Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_049819873.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049822620.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049821686.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049817328.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019865445.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_049826707.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019867827.2	33	Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453	"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response"
XP_019868739.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_019865598.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism"
XP_019877486.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019881850.1	6	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
XP_019866024.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_019864559.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism"
XP_019873354.2	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_019870089.1	7	Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism"
XP_019869549.2	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_049826420.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049818437.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821950.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_019876023.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_019867614.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_019874936.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049819925.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049817410.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019873268.1	9	MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;KEGG: 00230+1.7.1.7;MetaCyc: PWY-7221;Reactome: R-HSA-74217;KEGG: 00230+1.1.1.205	"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine salvage";"Purine metabolism"
XP_049817848.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866211.1	4	MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Oxidative phosphorylation"
XP_049819438.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236	"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Neddylation";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049819181.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049819478.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_019867760.1	182	Reactome: R-HSA-9020702;Reactome: R-HSA-72695;Reactome: R-HSA-5696395;Reactome: R-HSA-5676590;Reactome: R-HSA-168638;Reactome: R-HSA-205043;Reactome: R-HSA-182971;Reactome: R-HSA-69017;Reactome: R-HSA-9646399;Reactome: R-HSA-5655862;Reactome: R-HSA-3322077;Reactome: R-HSA-5687128;Reactome: R-HSA-937039;Reactome: R-HSA-8876493;Reactome: R-HSA-2173795;Reactome: R-HSA-110320;Reactome: R-HSA-1236974;Reactome: R-HSA-937042;Reactome: R-HSA-9013973;Reactome: R-HSA-6782210;Reactome: R-HSA-9013507;Reactome: R-HSA-5610785;Reactome: R-HSA-9014325;Reactome: R-HSA-72764;Reactome: R-HSA-917937;Reactome: R-HSA-69601;Reactome: R-HSA-179409;Reactome: R-HSA-5684264;Reactome: R-HSA-937072;Reactome: R-HSA-180585;Reactome: R-HSA-2408557;Reactome: R-HSA-2122948;Reactome: R-HSA-1169091;Reactome: R-HSA-5357905;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;Reactome: R-HSA-5654732;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-8852276;Reactome: R-HSA-917729;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-174048;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5654733;Reactome: R-HSA-5668541;Reactome: R-HSA-4641263;Reactome: R-HSA-975163;Reactome: R-HSA-5658442;Reactome: R-HSA-2894862;Reactome: R-HSA-912631;Reactome: R-HSA-2565942;Reactome: R-HSA-5654726;Reactome: R-HSA-983168;Reactome: R-HSA-6807004;Reactome: R-HSA-174084;Reactome: R-HSA-1253288;Reactome: R-HSA-2871837;Reactome: R-HSA-1236382;Reactome: R-HSA-9633012;Reactome: R-HSA-174113;Reactome: R-HSA-6781827;Reactome: R-HSA-180534;Reactome: R-HSA-69541;Reactome: R-HSA-9613829;Reactome: R-HSA-4641257;Reactome: R-HSA-2173788;Reactome: R-HSA-2672351;Reactome: R-HSA-1295596;Reactome: R-HSA-2644606;Reactome: R-HSA-8866654;Reactome: R-HSA-9637628;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-2559580;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-5689901;Reactome: R-HSA-1358803;Reactome: R-HSA-156827;Reactome: R-HSA-5689877;Reactome: R-HSA-72702;Reactome: R-HSA-162588;Reactome: R-HSA-5654727;Reactome: R-HSA-69481;Reactome: R-HSA-2122947;Reactome: R-HSA-175474;Reactome: R-HSA-975957;Reactome: R-HSA-9645460;Reactome: R-HSA-5689896;Reactome: R-HSA-75815;Reactome: R-HSA-2691232;Reactome: R-HSA-209560;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-72706;Reactome: R-HSA-5610780;Reactome: R-HSA-110314;Reactome: R-HSA-201681;Reactome: R-HSA-6791226;Reactome: R-HSA-8875360;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8849469;Reactome: R-HSA-8856828;Reactome: R-HSA-5362768;Reactome: R-HSA-8863795;Reactome: R-HSA-1169408;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-2559585;Reactome: R-HSA-72649;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-8939236;Reactome: R-HSA-5696394;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-936964;Reactome: R-HSA-8854050;Reactome: R-HSA-5696400;Reactome: R-HSA-2173796;Reactome: R-HSA-6781823;Reactome: R-HSA-209543;Reactome: R-HSA-532668;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-2979096;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-8939902;Reactome: R-HSA-72689;Reactome: R-HSA-168928;Reactome: R-HSA-174490;Reactome: R-HSA-4608870;Reactome: R-HSA-901032;Reactome: R-HSA-168927;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-5675482;Reactome: R-HSA-5205685;Reactome: R-HSA-450321;Reactome: R-HSA-110312;Reactome: R-HSA-975110;Reactome: R-HSA-2173791;Reactome: R-HSA-6782135;Reactome: R-HSA-69231;Reactome: R-HSA-5689603;Reactome: R-HSA-6783310;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5656121;Reactome: R-HSA-9615710;Reactome: R-HSA-5685942;Reactome: R-HSA-937041;Reactome: R-HSA-975956;Reactome: R-HSA-450302;Reactome: R-HSA-5675221;Reactome: R-HSA-6804757;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-2559582;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-192823;Reactome: R-HSA-5678895;Reactome: R-HSA-3785653;Reactome: R-HSA-977225;Reactome: R-HSA-8941858;Reactome: R-HSA-3134975;Reactome: R-HSA-975144;Reactome: R-HSA-9033241;Reactome: R-HSA-68827;Reactome: R-HSA-202424	"Interleukin-1 signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of Incision Complex in GG-NER";"NIK-->noncanonical NF-kB signaling";"NOD1/2 Signaling Pathway";"NRIF signals cell death from the nucleus";"EGFR downregulation";"CDK-mediated phosphorylation and removal of Cdc6";"Aggrephagy";"Translesion synthesis by POLK";"Glycogen synthesis";"MAPK6/MAPK4 signaling";"IRAK1 recruits IKK complex";"InlA-mediated entry of Listeria monocytogenes into host