5654736 Signaling by FGFR1 XP_046679614.1 P08646 R-DME-5654738 Signaling by FGFR2 XP_046679614.1 P08646 R-DME-5654741 Signaling by FGFR3 XP_046679614.1 P08646 R-DME-5654743 Signaling by FGFR4 XP_046679614.1 P08646 R-DME-5658442 Regulation of RAS by GAPs XP_046679614.1 P08646 R-DME-5673000 RAF activation XP_046679614.1 P08646 R-DME-5673001 RAF/MAP kinase cascade XP_046679614.1 P08646 R-DME-5674135 MAP2K and MAPK activation XP_046679614.1 P08646 R-DME-5675221 Negative regulation of MAPK pathway XP_046679614.1 P08646 R-DME-5683057 MAPK family signaling cascades XP_046679614.1 P08646 R-DME-5684996 MAPK1/MAPK3 signaling XP_046679614.1 P08646 R-DME-6798695 Neutrophil degranulation XP_046679614.1 P08646 R-DME-73857 RNA Polymerase II Transcription XP_046679614.1 P08646 R-DME-74160 Gene expression (Transcription) XP_046679614.1 P08646 R-DME-881907 Gastrin-CREB signalling pathway via PKC and MAPK XP_046679614.1 P08646 R-DME-8848021 Signaling by PTK6 XP_046679614.1 P08646 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046679614.1 P08646 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046679614.1 P08646 R-DME-8939211 ESR-mediated signaling XP_046679614.1 P08646 R-DME-8951936 RUNX3 regulates p14-ARF XP_046679614.1 P08646 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046679614.1 P08646 R-DME-9006931 Signaling by Nuclear Receptors XP_046679614.1 P08646 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046679614.1 P08646 R-DME-9009391 Extra-nuclear estrogen signaling XP_046679614.1 P08646 R-DME-9607240 FLT3 Signaling XP_046679614.1 P08646 R-DME-9634635 Estrogen-stimulated signaling through PRKCZ XP_046679614.1 P08646 R-DME-9648002 RAS processing XP_046679614.1 P08646 R-DME-9675108 Nervous system development XP_046688775.1 Q9VH78 R-DME-392499 Metabolism of proteins XP_046688775.1 Q9VH78 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046688775.1 Q9VH78 R-DME-446203 Asparagine N-linked glycosylation XP_046688775.1 Q9VH78 R-DME-597592 Post-translational protein modification XP_046668624.1 P36872 R-DME-1640170 Cell Cycle XP_046668624.1 P36872 R-DME-209155 Phosphorylation of AXN and APC XP_046668624.1 P36872 R-DME-209159 Assembly of the CI containing complexes XP_046668624.1 P36872 R-DME-209190 Phosphorylation of CI XP_046668624.1 P36872 R-DME-209214 Phosphorylation of SMO XP_046668624.1 P36872 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046668624.1 P36872 R-DME-209392 Hedgehog pathway XP_046668624.1 P36872 R-DME-209396 Phosphorylation of ARM XP_046668624.1 P36872 R-DME-209412 Wingless pathway XP_046668624.1 P36872 R-DME-209413 Assembly of the 'destruction complex' XP_046668624.1 P36872 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046668624.1 P36872 R-DME-209441 WG ligand not bound to FZ receptors XP_046668624.1 P36872 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046668624.1 P36872 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046668624.1 P36872 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046668624.1 P36872 R-DME-209469 WG ligand bound to FZ receptors XP_046668624.1 P36872 R-DME-216217 Activation of SMO XP_046668624.1 P36872 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046668624.1 P36872 R-DME-2995383 Initiation of Nuclear Envelope (NE) Reformation XP_046668624.1 P36872 R-DME-2995410 Nuclear Envelope (NE) Reassembly XP_046668624.1 P36872 R-DME-432553 Phosphorylation of PER and TIM XP_046668624.1 P36872 R-DME-432620 Dephosphorylation of PER XP_046668624.1 P36872 R-DME-432626 Circadian Clock pathway XP_046668624.1 P36872 R-DME-453274 Mitotic G2-G2/M phases XP_046668624.1 P36872 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046668624.1 P36872 R-DME-5252538 Drosophila signaling pathways XP_046668624.1 P36872 R-DME-68882 Mitotic Anaphase XP_046668624.1 P36872 R-DME-68886 M Phase XP_046668624.1 P36872 R-DME-69231 Cyclin D associated events in G1 XP_046668624.1 P36872 R-DME-69236 G1 Phase XP_046668624.1 P36872 R-DME-69273 Cyclin A/B1/B2 associated events during G2/M transition XP_046668624.1 P36872 R-DME-69275 G2/M Transition XP_046668624.1 P36872 R-DME-69278 Cell Cycle, Mitotic XP_046668624.1 P36872 R-DME-8953854 Metabolism of RNA XP_046668624.1 P36872 R-DME-8953897 Cellular responses to stimuli XP_046668624.1 P36872 R-DME-927802 Nonsense-Mediated Decay (NMD) XP_046668624.1 P36872 R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) XP_046668624.1 P36872 R-DME-9855142 Cellular responses to mechanical stimuli XP_046668624.1 P36872 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046668624.1 P36872 R-DME-9860931 Response of endothelial cells to shear stress XP_046668169.1 Q9VH07 R-DME-162582 Signal Transduction XP_046668169.1 Q9VH07 R-DME-195721 Signaling by WNT XP_046668169.1 Q9VH07 R-DME-201681 TCF dependent signaling in response to WNT XP_046668169.1 Q9VH07 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046668169.1 Q9VH07 R-DME-392499 Metabolism of proteins XP_046668169.1 Q9VH07 R-DME-5688426 Deubiquitination XP_046668169.1 Q9VH07 R-DME-5689603 UCH proteinases XP_046668169.1 Q9VH07 R-DME-5689880 Ub-specific processing proteases XP_046668169.1 Q9VH07 R-DME-5696394 DNA Damage Recognition in GG-NER XP_046668169.1 Q9VH07 R-DME-5696398 Nucleotide Excision Repair XP_046668169.1 Q9VH07 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046668169.1 Q9VH07 R-DME-597592 Post-translational protein modification XP_046668169.1 Q9VH07 R-DME-73894 DNA Repair XP_046687896.1 A0A0B4KFQ5 R-DME-168249 Innate Immune System XP_046687896.1 A0A0B4KFQ5 R-DME-168256 Immune System XP_046687896.1 A0A0B4KFQ5 R-DME-6798695 Neutrophil degranulation XP_046686957.1 Q9VGQ1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046686957.1 Q9VGQ1 R-DME-1430728 Metabolism XP_046686957.1 Q9VGQ1 R-DME-389661 Glyoxylate metabolism and glycine degradation XP_046686957.1 Q9VGQ1 R-DME-392499 Metabolism of proteins XP_046686957.1 Q9VGQ1 R-DME-597592 Post-translational protein modification XP_046686957.1 Q9VGQ1 R-DME-6783984 Glycine degradation XP_046686957.1 Q9VGQ1 R-DME-71064 Lysine catabolism XP_046686957.1 Q9VGQ1 R-DME-71291 Metabolism of amino acids and derivatives XP_046686957.1 Q9VGQ1 R-DME-71403 Citric acid cycle (TCA cycle) XP_046686957.1 Q9VGQ1 R-DME-9853506 OGDH complex synthesizes succinyl-CoA from 2-OG XP_046686957.1 Q9VGQ1 R-DME-9857492 Protein lipoylation XP_046686957.1 Q9VGQ1 R-DME-9858328 OADH complex synthesizes glutaryl-CoA from 2-OA XP_046669628.1 Q9VGS3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046669628.1 Q9VGS3 R-DME-1430728 Metabolism XP_046669628.1 Q9VGS3 R-DME-71403 Citric acid cycle (TCA cycle) XP_046682560.1 Q8INK6 R-DME-168249 Innate Immune System XP_046682560.1 Q8INK6 R-DME-168256 Immune System XP_046682560.1 Q8INK6 R-DME-6798695 Neutrophil degranulation XP_046682560.1 Q8INK6 R-DME-6803157 Antimicrobial peptides XP_046661067.1 Q94514 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046661067.1 Q94514 R-DME-1430728 Metabolism XP_046661067.1 Q94514 R-DME-212436 Generic Transcription Pathway XP_046661067.1 Q94514 R-DME-2262752 Cellular responses to stress XP_046661067.1 Q94514 R-DME-3700989 Transcriptional Regulation by TP53 XP_046661067.1 Q94514 R-DME-392499 Metabolism of proteins XP_046661067.1 Q94514 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046661067.1 Q94514 R-DME-611105 Respiratory electron transport XP_046661067.1 Q94514 R-DME-73857 RNA Polymerase II Transcription XP_046661067.1 Q94514 R-DME-74160 Gene expression (Transcription) XP_046661067.1 Q94514 R-DME-8953897 Cellular responses to stimuli XP_046661067.1 Q94514 R-DME-9707564 Cytoprotection by HMOX1 XP_046661067.1 Q94514 R-DME-9711123 Cellular response to chemical stress XP_046661067.1 Q94514 R-DME-9837999 Mitochondrial protein degradation XP_046661067.1 Q94514 R-DME-9864848 Complex IV assembly XP_046658213.1 Q9VG74 R-DME-392499 Metabolism of proteins XP_046658213.1 Q9VG74 R-DME-4085001 Sialic acid metabolism XP_046658213.1 Q9VG74 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046658213.1 Q9VG74 R-DME-446203 Asparagine N-linked glycosylation XP_046658213.1 Q9VG74 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046658213.1 Q9VG74 R-DME-597592 Post-translational protein modification XP_046682828.1 P12982 R-DME-350416 Regulation of non-muscle Myosin II XP_046682828.1 P12982 R-DME-350431 Planar Cell Polarity pathway XP_046682828.1 P12982 R-DME-350480 Activation of non-muscle Myosin II XP_046682828.1 P12982 R-DME-432626 Circadian Clock pathway XP_046682828.1 P12982 R-DME-450736 Activation of Downstream Effectors XP_046682828.1 P12982 R-DME-450799 RHO1 signalling XP_046682828.1 P12982 R-DME-5252538 Drosophila signaling pathways XP_046682828.1 P12982 R-DME-538898 Dephosphorylation of TIM XP_046682828.1 P12982 R-DME-72187 mRNA 3'-end processing XP_046682828.1 P12982 R-DME-72203 Processing of Capped Intron-Containing Pre-mRNA XP_046682828.1 P12982 R-DME-8953854 Metabolism of RNA XP_046682828.1 P12982 R-DME-9770562 mRNA Polyadenylation XP_046659157.1 Q27279 R-DME-209159 Assembly of the CI containing complexes XP_046659157.1 Q27279 R-DME-209392 Hedgehog pathway XP_046659157.1 Q27279 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046659157.1 Q27279 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046659157.1 Q27279 R-DME-216119 Activation of CI XP_046659157.1 Q27279 R-DME-5252538 Drosophila signaling pathways XP_046659157.1 Q9VG38 R-DME-162582 Signal Transduction XP_046659157.1 Q9VG38 R-DME-5358351 Signaling by Hedgehog XP_046659157.1 Q9VG38 R-DME-5610780 Degradation of GLI1 by the proteasome XP_046659157.1 Q9VG38 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046659157.1 Q9VG38 R-DME-5610787 Hedgehog 'off' state XP_046659157.1 Q9VG38 R-DME-5632684 Hedgehog 'on' state XP_046660713.1 P05049 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046660713.1 P05049 R-DME-209449 Toll pathway XP_046660713.1 P05049 R-DME-5252538 Drosophila signaling pathways XP_046660060.1 Q9Y166 R-DME-1430728 Metabolism XP_046660060.1 Q9Y166 R-DME-1614517 Sulfide oxidation to sulfate XP_046660060.1 Q9Y166 R-DME-1614558 Degradation of cysteine and homocysteine XP_046660060.1 Q9Y166 R-DME-1614635 Sulfur amino acid metabolism XP_046660060.1 Q9Y166 R-DME-382551 Transport of small molecules XP_046660060.1 Q9Y166 R-DME-425407 SLC-mediated transmembrane transport XP_046660060.1 Q9Y166 R-DME-428643 Organic anion transport by SLC5/17/25 transporters XP_046660060.1 Q9Y166 R-DME-71291 Metabolism of amino acids and derivatives XP_046660060.1 Q9Y166 R-DME-9955298 SLC-mediated transport of organic anions XP_046666318.1 Q9VFR3 R-DME-168249 Innate Immune System XP_046666318.1 Q9VFR3 R-DME-168256 Immune System XP_046666318.1 Q9VFR3 R-DME-189085 Digestion of dietary carbohydrate XP_046666318.1 Q9VFR3 R-DME-6798695 Neutrophil degranulation XP_046666318.1 Q9VFR3 R-DME-8935690 Digestion XP_046666318.1 Q9VFR3 R-DME-8963743 Digestion and absorption XP_046675731.1 Q9VFS6 R-DME-6807505 RNA polymerase II transcribes snRNA genes XP_046675731.1 Q9VFS6 R-DME-73857 RNA Polymerase II Transcription XP_046675731.1 Q9VFS6 R-DME-74160 Gene expression (Transcription) XP_046667966.1 Q95V55 R-DME-110478 Insulin signaling pathway XP_046667966.1 Q95V55 R-DME-110526 Insulin receptor mediated signaling XP_046667966.1 Q95V55 R-DME-1181150 Signaling by NODAL XP_046667966.1 Q95V55 R-DME-1257604 PIP3 activates AKT signaling XP_046667966.1 Q95V55 R-DME-1266738 Developmental Biology XP_046667966.1 Q95V55 R-DME-1280215 Cytokine Signaling in Immune system XP_046667966.1 Q95V55 R-DME-162582 Signal Transduction XP_046667966.1 Q95V55 R-DME-168256 Immune System XP_046667966.1 Q95V55 R-DME-186712 Regulation of beta-cell development XP_046667966.1 Q95V55 R-DME-198693 AKT phosphorylates targets in the nucleus XP_046667966.1 Q95V55 R-DME-210745 Regulation of gene expression in beta cells XP_046667966.1 Q95V55 R-DME-211163 AKT-mediated inactivation of FOXO1A XP_046667966.1 Q95V55 R-DME-212436 Generic Transcription Pathway XP_046667966.1 Q95V55 R-DME-2262752 Cellular responses to stress XP_046667966.1 Q95V55 R-DME-392499 Metabolism of proteins XP_046667966.1 Q95V55 R-DME-5252538 Drosophila signaling pathways XP_046667966.1 Q95V55 R-DME-5683057 MAPK family signaling cascades XP_046667966.1 Q95V55 R-DME-5687128 MAPK6/MAPK4 signaling XP_046667966.1 Q95V55 R-DME-5688426 Deubiquitination XP_046667966.1 Q95V55 R-DME-5689880 Ub-specific processing proteases XP_046667966.1 Q95V55 R-DME-597592 Post-translational protein modification XP_046667966.1 Q95V55 R-DME-73857 RNA Polymerase II Transcription XP_046667966.1 Q95V55 R-DME-74160 Gene expression (Transcription) XP_046667966.1 Q95V55 R-DME-8939211 ESR-mediated signaling XP_046667966.1 Q95V55 R-DME-8953897 Cellular responses to stimuli XP_046667966.1 Q95V55 R-DME-9006925 Intracellular signaling by second messengers XP_046667966.1 Q95V55 R-DME-9006931 Signaling by Nuclear Receptors XP_046667966.1 Q95V55 R-DME-9009391 Extra-nuclear estrogen signaling XP_046667966.1 Q95V55 R-DME-9607240 FLT3 Signaling XP_046667966.1 Q95V55 R-DME-9614085 FOXO-mediated transcription XP_046667966.1 Q95V55 R-DME-9614399 Regulation of localization of FOXO transcription factors XP_046667966.1 Q95V55 R-DME-9617629 Regulation of FOXO transcriptional activity by acetylation XP_046667966.1 Q95V55 R-DME-9617828 FOXO-mediated transcription of cell cycle genes XP_046667966.1 Q95V55 R-DME-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling XP_046667966.1 Q95V55 R-DME-9841251 Mitochondrial unfolded protein response (UPRmt) XP_046674936.1 Q9VFI0 R-DME-1257604 PIP3 activates AKT signaling XP_046674936.1 Q9VFI0 R-DME-1280218 Adaptive Immune System XP_046674936.1 Q9VFI0 R-DME-162582 Signal Transduction XP_046674936.1 Q9VFI0 R-DME-168256 Immune System XP_046674936.1 Q9VFI0 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046674936.1 Q9VFI0 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046674936.1 Q9VFI0 R-DME-9006925 Intracellular signaling by second messengers XP_046674936.1 Q9VFI0 R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers XP_046674936.1 Q9VFI0 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046668646.1 P25867 R-DME-1234174 Cellular response to hypoxia XP_046668646.1 P25867 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046668646.1 P25867 R-DME-1280218 Adaptive Immune System XP_046668646.1 P25867 R-DME-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components XP_046668646.1 P25867 R-DME-141430 Inactivation of APC/C via direct inhibition of the APC/C complex XP_046668646.1 P25867 R-DME-162582 Signal Transduction XP_046668646.1 P25867 R-DME-1640170 Cell Cycle XP_046668646.1 P25867 R-DME-168249 Innate Immune System XP_046668646.1 P25867 R-DME-168256 Immune System XP_046668646.1 P25867 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046668646.1 P25867 R-DME-174048 APC/C:Cdc20 mediated degradation of Cyclin B XP_046668646.1 P25867 R-DME-174084 Autodegradation of Cdh1 by Cdh1:APC/C XP_046668646.1 P25867 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046668646.1 P25867 R-DME-174154 APC/C:Cdc20 mediated degradation of Securin XP_046668646.1 P25867 R-DME-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 XP_046668646.1 P25867 R-DME-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A XP_046668646.1 P25867 R-DME-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase XP_046668646.1 P25867 R-DME-176408 Regulation of APC/C activators between G1/S and early anaphase XP_046668646.1 P25867 R-DME-176409 APC/C:Cdc20 mediated degradation of mitotic proteins XP_046668646.1 P25867 R-DME-176412 Phosphorylation of the APC/C XP_046668646.1 P25867 R-DME-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins XP_046668646.1 P25867 R-DME-179409 APC-Cdc20 mediated degradation of Nek2A XP_046668646.1 P25867 R-DME-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint XP_046668646.1 P25867 R-DME-201451 Signaling by BMP XP_046668646.1 P25867 R-DME-202403 TCR signaling XP_046668646.1 P25867 R-DME-202424 Downstream TCR signaling XP_046668646.1 P25867 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046668646.1 P25867 R-DME-209392 Hedgehog pathway XP_046668646.1 P25867 R-DME-209412 Wingless pathway XP_046668646.1 P25867 R-DME-209441 WG ligand not bound to FZ receptors XP_046668646.1 P25867 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046668646.1 P25867 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046668646.1 P25867 R-DME-212436 Generic Transcription Pathway XP_046668646.1 P25867 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046668646.1 P25867 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046668646.1 P25867 R-DME-2262752 Cellular responses to stress XP_046668646.1 P25867 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046668646.1 P25867 R-DME-2467813 Separation of Sister Chromatids XP_046668646.1 P25867 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046668646.1 P25867 R-DME-2559582 Senescence-Associated Secretory Phenotype (SASP) XP_046668646.1 P25867 R-DME-2559583 Cellular Senescence XP_046668646.1 P25867 R-DME-2871837 FCERI mediated NF-kB activation XP_046668646.1 P25867 R-DME-392499 Metabolism of proteins XP_046668646.1 P25867 R-DME-453276 Regulation of mitotic cell cycle XP_046668646.1 P25867 R-DME-5252538 Drosophila signaling pathways XP_046668646.1 P25867 R-DME-5357905 Regulation of TNFR1 signaling XP_046668646.1 P25867 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046668646.1 P25867 R-DME-5621481 C-type lectin receptors (CLRs) XP_046668646.1 P25867 R-DME-5688426 Deubiquitination XP_046668646.1 P25867 R-DME-5689896 Ovarian tumor domain proteases XP_046668646.1 P25867 R-DME-597592 Post-translational protein modification XP_046668646.1 P25867 R-DME-68867 Assembly of the pre-replicative complex XP_046668646.1 P25867 R-DME-68882 Mitotic Anaphase XP_046668646.1 P25867 R-DME-68886 M Phase XP_046668646.1 P25867 R-DME-69002 DNA Replication Pre-Initiation XP_046668646.1 P25867 R-DME-69017 CDK-mediated phosphorylation and removal of Cdc6 XP_046668646.1 P25867 R-DME-69052 Switching of origins to a post-replicative state XP_046668646.1 P25867 R-DME-69239 Synthesis of DNA XP_046668646.1 P25867 R-DME-69242 S Phase XP_046668646.1 P25867 R-DME-69278 Cell Cycle, Mitotic XP_046668646.1 P25867 R-DME-69306 DNA Replication XP_046668646.1 P25867 R-DME-69618 Mitotic Spindle Checkpoint XP_046668646.1 P25867 R-DME-69620 Cell Cycle Checkpoints XP_046668646.1 P25867 R-DME-72766 Translation XP_046668646.1 P25867 R-DME-73857 RNA Polymerase II Transcription XP_046668646.1 P25867 R-DME-73887 Death Receptor Signaling XP_046668646.1 P25867 R-DME-74160 Gene expression (Transcription) XP_046668646.1 P25867 R-DME-75893 TNF signaling XP_046668646.1 P25867 R-DME-8852135 Protein ubiquitination XP_046668646.1 P25867 R-DME-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes XP_046668646.1 P25867 R-DME-8866654 E3 ubiquitin ligases ubiquitinate target proteins XP_046668646.1 P25867 R-DME-8951664 Neddylation XP_046668646.1 P25867 R-DME-8953897 Cellular responses to stimuli XP_046668646.1 P25867 R-DME-9006936 Signaling by TGFB family members XP_046668646.1 P25867 R-DME-9033241 Peroxisomal protein import XP_046668646.1 P25867 R-DME-9609507 Protein localization XP_046668646.1 P25867 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046668646.1 P25867 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046668646.1 P25867 R-DME-9948299 Ribosome-associated quality control XP_046668646.1 P25867 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046668646.1 P25867 R-DME-9954716 ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA XP_046670408.1 Q24439 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046670408.1 Q24439 R-DME-1430728 Metabolism XP_046670408.1 Q24439 R-DME-1592230 Mitochondrial biogenesis XP_046670408.1 Q24439 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046670408.1 Q24439 R-DME-1852241 Organelle biogenesis and maintenance XP_046670408.1 Q24439 R-DME-392499 Metabolism of proteins XP_046670408.1 Q24439 R-DME-8949613 Cristae formation XP_046670408.1 Q24439 R-DME-9837999 Mitochondrial protein degradation XP_046667437.1 Q9VF86 R-DME-392499 Metabolism of proteins XP_046667437.1 Q9VF86 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046667437.1 Q9VF86 R-DME-446203 Asparagine N-linked glycosylation XP_046667437.1 Q9VF86 R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine XP_046667437.1 Q9VF86 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046667437.1 Q9VF86 R-DME-597592 Post-translational protein modification XP_046668408.1 Q9VFC2 R-DME-109582 Hemostasis XP_046668408.1 Q9VFC2 R-DME-114608 Platelet degranulation XP_046668408.1 Q9VFC2 R-DME-1474244 Extracellular matrix organization XP_046668408.1 Q9VFC2 R-DME-1474290 Collagen formation XP_046668408.1 Q9VFC2 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046668408.1 Q9VFC2 R-DME-168249 Innate Immune System XP_046668408.1 Q9VFC2 R-DME-168256 Immune System XP_046668408.1 Q9VFC2 R-DME-212436 Generic Transcription Pathway XP_046668408.1 Q9VFC2 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046668408.1 Q9VFC2 R-DME-392499 Metabolism of proteins XP_046668408.1 Q9VFC2 R-DME-597592 Post-translational protein modification XP_046668408.1 Q9VFC2 R-DME-6798695 Neutrophil degranulation XP_046668408.1 Q9VFC2 R-DME-73857 RNA Polymerase II Transcription XP_046668408.1 Q9VFC2 R-DME-74160 Gene expression (Transcription) XP_046668408.1 Q9VFC2 R-DME-76002 Platelet activation, signaling and aggregation XP_046668408.1 Q9VFC2 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046668408.1 Q9VFC2 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046668408.1 Q9VFC2 R-DME-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes XP_046668408.1 Q9VFC2 R-DME-8957275 Post-translational protein phosphorylation XP_046668408.1 Q9VFC2 R-DME-9686114 Non-canonical inflammasome activation XP_046668408.1 Q9VFC2 R-DME-9855719 Regulation of FXIIa and plasma kallikrein activity XP_046668408.1 Q9VFC2 R-DME-9948001 CASP4 inflammasome assembly XP_046668408.1 Q9VFC2 R-DME-9970672 FXIIa activates plasma kallikrein-kinin system XP_046669848.1 Q9VF33 R-DME-392499 Metabolism of proteins XP_046669848.1 Q9VF33 R-DME-446203 Asparagine N-linked glycosylation XP_046669848.1 Q9VF33 R-DME-597592 Post-translational protein modification XP_046669848.1 Q9VF33 R-DME-948021 Transport to the Golgi and subsequent modification XP_046669848.1 Q9VF33 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046669848.1 Q9VF33 R-DME-975578 Reactions specific to the complex N-glycan synthesis pathway XP_046661202.1 Q9VF27 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046661202.1 Q9VF27 R-DME-1430728 Metabolism XP_046661202.1 Q9VF27 R-DME-611105 Respiratory electron transport XP_046661202.1 Q9VF27 R-DME-6799198 Complex I biogenesis XP_046658205.1 Q9VF10 R-DME-1280218 Adaptive Immune System XP_046658205.1 Q9VF10 R-DME-1640170 Cell Cycle XP_046658205.1 Q9VF10 R-DME-168256 Immune System XP_046658205.1 Q9VF10 R-DME-392499 Metabolism of proteins XP_046658205.1 Q9VF10 R-DME-453274 Mitotic G2-G2/M phases XP_046658205.1 Q9VF10 R-DME-597592 Post-translational protein modification XP_046658205.1 Q9VF10 R-DME-69275 G2/M Transition XP_046658205.1 Q9VF10 R-DME-69278 Cell Cycle, Mitotic XP_046658205.1 Q9VF10 R-DME-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis XP_046658205.1 Q9VF10 R-DME-8951664 Neddylation XP_046658205.1 Q9VF10 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046658205.1 Q9VF10 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046663921.1 Q8INB9 R-DME-109582 Hemostasis XP_046663921.1 Q8INB9 R-DME-109704 PI3K Cascade XP_046663921.1 Q8INB9 R-DME-110478 Insulin signaling pathway XP_046663921.1 Q8INB9 R-DME-110523 TOR signaling pathway XP_046663921.1 Q8INB9 R-DME-110526 Insulin receptor mediated signaling XP_046663921.1 Q8INB9 R-DME-112399 IRS-mediated signalling XP_046663921.1 Q8INB9 R-DME-1227986 Signaling by ERBB2 XP_046663921.1 Q8INB9 R-DME-1257604 PIP3 activates AKT signaling XP_046663921.1 Q8INB9 R-DME-1266738 Developmental Biology XP_046663921.1 Q8INB9 R-DME-1280215 Cytokine Signaling in Immune system XP_046663921.1 Q8INB9 R-DME-1280218 Adaptive Immune System XP_046663921.1 Q8INB9 R-DME-1358803 Downregulation of ERBB2:ERBB3 signaling XP_046663921.1 Q8INB9 R-DME-1430728 Metabolism XP_046663921.1 Q8INB9 R-DME-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation XP_046663921.1 Q8INB9 R-DME-157118 Signaling by NOTCH XP_046663921.1 Q8INB9 R-DME-162582 Signal Transduction XP_046663921.1 Q8INB9 R-DME-1640170 Cell Cycle XP_046663921.1 Q8INB9 R-DME-165158 Activation of AKT2 XP_046663921.1 Q8INB9 R-DME-165159 MTOR signalling XP_046663921.1 Q8INB9 R-DME-165181 Inhibition of TSC complex formation by AKT (PKB) XP_046663921.1 Q8INB9 R-DME-168256 Immune System XP_046663921.1 Q8INB9 R-DME-186712 Regulation of beta-cell development XP_046663921.1 Q8INB9 R-DME-194138 Signaling by VEGF XP_046663921.1 Q8INB9 R-DME-195721 Signaling by WNT XP_046663921.1 Q8INB9 R-DME-196854 Metabolism of vitamins and cofactors XP_046663921.1 Q8INB9 R-DME-198323 AKT phosphorylates targets in the cytosol XP_046663921.1 Q8INB9 R-DME-198693 AKT phosphorylates targets in the nucleus XP_046663921.1 Q8INB9 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046663921.1 Q8INB9 R-DME-199991 Membrane Trafficking XP_046663921.1 Q8INB9 R-DME-201681 TCF dependent signaling in response to WNT XP_046663921.1 Q8INB9 R-DME-202131 Metabolism of nitric oxide: NOS3 activation and regulation XP_046663921.1 Q8INB9 R-DME-203615 eNOS activation XP_046663921.1 Q8INB9 R-DME-210745 Regulation of gene expression in beta cells XP_046663921.1 Q8INB9 R-DME-211163 AKT-mediated inactivation of FOXO1A XP_046663921.1 Q8INB9 R-DME-212436 Generic Transcription Pathway XP_046663921.1 Q8INB9 R-DME-2262752 Cellular responses to stress XP_046663921.1 Q8INB9 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046663921.1 Q8INB9 R-DME-2428924 IGF1R signaling cascade XP_046663921.1 Q8INB9 R-DME-2428928 IRS-related events triggered by IGF1R XP_046663921.1 Q8INB9 R-DME-354192 Integrin signaling XP_046663921.1 Q8INB9 R-DME-3700989 Transcriptional Regulation by TP53 XP_046663921.1 Q8INB9 R-DME-372790 Signaling by GPCR XP_046663921.1 Q8INB9 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046663921.1 Q8INB9 R-DME-388396 GPCR downstream signalling XP_046663921.1 Q8INB9 R-DME-388841 Regulation of T cell activation by CD28 family XP_046663921.1 Q8INB9 R-DME-389356 Co-stimulation by CD28 XP_046663921.1 Q8INB9 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046663921.1 Q8INB9 R-DME-389513 Co-inhibition by CTLA4 XP_046663921.1 Q8INB9 R-DME-392451 G beta:gamma signalling through PI3Kgamma XP_046663921.1 Q8INB9 R-DME-397795 G-protein beta:gamma signalling XP_046663921.1 Q8INB9 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046663921.1 Q8INB9 R-DME-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA XP_046663921.1 Q8INB9 R-DME-450531 Regulation of mRNA stability by proteins that bind AU-rich elements XP_046663921.1 Q8INB9 R-DME-450604 KSRP (KHSRP) binds and destabilizes mRNA XP_046663921.1 Q8INB9 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046663921.1 Q8INB9 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046663921.1 Q8INB9 R-DME-5252538 Drosophila signaling pathways XP_046663921.1 Q8INB9 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046663921.1 Q8INB9 R-DME-5633007 Regulation of TP53 Activity XP_046663921.1 Q8INB9 R-DME-5653656 Vesicle-mediated transport XP_046663921.1 Q8INB9 R-DME-6804758 Regulation of TP53 Activity through Acetylation XP_046663921.1 Q8INB9 R-DME-6804759 Regulation of TP53 Activity through Association with Co-factors XP_046663921.1 Q8INB9 R-DME-6807070 PTEN Regulation XP_046663921.1 Q8INB9 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046663921.1 Q8INB9 R-DME-69202 Cyclin E associated events during G1/S transition XP_046663921.1 Q8INB9 R-DME-69206 G1/S Transition XP_046663921.1 Q8INB9 R-DME-69242 S Phase XP_046663921.1 Q8INB9 R-DME-69278 Cell Cycle, Mitotic XP_046663921.1 Q8INB9 R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry XP_046663921.1 Q8INB9 R-DME-73857 RNA Polymerase II Transcription XP_046663921.1 Q8INB9 R-DME-74160 Gene expression (Transcription) XP_046663921.1 Q8INB9 R-DME-74751 Insulin receptor signalling cascade XP_046663921.1 Q8INB9 R-DME-74752 Signaling by Insulin receptor XP_046663921.1 Q8INB9 R-DME-76002 Platelet activation, signaling and aggregation XP_046663921.1 Q8INB9 R-DME-76009 Platelet Aggregation (Plug Formation) XP_046663921.1 Q8INB9 R-DME-8863795 Downregulation of ERBB2 signaling XP_046663921.1 Q8INB9 R-DME-8876198 RAB GEFs exchange GTP for GDP on RABs XP_046663921.1 Q8INB9 R-DME-8939211 ESR-mediated signaling XP_046663921.1 Q8INB9 R-DME-8948751 Regulation of PTEN stability and activity XP_046663921.1 Q8INB9 R-DME-8953854 Metabolism of RNA XP_046663921.1 Q8INB9 R-DME-8953897 Cellular responses to stimuli XP_046663921.1 Q8INB9 R-DME-8978934 Metabolism of cofactors XP_046663921.1 Q8INB9 R-DME-9006925 Intracellular signaling by second messengers XP_046663921.1 Q8INB9 R-DME-9006931 Signaling by Nuclear Receptors XP_046663921.1 Q8INB9 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046663921.1 Q8INB9 R-DME-9007101 Rab regulation of trafficking XP_046663921.1 Q8INB9 R-DME-9009391 Extra-nuclear estrogen signaling XP_046663921.1 Q8INB9 R-DME-9013694 Signaling by NOTCH4 XP_046663921.1 Q8INB9 R-DME-9604323 Negative regulation of NOTCH4 signaling XP_046663921.1 Q8INB9 R-DME-9607240 FLT3 Signaling XP_046663921.1 Q8INB9 R-DME-9614085 FOXO-mediated transcription XP_046663921.1 Q8INB9 R-DME-9614399 Regulation of localization of FOXO transcription factors XP_046663921.1 Q8INB9 R-DME-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling XP_046663921.1 Q8INB9 R-DME-9711123 Cellular response to chemical stress XP_046663921.1 Q8INB9 R-DME-9730414 MITF-M-regulated melanocyte development XP_046663921.1 Q8INB9 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046663921.1 Q8INB9 R-DME-9841251 Mitochondrial unfolded protein response (UPRmt) XP_046663921.1 Q8INB9 R-DME-9855142 Cellular responses to mechanical stimuli XP_046663921.1 Q8INB9 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046663921.1 Q8INB9 R-DME-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity XP_046663921.1 Q8INB9 R-DME-9860931 Response of endothelial cells to shear stress XP_046665682.1 Q9VEZ5 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046665682.1 Q9VEZ5 R-DME-1169091 Activation of NF-kappaB in B cells XP_046665682.1 Q9VEZ5 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046665682.1 Q9VEZ5 R-DME-1257604 PIP3 activates AKT signaling XP_046665682.1 Q9VEZ5 R-DME-1280215 Cytokine Signaling in Immune system XP_046665682.1 Q9VEZ5 R-DME-1280218 Adaptive Immune System XP_046665682.1 Q9VEZ5 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046665682.1 Q9VEZ5 R-DME-162582 Signal Transduction XP_046665682.1 Q9VEZ5 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046665682.1 Q9VEZ5 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046665682.1 Q9VEZ5 R-DME-166166 MyD88-independent TLR4 cascade XP_046665682.1 Q9VEZ5 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046665682.1 Q9VEZ5 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046665682.1 Q9VEZ5 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046665682.1 Q9VEZ5 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046665682.1 Q9VEZ5 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046665682.1 Q9VEZ5 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046665682.1 Q9VEZ5 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046665682.1 Q9VEZ5 R-DME-168249 Innate Immune System XP_046665682.1 Q9VEZ5 R-DME-168256 Immune System XP_046665682.1 Q9VEZ5 R-DME-168898 Toll-like Receptor Cascades XP_046665682.1 Q9VEZ5 R-DME-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta XP_046665682.1 Q9VEZ5 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046665682.1 Q9VEZ5 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046665682.1 Q9VEZ5 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046665682.1 Q9VEZ5 R-DME-198323 AKT phosphorylates targets in the cytosol XP_046665682.1 Q9VEZ5 R-DME-202403 TCR signaling XP_046665682.1 Q9VEZ5 R-DME-202424 Downstream TCR signaling XP_046665682.1 Q9VEZ5 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046665682.1 Q9VEZ5 R-DME-209459 Imd pathway XP_046665682.1 Q9VEZ5 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046665682.1 Q9VEZ5 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046665682.1 Q9VEZ5 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046665682.1 Q9VEZ5 R-DME-2871837 FCERI mediated NF-kB activation XP_046665682.1 Q9VEZ5 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046665682.1 Q9VEZ5 R-DME-446652 Interleukin-1 family signaling XP_046665682.1 Q9VEZ5 R-DME-449147 Signaling by Interleukins XP_046665682.1 Q9VEZ5 R-DME-5252538 Drosophila signaling pathways XP_046665682.1 Q9VEZ5 R-DME-5357905 Regulation of TNFR1 signaling XP_046665682.1 Q9VEZ5 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046665682.1 Q9VEZ5 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046665682.1 Q9VEZ5 R-DME-5621481 C-type lectin receptors (CLRs) XP_046665682.1 Q9VEZ5 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046665682.1 Q9VEZ5 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046665682.1 Q9VEZ5 R-DME-73887 Death Receptor Signaling XP_046665682.1 Q9VEZ5 R-DME-75893 TNF signaling XP_046665682.1 Q9VEZ5 R-DME-8953897 Cellular responses to stimuli XP_046665682.1 Q9VEZ5 R-DME-9006925 Intracellular signaling by second messengers XP_046665682.1 Q9VEZ5 R-DME-9020702 Interleukin-1 signaling XP_046665682.1 Q9VEZ5 R-DME-913531 Interferon Signaling XP_046665682.1 Q9VEZ5 R-DME-933542 TRAF6 mediated NF-kB activation XP_046665682.1 Q9VEZ5 R-DME-937039 IRAK1 recruits IKK complex XP_046665682.1 Q9VEZ5 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046665682.1 Q9VEZ5 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046665682.1 Q9VEZ5 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046665682.1 Q9VEZ5 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046665682.1 Q9VEZ5 R-DME-9758274 Regulation of NF-kappa B signaling XP_046665682.1 Q9VEZ5 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046665682.1 Q9VEZ5 R-DME-9833482 PKR-mediated signaling XP_046665682.1 Q9VEZ5 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046665682.1 Q9VEZ5 R-DME-9855142 Cellular responses to mechanical stimuli XP_046665682.1 Q9VEZ5 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046665682.1 Q9VEZ5 R-DME-9860931 Response of endothelial cells to shear stress XP_046665682.1 Q9VEZ5 R-DME-9909505 Modulation of host responses by IFN-stimulated genes XP_046688429.1 Q9VEI3 R-DME-1430728 Metabolism XP_046688429.1 Q9VEI3 R-DME-1630316 Glycosaminoglycan metabolism XP_046688429.1 Q9VEI3 R-DME-174362 Transport and metabolism of PAPS XP_046688429.1 Q9VEI3 R-DME-382551 Transport of small molecules XP_046688429.1 Q9VEI3 R-DME-425397 Transport of vitamins, nucleosides, and related molecules XP_046688429.1 Q9VEI3 R-DME-425407 SLC-mediated transmembrane transport XP_046688429.1 Q9VEI3 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046688429.1 Q9VEI3 R-DME-727802 Transport of nucleotide sugars XP_046660554.1 Q9VEE9 R-DME-392499 Metabolism of proteins XP_046660554.1 Q9VEE9 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046660554.1 Q9VEE9 R-DME-446203 Asparagine N-linked glycosylation XP_046660554.1 Q9VEE9 R-DME-597592 Post-translational protein modification XP_046685648.1 Q07407 R-DME-109704 PI3K Cascade XP_046685648.1 Q07407 R-DME-112399 IRS-mediated signalling XP_046685648.1 Q07407 R-DME-1257604 PIP3 activates AKT signaling XP_046685648.1 Q07407 R-DME-1307965 betaKlotho-mediated ligand binding XP_046685648.1 Q07407 R-DME-162582 Signal Transduction XP_046685648.1 Q07407 R-DME-190236 Signaling by FGFR XP_046685648.1 Q07407 R-DME-190239 FGFR3 ligand binding and activation XP_046685648.1 Q07407 R-DME-190241 FGFR2 ligand binding and activation XP_046685648.1 Q07407 R-DME-190322 FGFR4 ligand binding and activation XP_046685648.1 Q07407 R-DME-190371 FGFR3b ligand binding and activation XP_046685648.1 Q07407 R-DME-190372 FGFR3c ligand binding and activation XP_046685648.1 Q07407 R-DME-190375 FGFR2c ligand binding and activation XP_046685648.1 Q07407 R-DME-190377 FGFR2b ligand binding and activation XP_046685648.1 Q07407 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046685648.1 Q07407 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046685648.1 Q07407 R-DME-2428924 IGF1R signaling cascade XP_046685648.1 Q07407 R-DME-2428928 IRS-related events triggered by IGF1R XP_046685648.1 Q07407 R-DME-5654221 Phospholipase C-mediated cascade; FGFR2 XP_046685648.1 Q07407 R-DME-5654227 Phospholipase C-mediated cascade; FGFR3 XP_046685648.1 Q07407 R-DME-5654228 Phospholipase C-mediated cascade; FGFR4 XP_046685648.1 Q07407 R-DME-5654695 PI-3K cascade:FGFR2 XP_046685648.1 Q07407 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046685648.1 Q07407 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046685648.1 Q07407 R-DME-5654700 FRS-mediated FGFR2 signaling XP_046685648.1 Q07407 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046685648.1 Q07407 R-DME-5654706 FRS-mediated FGFR3 signaling XP_046685648.1 Q07407 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046685648.1 Q07407 R-DME-5654710 PI-3K cascade:FGFR3 XP_046685648.1 Q07407 R-DME-5654712 FRS-mediated FGFR4 signaling XP_046685648.1 Q07407 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046685648.1 Q07407 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046685648.1 Q07407 R-DME-5654720 PI-3K cascade:FGFR4 XP_046685648.1 Q07407 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046685648.1 Q07407 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046685648.1 Q07407 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046685648.1 Q07407 R-DME-5654738 Signaling by FGFR2 XP_046685648.1 Q07407 R-DME-5654741 Signaling by FGFR3 XP_046685648.1 Q07407 R-DME-5654743 Signaling by FGFR4 XP_046685648.1 Q07407 R-DME-5673001 RAF/MAP kinase cascade XP_046685648.1 Q07407 R-DME-5683057 MAPK family signaling cascades XP_046685648.1 Q07407 R-DME-5684996 MAPK1/MAPK3 signaling XP_046685648.1 Q07407 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046685648.1 Q07407 R-DME-74751 Insulin receptor signalling cascade XP_046685648.1 Q07407 R-DME-74752 Signaling by Insulin receptor XP_046685648.1 Q07407 R-DME-9006925 Intracellular signaling by second messengers XP_046685648.1 Q07407 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046683068.1 P92177 R-DME-162582 Signal Transduction XP_046683068.1 P92177 R-DME-1640170 Cell Cycle XP_046683068.1 P92177 R-DME-194315 Signaling by Rho GTPases XP_046683068.1 P92177 R-DME-195258 RHO GTPase Effectors XP_046683068.1 P92177 R-DME-199991 Membrane Trafficking XP_046683068.1 P92177 R-DME-2028269 Signaling by Hippo XP_046683068.1 P92177 R-DME-212436 Generic Transcription Pathway XP_046683068.1 P92177 R-DME-2262752 Cellular responses to stress XP_046683068.1 P92177 R-DME-3371453 Regulation of HSF1-mediated heat shock response XP_046683068.1 P92177 R-DME-3371511 HSF1 activation XP_046683068.1 P92177 R-DME-3371556 Cellular response to heat stress XP_046683068.1 P92177 R-DME-3700989 Transcriptional Regulation by TP53 XP_046683068.1 P92177 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046683068.1 P92177 R-DME-390146 Hippo/Warts pathway XP_046683068.1 P92177 R-DME-390150 DS ligand bound to FT receptor XP_046683068.1 P92177 R-DME-432553 Phosphorylation of PER and TIM XP_046683068.1 P92177 R-DME-432626 Circadian Clock pathway XP_046683068.1 P92177 R-DME-5252538 Drosophila signaling pathways XP_046683068.1 P92177 R-DME-5625740 RHO GTPases activate PKNs XP_046683068.1 P92177 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046683068.1 P92177 R-DME-5653656 Vesicle-mediated transport XP_046683068.1 P92177 R-DME-69473 G2/M DNA damage checkpoint XP_046683068.1 P92177 R-DME-69481 G2/M Checkpoints XP_046683068.1 P92177 R-DME-69620 Cell Cycle Checkpoints XP_046683068.1 P92177 R-DME-73857 RNA Polymerase II Transcription XP_046683068.1 P92177 R-DME-74160 Gene expression (Transcription) XP_046683068.1 P92177 R-DME-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex XP_046683068.1 P92177 R-DME-8876198 RAB GEFs exchange GTP for GDP on RABs XP_046683068.1 P92177 R-DME-8953897 Cellular responses to stimuli XP_046683068.1 P92177 R-DME-9007101 Rab regulation of trafficking XP_046683068.1 P92177 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046687199.1 Q9V3L7 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046687199.1 Q9V3L7 R-DME-1430728 Metabolism XP_046687199.1 Q9V3L7 R-DME-611105 Respiratory electron transport XP_046687199.1 Q9V3L7 R-DME-6799198 Complex I biogenesis XP_046673287.1 Q9VE06 R-DME-1500931 Cell-Cell communication XP_046673287.1 Q9VE06 R-DME-446353 Cell-extracellular matrix interactions XP_046673287.1 Q9VE06 R-DME-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components XP_046673287.1 Q9VE06 R-DME-446728 Cell junction organization XP_046662156.1 Q9VE24 R-DME-1430728 Metabolism XP_046662156.1 Q9VE24 R-DME-1630316 Glycosaminoglycan metabolism XP_046662156.1 Q9VE24 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046662156.1 Q9VE24 R-DME-2024096 HS-GAG degradation XP_046662156.1 Q9VE24 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046659687.1 Q24251 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659687.1 Q24251 R-DME-1430728 Metabolism XP_046659687.1 Q24251 R-DME-1592230 Mitochondrial biogenesis XP_046659687.1 Q24251 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046659687.1 Q24251 R-DME-1852241 Organelle biogenesis and maintenance XP_046659687.1 Q24251 R-DME-392499 Metabolism of proteins XP_046659687.1 Q24251 R-DME-8949613 Cristae formation XP_046659687.1 Q24251 R-DME-9837999 Mitochondrial protein degradation XP_046669346.1 P10041 R-DME-157118 Signaling by NOTCH XP_046669346.1 P10041 R-DME-162582 Signal Transduction XP_046669346.1 P10041 R-DME-1980145 Signaling by NOTCH2 XP_046669346.1 P10041 R-DME-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus XP_046668952.1 Q9VDR6 R-DME-1430728 Metabolism XP_046668952.1 Q9VDR6 R-DME-1630316 Glycosaminoglycan metabolism XP_046668952.1 Q9VDR6 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046668952.1 Q9VDR6 R-DME-2022928 HS-GAG biosynthesis XP_046668952.1 Q9VDR6 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046683753.1 P23573 R-DME-1266738 Developmental Biology XP_046683753.1 P23573 R-DME-1538133 G0 and Early G1 XP_046683753.1 P23573 R-DME-1640170 Cell Cycle XP_046683753.1 P23573 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046683753.1 P23573 R-DME-176187 Activation of ATR in response to replication stress XP_046683753.1 P23573 R-DME-176408 Regulation of APC/C activators between G1/S and early anaphase XP_046683753.1 P23573 R-DME-187577 SCF(Skp2)-mediated degradation of p27/p21 XP_046683753.1 P23573 R-DME-212436 Generic Transcription Pathway XP_046683753.1 P23573 R-DME-2262752 Cellular responses to stress XP_046683753.1 P23573 R-DME-2559582 Senescence-Associated Secretory Phenotype (SASP) XP_046683753.1 P23573 R-DME-2559583 Cellular Senescence XP_046683753.1 P23573 R-DME-2559586 DNA Damage/Telomere Stress Induced Senescence XP_046683753.1 P23573 R-DME-3700989 Transcriptional Regulation by TP53 XP_046683753.1 P23573 R-DME-453274 Mitotic G2-G2/M phases XP_046683753.1 P23573 R-DME-453276 Regulation of mitotic cell cycle XP_046683753.1 P23573 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046683753.1 P23573 R-DME-5633007 Regulation of TP53 Activity XP_046683753.1 P23573 R-DME-5693532 DNA Double-Strand Break Repair XP_046683753.1 P23573 R-DME-5693538 Homology Directed Repair XP_046683753.1 P23573 R-DME-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) XP_046683753.1 P23573 R-DME-5693607 Processing of DNA double-strand break ends XP_046683753.1 P23573 R-DME-6791312 TP53 Regulates Transcription of Cell Cycle Genes XP_046683753.1 P23573 R-DME-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest XP_046683753.1 P23573 R-DME-6804756 Regulation of TP53 Activity through Phosphorylation XP_046683753.1 P23573 R-DME-68911 G2 Phase XP_046683753.1 P23573 R-DME-68949 Orc1 removal from chromatin XP_046683753.1 P23573 R-DME-68962 Activation of the pre-replicative complex XP_046683753.1 P23573 R-DME-69002 DNA Replication Pre-Initiation XP_046683753.1 P23573 R-DME-69017 CDK-mediated phosphorylation and removal of Cdc6 XP_046683753.1 P23573 R-DME-69052 Switching of origins to a post-replicative state XP_046683753.1 P23573 R-DME-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes XP_046683753.1 P23573 R-DME-69202 Cyclin E associated events during G1/S transition XP_046683753.1 P23573 R-DME-69206 G1/S Transition XP_046683753.1 P23573 R-DME-69231 Cyclin D associated events in G1 XP_046683753.1 P23573 R-DME-69236 G1 Phase XP_046683753.1 P23573 R-DME-69239 Synthesis of DNA XP_046683753.1 P23573 R-DME-69242 S Phase XP_046683753.1 P23573 R-DME-69278 Cell Cycle, Mitotic XP_046683753.1 P23573 R-DME-69306 DNA Replication XP_046683753.1 P23573 R-DME-69481 G2/M Checkpoints XP_046683753.1 P23573 R-DME-69563 p53-Dependent G1 DNA Damage Response XP_046683753.1 P23573 R-DME-69580 p53-Dependent G1/S DNA damage checkpoint XP_046683753.1 P23573 R-DME-69615 G1/S DNA Damage Checkpoints XP_046683753.1 P23573 R-DME-69620 Cell Cycle Checkpoints XP_046683753.1 P23573 R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry XP_046683753.1 P23573 R-DME-73857 RNA Polymerase II Transcription XP_046683753.1 P23573 R-DME-73894 DNA Repair XP_046683753.1 P23573 R-DME-74160 Gene expression (Transcription) XP_046683753.1 P23573 R-DME-8953897 Cellular responses to stimuli XP_046683753.1 P23573 R-DME-9616222 Transcriptional regulation of granulopoiesis XP_046678812.1 P91634 R-DME-109582 Hemostasis XP_046678812.1 P91634 R-DME-109704 PI3K Cascade XP_046678812.1 P91634 R-DME-110478 Insulin signaling pathway XP_046678812.1 P91634 R-DME-110526 Insulin receptor mediated signaling XP_046678812.1 P91634 R-DME-112399 IRS-mediated signalling XP_046678812.1 P91634 R-DME-114604 GPVI-mediated activation cascade XP_046678812.1 P91634 R-DME-1257604 PIP3 activates AKT signaling XP_046678812.1 P91634 R-DME-1266738 Developmental Biology XP_046678812.1 P91634 R-DME-1280215 Cytokine Signaling in Immune system XP_046678812.1 P91634 R-DME-1280218 Adaptive Immune System XP_046678812.1 P91634 R-DME-1430728 Metabolism XP_046678812.1 P91634 R-DME-1483255 PI Metabolism XP_046678812.1 P91634 R-DME-1483257 Phospholipid metabolism XP_046678812.1 P91634 R-DME-162582 Signal Transduction XP_046678812.1 P91634 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046678812.1 P91634 R-DME-168249 Innate Immune System XP_046678812.1 P91634 R-DME-168256 Immune System XP_046678812.1 P91634 R-DME-186763 Downstream signal transduction XP_046678812.1 P91634 R-DME-186797 Signaling by PDGF XP_046678812.1 P91634 R-DME-194138 Signaling by VEGF XP_046678812.1 P91634 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046678812.1 P91634 R-DME-201556 Signaling by ALK XP_046678812.1 P91634 R-DME-202733 Cell surface interactions at the vascular wall XP_046678812.1 P91634 R-DME-210993 Tie2 Signaling XP_046678812.1 P91634 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046678812.1 P91634 R-DME-2428924 IGF1R signaling cascade XP_046678812.1 P91634 R-DME-2428928 IRS-related events triggered by IGF1R XP_046678812.1 P91634 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046678812.1 P91634 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046678812.1 P91634 R-DME-422475 Axon guidance XP_046678812.1 P91634 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046678812.1 P91634 R-DME-449147 Signaling by Interleukins XP_046678812.1 P91634 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046678812.1 P91634 R-DME-5252538 Drosophila signaling pathways XP_046678812.1 P91634 R-DME-556833 Metabolism of lipids XP_046678812.1 P91634 R-DME-5673001 RAF/MAP kinase cascade XP_046678812.1 P91634 R-DME-5683057 MAPK family signaling cascades XP_046678812.1 P91634 R-DME-5684996 MAPK1/MAPK3 signaling XP_046678812.1 P91634 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046678812.1 P91634 R-DME-74751 Insulin receptor signalling cascade XP_046678812.1 P91634 R-DME-74752 Signaling by Insulin receptor XP_046678812.1 P91634 R-DME-76002 Platelet activation, signaling and aggregation XP_046678812.1 P91634 R-DME-8853659 RET signaling XP_046678812.1 P91634 R-DME-9006925 Intracellular signaling by second messengers XP_046678812.1 P91634 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046678812.1 P91634 R-DME-912631 Regulation of signaling by CBL XP_046678812.1 P91634 R-DME-9675108 Nervous system development XP_046678812.1 P91634 R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers XP_046678812.1 P91634 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046671597.1 O44226 R-DME-112382 Formation of RNA Pol II elongation complex XP_046671597.1 O44226 R-DME-1234174 Cellular response to hypoxia XP_046671597.1 O44226 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046671597.1 O44226 R-DME-1280218 Adaptive Immune System XP_046671597.1 O44226 R-DME-168256 Immune System XP_046671597.1 O44226 R-DME-212436 Generic Transcription Pathway XP_046671597.1 O44226 R-DME-2262752 Cellular responses to stress XP_046671597.1 O44226 R-DME-3700989 Transcriptional Regulation by TP53 XP_046671597.1 O44226 R-DME-392499 Metabolism of proteins XP_046671597.1 O44226 R-DME-597592 Post-translational protein modification XP_046671597.1 O44226 R-DME-674695 RNA Polymerase II Pre-transcription Events XP_046671597.1 O44226 R-DME-6796648 TP53 Regulates Transcription of DNA Repair Genes XP_046671597.1 O44226 R-DME-72766 Translation XP_046671597.1 O44226 R-DME-73857 RNA Polymerase II Transcription XP_046671597.1 O44226 R-DME-74160 Gene expression (Transcription) XP_046671597.1 O44226 R-DME-75955 RNA Polymerase II Transcription Elongation XP_046671597.1 O44226 R-DME-8951664 Neddylation XP_046671597.1 O44226 R-DME-8953897 Cellular responses to stimuli XP_046671597.1 O44226 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046671597.1 O44226 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046671597.1 O44226 R-DME-9948299 Ribosome-associated quality control XP_046671597.1 O44226 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046658207.1 Q9VDD8 R-DME-1227986 Signaling by ERBB2 XP_046658207.1 Q9VDD8 R-DME-1358803 Downregulation of ERBB2:ERBB3 signaling XP_046658207.1 Q9VDD8 R-DME-162582 Signal Transduction XP_046658207.1 Q9VDD8 R-DME-392499 Metabolism of proteins XP_046658207.1 Q9VDD8 R-DME-5688426 Deubiquitination XP_046658207.1 Q9VDD8 R-DME-5689880 Ub-specific processing proteases XP_046658207.1 Q9VDD8 R-DME-597592 Post-translational protein modification XP_046658207.1 Q9VDD8 R-DME-8863795 Downregulation of ERBB2 signaling XP_046658207.1 Q9VDD8 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046670582.1 P91929 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046670582.1 P91929 R-DME-1430728 Metabolism XP_046670582.1 P91929 R-DME-611105 Respiratory electron transport XP_046670582.1 P91929 R-DME-6799198 Complex I biogenesis XP_046664603.1 Q9V3B4 R-DME-109581 Apoptosis XP_046664603.1 Q9V3B4 R-DME-140534 Caspase activation via Death Receptors in the presence of ligand XP_046664603.1 Q9V3B4 R-DME-162582 Signal Transduction XP_046664603.1 Q9V3B4 R-DME-209438 Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046664603.1 Q9V3B4 R-DME-209459 Imd pathway XP_046664603.1 Q9V3B4 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046664603.1 Q9V3B4 R-DME-214397 Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046664603.1 Q9V3B4 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046664603.1 Q9V3B4 R-DME-214411 REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046664603.1 Q9V3B4 R-DME-214416 Phosphorylated REL is cleaved by and dissociates from DREDD XP_046664603.1 Q9V3B4 R-DME-3371378 Regulation by c-FLIP XP_046664603.1 Q9V3B4 R-DME-5213460 RIPK1-mediated regulated necrosis XP_046664603.1 Q9V3B4 R-DME-5218859 Regulated Necrosis XP_046664603.1 Q9V3B4 R-DME-5218900 CASP8 activity is inhibited XP_046664603.1 Q9V3B4 R-DME-5252538 Drosophila signaling pathways XP_046664603.1 Q9V3B4 R-DME-5357769 Caspase activation via extrinsic apoptotic signalling pathway XP_046664603.1 Q9V3B4 R-DME-5357801 Programmed Cell Death XP_046664603.1 Q9V3B4 R-DME-5357905 Regulation of TNFR1 signaling XP_046664603.1 Q9V3B4 R-DME-5675482 Regulation of necroptotic cell death XP_046664603.1 Q9V3B4 R-DME-69416 Dimerization of procaspase-8 XP_046664603.1 Q9V3B4 R-DME-73887 Death Receptor Signaling XP_046664603.1 Q9V3B4 R-DME-75893 TNF signaling XP_046667602.1 Q9VD58 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046667602.1 Q9VD58 R-DME-1430728 Metabolism XP_046667602.1 Q9VD58 R-DME-71403 Citric acid cycle (TCA cycle) XP_046674196.1 Q95RA8 R-DME-162582 Signal Transduction XP_046674196.1 Q95RA8 R-DME-2028269 Signaling by Hippo XP_046674196.1 Q95RA8 R-DME-390089 Formation of the Hippo kinase cassette XP_046674196.1 Q95RA8 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046674196.1 Q95RA8 R-DME-390146 Hippo/Warts pathway XP_046674196.1 Q95RA8 R-DME-390150 DS ligand bound to FT receptor XP_046674196.1 Q95RA8 R-DME-5252538 Drosophila signaling pathways XP_046665988.1 Q9VCT9 R-DME-392499 Metabolism of proteins XP_046665988.1 Q9VCT9 R-DME-5688426 Deubiquitination XP_046665988.1 Q9VCT9 R-DME-5689880 Ub-specific processing proteases XP_046665988.1 Q9VCT9 R-DME-597592 Post-translational protein modification XP_046687181.1 Q9VCR6 R-DME-162582 Signal Transduction XP_046687181.1 Q9VCR6 R-DME-2028269 Signaling by Hippo XP_046687181.1 Q9VCR6 R-DME-390089 Formation of the Hippo kinase cassette XP_046687181.1 Q9VCR6 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046687181.1 Q9VCR6 R-DME-390146 Hippo/Warts pathway XP_046687181.1 Q9VCR6 R-DME-390150 DS ligand bound to FT receptor XP_046687181.1 Q9VCR6 R-DME-5252538 Drosophila signaling pathways XP_046662759.1 Q9VCN6 R-DME-1280218 Adaptive Immune System XP_046662759.1 Q9VCN6 R-DME-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components XP_046662759.1 Q9VCN6 R-DME-141430 Inactivation of APC/C via direct inhibition of the APC/C complex XP_046662759.1 Q9VCN6 R-DME-1640170 Cell Cycle XP_046662759.1 Q9VCN6 R-DME-168256 Immune System XP_046662759.1 Q9VCN6 R-DME-174048 APC/C:Cdc20 mediated degradation of Cyclin B XP_046662759.1 Q9VCN6 R-DME-174084 Autodegradation of Cdh1 by Cdh1:APC/C XP_046662759.1 Q9VCN6 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046662759.1 Q9VCN6 R-DME-174154 APC/C:Cdc20 mediated degradation of Securin XP_046662759.1 Q9VCN6 R-DME-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 XP_046662759.1 Q9VCN6 R-DME-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A XP_046662759.1 Q9VCN6 R-DME-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase XP_046662759.1 Q9VCN6 R-DME-176408 Regulation of APC/C activators between G1/S and early anaphase XP_046662759.1 Q9VCN6 R-DME-176409 APC/C:Cdc20 mediated degradation of mitotic proteins XP_046662759.1 Q9VCN6 R-DME-176412 Phosphorylation of the APC/C XP_046662759.1 Q9VCN6 R-DME-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins XP_046662759.1 Q9VCN6 R-DME-179409 APC-Cdc20 mediated degradation of Nek2A XP_046662759.1 Q9VCN6 R-DME-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint XP_046662759.1 Q9VCN6 R-DME-2262752 Cellular responses to stress XP_046662759.1 Q9VCN6 R-DME-2467813 Separation of Sister Chromatids XP_046662759.1 Q9VCN6 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046662759.1 Q9VCN6 R-DME-2559582 Senescence-Associated Secretory Phenotype (SASP) XP_046662759.1 Q9VCN6 R-DME-2559583 Cellular Senescence XP_046662759.1 Q9VCN6 R-DME-453276 Regulation of mitotic cell cycle XP_046662759.1 Q9VCN6 R-DME-68867 Assembly of the pre-replicative complex XP_046662759.1 Q9VCN6 R-DME-68882 Mitotic Anaphase XP_046662759.1 Q9VCN6 R-DME-68886 M Phase XP_046662759.1 Q9VCN6 R-DME-69002 DNA Replication Pre-Initiation XP_046662759.1 Q9VCN6 R-DME-69017 CDK-mediated phosphorylation and removal of Cdc6 XP_046662759.1 Q9VCN6 R-DME-69052 Switching of origins to a post-replicative state XP_046662759.1 Q9VCN6 R-DME-69239 Synthesis of DNA XP_046662759.1 Q9VCN6 R-DME-69242 S Phase XP_046662759.1 Q9VCN6 R-DME-69278 Cell Cycle, Mitotic XP_046662759.1 Q9VCN6 R-DME-69306 DNA Replication XP_046662759.1 Q9VCN6 R-DME-69618 Mitotic Spindle Checkpoint XP_046662759.1 Q9VCN6 R-DME-69620 Cell Cycle Checkpoints XP_046662759.1 Q9VCN6 R-DME-8953897 Cellular responses to stimuli XP_046662759.1 Q9VCN6 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046662759.1 Q9VCN6 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046667751.1 Q9VCQ7 R-DME-390146 Hippo/Warts pathway XP_046667751.1 Q9VCQ7 R-DME-390150 DS ligand bound to FT receptor XP_046667751.1 Q9VCQ7 R-DME-5252538 Drosophila signaling pathways XP_046659046.1 Q24407 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659046.1 Q24407 R-DME-1430728 Metabolism XP_046659046.1 Q24407 R-DME-1592230 Mitochondrial biogenesis XP_046659046.1 Q24407 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046659046.1 Q24407 R-DME-1852241 Organelle biogenesis and maintenance XP_046659046.1 Q24407 R-DME-392499 Metabolism of proteins XP_046659046.1 Q24407 R-DME-8949613 Cristae formation XP_046659046.1 Q24407 R-DME-9837999 Mitochondrial protein degradation XP_046685356.1 Q9VCI5 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046685356.1 Q9VCI5 R-DME-1430728 Metabolism XP_046685356.1 Q9VCI5 R-DME-71403 Citric acid cycle (TCA cycle) XP_046658484.1 O77237 R-DME-1280215 Cytokine Signaling in Immune system XP_046658484.1 O77237 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046658484.1 O77237 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046658484.1 O77237 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046658484.1 O77237 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046658484.1 O77237 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046658484.1 O77237 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046658484.1 O77237 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046658484.1 O77237 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046658484.1 O77237 R-DME-168249 Innate Immune System XP_046658484.1 O77237 R-DME-168256 Immune System XP_046658484.1 O77237 R-DME-168898 Toll-like Receptor Cascades XP_046658484.1 O77237 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046658484.1 O77237 R-DME-446652 Interleukin-1 family signaling XP_046658484.1 O77237 R-DME-449147 Signaling by Interleukins XP_046658484.1 O77237 R-DME-9020702 Interleukin-1 signaling XP_046658484.1 O77237 R-DME-937039 IRAK1 recruits IKK complex XP_046658484.1 O77237 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046658484.1 O77237 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046658484.1 O77237 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046658484.1 O77237 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046674541.1 Q9U9A9 R-DME-110523 TOR signaling pathway XP_046674541.1 Q9U9A9 R-DME-110526 Insulin receptor mediated signaling XP_046674541.1 Q9U9A9 R-DME-5252538 Drosophila signaling pathways XP_046674541.1 Q9VCC9 R-DME-162582 Signal Transduction XP_046674541.1 Q9VCC9 R-DME-1632852 Macroautophagy XP_046674541.1 Q9VCC9 R-DME-165159 MTOR signalling XP_046674541.1 Q9VCC9 R-DME-165181 Inhibition of TSC complex formation by AKT (PKB) XP_046674541.1 Q9VCC9 R-DME-199991 Membrane Trafficking XP_046674541.1 Q9VCC9 R-DME-212436 Generic Transcription Pathway XP_046674541.1 Q9VCC9 R-DME-3700989 Transcriptional Regulation by TP53 XP_046674541.1 Q9VCC9 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046674541.1 Q9VCC9 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046674541.1 Q9VCC9 R-DME-5653656 Vesicle-mediated transport XP_046674541.1 Q9VCC9 R-DME-73857 RNA Polymerase II Transcription XP_046674541.1 Q9VCC9 R-DME-74160 Gene expression (Transcription) XP_046674541.1 Q9VCC9 R-DME-8854214 TBC/RABGAPs XP_046674541.1 Q9VCC9 R-DME-9007101 Rab regulation of trafficking XP_046674541.1 Q9VCC9 R-DME-9612973 Autophagy XP_046683099.1 Q9Y1T2 R-DME-209155 Phosphorylation of AXN and APC XP_046683099.1 Q9Y1T2 R-DME-209159 Assembly of the CI containing complexes XP_046683099.1 Q9Y1T2 R-DME-209190 Phosphorylation of CI XP_046683099.1 Q9Y1T2 R-DME-209214 Phosphorylation of SMO XP_046683099.1 Q9Y1T2 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046683099.1 Q9Y1T2 R-DME-209392 Hedgehog pathway XP_046683099.1 Q9Y1T2 R-DME-209396 Phosphorylation of ARM XP_046683099.1 Q9Y1T2 R-DME-209412 Wingless pathway XP_046683099.1 Q9Y1T2 R-DME-209413 Assembly of the 'destruction complex' XP_046683099.1 Q9Y1T2 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046683099.1 Q9Y1T2 R-DME-209441 WG ligand not bound to FZ receptors XP_046683099.1 Q9Y1T2 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046683099.1 Q9Y1T2 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046683099.1 Q9Y1T2 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046683099.1 Q9Y1T2 R-DME-209469 WG ligand bound to FZ receptors XP_046683099.1 Q9Y1T2 R-DME-216217 Activation of SMO XP_046683099.1 Q9Y1T2 R-DME-432553 Phosphorylation of PER and TIM XP_046683099.1 Q9Y1T2 R-DME-432626 Circadian Clock pathway XP_046683099.1 Q9Y1T2 R-DME-5252538 Drosophila signaling pathways XP_046669756.1 Q9VC96 R-DME-1266695 Interleukin-7 signaling XP_046669756.1 Q9VC96 R-DME-1280215 Cytokine Signaling in Immune system XP_046669756.1 Q9VC96 R-DME-162582 Signal Transduction XP_046669756.1 Q9VC96 R-DME-168256 Immune System XP_046669756.1 Q9VC96 R-DME-194315 Signaling by Rho GTPases XP_046669756.1 Q9VC96 R-DME-3247509 Chromatin modifying enzymes XP_046669756.1 Q9VC96 R-DME-449147 Signaling by Interleukins XP_046669756.1 Q9VC96 R-DME-4839726 Chromatin organization XP_046669756.1 Q9VC96 R-DME-9012999 RHO GTPase cycle XP_046669756.1 Q9VC96 R-DME-9013418 RHOBTB2 GTPase cycle XP_046669756.1 Q9VC96 R-DME-9706574 RHOBTB GTPase Cycle XP_046669756.1 Q9VC96 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046682828.1 P48461 R-DME-1640170 Cell Cycle XP_046682828.1 P48461 R-DME-2500257 Resolution of Sister Chromatid Cohesion XP_046682828.1 P48461 R-DME-432626 Circadian Clock pathway XP_046682828.1 P48461 R-DME-5252538 Drosophila signaling pathways XP_046682828.1 P48461 R-DME-538898 Dephosphorylation of TIM XP_046682828.1 P48461 R-DME-68877 Mitotic Prometaphase XP_046682828.1 P48461 R-DME-68886 M Phase XP_046682828.1 P48461 R-DME-69278 Cell Cycle, Mitotic XP_046682828.1 P48461 R-DME-72187 mRNA 3'-end processing XP_046682828.1 P48461 R-DME-72203 Processing of Capped Intron-Containing Pre-mRNA XP_046682828.1 P48461 R-DME-8953854 Metabolism of RNA XP_046682828.1 P48461 R-DME-9770562 mRNA Polyadenylation XP_046658504.1 Q9VC52 R-DME-1430728 Metabolism XP_046658504.1 Q9VC52 R-DME-189445 Metabolism of porphyrins XP_046658504.1 Q9VC52 R-DME-189451 Heme biosynthesis XP_046687112.1 Q9VC56 R-DME-1280215 Cytokine Signaling in Immune system XP_046687112.1 Q9VC56 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046687112.1 Q9VC56 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046687112.1 Q9VC56 R-DME-166166 MyD88-independent TLR4 cascade XP_046687112.1 Q9VC56 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046687112.1 Q9VC56 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046687112.1 Q9VC56 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046687112.1 Q9VC56 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046687112.1 Q9VC56 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046687112.1 Q9VC56 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046687112.1 Q9VC56 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046687112.1 Q9VC56 R-DME-168249 Innate Immune System XP_046687112.1 Q9VC56 R-DME-168256 Immune System XP_046687112.1 Q9VC56 R-DME-168898 Toll-like Receptor Cascades XP_046687112.1 Q9VC56 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046687112.1 Q9VC56 R-DME-392499 Metabolism of proteins XP_046687112.1 Q9VC56 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046687112.1 Q9VC56 R-DME-446652 Interleukin-1 family signaling XP_046687112.1 Q9VC56 R-DME-449147 Signaling by Interleukins XP_046687112.1 Q9VC56 R-DME-5688426 Deubiquitination XP_046687112.1 Q9VC56 R-DME-5689880 Ub-specific processing proteases XP_046687112.1 Q9VC56 R-DME-597592 Post-translational protein modification XP_046687112.1 Q9VC56 R-DME-9020702 Interleukin-1 signaling XP_046687112.1 Q9VC56 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046687112.1 Q9VC56 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046687112.1 Q9VC56 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046687112.1 Q9VC56 R-DME-9758274 Regulation of NF-kappa B signaling XP_046687112.1 Q9VC56 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046667684.1 Q9VC47 R-DME-1474228 Degradation of the extracellular matrix XP_046667684.1 Q9VC47 R-DME-1474244 Extracellular matrix organization XP_046667684.1 Q9VC47 R-DME-1474290 Collagen formation XP_046667684.1 Q9VC47 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046667684.1 Q9VC47 R-DME-2022090 Assembly of collagen fibrils and other multimeric structures XP_046667684.1 Q9VC47 R-DME-2214320 Anchoring fibril formation XP_046667684.1 Q9VC47 R-DME-2243919 Crosslinking of collagen fibrils XP_046667684.1 P25723 R-DME-1474228 Degradation of the extracellular matrix XP_046667684.1 P25723 R-DME-1474244 Extracellular matrix organization XP_046667684.1 P25723 R-DME-1474290 Collagen formation XP_046667684.1 P25723 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046667684.1 P25723 R-DME-2022090 Assembly of collagen fibrils and other multimeric structures XP_046667684.1 P25723 R-DME-2214320 Anchoring fibril formation XP_046667684.1 P25723 R-DME-2243919 Crosslinking of collagen fibrils XP_046662266.1 Q9VC27 R-DME-1236394 Signaling by ERBB4 XP_046662266.1 Q9VC27 R-DME-1251985 Nuclear signaling by ERBB4 XP_046662266.1 Q9VC27 R-DME-1266738 Developmental Biology XP_046662266.1 Q9VC27 R-DME-162582 Signal Transduction XP_046662266.1 Q9VC27 R-DME-168249 Innate Immune System XP_046662266.1 Q9VC27 R-DME-168256 Immune System XP_046662266.1 Q9VC27 R-DME-2682334 EPH-Ephrin signaling XP_046662266.1 Q9VC27 R-DME-3928665 EPH-ephrin mediated repulsion of cells XP_046662266.1 Q9VC27 R-DME-422475 Axon guidance XP_046662266.1 Q9VC27 R-DME-6798695 Neutrophil degranulation XP_046662266.1 Q9VC27 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046662266.1 Q9VC27 R-DME-9675108 Nervous system development XP_046668702.1 Q9VC03 R-DME-1430728 Metabolism XP_046668702.1 Q9VC03 R-DME-196807 Nicotinate metabolism XP_046668702.1 Q9VC03 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046668702.1 Q9VC03 R-DME-196854 Metabolism of vitamins and cofactors XP_046668699.1 Q9VBZ9 R-DME-1430728 Metabolism XP_046668699.1 Q9VBZ9 R-DME-1630316 Glycosaminoglycan metabolism XP_046668699.1 Q9VBZ9 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046668699.1 Q9VBZ9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046667840.1 Q9VBV8 R-DME-392499 Metabolism of proteins XP_046667840.1 Q9VBV8 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046667840.1 Q9VBV8 R-DME-446203 Asparagine N-linked glycosylation XP_046667840.1 Q9VBV8 R-DME-597592 Post-translational protein modification XP_046658817.1 Q9VBP3 R-DME-1257604 PIP3 activates AKT signaling XP_046658817.1 Q9VBP3 R-DME-162582 Signal Transduction XP_046658817.1 Q9VBP3 R-DME-195721 Signaling by WNT XP_046658817.1 Q9VBP3 R-DME-201681 TCF dependent signaling in response to WNT XP_046658817.1 Q9VBP3 R-DME-4641257 Degradation of AXIN XP_046658817.1 Q9VBP3 R-DME-6807070 PTEN Regulation XP_046658817.1 Q9VBP3 R-DME-8948751 Regulation of PTEN stability and activity XP_046658817.1 Q9VBP3 R-DME-9006925 Intracellular signaling by second messengers XP_046684255.1 Q8MT18 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046684255.1 Q8MT18 R-DME-1430728 Metabolism XP_046684255.1 Q8MT18 R-DME-71403 Citric acid cycle (TCA cycle) XP_046682772.1 A0A0B4LHY5 R-DME-109582 Hemostasis XP_046682772.1 A0A0B4LHY5 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046678157.1 P16371 R-DME-1500931 Cell-Cell communication XP_046678157.1 P16371 R-DME-162582 Signal Transduction XP_046678157.1 P16371 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046678157.1 P16371 R-DME-195721 Signaling by WNT XP_046678157.1 P16371 R-DME-201681 TCF dependent signaling in response to WNT XP_046678157.1 P16371 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046678157.1 P16371 R-DME-209412 Wingless pathway XP_046678157.1 P16371 R-DME-209421 Transcription activation by ARM XP_046678157.1 P16371 R-DME-209441 WG ligand not bound to FZ receptors XP_046678157.1 P16371 R-DME-209469 WG ligand bound to FZ receptors XP_046678157.1 P16371 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046678157.1 P16371 R-DME-418990 Adherens junctions interactions XP_046678157.1 P16371 R-DME-421270 Cell-cell junction organization XP_046678157.1 P16371 R-DME-446728 Cell junction organization XP_046678157.1 P16371 R-DME-4641265 Repression of WNT target genes XP_046678157.1 P16371 R-DME-5252538 Drosophila signaling pathways XP_046678157.1 P16371 R-DME-9759476 Regulation of Homotypic Cell-Cell Adhesion XP_046678157.1 P16371 R-DME-9764265 Regulation of CDH1 Expression and Function XP_046678157.1 P16371 R-DME-9764274 Regulation of Expression and Function of Type I Classical Cadherins XP_046678157.1 P16371 R-DME-9764560 Regulation of CDH1 Gene Transcription XP_046678157.1 P16371 R-DME-9764725 Negative Regulation of CDH1 Gene Transcription XP_046682323.1 P07764 R-DME-109582 Hemostasis XP_046682323.1 P07764 R-DME-114608 Platelet degranulation XP_046682323.1 P07764 R-DME-1430728 Metabolism XP_046682323.1 P07764 R-DME-168249 Innate Immune System XP_046682323.1 P07764 R-DME-168256 Immune System XP_046682323.1 P07764 R-DME-5652084 Fructose metabolism XP_046682323.1 P07764 R-DME-6798695 Neutrophil degranulation XP_046682323.1 P07764 R-DME-70171 Glycolysis XP_046682323.1 P07764 R-DME-70263 Gluconeogenesis XP_046682323.1 P07764 R-DME-70326 Glucose metabolism XP_046682323.1 P07764 R-DME-70350 Fructose catabolism XP_046682323.1 P07764 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682323.1 P07764 R-DME-76002 Platelet activation, signaling and aggregation XP_046682323.1 P07764 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046688298.1 Q9VBC4 R-DME-392499 Metabolism of proteins XP_046688298.1 Q9VBC4 R-DME-5688426 Deubiquitination XP_046688298.1 Q9VBC4 R-DME-5689880 Ub-specific processing proteases XP_046688298.1 Q9VBC4 R-DME-597592 Post-translational protein modification XP_046668160.1 P08985 R-DME-1280218 Adaptive Immune System XP_046668160.1 P08985 R-DME-1500931 Cell-Cell communication XP_046668160.1 P08985 R-DME-162582 Signal Transduction XP_046668160.1 P08985 R-DME-168256 Immune System XP_046668160.1 P08985 R-DME-194315 Signaling by Rho GTPases XP_046668160.1 P08985 R-DME-195258 RHO GTPase Effectors XP_046668160.1 P08985 R-DME-211000 Gene Silencing by RNA XP_046668160.1 P08985 R-DME-212165 Epigenetic regulation of gene expression XP_046668160.1 P08985 R-DME-212300 PRC2 methylates histones and DNA XP_046668160.1 P08985 R-DME-212436 Generic Transcription Pathway XP_046668160.1 P08985 R-DME-2262752 Cellular responses to stress XP_046668160.1 P08985 R-DME-2559580 Oxidative Stress Induced Senescence XP_046668160.1 P08985 R-DME-2559582 Senescence-Associated Secretory Phenotype (SASP) XP_046668160.1 P08985 R-DME-2559583 Cellular Senescence XP_046668160.1 P08985 R-DME-388841 Regulation of T cell activation by CD28 family XP_046668160.1 P08985 R-DME-389948 Co-inhibition by PD-1 XP_046668160.1 P08985 R-DME-418990 Adherens junctions interactions XP_046668160.1 P08985 R-DME-421270 Cell-cell junction organization XP_046668160.1 P08985 R-DME-427359 SIRT1 negatively regulates rRNA expression XP_046668160.1 P08985 R-DME-427413 NoRC negatively regulates rRNA expression XP_046668160.1 P08985 R-DME-446728 Cell junction organization XP_046668160.1 P08985 R-DME-4839726 Chromatin organization XP_046668160.1 P08985 R-DME-5250941 Negative epigenetic regulation of rRNA expression XP_046668160.1 P08985 R-DME-5578749 Transcriptional regulation by small RNAs XP_046668160.1 P08985 R-DME-5625740 RHO GTPases activate PKNs XP_046668160.1 P08985 R-DME-5625886 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 XP_046668160.1 P08985 R-DME-68616 Assembly of the ORC complex at the origin of replication XP_046668160.1 P08985 R-DME-68867 Assembly of the pre-replicative complex XP_046668160.1 P08985 R-DME-69002 DNA Replication Pre-Initiation XP_046668160.1 P08985 R-DME-69306 DNA Replication XP_046668160.1 P08985 R-DME-73772 RNA Polymerase I Promoter Escape XP_046668160.1 P08985 R-DME-73854 RNA Polymerase I Promoter Clearance XP_046668160.1 P08985 R-DME-73857 RNA Polymerase II Transcription XP_046668160.1 P08985 R-DME-73864 RNA Polymerase I Transcription XP_046668160.1 P08985 R-DME-74160 Gene expression (Transcription) XP_046668160.1 P08985 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046668160.1 P08985 R-DME-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function XP_046668160.1 P08985 R-DME-8939211 ESR-mediated signaling XP_046668160.1 P08985 R-DME-8953897 Cellular responses to stimuli XP_046668160.1 P08985 R-DME-9006931 Signaling by Nuclear Receptors XP_046668160.1 P08985 R-DME-9018519 Estrogen-dependent gene expression XP_046668160.1 P08985 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046668160.1 P08985 R-DME-9759476 Regulation of Homotypic Cell-Cell Adhesion XP_046668160.1 P08985 R-DME-9764265 Regulation of CDH1 Expression and Function XP_046668160.1 P08985 R-DME-9764274 Regulation of Expression and Function of Type I Classical Cadherins XP_046668160.1 P08985 R-DME-9764560 Regulation of CDH1 Gene Transcription XP_046668160.1 P08985 R-DME-9764725 Negative Regulation of CDH1 Gene Transcription XP_046668160.1 P08985 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046668160.1 P08985 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046668160.1 P08985 R-DME-9842860 Regulation of endogenous retroelements XP_046668160.1 P08985 R-DME-9843940 Regulation of endogenous retroelements by KRAB-ZFP proteins XP_046668160.1 P08985 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046668160.1 P08985 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046668160.1 P08985 R-DME-9909649 Regulation of PD-L1(CD274) transcription XP_046668160.1 P08985 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046668160.1 P08985 R-DME-9932444 ATP-dependent chromatin remodelers XP_046668160.1 P08985 R-DME-9937848 CHD chromatin remodelers XP_046668160.1 P08985 R-DME-9937850 NuRD complex assembly XP_046668160.1 P08985 R-DME-9940951 Interaction of NuRD complexes with transcription factors XP_046668160.1 P08985 R-DME-9943411 CHD1 and CHD2 subfamily XP_046668160.1 P08985 R-DME-9943962 CHD6, CHD7, CHD8, CHD9 subfamily XP_046668160.1 P08985 R-DME-9943965 CHD3, CHD4, CHD5 subfamily XP_046687565.1 P18168 R-DME-157118 Signaling by NOTCH XP_046687565.1 P18168 R-DME-162582 Signal Transduction XP_046687565.1 P18168 R-DME-194315 Signaling by Rho GTPases XP_046687565.1 P18168 R-DME-1980145 Signaling by NOTCH2 XP_046687565.1 P18168 R-DME-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus XP_046687565.1 P18168 R-DME-9012999 RHO GTPase cycle XP_046687565.1 P18168 R-DME-9013149 RAC1 GTPase cycle XP_046687565.1 P18168 R-DME-9013423 RAC3 GTPase cycle XP_046687565.1 P18168 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046667219.1 P48607 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046667219.1 P48607 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046667219.1 P48607 R-DME-209449 Toll pathway XP_046667219.1 P48607 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046667219.1 P48607 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046667219.1 P48607 R-DME-214862 Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' XP_046667219.1 P48607 R-DME-214863 Adaptor protein complex binds to TL receptor at the plasma membrane XP_046667219.1 P48607 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046667219.1 P48607 R-DME-214874 PLL kinase binds to TUB in the TL receptor 'signalling complex' XP_046667219.1 P48607 R-DME-5252538 Drosophila signaling pathways XP_046685502.1 Q05652 R-DME-1280215 Cytokine Signaling in Immune system XP_046685502.1 Q05652 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046685502.1 Q05652 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046685502.1 Q05652 R-DME-166166 MyD88-independent TLR4 cascade XP_046685502.1 Q05652 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046685502.1 Q05652 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046685502.1 Q05652 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046685502.1 Q05652 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046685502.1 Q05652 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046685502.1 Q05652 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046685502.1 Q05652 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046685502.1 Q05652 R-DME-168249 Innate Immune System XP_046685502.1 Q05652 R-DME-168256 Immune System XP_046685502.1 Q05652 R-DME-168898 Toll-like Receptor Cascades XP_046685502.1 Q05652 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046685502.1 Q05652 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046685502.1 Q05652 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046685502.1 Q05652 R-DME-209449 Toll pathway XP_046685502.1 Q05652 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046685502.1 Q05652 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046685502.1 Q05652 R-DME-214862 Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' XP_046685502.1 Q05652 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046685502.1 Q05652 R-DME-214874 PLL kinase binds to TUB in the TL receptor 'signalling complex' XP_046685502.1 Q05652 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046685502.1 Q05652 R-DME-446652 Interleukin-1 family signaling XP_046685502.1 Q05652 R-DME-448424 Interleukin-17 signaling XP_046685502.1 Q05652 R-DME-449147 Signaling by Interleukins XP_046685502.1 Q05652 R-DME-450294 MAP kinase activation XP_046685502.1 Q05652 R-DME-450302 activated TAK1 mediates p38 MAPK activation XP_046685502.1 Q05652 R-DME-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 XP_046685502.1 Q05652 R-DME-5252538 Drosophila signaling pathways XP_046685502.1 Q05652 R-DME-9020702 Interleukin-1 signaling XP_046685502.1 Q05652 R-DME-937039 IRAK1 recruits IKK complex XP_046685502.1 Q05652 R-DME-937042 IRAK2 mediated activation of TAK1 complex XP_046685502.1 Q05652 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046685502.1 Q05652 R-DME-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex XP_046685502.1 Q05652 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046685502.1 Q05652 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046685502.1 Q05652 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046685502.1 Q05652 R-DME-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation XP_046685502.1 Q05652 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046688375.1 Q9VB23 R-DME-432620 Dephosphorylation of PER XP_046688375.1 Q9VB23 R-DME-432626 Circadian Clock pathway XP_046688375.1 Q9VB23 R-DME-5252538 Drosophila signaling pathways XP_046688375.1 A0A6F7R657 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046688375.1 A0A6F7R657 R-DME-1257604 PIP3 activates AKT signaling XP_046688375.1 A0A6F7R657 R-DME-1280215 Cytokine Signaling in Immune system XP_046688375.1 A0A6F7R657 R-DME-1280218 Adaptive Immune System XP_046688375.1 A0A6F7R657 R-DME-162582 Signal Transduction XP_046688375.1 A0A6F7R657 R-DME-168256 Immune System XP_046688375.1 A0A6F7R657 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046688375.1 A0A6F7R657 R-DME-195721 Signaling by WNT XP_046688375.1 A0A6F7R657 R-DME-196299 Beta-catenin phosphorylation cascade XP_046688375.1 A0A6F7R657 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046688375.1 A0A6F7R657 R-DME-388841 Regulation of T cell activation by CD28 family XP_046688375.1 A0A6F7R657 R-DME-389513 Co-inhibition by CTLA4 XP_046688375.1 A0A6F7R657 R-DME-5673000 RAF activation XP_046688375.1 A0A6F7R657 R-DME-5673001 RAF/MAP kinase cascade XP_046688375.1 A0A6F7R657 R-DME-5675221 Negative regulation of MAPK pathway XP_046688375.1 A0A6F7R657 R-DME-5683057 MAPK family signaling cascades XP_046688375.1 A0A6F7R657 R-DME-5684996 MAPK1/MAPK3 signaling XP_046688375.1 A0A6F7R657 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046688375.1 A0A6F7R657 R-DME-9006925 Intracellular signaling by second messengers XP_046688375.1 A0A6F7R657 R-DME-913531 Interferon Signaling XP_046688375.1 A0A6F7R657 R-DME-9833482 PKR-mediated signaling XP_046667353.1 Q9VAW3 R-DME-392499 Metabolism of proteins XP_046667353.1 Q9VAW3 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046667353.1 Q9VAW3 R-DME-446203 Asparagine N-linked glycosylation XP_046667353.1 Q9VAW3 R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine XP_046667353.1 Q9VAW3 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046667353.1 Q9VAW3 R-DME-597592 Post-translational protein modification XP_046658388.1 P14734 R-DME-162582 Signal Transduction XP_046658388.1 P14734 R-DME-8939211 ESR-mediated signaling XP_046658388.1 P14734 R-DME-9006931 Signaling by Nuclear Receptors XP_046658388.1 P14734 R-DME-9018519 Estrogen-dependent gene expression XP_046683099.1 P91667 R-DME-209155 Phosphorylation of AXN and APC XP_046683099.1 P91667 R-DME-209159 Assembly of the CI containing complexes XP_046683099.1 P91667 R-DME-209190 Phosphorylation of CI XP_046683099.1 P91667 R-DME-209214 Phosphorylation of SMO XP_046683099.1 P91667 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046683099.1 P91667 R-DME-209392 Hedgehog pathway XP_046683099.1 P91667 R-DME-209396 Phosphorylation of ARM XP_046683099.1 P91667 R-DME-209412 Wingless pathway XP_046683099.1 P91667 R-DME-209413 Assembly of the 'destruction complex' XP_046683099.1 P91667 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046683099.1 P91667 R-DME-209441 WG ligand not bound to FZ receptors XP_046683099.1 P91667 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046683099.1 P91667 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046683099.1 P91667 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046683099.1 P91667 R-DME-209469 WG ligand bound to FZ receptors XP_046683099.1 P91667 R-DME-216217 Activation of SMO XP_046683099.1 P91667 R-DME-432553 Phosphorylation of PER and TIM XP_046683099.1 P91667 R-DME-432626 Circadian Clock pathway XP_046683099.1 P91667 R-DME-5252538 Drosophila signaling pathways XP_046683099.1 Q9VAS9 R-DME-109581 Apoptosis XP_046683099.1 Q9VAS9 R-DME-111465 Apoptotic cleavage of cellular proteins XP_046683099.1 Q9VAS9 R-DME-162582 Signal Transduction XP_046683099.1 Q9VAS9 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046683099.1 Q9VAS9 R-DME-195721 Signaling by WNT XP_046683099.1 Q9VAS9 R-DME-196299 Beta-catenin phosphorylation cascade XP_046683099.1 Q9VAS9 R-DME-201681 TCF dependent signaling in response to WNT XP_046683099.1 Q9VAS9 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046683099.1 Q9VAS9 R-DME-392499 Metabolism of proteins XP_046683099.1 Q9VAS9 R-DME-5357801 Programmed Cell Death XP_046683099.1 Q9VAS9 R-DME-5688426 Deubiquitination XP_046683099.1 Q9VAS9 R-DME-5689896 Ovarian tumor domain proteases XP_046683099.1 Q9VAS9 R-DME-597592 Post-translational protein modification XP_046683099.1 Q9VAS9 R-DME-75153 Apoptotic execution phase XP_046682567.1 Q7K5K3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682567.1 Q7K5K3 R-DME-1430728 Metabolism XP_046682567.1 Q7K5K3 R-DME-162582 Signal Transduction XP_046682567.1 Q7K5K3 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046682567.1 Q7K5K3 R-DME-392499 Metabolism of proteins XP_046682567.1 Q7K5K3 R-DME-5362517 Signaling by Retinoic Acid XP_046682567.1 Q7K5K3 R-DME-70268 Pyruvate metabolism XP_046682567.1 Q7K5K3 R-DME-9006931 Signaling by Nuclear Receptors XP_046682567.1 Q7K5K3 R-DME-9837999 Mitochondrial protein degradation XP_046682567.1 Q7K5K3 R-DME-9861559 PDH complex synthesizes acetyl-CoA from PYR XP_046682567.1 Q7K5K3 R-DME-9861718 Regulation of pyruvate metabolism XP_046672373.1 Q9VAJ9 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046672373.1 Q9VAJ9 R-DME-1430728 Metabolism XP_046672373.1 Q9VAJ9 R-DME-382551 Transport of small molecules XP_046672373.1 Q9VAJ9 R-DME-425407 SLC-mediated transmembrane transport XP_046672373.1 Q9VAJ9 R-DME-428643 Organic anion transport by SLC5/17/25 transporters XP_046672373.1 Q9VAJ9 R-DME-611105 Respiratory electron transport