cells";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Translesion Synthesis by POLH";"ER-Phagosome pathway";"IRAK2 mediated activation of TAK1 complex";"TICAM1-dependent activation of IRF3/IRF7";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"GLI3 is processed to GLI3R by the proteasome";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Eukaryotic Translation Termination";"Iron uptake and transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC-Cdc20 mediated degradation of Nek2A";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Vif-mediated degradation of APOBEC3G";"Selenocysteine synthesis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Activation of NF-kappaB in B cells";"Regulation of TNFR1 signaling";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of FGFR3 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Negative regulation of FGFR4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of FZD by ubiquitination";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of RAS by GAPs";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of signaling by CBL";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of FGFR1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of MET activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downregulation of ERBB4 signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SCF-beta-TrCP mediated degradation of Emi1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Vpu mediated degradation of CD4";"Stabilization of p53";"Chaperone Mediated Autophagy";"Degradation of AXIN";"Downregulation of TGF-beta receptor signaling";"Stimuli-sensing channels";"Spry regulation of FGF signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"Modulation by Mtb of host immune system";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxidative Stress Induced Senescence";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Metalloprotease DUBs";"Downregulation of ERBB2:ERBB3 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Josephin domain DUBs";"Ribosomal scanning and start codon recognition";"Budding and maturation of HIV virion";"Negative regulation of FGFR2 signaling";"G2/M Checkpoints";"NOTCH1 Intracellular Domain Regulates Transcription";"Assembly Of The HIV Virion";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Alpha-protein kinase 1 signaling pathway";"Ovarian tumor domain proteases";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NF-kB is activated and signals survival";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Degradation of GLI1 by the proteasome";"Recognition of DNA damage by PCNA-containing replication complex";"TCF dependent signaling in response to WNT";"Major pathway of rRNA processing in the nucleolus and cytosol";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Clathrin-mediated endocytosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2 signaling";"ISG15 antiviral mechanism";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Oncogene Induced Senescence";"Translation initiation complex formation";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage Recognition in GG-NER";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dual Incision in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of TC-NER Pre-Incision Complex";"p75NTR recruits signalling complexes";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX2 expression and activity";"Formation of a pool of free 40S subunits";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Membrane binding and targetting of GAG proteins";"Asymmetric localization of PCP proteins";"ER Quality Control Compartment (ERQC)";"TICAM1, RIP1-mediated IKK complex recruitment";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Regulation of necroptotic cell death";"Pink/Parkin Mediated Mitophagy";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Translesion synthesis by REV1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Dual incision in TC-NER";"Cyclin D associated events in G1";"UCH proteinases";"Fanconi Anemia Pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Translesion synthesis by POLI";"Late endosomal microautophagy";"HDR through Homologous Recombination (HRR)";"IKK complex recruitment mediated by RIP1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"activated TAK1 mediates p38 MAPK activation";"Negative regulation of MAPK pathway";"Regulation of TP53 Degradation";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Viral mRNA Translation";"Defective CFTR causes cystic fibrosis";"Myoclonic epilepsy of Lafora";"Amyloid fiber formation";"Regulation of RUNX3 expression and activity";"Regulation of innate immune responses to cytosolic DNA";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Peroxisomal protein import";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling"
XP_019878769.2	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_019867459.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049823782.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049818238.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-198323	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol"
XP_019864874.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_019865465.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019878661.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049819567.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_049822561.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_049824257.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019876944.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_019871721.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_049819685.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019866634.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_019871960.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_019869346.2	22	Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway"
XP_019880820.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_019876278.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019877156.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049822464.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019872898.1	17	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_019867817.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-191859	"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"snRNP Assembly"
XP_049821821.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_019871467.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049825612.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019866657.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_049818761.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019866322.1	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_019878018.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049822858.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_019864871.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