XP_046672373.1 Q9VAJ9 R-DME-9856872 Malate-aspartate shuttle XP_046672373.1 Q9VAJ9 R-DME-9955298 SLC-mediated transport of organic anions XP_046662252.1 Q9VAI0 R-DME-392499 Metabolism of proteins XP_046662252.1 Q9VAI0 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046662252.1 Q9VAI0 R-DME-446203 Asparagine N-linked glycosylation XP_046662252.1 Q9VAI0 R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine XP_046662252.1 Q9VAI0 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046662252.1 Q9VAI0 R-DME-597592 Post-translational protein modification XP_046667715.1 O01382 R-DME-109581 Apoptosis XP_046667715.1 O01382 R-DME-109606 Intrinsic Pathway for Apoptosis XP_046667715.1 O01382 R-DME-111459 Activation of caspases through apoptosome-mediated cleavage XP_046667715.1 O01382 R-DME-111461 Cytochrome c-mediated apoptotic response XP_046667715.1 O01382 R-DME-111465 Apoptotic cleavage of cellular proteins XP_046667715.1 O01382 R-DME-111469 SMAC, XIAP-regulated apoptotic response XP_046667715.1 O01382 R-DME-111471 Apoptotic factor-mediated response XP_046667715.1 O01382 R-DME-1280215 Cytokine Signaling in Immune system XP_046667715.1 O01382 R-DME-140342 Apoptosis induced DNA fragmentation XP_046667715.1 O01382 R-DME-140534 Caspase activation via Death Receptors in the presence of ligand XP_046667715.1 O01382 R-DME-162582 Signal Transduction XP_046667715.1 O01382 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046667715.1 O01382 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046667715.1 O01382 R-DME-166166 MyD88-independent TLR4 cascade XP_046667715.1 O01382 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046667715.1 O01382 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046667715.1 O01382 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046667715.1 O01382 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046667715.1 O01382 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046667715.1 O01382 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046667715.1 O01382 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046667715.1 O01382 R-DME-168249 Innate Immune System XP_046667715.1 O01382 R-DME-168256 Immune System XP_046667715.1 O01382 R-DME-168898 Toll-like Receptor Cascades XP_046667715.1 O01382 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046667715.1 O01382 R-DME-2028269 Signaling by Hippo XP_046667715.1 O01382 R-DME-264870 Caspase-mediated cleavage of cytoskeletal proteins XP_046667715.1 O01382 R-DME-3371378 Regulation by c-FLIP XP_046667715.1 O01382 R-DME-351906 Apoptotic cleavage of cell adhesion proteins XP_046667715.1 O01382 R-DME-352238 Breakdown of the nuclear lamina XP_046667715.1 O01382 R-DME-418889 Caspase activation via Dependence Receptors in the absence of ligand XP_046667715.1 O01382 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046667715.1 O01382 R-DME-446652 Interleukin-1 family signaling XP_046667715.1 O01382 R-DME-449147 Signaling by Interleukins XP_046667715.1 O01382 R-DME-5213460 RIPK1-mediated regulated necrosis XP_046667715.1 O01382 R-DME-5218859 Regulated Necrosis XP_046667715.1 O01382 R-DME-5218900 CASP8 activity is inhibited XP_046667715.1 O01382 R-DME-5357769 Caspase activation via extrinsic apoptotic signalling pathway XP_046667715.1 O01382 R-DME-5357801 Programmed Cell Death XP_046667715.1 O01382 R-DME-5357905 Regulation of TNFR1 signaling XP_046667715.1 O01382 R-DME-5675482 Regulation of necroptotic cell death XP_046667715.1 O01382 R-DME-69416 Dimerization of procaspase-8 XP_046667715.1 O01382 R-DME-73887 Death Receptor Signaling XP_046667715.1 O01382 R-DME-75153 Apoptotic execution phase XP_046667715.1 O01382 R-DME-75893 TNF signaling XP_046667715.1 O01382 R-DME-9020702 Interleukin-1 signaling XP_046667715.1 O01382 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046667715.1 O01382 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046667715.1 O01382 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046667715.1 O01382 R-DME-9758274 Regulation of NF-kappa B signaling XP_046667715.1 O01382 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046683154.1 O01666 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046683154.1 O01666 R-DME-1430728 Metabolism XP_046683154.1 O01666 R-DME-1592230 Mitochondrial biogenesis XP_046683154.1 O01666 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046683154.1 O01666 R-DME-1852241 Organelle biogenesis and maintenance XP_046683154.1 O01666 R-DME-392499 Metabolism of proteins XP_046683154.1 O01666 R-DME-8949613 Cristae formation XP_046683154.1 O01666 R-DME-9837999 Mitochondrial protein degradation XP_046660072.1 Q9V407 R-DME-162582 Signal Transduction XP_046660072.1 Q9V407 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046660072.1 Q9V407 R-DME-195721 Signaling by WNT XP_046660072.1 Q9V407 R-DME-196299 Beta-catenin phosphorylation cascade XP_046660072.1 Q9V407 R-DME-201681 TCF dependent signaling in response to WNT XP_046660072.1 Q9V407 R-DME-209155 Phosphorylation of AXN and APC XP_046660072.1 Q9V407 R-DME-209159 Assembly of the CI containing complexes XP_046660072.1 Q9V407 R-DME-209190 Phosphorylation of CI XP_046660072.1 Q9V407 R-DME-209214 Phosphorylation of SMO XP_046660072.1 Q9V407 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046660072.1 Q9V407 R-DME-209392 Hedgehog pathway XP_046660072.1 Q9V407 R-DME-209396 Phosphorylation of ARM XP_046660072.1 Q9V407 R-DME-209412 Wingless pathway XP_046660072.1 Q9V407 R-DME-209413 Assembly of the 'destruction complex' XP_046660072.1 Q9V407 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046660072.1 Q9V407 R-DME-209441 WG ligand not bound to FZ receptors XP_046660072.1 Q9V407 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046660072.1 Q9V407 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046660072.1 Q9V407 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046660072.1 Q9V407 R-DME-209469 WG ligand bound to FZ receptors XP_046660072.1 Q9V407 R-DME-216217 Activation of SMO XP_046660072.1 Q9V407 R-DME-432553 Phosphorylation of PER and TIM XP_046660072.1 Q9V407 R-DME-432626 Circadian Clock pathway XP_046660072.1 Q9V407 R-DME-4641257 Degradation of AXIN XP_046660072.1 Q9V407 R-DME-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane XP_046660072.1 Q9V407 R-DME-5252538 Drosophila signaling pathways XP_046669002.1 Q7K483 R-DME-1430728 Metabolism XP_046669002.1 Q7K483 R-DME-196807 Nicotinate metabolism XP_046669002.1 Q7K483 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046669002.1 Q7K483 R-DME-196854 Metabolism of vitamins and cofactors XP_046683760.1 Q9VA73 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046683760.1 Q9VA73 R-DME-1430728 Metabolism XP_046683760.1 Q9VA73 R-DME-611105 Respiratory electron transport XP_046683760.1 Q9VA73 R-DME-71291 Metabolism of amino acids and derivatives XP_046683760.1 Q9VA73 R-DME-8963693 Aspartate and asparagine metabolism XP_046683760.1 Q9VA73 R-DME-9856872 Malate-aspartate shuttle XP_046673697.1 Q9VA38 R-DME-162582 Signal Transduction XP_046673697.1 Q9VA38 R-DME-2028269 Signaling by Hippo XP_046673697.1 Q9VA38 R-DME-390089 Formation of the Hippo kinase cassette XP_046673697.1 Q9VA38 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046673697.1 Q9VA38 R-DME-390146 Hippo/Warts pathway XP_046673697.1 Q9VA38 R-DME-390150 DS ligand bound to FT receptor XP_046673697.1 Q9VA38 R-DME-390178 DS ligand not bound to FT receptor XP_046673697.1 Q9VA38 R-DME-451806 Phosphorylation-independent inhibition of YKI XP_046673697.1 Q9VA38 R-DME-5252538 Drosophila signaling pathways XP_046667191.1 P48456 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046667191.1 P48456 R-DME-1280218 Adaptive Immune System XP_046667191.1 P48456 R-DME-162582 Signal Transduction XP_046667191.1 P48456 R-DME-168249 Innate Immune System XP_046667191.1 P48456 R-DME-168256 Immune System XP_046667191.1 P48456 R-DME-195721 Signaling by WNT XP_046667191.1 P48456 R-DME-2025928 Calcineurin activates NFAT XP_046667191.1 P48456 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046667191.1 P48456 R-DME-2871809 FCERI mediated Ca+2 mobilization XP_046667191.1 P48456 R-DME-3858494 Beta-catenin independent WNT signaling XP_046667191.1 P48456 R-DME-4086398 Ca2+ pathway XP_046667191.1 P48456 R-DME-5607763 CLEC7A (Dectin-1) induces NFAT activation XP_046667191.1 P48456 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046667191.1 P48456 R-DME-5621481 C-type lectin receptors (CLRs) XP_046667191.1 P48456 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046660752.1 O76324 R-DME-162582 Signal Transduction XP_046660752.1 O76324 R-DME-1640170 Cell Cycle XP_046660752.1 O76324 R-DME-195721 Signaling by WNT XP_046660752.1 O76324 R-DME-201681 TCF dependent signaling in response to WNT XP_046660752.1 O76324 R-DME-201688 WNT mediated activation of DVL XP_046660752.1 O76324 R-DME-209155 Phosphorylation of AXN and APC XP_046660752.1 O76324 R-DME-209159 Assembly of the CI containing complexes XP_046660752.1 O76324 R-DME-209190 Phosphorylation of CI XP_046660752.1 O76324 R-DME-209214 Phosphorylation of SMO XP_046660752.1 O76324 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046660752.1 O76324 R-DME-209392 Hedgehog pathway XP_046660752.1 O76324 R-DME-209396 Phosphorylation of ARM XP_046660752.1 O76324 R-DME-209412 Wingless pathway XP_046660752.1 O76324 R-DME-209413 Assembly of the 'destruction complex' XP_046660752.1 O76324 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046660752.1 O76324 R-DME-209441 WG ligand not bound to FZ receptors XP_046660752.1 O76324 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046660752.1 O76324 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046660752.1 O76324 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046660752.1 O76324 R-DME-209469 WG ligand bound to FZ receptors XP_046660752.1 O76324 R-DME-216217 Activation of SMO XP_046660752.1 O76324 R-DME-390023 Subcellular localisation of D XP_046660752.1 O76324 R-DME-390146 Hippo/Warts pathway XP_046660752.1 O76324 R-DME-390150 DS ligand bound to FT receptor XP_046660752.1 O76324 R-DME-432395 Degradation of TIM XP_046660752.1 O76324 R-DME-432490 Nuclear import of PER and TIM XP_046660752.1 O76324 R-DME-432501 Transcription repression by PER and activation by PDP1 XP_046660752.1 O76324 R-DME-432524 Degradation of PER XP_046660752.1 O76324 R-DME-432553 Phosphorylation of PER and TIM XP_046660752.1 O76324 R-DME-432620 Dephosphorylation of PER XP_046660752.1 O76324 R-DME-432626 Circadian Clock pathway XP_046660752.1 O76324 R-DME-5252538 Drosophila signaling pathways XP_046660752.1 O76324 R-DME-538898 Dephosphorylation of TIM XP_046660752.1 O76324 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046660752.1 O76324 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046660752.1 O76324 R-DME-69615 G1/S DNA Damage Checkpoints XP_046660752.1 O76324 R-DME-69620 Cell Cycle Checkpoints XP_046672107.1 Q9V9Z3 R-DME-1430728 Metabolism XP_046672107.1 Q9V9Z3 R-DME-196854 Metabolism of vitamins and cofactors XP_046672107.1 Q9V9Z3 R-DME-2142789 Ubiquinol biosynthesis XP_046672107.1 Q9V9Z3 R-DME-8978934 Metabolism of cofactors XP_046682471.1 Q6NN09 R-DME-1268020 Mitochondrial protein import XP_046682471.1 Q6NN09 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682471.1 Q6NN09 R-DME-1430728 Metabolism XP_046682471.1 Q6NN09 R-DME-1592230 Mitochondrial biogenesis XP_046682471.1 Q6NN09 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046682471.1 Q6NN09 R-DME-1852241 Organelle biogenesis and maintenance XP_046682471.1 Q6NN09 R-DME-8949613 Cristae formation XP_046682471.1 Q6NN09 R-DME-9609507 Protein localization XP_046677747.1 Q9V9W8 R-DME-162582 Signal Transduction XP_046677747.1 Q9V9W8 R-DME-195721 Signaling by WNT XP_046677747.1 Q9V9W8 R-DME-201681 TCF dependent signaling in response to WNT XP_046677747.1 Q9V9W8 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046677747.1 Q9V9W8 R-DME-209407 Transport of ARM to the nucleus XP_046677747.1 Q9V9W8 R-DME-209412 Wingless pathway XP_046677747.1 Q9V9W8 R-DME-209421 Transcription activation by ARM XP_046677747.1 Q9V9W8 R-DME-209469 WG ligand bound to FZ receptors XP_046677747.1 Q9V9W8 R-DME-5252538 Drosophila signaling pathways XP_046668908.1 P55824 R-DME-162582 Signal Transduction XP_046668908.1 P55824 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046668908.1 P55824 R-DME-194315 Signaling by Rho GTPases XP_046668908.1 P55824 R-DME-212436 Generic Transcription Pathway XP_046668908.1 P55824 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046668908.1 P55824 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046668908.1 P55824 R-DME-392499 Metabolism of proteins XP_046668908.1 P55824 R-DME-5688426 Deubiquitination XP_046668908.1 P55824 R-DME-5689880 Ub-specific processing proteases XP_046668908.1 P55824 R-DME-597592 Post-translational protein modification XP_046668908.1 P55824 R-DME-73857 RNA Polymerase II Transcription XP_046668908.1 P55824 R-DME-74160 Gene expression (Transcription) XP_046668908.1 P55824 R-DME-8852135 Protein ubiquitination XP_046668908.1 P55824 R-DME-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes XP_046668908.1 P55824 R-DME-9006936 Signaling by TGFB family members XP_046668908.1 P55824 R-DME-9012999 RHO GTPase cycle XP_046668908.1 P55824 R-DME-9013420 RHOU GTPase cycle XP_046668908.1 P55824 R-DME-9013424 RHOV GTPase cycle XP_046668908.1 P55824 R-DME-9033241 Peroxisomal protein import XP_046668908.1 P55824 R-DME-9609507 Protein localization XP_046668908.1 P55824 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046671846.1 Q9V393 R-DME-162582 Signal Transduction XP_046671846.1 Q9V393 R-DME-195721 Signaling by WNT XP_046671846.1 Q9V393 R-DME-199991 Membrane Trafficking XP_046671846.1 Q9V393 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046671846.1 Q9V393 R-DME-372790 Signaling by GPCR XP_046671846.1 Q9V393 R-DME-3858494 Beta-catenin independent WNT signaling XP_046671846.1 Q9V393 R-DME-388396 GPCR downstream signalling XP_046671846.1 Q9V393 R-DME-392499 Metabolism of proteins XP_046671846.1 Q9V393 R-DME-4086400 PCP/CE pathway XP_046671846.1 Q9V393 R-DME-418555 G alpha (s) signalling events XP_046671846.1 Q9V393 R-DME-432720 Lysosome Vesicle Biogenesis XP_046671846.1 Q9V393 R-DME-432722 Golgi Associated Vesicle Biogenesis XP_046671846.1 Q9V393 R-DME-5099900 WNT5A-dependent internalization of FZD4 XP_046671846.1 Q9V393 R-DME-5653656 Vesicle-mediated transport XP_046671846.1 Q9V393 R-DME-5673001 RAF/MAP kinase cascade XP_046671846.1 Q9V393 R-DME-5674135 MAP2K and MAPK activation XP_046671846.1 Q9V393 R-DME-5683057 MAPK family signaling cascades XP_046671846.1 Q9V393 R-DME-5684996 MAPK1/MAPK3 signaling XP_046671846.1 Q9V393 R-DME-5688426 Deubiquitination XP_046671846.1 Q9V393 R-DME-5689880 Ub-specific processing proteases XP_046671846.1 Q9V393 R-DME-597592 Post-translational protein modification XP_046671846.1 Q9V393 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046671846.1 Q9V393 R-DME-8856828 Clathrin-mediated endocytosis XP_046671846.1 Q9V393 R-DME-9006936 Signaling by TGFB family members XP_046671846.1 Q9V393 R-DME-9839373 Signaling by TGFBR3 XP_046671846.1 Q9V393 R-DME-9839389 TGFBR3 regulates TGF-beta signaling XP_046673770.1 Q9V9R2 R-DME-1234174 Cellular response to hypoxia XP_046673770.1 Q9V9R2 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046673770.1 Q9V9R2 R-DME-1280218 Adaptive Immune System XP_046673770.1 Q9V9R2 R-DME-168256 Immune System XP_046673770.1 Q9V9R2 R-DME-2262752 Cellular responses to stress XP_046673770.1 Q9V9R2 R-DME-392499 Metabolism of proteins XP_046673770.1 Q9V9R2 R-DME-597592 Post-translational protein modification XP_046673770.1 Q9V9R2 R-DME-72766 Translation XP_046673770.1 Q9V9R2 R-DME-8951664 Neddylation XP_046673770.1 Q9V9R2 R-DME-8953897 Cellular responses to stimuli XP_046673770.1 Q9V9R2 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046673770.1 Q9V9R2 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046673770.1 Q9V9R2 R-DME-9948299 Ribosome-associated quality control XP_046673770.1 Q9V9R2 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046662340.1 Q7KRR5 R-DME-392499 Metabolism of proteins XP_046662340.1 Q7KRR5 R-DME-446203 Asparagine N-linked glycosylation XP_046662340.1 Q7KRR5 R-DME-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle XP_046662340.1 Q7KRR5 R-DME-597592 Post-translational protein modification XP_046678731.1 Q8MLL3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046678731.1 Q8MLL3 R-DME-1430728 Metabolism XP_046678731.1 Q8MLL3 R-DME-611105 Respiratory electron transport XP_046678731.1 Q8MLL3 R-DME-9864848 Complex IV assembly XP_046678825.1 P21914 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046678825.1 P21914 R-DME-1430728 Metabolism XP_046678825.1 P21914 R-DME-71403 Citric acid cycle (TCA cycle) XP_046667303.1 Q7YTY6 R-DME-109582 Hemostasis XP_046667303.1 Q7YTY6 R-DME-114608 Platelet degranulation XP_046667303.1 Q7YTY6 R-DME-1430728 Metabolism XP_046667303.1 Q7YTY6 R-DME-168249 Innate Immune System XP_046667303.1 Q7YTY6 R-DME-168256 Immune System XP_046667303.1 Q7YTY6 R-DME-194002 Glucocorticoid biosynthesis XP_046667303.1 Q7YTY6 R-DME-196071 Metabolism of steroid hormones XP_046667303.1 Q7YTY6 R-DME-199977 ER to Golgi Anterograde Transport XP_046667303.1 Q7YTY6 R-DME-199991 Membrane Trafficking XP_046667303.1 Q7YTY6 R-DME-2022377 Metabolism of Angiotensinogen to Angiotensins XP_046667303.1 Q7YTY6 R-DME-204005 COPII-mediated vesicle transport XP_046667303.1 Q7YTY6 R-DME-2980736 Peptide hormone metabolism XP_046667303.1 Q7YTY6 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046667303.1 Q7YTY6 R-DME-392499 Metabolism of proteins XP_046667303.1 Q7YTY6 R-DME-446203 Asparagine N-linked glycosylation XP_046667303.1 Q7YTY6 R-DME-556833 Metabolism of lipids XP_046667303.1 Q7YTY6 R-DME-5653656 Vesicle-mediated transport XP_046667303.1 Q7YTY6 R-DME-5694530 Cargo concentration in the ER XP_046667303.1 Q7YTY6 R-DME-597592 Post-translational protein modification XP_046667303.1 Q7YTY6 R-DME-6798695 Neutrophil degranulation XP_046667303.1 Q7YTY6 R-DME-76002 Platelet activation, signaling and aggregation XP_046667303.1 Q7YTY6 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046667303.1 Q7YTY6 R-DME-8957275 Post-translational protein phosphorylation XP_046667303.1 Q7YTY6 R-DME-8957322 Metabolism of steroids XP_046667303.1 Q7YTY6 R-DME-948021 Transport to the Golgi and subsequent modification XP_046667303.1 Q7YTY6 R-DME-9748784 Drug ADME XP_046667303.1 Q7YTY6 R-DME-9757110 Prednisone ADME XP_046667303.1 Q7YTY6 R-DME-9769739 Regulation of clotting cascade XP_046667303.1 Q7YTY6 R-DME-9769740 Coagulation pathway XP_046681955.1 Q60GL7 R-DME-392499 Metabolism of proteins XP_046681955.1 Q60GL7 R-DME-446203 Asparagine N-linked glycosylation XP_046681955.1 Q60GL7 R-DME-597592 Post-translational protein modification XP_046681955.1 Q60GL7 R-DME-948021 Transport to the Golgi and subsequent modification XP_046681955.1 Q60GL7 R-DME-964739 N-glycan trimming and elongation in the cis-Golgi XP_046668889.1 Q9XZ08 R-DME-1430728 Metabolism XP_046668889.1 Q9XZ08 R-DME-1630316 Glycosaminoglycan metabolism XP_046668889.1 Q9XZ08 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046668889.1 Q9XZ08 R-DME-2022928 HS-GAG biosynthesis XP_046668889.1 Q9XZ08 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046680183.1 Q8MRE7 R-DME-1430728 Metabolism XP_046680183.1 Q8MRE7 R-DME-1630316 Glycosaminoglycan metabolism XP_046680183.1 Q8MRE7 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046680183.1 Q8MRE7 R-DME-2022928 HS-GAG biosynthesis XP_046680183.1 Q8MRE7 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046684450.1 P20007 R-DME-1430728 Metabolism XP_046684450.1 P20007 R-DME-70263 Gluconeogenesis XP_046684450.1 P20007 R-DME-70326 Glucose metabolism XP_046684450.1 P20007 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046676211.1 A1ZBA1 R-DME-162582 Signal Transduction XP_046676211.1 A1ZBA1 R-DME-193648 NRAGE signals death through JNK XP_046676211.1 A1ZBA1 R-DME-193704 p75 NTR receptor-mediated signalling XP_046676211.1 A1ZBA1 R-DME-194315 Signaling by Rho GTPases XP_046676211.1 A1ZBA1 R-DME-204998 Cell death signalling via NRAGE, NRIF and NADE XP_046676211.1 A1ZBA1 R-DME-372790 Signaling by GPCR XP_046676211.1 A1ZBA1 R-DME-388396 GPCR downstream signalling XP_046676211.1 A1ZBA1 R-DME-416482 G alpha (12/13) signalling events XP_046676211.1 A1ZBA1 R-DME-73887 Death Receptor Signaling XP_046676211.1 A1ZBA1 R-DME-8980692 RHOA GTPase cycle XP_046676211.1 A1ZBA1 R-DME-9012999 RHO GTPase cycle XP_046676211.1 A1ZBA1 R-DME-9013148 CDC42 GTPase cycle XP_046676211.1 A1ZBA1 R-DME-9013149 RAC1 GTPase cycle XP_046676211.1 A1ZBA1 R-DME-9013406 RHOQ GTPase cycle XP_046676211.1 A1ZBA1 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046661310.1 Q7K4Z4 R-DME-209438 Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046661310.1 Q7K4Z4 R-DME-209459 Imd pathway XP_046661310.1 Q7K4Z4 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046661310.1 Q7K4Z4 R-DME-214397 Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046661310.1 Q7K4Z4 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046661310.1 Q7K4Z4 R-DME-214411 REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046661310.1 Q7K4Z4 R-DME-214416 Phosphorylated REL is cleaved by and dissociates from DREDD XP_046661310.1 Q7K4Z4 R-DME-5252538 Drosophila signaling pathways XP_046666003.1 Q7K4D1 R-DME-1280218 Adaptive Immune System XP_046666003.1 Q7K4D1 R-DME-162582 Signal Transduction XP_046666003.1 Q7K4D1 R-DME-168256 Immune System XP_046666003.1 Q7K4D1 R-DME-194315 Signaling by Rho GTPases XP_046666003.1 Q7K4D1 R-DME-9012999 RHO GTPase cycle XP_046666003.1 Q7K4D1 R-DME-9013424 RHOV GTPase cycle XP_046666003.1 Q7K4D1 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046666003.1 Q7K4D1 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046666003.1 Q7K4D1 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046660861.1 Q9V853 R-DME-1280218 Adaptive Immune System XP_046660861.1 Q9V853 R-DME-162582 Signal Transduction XP_046660861.1 Q9V853 R-DME-168256 Immune System XP_046660861.1 Q9V853 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046660861.1 Q9V853 R-DME-195721 Signaling by WNT XP_046660861.1 Q9V853 R-DME-201451 Signaling by BMP XP_046660861.1 Q9V853 R-DME-201681 TCF dependent signaling in response to WNT XP_046660861.1 Q9V853 R-DME-212436 Generic Transcription Pathway XP_046660861.1 Q9V853 R-DME-2173788 Downregulation of TGF-beta receptor signaling XP_046660861.1 Q9V853 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046660861.1 Q9V853 R-DME-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) XP_046660861.1 Q9V853 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046660861.1 Q9V853 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046660861.1 Q9V853 R-DME-3858494 Beta-catenin independent WNT signaling XP_046660861.1 Q9V853 R-DME-392499 Metabolism of proteins XP_046660861.1 Q9V853 R-DME-4086400 PCP/CE pathway XP_046660861.1 Q9V853 R-DME-4608870 Asymmetric localization of PCP proteins XP_046660861.1 Q9V853 R-DME-4641257 Degradation of AXIN XP_046660861.1 Q9V853 R-DME-5358351 Signaling by Hedgehog XP_046660861.1 Q9V853 R-DME-5632684 Hedgehog 'on' state XP_046660861.1 Q9V853 R-DME-5688426 Deubiquitination XP_046660861.1 Q9V853 R-DME-5689880 Ub-specific processing proteases XP_046660861.1 Q9V853 R-DME-597592 Post-translational protein modification XP_046660861.1 Q9V853 R-DME-73857 RNA Polymerase II Transcription XP_046660861.1 Q9V853 R-DME-74160 Gene expression (Transcription) XP_046660861.1 Q9V853 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046660861.1 Q9V853 R-DME-8941858 Regulation of RUNX3 expression and activity XP_046660861.1 Q9V853 R-DME-9006936 Signaling by TGFB family members XP_046660861.1 Q9V853 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046660861.1 Q9V853 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046681367.1 Q9V7W9 R-DME-72187 mRNA 3'-end processing XP_046681367.1 Q9V7W9 R-DME-72203 Processing of Capped Intron-Containing Pre-mRNA XP_046681367.1 Q9V7W9 R-DME-8953854 Metabolism of RNA XP_046681367.1 Q9V7W9 R-DME-9770562 mRNA Polyadenylation XP_046660057.1 Q7K306 R-DME-1266738 Developmental Biology XP_046660057.1 Q7K306 R-DME-1280218 Adaptive Immune System XP_046660057.1 Q7K306 R-DME-1640170 Cell Cycle XP_046660057.1 Q7K306 R-DME-168256 Immune System XP_046660057.1 Q7K306 R-DME-212436 Generic Transcription Pathway XP_046660057.1 Q7K306 R-DME-3214858 RMTs methylate histone arginines XP_046660057.1 Q7K306 R-DME-3247509 Chromatin modifying enzymes XP_046660057.1 Q7K306 R-DME-388841 Regulation of T cell activation by CD28 family XP_046660057.1 Q7K306 R-DME-389948 Co-inhibition by PD-1 XP_046660057.1 Q7K306 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046660057.1 Q7K306 R-DME-4839726 Chromatin organization XP_046660057.1 Q7K306 R-DME-69231 Cyclin D associated events in G1 XP_046660057.1 Q7K306 R-DME-69236 G1 Phase XP_046660057.1 Q7K306 R-DME-69242 S Phase XP_046660057.1 Q7K306 R-DME-69278 Cell Cycle, Mitotic XP_046660057.1 Q7K306 R-DME-73857 RNA Polymerase II Transcription XP_046660057.1 Q7K306 R-DME-74160 Gene expression (Transcription) XP_046660057.1 Q7K306 R-DME-75815 Ubiquitin-dependent degradation of Cyclin D XP_046660057.1 Q7K306 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046660057.1 Q7K306 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046660057.1 Q7K306 R-DME-8934593 Regulation of RUNX1 Expression and Activity XP_046660057.1 Q7K306 R-DME-9616222 Transcriptional regulation of granulopoiesis XP_046660057.1 Q7K306 R-DME-9754119 Drug-mediated inhibition of CDK4/CDK6 activity XP_046660057.1 Q7K306 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046660057.1 Q7K306 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046660057.1 Q7K306 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046664931.1 P48148 R-DME-109582 Hemostasis XP_046664931.1 P48148 R-DME-114604 GPVI-mediated activation cascade XP_046664931.1 P48148 R-DME-1227986 Signaling by ERBB2 XP_046664931.1 P48148 R-DME-1266738 Developmental Biology XP_046664931.1 P48148 R-DME-162582 Signal Transduction XP_046664931.1 P48148 R-DME-166520 Signaling by NTRKs XP_046664931.1 P48148 R-DME-168249 Innate Immune System XP_046664931.1 P48148 R-DME-168256 Immune System XP_046664931.1 P48148 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046664931.1 P48148 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046664931.1 P48148 R-DME-193634 Axonal growth inhibition (RHOA activation) XP_046664931.1 P48148 R-DME-193697 p75NTR regulates axonogenesis XP_046664931.1 P48148 R-DME-193704 p75 NTR receptor-mediated signalling XP_046664931.1 P48148 R-DME-194138 Signaling by VEGF XP_046664931.1 P48148 R-DME-194315 Signaling by Rho GTPases XP_046664931.1 P48148 R-DME-195258 RHO GTPase Effectors XP_046664931.1 P48148 R-DME-195721 Signaling by WNT XP_046664931.1 P48148 R-DME-198203 PI3K/AKT activation XP_046664931.1 P48148 R-DME-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) XP_046664931.1 P48148 R-DME-2682334 EPH-Ephrin signaling XP_046664931.1 P48148 R-DME-350368 Activation of RHO1 by FZ:DSH complex XP_046664931.1 P48148 R-DME-350407 RHO1 GTPase cycle XP_046664931.1 P48148 R-DME-350431 Planar Cell Polarity pathway XP_046664931.1 P48148 R-DME-350480 Activation of non-muscle Myosin II XP_046664931.1 P48148 R-DME-372790 Signaling by GPCR XP_046664931.1 P48148 R-DME-373755 Semaphorin interactions XP_046664931.1 P48148 R-DME-3858494 Beta-catenin independent WNT signaling XP_046664931.1 P48148 R-DME-388396 GPCR downstream signalling XP_046664931.1 P48148 R-DME-392451 G beta:gamma signalling through PI3Kgamma XP_046664931.1 P48148 R-DME-392499 Metabolism of proteins XP_046664931.1 P48148 R-DME-3928662 EPHB-mediated forward signaling XP_046664931.1 P48148 R-DME-3928663 EPHA-mediated growth cone collapse XP_046664931.1 P48148 R-DME-397795 G-protein beta:gamma signalling XP_046664931.1 P48148 R-DME-400685 Sema4D in semaphorin signaling XP_046664931.1 P48148 R-DME-4086400 PCP/CE pathway XP_046664931.1 P48148 R-DME-416482 G alpha (12/13) signalling events XP_046664931.1 P48148 R-DME-416572 Sema4D induced cell migration and growth-cone collapse XP_046664931.1 P48148 R-DME-422475 Axon guidance XP_046664931.1 P48148 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046664931.1 P48148 R-DME-450728 Inhibition of actin polymerization XP_046664931.1 P48148 R-DME-450736 Activation of Downstream Effectors XP_046664931.1 P48148 R-DME-450799 RHO1 signalling XP_046664931.1 P48148 R-DME-5252538 Drosophila signaling pathways XP_046664931.1 P48148 R-DME-5625740 RHO GTPases activate PKNs XP_046664931.1 P48148 R-DME-5625900 RHO GTPases activate CIT XP_046664931.1 P48148 R-DME-5627117 RHO GTPases Activate ROCKs XP_046664931.1 P48148 R-DME-5663220 RHO GTPases Activate Formins XP_046664931.1 P48148 R-DME-5666185 RHO GTPases Activate Rhotekin and Rhophilins XP_046664931.1 P48148 R-DME-5688426 Deubiquitination XP_046664931.1 P48148 R-DME-5689896 Ovarian tumor domain proteases XP_046664931.1 P48148 R-DME-597592 Post-translational protein modification XP_046664931.1 P48148 R-DME-6785631 ERBB2 Regulates Cell Motility XP_046664931.1 P48148 R-DME-6798695 Neutrophil degranulation XP_046664931.1 P48148 R-DME-73887 Death Receptor Signaling XP_046664931.1 P48148 R-DME-76002 Platelet activation, signaling and aggregation XP_046664931.1 P48148 R-DME-8848021 Signaling by PTK6 XP_046664931.1 P48148 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046664931.1 P48148 R-DME-8980692 RHOA GTPase cycle XP_046664931.1 P48148 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046664931.1 P48148 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046664931.1 P48148 R-DME-9006936 Signaling by TGFB family members XP_046664931.1 P48148 R-DME-9012999 RHO GTPase cycle XP_046664931.1 P48148 R-DME-9035034 RHOF GTPase cycle XP_046664931.1 P48148 R-DME-9675108 Nervous system development XP_046664931.1 P48148 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046667734.1 A1ZAA5 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046667734.1 A1ZAA5 R-DME-1430728 Metabolism XP_046667734.1 A1ZAA5 R-DME-611105 Respiratory electron transport XP_046667734.1 A1ZAA5 R-DME-71291 Metabolism of amino acids and derivatives XP_046667734.1 A1ZAA5 R-DME-8963693 Aspartate and asparagine metabolism XP_046667734.1 A1ZAA5 R-DME-9856872 Malate-aspartate shuttle XP_046681044.1 Q7KNS3 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046681044.1 Q7KNS3 R-DME-1169091 Activation of NF-kappaB in B cells XP_046681044.1 Q7KNS3 R-DME-1280215 Cytokine Signaling in Immune system XP_046681044.1 Q7KNS3 R-DME-1280218 Adaptive Immune System XP_046681044.1 Q7KNS3 R-DME-1640170 Cell Cycle XP_046681044.1 Q7KNS3 R-DME-168249 Innate Immune System XP_046681044.1 Q7KNS3 R-DME-168256 Immune System XP_046681044.1 Q7KNS3 R-DME-199991 Membrane Trafficking XP_046681044.1 Q7KNS3 R-DME-202403 TCR signaling XP_046681044.1 Q7KNS3 R-DME-202424 Downstream TCR signaling XP_046681044.1 Q7KNS3 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046681044.1 Q7KNS3 R-DME-2565942 Regulation of PLK1 Activity at G2/M Transition XP_046681044.1 Q7KNS3 R-DME-2871837 FCERI mediated NF-kB activation XP_046681044.1 Q7KNS3 R-DME-392499 Metabolism of proteins XP_046681044.1 Q7KNS3 R-DME-453274 Mitotic G2-G2/M phases XP_046681044.1 Q7KNS3 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046681044.1 Q7KNS3 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046681044.1 Q7KNS3 R-DME-5621481 C-type lectin receptors (CLRs) XP_046681044.1 Q7KNS3 R-DME-5653656 Vesicle-mediated transport XP_046681044.1 Q7KNS3 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046681044.1 Q7KNS3 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046681044.1 Q7KNS3 R-DME-597592 Post-translational protein modification XP_046681044.1 Q7KNS3 R-DME-6811436 COPI-independent Golgi-to-ER retrograde traffic XP_046681044.1 Q7KNS3 R-DME-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic XP_046681044.1 Q7KNS3 R-DME-69275 G2/M Transition XP_046681044.1 Q7KNS3 R-DME-69278 Cell Cycle, Mitotic XP_046681044.1 Q7KNS3 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046681044.1 Q7KNS3 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046681044.1 Q7KNS3 R-DME-69615 G1/S DNA Damage Checkpoints XP_046681044.1 Q7KNS3 R-DME-69620 Cell Cycle Checkpoints XP_046681044.1 Q7KNS3 R-DME-8856688 Golgi-to-ER retrograde transport XP_046681044.1 Q7KNS3 R-DME-8951664 Neddylation XP_046681044.1 Q7KNS3 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046681044.1 Q7KNS3 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046681044.1 Q7KNS3 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046670426.1 Q24307 R-DME-109581 Apoptosis XP_046670426.1 Q24307 R-DME-109606 Intrinsic Pathway for Apoptosis XP_046670426.1 Q24307 R-DME-111458 Formation of apoptosome XP_046670426.1 Q24307 R-DME-111459 Activation of caspases through apoptosome-mediated cleavage XP_046670426.1 Q24307 R-DME-111461 Cytochrome c-mediated apoptotic response XP_046670426.1 Q24307 R-DME-111465 Apoptotic cleavage of cellular proteins XP_046670426.1 Q24307 R-DME-111469 SMAC, XIAP-regulated apoptotic response XP_046670426.1 Q24307 R-DME-111471 Apoptotic factor-mediated response XP_046670426.1 Q24307 R-DME-1257604 PIP3 activates AKT signaling XP_046670426.1 Q24307 R-DME-1500931 Cell-Cell communication XP_046670426.1 Q24307 R-DME-162582 Signal Transduction XP_046670426.1 Q24307 R-DME-195721 Signaling by WNT XP_046670426.1 Q24307 R-DME-201681 TCF dependent signaling in response to WNT XP_046670426.1 Q24307 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046670426.1 Q24307 R-DME-209459 Imd pathway XP_046670426.1 Q24307 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046670426.1 Q24307 R-DME-418990 Adherens junctions interactions XP_046670426.1 Q24307 R-DME-421270 Cell-cell junction organization XP_046670426.1 Q24307 R-DME-446728 Cell junction organization XP_046670426.1 Q24307 R-DME-5213460 RIPK1-mediated regulated necrosis XP_046670426.1 Q24307 R-DME-5218859 Regulated Necrosis XP_046670426.1 Q24307 R-DME-5252538 Drosophila signaling pathways XP_046670426.1 Q24307 R-DME-5357801 Programmed Cell Death XP_046670426.1 Q24307 R-DME-5675482 Regulation of necroptotic cell death XP_046670426.1 Q24307 R-DME-6807070 PTEN Regulation XP_046670426.1 Q24307 R-DME-75153 Apoptotic execution phase XP_046670426.1 Q24307 R-DME-8948747 Regulation of PTEN localization XP_046670426.1 Q24307 R-DME-8948751 Regulation of PTEN stability and activity XP_046670426.1 Q24307 R-DME-9006925 Intracellular signaling by second messengers XP_046670426.1 Q24307 R-DME-9627069 Regulation of the apoptosome activity XP_046670426.1 Q24307 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046675435.1 Q7K569 R-DME-1430728 Metabolism XP_046675435.1 Q7K569 R-DME-1483166 Synthesis of PA XP_046675435.1 Q7K569 R-DME-1483206 Glycerophospholipid biosynthesis XP_046675435.1 Q7K569 R-DME-1483257 Phospholipid metabolism XP_046675435.1 Q7K569 R-DME-163560 Triglyceride catabolism XP_046675435.1 Q7K569 R-DME-556833 Metabolism of lipids XP_046675435.1 Q7K569 R-DME-8979227 Triglyceride metabolism XP_046671682.1 Q6WV20 R-DME-162582 Signal Transduction XP_046671682.1 Q6WV20 R-DME-190236 Signaling by FGFR XP_046671682.1 Q6WV20 R-DME-190239 FGFR3 ligand binding and activation XP_046671682.1 Q6WV20 R-DME-190372 FGFR3c ligand binding and activation XP_046671682.1 Q6WV20 R-DME-392499 Metabolism of proteins XP_046671682.1 Q6WV20 R-DME-5173105 O-linked glycosylation XP_046671682.1 Q6WV20 R-DME-5654741 Signaling by FGFR3 XP_046671682.1 Q6WV20 R-DME-597592 Post-translational protein modification XP_046671682.1 Q6WV20 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046671682.1 Q6WV20 R-DME-913709 O-linked glycosylation of mucins XP_046675165.1 Q8SXU3 R-DME-392499 Metabolism of proteins XP_046675165.1 Q8SXU3 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046675165.1 Q8SXU3 R-DME-446203 Asparagine N-linked glycosylation XP_046675165.1 Q8SXU3 R-DME-446205 Synthesis of GDP-mannose XP_046675165.1 Q8SXU3 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046675165.1 Q8SXU3 R-DME-597592 Post-translational protein modification XP_046685088.1 Q7JYW9 R-DME-1430728 Metabolism XP_046685088.1 Q7JYW9 R-DME-168249 Innate Immune System XP_046685088.1 Q7JYW9 R-DME-168256 Immune System XP_046685088.1 Q7JYW9 R-DME-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein XP_046685088.1 Q7JYW9 R-DME-392499 Metabolism of proteins XP_046685088.1 Q7JYW9 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046685088.1 Q7JYW9 R-DME-446203 Asparagine N-linked glycosylation XP_046685088.1 Q7JYW9 R-DME-446205 Synthesis of GDP-mannose XP_046685088.1 Q7JYW9 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046685088.1 Q7JYW9 R-DME-597592 Post-translational protein modification XP_046685088.1 Q7JYW9 R-DME-6798695 Neutrophil degranulation XP_046685088.1 Q7JYW9 R-DME-70171 Glycolysis XP_046685088.1 Q7JYW9 R-DME-70326 Glucose metabolism XP_046685088.1 Q7JYW9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046674350.1 Q8ML92 R-DME-209159 Assembly of the CI containing complexes XP_046674350.1 Q8ML92 R-DME-209190 Phosphorylation of CI XP_046674350.1 Q8ML92 R-DME-209214 Phosphorylation of SMO XP_046674350.1 Q8ML92 R-DME-209392 Hedgehog pathway XP_046674350.1 Q8ML92 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046674350.1 Q8ML92 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046674350.1 Q8ML92 R-DME-216217 Activation of SMO XP_046674350.1 Q8ML92 R-DME-432553 Phosphorylation of PER and TIM XP_046674350.1 Q8ML92 R-DME-432626 Circadian Clock pathway XP_046674350.1 Q8ML92 R-DME-5252538 Drosophila signaling pathways XP_046670749.1 Q6IDF5 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046670749.1 Q6IDF5 R-DME-1430728 Metabolism XP_046670749.1 Q6IDF5 R-DME-611105 Respiratory electron transport XP_046670749.1 Q6IDF5 R-DME-6799198 Complex I biogenesis XP_046670254.1 Q9V719 R-DME-1257604 PIP3 activates AKT signaling XP_046670254.1 Q9V719 R-DME-1280218 Adaptive Immune System XP_046670254.1 Q9V719 R-DME-162582 Signal Transduction XP_046670254.1 Q9V719 R-DME-168256 Immune System XP_046670254.1 Q9V719 R-DME-194138 Signaling by VEGF XP_046670254.1 Q9V719 R-DME-388841 Regulation of T cell activation by CD28 family XP_046670254.1 Q9V719 R-DME-389356 Co-stimulation by CD28 XP_046670254.1 Q9V719 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046670254.1 Q9V719 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046670254.1 Q9V719 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046670254.1 Q9V719 R-DME-8953897 Cellular responses to stimuli XP_046670254.1 Q9V719 R-DME-9006925 Intracellular signaling by second messengers XP_046670254.1 Q9V719 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046670254.1 Q9V719 R-DME-9855142 Cellular responses to mechanical stimuli XP_046670254.1 Q9V719 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046670254.1 Q9V719 R-DME-9860931 Response of endothelial cells to shear stress XP_046668811.1 Q7KN92 R-DME-1430728 Metabolism XP_046668811.1 Q7KN92 R-DME-1630316 Glycosaminoglycan metabolism XP_046668811.1 Q7KN92 R-DME-1638074 Keratan sulfate/keratin metabolism XP_046668811.1 Q7KN92 R-DME-1660662 Glycosphingolipid metabolism XP_046668811.1 Q7KN92 R-DME-2022854 Keratan sulfate biosynthesis XP_046668811.1 Q7KN92 R-DME-392499 Metabolism of proteins XP_046668811.1 Q7KN92 R-DME-428157 Sphingolipid metabolism XP_046668811.1 Q7KN92 R-DME-446203 Asparagine N-linked glycosylation XP_046668811.1 Q7KN92 R-DME-5173105 O-linked glycosylation XP_046668811.1 Q7KN92 R-DME-556833 Metabolism of lipids XP_046668811.1 Q7KN92 R-DME-597592 Post-translational protein modification XP_046668811.1 Q7KN92 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046668811.1 Q7KN92 R-DME-913709 O-linked glycosylation of mucins XP_046668811.1 Q7KN92 R-DME-948021 Transport to the Golgi and subsequent modification XP_046668811.1 Q7KN92 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046668811.1 Q7KN92 R-DME-975577 N-Glycan antennae elongation XP_046668811.1 Q7KN92 R-DME-9840309 Glycosphingolipid biosynthesis XP_046688546.1 P29845 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046688546.1 P29845 R-DME-1430728 Metabolism XP_046688546.1 P29845 R-DME-2262752 Cellular responses to stress XP_046688546.1 P29845 R-DME-3371453 Regulation of HSF1-mediated heat shock response XP_046688546.1 P29845 R-DME-3371556 Cellular response to heat stress XP_046688546.1 P29845 R-DME-392499 Metabolism of proteins XP_046688546.1 P29845 R-DME-611105 Respiratory electron transport XP_046688546.1 P29845 R-DME-6799198 Complex I biogenesis XP_046688546.1 P29845 R-DME-8953897 Cellular responses to stimuli XP_046688546.1 P29845 R-DME-9837999 Mitochondrial protein degradation XP_046688546.1 P29845 R-DME-9865881 Complex III assembly XP_046672397.1 A1Z9K8 R-DME-112316 Neuronal System XP_046672397.1 A1Z9K8 R-DME-6794361 Neurexins and neuroligins XP_046672397.1 A1Z9K8 R-DME-6794362 Protein-protein interactions at synapses XP_046672276.1 Q7K2G1 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046672276.1 Q7K2G1 R-DME-1169091 Activation of NF-kappaB in B cells XP_046672276.1 Q7K2G1 R-DME-1234174 Cellular response to hypoxia XP_046672276.1 Q7K2G1 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046672276.1 Q7K2G1 R-DME-1236975 Antigen processing-Cross presentation XP_046672276.1 Q7K2G1 R-DME-1236978 Cross-presentation of soluble exogenous antigens (endosomes) XP_046672276.1 Q7K2G1 R-DME-1257604 PIP3 activates AKT signaling XP_046672276.1 Q7K2G1 R-DME-1280215 Cytokine Signaling in Immune system XP_046672276.1 Q7K2G1 R-DME-1280218 Adaptive Immune System XP_046672276.1 Q7K2G1 R-DME-1430728 Metabolism XP_046672276.1 Q7K2G1 R-DME-162582 Signal Transduction XP_046672276.1 Q7K2G1 R-DME-1640170 Cell Cycle XP_046672276.1 Q7K2G1 R-DME-168249 Innate Immune System XP_046672276.1 Q7K2G1 R-DME-168256 Immune System XP_046672276.1 Q7K2G1 R-DME-174084 Autodegradation of Cdh1 by Cdh1:APC/C XP_046672276.1 Q7K2G1 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046672276.1 Q7K2G1 R-DME-174154 APC/C:Cdc20 mediated degradation of Securin XP_046672276.1 Q7K2G1 R-DME-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 XP_046672276.1 Q7K2G1 R-DME-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A XP_046672276.1 Q7K2G1 R-DME-176409 APC/C:Cdc20 mediated degradation of mitotic proteins XP_046672276.1 Q7K2G1 R-DME-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins XP_046672276.1 Q7K2G1 R-DME-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint XP_046672276.1 Q7K2G1 R-DME-187577 SCF(Skp2)-mediated degradation of p27/p21 XP_046672276.1 Q7K2G1 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046672276.1 Q7K2G1 R-DME-195721 Signaling by WNT XP_046672276.1 Q7K2G1 R-DME-201681 TCF dependent signaling in response to WNT XP_046672276.1 Q7K2G1 R-DME-202403 TCR signaling XP_046672276.1 Q7K2G1 R-DME-202424 Downstream TCR signaling XP_046672276.1 Q7K2G1 R-DME-212436 Generic Transcription Pathway XP_046672276.1 Q7K2G1 R-DME-2262752 Cellular responses to stress XP_046672276.1 Q7K2G1 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046672276.1 Q7K2G1 R-DME-2467813 Separation of Sister Chromatids XP_046672276.1 Q7K2G1 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046672276.1 Q7K2G1 R-DME-2871837 FCERI mediated NF-kB activation XP_046672276.1 Q7K2G1 R-DME-350562 Regulation of ornithine decarboxylase (ODC) XP_046672276.1 Q7K2G1 R-DME-351202 Metabolism of polyamines XP_046672276.1 Q7K2G1 R-DME-382551 Transport of small molecules XP_046672276.1 Q7K2G1 R-DME-382556 ABC-family protein mediated transport XP_046672276.1 Q7K2G1 R-DME-3858494 Beta-catenin independent WNT signaling XP_046672276.1 Q7K2G1 R-DME-388841 Regulation of T cell activation by CD28 family XP_046672276.1 Q7K2G1 R-DME-389948 Co-inhibition by PD-1 XP_046672276.1 Q7K2G1 R-DME-392499 Metabolism of proteins XP_046672276.1 Q7K2G1 R-DME-4086400 PCP/CE pathway XP_046672276.1 Q7K2G1 R-DME-446652 Interleukin-1 family signaling XP_046672276.1 Q7K2G1 R-DME-449147 Signaling by Interleukins XP_046672276.1 Q7K2G1 R-DME-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA XP_046672276.1 Q7K2G1 R-DME-450531 Regulation of mRNA stability by proteins that bind AU-rich elements XP_046672276.1 Q7K2G1 R-DME-453274 Mitotic G2-G2/M phases XP_046672276.1 Q7K2G1 R-DME-453276 Regulation of mitotic cell cycle XP_046672276.1 Q7K2G1 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046672276.1 Q7K2G1 R-DME-4608870 Asymmetric localization of PCP proteins XP_046672276.1 Q7K2G1 R-DME-4641257 Degradation of AXIN XP_046672276.1 Q7K2G1 R-DME-4641258 Degradation of DVL XP_046672276.1 Q7K2G1 R-DME-5358346 Hedgehog ligand biogenesis XP_046672276.1 Q7K2G1 R-DME-5358351 Signaling by Hedgehog XP_046672276.1 Q7K2G1 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046672276.1 Q7K2G1 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046672276.1 Q7K2G1 R-DME-5610780 Degradation of GLI1 by the proteasome XP_046672276.1 Q7K2G1 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046672276.1 Q7K2G1 R-DME-5610787 Hedgehog 'off' state XP_046672276.1 Q7K2G1 R-DME-5621481 C-type lectin receptors (CLRs) XP_046672276.1 Q7K2G1 R-DME-5632684 Hedgehog 'on' state XP_046672276.1 Q7K2G1 R-DME-5658442 Regulation of RAS by GAPs XP_046672276.1 Q7K2G1 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046672276.1 Q7K2G1 R-DME-5673001 RAF/MAP kinase cascade XP_046672276.1 Q7K2G1 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046672276.1 Q7K2G1 R-DME-5683057 MAPK family signaling cascades XP_046672276.1 Q7K2G1 R-DME-5684996 MAPK1/MAPK3 signaling XP_046672276.1 Q7K2G1 R-DME-5688426 Deubiquitination XP_046672276.1 Q7K2G1 R-DME-5689603 UCH proteinases XP_046672276.1 Q7K2G1 R-DME-5689880 Ub-specific processing proteases XP_046672276.1 Q7K2G1 R-DME-597592 Post-translational protein modification XP_046672276.1 Q7K2G1 R-DME-6807070 PTEN Regulation XP_046672276.1 Q7K2G1 R-DME-68867 Assembly of the pre-replicative complex XP_046672276.1 Q7K2G1 R-DME-68882 Mitotic Anaphase XP_046672276.1 Q7K2G1 R-DME-68886 M Phase XP_046672276.1 Q7K2G1 R-DME-68949 Orc1 removal from chromatin XP_046672276.1 Q7K2G1 R-DME-69002 DNA Replication Pre-Initiation XP_046672276.1 Q7K2G1 R-DME-69017 CDK-mediated phosphorylation and removal of Cdc6 XP_046672276.1 Q7K2G1 R-DME-69052 Switching of origins to a post-replicative state XP_046672276.1 Q7K2G1 R-DME-69202 Cyclin E associated events during G1/S transition XP_046672276.1 Q7K2G1 R-DME-69206 G1/S Transition XP_046672276.1 Q7K2G1 R-DME-69239 Synthesis of DNA XP_046672276.1 Q7K2G1 R-DME-69242 S Phase XP_046672276.1 Q7K2G1 R-DME-69275 G2/M Transition XP_046672276.1 Q7K2G1 R-DME-69278 Cell Cycle, Mitotic XP_046672276.1 Q7K2G1 R-DME-69306 DNA Replication XP_046672276.1 Q7K2G1 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046672276.1 Q7K2G1 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046672276.1 Q7K2G1 R-DME-69615 G1/S DNA Damage Checkpoints XP_046672276.1 Q7K2G1 R-DME-69620 Cell Cycle Checkpoints XP_046672276.1 Q7K2G1 R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry XP_046672276.1 Q7K2G1 R-DME-71291 Metabolism of amino acids and derivatives XP_046672276.1 Q7K2G1 R-DME-72766 Translation XP_046672276.1 Q7K2G1 R-DME-73857 RNA Polymerase II Transcription XP_046672276.1 Q7K2G1 R-DME-74160 Gene expression (Transcription) XP_046672276.1 Q7K2G1 R-DME-75815 Ubiquitin-dependent degradation of Cyclin D XP_046672276.1 Q7K2G1 R-DME-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis XP_046672276.1 Q7K2G1 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046672276.1 Q7K2G1 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046672276.1 Q7K2G1 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046672276.1 Q7K2G1 R-DME-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs XP_046672276.1 Q7K2G1 R-DME-8939902 Regulation of RUNX2 expression and activity XP_046672276.1 Q7K2G1 R-DME-8941858 Regulation of RUNX3 expression and activity XP_046672276.1 Q7K2G1 R-DME-8948751 Regulation of PTEN stability and activity XP_046672276.1 Q7K2G1 R-DME-8951664 Neddylation XP_046672276.1 Q7K2G1 R-DME-8953854 Metabolism of RNA XP_046672276.1 Q7K2G1 R-DME-8953897 Cellular responses to stimuli XP_046672276.1 Q7K2G1 R-DME-9006925 Intracellular signaling by second messengers XP_046672276.1 Q7K2G1 R-DME-9020702 Interleukin-1 signaling XP_046672276.1 Q7K2G1 R-DME-9711123 Cellular response to chemical stress XP_046672276.1 Q7K2G1 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046672276.1 Q7K2G1 R-DME-9759194 Nuclear events mediated by NFE2L2 XP_046672276.1 Q7K2G1 R-DME-9762114 GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 XP_046672276.1 Q7K2G1 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046672276.1 Q7K2G1 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046672276.1 Q7K2G1 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046672276.1 Q7K2G1 R-DME-9907900 Proteasome assembly XP_046672276.1 Q7K2G1 R-DME-9909396 Circadian clock XP_046672276.1 Q7K2G1 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046672276.1 Q7K2G1 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046672276.1 Q7K2G1 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046672276.1 Q7K2G1 R-DME-9932298 Degradation of CRY and PER proteins XP_046672276.1 Q7K2G1 R-DME-9948299 Ribosome-associated quality control XP_046672276.1 Q7K2G1 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046674398.1 Q6IDH2 R-DME-1430728 Metabolism XP_046674398.1 Q6IDH2 R-DME-196807 Nicotinate metabolism XP_046674398.1 Q6IDH2 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046674398.1 Q6IDH2 R-DME-196854 Metabolism of vitamins and cofactors XP_046660218.1 Q08012 R-DME-109582 Hemostasis XP_046660218.1 Q08012 R-DME-109704 PI3K Cascade XP_046660218.1 Q08012 R-DME-112399 IRS-mediated signalling XP_046660218.1 Q08012 R-DME-112412 SOS-mediated signalling XP_046660218.1 Q08012 R-DME-1227986 Signaling by ERBB2 XP_046660218.1 Q08012 R-DME-1236394 Signaling by ERBB4 XP_046660218.1 Q08012 R-DME-1250347 SHC1 events in ERBB4 signaling XP_046660218.1 Q08012 R-DME-1257604 PIP3 activates AKT signaling XP_046660218.1 Q08012 R-DME-1266738 Developmental Biology XP_046660218.1 Q08012 R-DME-1280215 Cytokine Signaling in Immune system XP_046660218.1 Q08012 R-DME-1280218 Adaptive Immune System XP_046660218.1 Q08012 R-DME-1295596 Spry regulation of FGF signaling XP_046660218.1 Q08012 R-DME-1433557 Signaling by SCF-KIT XP_046660218.1 Q08012 R-DME-1433559 Regulation of KIT signaling XP_046660218.1 Q08012 R-DME-162582 Signal Transduction XP_046660218.1 Q08012 R-DME-166520 Signaling by NTRKs XP_046660218.1 Q08012 R-DME-167044 Signalling to RAS XP_046660218.1 Q08012 R-DME-168249 Innate Immune System XP_046660218.1 Q08012 R-DME-168256 Immune System XP_046660218.1 Q08012 R-DME-177929 Signaling by EGFR XP_046660218.1 Q08012 R-DME-179812 GRB2 events in EGFR signaling XP_046660218.1 Q08012 R-DME-180292 GAB1 signalosome XP_046660218.1 Q08012 R-DME-180336 SHC1 events in EGFR signaling XP_046660218.1 Q08012 R-DME-182971 EGFR downregulation XP_046660218.1 Q08012 R-DME-186763 Downstream signal transduction XP_046660218.1 Q08012 R-DME-186797 Signaling by PDGF XP_046660218.1 Q08012 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046660218.1 Q08012 R-DME-187687 Signalling to ERKs XP_046660218.1 Q08012 R-DME-190236 Signaling by FGFR XP_046660218.1 Q08012 R-DME-194315 Signaling by Rho GTPases XP_046660218.1 Q08012 R-DME-195258 RHO GTPase Effectors XP_046660218.1 Q08012 R-DME-1963640 GRB2 events in ERBB2 signaling XP_046660218.1 Q08012 R-DME-1963642 PI3K events in ERBB2 signaling XP_046660218.1 Q08012 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046660218.1 Q08012 R-DME-199991 Membrane Trafficking XP_046660218.1 Q08012 R-DME-202733 Cell surface interactions at the vascular wall XP_046660218.1 Q08012 R-DME-2029480 Fcgamma receptor (FCGR) dependent phagocytosis XP_046660218.1 Q08012 R-DME-2029482 Regulation of actin dynamics for phagocytic cup formation XP_046660218.1 Q08012 R-DME-210993 Tie2 Signaling XP_046660218.1 Q08012 R-DME-2172127 DAP12 interactions XP_046660218.1 Q08012 R-DME-2179392 EGFR Transactivation by Gastrin XP_046660218.1 Q08012 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046660218.1 Q08012 R-DME-2424491 DAP12 signaling XP_046660218.1 Q08012 R-DME-2428924 IGF1R signaling cascade XP_046660218.1 Q08012 R-DME-2428928 IRS-related events triggered by IGF1R XP_046660218.1 Q08012 R-DME-2428933 SHC-related events triggered by IGF1R XP_046660218.1 Q08012 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046660218.1 Q08012 R-DME-2730905 Role of LAT2/NTAL/LAB on calcium mobilization XP_046660218.1 Q08012 R-DME-2871796 FCERI mediated MAPK activation XP_046660218.1 Q08012 R-DME-2871809 FCERI mediated Ca+2 mobilization XP_046660218.1 Q08012 R-DME-372790 Signaling by GPCR XP_046660218.1 Q08012 R-DME-375165 NCAM signaling for neurite out-growth XP_046660218.1 Q08012 R-DME-388396 GPCR downstream signalling XP_046660218.1 Q08012 R-DME-416476 G alpha (q) signalling events XP_046660218.1 Q08012 R-DME-422475 Axon guidance XP_046660218.1 Q08012 R-DME-449147 Signaling by Interleukins XP_046660218.1 Q08012 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046660218.1 Q08012 R-DME-5653656 Vesicle-mediated transport XP_046660218.1 Q08012 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046660218.1 Q08012 R-DME-5654688 SHC-mediated cascade:FGFR1 XP_046660218.1 Q08012 R-DME-5654689 PI-3K cascade:FGFR1 XP_046660218.1 Q08012 R-DME-5654693 FRS-mediated FGFR1 signaling XP_046660218.1 Q08012 R-DME-5654695 PI-3K cascade:FGFR2 XP_046660218.1 Q08012 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046660218.1 Q08012 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046660218.1 Q08012 R-DME-5654700 FRS-mediated FGFR2 signaling XP_046660218.1 Q08012 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046660218.1 Q08012 R-DME-5654706 FRS-mediated FGFR3 signaling XP_046660218.1 Q08012 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046660218.1 Q08012 R-DME-5654710 PI-3K cascade:FGFR3 XP_046660218.1 Q08012 R-DME-5654712 FRS-mediated FGFR4 signaling XP_046660218.1 Q08012 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046660218.1 Q08012 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046660218.1 Q08012 R-DME-5654720 PI-3K cascade:FGFR4 XP_046660218.1 Q08012 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046660218.1 Q08012 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046660218.1 Q08012 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046660218.1 Q08012 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046660218.1 Q08012 R-DME-5654736 Signaling by FGFR1 XP_046660218.1 Q08012 R-DME-5654738 Signaling by FGFR2 XP_046660218.1 Q08012 R-DME-5654741 Signaling by FGFR3 XP_046660218.1 Q08012 R-DME-5654743 Signaling by FGFR4 XP_046660218.1 Q08012 R-DME-5663213 RHO GTPases Activate WASPs and WAVEs XP_046660218.1 Q08012 R-DME-5673001 RAF/MAP kinase cascade XP_046660218.1 Q08012 R-DME-5683057 MAPK family signaling cascades XP_046660218.1 Q08012 R-DME-5684996 MAPK1/MAPK3 signaling XP_046660218.1 Q08012 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046660218.1 Q08012 R-DME-74749 Signal attenuation XP_046660218.1 Q08012 R-DME-74751 Insulin receptor signalling cascade XP_046660218.1 Q08012 R-DME-74752 Signaling by Insulin receptor XP_046660218.1 Q08012 R-DME-881907 Gastrin-CREB signalling pathway via PKC and MAPK XP_046660218.1 Q08012 R-DME-8853659 RET signaling XP_046660218.1 Q08012 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046660218.1 Q08012 R-DME-8856828 Clathrin-mediated endocytosis XP_046660218.1 Q08012 R-DME-9006925 Intracellular signaling by second messengers XP_046660218.1 Q08012 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660218.1 Q08012 R-DME-9012999 RHO GTPase cycle XP_046660218.1 Q08012 R-DME-9013420 RHOU GTPase cycle XP_046660218.1 Q08012 R-DME-912631 Regulation of signaling by CBL XP_046660218.1 Q08012 R-DME-9607240 FLT3 Signaling XP_046660218.1 Q08012 R-DME-9675108 Nervous system development XP_046660218.1 Q08012 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046660218.1 Q08012 R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers XP_046660218.1 Q08012 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046674956.1 Q95V09 R-DME-209387 Phosphorylation of ARR XP_046674956.1 Q95V09 R-DME-209412 Wingless pathway XP_046674956.1 Q95V09 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046674956.1 Q95V09 R-DME-209469 WG ligand bound to FZ receptors XP_046674956.1 Q95V09 R-DME-209472 Assembly of receptor complex XP_046674956.1 Q95V09 R-DME-5252538 Drosophila signaling pathways XP_046674956.1 A1Z9D7 R-DME-162582 Signal Transduction XP_046674956.1 A1Z9D7 R-DME-195721 Signaling by WNT XP_046674956.1 A1Z9D7 R-DME-201681 TCF dependent signaling in response to WNT XP_046674956.1 A1Z9D7 R-DME-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane XP_046681956.1 Q5BIL9 R-DME-1430728 Metabolism XP_046681956.1 Q5BIL9 R-DME-1630316 Glycosaminoglycan metabolism XP_046681956.1 Q5BIL9 R-DME-1638074 Keratan sulfate/keratin metabolism XP_046681956.1 Q5BIL9 R-DME-168249 Innate Immune System XP_046681956.1 Q5BIL9 R-DME-168256 Immune System XP_046681956.1 Q5BIL9 R-DME-199991 Membrane Trafficking XP_046681956.1 Q5BIL9 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046681956.1 Q5BIL9 R-DME-2022857 Keratan sulfate degradation XP_046681956.1 Q5BIL9 R-DME-432720 Lysosome Vesicle Biogenesis XP_046681956.1 Q5BIL9 R-DME-5653656 Vesicle-mediated transport XP_046681956.1 Q5BIL9 R-DME-6798695 Neutrophil degranulation XP_046681956.1 Q5BIL9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046681961.1 A1Z992 R-DME-1430728 Metabolism XP_046681961.1 A1Z992 R-DME-3322077 Glycogen synthesis XP_046681961.1 A1Z992 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046681961.1 A1Z992 R-DME-8982491 Glycogen metabolism XP_046680363.1 Q9XY35 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046680363.1 Q9XY35 R-DME-1430728 Metabolism XP_046680363.1 Q9XY35 R-DME-611105 Respiratory electron transport XP_046680363.1 Q9XY35 R-DME-9865881 Complex III assembly XP_046682137.1 A0A0B4K765 R-DME-1266738 Developmental Biology XP_046682137.1 A0A0B4K765 R-DME-1430728 Metabolism XP_046682137.1 A0A0B4K765 R-DME-212436 Generic Transcription Pathway XP_046682137.1 A0A0B4K765 R-DME-2262752 Cellular responses to stress XP_046682137.1 A0A0B4K765 R-DME-400206 Regulation of lipid metabolism by PPARalpha XP_046682137.1 A0A0B4K765 R-DME-556833 Metabolism of lipids XP_046682137.1 A0A0B4K765 R-DME-73857 RNA Polymerase II Transcription XP_046682137.1 A0A0B4K765 R-DME-74160 Gene expression (Transcription) XP_046682137.1 A0A0B4K765 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046682137.1 A0A0B4K765 R-DME-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function XP_046682137.1 A0A0B4K765 R-DME-8953897 Cellular responses to stimuli XP_046682137.1 A0A0B4K765 R-DME-9707564 Cytoprotection by HMOX1 XP_046682137.1 A0A0B4K765 R-DME-9711123 Cellular response to chemical stress XP_046682137.1 A0A0B4K765 R-DME-9730414 MITF-M-regulated melanocyte development XP_046682137.1 A0A0B4K765 R-DME-9824594 Regulation of MITF-M-dependent genes involved in apoptosis XP_046682137.1 A0A0B4K765 R-DME-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation XP_046682137.1 A0A0B4K765 R-DME-9856651 MITF-M-dependent gene expression XP_046676097.1 Q6AWJ9 R-DME-109582 Hemostasis XP_046676097.1 Q6AWJ9 R-DME-1266738 Developmental Biology XP_046676097.1 Q6AWJ9 R-DME-1474228 Degradation of the extracellular matrix XP_046676097.1 Q6AWJ9 R-DME-1474244 Extracellular matrix organization XP_046676097.1 Q6AWJ9 R-DME-202733 Cell surface interactions at the vascular wall XP_046676097.1 Q6AWJ9 R-DME-210991 Basigin interactions XP_046676097.1 Q6AWJ9 R-DME-216083 Integrin cell surface interactions XP_046676097.1 Q6AWJ9 R-DME-376176 Signaling by ROBO receptors XP_046676097.1 Q6AWJ9 R-DME-382551 Transport of small molecules XP_046676097.1 Q6AWJ9 R-DME-422475 Axon guidance XP_046676097.1 Q6AWJ9 R-DME-425407 SLC-mediated transmembrane transport XP_046676097.1 Q6AWJ9 R-DME-428542 Regulation of commissural axon pathfinding by SLIT and ROBO XP_046676097.1 Q6AWJ9 R-DME-433692 Proton-coupled monocarboxylate transport XP_046676097.1 Q6AWJ9 R-DME-9675108 Nervous system development XP_046676097.1 Q6AWJ9 R-DME-9748784 Drug ADME XP_046676097.1 Q6AWJ9 R-DME-9749641 Aspirin ADME XP_046676097.1 Q6AWJ9 R-DME-9955298 SLC-mediated transport of organic anions XP_046681950.1 A1Z8R6 R-DME-1430728 Metabolism XP_046681950.1 A1Z8R6 R-DME-1630316 Glycosaminoglycan metabolism XP_046681950.1 A1Z8R6 R-DME-1638074 Keratan sulfate/keratin metabolism XP_046681950.1 A1Z8R6 R-DME-1660662 Glycosphingolipid metabolism XP_046681950.1 A1Z8R6 R-DME-2022854 Keratan sulfate biosynthesis XP_046681950.1 A1Z8R6 R-DME-392499 Metabolism of proteins XP_046681950.1 A1Z8R6 R-DME-428157 Sphingolipid metabolism XP_046681950.1 A1Z8R6 R-DME-5173105 O-linked glycosylation XP_046681950.1 A1Z8R6 R-DME-556833 Metabolism of lipids XP_046681950.1 A1Z8R6 R-DME-597592 Post-translational protein modification XP_046681950.1 A1Z8R6 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046681950.1 A1Z8R6 R-DME-9033658 Blood group systems biosynthesis XP_046681950.1 A1Z8R6 R-DME-9037629 Lewis blood group biosynthesis XP_046681950.1 A1Z8R6 R-DME-913709 O-linked glycosylation of mucins XP_046681950.1 A1Z8R6 R-DME-9840309 Glycosphingolipid biosynthesis XP_046673358.1 A1Z8N1 R-DME-189200 Cellular hexose transport XP_046673358.1 A1Z8N1 R-DME-382551 Transport of small molecules XP_046673358.1 A1Z8N1 R-DME-425407 SLC-mediated transmembrane transport XP_046661053.1 Q9V3T9 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046661053.1 Q9V3T9 R-DME-1430728 Metabolism XP_046661053.1 Q9V3T9 R-DME-2395516 Electron transport from NADPH to Ferredoxin XP_046671893.1 Q1LZ08 R-DME-110314 Recognition of DNA damage by PCNA-containing replication complex XP_046671893.1 Q1LZ08 R-DME-392499 Metabolism of proteins XP_046671893.1 Q1LZ08 R-DME-5688426 Deubiquitination XP_046671893.1 Q1LZ08 R-DME-5689880 Ub-specific processing proteases XP_046671893.1 Q1LZ08 R-DME-597592 Post-translational protein modification XP_046671893.1 Q1LZ08 R-DME-73893 DNA Damage Bypass XP_046671893.1 Q1LZ08 R-DME-73894 DNA Repair XP_046681132.1 Q7JZK1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046681132.1 Q7JZK1 R-DME-1430728 Metabolism XP_046681132.1 Q7JZK1 R-DME-611105 Respiratory electron transport XP_046681132.1 Q7JZK1 R-DME-6799198 Complex I biogenesis XP_046667254.1 A1Z863 R-DME-1430728 Metabolism XP_046667254.1 A1Z863 R-DME-1630316 Glycosaminoglycan metabolism XP_046667254.1 A1Z863 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046667254.1 A1Z863 R-DME-2022870 CS-GAG biosynthesis XP_046667254.1 A1Z863 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046686916.1 Q8MUJ1 R-DME-450520 HuR (ELAVL1) binds and stabilizes mRNA XP_046686916.1 Q8MUJ1 R-DME-450531 Regulation of mRNA stability by proteins that bind AU-rich elements XP_046686916.1 Q8MUJ1 R-DME-8953854 Metabolism of RNA XP_046673392.1 P52034 R-DME-1430728 Metabolism XP_046673392.1 P52034 R-DME-168249 Innate Immune System XP_046673392.1 P52034 R-DME-168256 Immune System XP_046673392.1 P52034 R-DME-6798695 Neutrophil degranulation XP_046673392.1 P52034 R-DME-70171 Glycolysis XP_046673392.1 P52034 R-DME-70326 Glucose metabolism XP_046673392.1 P52034 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046664228.1 Q0E9E2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046664228.1 Q0E9E2 R-DME-1430728 Metabolism XP_046664228.1 Q0E9E2 R-DME-196780 Biotin transport and metabolism XP_046664228.1 Q0E9E2 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046664228.1 Q0E9E2 R-DME-196854 Metabolism of vitamins and cofactors XP_046664228.1 Q0E9E2 R-DME-70263 Gluconeogenesis XP_046664228.1 Q0E9E2 R-DME-70268 Pyruvate metabolism XP_046664228.1 Q0E9E2 R-DME-70326 Glucose metabolism XP_046664228.1 Q0E9E2 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046680068.1 Q8MPP3 R-DME-1266738 Developmental Biology XP_046680068.1 Q8MPP3 R-DME-1442490 Collagen degradation XP_046680068.1 Q8MPP3 R-DME-1474228 Degradation of the extracellular matrix XP_046680068.1 Q8MPP3 R-DME-1474244 Extracellular matrix organization XP_046680068.1 Q8MPP3 R-DME-1474290 Collagen formation XP_046680068.1 Q8MPP3 R-DME-1592389 Activation of Matrix Metalloproteinases XP_046680068.1 Q8MPP3 R-DME-162582 Signal Transduction XP_046680068.1 Q8MPP3 R-DME-168249 Innate Immune System XP_046680068.1 Q8MPP3 R-DME-168256 Immune System XP_046680068.1 Q8MPP3 R-DME-2022090 Assembly of collagen fibrils and other multimeric structures XP_046680068.1 Q8MPP3 R-DME-2179392 EGFR Transactivation by Gastrin XP_046680068.1 Q8MPP3 R-DME-2682334 EPH-Ephrin signaling XP_046680068.1 Q8MPP3 R-DME-372790 Signaling by GPCR XP_046680068.1 Q8MPP3 R-DME-388396 GPCR downstream signalling XP_046680068.1 Q8MPP3 R-DME-3928665 EPH-ephrin mediated repulsion of cells XP_046680068.1 Q8MPP3 R-DME-416476 G alpha (q) signalling events XP_046680068.1 Q8MPP3 R-DME-422475 Axon guidance XP_046680068.1 Q8MPP3 R-DME-6798695 Neutrophil degranulation XP_046680068.1 Q8MPP3 R-DME-881907 Gastrin-CREB signalling pathway via PKC and MAPK XP_046680068.1 Q8MPP3 R-DME-9675108 Nervous system development XP_046682170.1 P91622 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682170.1 P91622 R-DME-1430728 Metabolism XP_046682170.1 P91622 R-DME-162582 Signal Transduction XP_046682170.1 P91622 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046682170.1 P91622 R-DME-392499 Metabolism of proteins XP_046682170.1 P91622 R-DME-5362517 Signaling by Retinoic Acid XP_046682170.1 P91622 R-DME-70268 Pyruvate metabolism XP_046682170.1 P91622 R-DME-9006931 Signaling by Nuclear Receptors XP_046682170.1 P91622 R-DME-9837999 Mitochondrial protein degradation XP_046682170.1 P91622 R-DME-9861718 Regulation of pyruvate metabolism XP_046661333.1 P28465 R-DME-162582 Signal Transduction XP_046661333.1 P28465 R-DME-195721 Signaling by WNT XP_046661333.1 P28465 R-DME-3238698 WNT ligand biogenesis and trafficking XP_046673012.1 Q9V595 R-DME-1430728 Metabolism XP_046673012.1 Q9V595 R-DME-189445 Metabolism of porphyrins XP_046673012.1 Q9V595 R-DME-189451 Heme biosynthesis XP_046673459.1 Q7K4A1 R-DME-382551 Transport of small molecules XP_046673459.1 Q7K4A1 R-DME-425397 Transport of vitamins, nucleosides, and related molecules XP_046673459.1 Q7K4A1 R-DME-425407 SLC-mediated transmembrane transport XP_046673459.1 Q7K4A1 R-DME-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane XP_046673459.1 Q7K4A1 R-DME-9748784 Drug ADME XP_046673459.1 Q7K4A1 R-DME-9748787 Azathioprine ADME XP_046673459.1 Q7K4A1 R-DME-9755088 Ribavirin ADME XP_046662199.1 Q7KNF5 R-DME-209405 JAK/STAT pathway XP_046662199.1 Q7KNF5 R-DME-210671 Transcriptional repression by nuclear factors XP_046662199.1 Q7KNF5 R-DME-5252538 Drosophila signaling pathways XP_046662199.1 A1Z7P5 R-DME-1430728 Metabolism XP_046662199.1 A1Z7P5 R-DME-196791 Vitamin D (calciferol) metabolism XP_046662199.1 A1Z7P5 R-DME-2990846 SUMOylation XP_046662199.1 A1Z7P5 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046662199.1 A1Z7P5 R-DME-3232118 SUMOylation of transcription factors XP_046662199.1 A1Z7P5 R-DME-3899300 SUMOylation of transcription cofactors XP_046662199.1 A1Z7P5 R-DME-392499 Metabolism of proteins XP_046662199.1 A1Z7P5 R-DME-4090294 SUMOylation of intracellular receptors XP_046662199.1 A1Z7P5 R-DME-4551638 SUMOylation of chromatin organization proteins XP_046662199.1 A1Z7P5 R-DME-4615885 SUMOylation of DNA replication proteins XP_046662199.1 A1Z7P5 R-DME-4755510 SUMOylation of immune response proteins XP_046662199.1 A1Z7P5 R-DME-556833 Metabolism of lipids XP_046662199.1 A1Z7P5 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046662199.1 A1Z7P5 R-DME-5696398 Nucleotide Excision Repair XP_046662199.1 A1Z7P5 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046662199.1 A1Z7P5 R-DME-597592 Post-translational protein modification XP_046662199.1 A1Z7P5 R-DME-73894 DNA Repair XP_046662199.1 A1Z7P5 R-DME-8957322 Metabolism of steroids XP_046678641.1 Q7K105 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046678641.1 Q7K105 R-DME-168249 Innate Immune System XP_046678641.1 Q7K105 R-DME-168256 Immune System XP_046678641.1 Q7K105 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046678641.1 Q7K105 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046678641.1 Q7K105 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046678641.1 Q7K105 R-DME-209442 Formation of the trans-membrane 'signalling complex' XP_046678641.1 Q7K105 R-DME-209449 Toll pathway XP_046678641.1 Q7K105 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046678641.1 Q7K105 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046678641.1 Q7K105 R-DME-214862 Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' XP_046678641.1 Q7K105 R-DME-214863 Adaptor protein complex binds to TL receptor at the plasma membrane XP_046678641.1 Q7K105 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046678641.1 Q7K105 R-DME-214874 PLL kinase binds to TUB in the TL receptor 'signalling complex' XP_046678641.1 Q7K105 R-DME-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production XP_046678641.1 Q7K105 R-DME-5252538 Drosophila signaling pathways XP_046663675.1 A1Z7R6 R-DME-1430728 Metabolism XP_046663675.1 A1Z7R6 R-DME-196757 Metabolism of folate and pterines XP_046663675.1 A1Z7R6 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046663675.1 A1Z7R6 R-DME-196854 Metabolism of vitamins and cofactors XP_046663675.1 A1Z7R6 R-DME-2262752 Cellular responses to stress XP_046663675.1 A1Z7R6 R-DME-382551 Transport of small molecules XP_046663675.1 A1Z7R6 R-DME-8953897 Cellular responses to stimuli XP_046663675.1 A1Z7R6 R-DME-917937 Iron uptake and transport XP_046663675.1 A1Z7R6 R-DME-9707616 Heme signaling XP_046682642.1 A0A0B4KEG0 R-DME-1430728 Metabolism XP_046682642.1 A0A0B4KEG0 R-DME-196807 Nicotinate metabolism XP_046682642.1 A0A0B4KEG0 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046682642.1 A0A0B4KEG0 R-DME-196854 Metabolism of vitamins and cofactors XP_046682642.1 A0A0B4KEG0 R-DME-392499 Metabolism of proteins XP_046682642.1 A0A0B4KEG0 R-DME-9837999 Mitochondrial protein degradation XP_046677406.1 P52029 R-DME-1430728 Metabolism XP_046677406.1 P52029 R-DME-168249 Innate Immune System XP_046677406.1 P52029 R-DME-168256 Immune System XP_046677406.1 P52029 R-DME-212436 Generic Transcription Pathway XP_046677406.1 P52029 R-DME-3700989 Transcriptional Regulation by TP53 XP_046677406.1 P52029 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046677406.1 P52029 R-DME-6798695 Neutrophil degranulation XP_046677406.1 P52029 R-DME-70171 Glycolysis XP_046677406.1 P52029 R-DME-70263 Gluconeogenesis XP_046677406.1 P52029 R-DME-70326 Glucose metabolism XP_046677406.1 P52029 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046677406.1 P52029 R-DME-73857 RNA Polymerase II Transcription XP_046677406.1 P52029 R-DME-74160 Gene expression (Transcription) XP_046679133.1 C0HK98 R-DME-168249 Innate Immune System XP_046679133.1 C0HK98 R-DME-168256 Immune System XP_046679133.1 C0HK98 R-DME-6798695 Neutrophil degranulation XP_046679133.1 C0HK98 R-DME-6803157 Antimicrobial peptides XP_046679133.1 C0HK99 R-DME-168249 Innate Immune System XP_046679133.1 C0HK99 R-DME-168256 Immune System XP_046679133.1 C0HK99 R-DME-6798695 Neutrophil degranulation XP_046679133.1 C0HK99 R-DME-6803157 Antimicrobial peptides XP_046679133.1 Q9V4X2 R-DME-168249 Innate Immune System XP_046679133.1 Q9V4X2 R-DME-168256 Immune System XP_046679133.1 Q9V4X2 R-DME-6798695 Neutrophil degranulation XP_046679133.1 Q9V4X2 R-DME-6803157 Antimicrobial peptides XP_046668252.1 A1Z7G9 R-DME-1430728 Metabolism XP_046668252.1 A1Z7G9 R-DME-1630316 Glycosaminoglycan metabolism XP_046668252.1 A1Z7G9 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046668252.1 A1Z7G9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046659490.1 Q7JVF1 R-DME-392499 Metabolism of proteins XP_046659490.1 Q7JVF1 R-DME-597592 Post-translational protein modification XP_046659490.1 Q7JVF1 R-DME-8951664 Neddylation XP_046687135.1 Q5BI50 R-DME-110314 Recognition of DNA damage by PCNA-containing replication complex XP_046687135.1 Q5BI50 R-DME-392499 Metabolism of proteins XP_046687135.1 Q5BI50 R-DME-5696394 DNA Damage Recognition in GG-NER XP_046687135.1 Q5BI50 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046687135.1 Q5BI50 R-DME-5696398 Nucleotide Excision Repair XP_046687135.1 Q5BI50 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046687135.1 Q5BI50 R-DME-5696400 Dual Incision in GG-NER XP_046687135.1 Q5BI50 R-DME-597592 Post-translational protein modification XP_046687135.1 Q5BI50 R-DME-6781823 Formation of TC-NER Pre-Incision Complex XP_046687135.1 Q5BI50 R-DME-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) XP_046687135.1 Q5BI50 R-DME-6782135 Dual incision in TC-NER XP_046687135.1 Q5BI50 R-DME-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER XP_046687135.1 Q5BI50 R-DME-73893 DNA Damage Bypass XP_046687135.1 Q5BI50 R-DME-73894 DNA Repair XP_046687135.1 Q5BI50 R-DME-8951664 Neddylation XP_046671909.1 Q24311 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046671909.1 Q24311 R-DME-1169091 Activation of NF-kappaB in B cells XP_046671909.1 Q24311 R-DME-1280215 Cytokine Signaling in Immune system XP_046671909.1 Q24311 R-DME-1280218 Adaptive Immune System XP_046671909.1 Q24311 R-DME-162582 Signal Transduction XP_046671909.1 Q24311 R-DME-1640170 Cell Cycle XP_046671909.1 Q24311 R-DME-168249 Innate Immune System XP_046671909.1 Q24311 R-DME-168256 Immune System XP_046671909.1 Q24311 R-DME-174113 SCF-beta-TrCP mediated degradation of Emi1 XP_046671909.1 Q24311 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046671909.1 Q24311 R-DME-176408 Regulation of APC/C activators between G1/S and early anaphase XP_046671909.1 Q24311 R-DME-187577 SCF(Skp2)-mediated degradation of p27/p21 XP_046671909.1 Q24311 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046671909.1 Q24311 R-DME-195721 Signaling by WNT XP_046671909.1 Q24311 R-DME-202403 TCR signaling XP_046671909.1 Q24311 R-DME-202424 Downstream TCR signaling XP_046671909.1 Q24311 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046671909.1 Q24311 R-DME-209392 Hedgehog pathway XP_046671909.1 Q24311 R-DME-209412 Wingless pathway XP_046671909.1 Q24311 R-DME-209441 WG ligand not bound to FZ receptors XP_046671909.1 Q24311 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046671909.1 Q24311 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046671909.1 Q24311 R-DME-212436 Generic Transcription Pathway XP_046671909.1 Q24311 R-DME-2262752 Cellular responses to stress XP_046671909.1 Q24311 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046671909.1 Q24311 R-DME-2565942 Regulation of PLK1 Activity at G2/M Transition XP_046671909.1 Q24311 R-DME-2871837 FCERI mediated NF-kB activation XP_046671909.1 Q24311 R-DME-382551 Transport of small molecules XP_046671909.1 Q24311 R-DME-392499 Metabolism of proteins XP_046671909.1 Q24311 R-DME-446652 Interleukin-1 family signaling XP_046671909.1 Q24311 R-DME-449147 Signaling by Interleukins XP_046671909.1 Q24311 R-DME-453274 Mitotic G2-G2/M phases XP_046671909.1 Q24311 R-DME-453276 Regulation of mitotic cell cycle XP_046671909.1 Q24311 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046671909.1 Q24311 R-DME-5252538 Drosophila signaling pathways XP_046671909.1 Q24311 R-DME-5358351 Signaling by Hedgehog XP_046671909.1 Q24311 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046671909.1 Q24311 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046671909.1 Q24311 R-DME-5610780 Degradation of GLI1 by the proteasome XP_046671909.1 Q24311 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046671909.1 Q24311 R-DME-5610787 Hedgehog 'off' state XP_046671909.1 Q24311 R-DME-5621481 C-type lectin receptors (CLRs) XP_046671909.1 Q24311 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046671909.1 Q24311 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046671909.1 Q24311 R-DME-597592 Post-translational protein modification XP_046671909.1 Q24311 R-DME-68949 Orc1 removal from chromatin XP_046671909.1 Q24311 R-DME-69052 Switching of origins to a post-replicative state XP_046671909.1 Q24311 R-DME-69202 Cyclin E associated events during G1/S transition XP_046671909.1 Q24311 R-DME-69206 G1/S Transition XP_046671909.1 Q24311 R-DME-69231 Cyclin D associated events in G1 XP_046671909.1 Q24311 R-DME-69236 G1 Phase XP_046671909.1 Q24311 R-DME-69239 Synthesis of DNA XP_046671909.1 Q24311 R-DME-69242 S Phase XP_046671909.1 Q24311 R-DME-69275 G2/M Transition XP_046671909.1 Q24311 R-DME-69278 Cell Cycle, Mitotic XP_046671909.1 Q24311 R-DME-69306 DNA Replication XP_046671909.1 Q24311 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046671909.1 Q24311 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046671909.1 Q24311 R-DME-69615 G1/S DNA Damage Checkpoints XP_046671909.1 Q24311 R-DME-69620 Cell Cycle Checkpoints XP_046671909.1 Q24311 R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry XP_046671909.1 Q24311 R-DME-73857 RNA Polymerase II Transcription XP_046671909.1 Q24311 R-DME-74160 Gene expression (Transcription) XP_046671909.1 Q24311 R-DME-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis XP_046671909.1 Q24311 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046671909.1 Q24311 R-DME-8939902 Regulation of RUNX2 expression and activity XP_046671909.1 Q24311 R-DME-8951664 Neddylation XP_046671909.1 Q24311 R-DME-8953897 Cellular responses to stimuli XP_046671909.1 Q24311 R-DME-9020702 Interleukin-1 signaling XP_046671909.1 Q24311 R-DME-917937 Iron uptake and transport XP_046671909.1 Q24311 R-DME-9711123 Cellular response to chemical stress XP_046671909.1 Q24311 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046671909.1 Q24311 R-DME-9759194 Nuclear events mediated by NFE2L2 XP_046671909.1 Q24311 R-DME-9762114 GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 XP_046671909.1 Q24311 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046671909.1 Q24311 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046671909.1 Q24311 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046659487.1 Q8MKN0 R-DME-1430728 Metabolism XP_046659487.1 Q8MKN0 R-DME-196854 Metabolism of vitamins and cofactors XP_046659487.1 Q8MKN0 R-DME-2142789 Ubiquinol biosynthesis XP_046659487.1 Q8MKN0 R-DME-8978934 Metabolism of cofactors XP_046682387.1 Q95RV5 R-DME-1430728 Metabolism XP_046682387.1 Q95RV5 R-DME-71336 Pentose phosphate pathway XP_046682387.1 Q95RV5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046681996.1 O16844 R-DME-209159 Assembly of the CI containing complexes XP_046681996.1 O16844 R-DME-209190 Phosphorylation of CI XP_046681996.1 O16844 R-DME-209214 Phosphorylation of SMO XP_046681996.1 O16844 R-DME-209338 Assembly of the 'signalling complexes' XP_046681996.1 O16844 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046681996.1 O16844 R-DME-209392 Hedgehog pathway XP_046681996.1 O16844 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046681996.1 O16844 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046681996.1 O16844 R-DME-216119 Activation of CI XP_046681996.1 O16844 R-DME-216217 Activation of SMO XP_046681996.1 O16844 R-DME-5252538 Drosophila signaling pathways XP_046667303.1 Q7JWX3 R-DME-109582 Hemostasis XP_046667303.1 Q7JWX3 R-DME-114608 Platelet degranulation XP_046667303.1 Q7JWX3 R-DME-1474244 Extracellular matrix organization XP_046667303.1 Q7JWX3 R-DME-1474290 Collagen formation XP_046667303.1 Q7JWX3 R-DME-1650814 Collagen biosynthesis and modifying enzymes XP_046667303.1 Q7JWX3 R-DME-168249 Innate Immune System XP_046667303.1 Q7JWX3 R-DME-168256 Immune System XP_046667303.1 Q7JWX3 R-DME-212436 Generic Transcription Pathway XP_046667303.1 Q7JWX3 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046667303.1 Q7JWX3 R-DME-392499 Metabolism of proteins XP_046667303.1 Q7JWX3 R-DME-597592 Post-translational protein modification XP_046667303.1 Q7JWX3 R-DME-6798695 Neutrophil degranulation XP_046667303.1 Q7JWX3 R-DME-73857 RNA Polymerase II Transcription XP_046667303.1 Q7JWX3 R-DME-74160 Gene expression (Transcription) XP_046667303.1 Q7JWX3 R-DME-76002 Platelet activation, signaling and aggregation XP_046667303.1 Q7JWX3 R-DME-76005 Response to elevated platelet cytosolic Ca2+ XP_046667303.1 Q7JWX3 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046667303.1 Q7JWX3 R-DME-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes XP_046667303.1 Q7JWX3 R-DME-8957275 Post-translational protein phosphorylation XP_046667303.1 Q7JWX3 R-DME-9686114 Non-canonical inflammasome activation XP_046667303.1 Q7JWX3 R-DME-9855719 Regulation of FXIIa and plasma kallikrein activity XP_046667303.1 Q7JWX3 R-DME-9948001 CASP4 inflammasome assembly XP_046667303.1 Q7JWX3 R-DME-9970672 FXIIa activates plasma kallikrein-kinin system XP_046674452.1 Q9Y117 R-DME-392499 Metabolism of proteins XP_046674452.1 Q9Y117 R-DME-5173105 O-linked glycosylation XP_046674452.1 Q9Y117 R-DME-597592 Post-translational protein modification XP_046674452.1 Q9Y117 R-DME-913709 O-linked glycosylation of mucins XP_046674109.1 Q9V4E0 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046674109.1 Q9V4E0 R-DME-1430728 Metabolism XP_046674109.1 Q9V4E0 R-DME-611105 Respiratory electron transport XP_046674109.1 Q9V4E0 R-DME-6799198 Complex I biogenesis XP_046682707.1 Q961D9 R-DME-162582 Signal Transduction XP_046682707.1 Q961D9 R-DME-195721 Signaling by WNT XP_046682707.1 Q961D9 R-DME-201681 TCF dependent signaling in response to WNT XP_046682707.1 Q961D9 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046682707.1 Q961D9 R-DME-209407 Transport of ARM to the nucleus XP_046682707.1 Q961D9 R-DME-209412 Wingless pathway XP_046682707.1 Q961D9 R-DME-209421 Transcription activation by ARM XP_046682707.1 Q961D9 R-DME-209469 WG ligand bound to FZ receptors XP_046682707.1 Q961D9 R-DME-5252538 Drosophila signaling pathways XP_046683153.1 Q9XYM0 R-DME-1280215 Cytokine Signaling in Immune system XP_046683153.1 Q9XYM0 R-DME-162582 Signal Transduction XP_046683153.1 Q9XYM0 R-DME-168256 Immune System XP_046683153.1 Q9XYM0 R-DME-186763 Downstream signal transduction XP_046683153.1 Q9XYM0 R-DME-186797 Signaling by PDGF XP_046683153.1 Q9XYM0 R-DME-449147 Signaling by Interleukins XP_046683153.1 Q9XYM0 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046683153.1 Q9XYM0 R-DME-8848021 Signaling by PTK6 XP_046683153.1 Q9XYM0 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046683153.1 Q9XYM0 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046683153.1 Q9XYM0 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046683153.1 Q9XYM0 R-DME-912631 Regulation of signaling by CBL XP_046682489.1 P19538 R-DME-162582 Signal Transduction XP_046682489.1 P19538 R-DME-209159 Assembly of the CI containing complexes XP_046682489.1 P19538 R-DME-209190 Phosphorylation of CI XP_046682489.1 P19538 R-DME-209214 Phosphorylation of SMO XP_046682489.1 P19538 R-DME-209338 Assembly of the 'signalling complexes' XP_046682489.1 P19538 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046682489.1 P19538 R-DME-209392 Hedgehog pathway XP_046682489.1 P19538 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046682489.1 P19538 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046682489.1 P19538 R-DME-216119 Activation of CI XP_046682489.1 P19538 R-DME-216167 Nuclear CI is degraded XP_046682489.1 P19538 R-DME-216217 Activation of SMO XP_046682489.1 P19538 R-DME-5252538 Drosophila signaling pathways XP_046682489.1 P19538 R-DME-5358351 Signaling by Hedgehog XP_046682489.1 P19538 R-DME-5610780 Degradation of GLI1 by the proteasome XP_046682489.1 P19538 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046682489.1 P19538 R-DME-5610787 Hedgehog 'off' state XP_046682489.1 P19538 R-DME-5632684 Hedgehog 'on' state XP_046672890.1 Q05825 R-DME-1268020 Mitochondrial protein import XP_046672890.1 Q05825 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046672890.1 Q05825 R-DME-1430728 Metabolism XP_046672890.1 Q05825 R-DME-1592230 Mitochondrial biogenesis XP_046672890.1 Q05825 R-DME-163210 Formation of ATP by chemiosmotic coupling XP_046672890.1 Q05825 R-DME-1852241 Organelle biogenesis and maintenance XP_046672890.1 Q05825 R-DME-392499 Metabolism of proteins XP_046672890.1 Q05825 R-DME-8949613 Cristae formation XP_046672890.1 Q05825 R-DME-9609507 Protein localization XP_046672890.1 Q05825 R-DME-9837999 Mitochondrial protein degradation XP_046672110.1 O61643 R-DME-1502540 Signaling by Activin XP_046672110.1 O61643 R-DME-162582 Signal Transduction XP_046672110.1 O61643 R-DME-9006936 Signaling by TGFB family members XP_046672357.1 Q9N675 R-DME-1500931 Cell-Cell communication XP_046672357.1 Q9N675 R-DME-446353 Cell-extracellular matrix interactions XP_046672357.1 Q9N675 R-DME-446728 Cell junction organization XP_046667151.1 Q94527 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046667151.1 Q94527 R-DME-1169091 Activation of NF-kappaB in B cells XP_046667151.1 Q94527 R-DME-1280215 Cytokine Signaling in Immune system XP_046667151.1 Q94527 R-DME-1280218 Adaptive Immune System XP_046667151.1 Q94527 R-DME-1500931 Cell-Cell communication XP_046667151.1 Q94527 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046667151.1 Q94527 R-DME-162582 Signal Transduction XP_046667151.1 Q94527 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046667151.1 Q94527 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046667151.1 Q94527 R-DME-166166 MyD88-independent TLR4 cascade XP_046667151.1 Q94527 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046667151.1 Q94527 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046667151.1 Q94527 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046667151.1 Q94527 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046667151.1 Q94527 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046667151.1 Q94527 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046667151.1 Q94527 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046667151.1 Q94527 R-DME-168249 Innate Immune System XP_046667151.1 Q94527 R-DME-168256 Immune System XP_046667151.1 Q94527 R-DME-168898 Toll-like Receptor Cascades XP_046667151.1 Q94527 R-DME-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta XP_046667151.1 Q94527 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046667151.1 Q94527 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046667151.1 Q94527 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046667151.1 Q94527 R-DME-193639 p75NTR signals via NF-kB XP_046667151.1 Q94527 R-DME-193704 p75 NTR receptor-mediated signalling XP_046667151.1 Q94527 R-DME-202403 TCR signaling XP_046667151.1 Q94527 R-DME-202424 Downstream TCR signaling XP_046667151.1 Q94527 R-DME-209394 Transcriptional activtion and repression of REL-68 target genes XP_046667151.1 Q94527 R-DME-209438 Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046667151.1 Q94527 R-DME-209459 Imd pathway XP_046667151.1 Q94527 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046667151.1 Q94527 R-DME-209560 NF-kB is activated and signals survival XP_046667151.1 Q94527 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046667151.1 Q94527 R-DME-214411 REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046667151.1 Q94527 R-DME-214416 Phosphorylated REL is cleaved by and dissociates from DREDD XP_046667151.1 Q94527 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046667151.1 Q94527 R-DME-2871837 FCERI mediated NF-kB activation XP_046667151.1 Q94527 R-DME-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production XP_046667151.1 Q94527 R-DME-418990 Adherens junctions interactions XP_046667151.1 Q94527 R-DME-421270 Cell-cell junction organization XP_046667151.1 Q94527 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046667151.1 Q94527 R-DME-446652 Interleukin-1 family signaling XP_046667151.1 Q94527 R-DME-446728 Cell junction organization XP_046667151.1 Q94527 R-DME-449147 Signaling by Interleukins XP_046667151.1 Q94527 R-DME-5252538 Drosophila signaling pathways XP_046667151.1 Q94527 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046667151.1 Q94527 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046667151.1 Q94527 R-DME-5621481 C-type lectin receptors (CLRs) XP_046667151.1 Q94527 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046667151.1 Q94527 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046667151.1 Q94527 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046667151.1 Q94527 R-DME-6798695 Neutrophil degranulation XP_046667151.1 Q94527 R-DME-73887 Death Receptor Signaling XP_046667151.1 Q94527 R-DME-8953897 Cellular responses to stimuli XP_046667151.1 Q94527 R-DME-9020702 Interleukin-1 signaling XP_046667151.1 Q94527 R-DME-933542 TRAF6 mediated NF-kB activation XP_046667151.1 Q94527 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046667151.1 Q94527 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046667151.1 Q94527 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046667151.1 Q94527 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046667151.1 Q94527 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046667151.1 Q94527 R-DME-9855142 Cellular responses to mechanical stimuli XP_046667151.1 Q94527 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046667151.1 Q94527 R-DME-9860931 Response of endothelial cells to shear stress XP_046667151.1 Q94527 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046661166.1 P18502 R-DME-162582 Signal Transduction XP_046661166.1 P18502 R-DME-209338 Assembly of the 'signalling complexes' XP_046661166.1 P18502 R-DME-209392 Hedgehog pathway XP_046661166.1 P18502 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046661166.1 P18502 R-DME-5252538 Drosophila signaling pathways XP_046661166.1 P18502 R-DME-5358351 Signaling by Hedgehog XP_046661166.1 P18502 R-DME-5610787 Hedgehog 'off' state XP_046661166.1 P18502 R-DME-5632681 Ligand-receptor interactions XP_046661166.1 P18502 R-DME-5632684 Hedgehog 'on' state XP_046659041.1 P51023 R-DME-2262752 Cellular responses to stress XP_046659041.1 P51023 R-DME-2559583 Cellular Senescence XP_046659041.1 P51023 R-DME-2559585 Oncogene Induced Senescence XP_046659041.1 P51023 R-DME-8953897 Cellular responses to stimuli XP_046660667.1 Q960X8 R-DME-162582 Signal Transduction XP_046660667.1 Q960X8 R-DME-177929 Signaling by EGFR XP_046660667.1 Q960X8 R-DME-182971 EGFR downregulation XP_046660667.1 Q960X8 R-DME-194315 Signaling by Rho GTPases XP_046660667.1 Q960X8 R-DME-199991 Membrane Trafficking XP_046660667.1 Q960X8 R-DME-199992 trans-Golgi Network Vesicle Budding XP_046660667.1 Q960X8 R-DME-392499 Metabolism of proteins XP_046660667.1 Q960X8 R-DME-432720 Lysosome Vesicle Biogenesis XP_046660667.1 Q960X8 R-DME-5653656 Vesicle-mediated transport XP_046660667.1 Q960X8 R-DME-5688426 Deubiquitination XP_046660667.1 Q960X8 R-DME-5689880 Ub-specific processing proteases XP_046660667.1 Q960X8 R-DME-597592 Post-translational protein modification XP_046660667.1 Q960X8 R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis XP_046660667.1 Q960X8 R-DME-8856828 Clathrin-mediated endocytosis XP_046660667.1 Q960X8 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660667.1 Q960X8 R-DME-9012999 RHO GTPase cycle XP_046660667.1 Q960X8 R-DME-9013420 RHOU GTPase cycle XP_046660667.1 Q960X8 R-DME-917729 Endosomal Sorting Complex Required For Transport (ESCRT) XP_046660667.1 Q960X8 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046673327.1 Q7KU08 R-DME-157118 Signaling by NOTCH XP_046673327.1 Q7KU08 R-DME-162582 Signal Transduction XP_046673327.1 Q7KU08 R-DME-1980145 Signaling by NOTCH2 XP_046673327.1 Q7KU08 R-DME-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus XP_046672838.1 Q7KMQ6 R-DME-110478 Insulin signaling pathway XP_046672838.1 Q7KMQ6 R-DME-110526 Insulin receptor mediated signaling XP_046672838.1 Q7KMQ6 R-DME-1257604 PIP3 activates AKT signaling XP_046672838.1 Q7KMQ6 R-DME-1280218 Adaptive Immune System XP_046672838.1 Q7KMQ6 R-DME-1430728 Metabolism XP_046672838.1 Q7KMQ6 R-DME-1483249 Inositol phosphate metabolism XP_046672838.1 Q7KMQ6 R-DME-1483255 PI Metabolism XP_046672838.1 Q7KMQ6 R-DME-1483257 Phospholipid metabolism XP_046672838.1 Q7KMQ6 R-DME-162582 Signal Transduction XP_046672838.1 Q7KMQ6 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046672838.1 Q7KMQ6 R-DME-168256 Immune System XP_046672838.1 Q7KMQ6 R-DME-1855204 Synthesis of IP3 and IP4 in the cytosol XP_046672838.1 Q7KMQ6 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046672838.1 Q7KMQ6 R-DME-202403 TCR signaling XP_046672838.1 Q7KMQ6 R-DME-202424 Downstream TCR signaling XP_046672838.1 Q7KMQ6 R-DME-392499 Metabolism of proteins XP_046672838.1 Q7KMQ6 R-DME-5252538 Drosophila signaling pathways XP_046672838.1 Q7KMQ6 R-DME-556833 Metabolism of lipids XP_046672838.1 Q7KMQ6 R-DME-5688426 Deubiquitination XP_046672838.1 Q7KMQ6 R-DME-5689880 Ub-specific processing proteases XP_046672838.1 Q7KMQ6 R-DME-597592 Post-translational protein modification XP_046672838.1 Q7KMQ6 R-DME-6807070 PTEN Regulation XP_046672838.1 Q7KMQ6 R-DME-8948747 Regulation of PTEN localization XP_046672838.1 Q7KMQ6 R-DME-8948751 Regulation of PTEN stability and activity XP_046672838.1 Q7KMQ6 R-DME-9006925 Intracellular signaling by second messengers XP_046679873.1 P18824 R-DME-109581 Apoptosis XP_046679873.1 P18824 R-DME-111465 Apoptotic cleavage of cellular proteins XP_046679873.1 P18824 R-DME-1266738 Developmental Biology XP_046679873.1 P18824 R-DME-1500931 Cell-Cell communication XP_046679873.1 P18824 R-DME-162582 Signal Transduction XP_046679873.1 P18824 R-DME-168249 Innate Immune System XP_046679873.1 P18824 R-DME-168256 Immune System XP_046679873.1 P18824 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046679873.1 P18824 R-DME-194138 Signaling by VEGF XP_046679873.1 P18824 R-DME-194315 Signaling by Rho GTPases XP_046679873.1 P18824 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046679873.1 P18824 R-DME-195721 Signaling by WNT XP_046679873.1 P18824 R-DME-196299 Beta-catenin phosphorylation cascade XP_046679873.1 P18824 R-DME-201681 TCF dependent signaling in response to WNT XP_046679873.1 P18824 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046679873.1 P18824 R-DME-209214 Phosphorylation of SMO XP_046679873.1 P18824 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046679873.1 P18824 R-DME-209392 Hedgehog pathway XP_046679873.1 P18824 R-DME-209396 Phosphorylation of ARM XP_046679873.1 P18824 R-DME-209407 Transport of ARM to the nucleus XP_046679873.1 P18824 R-DME-209412 Wingless pathway XP_046679873.1 P18824 R-DME-209413 Assembly of the 'destruction complex' XP_046679873.1 P18824 R-DME-209421 Transcription activation by ARM XP_046679873.1 P18824 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046679873.1 P18824 R-DME-209441 WG ligand not bound to FZ receptors XP_046679873.1 P18824 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046679873.1 P18824 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046679873.1 P18824 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046679873.1 P18824 R-DME-209469 WG ligand bound to FZ receptors XP_046679873.1 P18824 R-DME-212436 Generic Transcription Pathway XP_046679873.1 P18824 R-DME-216217 Activation of SMO XP_046679873.1 P18824 R-DME-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production XP_046679873.1 P18824 R-DME-351906 Apoptotic cleavage of cell adhesion proteins XP_046679873.1 P18824 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046679873.1 P18824 R-DME-3858494 Beta-catenin independent WNT signaling XP_046679873.1 P18824 R-DME-4086398 Ca2+ pathway XP_046679873.1 P18824 R-DME-418990 Adherens junctions interactions XP_046679873.1 P18824 R-DME-421270 Cell-cell junction organization XP_046679873.1 P18824 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046679873.1 P18824 R-DME-446728 Cell junction organization XP_046679873.1 P18824 R-DME-4839726 Chromatin organization XP_046679873.1 P18824 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046679873.1 P18824 R-DME-5252538 Drosophila signaling pathways XP_046679873.1 P18824 R-DME-525793 Myogenesis XP_046679873.1 P18824 R-DME-5357801 Programmed Cell Death XP_046679873.1 P18824 R-DME-6798695 Neutrophil degranulation XP_046679873.1 P18824 R-DME-6805567 Keratinization XP_046679873.1 P18824 R-DME-6809371 Formation of the cornified envelope XP_046679873.1 P18824 R-DME-73857 RNA Polymerase II Transcription XP_046679873.1 P18824 R-DME-74160 Gene expression (Transcription) XP_046679873.1 P18824 R-DME-75153 Apoptotic execution phase XP_046679873.1 P18824 R-DME-8853884 Transcriptional Regulation by VENTX XP_046679873.1 P18824 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046679873.1 P18824 R-DME-8951430 RUNX3 regulates WNT signaling XP_046679873.1 P18824 R-DME-8980692 RHOA GTPase cycle XP_046679873.1 P18824 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046679873.1 P18824 R-DME-9012999 RHO GTPase cycle XP_046679873.1 P18824 R-DME-9013406 RHOQ GTPase cycle XP_046679873.1 P18824 R-DME-9013407 RHOH GTPase cycle XP_046679873.1 P18824 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046679873.1 P18824 R-DME-9730414 MITF-M-regulated melanocyte development XP_046679873.1 P18824 R-DME-9759476 Regulation of Homotypic Cell-Cell Adhesion XP_046679873.1 P18824 R-DME-9764265 Regulation of CDH1 Expression and Function XP_046679873.1 P18824 R-DME-9764274 Regulation of Expression and Function of Type I Classical Cadherins XP_046679873.1 P18824 R-DME-9764561 Regulation of CDH1 Function XP_046679873.1 P18824 R-DME-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation XP_046679873.1 P18824 R-DME-9856651 MITF-M-dependent gene expression XP_046679873.1 P18824 R-DME-9932444 ATP-dependent chromatin remodelers XP_046679873.1 P18824 R-DME-9937848 CHD chromatin remodelers XP_046679873.1 P18824 R-DME-9943962 CHD6, CHD7, CHD8, CHD9 subfamily XP_046679873.1 P18824 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046667070.1 A0A0B4K7Q6 R-DME-109582 Hemostasis XP_046667070.1 A0A0B4K7Q6 R-DME-1500931 Cell-Cell communication XP_046667070.1 A0A0B4K7Q6 R-DME-162582 Signal Transduction XP_046667070.1 A0A0B4K7Q6 R-DME-168249 Innate Immune System XP_046667070.1 A0A0B4K7Q6 R-DME-168256 Immune System XP_046667070.1 A0A0B4K7Q6 R-DME-194315 Signaling by Rho GTPases XP_046667070.1 A0A0B4K7Q6 R-DME-418990 Adherens junctions interactions XP_046667070.1 A0A0B4K7Q6 R-DME-421270 Cell-cell junction organization XP_046667070.1 A0A0B4K7Q6 R-DME-446728 Cell junction organization XP_046667070.1 A0A0B4K7Q6 R-DME-6798695 Neutrophil degranulation XP_046667070.1 A0A0B4K7Q6 R-DME-8848021 Signaling by PTK6 XP_046667070.1 A0A0B4K7Q6 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046667070.1 A0A0B4K7Q6 R-DME-8980692 RHOA GTPase cycle XP_046667070.1 A0A0B4K7Q6 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046667070.1 A0A0B4K7Q6 R-DME-9012999 RHO GTPase cycle XP_046667070.1 A0A0B4K7Q6 R-DME-9013149 RAC1 GTPase cycle XP_046667070.1 A0A0B4K7Q6 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046667070.1 A0A0B4K7Q6 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046667070.1 A0A0B4K7Q6 R-DME-9958810 SRC activates STAT3 in a quantitative manner, through Cadherin-11 (CDH11), RAC1 and gp130 (IL6ST) XP_046667070.1 A0A0B4K7Q6 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046676608.1 Q9VY44 R-DME-72086 mRNA Capping XP_046676608.1 Q9VY44 R-DME-73857 RNA Polymerase II Transcription XP_046676608.1 Q9VY44 R-DME-74160 Gene expression (Transcription) XP_046676608.1 Q9VY44 R-DME-77075 RNA Pol II CTD phosphorylation and interaction with CE XP_046676608.1 Q9VY44 R-DME-8953854 Metabolism of RNA XP_046682424.1 Q8SYJ2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046682424.1 Q8SYJ2 R-DME-1430728 Metabolism XP_046682424.1 Q8SYJ2 R-DME-212436 Generic Transcription Pathway XP_046682424.1 Q8SYJ2 R-DME-2262752 Cellular responses to stress XP_046682424.1 Q8SYJ2 R-DME-3700989 Transcriptional Regulation by TP53 XP_046682424.1 Q8SYJ2 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046682424.1 Q8SYJ2 R-DME-611105 Respiratory electron transport XP_046682424.1 Q8SYJ2 R-DME-73857 RNA Polymerase II Transcription XP_046682424.1 Q8SYJ2 R-DME-74160 Gene expression (Transcription) XP_046682424.1 Q8SYJ2 R-DME-8953897 Cellular responses to stimuli XP_046682424.1 Q8SYJ2 R-DME-9707564 Cytoprotection by HMOX1 XP_046682424.1 Q8SYJ2 R-DME-9711123 Cellular response to chemical stress XP_046682424.1 Q8SYJ2 R-DME-9864848 Complex IV assembly XP_046679984.1 Q95RG8 R-DME-1266738 Developmental Biology XP_046679984.1 Q95RG8 R-DME-162582 Signal Transduction XP_046679984.1 Q95RG8 R-DME-194315 Signaling by Rho GTPases XP_046679984.1 Q95RG8 R-DME-2682334 EPH-Ephrin signaling XP_046679984.1 Q95RG8 R-DME-3928664 Ephrin signaling XP_046679984.1 Q95RG8 R-DME-422475 Axon guidance XP_046679984.1 Q95RG8 R-DME-9012999 RHO GTPase cycle XP_046679984.1 Q95RG8 R-DME-9013149 RAC1 GTPase cycle XP_046679984.1 Q95RG8 R-DME-9013406 RHOQ GTPase cycle XP_046679984.1 Q95RG8 R-DME-9013420 RHOU GTPase cycle XP_046679984.1 Q95RG8 R-DME-9013423 RAC3 GTPase cycle XP_046679984.1 Q95RG8 R-DME-9013424 RHOV GTPase cycle XP_046679984.1 Q95RG8 R-DME-9675108 Nervous system development XP_046679984.1 Q95RG8 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046678393.1 Q8IR23 R-DME-1266738 Developmental Biology XP_046678393.1 Q8IR23 R-DME-162582 Signal Transduction XP_046678393.1 Q8IR23 R-DME-186763 Downstream signal transduction XP_046678393.1 Q8IR23 R-DME-186797 Signaling by PDGF XP_046678393.1 Q8IR23 R-DME-194138 Signaling by VEGF XP_046678393.1 Q8IR23 R-DME-2682334 EPH-Ephrin signaling XP_046678393.1 Q8IR23 R-DME-3928662 EPHB-mediated forward signaling XP_046678393.1 Q8IR23 R-DME-422475 Axon guidance XP_046678393.1 Q8IR23 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046678393.1 Q8IR23 R-DME-5218921 VEGFR2 mediated cell proliferation XP_046678393.1 Q8IR23 R-DME-5658442 Regulation of RAS by GAPs XP_046678393.1 Q8IR23 R-DME-5673001 RAF/MAP kinase cascade XP_046678393.1 Q8IR23 R-DME-5683057 MAPK family signaling cascades XP_046678393.1 Q8IR23 R-DME-5684996 MAPK1/MAPK3 signaling XP_046678393.1 Q8IR23 R-DME-8848021 Signaling by PTK6 XP_046678393.1 Q8IR23 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046678393.1 Q8IR23 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046678393.1 Q8IR23 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046678393.1 Q8IR23 R-DME-9675108 Nervous system development XP_046662425.1 Q9VXK7 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046662425.1 Q9VXK7 R-DME-1430728 Metabolism XP_046662425.1 Q9VXK7 R-DME-611105 Respiratory electron transport XP_046662425.1 Q9VXK7 R-DME-6799198 Complex I biogenesis XP_046676978.1 Q9VMW8 R-DME-392499 Metabolism of proteins XP_046676978.1 Q9VMW8 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046676978.1 Q9VMW8 R-DME-446203 Asparagine N-linked glycosylation XP_046676978.1 Q9VMW8 R-DME-597592 Post-translational protein modification XP_046667113.1 Q9VMW9 R-DME-392499 Metabolism of proteins XP_046667113.1 Q9VMW9 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046667113.1 Q9VMW9 R-DME-446203 Asparagine N-linked glycosylation XP_046667113.1 Q9VMW9 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046667113.1 Q9VMW9 R-DME-597592 Post-translational protein modification XP_046667113.1 Q9VMW9 R-DME-6787639 GDP-fucose biosynthesis XP_046664791.1 Q59E14 R-DME-109582 Hemostasis XP_046664791.1 Q59E14 R-DME-1266738 Developmental Biology XP_046664791.1 Q59E14 R-DME-1430728 Metabolism XP_046664791.1 Q59E14 R-DME-1474228 Degradation of the extracellular matrix XP_046664791.1 Q59E14 R-DME-1474244 Extracellular matrix organization XP_046664791.1 Q59E14 R-DME-162582 Signal Transduction XP_046664791.1 Q59E14 R-DME-1630316 Glycosaminoglycan metabolism XP_046664791.1 Q59E14 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046664791.1 Q59E14 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046664791.1 Q59E14 R-DME-2022928 HS-GAG biosynthesis XP_046664791.1 Q59E14 R-DME-2024096 HS-GAG degradation XP_046664791.1 Q59E14 R-DME-216083 Integrin cell surface interactions XP_046664791.1 Q59E14 R-DME-3000171 Non-integrin membrane-ECM interactions XP_046664791.1 Q59E14 R-DME-3000178 ECM proteoglycans XP_046664791.1 Q59E14 R-DME-373760 L1CAM interactions XP_046664791.1 Q59E14 R-DME-375165 NCAM signaling for neurite out-growth XP_046664791.1 Q59E14 R-DME-419037 NCAM1 interactions XP_046664791.1 Q59E14 R-DME-422475 Axon guidance XP_046664791.1 Q59E14 R-DME-445144 Signal transduction by L1 XP_046664791.1 Q59E14 R-DME-5673001 RAF/MAP kinase cascade XP_046664791.1 Q59E14 R-DME-5683057 MAPK family signaling cascades XP_046664791.1 Q59E14 R-DME-5684996 MAPK1/MAPK3 signaling XP_046664791.1 Q59E14 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046664791.1 Q59E14 R-DME-9675108 Nervous system development XP_046664791.1 Q59E14 R-DME-9769739 Regulation of clotting cascade XP_046664791.1 Q59E14 R-DME-9769740 Coagulation pathway XP_046664791.1 Q59E14 R-DME-9913351 Formation of the dystrophin-glycoprotein complex (DGC) XP_046665104.1 Q95UN8 R-DME-109581 Apoptosis XP_046665104.1 Q95UN8 R-DME-140534 Caspase activation via Death Receptors in the presence of ligand XP_046665104.1 Q95UN8 R-DME-162582 Signal Transduction XP_046665104.1 Q95UN8 R-DME-194315 Signaling by Rho GTPases XP_046665104.1 Q95UN8 R-DME-3371378 Regulation by c-FLIP XP_046665104.1 Q95UN8 R-DME-392499 Metabolism of proteins XP_046665104.1 Q95UN8 R-DME-5213460 RIPK1-mediated regulated necrosis XP_046665104.1 Q95UN8 R-DME-5218859 Regulated Necrosis XP_046665104.1 Q95UN8 R-DME-5218900 CASP8 activity is inhibited XP_046665104.1 Q95UN8 R-DME-5357769 Caspase activation via extrinsic apoptotic signalling pathway XP_046665104.1 Q95UN8 R-DME-5357801 Programmed Cell Death XP_046665104.1 Q95UN8 R-DME-5357905 Regulation of TNFR1 signaling XP_046665104.1 Q95UN8 R-DME-5673000 RAF activation XP_046665104.1 Q95UN8 R-DME-5673001 RAF/MAP kinase cascade XP_046665104.1 Q95UN8 R-DME-5675482 Regulation of necroptotic cell death XP_046665104.1 Q95UN8 R-DME-5683057 MAPK family signaling cascades XP_046665104.1 Q95UN8 R-DME-5684996 MAPK1/MAPK3 signaling XP_046665104.1 Q95UN8 R-DME-5688426 Deubiquitination XP_046665104.1 Q95UN8 R-DME-5689880 Ub-specific processing proteases XP_046665104.1 Q95UN8 R-DME-5689896 Ovarian tumor domain proteases XP_046665104.1 Q95UN8 R-DME-597592 Post-translational protein modification XP_046665104.1 Q95UN8 R-DME-69416 Dimerization of procaspase-8 XP_046665104.1 Q95UN8 R-DME-73887 Death Receptor Signaling XP_046665104.1 Q95UN8 R-DME-75893 TNF signaling XP_046665104.1 Q95UN8 R-DME-9012999 RHO GTPase cycle XP_046665104.1 Q95UN8 R-DME-9013424 RHOV GTPase cycle XP_046665104.1 Q95UN8 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046664456.1 Q94918 R-DME-1227986 Signaling by ERBB2 XP_046664456.1 Q94918 R-DME-1236394 Signaling by ERBB4 XP_046664456.1 Q94918 R-DME-1250196 SHC1 events in ERBB2 signaling XP_046664456.1 Q94918 R-DME-1250342 PI3K events in ERBB4 signaling XP_046664456.1 Q94918 R-DME-1250347 SHC1 events in ERBB4 signaling XP_046664456.1 Q94918 R-DME-1257604 PIP3 activates AKT signaling XP_046664456.1 Q94918 R-DME-1358803 Downregulation of ERBB2:ERBB3 signaling XP_046664456.1 Q94918 R-DME-162582 Signal Transduction XP_046664456.1 Q94918 R-DME-1963640 GRB2 events in ERBB2 signaling XP_046664456.1 Q94918 R-DME-1963642 PI3K events in ERBB2 signaling XP_046664456.1 Q94918 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046664456.1 Q94918 R-DME-5673001 RAF/MAP kinase cascade XP_046664456.1 Q94918 R-DME-5683057 MAPK family signaling cascades XP_046664456.1 Q94918 R-DME-5684996 MAPK1/MAPK3 signaling XP_046664456.1 Q94918 R-DME-6785631 ERBB2 Regulates Cell Motility XP_046664456.1 Q94918 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046664456.1 Q94918 R-DME-8863795 Downregulation of ERBB2 signaling XP_046664456.1 Q94918 R-DME-9006925 Intracellular signaling by second messengers XP_046664456.1 Q94918 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046672296.1 P29310 R-DME-109582 Hemostasis XP_046672296.1 P29310 R-DME-1280218 Adaptive Immune System XP_046672296.1 P29310 R-DME-157118 Signaling by NOTCH XP_046672296.1 P29310 R-DME-162582 Signal Transduction XP_046672296.1 P29310 R-DME-1640170 Cell Cycle XP_046672296.1 P29310 R-DME-165159 MTOR signalling XP_046672296.1 P29310 R-DME-166520 Signaling by NTRKs XP_046672296.1 P29310 R-DME-168256 Immune System XP_046672296.1 P29310 R-DME-169893 Prolonged ERK activation events XP_046672296.1 P29310 R-DME-170968 Frs2-mediated activation XP_046672296.1 P29310 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046672296.1 P29310 R-DME-187687 Signalling to ERKs XP_046672296.1 P29310 R-DME-194315 Signaling by Rho GTPases XP_046672296.1 P29310 R-DME-195258 RHO GTPase Effectors XP_046672296.1 P29310 R-DME-195721 Signaling by WNT XP_046672296.1 P29310 R-DME-201681 TCF dependent signaling in response to WNT XP_046672296.1 P29310 R-DME-2028269 Signaling by Hippo XP_046672296.1 P29310 R-DME-212436 Generic Transcription Pathway XP_046672296.1 P29310 R-DME-3700989 Transcriptional Regulation by TP53 XP_046672296.1 P29310 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046672296.1 P29310 R-DME-388841 Regulation of T cell activation by CD28 family XP_046672296.1 P29310 R-DME-389948 Co-inhibition by PD-1 XP_046672296.1 P29310 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046672296.1 P29310 R-DME-390146 Hippo/Warts pathway XP_046672296.1 P29310 R-DME-390150 DS ligand bound to FT receptor XP_046672296.1 P29310 R-DME-392517 Rap1 signalling XP_046672296.1 P29310 R-DME-430116 GP1b-IX-V activation signalling XP_046672296.1 P29310 R-DME-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA XP_046672296.1 P29310 R-DME-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA XP_046672296.1 P29310 R-DME-450531 Regulation of mRNA stability by proteins that bind AU-rich elements XP_046672296.1 P29310 R-DME-450604 KSRP (KHSRP) binds and destabilizes mRNA XP_046672296.1 P29310 R-DME-5252538 Drosophila signaling pathways XP_046672296.1 P29310 R-DME-5625740 RHO GTPases activate PKNs XP_046672296.1 P29310 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046672296.1 P29310 R-DME-5673000 RAF activation XP_046672296.1 P29310 R-DME-5673001 RAF/MAP kinase cascade XP_046672296.1 P29310 R-DME-5674135 MAP2K and MAPK activation XP_046672296.1 P29310 R-DME-5675221 Negative regulation of MAPK pathway XP_046672296.1 P29310 R-DME-5683057 MAPK family signaling cascades XP_046672296.1 P29310 R-DME-5684996 MAPK1/MAPK3 signaling XP_046672296.1 P29310 R-DME-6791312 TP53 Regulates Transcription of Cell Cycle Genes XP_046672296.1 P29310 R-DME-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest XP_046672296.1 P29310 R-DME-69473 G2/M DNA damage checkpoint XP_046672296.1 P29310 R-DME-69481 G2/M Checkpoints XP_046672296.1 P29310 R-DME-69620 Cell Cycle Checkpoints XP_046672296.1 P29310 R-DME-73857 RNA Polymerase II Transcription XP_046672296.1 P29310 R-DME-74160 Gene expression (Transcription) XP_046672296.1 P29310 R-DME-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex XP_046672296.1 P29310 R-DME-76002 Platelet activation, signaling and aggregation XP_046672296.1 P29310 R-DME-8953854 Metabolism of RNA XP_046672296.1 P29310 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046672296.1 P29310 R-DME-9013694 Signaling by NOTCH4 XP_046672296.1 P29310 R-DME-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus XP_046672296.1 P29310 R-DME-9614085 FOXO-mediated transcription XP_046672296.1 P29310 R-DME-9614399 Regulation of localization of FOXO transcription factors XP_046672296.1 P29310 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046672296.1 P29310 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046672296.1 P29310 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046672296.1 P29310 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046658831.1 Q24151 R-DME-1059683 Interleukin-6 signaling XP_046658831.1 Q24151 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046658831.1 Q24151 R-DME-1236394 Signaling by ERBB4 XP_046658831.1 Q24151 R-DME-1251985 Nuclear signaling by ERBB4 XP_046658831.1 Q24151 R-DME-1280215 Cytokine Signaling in Immune system XP_046658831.1 Q24151 R-DME-162582 Signal Transduction XP_046658831.1 Q24151 R-DME-168249 Innate Immune System XP_046658831.1 Q24151 R-DME-168256 Immune System XP_046658831.1 Q24151 R-DME-1834941 STING mediated induction of host immune responses XP_046658831.1 Q24151 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046658831.1 Q24151 R-DME-186763 Downstream signal transduction XP_046658831.1 Q24151 R-DME-186797 Signaling by PDGF XP_046658831.1 Q24151 R-DME-201556 Signaling by ALK XP_046658831.1 Q24151 R-DME-209228 Formation of the activated STAT92E dimer and transport to the nucleus XP_046658831.1 Q24151 R-DME-209394 Transcriptional activtion and repression of REL-68 target genes XP_046658831.1 Q24151 R-DME-209405 JAK/STAT pathway XP_046658831.1 Q24151 R-DME-209459 Imd pathway XP_046658831.1 Q24151 R-DME-210671 Transcriptional repression by nuclear factors XP_046658831.1 Q24151 R-DME-210688 Dephosphorylation by PTP61F phosphatases XP_046658831.1 Q24151 R-DME-210693 STAT92E dimer dephosphorylated in the nucleus and transported to the cytosol XP_046658831.1 Q24151 R-DME-3249367 STAT6-mediated induction of chemokines XP_046658831.1 Q24151 R-DME-446652 Interleukin-1 family signaling XP_046658831.1 Q24151 R-DME-447115 Interleukin-12 family signaling XP_046658831.1 Q24151 R-DME-449147 Signaling by Interleukins XP_046658831.1 Q24151 R-DME-451927 Interleukin-2 family signaling XP_046658831.1 Q24151 R-DME-5252538 Drosophila signaling pathways XP_046658831.1 Q24151 R-DME-6783589 Interleukin-6 family signaling XP_046658831.1 Q24151 R-DME-6783783 Interleukin-10 signaling XP_046658831.1 Q24151 R-DME-6785807 Interleukin-4 and Interleukin-13 signaling XP_046658831.1 Q24151 R-DME-877300 Interferon gamma signaling XP_046658831.1 Q24151 R-DME-877312 Regulation of IFNG signaling XP_046658831.1 Q24151 R-DME-8854691 Interleukin-20 family signaling XP_046658831.1 Q24151 R-DME-8953897 Cellular responses to stimuli XP_046658831.1 Q24151 R-DME-8983432 Interleukin-15 signaling XP_046658831.1 Q24151 R-DME-8984722 Interleukin-35 Signalling XP_046658831.1 Q24151 R-DME-8985947 Interleukin-9 signaling XP_046658831.1 Q24151 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046658831.1 Q24151 R-DME-9008059 Interleukin-37 signaling XP_046658831.1 Q24151 R-DME-9020591 Interleukin-12 signaling XP_046658831.1 Q24151 R-DME-9020933 Interleukin-23 signaling XP_046658831.1 Q24151 R-DME-9020956 Interleukin-27 signaling XP_046658831.1 Q24151 R-DME-909733 Interferon alpha/beta signaling XP_046658831.1 Q24151 R-DME-913531 Interferon Signaling XP_046658831.1 Q24151 R-DME-9701898 STAT3 nuclear events downstream of ALK signaling XP_046658831.1 Q24151 R-DME-9833482 PKR-mediated signaling XP_046658831.1 Q24151 R-DME-9855142 Cellular responses to mechanical stimuli XP_046658831.1 Q24151 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046658831.1 Q24151 R-DME-9860931 Response of endothelial cells to shear stress XP_046669164.1 Q9VDT9 R-DME-109704 PI3K Cascade XP_046669164.1 Q9VDT9 R-DME-112399 IRS-mediated signalling XP_046669164.1 Q9VDT9 R-DME-1257604 PIP3 activates AKT signaling XP_046669164.1 Q9VDT9 R-DME-1307965 betaKlotho-mediated ligand binding XP_046669164.1 Q9VDT9 R-DME-162582 Signal Transduction XP_046669164.1 Q9VDT9 R-DME-189200 Cellular hexose transport XP_046669164.1 Q9VDT9 R-DME-190236 Signaling by FGFR XP_046669164.1 Q9VDT9 R-DME-190239 FGFR3 ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190241 FGFR2 ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190242 FGFR1 ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190322 FGFR4 ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190370 FGFR1b ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190371 FGFR3b ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190372 FGFR3c ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190373 FGFR1c ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190374 FGFR1c and Klotho ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190375 FGFR2c ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-190377 FGFR2b ligand binding and activation XP_046669164.1 Q9VDT9 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046669164.1 Q9VDT9 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046669164.1 Q9VDT9 R-DME-2428924 IGF1R signaling cascade XP_046669164.1 Q9VDT9 R-DME-2428928 IRS-related events triggered by IGF1R XP_046669164.1 Q9VDT9 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046669164.1 Q9VDT9 R-DME-382551 Transport of small molecules XP_046669164.1 Q9VDT9 R-DME-392499 Metabolism of proteins XP_046669164.1 Q9VDT9 R-DME-425407 SLC-mediated transmembrane transport XP_046669164.1 Q9VDT9 R-DME-5654219 Phospholipase C-mediated cascade: FGFR1 XP_046669164.1 Q9VDT9 R-DME-5654221 Phospholipase C-mediated cascade; FGFR2 XP_046669164.1 Q9VDT9 R-DME-5654227 Phospholipase C-mediated cascade; FGFR3 XP_046669164.1 Q9VDT9 R-DME-5654228 Phospholipase C-mediated cascade; FGFR4 XP_046669164.1 Q9VDT9 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046669164.1 Q9VDT9 R-DME-5654688 SHC-mediated cascade:FGFR1 XP_046669164.1 Q9VDT9 R-DME-5654689 PI-3K cascade:FGFR1 XP_046669164.1 Q9VDT9 R-DME-5654693 FRS-mediated FGFR1 signaling XP_046669164.1 Q9VDT9 R-DME-5654695 PI-3K cascade:FGFR2 XP_046669164.1 Q9VDT9 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046669164.1 Q9VDT9 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046669164.1 Q9VDT9 R-DME-5654700 FRS-mediated FGFR2 signaling XP_046669164.1 Q9VDT9 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046669164.1 Q9VDT9 R-DME-5654706 FRS-mediated FGFR3 signaling XP_046669164.1 Q9VDT9 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046669164.1 Q9VDT9 R-DME-5654710 PI-3K cascade:FGFR3 XP_046669164.1 Q9VDT9 R-DME-5654712 FRS-mediated FGFR4 signaling XP_046669164.1 Q9VDT9 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046669164.1 Q9VDT9 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046669164.1 Q9VDT9 R-DME-5654720 PI-3K cascade:FGFR4 XP_046669164.1 Q9VDT9 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046669164.1 Q9VDT9 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046669164.1 Q9VDT9 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046669164.1 Q9VDT9 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046669164.1 Q9VDT9 R-DME-5654736 Signaling by FGFR1 XP_046669164.1 Q9VDT9 R-DME-5654738 Signaling by FGFR2 XP_046669164.1 Q9VDT9 R-DME-5654741 Signaling by FGFR3 XP_046669164.1 Q9VDT9 R-DME-5654743 Signaling by FGFR4 XP_046669164.1 Q9VDT9 R-DME-5658623 FGFRL1 modulation of FGFR1 signaling XP_046669164.1 Q9VDT9 R-DME-5673001 RAF/MAP kinase cascade XP_046669164.1 Q9VDT9 R-DME-5683057 MAPK family signaling cascades XP_046669164.1 Q9VDT9 R-DME-5684996 MAPK1/MAPK3 signaling XP_046669164.1 Q9VDT9 R-DME-597592 Post-translational protein modification XP_046669164.1 Q9VDT9 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046669164.1 Q9VDT9 R-DME-74751 Insulin receptor signalling cascade XP_046669164.1 Q9VDT9 R-DME-74752 Signaling by Insulin receptor XP_046669164.1 Q9VDT9 R-DME-8957275 Post-translational protein phosphorylation XP_046669164.1 Q9VDT9 R-DME-9006925 Intracellular signaling by second messengers XP_046669164.1 Q9VDT9 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046660206.1 Q9VBP9 R-DME-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template XP_046660206.1 Q9VBP9 R-DME-110320 Translesion Synthesis by POLH XP_046660206.1 Q9VBP9 R-DME-2262752 Cellular responses to stress XP_046660206.1 Q9VBP9 R-DME-392499 Metabolism of proteins XP_046660206.1 Q9VBP9 R-DME-597592 Post-translational protein modification XP_046660206.1 Q9VBP9 R-DME-73893 DNA Damage Bypass XP_046660206.1 Q9VBP9 R-DME-73894 DNA Repair XP_046660206.1 Q9VBP9 R-DME-8951664 Neddylation XP_046660206.1 Q9VBP9 R-DME-8953897 Cellular responses to stimuli XP_046660206.1 Q9VBP9 R-DME-9711123 Cellular response to chemical stress XP_046660206.1 Q9VBP9 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046668783.1 O46036 R-DME-1500931 Cell-Cell communication XP_046668783.1 O46036 R-DME-162582 Signal Transduction XP_046668783.1 O46036 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046668783.1 O46036 R-DME-195721 Signaling by WNT XP_046668783.1 O46036 R-DME-201681 TCF dependent signaling in response to WNT XP_046668783.1 O46036 R-DME-2990846 SUMOylation XP_046668783.1 O46036 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046668783.1 O46036 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046668783.1 O46036 R-DME-3899300 SUMOylation of transcription cofactors XP_046668783.1 O46036 R-DME-392499 Metabolism of proteins XP_046668783.1 O46036 R-DME-418990 Adherens junctions interactions XP_046668783.1 O46036 R-DME-421270 Cell-cell junction organization XP_046668783.1 O46036 R-DME-446728 Cell junction organization XP_046668783.1 O46036 R-DME-4641265 Repression of WNT target genes XP_046668783.1 O46036 R-DME-597592 Post-translational protein modification XP_046668783.1 O46036 R-DME-9759476 Regulation of Homotypic Cell-Cell Adhesion XP_046668783.1 O46036 R-DME-9764265 Regulation of CDH1 Expression and Function XP_046668783.1 O46036 R-DME-9764274 Regulation of Expression and Function of Type I Classical Cadherins XP_046668783.1 O46036 R-DME-9764560 Regulation of CDH1 Gene Transcription XP_046668783.1 O46036 R-DME-9764725 Negative Regulation of CDH1 Gene Transcription XP_046658257.1 Q961U0 R-DME-392499 Metabolism of proteins XP_046658257.1 Q961U0 R-DME-446203 Asparagine N-linked glycosylation XP_046658257.1 Q961U0 R-DME-597592 Post-translational protein modification XP_046658257.1 Q961U0 R-DME-948021 Transport to the Golgi and subsequent modification XP_046658257.1 Q961U0 R-DME-975576 N-glycan antennae elongation in the medial/trans-Golgi XP_046658257.1 Q961U0 R-DME-975578 Reactions specific to the complex N-glycan synthesis pathway XP_046673107.1 Q03043 R-DME-1280218 Adaptive Immune System XP_046673107.1 Q03043 R-DME-1430728 Metabolism XP_046673107.1 Q03043 R-DME-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation XP_046673107.1 Q03043 R-DME-162582 Signal Transduction XP_046673107.1 Q03043 R-DME-168256 Immune System XP_046673107.1 Q03043 R-DME-196854 Metabolism of vitamins and cofactors XP_046673107.1 Q03043 R-DME-392517 Rap1 signalling XP_046673107.1 Q03043 R-DME-5673001 RAF/MAP kinase cascade XP_046673107.1 Q03043 R-DME-5683057 MAPK family signaling cascades XP_046673107.1 Q03043 R-DME-5684996 MAPK1/MAPK3 signaling XP_046673107.1 Q03043 R-DME-8978934 Metabolism of cofactors XP_046673107.1 Q03043 R-DME-9648002 RAS processing XP_046666239.1 Q9VWI6 R-DME-112316 Neuronal System XP_046666239.1 Q9VWI6 R-DME-6794362 Protein-protein interactions at synapses XP_046666239.1 Q9VWI6 R-DME-8849932 Synaptic adhesion-like molecules XP_046678292.1 M9PHQ2 R-DME-212436 Generic Transcription Pathway XP_046678292.1 M9PHQ2 R-DME-2990846 SUMOylation XP_046678292.1 M9PHQ2 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046678292.1 M9PHQ2 R-DME-350054 Notch-HLH transcription pathway XP_046678292.1 M9PHQ2 R-DME-392499 Metabolism of proteins XP_046678292.1 M9PHQ2 R-DME-4090294 SUMOylation of intracellular receptors XP_046678292.1 M9PHQ2 R-DME-4551638 SUMOylation of chromatin organization proteins XP_046678292.1 M9PHQ2 R-DME-597592 Post-translational protein modification XP_046678292.1 M9PHQ2 R-DME-73857 RNA Polymerase II Transcription XP_046678292.1 M9PHQ2 R-DME-74160 Gene expression (Transcription) XP_046678292.1 M9PHQ2 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046678292.1 M9PHQ2 R-DME-8951936 RUNX3 regulates p14-ARF XP_046683733.1 Q9VTG7 R-DME-1430728 Metabolism XP_046683733.1 Q9VTG7 R-DME-1630316 Glycosaminoglycan metabolism XP_046683733.1 Q9VTG7 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046683733.1 Q9VTG7 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046679442.1 Q7KUZ9 R-DME-1430728 Metabolism XP_046679442.1 Q7KUZ9 R-DME-1630316 Glycosaminoglycan metabolism XP_046679442.1 Q7KUZ9 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046679442.1 Q7KUZ9 R-DME-2022870 CS-GAG biosynthesis XP_046679442.1 Q7KUZ9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046670040.1 Q9VSW1 R-DME-1430728 Metabolism XP_046670040.1 Q9VSW1 R-DME-156580 Phase II - Conjugation of compounds XP_046670040.1 Q9VSW1 R-DME-156588 Glucuronidation XP_046670040.1 Q9VSW1 R-DME-173599 Formation of the active cofactor, UDP-glucuronate XP_046670040.1 Q9VSW1 R-DME-211859 Biological oxidations XP_046670040.1 Q9VSW1 R-DME-3322077 Glycogen synthesis XP_046670040.1 Q9VSW1 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046670040.1 Q9VSW1 R-DME-8982491 Glycogen metabolism XP_046663576.1 Q6WV19 R-DME-199991 Membrane Trafficking XP_046663576.1 Q6WV19 R-DME-392499 Metabolism of proteins XP_046663576.1 Q6WV19 R-DME-5173105 O-linked glycosylation XP_046663576.1 Q6WV19 R-DME-5653656 Vesicle-mediated transport XP_046663576.1 Q6WV19 R-DME-597592 Post-translational protein modification XP_046663576.1 Q6WV19 R-DME-6811436 COPI-independent Golgi-to-ER retrograde traffic XP_046663576.1 Q6WV19 R-DME-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic XP_046663576.1 Q6WV19 R-DME-8856688 Golgi-to-ER retrograde transport XP_046663576.1 Q6WV19 R-DME-913709 O-linked glycosylation of mucins XP_046680330.1 Q9W2H8 R-DME-1430728 Metabolism XP_046680330.1 Q9W2H8 R-DME-168249 Innate Immune System XP_046680330.1 Q9W2H8 R-DME-168256 Immune System XP_046680330.1 Q9W2H8 R-DME-6798695 Neutrophil degranulation XP_046680330.1 Q9W2H8 R-DME-70221 Glycogen breakdown (glycogenolysis) XP_046680330.1 Q9W2H8 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046680330.1 Q9W2H8 R-DME-8982491 Glycogen metabolism XP_046664033.1 P36179 R-DME-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 XP_046664033.1 P36179 R-DME-113510 E2F mediated regulation of DNA replication XP_046664033.1 P36179 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046664033.1 P36179 R-DME-1257604 PIP3 activates AKT signaling XP_046664033.1 P36179 R-DME-1280215 Cytokine Signaling in Immune system XP_046664033.1 P36179 R-DME-1280218 Adaptive Immune System XP_046664033.1 P36179 R-DME-1295596 Spry regulation of FGF signaling XP_046664033.1 P36179 R-DME-162582 Signal Transduction XP_046664033.1 P36179 R-DME-1640170 Cell Cycle XP_046664033.1 P36179 R-DME-168256 Immune System XP_046664033.1 P36179 R-DME-190236 Signaling by FGFR XP_046664033.1 P36179 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046664033.1 P36179 R-DME-195721 Signaling by WNT XP_046664033.1 P36179 R-DME-196299 Beta-catenin phosphorylation cascade XP_046664033.1 P36179 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046664033.1 P36179 R-DME-209155 Phosphorylation of AXN and APC XP_046664033.1 P36179 R-DME-209159 Assembly of the CI containing complexes XP_046664033.1 P36179 R-DME-209190 Phosphorylation of CI XP_046664033.1 P36179 R-DME-209214 Phosphorylation of SMO XP_046664033.1 P36179 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046664033.1 P36179 R-DME-209392 Hedgehog pathway XP_046664033.1 P36179 R-DME-209396 Phosphorylation of ARM XP_046664033.1 P36179 R-DME-209412 Wingless pathway XP_046664033.1 P36179 R-DME-209413 Assembly of the 'destruction complex' XP_046664033.1 P36179 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046664033.1 P36179 R-DME-209441 WG ligand not bound to FZ receptors XP_046664033.1 P36179 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046664033.1 P36179 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046664033.1 P36179 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046664033.1 P36179 R-DME-209469 WG ligand bound to FZ receptors XP_046664033.1 P36179 R-DME-216217 Activation of SMO XP_046664033.1 P36179 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046664033.1 P36179 R-DME-2995383 Initiation of Nuclear Envelope (NE) Reformation XP_046664033.1 P36179 R-DME-2995410 Nuclear Envelope (NE) Reassembly XP_046664033.1 P36179 R-DME-388841 Regulation of T cell activation by CD28 family XP_046664033.1 P36179 R-DME-389513 Co-inhibition by CTLA4 XP_046664033.1 P36179 R-DME-432553 Phosphorylation of PER and TIM XP_046664033.1 P36179 R-DME-432620 Dephosphorylation of PER XP_046664033.1 P36179 R-DME-432626 Circadian Clock pathway XP_046664033.1 P36179 R-DME-453274 Mitotic G2-G2/M phases XP_046664033.1 P36179 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046664033.1 P36179 R-DME-5252538 Drosophila signaling pathways XP_046664033.1 P36179 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046664033.1 P36179 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046664033.1 P36179 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046664033.1 P36179 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046664033.1 P36179 R-DME-5654736 Signaling by FGFR1 XP_046664033.1 P36179 R-DME-5654738 Signaling by FGFR2 XP_046664033.1 P36179 R-DME-5654741 Signaling by FGFR3 XP_046664033.1 P36179 R-DME-5654743 Signaling by FGFR4 XP_046664033.1 P36179 R-DME-5673000 RAF activation XP_046664033.1 P36179 R-DME-5673001 RAF/MAP kinase cascade XP_046664033.1 P36179 R-DME-5675221 Negative regulation of MAPK pathway XP_046664033.1 P36179 R-DME-5683057 MAPK family signaling cascades XP_046664033.1 P36179 R-DME-5684996 MAPK1/MAPK3 signaling XP_046664033.1 P36179 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046664033.1 P36179 R-DME-68882 Mitotic Anaphase XP_046664033.1 P36179 R-DME-68886 M Phase XP_046664033.1 P36179 R-DME-69206 G1/S Transition XP_046664033.1 P36179 R-DME-69231 Cyclin D associated events in G1 XP_046664033.1 P36179 R-DME-69236 G1 Phase XP_046664033.1 P36179 R-DME-69273 Cyclin A/B1/B2 associated events during G2/M transition XP_046664033.1 P36179 R-DME-69275 G2/M Transition XP_046664033.1 P36179 R-DME-69278 Cell Cycle, Mitotic XP_046664033.1 P36179 R-DME-8953854 Metabolism of RNA XP_046664033.1 P36179 R-DME-8953897 Cellular responses to stimuli XP_046664033.1 P36179 R-DME-9006925 Intracellular signaling by second messengers XP_046664033.1 P36179 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046664033.1 P36179 R-DME-913531 Interferon Signaling XP_046664033.1 P36179 R-DME-927802 Nonsense-Mediated Decay (NMD) XP_046664033.1 P36179 R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) XP_046664033.1 P36179 R-DME-9833482 PKR-mediated signaling XP_046664033.1 P36179 R-DME-9855142 Cellular responses to mechanical stimuli XP_046664033.1 P36179 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046664033.1 P36179 R-DME-9860931 Response of endothelial cells to shear stress XP_046670443.1 Q9Y169 R-DME-1430728 Metabolism XP_046670443.1 Q9Y169 R-DME-1630316 Glycosaminoglycan metabolism XP_046670443.1 Q9Y169 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046670443.1 Q9Y169 R-DME-2022928 HS-GAG biosynthesis XP_046670443.1 Q9Y169 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046663548.1 Q9XTL9 R-DME-1430728 Metabolism XP_046663548.1 Q9XTL9 R-DME-168249 Innate Immune System XP_046663548.1 Q9XTL9 R-DME-168256 Immune System XP_046663548.1 Q9XTL9 R-DME-6798695 Neutrophil degranulation XP_046663548.1 Q9XTL9 R-DME-70221 Glycogen breakdown (glycogenolysis) XP_046663548.1 Q9XTL9 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046663548.1 Q9XTL9 R-DME-8982491 Glycogen metabolism XP_046677317.1 B7YZP6 R-DME-168249 Innate Immune System XP_046677317.1 B7YZP6 R-DME-168256 Immune System XP_046677317.1 B7YZP6 R-DME-6798695 Neutrophil degranulation XP_046658995.1 P21525 R-DME-1280215 Cytokine Signaling in Immune system XP_046658995.1 P21525 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046658995.1 P21525 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046658995.1 P21525 R-DME-166166 MyD88-independent TLR4 cascade XP_046658995.1 P21525 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046658995.1 P21525 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046658995.1 P21525 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046658995.1 P21525 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046658995.1 P21525 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046658995.1 P21525 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046658995.1 P21525 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046658995.1 P21525 R-DME-168249 Innate Immune System XP_046658995.1 P21525 R-DME-168256 Immune System XP_046658995.1 P21525 R-DME-168898 Toll-like Receptor Cascades XP_046658995.1 P21525 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046658995.1 P21525 R-DME-209394 Transcriptional activtion and repression of REL-68 target genes XP_046658995.1 P21525 R-DME-209409 Formation of the nuclear AP-1 transcription factor 'scaffolding complex' XP_046658995.1 P21525 R-DME-209425 Transcriptional activtion by AP-1 transcription factor XP_046658995.1 P21525 R-DME-209459 Imd pathway XP_046658995.1 P21525 R-DME-2262752 Cellular responses to stress XP_046658995.1 P21525 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046658995.1 P21525 R-DME-2559580 Oxidative Stress Induced Senescence XP_046658995.1 P21525 R-DME-2559583 Cellular Senescence XP_046658995.1 P21525 R-DME-2871796 FCERI mediated MAPK activation XP_046658995.1 P21525 R-DME-350431 Planar Cell Polarity pathway XP_046658995.1 P21525 R-DME-448424 Interleukin-17 signaling XP_046658995.1 P21525 R-DME-449147 Signaling by Interleukins XP_046658995.1 P21525 R-DME-450282 MAPK targets/ Nuclear events mediated by MAP kinases XP_046658995.1 P21525 R-DME-450294 MAP kinase activation XP_046658995.1 P21525 R-DME-450341 Activation of the AP-1 family of transcription factors XP_046658995.1 P21525 R-DME-450724 JNK signalling XP_046658995.1 P21525 R-DME-450736 Activation of Downstream Effectors XP_046658995.1 P21525 R-DME-5252538 Drosophila signaling pathways XP_046658995.1 P21525 R-DME-8953897 Cellular responses to stimuli XP_046658995.1 P21525 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046658995.1 P21525 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046658995.1 P21525 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046658995.1 P21525 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046661570.1 Q7K2X1 R-DME-1280218 Adaptive Immune System XP_046661570.1 Q7K2X1 R-DME-168256 Immune System XP_046661570.1 Q7K2X1 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046661570.1 Q7K2X1 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046672302.1 A0A0B4LFY9 R-DME-168249 Innate Immune System XP_046672302.1 A0A0B4LFY9 R-DME-168256 Immune System XP_046672302.1 A0A0B4LFY9 R-DME-1834941 STING mediated induction of host immune responses XP_046672302.1 A0A0B4LFY9 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046672302.1 A0A0B4LFY9 R-DME-3134975 Regulation of innate immune responses to cytosolic DNA XP_046672302.1 A0A0B4LFY9 R-DME-3249367 STAT6-mediated induction of chemokines XP_046672302.1 A0A0B4LFY9 R-DME-6798695 Neutrophil degranulation XP_046684156.1 Q02936 R-DME-162582 Signal Transduction XP_046684156.1 Q02936 R-DME-209338 Assembly of the 'signalling complexes' XP_046684156.1 Q02936 R-DME-209392 Hedgehog pathway XP_046684156.1 Q02936 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046684156.1 Q02936 R-DME-209471 Formation and transport of the N-HH ligand XP_046684156.1 Q02936 R-DME-5252538 Drosophila signaling pathways XP_046684156.1 Q02936 R-DME-5358346 Hedgehog ligand biogenesis XP_046684156.1 Q02936 R-DME-5358351 Signaling by Hedgehog XP_046684156.1 Q02936 R-DME-5362798 Release of Hh-Np from the secreting cell XP_046684156.1 Q02936 R-DME-5632681 Ligand-receptor interactions XP_046684156.1 Q02936 R-DME-5632684 Hedgehog 'on' state XP_046674780.1 Q94920 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046674780.1 Q94920 R-DME-1430728 Metabolism XP_046674780.1 Q94920 R-DME-1632852 Macroautophagy XP_046674780.1 Q94920 R-DME-392499 Metabolism of proteins XP_046674780.1 Q94920 R-DME-5205647 Mitophagy XP_046674780.1 Q94920 R-DME-5205685 PINK1-PRKN Mediated Mitophagy XP_046674780.1 Q94920 R-DME-5688426 Deubiquitination XP_046674780.1 Q94920 R-DME-5689880 Ub-specific processing proteases XP_046674780.1 Q94920 R-DME-597592 Post-translational protein modification XP_046674780.1 Q94920 R-DME-70268 Pyruvate metabolism XP_046674780.1 Q94920 R-DME-9612973 Autophagy XP_046674780.1 Q94920 R-DME-9663891 Selective autophagy XP_046673538.1 Q8SX83 R-DME-162582 Signal Transduction XP_046673538.1 Q8SX83 R-DME-194315 Signaling by Rho GTPases XP_046673538.1 Q8SX83 R-DME-9012999 RHO GTPase cycle XP_046673538.1 Q8SX83 R-DME-9013422 RHOBTB1 GTPase cycle XP_046673538.1 Q8SX83 R-DME-9706574 RHOBTB GTPase Cycle XP_046673538.1 Q8SX83 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046686244.1 Q8IRY7 R-DME-109581 Apoptosis XP_046686244.1 Q8IRY7 R-DME-109606 Intrinsic Pathway for Apoptosis XP_046686244.1 Q8IRY7 R-DME-111458 Formation of apoptosome XP_046686244.1 Q8IRY7 R-DME-111459 Activation of caspases through apoptosome-mediated cleavage XP_046686244.1 Q8IRY7 R-DME-111461 Cytochrome c-mediated apoptotic response XP_046686244.1 Q8IRY7 R-DME-111471 Apoptotic factor-mediated response XP_046686244.1 Q8IRY7 R-DME-1257604 PIP3 activates AKT signaling XP_046686244.1 Q8IRY7 R-DME-162582 Signal Transduction XP_046686244.1 Q8IRY7 R-DME-168249 Innate Immune System XP_046686244.1 Q8IRY7 R-DME-168256 Immune System XP_046686244.1 Q8IRY7 R-DME-198323 AKT phosphorylates targets in the cytosol XP_046686244.1 Q8IRY7 R-DME-209438 Formation of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046686244.1 Q8IRY7 R-DME-209459 Imd pathway XP_046686244.1 Q8IRY7 R-DME-209465 Catalytic processing of the nuclear factor, REL XP_046686244.1 Q8IRY7 R-DME-212436 Generic Transcription Pathway XP_046686244.1 Q8IRY7 R-DME-214397 Assembly of the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046686244.1 Q8IRY7 R-DME-214399 Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046686244.1 Q8IRY7 R-DME-214411 REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex' XP_046686244.1 Q8IRY7 R-DME-214416 Phosphorylated REL is cleaved by and dissociates from DREDD XP_046686244.1 Q8IRY7 R-DME-3700989 Transcriptional Regulation by TP53 XP_046686244.1 Q8IRY7 R-DME-5252538 Drosophila signaling pathways XP_046686244.1 Q8IRY7 R-DME-5357801 Programmed Cell Death XP_046686244.1 Q8IRY7 R-DME-5633008 TP53 Regulates Transcription of Cell Death Genes XP_046686244.1 Q8IRY7 R-DME-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases XP_046686244.1 Q8IRY7 R-DME-73857 RNA Polymerase II Transcription XP_046686244.1 Q8IRY7 R-DME-74160 Gene expression (Transcription) XP_046686244.1 Q8IRY7 R-DME-9006925 Intracellular signaling by second messengers XP_046686244.1 Q8IRY7 R-DME-9627069 Regulation of the apoptosome activity XP_046686244.1 Q8IRY7 R-DME-9686114 Non-canonical inflammasome activation XP_046686244.1 Q8IRY7 R-DME-9948001 CASP4 inflammasome assembly XP_046686244.1 Q8IRY7 R-DME-9948011 CASP5 inflammasome assembly XP_046658256.1 Q9VAN7 R-DME-1430728 Metabolism XP_046658256.1 Q9VAN7 R-DME-168249 Innate Immune System XP_046658256.1 Q9VAN7 R-DME-168256 Immune System XP_046658256.1 Q9VAN7 R-DME-6798695 Neutrophil degranulation XP_046658256.1 Q9VAN7 R-DME-70171 Glycolysis XP_046658256.1 Q9VAN7 R-DME-70263 Gluconeogenesis XP_046658256.1 Q9VAN7 R-DME-70326 Glucose metabolism XP_046658256.1 Q9VAN7 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046665678.1 Q2PDR0 R-DME-162699 Synthesis of dolichyl-phosphate mannose XP_046665678.1 Q2PDR0 R-DME-163125 Post-translational modification: synthesis of GPI-anchored proteins XP_046665678.1 Q2PDR0 R-DME-392499 Metabolism of proteins XP_046665678.1 Q2PDR0 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046665678.1 Q2PDR0 R-DME-446203 Asparagine N-linked glycosylation XP_046665678.1 Q2PDR0 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046665678.1 Q2PDR0 R-DME-597592 Post-translational protein modification XP_046673103.1 P07486 R-DME-1430728 Metabolism XP_046673103.1 P07486 R-DME-70171 Glycolysis XP_046673103.1 P07486 R-DME-70263 Gluconeogenesis XP_046673103.1 P07486 R-DME-70326 Glucose metabolism XP_046673103.1 P07486 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046676171.1 Q8IPY3 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046676171.1 Q8IPY3 R-DME-1430728 Metabolism XP_046676171.1 Q8IPY3 R-DME-389661 Glyoxylate metabolism and glycine degradation XP_046676171.1 Q8IPY3 R-DME-611105 Respiratory electron transport XP_046676171.1 Q8IPY3 R-DME-71291 Metabolism of amino acids and derivatives XP_046676171.1 Q8IPY3 R-DME-8963693 Aspartate and asparagine metabolism XP_046676171.1 Q8IPY3 R-DME-8964539 Glutamate and glutamine metabolism XP_046676171.1 Q8IPY3 R-DME-9856872 Malate-aspartate shuttle XP_046661151.1 Q9NII1 R-DME-75064 mRNA Editing: A to I Conversion XP_046661151.1 Q9NII1 R-DME-75072 mRNA Editing XP_046661151.1 Q9NII1 R-DME-75102 C6 deamination of adenosine XP_046661151.1 Q9NII1 R-DME-77042 Formation of editosomes by ADAR proteins XP_046661151.1 Q9NII1 R-DME-8953854 Metabolism of RNA XP_046671947.1 O77430 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046671947.1 O77430 R-DME-1169091 Activation of NF-kappaB in B cells XP_046671947.1 O77430 R-DME-1280215 Cytokine Signaling in Immune system XP_046671947.1 O77430 R-DME-1280218 Adaptive Immune System XP_046671947.1 O77430 R-DME-162582 Signal Transduction XP_046671947.1 O77430 R-DME-1640170 Cell Cycle XP_046671947.1 O77430 R-DME-168249 Innate Immune System XP_046671947.1 O77430 R-DME-168256 Immune System XP_046671947.1 O77430 R-DME-174113 SCF-beta-TrCP mediated degradation of Emi1 XP_046671947.1 O77430 R-DME-174143 APC/C-mediated degradation of cell cycle proteins XP_046671947.1 O77430 R-DME-176408 Regulation of APC/C activators between G1/S and early anaphase XP_046671947.1 O77430 R-DME-187577 SCF(Skp2)-mediated degradation of p27/p21 XP_046671947.1 O77430 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046671947.1 O77430 R-DME-195721 Signaling by WNT XP_046671947.1 O77430 R-DME-202403 TCR signaling XP_046671947.1 O77430 R-DME-202424 Downstream TCR signaling XP_046671947.1 O77430 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046671947.1 O77430 R-DME-209392 Hedgehog pathway XP_046671947.1 O77430 R-DME-209412 Wingless pathway XP_046671947.1 O77430 R-DME-209441 WG ligand not bound to FZ receptors XP_046671947.1 O77430 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046671947.1 O77430 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046671947.1 O77430 R-DME-212436 Generic Transcription Pathway XP_046671947.1 O77430 R-DME-2262752 Cellular responses to stress XP_046671947.1 O77430 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046671947.1 O77430 R-DME-2565942 Regulation of PLK1 Activity at G2/M Transition XP_046671947.1 O77430 R-DME-2871837 FCERI mediated NF-kB activation XP_046671947.1 O77430 R-DME-382551 Transport of small molecules XP_046671947.1 O77430 R-DME-392499 Metabolism of proteins XP_046671947.1 O77430 R-DME-446652 Interleukin-1 family signaling XP_046671947.1 O77430 R-DME-449147 Signaling by Interleukins XP_046671947.1 O77430 R-DME-453274 Mitotic G2-G2/M phases XP_046671947.1 O77430 R-DME-453276 Regulation of mitotic cell cycle XP_046671947.1 O77430 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046671947.1 O77430 R-DME-5252538 Drosophila signaling pathways XP_046671947.1 O77430 R-DME-5358351 Signaling by Hedgehog XP_046671947.1 O77430 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046671947.1 O77430 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046671947.1 O77430 R-DME-5610780 Degradation of GLI1 by the proteasome XP_046671947.1 O77430 R-DME-5610785 GLI3 is processed to GLI3R by the proteasome XP_046671947.1 O77430 R-DME-5610787 Hedgehog 'off' state XP_046671947.1 O77430 R-DME-5621481 C-type lectin receptors (CLRs) XP_046671947.1 O77430 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046671947.1 O77430 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046671947.1 O77430 R-DME-597592 Post-translational protein modification XP_046671947.1 O77430 R-DME-68949 Orc1 removal from chromatin XP_046671947.1 O77430 R-DME-69052 Switching of origins to a post-replicative state XP_046671947.1 O77430 R-DME-69202 Cyclin E associated events during G1/S transition XP_046671947.1 O77430 R-DME-69206 G1/S Transition XP_046671947.1 O77430 R-DME-69231 Cyclin D associated events in G1 XP_046671947.1 O77430 R-DME-69236 G1 Phase XP_046671947.1 O77430 R-DME-69239 Synthesis of DNA XP_046671947.1 O77430 R-DME-69242 S Phase XP_046671947.1 O77430 R-DME-69275 G2/M Transition XP_046671947.1 O77430 R-DME-69278 Cell Cycle, Mitotic XP_046671947.1 O77430 R-DME-69306 DNA Replication XP_046671947.1 O77430 R-DME-69601 Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A XP_046671947.1 O77430 R-DME-69613 p53-Independent G1/S DNA Damage Checkpoint XP_046671947.1 O77430 R-DME-69615 G1/S DNA Damage Checkpoints XP_046671947.1 O77430 R-DME-69620 Cell Cycle Checkpoints XP_046671947.1 O77430 R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry XP_046671947.1 O77430 R-DME-73857 RNA Polymerase II Transcription XP_046671947.1 O77430 R-DME-74160 Gene expression (Transcription) XP_046671947.1 O77430 R-DME-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis XP_046671947.1 O77430 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046671947.1 O77430 R-DME-8939902 Regulation of RUNX2 expression and activity XP_046671947.1 O77430 R-DME-8951664 Neddylation XP_046671947.1 O77430 R-DME-8953897 Cellular responses to stimuli XP_046671947.1 O77430 R-DME-9020702 Interleukin-1 signaling XP_046671947.1 O77430 R-DME-917937 Iron uptake and transport XP_046671947.1 O77430 R-DME-9711123 Cellular response to chemical stress XP_046671947.1 O77430 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046671947.1 O77430 R-DME-9759194 Nuclear events mediated by NFE2L2 XP_046671947.1 O77430 R-DME-9762114 GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 XP_046671947.1 O77430 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046671947.1 O77430 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046671947.1 O77430 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046680829.1 Q2PDT4 R-DME-1500931 Cell-Cell communication XP_046680829.1 Q2PDT4 R-DME-162582 Signal Transduction XP_046680829.1 Q2PDT4 R-DME-397014 Muscle contraction XP_046680829.1 Q2PDT4 R-DME-445355 Smooth Muscle Contraction XP_046680829.1 Q2PDT4 R-DME-446343 Localization of the PINCH-ILK-PARVIN complex to focal adhesions XP_046680829.1 Q2PDT4 R-DME-446353 Cell-extracellular matrix interactions XP_046680829.1 Q2PDT4 R-DME-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components XP_046680829.1 Q2PDT4 R-DME-446728 Cell junction organization XP_046680829.1 Q2PDT4 R-DME-8848021 Signaling by PTK6 XP_046680829.1 Q2PDT4 R-DME-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases XP_046680829.1 Q2PDT4 R-DME-9006927 Signaling by Non-Receptor Tyrosine Kinases XP_046679556.1 O96299 R-DME-1430728 Metabolism XP_046679556.1 O96299 R-DME-5652084 Fructose metabolism XP_046679556.1 O96299 R-DME-5652227 Fructose biosynthesis XP_046679556.1 O96299 R-DME-5661270 Formation of xylulose-5-phosphate XP_046679556.1 O96299 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046673334.1 Q8SXX1 R-DME-1257604 PIP3 activates AKT signaling XP_046673334.1 Q8SXX1 R-DME-1430728 Metabolism XP_046673334.1 Q8SXX1 R-DME-1483255 PI Metabolism XP_046673334.1 Q8SXX1 R-DME-1483257 Phospholipid metabolism XP_046673334.1 Q8SXX1 R-DME-162582 Signal Transduction XP_046673334.1 Q8SXX1 R-DME-1660499 Synthesis of PIPs at the plasma membrane XP_046673334.1 Q8SXX1 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046673334.1 Q8SXX1 R-DME-212436 Generic Transcription Pathway XP_046673334.1 Q8SXX1 R-DME-3700989 Transcriptional Regulation by TP53 XP_046673334.1 Q8SXX1 R-DME-556833 Metabolism of lipids XP_046673334.1 Q8SXX1 R-DME-5633007 Regulation of TP53 Activity XP_046673334.1 Q8SXX1 R-DME-6804758 Regulation of TP53 Activity through Acetylation XP_046673334.1 Q8SXX1 R-DME-6811555 PI5P Regulates TP53 Acetylation XP_046673334.1 Q8SXX1 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046673334.1 Q8SXX1 R-DME-73857 RNA Polymerase II Transcription XP_046673334.1 Q8SXX1 R-DME-74160 Gene expression (Transcription) XP_046673334.1 Q8SXX1 R-DME-8847453 Synthesis of PIPs in the nucleus XP_046673334.1 Q8SXX1 R-DME-9006925 Intracellular signaling by second messengers YP_214939.1 P03896 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214939.1 P03896 R-DME-1430728 Metabolism YP_214939.1 P03896 R-DME-392499 Metabolism of proteins YP_214939.1 P03896 R-DME-5368287 Mitochondrial translation YP_214939.1 P03896 R-DME-5419276 Mitochondrial translation termination YP_214939.1 P03896 R-DME-611105 Respiratory electron transport YP_214939.1 P03896 R-DME-6799198 Complex I biogenesis YP_214939.1 P03896 R-DME-72766 Translation YP_214927.1 P00399 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214927.1 P00399 R-DME-1430728 Metabolism YP_214927.1 P00399 R-DME-212436 Generic Transcription Pathway YP_214927.1 P00399 R-DME-2262752 Cellular responses to stress YP_214927.1 P00399 R-DME-3700989 Transcriptional Regulation by TP53 YP_214927.1 P00399 R-DME-392499 Metabolism of proteins YP_214927.1 P00399 R-DME-5368287 Mitochondrial translation YP_214927.1 P00399 R-DME-5419276 Mitochondrial translation termination YP_214927.1 P00399 R-DME-5628897 TP53 Regulates Metabolic Genes YP_214927.1 P00399 R-DME-611105 Respiratory electron transport YP_214927.1 P00399 R-DME-72766 Translation YP_214927.1 P00399 R-DME-73857 RNA Polymerase II Transcription YP_214927.1 P00399 R-DME-74160 Gene expression (Transcription) YP_214927.1 P00399 R-DME-8953897 Cellular responses to stimuli YP_214927.1 P00399 R-DME-9707564 Cytoprotection by HMOX1 YP_214927.1 P00399 R-DME-9711123 Cellular response to chemical stress YP_214927.1 P00399 R-DME-9837999 Mitochondrial protein degradation YP_214927.1 P00399 R-DME-9864848 Complex IV assembly YP_214928.1 P00408 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214928.1 P00408 R-DME-1430728 Metabolism YP_214928.1 P00408 R-DME-212436 Generic Transcription Pathway YP_214928.1 P00408 R-DME-2262752 Cellular responses to stress YP_214928.1 P00408 R-DME-3700989 Transcriptional Regulation by TP53 YP_214928.1 P00408 R-DME-392499 Metabolism of proteins YP_214928.1 P00408 R-DME-5368287 Mitochondrial translation YP_214928.1 P00408 R-DME-5419276 Mitochondrial translation termination YP_214928.1 P00408 R-DME-5628897 TP53 Regulates Metabolic Genes YP_214928.1 P00408 R-DME-611105 Respiratory electron transport YP_214928.1 P00408 R-DME-72766 Translation YP_214928.1 P00408 R-DME-73857 RNA Polymerase II Transcription YP_214928.1 P00408 R-DME-74160 Gene expression (Transcription) YP_214928.1 P00408 R-DME-8953897 Cellular responses to stimuli YP_214928.1 P00408 R-DME-9707564 Cytoprotection by HMOX1 YP_214928.1 P00408 R-DME-9711123 Cellular response to chemical stress YP_214928.1 P00408 R-DME-9864848 Complex IV assembly YP_214930.1 P00850 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214930.1 P00850 R-DME-1430728 Metabolism YP_214930.1 P00850 R-DME-1592230 Mitochondrial biogenesis YP_214930.1 P00850 R-DME-163210 Formation of ATP by chemiosmotic coupling YP_214930.1 P00850 R-DME-1852241 Organelle biogenesis and maintenance YP_214930.1 P00850 R-DME-392499 Metabolism of proteins YP_214930.1 P00850 R-DME-5368287 Mitochondrial translation YP_214930.1 P00850 R-DME-5419276 Mitochondrial translation termination YP_214930.1 P00850 R-DME-72766 Translation YP_214930.1 P00850 R-DME-8949613 Cristae formation YP_214930.1 P00850 R-DME-9837999 Mitochondrial protein degradation YP_214931.1 P00417 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214931.1 P00417 R-DME-1430728 Metabolism YP_214931.1 P00417 R-DME-212436 Generic Transcription Pathway YP_214931.1 P00417 R-DME-2262752 Cellular responses to stress YP_214931.1 P00417 R-DME-3700989 Transcriptional Regulation by TP53 YP_214931.1 P00417 R-DME-392499 Metabolism of proteins YP_214931.1 P00417 R-DME-5368287 Mitochondrial translation YP_214931.1 P00417 R-DME-5419276 Mitochondrial translation termination YP_214931.1 P00417 R-DME-5628897 TP53 Regulates Metabolic Genes YP_214931.1 P00417 R-DME-611105 Respiratory electron transport YP_214931.1 P00417 R-DME-72766 Translation YP_214931.1 P00417 R-DME-73857 RNA Polymerase II Transcription YP_214931.1 P00417 R-DME-74160 Gene expression (Transcription) YP_214931.1 P00417 R-DME-8953897 Cellular responses to stimuli YP_214931.1 P00417 R-DME-9707564 Cytoprotection by HMOX1 YP_214931.1 P00417 R-DME-9711123 Cellular response to chemical stress YP_214931.1 P00417 R-DME-9864848 Complex IV assembly YP_214932.1 P18930 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214932.1 P18930 R-DME-1430728 Metabolism YP_214932.1 P18930 R-DME-392499 Metabolism of proteins YP_214932.1 P18930 R-DME-5368287 Mitochondrial translation YP_214932.1 P18930 R-DME-5419276 Mitochondrial translation termination YP_214932.1 P18930 R-DME-611105 Respiratory electron transport YP_214932.1 P18930 R-DME-6799198 Complex I biogenesis YP_214932.1 P18930 R-DME-72766 Translation XP_046675654.1 P18932 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046675654.1 P18932 R-DME-1430728 Metabolism XP_046675654.1 P18932 R-DME-392499 Metabolism of proteins XP_046675654.1 P18932 R-DME-5368287 Mitochondrial translation XP_046675654.1 P18932 R-DME-5419276 Mitochondrial translation termination XP_046675654.1 P18932 R-DME-611105 Respiratory electron transport XP_046675654.1 P18932 R-DME-6799198 Complex I biogenesis XP_046675654.1 P18932 R-DME-72766 Translation YP_214935.1 P18934 R-DME-392499 Metabolism of proteins YP_214935.1 P18934 R-DME-5368287 Mitochondrial translation YP_214935.1 P18934 R-DME-5419276 Mitochondrial translation termination YP_214935.1 P18934 R-DME-72766 Translation XP_046688134.1 P18933 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046688134.1 P18933 R-DME-1430728 Metabolism XP_046688134.1 P18933 R-DME-392499 Metabolism of proteins XP_046688134.1 P18933 R-DME-5368287 Mitochondrial translation XP_046688134.1 P18933 R-DME-5419276 Mitochondrial translation termination XP_046688134.1 P18933 R-DME-611105 Respiratory electron transport XP_046688134.1 P18933 R-DME-6799198 Complex I biogenesis XP_046688134.1 P18933 R-DME-72766 Translation YP_214937.1 P18935 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214937.1 P18935 R-DME-1430728 Metabolism YP_214937.1 P18935 R-DME-392499 Metabolism of proteins YP_214937.1 P18935 R-DME-5368287 Mitochondrial translation YP_214937.1 P18935 R-DME-5419276 Mitochondrial translation termination YP_214937.1 P18935 R-DME-611105 Respiratory electron transport YP_214937.1 P18935 R-DME-72766 Translation YP_214937.1 P18935 R-DME-9865881 Complex III assembly YP_214938.1 P18929 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214938.1 P18929 R-DME-1430728 Metabolism YP_214938.1 P18929 R-DME-392499 Metabolism of proteins YP_214938.1 P18929 R-DME-5368287 Mitochondrial translation YP_214938.1 P18929 R-DME-5419276 Mitochondrial translation termination YP_214938.1 P18929 R-DME-611105 Respiratory electron transport YP_214938.1 P18929 R-DME-6799198 Complex I biogenesis YP_214938.1 P18929 R-DME-72766 Translation XP_046667513.1 Q7PL91 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046667513.1 Q7PL91 R-DME-1430728 Metabolism XP_046667513.1 Q7PL91 R-DME-611105 Respiratory electron transport XP_046667513.1 Q7PL91 R-DME-6799198 Complex I biogenesis XP_046680119.1 P40417 R-DME-109581 Apoptosis XP_046680119.1 P40417 R-DME-109606 Intrinsic Pathway for Apoptosis XP_046680119.1 P40417 R-DME-110056 MAPK3 (ERK1) activation XP_046680119.1 P40417 R-DME-111458 Formation of apoptosome XP_046680119.1 P40417 R-DME-111461 Cytochrome c-mediated apoptotic response XP_046680119.1 P40417 R-DME-111471 Apoptotic factor-mediated response XP_046680119.1 P40417 R-DME-112409 RAF-independent MAPK1/3 activation XP_046680119.1 P40417 R-DME-112411 MAPK1 (ERK2) activation XP_046680119.1 P40417 R-DME-1181150 Signaling by NODAL XP_046680119.1 P40417 R-DME-1266738 Developmental Biology XP_046680119.1 P40417 R-DME-1280215 Cytokine Signaling in Immune system XP_046680119.1 P40417 R-DME-1295596 Spry regulation of FGF signaling XP_046680119.1 P40417 R-DME-1502540 Signaling by Activin XP_046680119.1 P40417 R-DME-162582 Signal Transduction XP_046680119.1 P40417 R-DME-162658 Golgi Cisternae Pericentriolar Stack Reorganization XP_046680119.1 P40417 R-DME-1640170 Cell Cycle XP_046680119.1 P40417 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046680119.1 P40417 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046680119.1 P40417 R-DME-166166 MyD88-independent TLR4 cascade XP_046680119.1 P40417 R-DME-166520 Signaling by NTRKs XP_046680119.1 P40417 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046680119.1 P40417 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046680119.1 P40417 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046680119.1 P40417 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046680119.1 P40417 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046680119.1 P40417 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046680119.1 P40417 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046680119.1 P40417 R-DME-168249 Innate Immune System XP_046680119.1 P40417 R-DME-168256 Immune System XP_046680119.1 P40417 R-DME-168898 Toll-like Receptor Cascades XP_046680119.1 P40417 R-DME-169893 Prolonged ERK activation events XP_046680119.1 P40417 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046680119.1 P40417 R-DME-170968 Frs2-mediated activation XP_046680119.1 P40417 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046680119.1 P40417 R-DME-187037 Signaling by NTRK1 (TRKA) XP_046680119.1 P40417 R-DME-187687 Signalling to ERKs XP_046680119.1 P40417 R-DME-190236 Signaling by FGFR XP_046680119.1 P40417 R-DME-194315 Signaling by Rho GTPases XP_046680119.1 P40417 R-DME-195258 RHO GTPase Effectors XP_046680119.1 P40417 R-DME-198725 Nuclear Events (kinase and transcription factor activation) XP_046680119.1 P40417 R-DME-198753 ERK/MAPK targets XP_046680119.1 P40417 R-DME-202670 ERKs are inactivated XP_046680119.1 P40417 R-DME-2029480 Fcgamma receptor (FCGR) dependent phagocytosis XP_046680119.1 P40417 R-DME-2029482 Regulation of actin dynamics for phagocytic cup formation XP_046680119.1 P40417 R-DME-212436 Generic Transcription Pathway XP_046680119.1 P40417 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046680119.1 P40417 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046680119.1 P40417 R-DME-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription XP_046680119.1 P40417 R-DME-2262752 Cellular responses to stress XP_046680119.1 P40417 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046680119.1 P40417 R-DME-2559580 Oxidative Stress Induced Senescence XP_046680119.1 P40417 R-DME-2559582 Senescence-Associated Secretory Phenotype (SASP) XP_046680119.1 P40417 R-DME-2559583 Cellular Senescence XP_046680119.1 P40417 R-DME-2559585 Oncogene Induced Senescence XP_046680119.1 P40417 R-DME-2871796 FCERI mediated MAPK activation XP_046680119.1 P40417 R-DME-3371453 Regulation of HSF1-mediated heat shock response XP_046680119.1 P40417 R-DME-3371556 Cellular response to heat stress XP_046680119.1 P40417 R-DME-372790 Signaling by GPCR XP_046680119.1 P40417 R-DME-373760 L1CAM interactions XP_046680119.1 P40417 R-DME-375165 NCAM signaling for neurite out-growth XP_046680119.1 P40417 R-DME-388396 GPCR downstream signalling XP_046680119.1 P40417 R-DME-416476 G alpha (q) signalling events XP_046680119.1 P40417 R-DME-422475 Axon guidance XP_046680119.1 P40417 R-DME-437239 Recycling pathway of L1 XP_046680119.1 P40417 R-DME-445144 Signal transduction by L1 XP_046680119.1 P40417 R-DME-448424 Interleukin-17 signaling XP_046680119.1 P40417 R-DME-449147 Signaling by Interleukins XP_046680119.1 P40417 R-DME-450282 MAPK targets/ Nuclear events mediated by MAP kinases XP_046680119.1 P40417 R-DME-450294 MAP kinase activation XP_046680119.1 P40417 R-DME-450341 Activation of the AP-1 family of transcription factors XP_046680119.1 P40417 R-DME-5357801 Programmed Cell Death XP_046680119.1 P40417 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046680119.1 P40417 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046680119.1 P40417 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046680119.1 P40417 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046680119.1 P40417 R-DME-5654736 Signaling by FGFR1 XP_046680119.1 P40417 R-DME-5654738 Signaling by FGFR2 XP_046680119.1 P40417 R-DME-5654741 Signaling by FGFR3 XP_046680119.1 P40417 R-DME-5654743 Signaling by FGFR4 XP_046680119.1 P40417 R-DME-5663213 RHO GTPases Activate WASPs and WAVEs XP_046680119.1 P40417 R-DME-5673001 RAF/MAP kinase cascade XP_046680119.1 P40417 R-DME-5674135 MAP2K and MAPK activation XP_046680119.1 P40417 R-DME-5674499 Negative feedback regulation of MAPK pathway XP_046680119.1 P40417 R-DME-5675221 Negative regulation of MAPK pathway XP_046680119.1 P40417 R-DME-5683057 MAPK family signaling cascades XP_046680119.1 P40417 R-DME-5684996 MAPK1/MAPK3 signaling XP_046680119.1 P40417 R-DME-6798695 Neutrophil degranulation XP_046680119.1 P40417 R-DME-68875 Mitotic Prophase XP_046680119.1 P40417 R-DME-68886 M Phase XP_046680119.1 P40417 R-DME-69278 Cell Cycle, Mitotic XP_046680119.1 P40417 R-DME-73857 RNA Polymerase II Transcription XP_046680119.1 P40417 R-DME-74160 Gene expression (Transcription) XP_046680119.1 P40417 R-DME-74749 Signal attenuation XP_046680119.1 P40417 R-DME-74751 Insulin receptor signalling cascade XP_046680119.1 P40417 R-DME-74752 Signaling by Insulin receptor XP_046680119.1 P40417 R-DME-877300 Interferon gamma signaling XP_046680119.1 P40417 R-DME-881907 Gastrin-CREB signalling pathway via PKC and MAPK XP_046680119.1 P40417 R-DME-8939211 ESR-mediated signaling XP_046680119.1 P40417 R-DME-8953897 Cellular responses to stimuli XP_046680119.1 P40417 R-DME-9006931 Signaling by Nuclear Receptors XP_046680119.1 P40417 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046680119.1 P40417 R-DME-9006936 Signaling by TGFB family members XP_046680119.1 P40417 R-DME-9009391 Extra-nuclear estrogen signaling XP_046680119.1 P40417 R-DME-913531 Interferon Signaling XP_046680119.1 P40417 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046680119.1 P40417 R-DME-9627069 Regulation of the apoptosome activity XP_046680119.1 P40417 R-DME-9634635 Estrogen-stimulated signaling through PRKCZ XP_046680119.1 P40417 R-DME-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling XP_046680119.1 P40417 R-DME-9675108 Nervous system development XP_046680119.1 P40417 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046680119.1 P40417 R-DME-9730414 MITF-M-regulated melanocyte development XP_046680119.1 P40417 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046680119.1 P40417 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046680119.1 P40417 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046680119.1 P40417 R-DME-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity XP_046681652.1 P35875 R-DME-5696394 DNA Damage Recognition in GG-NER XP_046681652.1 P35875 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046681652.1 P35875 R-DME-5696398 Nucleotide Excision Repair XP_046681652.1 P35875 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046681652.1 P35875 R-DME-5696400 Dual Incision in GG-NER XP_046681652.1 P35875 R-DME-73894 DNA Repair XP_046668688.1 P91943 R-DME-209412 Wingless pathway XP_046668688.1 P91943 R-DME-209421 Transcription activation by ARM XP_046668688.1 P91943 R-DME-209441 WG ligand not bound to FZ receptors XP_046668688.1 P91943 R-DME-209469 WG ligand bound to FZ receptors XP_046668688.1 P91943 R-DME-5252538 Drosophila signaling pathways XP_046668688.1 Q8IMA8 R-DME-1266738 Developmental Biology XP_046668688.1 Q8IMA8 R-DME-162582 Signal Transduction XP_046668688.1 Q8IMA8 R-DME-195253 Degradation of beta-catenin by the destruction complex XP_046668688.1 Q8IMA8 R-DME-195721 Signaling by WNT XP_046668688.1 Q8IMA8 R-DME-201681 TCF dependent signaling in response to WNT XP_046668688.1 Q8IMA8 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046668688.1 Q8IMA8 R-DME-212436 Generic Transcription Pathway XP_046668688.1 Q8IMA8 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046668688.1 Q8IMA8 R-DME-3858494 Beta-catenin independent WNT signaling XP_046668688.1 Q8IMA8 R-DME-4086398 Ca2+ pathway XP_046668688.1 Q8IMA8 R-DME-4641265 Repression of WNT target genes XP_046668688.1 Q8IMA8 R-DME-73857 RNA Polymerase II Transcription XP_046668688.1 Q8IMA8 R-DME-74160 Gene expression (Transcription) XP_046668688.1 Q8IMA8 R-DME-8853884 Transcriptional Regulation by VENTX XP_046668688.1 Q8IMA8 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046668688.1 Q8IMA8 R-DME-8951430 RUNX3 regulates WNT signaling XP_046668688.1 Q8IMA8 R-DME-9730414 MITF-M-regulated melanocyte development XP_046668688.1 Q8IMA8 R-DME-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation XP_046668688.1 Q8IMA8 R-DME-9856651 MITF-M-dependent gene expression XP_046689156.1 Q9VWP5 R-DME-3214815 HDACs deacetylate histones XP_046689156.1 Q9VWP5 R-DME-3247509 Chromatin modifying enzymes XP_046689156.1 Q9VWP5 R-DME-4839726 Chromatin organization XP_046673768.1 A8DYC4 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046673768.1 A8DYC4 R-DME-1430728 Metabolism XP_046673768.1 A8DYC4 R-DME-611105 Respiratory electron transport XP_046673768.1 A8DYC4 R-DME-6799198 Complex I biogenesis XP_046689164.1 M9PF61 R-DME-1430728 Metabolism XP_046689164.1 M9PF61 R-DME-162582 Signal Transduction XP_046689164.1 M9PF61 R-DME-192105 Synthesis of bile acids and bile salts XP_046689164.1 M9PF61 R-DME-193144 Estrogen biosynthesis XP_046689164.1 M9PF61 R-DME-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol XP_046689164.1 M9PF61 R-DME-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol XP_046689164.1 M9PF61 R-DME-193807 Synthesis of bile acids and bile salts via 27-hydroxycholesterol XP_046689164.1 M9PF61 R-DME-194068 Bile acid and bile salt metabolism XP_046689164.1 M9PF61 R-DME-196071 Metabolism of steroid hormones XP_046689164.1 M9PF61 R-DME-196108 Pregnenolone biosynthesis XP_046689164.1 M9PF61 R-DME-196854 Metabolism of vitamins and cofactors XP_046689164.1 M9PF61 R-DME-2142753 Arachidonate metabolism XP_046689164.1 M9PF61 R-DME-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) XP_046689164.1 M9PF61 R-DME-2187338 Visual phototransduction XP_046689164.1 M9PF61 R-DME-5362517 Signaling by Retinoic Acid XP_046689164.1 M9PF61 R-DME-5365859 RA biosynthesis pathway XP_046689164.1 M9PF61 R-DME-556833 Metabolism of lipids XP_046689164.1 M9PF61 R-DME-5652084 Fructose metabolism XP_046689164.1 M9PF61 R-DME-5652227 Fructose biosynthesis XP_046689164.1 M9PF61 R-DME-6806667 Metabolism of fat-soluble vitamins XP_046689164.1 M9PF61 R-DME-70221 Glycogen breakdown (glycogenolysis) XP_046689164.1 M9PF61 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046689164.1 M9PF61 R-DME-8957322 Metabolism of steroids XP_046689164.1 M9PF61 R-DME-8978868 Fatty acid metabolism XP_046689164.1 M9PF61 R-DME-8982491 Glycogen metabolism XP_046689164.1 M9PF61 R-DME-9006931 Signaling by Nuclear Receptors XP_046689164.1 M9PF61 R-DME-9709957 Sensory Perception XP_046689164.1 M9PF61 R-DME-9748784 Drug ADME XP_046689164.1 M9PF61 R-DME-975634 Retinoid metabolism and transport XP_046689164.1 M9PF61 R-DME-9757110 Prednisone ADME XP_046669523.1 P29613 R-DME-1430728 Metabolism XP_046669523.1 P29613 R-DME-70171 Glycolysis XP_046669523.1 P29613 R-DME-70263 Gluconeogenesis XP_046669523.1 P29613 R-DME-70326 Glucose metabolism XP_046669523.1 P29613 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046669444.1 A1Z9I5 R-DME-109582 Hemostasis XP_046669444.1 A1Z9I5 R-DME-162582 Signal Transduction XP_046669444.1 A1Z9I5 R-DME-194315 Signaling by Rho GTPases XP_046669444.1 A1Z9I5 R-DME-8980692 RHOA GTPase cycle XP_046669444.1 A1Z9I5 R-DME-9012999 RHO GTPase cycle XP_046669444.1 A1Z9I5 R-DME-9013148 CDC42 GTPase cycle XP_046669444.1 A1Z9I5 R-DME-9013149 RAC1 GTPase cycle XP_046669444.1 A1Z9I5 R-DME-9013423 RAC3 GTPase cycle XP_046669444.1 A1Z9I5 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046669444.1 A1Z9I5 R-DME-983189 Kinesins XP_046669444.1 A1Z9I5 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046674119.1 Q4TZQ4 R-DME-209447 Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY XP_046674119.1 Q4TZQ4 R-DME-209459 Imd pathway XP_046674119.1 Q4TZQ4 R-DME-5252538 Drosophila signaling pathways XP_046658985.1 Q961C5 R-DME-162582 Signal Transduction XP_046658985.1 Q961C5 R-DME-165159 MTOR signalling XP_046658985.1 Q961C5 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046658985.1 Q961C5 R-DME-212436 Generic Transcription Pathway XP_046658985.1 Q961C5 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046658985.1 Q961C5 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046658985.1 Q961C5 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046658985.1 Q961C5 R-DME-73857 RNA Polymerase II Transcription XP_046658985.1 Q961C5 R-DME-74160 Gene expression (Transcription) XP_046658985.1 Q961C5 R-DME-9006936 Signaling by TGFB family members XP_046662326.1 Q9W5D4 R-DME-392499 Metabolism of proteins XP_046662326.1 Q9W5D4 R-DME-5173105 O-linked glycosylation XP_046662326.1 Q9W5D4 R-DME-597592 Post-translational protein modification XP_046662326.1 Q9W5D4 R-DME-8931838 DAG1 glycosylations XP_046662326.1 Q9W5D4 R-DME-8932504 DAG1 core M2 glycosylations XP_046662326.1 Q9W5D4 R-DME-8932505 DAG1 core M3 glycosylations XP_046662326.1 Q9W5D4 R-DME-8932506 DAG1 core M1 glycosylations XP_046670281.1 Q24564 R-DME-162582 Signal Transduction XP_046670281.1 Q24564 R-DME-168249 Innate Immune System XP_046670281.1 Q24564 R-DME-168256 Immune System XP_046670281.1 Q24564 R-DME-194315 Signaling by Rho GTPases XP_046670281.1 Q24564 R-DME-195258 RHO GTPase Effectors XP_046670281.1 Q24564 R-DME-2029480 Fcgamma receptor (FCGR) dependent phagocytosis XP_046670281.1 Q24564 R-DME-2029482 Regulation of actin dynamics for phagocytic cup formation XP_046670281.1 Q24564 R-DME-5627123 RHO GTPases activate PAKs XP_046670281.1 Q24564 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046662070.1 Q9V3Y8 R-DME-1280215 Cytokine Signaling in Immune system XP_046662070.1 Q9V3Y8 R-DME-1632852 Macroautophagy XP_046662070.1 Q9V3Y8 R-DME-168249 Innate Immune System XP_046662070.1 Q9V3Y8 R-DME-168256 Immune System XP_046662070.1 Q9V3Y8 R-DME-1834941 STING mediated induction of host immune responses XP_046662070.1 Q9V3Y8 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046662070.1 Q9V3Y8 R-DME-3249367 STAT6-mediated induction of chemokines XP_046662070.1 Q9V3Y8 R-DME-446652 Interleukin-1 family signaling XP_046662070.1 Q9V3Y8 R-DME-449147 Signaling by Interleukins XP_046662070.1 Q9V3Y8 R-DME-5205647 Mitophagy XP_046662070.1 Q9V3Y8 R-DME-5205685 PINK1-PRKN Mediated Mitophagy XP_046662070.1 Q9V3Y8 R-DME-8953897 Cellular responses to stimuli XP_046662070.1 Q9V3Y8 R-DME-9008059 Interleukin-37 signaling XP_046662070.1 Q9V3Y8 R-DME-9612973 Autophagy XP_046662070.1 Q9V3Y8 R-DME-9663891 Selective autophagy XP_046662070.1 Q9V3Y8 R-DME-9855142 Cellular responses to mechanical stimuli XP_046662070.1 Q9V3Y8 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046662070.1 Q9V3Y8 R-DME-9860931 Response of endothelial cells to shear stress XP_046681191.1 Q9GQQ0 R-DME-1430728 Metabolism XP_046681191.1 Q9GQQ0 R-DME-1660661 Sphingolipid de novo biosynthesis XP_046681191.1 Q9GQQ0 R-DME-428157 Sphingolipid metabolism XP_046681191.1 Q9GQQ0 R-DME-556833 Metabolism of lipids XP_046670063.1 O46122 R-DME-209397 Formation of the cytosolic BSK 'scaffolding complex' XP_046670063.1 O46122 R-DME-209459 Imd pathway XP_046670063.1 O46122 R-DME-350431 Planar Cell Polarity pathway XP_046670063.1 O46122 R-DME-450724 JNK signalling XP_046670063.1 O46122 R-DME-450736 Activation of Downstream Effectors XP_046670063.1 O46122 R-DME-5252538 Drosophila signaling pathways XP_046670063.1 Q9VHV8 R-DME-112409 RAF-independent MAPK1/3 activation XP_046670063.1 Q9VHV8 R-DME-162582 Signal Transduction XP_046670063.1 Q9VHV8 R-DME-5673001 RAF/MAP kinase cascade XP_046670063.1 Q9VHV8 R-DME-5675221 Negative regulation of MAPK pathway XP_046670063.1 Q9VHV8 R-DME-5683057 MAPK family signaling cascades XP_046670063.1 Q9VHV8 R-DME-5684996 MAPK1/MAPK3 signaling XP_046659756.1 Q9VV75 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046659756.1 Q9VV75 R-DME-1430728 Metabolism XP_046659756.1 Q9VV75 R-DME-392499 Metabolism of proteins XP_046659756.1 Q9VV75 R-DME-611105 Respiratory electron transport XP_046659756.1 Q9VV75 R-DME-9837999 Mitochondrial protein degradation XP_046659756.1 Q9VV75 R-DME-9865881 Complex III assembly XP_046677957.1 Q86BR9 R-DME-209387 Phosphorylation of ARR XP_046677957.1 Q86BR9 R-DME-209412 Wingless pathway XP_046677957.1 Q86BR9 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046677957.1 Q86BR9 R-DME-209469 WG ligand bound to FZ receptors XP_046677957.1 Q86BR9 R-DME-209472 Assembly of receptor complex XP_046677957.1 Q86BR9 R-DME-5252538 Drosophila signaling pathways XP_046677957.1 A0A0B4KHL4 R-DME-1430728 Metabolism XP_046677957.1 A0A0B4KHL4 R-DME-1660661 Sphingolipid de novo biosynthesis XP_046677957.1 A0A0B4KHL4 R-DME-428157 Sphingolipid metabolism XP_046677957.1 A0A0B4KHL4 R-DME-556833 Metabolism of lipids XP_046683140.1 Q01604 R-DME-1430728 Metabolism XP_046683140.1 Q01604 R-DME-162582 Signal Transduction XP_046683140.1 Q01604 R-DME-165159 MTOR signalling XP_046683140.1 Q01604 R-DME-70171 Glycolysis XP_046683140.1 Q01604 R-DME-70263 Gluconeogenesis XP_046683140.1 Q01604 R-DME-70326 Glucose metabolism XP_046683140.1 Q01604 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046665096.1 P49657 R-DME-1538133 G0 and Early G1 XP_046665096.1 P49657 R-DME-1640170 Cell Cycle XP_046665096.1 P49657 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046665096.1 P49657 R-DME-69278 Cell Cycle, Mitotic XP_046668814.1 P53624 R-DME-392499 Metabolism of proteins XP_046668814.1 P53624 R-DME-446203 Asparagine N-linked glycosylation XP_046668814.1 P53624 R-DME-597592 Post-translational protein modification XP_046668814.1 P53624 R-DME-948021 Transport to the Golgi and subsequent modification XP_046668814.1 P53624 R-DME-964739 N-glycan trimming and elongation in the cis-Golgi XP_046668814.1 P53624 R-DME-964827 Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 XP_046662601.1 Q9VVI3 R-DME-1236394 Signaling by ERBB4 XP_046662601.1 Q9VVI3 R-DME-1253288 Downregulation of ERBB4 signaling XP_046662601.1 Q9VVI3 R-DME-1257604 PIP3 activates AKT signaling XP_046662601.1 Q9VVI3 R-DME-1280218 Adaptive Immune System XP_046662601.1 Q9VVI3 R-DME-162582 Signal Transduction XP_046662601.1 Q9VVI3 R-DME-168256 Immune System XP_046662601.1 Q9VVI3 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046662601.1 Q9VVI3 R-DME-212436 Generic Transcription Pathway XP_046662601.1 Q9VVI3 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046662601.1 Q9VVI3 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046662601.1 Q9VVI3 R-DME-6807070 PTEN Regulation XP_046662601.1 Q9VVI3 R-DME-73857 RNA Polymerase II Transcription XP_046662601.1 Q9VVI3 R-DME-74160 Gene expression (Transcription) XP_046662601.1 Q9VVI3 R-DME-8948747 Regulation of PTEN localization XP_046662601.1 Q9VVI3 R-DME-8948751 Regulation of PTEN stability and activity XP_046662601.1 Q9VVI3 R-DME-9006925 Intracellular signaling by second messengers XP_046662601.1 Q9VVI3 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046662601.1 Q9VVI3 R-DME-9006936 Signaling by TGFB family members XP_046662601.1 Q9VVI3 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046662601.1 Q9VVI3 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046665475.1 Q9VN82 R-DME-1500931 Cell-Cell communication XP_046665475.1 Q9VN82 R-DME-418990 Adherens junctions interactions XP_046665475.1 Q9VN82 R-DME-421270 Cell-cell junction organization XP_046665475.1 Q9VN82 R-DME-446728 Cell junction organization XP_046670312.1 O77086 R-DME-1280215 Cytokine Signaling in Immune system XP_046670312.1 O77086 R-DME-162582 Signal Transduction XP_046670312.1 O77086 R-DME-168256 Immune System XP_046670312.1 O77086 R-DME-186763 Downstream signal transduction XP_046670312.1 O77086 R-DME-186797 Signaling by PDGF XP_046670312.1 O77086 R-DME-194315 Signaling by Rho GTPases XP_046670312.1 O77086 R-DME-449147 Signaling by Interleukins XP_046670312.1 O77086 R-DME-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling XP_046670312.1 O77086 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046670312.1 O77086 R-DME-9012999 RHO GTPase cycle XP_046670312.1 O77086 R-DME-9013423 RAC3 GTPase cycle XP_046670312.1 O77086 R-DME-912631 Regulation of signaling by CBL XP_046670312.1 O77086 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046662674.1 P16905 R-DME-109582 Hemostasis XP_046662674.1 P16905 R-DME-111885 Opioid Signalling XP_046662674.1 P16905 R-DME-111931 PKA-mediated phosphorylation of CREB XP_046662674.1 P16905 R-DME-111933 Calmodulin induced events XP_046662674.1 P16905 R-DME-111996 Ca-dependent events XP_046662674.1 P16905 R-DME-111997 CaM pathway XP_046662674.1 P16905 R-DME-112040 G-protein mediated events XP_046662674.1 P16905 R-DME-112043 PLC beta mediated events XP_046662674.1 P16905 R-DME-112314 Neurotransmitter receptors and postsynaptic signal transmission XP_046662674.1 P16905 R-DME-112315 Transmission across Chemical Synapses XP_046662674.1 P16905 R-DME-112316 Neuronal System XP_046662674.1 P16905 R-DME-1430728 Metabolism XP_046662674.1 P16905 R-DME-1489509 DAG and IP3 signaling XP_046662674.1 P16905 R-DME-162582 Signal Transduction XP_046662674.1 P16905 R-DME-163359 Glucagon signaling in metabolic regulation XP_046662674.1 P16905 R-DME-163615 PKA activation XP_046662674.1 P16905 R-DME-163685 Integration of energy metabolism XP_046662674.1 P16905 R-DME-164378 PKA activation in glucagon signalling XP_046662674.1 P16905 R-DME-180024 DARPP-32 events XP_046662674.1 P16905 R-DME-372790 Signaling by GPCR XP_046662674.1 P16905 R-DME-382551 Transport of small molecules XP_046662674.1 P16905 R-DME-388396 GPCR downstream signalling XP_046662674.1 P16905 R-DME-418555 G alpha (s) signalling events XP_046662674.1 P16905 R-DME-418594 G alpha (i) signalling events XP_046662674.1 P16905 R-DME-432040 Vasopressin regulates renal water homeostasis via Aquaporins XP_046662674.1 P16905 R-DME-438064 Post NMDA receptor activation events XP_046662674.1 P16905 R-DME-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase XP_046662674.1 P16905 R-DME-442755 Activation of NMDA receptors and postsynaptic events XP_046662674.1 P16905 R-DME-445717 Aquaporin-mediated transport XP_046662674.1 P16905 R-DME-5358351 Signaling by Hedgehog XP_046662674.1 P16905 R-DME-5610787 Hedgehog 'off' state XP_046662674.1 P16905 R-DME-8953897 Cellular responses to stimuli XP_046662674.1 P16905 R-DME-9006925 Intracellular signaling by second messengers XP_046662674.1 P16905 R-DME-9634597 GPER1 signaling XP_046662674.1 P16905 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046662674.1 P16905 R-DME-9855142 Cellular responses to mechanical stimuli XP_046662674.1 P16905 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046662674.1 P16905 R-DME-9860931 Response of endothelial cells to shear stress XP_046671224.1 P10040 R-DME-157118 Signaling by NOTCH XP_046671224.1 P10040 R-DME-162582 Signal Transduction XP_046671224.1 P10040 R-DME-1912420 Pre-NOTCH Processing in Golgi XP_046671224.1 P10040 R-DME-1912422 Pre-NOTCH Expression and Processing XP_046671224.1 P10040 R-DME-9013694 Signaling by NOTCH4 XP_046671224.1 P10040 R-DME-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus XP_046671224.1 P10040 R-DME-9604323 Negative regulation of NOTCH4 signaling XP_046670748.1 Q9Y0Z0 R-DME-392499 Metabolism of proteins XP_046670748.1 Q9Y0Z0 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046670748.1 Q9Y0Z0 R-DME-446203 Asparagine N-linked glycosylation XP_046670748.1 Q9Y0Z0 R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine XP_046670748.1 Q9Y0Z0 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046670748.1 Q9Y0Z0 R-DME-597592 Post-translational protein modification XP_046681968.1 A8Y535 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046681968.1 A8Y535 R-DME-1430728 Metabolism XP_046681968.1 A8Y535 R-DME-611105 Respiratory electron transport XP_046681968.1 A8Y535 R-DME-9865881 Complex III assembly XP_046663985.1 P15330 R-DME-1168372 Downstream signaling events of B Cell Receptor (BCR) XP_046663985.1 P15330 R-DME-1169091 Activation of NF-kappaB in B cells XP_046663985.1 P15330 R-DME-1280215 Cytokine Signaling in Immune system XP_046663985.1 P15330 R-DME-1280218 Adaptive Immune System XP_046663985.1 P15330 R-DME-1500931 Cell-Cell communication XP_046663985.1 P15330 R-DME-1606322 ZBP1(DAI) mediated induction of type I IFNs XP_046663985.1 P15330 R-DME-162582 Signal Transduction XP_046663985.1 P15330 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046663985.1 P15330 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046663985.1 P15330 R-DME-166166 MyD88-independent TLR4 cascade XP_046663985.1 P15330 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046663985.1 P15330 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046663985.1 P15330 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046663985.1 P15330 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046663985.1 P15330 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046663985.1 P15330 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046663985.1 P15330 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046663985.1 P15330 R-DME-168249 Innate Immune System XP_046663985.1 P15330 R-DME-168256 Immune System XP_046663985.1 P15330 R-DME-168898 Toll-like Receptor Cascades XP_046663985.1 P15330 R-DME-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta XP_046663985.1 P15330 R-DME-1810476 RIP-mediated NFkB activation via ZBP1 XP_046663985.1 P15330 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046663985.1 P15330 R-DME-1834949 Cytosolic sensors of pathogen-associated DNA XP_046663985.1 P15330 R-DME-193639 p75NTR signals via NF-kB XP_046663985.1 P15330 R-DME-193704 p75 NTR receptor-mediated signalling XP_046663985.1 P15330 R-DME-202403 TCR signaling XP_046663985.1 P15330 R-DME-202424 Downstream TCR signaling XP_046663985.1 P15330 R-DME-209400 Transcriptional activtion by phosphorylated DL/DIF dimer XP_046663985.1 P15330 R-DME-209406 Degradation of NF-kappa-B inhibitor, CACT XP_046663985.1 P15330 R-DME-209449 Toll pathway XP_046663985.1 P15330 R-DME-209560 NF-kB is activated and signals survival XP_046663985.1 P15330 R-DME-214842 DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' XP_046663985.1 P15330 R-DME-214844 DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' XP_046663985.1 P15330 R-DME-214869 Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex' XP_046663985.1 P15330 R-DME-2454202 Fc epsilon receptor (FCERI) signaling XP_046663985.1 P15330 R-DME-2871837 FCERI mediated NF-kB activation XP_046663985.1 P15330 R-DME-2990846 SUMOylation XP_046663985.1 P15330 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046663985.1 P15330 R-DME-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production XP_046663985.1 P15330 R-DME-392499 Metabolism of proteins XP_046663985.1 P15330 R-DME-418990 Adherens junctions interactions XP_046663985.1 P15330 R-DME-421270 Cell-cell junction organization XP_046663985.1 P15330 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046663985.1 P15330 R-DME-446652 Interleukin-1 family signaling XP_046663985.1 P15330 R-DME-446728 Cell junction organization XP_046663985.1 P15330 R-DME-449147 Signaling by Interleukins XP_046663985.1 P15330 R-DME-4755510 SUMOylation of immune response proteins XP_046663985.1 P15330 R-DME-5252538 Drosophila signaling pathways XP_046663985.1 P15330 R-DME-5607761 Dectin-1 mediated noncanonical NF-kB signaling XP_046663985.1 P15330 R-DME-5607764 CLEC7A (Dectin-1) signaling XP_046663985.1 P15330 R-DME-5621481 C-type lectin receptors (CLRs) XP_046663985.1 P15330 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046663985.1 P15330 R-DME-5668541 TNFR2 non-canonical NF-kB pathway XP_046663985.1 P15330 R-DME-5676590 NIK-->noncanonical NF-kB signaling XP_046663985.1 P15330 R-DME-597592 Post-translational protein modification XP_046663985.1 P15330 R-DME-73887 Death Receptor Signaling XP_046663985.1 P15330 R-DME-8953897 Cellular responses to stimuli XP_046663985.1 P15330 R-DME-9020702 Interleukin-1 signaling XP_046663985.1 P15330 R-DME-933542 TRAF6 mediated NF-kB activation XP_046663985.1 P15330 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046663985.1 P15330 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046663985.1 P15330 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046663985.1 P15330 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046663985.1 P15330 R-DME-983705 Signaling by the B Cell Receptor (BCR) XP_046663985.1 P15330 R-DME-9855142 Cellular responses to mechanical stimuli XP_046663985.1 P15330 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046663985.1 P15330 R-DME-9860931 Response of endothelial cells to shear stress XP_046663985.1 P15330 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046670434.1 Q24306 R-DME-109581 Apoptosis XP_046670434.1 Q24306 R-DME-109606 Intrinsic Pathway for Apoptosis XP_046670434.1 Q24306 R-DME-111458 Formation of apoptosome XP_046670434.1 Q24306 R-DME-111459 Activation of caspases through apoptosome-mediated cleavage XP_046670434.1 Q24306 R-DME-111461 Cytochrome c-mediated apoptotic response XP_046670434.1 Q24306 R-DME-111469 SMAC, XIAP-regulated apoptotic response XP_046670434.1 Q24306 R-DME-111471 Apoptotic factor-mediated response XP_046670434.1 Q24306 R-DME-1257604 PIP3 activates AKT signaling XP_046670434.1 Q24306 R-DME-1500931 Cell-Cell communication XP_046670434.1 Q24306 R-DME-162582 Signal Transduction XP_046670434.1 Q24306 R-DME-195721 Signaling by WNT XP_046670434.1 Q24306 R-DME-201681 TCF dependent signaling in response to WNT XP_046670434.1 Q24306 R-DME-3769402 Deactivation of the beta-catenin transactivating complex XP_046670434.1 Q24306 R-DME-390146 Hippo/Warts pathway XP_046670434.1 Q24306 R-DME-390150 DS ligand bound to FT receptor XP_046670434.1 Q24306 R-DME-418990 Adherens junctions interactions XP_046670434.1 Q24306 R-DME-421270 Cell-cell junction organization XP_046670434.1 Q24306 R-DME-446728 Cell junction organization XP_046670434.1 Q24306 R-DME-5213460 RIPK1-mediated regulated necrosis XP_046670434.1 Q24306 R-DME-5218859 Regulated Necrosis XP_046670434.1 Q24306 R-DME-5252538 Drosophila signaling pathways XP_046670434.1 Q24306 R-DME-5357801 Programmed Cell Death XP_046670434.1 Q24306 R-DME-5675482 Regulation of necroptotic cell death XP_046670434.1 Q24306 R-DME-6807070 PTEN Regulation XP_046670434.1 Q24306 R-DME-8948747 Regulation of PTEN localization XP_046670434.1 Q24306 R-DME-8948751 Regulation of PTEN stability and activity XP_046670434.1 Q24306 R-DME-9006925 Intracellular signaling by second messengers XP_046670434.1 Q24306 R-DME-9627069 Regulation of the apoptosome activity XP_046670434.1 Q24306 R-DME-9958825 Activation of STAT3 by cadherin engagement XP_046679993.1 P32865 R-DME-111885 Opioid Signalling XP_046679993.1 P32865 R-DME-111933 Calmodulin induced events XP_046679993.1 P32865 R-DME-111996 Ca-dependent events XP_046679993.1 P32865 R-DME-111997 CaM pathway XP_046679993.1 P32865 R-DME-112040 G-protein mediated events XP_046679993.1 P32865 R-DME-112043 PLC beta mediated events XP_046679993.1 P32865 R-DME-1489509 DAG and IP3 signaling XP_046679993.1 P32865 R-DME-162582 Signal Transduction XP_046679993.1 P32865 R-DME-372790 Signaling by GPCR XP_046679993.1 P32865 R-DME-388396 GPCR downstream signalling XP_046679993.1 P32865 R-DME-416476 G alpha (q) signalling events XP_046679993.1 P32865 R-DME-418555 G alpha (s) signalling events XP_046679993.1 P32865 R-DME-418594 G alpha (i) signalling events XP_046679993.1 P32865 R-DME-5358351 Signaling by Hedgehog XP_046679993.1 P32865 R-DME-5632684 Hedgehog 'on' state XP_046679993.1 P32865 R-DME-5635838 Activation of SMO XP_046679993.1 P32865 R-DME-9006925 Intracellular signaling by second messengers XP_046681059.1 A0A0B4KFY0 R-DME-1280218 Adaptive Immune System XP_046681059.1 A0A0B4KFY0 R-DME-168256 Immune System XP_046681059.1 A0A0B4KFY0 R-DME-174824 Plasma lipoprotein assembly, remodeling, and clearance XP_046681059.1 A0A0B4KFY0 R-DME-382551 Transport of small molecules XP_046681059.1 A0A0B4KFY0 R-DME-8866427 VLDLR internalisation and degradation XP_046681059.1 A0A0B4KFY0 R-DME-8964043 Plasma lipoprotein clearance XP_046681059.1 A0A0B4KFY0 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046681059.1 A0A0B4KFY0 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046676563.1 Q95U75 R-DME-209159 Assembly of the CI containing complexes XP_046676563.1 Q95U75 R-DME-209190 Phosphorylation of CI XP_046676563.1 Q95U75 R-DME-209214 Phosphorylation of SMO XP_046676563.1 Q95U75 R-DME-209392 Hedgehog pathway XP_046676563.1 Q95U75 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046676563.1 Q95U75 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046676563.1 Q95U75 R-DME-216217 Activation of SMO XP_046676563.1 Q95U75 R-DME-432553 Phosphorylation of PER and TIM XP_046676563.1 Q95U75 R-DME-432626 Circadian Clock pathway XP_046676563.1 Q95U75 R-DME-5252538 Drosophila signaling pathways XP_046676563.1 A1ZBL9 R-DME-1266738 Developmental Biology XP_046676563.1 A1ZBL9 R-DME-162582 Signal Transduction XP_046676563.1 A1ZBL9 R-DME-5673000 RAF activation XP_046676563.1 A1ZBL9 R-DME-5673001 RAF/MAP kinase cascade XP_046676563.1 A1ZBL9 R-DME-5674135 MAP2K and MAPK activation XP_046676563.1 A1ZBL9 R-DME-5675221 Negative regulation of MAPK pathway XP_046676563.1 A1ZBL9 R-DME-5683057 MAPK family signaling cascades XP_046676563.1 A1ZBL9 R-DME-5684996 MAPK1/MAPK3 signaling XP_046676563.1 A1ZBL9 R-DME-9730414 MITF-M-regulated melanocyte development XP_046676563.1 A1ZBL9 R-DME-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity XP_046660386.1 Q9VRP5 R-DME-162582 Signal Transduction XP_046660386.1 Q9VRP5 R-DME-392499 Metabolism of proteins XP_046660386.1 Q9VRP5 R-DME-5673001 RAF/MAP kinase cascade XP_046660386.1 Q9VRP5 R-DME-5683057 MAPK family signaling cascades XP_046660386.1 Q9VRP5 R-DME-5684996 MAPK1/MAPK3 signaling XP_046660386.1 Q9VRP5 R-DME-5688426 Deubiquitination XP_046660386.1 Q9VRP5 R-DME-5689880 Ub-specific processing proteases XP_046660386.1 Q9VRP5 R-DME-597592 Post-translational protein modification XP_046660386.1 Q9VRP5 R-DME-9648002 RAS processing XP_046673064.1 Q9VLQ1 R-DME-392499 Metabolism of proteins XP_046673064.1 Q9VLQ1 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046673064.1 Q9VLQ1 R-DME-446203 Asparagine N-linked glycosylation XP_046673064.1 Q9VLQ1 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046673064.1 Q9VLQ1 R-DME-480985 Synthesis of dolichyl-phosphate-glucose XP_046673064.1 Q9VLQ1 R-DME-597592 Post-translational protein modification XP_046676516.1 Q8IP45 R-DME-1280218 Adaptive Immune System XP_046676516.1 Q8IP45 R-DME-162582 Signal Transduction XP_046676516.1 Q8IP45 R-DME-168256 Immune System XP_046676516.1 Q8IP45 R-DME-194315 Signaling by Rho GTPases XP_046676516.1 Q8IP45 R-DME-195721 Signaling by WNT XP_046676516.1 Q8IP45 R-DME-201681 TCF dependent signaling in response to WNT XP_046676516.1 Q8IP45 R-DME-2262752 Cellular responses to stress XP_046676516.1 Q8IP45 R-DME-388841 Regulation of T cell activation by CD28 family XP_046676516.1 Q8IP45 R-DME-389948 Co-inhibition by PD-1 XP_046676516.1 Q8IP45 R-DME-392499 Metabolism of proteins XP_046676516.1 Q8IP45 R-DME-4641258 Degradation of DVL XP_046676516.1 Q8IP45 R-DME-5358351 Signaling by Hedgehog XP_046676516.1 Q8IP45 R-DME-5632684 Hedgehog 'on' state XP_046676516.1 Q8IP45 R-DME-597592 Post-translational protein modification XP_046676516.1 Q8IP45 R-DME-8951664 Neddylation XP_046676516.1 Q8IP45 R-DME-8953897 Cellular responses to stimuli XP_046676516.1 Q8IP45 R-DME-9012999 RHO GTPase cycle XP_046676516.1 Q8IP45 R-DME-9013418 RHOBTB2 GTPase cycle XP_046676516.1 Q8IP45 R-DME-9013422 RHOBTB1 GTPase cycle XP_046676516.1 Q8IP45 R-DME-9706574 RHOBTB GTPase Cycle XP_046676516.1 Q8IP45 R-DME-9711123 Cellular response to chemical stress XP_046676516.1 Q8IP45 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046676516.1 Q8IP45 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046676516.1 Q8IP45 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046676516.1 Q8IP45 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046676516.1 Q8IP45 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046676516.1 Q8IP45 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046676516.1 Q8IP45 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046676516.1 Q9V475 R-DME-209392 Hedgehog pathway XP_046676516.1 Q9V475 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046676516.1 Q9V475 R-DME-216167 Nuclear CI is degraded XP_046676516.1 Q9V475 R-DME-5252538 Drosophila signaling pathways XP_046679149.1 Q7KJA9 R-DME-212165 Epigenetic regulation of gene expression XP_046679149.1 Q7KJA9 R-DME-3214847 HATs acetylate histones XP_046679149.1 Q7KJA9 R-DME-3247509 Chromatin modifying enzymes XP_046679149.1 Q7KJA9 R-DME-392499 Metabolism of proteins XP_046679149.1 Q7KJA9 R-DME-4839726 Chromatin organization XP_046679149.1 Q7KJA9 R-DME-5688426 Deubiquitination XP_046679149.1 Q7KJA9 R-DME-5689603 UCH proteinases XP_046679149.1 Q7KJA9 R-DME-597592 Post-translational protein modification XP_046679149.1 Q7KJA9 R-DME-74160 Gene expression (Transcription) XP_046679149.1 Q7KJA9 R-DME-9772755 Formation of WDR5-containing histone-modifying complexes XP_046679149.1 Q7KJA9 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046672595.1 Q94523 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046672595.1 Q94523 R-DME-1430728 Metabolism XP_046672595.1 Q94523 R-DME-71403 Citric acid cycle (TCA cycle) XP_046672595.1 Q94523 R-DME-9854311 Maturation of TCA enzymes and regulation of TCA cycle XP_046667537.1 O02373 R-DME-1430728 Metabolism XP_046667537.1 O02373 R-DME-156580 Phase II - Conjugation of compounds XP_046667537.1 O02373 R-DME-156588 Glucuronidation XP_046667537.1 O02373 R-DME-173599 Formation of the active cofactor, UDP-glucuronate XP_046667537.1 O02373 R-DME-211859 Biological oxidations XP_046674421.1 Q8T0S6 R-DME-162582 Signal Transduction XP_046674421.1 Q8T0S6 R-DME-2028269 Signaling by Hippo XP_046674421.1 Q8T0S6 R-DME-390089 Formation of the Hippo kinase cassette XP_046674421.1 Q8T0S6 R-DME-390098 Phosphorylation-dependent inhibition of YKI XP_046674421.1 Q8T0S6 R-DME-390146 Hippo/Warts pathway XP_046674421.1 Q8T0S6 R-DME-390150 DS ligand bound to FT receptor XP_046674421.1 Q8T0S6 R-DME-451806 Phosphorylation-independent inhibition of YKI XP_046674421.1 Q8T0S6 R-DME-5252538 Drosophila signaling pathways XP_046660608.1 O62602 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046660608.1 O62602 R-DME-1280215 Cytokine Signaling in Immune system XP_046660608.1 O62602 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046660608.1 O62602 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046660608.1 O62602 R-DME-166166 MyD88-independent TLR4 cascade XP_046660608.1 O62602 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046660608.1 O62602 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046660608.1 O62602 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046660608.1 O62602 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046660608.1 O62602 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046660608.1 O62602 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046660608.1 O62602 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046660608.1 O62602 R-DME-168249 Innate Immune System XP_046660608.1 O62602 R-DME-168256 Immune System XP_046660608.1 O62602 R-DME-168638 NOD1/2 Signaling Pathway XP_046660608.1 O62602 R-DME-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways XP_046660608.1 O62602 R-DME-168898 Toll-like Receptor Cascades XP_046660608.1 O62602 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046660608.1 O62602 R-DME-212436 Generic Transcription Pathway XP_046660608.1 O62602 R-DME-2262752 Cellular responses to stress XP_046660608.1 O62602 R-DME-2559580 Oxidative Stress Induced Senescence XP_046660608.1 O62602 R-DME-2559583 Cellular Senescence XP_046660608.1 O62602 R-DME-3700989 Transcriptional Regulation by TP53 XP_046660608.1 O62602 R-DME-448424 Interleukin-17 signaling XP_046660608.1 O62602 R-DME-449147 Signaling by Interleukins XP_046660608.1 O62602 R-DME-450294 MAP kinase activation XP_046660608.1 O62602 R-DME-450302 activated TAK1 mediates p38 MAPK activation XP_046660608.1 O62602 R-DME-5633007 Regulation of TP53 Activity XP_046660608.1 O62602 R-DME-6804758 Regulation of TP53 Activity through Acetylation XP_046660608.1 O62602 R-DME-6811555 PI5P Regulates TP53 Acetylation XP_046660608.1 O62602 R-DME-73857 RNA Polymerase II Transcription XP_046660608.1 O62602 R-DME-74160 Gene expression (Transcription) XP_046660608.1 O62602 R-DME-8953897 Cellular responses to stimuli XP_046660608.1 O62602 R-DME-913531 Interferon Signaling XP_046660608.1 O62602 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046660608.1 O62602 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046660608.1 O62602 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046660608.1 O62602 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046660608.1 O62602 R-DME-9833482 PKR-mediated signaling XP_046672820.1 Q9XZ56 R-DME-110523 TOR signaling pathway XP_046672820.1 Q9XZ56 R-DME-110526 Insulin receptor mediated signaling XP_046672820.1 Q9XZ56 R-DME-162582 Signal Transduction XP_046672820.1 Q9XZ56 R-DME-165159 MTOR signalling XP_046672820.1 Q9XZ56 R-DME-166208 mTORC1-mediated signalling XP_046672820.1 Q9XZ56 R-DME-392499 Metabolism of proteins XP_046672820.1 Q9XZ56 R-DME-5252538 Drosophila signaling pathways XP_046672820.1 Q9XZ56 R-DME-72613 Eukaryotic Translation Initiation XP_046672820.1 Q9XZ56 R-DME-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S XP_046672820.1 Q9XZ56 R-DME-72737 Cap-dependent Translation Initiation XP_046672820.1 Q9XZ56 R-DME-72766 Translation XP_046670960.1 M9MS40 R-DME-1234158 Regulation of gene expression by Hypoxia-inducible Factor XP_046670960.1 M9MS40 R-DME-1234174 Cellular response to hypoxia XP_046670960.1 M9MS40 R-DME-1266738 Developmental Biology XP_046670960.1 M9MS40 R-DME-1430728 Metabolism XP_046670960.1 M9MS40 R-DME-162582 Signal Transduction XP_046670960.1 M9MS40 R-DME-168249 Innate Immune System XP_046670960.1 M9MS40 R-DME-168256 Immune System XP_046670960.1 M9MS40 R-DME-195721 Signaling by WNT XP_046670960.1 M9MS40 R-DME-201556 Signaling by ALK XP_046670960.1 M9MS40 R-DME-201681 TCF dependent signaling in response to WNT XP_046670960.1 M9MS40 R-DME-201722 Formation of the beta-catenin:TCF transactivating complex XP_046670960.1 M9MS40 R-DME-212165 Epigenetic regulation of gene expression XP_046670960.1 M9MS40 R-DME-212436 Generic Transcription Pathway XP_046670960.1 M9MS40 R-DME-2262752 Cellular responses to stress XP_046670960.1 M9MS40 R-DME-3214847 HATs acetylate histones XP_046670960.1 M9MS40 R-DME-3247509 Chromatin modifying enzymes XP_046670960.1 M9MS40 R-DME-3700989 Transcriptional Regulation by TP53 XP_046670960.1 M9MS40 R-DME-400206 Regulation of lipid metabolism by PPARalpha XP_046670960.1 M9MS40 R-DME-4839726 Chromatin organization XP_046670960.1 M9MS40 R-DME-556833 Metabolism of lipids XP_046670960.1 M9MS40 R-DME-5621481 C-type lectin receptors (CLRs) XP_046670960.1 M9MS40 R-DME-5621575 CD209 (DC-SIGN) signaling XP_046670960.1 M9MS40 R-DME-5633007 Regulation of TP53 Activity XP_046670960.1 M9MS40 R-DME-6804758 Regulation of TP53 Activity through Acetylation XP_046670960.1 M9MS40 R-DME-6811555 PI5P Regulates TP53 Acetylation XP_046670960.1 M9MS40 R-DME-73857 RNA Polymerase II Transcription XP_046670960.1 M9MS40 R-DME-74160 Gene expression (Transcription) XP_046670960.1 M9MS40 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046670960.1 M9MS40 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046670960.1 M9MS40 R-DME-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function XP_046670960.1 M9MS40 R-DME-8939211 ESR-mediated signaling XP_046670960.1 M9MS40 R-DME-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known XP_046670960.1 M9MS40 R-DME-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells XP_046670960.1 M9MS40 R-DME-8941858 Regulation of RUNX3 expression and activity XP_046670960.1 M9MS40 R-DME-8951936 RUNX3 regulates p14-ARF XP_046670960.1 M9MS40 R-DME-8953897 Cellular responses to stimuli XP_046670960.1 M9MS40 R-DME-9006931 Signaling by Nuclear Receptors XP_046670960.1 M9MS40 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046670960.1 M9MS40 R-DME-9018519 Estrogen-dependent gene expression XP_046670960.1 M9MS40 R-DME-9024446 NR1H2 and NR1H3-mediated signaling XP_046670960.1 M9MS40 R-DME-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux XP_046670960.1 M9MS40 R-DME-9614085 FOXO-mediated transcription XP_046670960.1 M9MS40 R-DME-9617629 Regulation of FOXO transcriptional activity by acetylation XP_046670960.1 M9MS40 R-DME-9701898 STAT3 nuclear events downstream of ALK signaling XP_046670960.1 M9MS40 R-DME-9707564 Cytoprotection by HMOX1 XP_046670960.1 M9MS40 R-DME-9711123 Cellular response to chemical stress XP_046670960.1 M9MS40 R-DME-9730414 MITF-M-regulated melanocyte development XP_046670960.1 M9MS40 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046670960.1 M9MS40 R-DME-9759194 Nuclear events mediated by NFE2L2 XP_046670960.1 M9MS40 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046670960.1 M9MS40 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046670960.1 M9MS40 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046670960.1 M9MS40 R-DME-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity XP_046670960.1 M9MS40 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046673422.1 A1Z9X0 R-DME-162582 Signal Transduction XP_046673422.1 A1Z9X0 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046673422.1 A1Z9X0 R-DME-194138 Signaling by VEGF XP_046673422.1 A1Z9X0 R-DME-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) XP_046673422.1 A1Z9X0 R-DME-2262752 Cellular responses to stress XP_046673422.1 A1Z9X0 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046673422.1 A1Z9X0 R-DME-5218921 VEGFR2 mediated cell proliferation XP_046673422.1 A1Z9X0 R-DME-8939211 ESR-mediated signaling XP_046673422.1 A1Z9X0 R-DME-8953897 Cellular responses to stimuli XP_046673422.1 A1Z9X0 R-DME-9006931 Signaling by Nuclear Receptors XP_046673422.1 A1Z9X0 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046673422.1 A1Z9X0 R-DME-9006936 Signaling by TGFB family members XP_046673422.1 A1Z9X0 R-DME-9009391 Extra-nuclear estrogen signaling XP_046673422.1 A1Z9X0 R-DME-9634635 Estrogen-stimulated signaling through PRKCZ XP_046673422.1 A1Z9X0 R-DME-9711123 Cellular response to chemical stress XP_046673422.1 A1Z9X0 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046670106.1 Q9W401 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046670106.1 Q9W401 R-DME-1430728 Metabolism XP_046670106.1 Q9W401 R-DME-392499 Metabolism of proteins XP_046670106.1 Q9W401 R-DME-71403 Citric acid cycle (TCA cycle) XP_046670106.1 Q9W401 R-DME-9837999 Mitochondrial protein degradation XP_046676389.1 Q9VKJ9 R-DME-1640170 Cell Cycle XP_046676389.1 Q9VKJ9 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046676389.1 Q9VKJ9 R-DME-2995410 Nuclear Envelope (NE) Reassembly XP_046676389.1 Q9VKJ9 R-DME-68882 Mitotic Anaphase XP_046676389.1 Q9VKJ9 R-DME-68886 M Phase XP_046676389.1 Q9VKJ9 R-DME-69278 Cell Cycle, Mitotic XP_046676389.1 Q9VKJ9 R-DME-9668328 Sealing of the nuclear envelope (NE) by ESCRT-III XP_046679655.1 Q9W0R3 R-DME-162582 Signal Transduction XP_046679655.1 Q9W0R3 R-DME-177929 Signaling by EGFR XP_046679655.1 Q9W0R3 R-DME-182971 EGFR downregulation XP_046679655.1 Q9W0R3 R-DME-5673001 RAF/MAP kinase cascade XP_046679655.1 Q9W0R3 R-DME-5675221 Negative regulation of MAPK pathway XP_046679655.1 Q9W0R3 R-DME-5683057 MAPK family signaling cascades XP_046679655.1 Q9W0R3 R-DME-5684996 MAPK1/MAPK3 signaling XP_046679655.1 Q9W0R3 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046667736.1 P32866 R-DME-162582 Signal Transduction XP_046667736.1 P32866 R-DME-372790 Signaling by GPCR XP_046667736.1 P32866 R-DME-388396 GPCR downstream signalling XP_046667736.1 P32866 R-DME-418555 G alpha (s) signalling events XP_046659444.1 Q95VU9 R-DME-390023 Subcellular localisation of D XP_046659444.1 Q95VU9 R-DME-390146 Hippo/Warts pathway XP_046659444.1 Q95VU9 R-DME-390150 DS ligand bound to FT receptor XP_046659444.1 Q95VU9 R-DME-390178 DS ligand not bound to FT receptor XP_046659444.1 Q95VU9 R-DME-5252538 Drosophila signaling pathways XP_046679479.1 Q8INJ8 R-DME-109582 Hemostasis XP_046679479.1 Q8INJ8 R-DME-1227986 Signaling by ERBB2 XP_046679479.1 Q8INJ8 R-DME-162582 Signal Transduction XP_046679479.1 Q8INJ8 R-DME-194315 Signaling by Rho GTPases XP_046679479.1 Q8INJ8 R-DME-354192 Integrin signaling XP_046679479.1 Q8INJ8 R-DME-76002 Platelet activation, signaling and aggregation XP_046679479.1 Q8INJ8 R-DME-76009 Platelet Aggregation (Plug Formation) XP_046679479.1 Q8INJ8 R-DME-8863795 Downregulation of ERBB2 signaling XP_046679479.1 Q8INJ8 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046679479.1 Q8INJ8 R-DME-9012999 RHO GTPase cycle XP_046679479.1 Q8INJ8 R-DME-9013407 RHOH GTPase cycle XP_046679479.1 Q8INJ8 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046665777.1 Q9VFG8 R-DME-162582 Signal Transduction XP_046665777.1 Q9VFG8 R-DME-2028269 Signaling by Hippo XP_046681876.1 Q9VEB1 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046681876.1 Q9VEB1 R-DME-1430728 Metabolism XP_046681876.1 Q9VEB1 R-DME-392499 Metabolism of proteins XP_046681876.1 Q9VEB1 R-DME-611105 Respiratory electron transport XP_046681876.1 Q9VEB1 R-DME-71403 Citric acid cycle (TCA cycle) XP_046681876.1 Q9VEB1 R-DME-9837999 Mitochondrial protein degradation XP_046681876.1 Q9VEB1 R-DME-9856872 Malate-aspartate shuttle XP_046662203.1 A0A0B4K6Y7 R-DME-109581 Apoptosis XP_046662203.1 A0A0B4K6Y7 R-DME-111465 Apoptotic cleavage of cellular proteins XP_046662203.1 A0A0B4K6Y7 R-DME-162582 Signal Transduction XP_046662203.1 A0A0B4K6Y7 R-DME-194315 Signaling by Rho GTPases XP_046662203.1 A0A0B4K6Y7 R-DME-2028269 Signaling by Hippo XP_046662203.1 A0A0B4K6Y7 R-DME-351906 Apoptotic cleavage of cell adhesion proteins XP_046662203.1 A0A0B4K6Y7 R-DME-5357801 Programmed Cell Death XP_046662203.1 A0A0B4K6Y7 R-DME-75153 Apoptotic execution phase XP_046662203.1 A0A0B4K6Y7 R-DME-8980692 RHOA GTPase cycle XP_046662203.1 A0A0B4K6Y7 R-DME-9012999 RHO GTPase cycle XP_046662203.1 A0A0B4K6Y7 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046659871.1 Q9W4S7 R-DME-212436 Generic Transcription Pathway XP_046659871.1 Q9W4S7 R-DME-73857 RNA Polymerase II Transcription XP_046659871.1 Q9W4S7 R-DME-74160 Gene expression (Transcription) XP_046659871.1 Q9W4S7 R-DME-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors XP_046659871.1 Q9W4S7 R-DME-8866911 TFAP2 (AP-2) family regulates transcription of cell cycle factors XP_046664322.1 Q9VKX2 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046664322.1 Q9VKX2 R-DME-1430728 Metabolism XP_046664322.1 Q9VKX2 R-DME-611105 Respiratory electron transport XP_046664322.1 Q9VKX2 R-DME-9856872 Malate-aspartate shuttle YP_214934.1 P18931 R-DME-1428517 Aerobic respiration and respiratory electron transport YP_214934.1 P18931 R-DME-1430728 Metabolism YP_214934.1 P18931 R-DME-392499 Metabolism of proteins YP_214934.1 P18931 R-DME-5368287 Mitochondrial translation YP_214934.1 P18931 R-DME-5419276 Mitochondrial translation termination YP_214934.1 P18931 R-DME-611105 Respiratory electron transport YP_214934.1 P18931 R-DME-6799198 Complex I biogenesis YP_214934.1 P18931 R-DME-72766 Translation XP_046687472.1 Q9VYH2 R-DME-1430728 Metabolism XP_046687472.1 Q9VYH2 R-DME-1630316 Glycosaminoglycan metabolism XP_046687472.1 Q9VYH2 R-DME-1793185 Chondroitin sulfate/dermatan sulfate metabolism XP_046687472.1 Q9VYH2 R-DME-2022870 CS-GAG biosynthesis XP_046687472.1 Q9VYH2 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046681145.1 M9NDS9 R-DME-168249 Innate Immune System XP_046681145.1 M9NDS9 R-DME-168256 Immune System XP_046681145.1 M9NDS9 R-DME-189085 Digestion of dietary carbohydrate XP_046681145.1 M9NDS9 R-DME-6798695 Neutrophil degranulation XP_046681145.1 M9NDS9 R-DME-8935690 Digestion XP_046681145.1 M9NDS9 R-DME-8963743 Digestion and absorption XP_046673666.1 Q9VMA2 R-DME-1430728 Metabolism XP_046673666.1 Q9VMA2 R-DME-70370 Galactose catabolism XP_046673666.1 Q9VMA2 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046677982.1 Q24216 R-DME-112382 Formation of RNA Pol II elongation complex XP_046677982.1 Q24216 R-DME-113418 Formation of the Early Elongation Complex XP_046677982.1 Q24216 R-DME-1640170 Cell Cycle XP_046677982.1 Q24216 R-DME-212436 Generic Transcription Pathway XP_046677982.1 Q24216 R-DME-3700989 Transcriptional Regulation by TP53 XP_046677982.1 Q24216 R-DME-453274 Mitotic G2-G2/M phases XP_046677982.1 Q24216 R-DME-453279 Mitotic G1 phase and G1/S transition XP_046677982.1 Q24216 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046677982.1 Q24216 R-DME-5696398 Nucleotide Excision Repair XP_046677982.1 Q24216 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046677982.1 Q24216 R-DME-674695 RNA Polymerase II Pre-transcription Events XP_046677982.1 Q24216 R-DME-6781823 Formation of TC-NER Pre-Incision Complex XP_046677982.1 Q24216 R-DME-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) XP_046677982.1 Q24216 R-DME-6782135 Dual incision in TC-NER XP_046677982.1 Q24216 R-DME-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER XP_046677982.1 Q24216 R-DME-6796648 TP53 Regulates Transcription of DNA Repair Genes XP_046677982.1 Q24216 R-DME-6807505 RNA polymerase II transcribes snRNA genes XP_046677982.1 Q24216 R-DME-69202 Cyclin E associated events during G1/S transition XP_046677982.1 Q24216 R-DME-69206 G1/S Transition XP_046677982.1 Q24216 R-DME-69231 Cyclin D associated events in G1 XP_046677982.1 Q24216 R-DME-69236 G1 Phase XP_046677982.1 Q24216 R-DME-69242 S Phase XP_046677982.1 Q24216 R-DME-69273 Cyclin A/B1/B2 associated events during G2/M transition XP_046677982.1 Q24216 R-DME-69275 G2/M Transition XP_046677982.1 Q24216 R-DME-69278 Cell Cycle, Mitotic XP_046677982.1 Q24216 R-DME-69656 Cyclin A:Cdk2-associated events at S phase entry XP_046677982.1 Q24216 R-DME-72086 mRNA Capping XP_046677982.1 Q24216 R-DME-73772 RNA Polymerase I Promoter Escape XP_046677982.1 Q24216 R-DME-73776 RNA Polymerase II Promoter Escape XP_046677982.1 Q24216 R-DME-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening XP_046677982.1 Q24216 R-DME-73854 RNA Polymerase I Promoter Clearance XP_046677982.1 Q24216 R-DME-73857 RNA Polymerase II Transcription XP_046677982.1 Q24216 R-DME-73864 RNA Polymerase I Transcription XP_046677982.1 Q24216 R-DME-73894 DNA Repair XP_046677982.1 Q24216 R-DME-74160 Gene expression (Transcription) XP_046677982.1 Q24216 R-DME-75953 RNA Polymerase II Transcription Initiation XP_046677982.1 Q24216 R-DME-75955 RNA Polymerase II Transcription Elongation XP_046677982.1 Q24216 R-DME-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance XP_046677982.1 Q24216 R-DME-77075 RNA Pol II CTD phosphorylation and interaction with CE XP_046677982.1 Q24216 R-DME-8878171 Transcriptional regulation by RUNX1 XP_046677982.1 Q24216 R-DME-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs XP_046677982.1 Q24216 R-DME-8953854 Metabolism of RNA XP_046685948.1 Q8IQF1 R-DME-1430728 Metabolism XP_046685948.1 Q8IQF1 R-DME-196849 Metabolism of water-soluble vitamins and cofactors XP_046685948.1 Q8IQF1 R-DME-196854 Metabolism of vitamins and cofactors XP_046685948.1 Q8IQF1 R-DME-947581 Molybdenum cofactor biosynthesis XP_046671825.1 Q8SXP0 R-DME-1430728 Metabolism XP_046671825.1 Q8SXP0 R-DME-1483191 Synthesis of PC XP_046671825.1 Q8SXP0 R-DME-1483206 Glycerophospholipid biosynthesis XP_046671825.1 Q8SXP0 R-DME-1483213 Synthesis of PE XP_046671825.1 Q8SXP0 R-DME-1483257 Phospholipid metabolism XP_046671825.1 Q8SXP0 R-DME-1640170 Cell Cycle XP_046671825.1 Q8SXP0 R-DME-2980766 Nuclear Envelope Breakdown XP_046671825.1 Q8SXP0 R-DME-4419969 Depolymerization of the Nuclear Lamina XP_046671825.1 Q8SXP0 R-DME-556833 Metabolism of lipids XP_046671825.1 Q8SXP0 R-DME-68875 Mitotic Prophase XP_046671825.1 Q8SXP0 R-DME-68886 M Phase XP_046671825.1 Q8SXP0 R-DME-69278 Cell Cycle, Mitotic XP_046671825.1 Q8SXP0 R-DME-75109 Triglyceride biosynthesis XP_046671825.1 Q8SXP0 R-DME-8979227 Triglyceride metabolism XP_046662430.1 A8JNT7 R-DME-1362409 Mitochondrial iron-sulfur cluster biogenesis XP_046662430.1 A8JNT7 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046662430.1 A8JNT7 R-DME-1430728 Metabolism XP_046662430.1 A8JNT7 R-DME-611105 Respiratory electron transport XP_046662430.1 A8JNT7 R-DME-6799198 Complex I biogenesis XP_046662430.1 A8JNT7 R-DME-9865881 Complex III assembly XP_046689165.1 Q9V6U8 R-DME-1280218 Adaptive Immune System XP_046689165.1 Q9V6U8 R-DME-168256 Immune System XP_046689165.1 Q9V6U8 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046689165.1 Q9V6U8 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046669094.1 Q24114 R-DME-109582 Hemostasis XP_046669094.1 Q24114 R-DME-1430728 Metabolism XP_046669094.1 Q24114 R-DME-162582 Signal Transduction XP_046669094.1 Q24114 R-DME-1630316 Glycosaminoglycan metabolism XP_046669094.1 Q24114 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046669094.1 Q24114 R-DME-1971475 Glycosaminoglycan-protein linkage region biosynthesis XP_046669094.1 Q24114 R-DME-2022928 HS-GAG biosynthesis XP_046669094.1 Q24114 R-DME-2024096 HS-GAG degradation XP_046669094.1 Q24114 R-DME-209392 Hedgehog pathway XP_046669094.1 Q24114 R-DME-209471 Formation and transport of the N-HH ligand XP_046669094.1 Q24114 R-DME-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) XP_046669094.1 Q24114 R-DME-392499 Metabolism of proteins XP_046669094.1 Q24114 R-DME-5252538 Drosophila signaling pathways XP_046669094.1 Q24114 R-DME-5358346 Hedgehog ligand biogenesis XP_046669094.1 Q24114 R-DME-5358351 Signaling by Hedgehog XP_046669094.1 Q24114 R-DME-5362798 Release of Hh-Np from the secreting cell XP_046669094.1 Q24114 R-DME-597592 Post-translational protein modification XP_046669094.1 Q24114 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046669094.1 Q24114 R-DME-8957275 Post-translational protein phosphorylation XP_046669094.1 Q24114 R-DME-9769739 Regulation of clotting cascade XP_046669094.1 Q24114 R-DME-9769740 Coagulation pathway XP_046667842.1 Q95RJ9 R-DME-1430728 Metabolism XP_046667842.1 Q95RJ9 R-DME-162582 Signal Transduction XP_046667842.1 Q95RJ9 R-DME-212165 Epigenetic regulation of gene expression XP_046667842.1 Q95RJ9 R-DME-212436 Generic Transcription Pathway XP_046667842.1 Q95RJ9 R-DME-2262752 Cellular responses to stress XP_046667842.1 Q95RJ9 R-DME-350054 Notch-HLH transcription pathway XP_046667842.1 Q95RJ9 R-DME-400206 Regulation of lipid metabolism by PPARalpha XP_046667842.1 Q95RJ9 R-DME-556833 Metabolism of lipids XP_046667842.1 Q95RJ9 R-DME-73857 RNA Polymerase II Transcription XP_046667842.1 Q95RJ9 R-DME-74160 Gene expression (Transcription) XP_046667842.1 Q95RJ9 R-DME-8953897 Cellular responses to stimuli XP_046667842.1 Q95RJ9 R-DME-9006931 Signaling by Nuclear Receptors XP_046667842.1 Q95RJ9 R-DME-9024446 NR1H2 and NR1H3-mediated signaling XP_046667842.1 Q95RJ9 R-DME-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux XP_046667842.1 Q95RJ9 R-DME-9707564 Cytoprotection by HMOX1 XP_046667842.1 Q95RJ9 R-DME-9711123 Cellular response to chemical stress XP_046667842.1 Q95RJ9 R-DME-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes XP_046667842.1 Q95RJ9 R-DME-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis XP_046667842.1 Q95RJ9 R-DME-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes XP_046667842.1 Q95RJ9 R-DME-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes XP_046679949.1 Q7KVW1 R-DME-109582 Hemostasis XP_046679949.1 Q7KVW1 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046661633.1 O15945 R-DME-1234158 Regulation of gene expression by Hypoxia-inducible Factor XP_046661633.1 O15945 R-DME-1234174 Cellular response to hypoxia XP_046661633.1 O15945 R-DME-1430728 Metabolism XP_046661633.1 O15945 R-DME-211859 Biological oxidations XP_046661633.1 O15945 R-DME-211945 Phase I - Functionalization of compounds XP_046661633.1 O15945 R-DME-212436 Generic Transcription Pathway XP_046661633.1 O15945 R-DME-2262752 Cellular responses to stress XP_046661633.1 O15945 R-DME-73857 RNA Polymerase II Transcription XP_046661633.1 O15945 R-DME-74160 Gene expression (Transcription) XP_046661633.1 O15945 R-DME-8937144 Aryl hydrocarbon receptor signalling XP_046661633.1 O15945 R-DME-8953897 Cellular responses to stimuli XP_046661633.1 O15945 R-DME-9634815 Transcriptional Regulation by NPAS4 XP_046661633.1 O15945 R-DME-9768919 NPAS4 regulates expression of target genes XP_046666130.1 Q9VAS8 R-DME-109582 Hemostasis XP_046666130.1 Q9VAS8 R-DME-162582 Signal Transduction XP_046666130.1 Q9VAS8 R-DME-194315 Signaling by Rho GTPases XP_046666130.1 Q9VAS8 R-DME-9012999 RHO GTPase cycle XP_046666130.1 Q9VAS8 R-DME-9013149 RAC1 GTPase cycle XP_046666130.1 Q9VAS8 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046666130.1 Q9VAS8 R-DME-983231 Factors involved in megakaryocyte development and platelet production XP_046681369.1 P08181 R-DME-1257604 PIP3 activates AKT signaling XP_046681369.1 P08181 R-DME-1266738 Developmental Biology XP_046681369.1 P08181 R-DME-162582 Signal Transduction XP_046681369.1 P08181 R-DME-1632852 Macroautophagy XP_046681369.1 P08181 R-DME-1640170 Cell Cycle XP_046681369.1 P08181 R-DME-195721 Signaling by WNT XP_046681369.1 P08181 R-DME-201681 TCF dependent signaling in response to WNT XP_046681369.1 P08181 R-DME-201688 WNT mediated activation of DVL XP_046681369.1 P08181 R-DME-209159 Assembly of the CI containing complexes XP_046681369.1 P08181 R-DME-209190 Phosphorylation of CI XP_046681369.1 P08181 R-DME-209214 Phosphorylation of SMO XP_046681369.1 P08181 R-DME-209392 Hedgehog pathway XP_046681369.1 P08181 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046681369.1 P08181 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046681369.1 P08181 R-DME-212436 Generic Transcription Pathway XP_046681369.1 P08181 R-DME-216217 Activation of SMO XP_046681369.1 P08181 R-DME-2514853 Condensation of Prometaphase Chromosomes XP_046681369.1 P08181 R-DME-3700989 Transcriptional Regulation by TP53 XP_046681369.1 P08181 R-DME-373760 L1CAM interactions XP_046681369.1 P08181 R-DME-390466 Chaperonin-mediated protein folding XP_046681369.1 P08181 R-DME-391251 Protein folding XP_046681369.1 P08181 R-DME-392499 Metabolism of proteins XP_046681369.1 P08181 R-DME-422475 Axon guidance XP_046681369.1 P08181 R-DME-432553 Phosphorylation of PER and TIM XP_046681369.1 P08181 R-DME-432626 Circadian Clock pathway XP_046681369.1 P08181 R-DME-445144 Signal transduction by L1 XP_046681369.1 P08181 R-DME-5205647 Mitophagy XP_046681369.1 P08181 R-DME-5252538 Drosophila signaling pathways XP_046681369.1 P08181 R-DME-5633007 Regulation of TP53 Activity XP_046681369.1 P08181 R-DME-6804756 Regulation of TP53 Activity through Phosphorylation XP_046681369.1 P08181 R-DME-6807070 PTEN Regulation XP_046681369.1 P08181 R-DME-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding XP_046681369.1 P08181 R-DME-68877 Mitotic Prometaphase XP_046681369.1 P08181 R-DME-68886 M Phase XP_046681369.1 P08181 R-DME-69278 Cell Cycle, Mitotic XP_046681369.1 P08181 R-DME-73857 RNA Polymerase II Transcription XP_046681369.1 P08181 R-DME-74160 Gene expression (Transcription) XP_046681369.1 P08181 R-DME-8934903 Receptor Mediated Mitophagy XP_046681369.1 P08181 R-DME-8948751 Regulation of PTEN stability and activity XP_046681369.1 P08181 R-DME-9006925 Intracellular signaling by second messengers XP_046681369.1 P08181 R-DME-9612973 Autophagy XP_046681369.1 P08181 R-DME-9663891 Selective autophagy XP_046681369.1 P08181 R-DME-9675108 Nervous system development XP_046682371.1 Q9VFP2 R-DME-1280218 Adaptive Immune System XP_046682371.1 Q9VFP2 R-DME-162582 Signal Transduction XP_046682371.1 Q9VFP2 R-DME-168256 Immune System XP_046682371.1 Q9VFP2 R-DME-209392 Hedgehog pathway XP_046682371.1 Q9VFP2 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046682371.1 Q9VFP2 R-DME-216167 Nuclear CI is degraded XP_046682371.1 Q9VFP2 R-DME-388841 Regulation of T cell activation by CD28 family XP_046682371.1 Q9VFP2 R-DME-389948 Co-inhibition by PD-1 XP_046682371.1 Q9VFP2 R-DME-5252538 Drosophila signaling pathways XP_046682371.1 Q9VFP2 R-DME-5358351 Signaling by Hedgehog XP_046682371.1 Q9VFP2 R-DME-5632684 Hedgehog 'on' state XP_046682371.1 Q9VFP2 R-DME-9909615 Regulation of PD-L1(CD274) Post-translational modification XP_046682371.1 Q9VFP2 R-DME-9909648 Regulation of PD-L1(CD274) expression XP_046682371.1 Q9VFP2 R-DME-9929491 SPOP-mediated proteasomal degradation of PD-L1(CD274) XP_046680833.1 Q9W328 R-DME-1257604 PIP3 activates AKT signaling XP_046680833.1 Q9W328 R-DME-1280218 Adaptive Immune System XP_046680833.1 Q9W328 R-DME-162582 Signal Transduction XP_046680833.1 Q9W328 R-DME-1632852 Macroautophagy XP_046680833.1 Q9W328 R-DME-165159 MTOR signalling XP_046680833.1 Q9W328 R-DME-166208 mTORC1-mediated signalling XP_046680833.1 Q9W328 R-DME-168256 Immune System XP_046680833.1 Q9W328 R-DME-194138 Signaling by VEGF XP_046680833.1 Q9W328 R-DME-212436 Generic Transcription Pathway XP_046680833.1 Q9W328 R-DME-2262752 Cellular responses to stress XP_046680833.1 Q9W328 R-DME-3371556 Cellular response to heat stress XP_046680833.1 Q9W328 R-DME-3371571 HSF1-dependent transactivation XP_046680833.1 Q9W328 R-DME-3700989 Transcriptional Regulation by TP53 XP_046680833.1 Q9W328 R-DME-380972 Energy dependent regulation of mTOR by LKB1-AMPK XP_046680833.1 Q9W328 R-DME-388841 Regulation of T cell activation by CD28 family XP_046680833.1 Q9W328 R-DME-389356 Co-stimulation by CD28 XP_046680833.1 Q9W328 R-DME-389357 CD28 dependent PI3K/Akt signaling XP_046680833.1 Q9W328 R-DME-4420097 VEGFA-VEGFR2 Pathway XP_046680833.1 Q9W328 R-DME-5218920 VEGFR2 mediated vascular permeability XP_046680833.1 Q9W328 R-DME-5628897 TP53 Regulates Metabolic Genes XP_046680833.1 Q9W328 R-DME-6807070 PTEN Regulation XP_046680833.1 Q9W328 R-DME-73857 RNA Polymerase II Transcription XP_046680833.1 Q9W328 R-DME-74160 Gene expression (Transcription) XP_046680833.1 Q9W328 R-DME-8943724 Regulation of PTEN gene transcription XP_046680833.1 Q9W328 R-DME-8953897 Cellular responses to stimuli XP_046680833.1 Q9W328 R-DME-9006925 Intracellular signaling by second messengers XP_046680833.1 Q9W328 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046680833.1 Q9W328 R-DME-9612973 Autophagy XP_046680833.1 Q9W328 R-DME-9639288 Amino acids regulate mTORC1 XP_046680833.1 Q9W328 R-DME-9711097 Cellular response to starvation XP_046680833.1 Q9W328 R-DME-9855142 Cellular responses to mechanical stimuli XP_046680833.1 Q9W328 R-DME-9856530 High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells XP_046680833.1 Q9W328 R-DME-9860931 Response of endothelial cells to shear stress XP_046682136.1 O97102 R-DME-1430728 Metabolism XP_046682136.1 O97102 R-DME-196791 Vitamin D (calciferol) metabolism XP_046682136.1 O97102 R-DME-2990846 SUMOylation XP_046682136.1 O97102 R-DME-3065679 SUMO is proteolytically processed XP_046682136.1 O97102 R-DME-3108214 SUMOylation of DNA damage response and repair proteins XP_046682136.1 O97102 R-DME-3108232 SUMO E3 ligases SUMOylate target proteins XP_046682136.1 O97102 R-DME-3215018 Processing and activation of SUMO XP_046682136.1 O97102 R-DME-3232118 SUMOylation of transcription factors XP_046682136.1 O97102 R-DME-3899300 SUMOylation of transcription cofactors XP_046682136.1 O97102 R-DME-392499 Metabolism of proteins XP_046682136.1 O97102 R-DME-4085377 SUMOylation of SUMOylation proteins XP_046682136.1 O97102 R-DME-4090294 SUMOylation of intracellular receptors XP_046682136.1 O97102 R-DME-4551638 SUMOylation of chromatin organization proteins XP_046682136.1 O97102 R-DME-4570464 SUMOylation of RNA binding proteins XP_046682136.1 O97102 R-DME-4615885 SUMOylation of DNA replication proteins XP_046682136.1 O97102 R-DME-4755510 SUMOylation of immune response proteins XP_046682136.1 O97102 R-DME-556833 Metabolism of lipids XP_046682136.1 O97102 R-DME-5696395 Formation of Incision Complex in GG-NER XP_046682136.1 O97102 R-DME-5696398 Nucleotide Excision Repair XP_046682136.1 O97102 R-DME-5696399 Global Genome Nucleotide Excision Repair (GG-NER) XP_046682136.1 O97102 R-DME-597592 Post-translational protein modification XP_046682136.1 O97102 R-DME-73894 DNA Repair XP_046682136.1 O97102 R-DME-8957322 Metabolism of steroids XP_046675582.1 Q9VSJ6 R-DME-162582 Signal Transduction XP_046675582.1 Q9VSJ6 R-DME-5358351 Signaling by Hedgehog XP_046675582.1 Q9VSJ6 R-DME-5610787 Hedgehog 'off' state XP_046672971.1 A0A0B4LFW5 R-DME-1430728 Metabolism XP_046672971.1 A0A0B4LFW5 R-DME-168249 Innate Immune System XP_046672971.1 A0A0B4LFW5 R-DME-168256 Immune System XP_046672971.1 A0A0B4LFW5 R-DME-3322077 Glycogen synthesis XP_046672971.1 A0A0B4LFW5 R-DME-6798695 Neutrophil degranulation XP_046672971.1 A0A0B4LFW5 R-DME-70221 Glycogen breakdown (glycogenolysis) XP_046672971.1 A0A0B4LFW5 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046672971.1 A0A0B4LFW5 R-DME-8982491 Glycogen metabolism XP_046669632.1 Q9VHT4 R-DME-382551 Transport of small molecules XP_046669632.1 Q9VHT4 R-DME-392499 Metabolism of proteins XP_046669632.1 Q9VHT4 R-DME-425397 Transport of vitamins, nucleosides, and related molecules XP_046669632.1 Q9VHT4 R-DME-425407 SLC-mediated transmembrane transport XP_046669632.1 Q9VHT4 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046669632.1 Q9VHT4 R-DME-446203 Asparagine N-linked glycosylation XP_046669632.1 Q9VHT4 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046669632.1 Q9VHT4 R-DME-597592 Post-translational protein modification XP_046669632.1 Q9VHT4 R-DME-6787639 GDP-fucose biosynthesis XP_046669632.1 Q9VHT4 R-DME-727802 Transport of nucleotide sugars XP_046676136.1 Q9W3I9 R-DME-1280215 Cytokine Signaling in Immune system XP_046676136.1 Q9W3I9 R-DME-166016 Toll Like Receptor 4 (TLR4) Cascade XP_046676136.1 Q9W3I9 R-DME-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane XP_046676136.1 Q9W3I9 R-DME-166166 MyD88-independent TLR4 cascade XP_046676136.1 Q9W3I9 R-DME-168138 Toll Like Receptor 9 (TLR9) Cascade XP_046676136.1 Q9W3I9 R-DME-168142 Toll Like Receptor 10 (TLR10) Cascade XP_046676136.1 Q9W3I9 R-DME-168164 Toll Like Receptor 3 (TLR3) Cascade XP_046676136.1 Q9W3I9 R-DME-168176 Toll Like Receptor 5 (TLR5) Cascade XP_046676136.1 Q9W3I9 R-DME-168179 Toll Like Receptor TLR1:TLR2 Cascade XP_046676136.1 Q9W3I9 R-DME-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade XP_046676136.1 Q9W3I9 R-DME-168188 Toll Like Receptor TLR6:TLR2 Cascade XP_046676136.1 Q9W3I9 R-DME-168249 Innate Immune System XP_046676136.1 Q9W3I9 R-DME-168256 Immune System XP_046676136.1 Q9W3I9 R-DME-168898 Toll-like Receptor Cascades XP_046676136.1 Q9W3I9 R-DME-181438 Toll Like Receptor 2 (TLR2) Cascade XP_046676136.1 Q9W3I9 R-DME-392499 Metabolism of proteins XP_046676136.1 Q9W3I9 R-DME-445989 TAK1-dependent IKK and NF-kappa-B activation XP_046676136.1 Q9W3I9 R-DME-446652 Interleukin-1 family signaling XP_046676136.1 Q9W3I9 R-DME-448424 Interleukin-17 signaling XP_046676136.1 Q9W3I9 R-DME-449147 Signaling by Interleukins XP_046676136.1 Q9W3I9 R-DME-450294 MAP kinase activation XP_046676136.1 Q9W3I9 R-DME-450302 activated TAK1 mediates p38 MAPK activation XP_046676136.1 Q9W3I9 R-DME-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 XP_046676136.1 Q9W3I9 R-DME-5688426 Deubiquitination XP_046676136.1 Q9W3I9 R-DME-5689880 Ub-specific processing proteases XP_046676136.1 Q9W3I9 R-DME-5689896 Ovarian tumor domain proteases XP_046676136.1 Q9W3I9 R-DME-597592 Post-translational protein modification XP_046676136.1 Q9W3I9 R-DME-9020702 Interleukin-1 signaling XP_046676136.1 Q9W3I9 R-DME-937039 IRAK1 recruits IKK complex XP_046676136.1 Q9W3I9 R-DME-937042 IRAK2 mediated activation of TAK1 complex XP_046676136.1 Q9W3I9 R-DME-937061 TRIF (TICAM1)-mediated TLR4 signaling XP_046676136.1 Q9W3I9 R-DME-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex XP_046676136.1 Q9W3I9 R-DME-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation XP_046676136.1 Q9W3I9 R-DME-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation XP_046676136.1 Q9W3I9 R-DME-975155 MyD88 dependent cascade initiated on endosome XP_046676136.1 Q9W3I9 R-DME-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation XP_046676136.1 Q9W3I9 R-DME-975871 MyD88 cascade initiated on plasma membrane XP_046668062.1 Q95V18 R-DME-110523 TOR signaling pathway XP_046668062.1 Q95V18 R-DME-110526 Insulin receptor mediated signaling XP_046668062.1 Q95V18 R-DME-5252538 Drosophila signaling pathways XP_046668062.1 Q9VMF3 R-DME-162582 Signal Transduction XP_046668062.1 Q9VMF3 R-DME-5673001 RAF/MAP kinase cascade XP_046668062.1 Q9VMF3 R-DME-5683057 MAPK family signaling cascades XP_046668062.1 Q9VMF3 R-DME-5684996 MAPK1/MAPK3 signaling XP_046673240.1 Q9V730 R-DME-1430728 Metabolism XP_046673240.1 Q9V730 R-DME-1630316 Glycosaminoglycan metabolism XP_046673240.1 Q9V730 R-DME-1638091 Heparan sulfate/heparin (HS-GAG) metabolism XP_046673240.1 Q9V730 R-DME-2022928 HS-GAG biosynthesis XP_046673240.1 Q9V730 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682262.1 Q9VFC8 R-DME-1430728 Metabolism XP_046682262.1 Q9VFC8 R-DME-3322077 Glycogen synthesis XP_046682262.1 Q9VFC8 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046682262.1 Q9VFC8 R-DME-8982491 Glycogen metabolism XP_046658452.1 Q9V9S8 R-DME-1430728 Metabolism XP_046658452.1 Q9V9S8 R-DME-189445 Metabolism of porphyrins XP_046658452.1 Q9V9S8 R-DME-189451 Heme biosynthesis XP_046658452.1 Q9V9S8 R-DME-392499 Metabolism of proteins XP_046658452.1 Q9V9S8 R-DME-9837999 Mitochondrial protein degradation XP_046658544.1 Q24167 R-DME-1234158 Regulation of gene expression by Hypoxia-inducible Factor XP_046658544.1 Q24167 R-DME-1234174 Cellular response to hypoxia XP_046658544.1 Q24167 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046658544.1 Q24167 R-DME-2262752 Cellular responses to stress XP_046658544.1 Q24167 R-DME-392499 Metabolism of proteins XP_046658544.1 Q24167 R-DME-597592 Post-translational protein modification XP_046658544.1 Q24167 R-DME-8951664 Neddylation XP_046658544.1 Q24167 R-DME-8953897 Cellular responses to stimuli XP_046684896.1 Q9VZU4 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046684896.1 Q9VZU4 R-DME-1430728 Metabolism XP_046684896.1 Q9VZU4 R-DME-392499 Metabolism of proteins XP_046684896.1 Q9VZU4 R-DME-611105 Respiratory electron transport XP_046684896.1 Q9VZU4 R-DME-6799198 Complex I biogenesis XP_046684896.1 Q9VZU4 R-DME-9837999 Mitochondrial protein degradation XP_046677213.1 Q7JWD6 R-DME-112382 Formation of RNA Pol II elongation complex XP_046677213.1 Q7JWD6 R-DME-1234174 Cellular response to hypoxia XP_046677213.1 Q7JWD6 R-DME-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha XP_046677213.1 Q7JWD6 R-DME-1280218 Adaptive Immune System XP_046677213.1 Q7JWD6 R-DME-168256 Immune System XP_046677213.1 Q7JWD6 R-DME-212436 Generic Transcription Pathway XP_046677213.1 Q7JWD6 R-DME-2262752 Cellular responses to stress XP_046677213.1 Q7JWD6 R-DME-3700989 Transcriptional Regulation by TP53 XP_046677213.1 Q7JWD6 R-DME-392499 Metabolism of proteins XP_046677213.1 Q7JWD6 R-DME-597592 Post-translational protein modification XP_046677213.1 Q7JWD6 R-DME-674695 RNA Polymerase II Pre-transcription Events XP_046677213.1 Q7JWD6 R-DME-6796648 TP53 Regulates Transcription of DNA Repair Genes XP_046677213.1 Q7JWD6 R-DME-72766 Translation XP_046677213.1 Q7JWD6 R-DME-73857 RNA Polymerase II Transcription XP_046677213.1 Q7JWD6 R-DME-74160 Gene expression (Transcription) XP_046677213.1 Q7JWD6 R-DME-75955 RNA Polymerase II Transcription Elongation XP_046677213.1 Q7JWD6 R-DME-8951664 Neddylation XP_046677213.1 Q7JWD6 R-DME-8953897 Cellular responses to stimuli XP_046677213.1 Q7JWD6 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046677213.1 Q7JWD6 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046677213.1 Q7JWD6 R-DME-9948299 Ribosome-associated quality control XP_046677213.1 Q7JWD6 R-DME-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide XP_046684079.1 Q9VR53 R-DME-392499 Metabolism of proteins XP_046684079.1 Q9VR53 R-DME-597592 Post-translational protein modification XP_046684079.1 Q9VR53 R-DME-8951664 Neddylation XP_046663990.1 M9PDM4 R-DME-1430728 Metabolism XP_046663990.1 M9PDM4 R-DME-1483248 Synthesis of PIPs at the ER membrane XP_046663990.1 M9PDM4 R-DME-1483255 PI Metabolism XP_046663990.1 M9PDM4 R-DME-1483257 Phospholipid metabolism XP_046663990.1 M9PDM4 R-DME-1660514 Synthesis of PIPs at the Golgi membrane XP_046663990.1 M9PDM4 R-DME-556833 Metabolism of lipids XP_046677215.1 O62619 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046677215.1 O62619 R-DME-1430728 Metabolism XP_046677215.1 O62619 R-DME-168249 Innate Immune System XP_046677215.1 O62619 R-DME-168256 Immune System XP_046677215.1 O62619 R-DME-6798695 Neutrophil degranulation XP_046677215.1 O62619 R-DME-70171 Glycolysis XP_046677215.1 O62619 R-DME-70268 Pyruvate metabolism XP_046677215.1 O62619 R-DME-70326 Glucose metabolism XP_046677215.1 O62619 R-DME-71387 Metabolism of carbohydrates and carbohydrate derivatives XP_046677215.1 O62619 R-DME-9861718 Regulation of pyruvate metabolism XP_046671513.1 Q9W0G1 R-DME-1169410 Antimicrobial mechanism of IFN-stimulated genes XP_046671513.1 Q9W0G1 R-DME-1280215 Cytokine Signaling in Immune system XP_046671513.1 Q9W0G1 R-DME-162582 Signal Transduction XP_046671513.1 Q9W0G1 R-DME-168256 Immune System XP_046671513.1 Q9W0G1 R-DME-74752 Signaling by Insulin receptor XP_046671513.1 Q9W0G1 R-DME-77387 Insulin receptor recycling XP_046671513.1 Q9W0G1 R-DME-877300 Interferon gamma signaling XP_046671513.1 Q9W0G1 R-DME-877312 Regulation of IFNG signaling XP_046671513.1 Q9W0G1 R-DME-8953897 Cellular responses to stimuli XP_046671513.1 Q9W0G1 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046671513.1 Q9W0G1 R-DME-913531 Interferon Signaling XP_046671513.1 Q9W0G1 R-DME-9833482 PKR-mediated signaling XP_046671513.1 Q9W0G1 R-DME-9855142 Cellular responses to mechanical stimuli XP_046671513.1 Q9W0G1 R-DME-9860927 Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells XP_046671513.1 Q9W0G1 R-DME-9860931 Response of endothelial cells to shear stress XP_046669059.1 Q9W1X8 R-DME-392499 Metabolism of proteins XP_046669059.1 Q9W1X8 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046669059.1 Q9W1X8 R-DME-446203 Asparagine N-linked glycosylation XP_046669059.1 Q9W1X8 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046669059.1 Q9W1X8 R-DME-597592 Post-translational protein modification XP_046669059.1 Q9W1X8 R-DME-6787639 GDP-fucose biosynthesis XP_046685965.1 Q7JXA2 R-DME-1257604 PIP3 activates AKT signaling XP_046685965.1 Q7JXA2 R-DME-162582 Signal Transduction XP_046685965.1 Q7JXA2 R-DME-165159 MTOR signalling XP_046685965.1 Q7JXA2 R-DME-166208 mTORC1-mediated signalling XP_046685965.1 Q7JXA2 R-DME-198323 AKT phosphorylates targets in the cytosol XP_046685965.1 Q7JXA2 R-DME-2262752 Cellular responses to stress XP_046685965.1 Q7JXA2 R-DME-3371556 Cellular response to heat stress XP_046685965.1 Q7JXA2 R-DME-3371571 HSF1-dependent transactivation XP_046685965.1 Q7JXA2 R-DME-8953897 Cellular responses to stimuli XP_046685965.1 Q7JXA2 R-DME-9006925 Intracellular signaling by second messengers XP_046664104.1 Q9VS84 R-DME-112316 Neuronal System XP_046664104.1 Q9VS84 R-DME-162582 Signal Transduction XP_046664104.1 Q9VS84 R-DME-177929 Signaling by EGFR XP_046664104.1 Q9VS84 R-DME-193634 Axonal growth inhibition (RHOA activation) XP_046664104.1 Q9VS84 R-DME-193697 p75NTR regulates axonogenesis XP_046664104.1 Q9VS84 R-DME-193704 p75 NTR receptor-mediated signalling XP_046664104.1 Q9VS84 R-DME-6794361 Neurexins and neuroligins XP_046664104.1 Q9VS84 R-DME-6794362 Protein-protein interactions at synapses XP_046664104.1 Q9VS84 R-DME-73887 Death Receptor Signaling XP_046664104.1 Q9VS84 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046659067.1 O44382 R-DME-209360 Ubiquitination and proteolysis of phosphorylated CI XP_046659067.1 O44382 R-DME-209392 Hedgehog pathway XP_046659067.1 O44382 R-DME-209412 Wingless pathway XP_046659067.1 O44382 R-DME-209441 WG ligand not bound to FZ receptors XP_046659067.1 O44382 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046659067.1 O44382 R-DME-209461 Ubiquitination and degradation of phosphorylated ARM XP_046659067.1 O44382 R-DME-432524 Degradation of PER XP_046659067.1 O44382 R-DME-432626 Circadian Clock pathway XP_046659067.1 O44382 R-DME-5252538 Drosophila signaling pathways XP_046673560.1 Q9Y162 R-DME-1640170 Cell Cycle XP_046673560.1 Q9Y162 R-DME-2555396 Mitotic Metaphase and Anaphase XP_046673560.1 Q9Y162 R-DME-2995410 Nuclear Envelope (NE) Reassembly XP_046673560.1 Q9Y162 R-DME-68882 Mitotic Anaphase XP_046673560.1 Q9Y162 R-DME-68886 M Phase XP_046673560.1 Q9Y162 R-DME-69278 Cell Cycle, Mitotic XP_046673560.1 Q9Y162 R-DME-9668328 Sealing of the nuclear envelope (NE) by ESCRT-III XP_046680608.1 P91656 R-DME-110523 TOR signaling pathway XP_046680608.1 P91656 R-DME-110526 Insulin receptor mediated signaling XP_046680608.1 P91656 R-DME-5252538 Drosophila signaling pathways XP_046680608.1 Q94533 R-DME-1257604 PIP3 activates AKT signaling XP_046680608.1 Q94533 R-DME-162582 Signal Transduction XP_046680608.1 Q94533 R-DME-165159 MTOR signalling XP_046680608.1 Q94533 R-DME-166208 mTORC1-mediated signalling XP_046680608.1 Q94533 R-DME-198693 AKT phosphorylates targets in the nucleus XP_046680608.1 Q94533 R-DME-9006925 Intracellular signaling by second messengers XP_046680148.1 Q9VWQ2 R-DME-1257604 PIP3 activates AKT signaling XP_046680148.1 Q9VWQ2 R-DME-162582 Signal Transduction XP_046680148.1 Q9VWQ2 R-DME-198693 AKT phosphorylates targets in the nucleus XP_046680148.1 Q9VWQ2 R-DME-9006925 Intracellular signaling by second messengers XP_046665704.1 P09208 R-DME-110478 Insulin signaling pathway XP_046665704.1 P09208 R-DME-110526 Insulin receptor mediated signaling XP_046665704.1 P09208 R-DME-162582 Signal Transduction XP_046665704.1 P09208 R-DME-5252538 Drosophila signaling pathways XP_046665704.1 P09208 R-DME-74752 Signaling by Insulin receptor XP_046665704.1 P09208 R-DME-77387 Insulin receptor recycling XP_046665704.1 P09208 R-DME-8939211 ESR-mediated signaling XP_046665704.1 P09208 R-DME-9006931 Signaling by Nuclear Receptors XP_046665704.1 P09208 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046665704.1 P09208 R-DME-9009391 Extra-nuclear estrogen signaling XP_046680851.1 Q9W0I6 R-DME-1430728 Metabolism XP_046680851.1 Q9W0I6 R-DME-1483248 Synthesis of PIPs at the ER membrane XP_046680851.1 Q9W0I6 R-DME-1483255 PI Metabolism XP_046680851.1 Q9W0I6 R-DME-1483257 Phospholipid metabolism XP_046680851.1 Q9W0I6 R-DME-1660514 Synthesis of PIPs at the Golgi membrane XP_046680851.1 Q9W0I6 R-DME-556833 Metabolism of lipids XP_046672330.1 Q9VM14 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046672330.1 Q9VM14 R-DME-1430728 Metabolism XP_046672330.1 Q9VM14 R-DME-162582 Signal Transduction XP_046672330.1 Q9VM14 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046672330.1 Q9VM14 R-DME-392499 Metabolism of proteins XP_046672330.1 Q9VM14 R-DME-5362517 Signaling by Retinoic Acid XP_046672330.1 Q9VM14 R-DME-597592 Post-translational protein modification XP_046672330.1 Q9VM14 R-DME-70268 Pyruvate metabolism XP_046672330.1 Q9VM14 R-DME-9006931 Signaling by Nuclear Receptors XP_046672330.1 Q9VM14 R-DME-9857492 Protein lipoylation XP_046672330.1 Q9VM14 R-DME-9861559 PDH complex synthesizes acetyl-CoA from PYR XP_046672330.1 Q9VM14 R-DME-9861718 Regulation of pyruvate metabolism XP_046675320.1 P09615 R-DME-162582 Signal Transduction XP_046675320.1 P09615 R-DME-195721 Signaling by WNT XP_046675320.1 P09615 R-DME-201681 TCF dependent signaling in response to WNT XP_046675320.1 P09615 R-DME-209387 Phosphorylation of ARR XP_046675320.1 P09615 R-DME-209412 Wingless pathway XP_046675320.1 P09615 R-DME-209440 Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM XP_046675320.1 P09615 R-DME-209469 WG ligand bound to FZ receptors XP_046675320.1 P09615 R-DME-209472 Assembly of receptor complex XP_046675320.1 P09615 R-DME-3238698 WNT ligand biogenesis and trafficking XP_046675320.1 P09615 R-DME-3858494 Beta-catenin independent WNT signaling XP_046675320.1 P09615 R-DME-4086400 PCP/CE pathway XP_046675320.1 P09615 R-DME-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane XP_046675320.1 P09615 R-DME-5252538 Drosophila signaling pathways XP_046664751.1 Q24292 R-DME-350379 Homo-/heterophilic binding of transmembrane components XP_046664751.1 Q24292 R-DME-350431 Planar Cell Polarity pathway XP_046664751.1 Q24292 R-DME-390023 Subcellular localisation of D XP_046664751.1 Q24292 R-DME-390146 Hippo/Warts pathway XP_046664751.1 Q24292 R-DME-390150 DS ligand bound to FT receptor XP_046664751.1 Q24292 R-DME-5252538 Drosophila signaling pathways XP_046658500.1 O02194 R-DME-1236394 Signaling by ERBB4 XP_046658500.1 O02194 R-DME-1251985 Nuclear signaling by ERBB4 XP_046658500.1 O02194 R-DME-1266738 Developmental Biology XP_046658500.1 O02194 R-DME-162582 Signal Transduction XP_046658500.1 O02194 R-DME-168249 Innate Immune System XP_046658500.1 O02194 R-DME-168256 Immune System XP_046658500.1 O02194 R-DME-2682334 EPH-Ephrin signaling XP_046658500.1 O02194 R-DME-3928665 EPH-ephrin mediated repulsion of cells XP_046658500.1 O02194 R-DME-422475 Axon guidance XP_046658500.1 O02194 R-DME-6798695 Neutrophil degranulation XP_046658500.1 O02194 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046658500.1 O02194 R-DME-9675108 Nervous system development XP_046685648.1 Q09147 R-DME-109704 PI3K Cascade XP_046685648.1 Q09147 R-DME-112399 IRS-mediated signalling XP_046685648.1 Q09147 R-DME-1257604 PIP3 activates AKT signaling XP_046685648.1 Q09147 R-DME-1266738 Developmental Biology XP_046685648.1 Q09147 R-DME-1307965 betaKlotho-mediated ligand binding XP_046685648.1 Q09147 R-DME-162582 Signal Transduction XP_046685648.1 Q09147 R-DME-190236 Signaling by FGFR XP_046685648.1 Q09147 R-DME-190239 FGFR3 ligand binding and activation XP_046685648.1 Q09147 R-DME-190241 FGFR2 ligand binding and activation XP_046685648.1 Q09147 R-DME-190242 FGFR1 ligand binding and activation XP_046685648.1 Q09147 R-DME-190322 FGFR4 ligand binding and activation XP_046685648.1 Q09147 R-DME-190370 FGFR1b ligand binding and activation XP_046685648.1 Q09147 R-DME-190371 FGFR3b ligand binding and activation XP_046685648.1 Q09147 R-DME-190372 FGFR3c ligand binding and activation XP_046685648.1 Q09147 R-DME-190373 FGFR1c ligand binding and activation XP_046685648.1 Q09147 R-DME-190374 FGFR1c and Klotho ligand binding and activation XP_046685648.1 Q09147 R-DME-190375 FGFR2c ligand binding and activation XP_046685648.1 Q09147 R-DME-190377 FGFR2b ligand binding and activation XP_046685648.1 Q09147 R-DME-199418 Negative regulation of the PI3K/AKT network XP_046685648.1 Q09147 R-DME-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) XP_046685648.1 Q09147 R-DME-2428924 IGF1R signaling cascade XP_046685648.1 Q09147 R-DME-2428928 IRS-related events triggered by IGF1R XP_046685648.1 Q09147 R-DME-373760 L1CAM interactions XP_046685648.1 Q09147 R-DME-422475 Axon guidance XP_046685648.1 Q09147 R-DME-445144 Signal transduction by L1 XP_046685648.1 Q09147 R-DME-5654219 Phospholipase C-mediated cascade: FGFR1 XP_046685648.1 Q09147 R-DME-5654221 Phospholipase C-mediated cascade; FGFR2 XP_046685648.1 Q09147 R-DME-5654227 Phospholipase C-mediated cascade; FGFR3 XP_046685648.1 Q09147 R-DME-5654228 Phospholipase C-mediated cascade; FGFR4 XP_046685648.1 Q09147 R-DME-5654687 Downstream signaling of activated FGFR1 XP_046685648.1 Q09147 R-DME-5654688 SHC-mediated cascade:FGFR1 XP_046685648.1 Q09147 R-DME-5654689 PI-3K cascade:FGFR1 XP_046685648.1 Q09147 R-DME-5654693 FRS-mediated FGFR1 signaling XP_046685648.1 Q09147 R-DME-5654695 PI-3K cascade:FGFR2 XP_046685648.1 Q09147 R-DME-5654696 Downstream signaling of activated FGFR2 XP_046685648.1 Q09147 R-DME-5654699 SHC-mediated cascade:FGFR2 XP_046685648.1 Q09147 R-DME-5654700 FRS-mediated FGFR2 signaling XP_046685648.1 Q09147 R-DME-5654704 SHC-mediated cascade:FGFR3 XP_046685648.1 Q09147 R-DME-5654706 FRS-mediated FGFR3 signaling XP_046685648.1 Q09147 R-DME-5654708 Downstream signaling of activated FGFR3 XP_046685648.1 Q09147 R-DME-5654710 PI-3K cascade:FGFR3 XP_046685648.1 Q09147 R-DME-5654712 FRS-mediated FGFR4 signaling XP_046685648.1 Q09147 R-DME-5654716 Downstream signaling of activated FGFR4 XP_046685648.1 Q09147 R-DME-5654719 SHC-mediated cascade:FGFR4 XP_046685648.1 Q09147 R-DME-5654720 PI-3K cascade:FGFR4 XP_046685648.1 Q09147 R-DME-5654726 Negative regulation of FGFR1 signaling XP_046685648.1 Q09147 R-DME-5654727 Negative regulation of FGFR2 signaling XP_046685648.1 Q09147 R-DME-5654732 Negative regulation of FGFR3 signaling XP_046685648.1 Q09147 R-DME-5654733 Negative regulation of FGFR4 signaling XP_046685648.1 Q09147 R-DME-5654736 Signaling by FGFR1 XP_046685648.1 Q09147 R-DME-5654738 Signaling by FGFR2 XP_046685648.1 Q09147 R-DME-5654741 Signaling by FGFR3 XP_046685648.1 Q09147 R-DME-5654743 Signaling by FGFR4 XP_046685648.1 Q09147 R-DME-5673001 RAF/MAP kinase cascade XP_046685648.1 Q09147 R-DME-5683057 MAPK family signaling cascades XP_046685648.1 Q09147 R-DME-5684996 MAPK1/MAPK3 signaling XP_046685648.1 Q09147 R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling XP_046685648.1 Q09147 R-DME-74751 Insulin receptor signalling cascade XP_046685648.1 Q09147 R-DME-74752 Signaling by Insulin receptor XP_046685648.1 Q09147 R-DME-9006925 Intracellular signaling by second messengers XP_046685648.1 Q09147 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046685648.1 Q09147 R-DME-9675108 Nervous system development XP_046664517.1 Q7KNQ9 R-DME-162582 Signal Transduction XP_046664517.1 Q7KNQ9 R-DME-209159 Assembly of the CI containing complexes XP_046664517.1 Q7KNQ9 R-DME-209190 Phosphorylation of CI XP_046664517.1 Q7KNQ9 R-DME-209214 Phosphorylation of SMO XP_046664517.1 Q7KNQ9 R-DME-209392 Hedgehog pathway XP_046664517.1 Q7KNQ9 R-DME-209446 N-HH ligand not bound to PTC receptor complex XP_046664517.1 Q7KNQ9 R-DME-209452 N-HH ligand bound to PTC receptor complex XP_046664517.1 Q7KNQ9 R-DME-216217 Activation of SMO XP_046664517.1 Q7KNQ9 R-DME-432553 Phosphorylation of PER and TIM XP_046664517.1 Q7KNQ9 R-DME-432626 Circadian Clock pathway XP_046664517.1 Q7KNQ9 R-DME-5252538 Drosophila signaling pathways XP_046664517.1 Q7KNQ9 R-DME-5673001 RAF/MAP kinase cascade XP_046664517.1 Q7KNQ9 R-DME-5674135 MAP2K and MAPK activation XP_046664517.1 Q7KNQ9 R-DME-5683057 MAPK family signaling cascades XP_046664517.1 Q7KNQ9 R-DME-5684996 MAPK1/MAPK3 signaling XP_046664892.1 Q9W3X6 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046664892.1 Q9W3X6 R-DME-1430728 Metabolism XP_046664892.1 Q9W3X6 R-DME-392499 Metabolism of proteins XP_046664892.1 Q9W3X6 R-DME-71403 Citric acid cycle (TCA cycle) XP_046664892.1 Q9W3X6 R-DME-9837999 Mitochondrial protein degradation XP_046671993.1 Q9VH77 R-DME-392499 Metabolism of proteins XP_046671993.1 Q9VH77 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046671993.1 Q9VH77 R-DME-446203 Asparagine N-linked glycosylation XP_046671993.1 Q9VH77 R-DME-446205 Synthesis of GDP-mannose XP_046671993.1 Q9VH77 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046671993.1 Q9VH77 R-DME-597592 Post-translational protein modification XP_046661916.1 Q7KN62 R-DME-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template XP_046661916.1 Q7KN62 R-DME-110320 Translesion Synthesis by POLH XP_046661916.1 Q7KN62 R-DME-162582 Signal Transduction XP_046661916.1 Q7KN62 R-DME-168249 Innate Immune System XP_046661916.1 Q7KN62 R-DME-168256 Immune System XP_046661916.1 Q7KN62 R-DME-194315 Signaling by Rho GTPases XP_046661916.1 Q7KN62 R-DME-2262752 Cellular responses to stress XP_046661916.1 Q7KN62 R-DME-3371511 HSF1 activation XP_046661916.1 Q7KN62 R-DME-3371556 Cellular response to heat stress XP_046661916.1 Q7KN62 R-DME-382551 Transport of small molecules XP_046661916.1 Q7KN62 R-DME-382556 ABC-family protein mediated transport XP_046661916.1 Q7KN62 R-DME-392499 Metabolism of proteins XP_046661916.1 Q7KN62 R-DME-446203 Asparagine N-linked glycosylation XP_046661916.1 Q7KN62 R-DME-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle XP_046661916.1 Q7KN62 R-DME-5358346 Hedgehog ligand biogenesis XP_046661916.1 Q7KN62 R-DME-5358351 Signaling by Hedgehog XP_046661916.1 Q7KN62 R-DME-5688426 Deubiquitination XP_046661916.1 Q7KN62 R-DME-5689896 Ovarian tumor domain proteases XP_046661916.1 Q7KN62 R-DME-597592 Post-translational protein modification XP_046661916.1 Q7KN62 R-DME-6798695 Neutrophil degranulation XP_046661916.1 Q7KN62 R-DME-73893 DNA Damage Bypass XP_046661916.1 Q7KN62 R-DME-73894 DNA Repair XP_046661916.1 Q7KN62 R-DME-8951664 Neddylation XP_046661916.1 Q7KN62 R-DME-8953897 Cellular responses to stimuli XP_046661916.1 Q7KN62 R-DME-9012999 RHO GTPase cycle XP_046661916.1 Q7KN62 R-DME-9013407 RHOH GTPase cycle XP_046661916.1 Q7KN62 R-DME-9711123 Cellular response to chemical stress XP_046661916.1 Q7KN62 R-DME-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 XP_046661916.1 Q7KN62 R-DME-9755511 KEAP1-NFE2L2 pathway XP_046667353.1 Q7PLC7 R-DME-392499 Metabolism of proteins XP_046667353.1 Q7PLC7 R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein XP_046667353.1 Q7PLC7 R-DME-446203 Asparagine N-linked glycosylation XP_046667353.1 Q7PLC7 R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine XP_046667353.1 Q7PLC7 R-DME-446219 Synthesis of substrates in N-glycan biosythesis XP_046667353.1 Q7PLC7 R-DME-597592 Post-translational protein modification XP_046669747.1 Q9VAQ0 R-DME-1227986 Signaling by ERBB2 XP_046669747.1 Q9VAQ0 R-DME-1280218 Adaptive Immune System XP_046669747.1 Q9VAQ0 R-DME-162582 Signal Transduction XP_046669747.1 Q9VAQ0 R-DME-168256 Immune System XP_046669747.1 Q9VAQ0 R-DME-392499 Metabolism of proteins XP_046669747.1 Q9VAQ0 R-DME-597592 Post-translational protein modification XP_046669747.1 Q9VAQ0 R-DME-8863795 Downregulation of ERBB2 signaling XP_046669747.1 Q9VAQ0 R-DME-8951664 Neddylation XP_046669747.1 Q9VAQ0 R-DME-9006934 Signaling by Receptor Tyrosine Kinases XP_046669747.1 Q9VAQ0 R-DME-983168 Antigen processing: Ubiquitination & Proteasome degradation XP_046669747.1 Q9VAQ0 R-DME-983169 Class I MHC mediated antigen processing & presentation XP_046659025.1 O62609 R-DME-1181150 Signaling by NODAL XP_046659025.1 O62609 R-DME-1266738 Developmental Biology XP_046659025.1 O62609 R-DME-1502540 Signaling by Activin XP_046659025.1 O62609 R-DME-162582 Signal Transduction XP_046659025.1 O62609 R-DME-170834 Signaling by TGF-beta Receptor Complex XP_046659025.1 O62609 R-DME-201451 Signaling by BMP XP_046659025.1 O62609 R-DME-212436 Generic Transcription Pathway XP_046659025.1 O62609 R-DME-2173789 TGF-beta receptor signaling activates SMADs XP_046659025.1 O62609 R-DME-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer XP_046659025.1 O62609 R-DME-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity XP_046659025.1 O62609 R-DME-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription XP_046659025.1 O62609 R-DME-392499 Metabolism of proteins XP_046659025.1 O62609 R-DME-5688426 Deubiquitination XP_046659025.1 O62609 R-DME-5689880 Ub-specific processing proteases XP_046659025.1 O62609 R-DME-597592 Post-translational protein modification XP_046659025.1 O62609 R-DME-73857 RNA Polymerase II Transcription XP_046659025.1 O62609 R-DME-74160 Gene expression (Transcription) XP_046659025.1 O62609 R-DME-8878159 Transcriptional regulation by RUNX3 XP_046659025.1 O62609 R-DME-8878166 Transcriptional regulation by RUNX2 XP_046659025.1 O62609 R-DME-8941326 RUNX2 regulates bone development XP_046659025.1 O62609 R-DME-8941855 RUNX3 regulates CDKN1A transcription XP_046659025.1 O62609 R-DME-9006936 Signaling by TGFB family members XP_046659025.1 O62609 R-DME-9614085 FOXO-mediated transcription XP_046659025.1 O62609 R-DME-9617828 FOXO-mediated transcription of cell cycle genes XP_046675018.1 A1ZAK1 R-DME-6807505 RNA polymerase II transcribes snRNA genes XP_046675018.1 A1ZAK1 R-DME-73857 RNA Polymerase II Transcription XP_046675018.1 A1ZAK1 R-DME-74160 Gene expression (Transcription) XP_046678125.1 Q9VVL7 R-DME-1428517 Aerobic respiration and respiratory electron transport XP_046678125.1 Q9VVL7 R-DME-1430728 Metabolism XP_046678125.1 Q9VVL7 R-DME-162582 Signal Transduction XP_046678125.1 Q9VVL7 R-DME-204174 Regulation of pyruvate dehydrogenase (PDH) complex XP_046678125.1 Q9VVL7 R-DME-389661 Glyoxylate metabolism and glycine degradation XP_046678125.1 Q9VVL7 R-DME-392499 Metabolism of proteins XP_046678125.1 Q9VVL7 R-DME-5362517 Signaling by Retinoic Acid XP_046678125.1 Q9VVL7 R-DME-6783984 Glycine degradation XP_046678125.1 Q9VVL7 R-DME-70268 Pyruvate metabolism XP_046678125.1 Q9VVL7 R-DME-70895 Branched-chain amino acid catabolism XP_046678125.1 Q9VVL7 R-DME-71064 Lysine catabolism XP_046678125.1 Q9VVL7 R-DME-71291 Metabolism of amino acids and derivatives XP_046678125.1 Q9VVL7 R-DME-71403 Citric acid cycle (TCA cycle) XP_046678125.1 Q9VVL7 R-DME-9006931 Signaling by Nuclear Receptors XP_046678125.1 Q9VVL7 R-DME-9837999 Mitochondrial protein degradation XP_046678125.1 Q9VVL7 R-DME-9853506 OGDH complex synthesizes succinyl-CoA from 2-OG XP_046678125.1 Q9VVL7 R-DME-9858328 OADH complex synthesizes glutaryl-CoA from 2-OA XP_046678125.1 Q9VVL7 R-DME-9859138 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV XP_046678125.1 Q9VVL7 R-DME-9861559 PDH complex synthesizes acetyl-CoA from PYR XP_046678125.1 Q9VVL7 R-DME-9861718 Regulation of pyruvate metabolism