XP_019871864.2	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_019877771.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049817020.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_019864778.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_019866771.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-983168	"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Neddylation";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818796.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049821682.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_019881283.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019872746.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049817682.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049818042.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049821948.1	3	Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080	"PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)"
XP_049826376.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049817523.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_019878467.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019879334.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_019874484.2	14	Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2"
XP_019869215.2	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049817998.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019877409.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_019866982.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_019867818.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049823825.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019866960.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-165054	"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA"
XP_049819420.1	14	KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE"
XP_019864661.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_019870079.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019869220.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049822821.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049825385.1	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_019872837.1	5	KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_019869489.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821105.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_019881378.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_019875945.2	7	KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36	"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_019869104.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_019865774.2	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_049821825.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_019864821.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-525793	"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Myogenesis"
XP_019874293.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019869575.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019881842.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_019876896.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_019866377.2	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_019874024.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019868090.1	7	Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-7219;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_019864589.1	11	Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-2871796;Reactome: R-HSA-2559582;Reactome: R-HSA-8862803;Reactome: R-HSA-8943724;Reactome: R-HSA-1912408;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-450341	"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FCERI mediated MAPK activation";"Senescence-Associated Secretory Phenotype (SASP)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Regulation of PTEN gene transcription";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Activation of the AP-1 family of transcription factors"
XP_049826759.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049818950.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_019867456.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049818178.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049825505.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-426496	"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs"
XP_019869817.2	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_019866219.1	30	Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-2644606;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546	"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Neddylation";"Prolactin receptor signaling"
XP_019869132.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019870037.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_019879919.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049821929.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019870383.2	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_019872929.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_019872908.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049825874.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049818904.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_019872138.2	6	KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_019868515.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049818869.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019869834.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_019869949.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049819826.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019874385.1	9	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol"
XP_019871205.2	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Relaxin signaling pathway";"Thermogenesis"
XP_049817232.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049821325.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019867073.2	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_019869292.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049816950.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019867049.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019867283.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049817900.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_019877012.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_019875222.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049824612.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019865491.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_019865557.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_019870287.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019873636.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_019868818.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019867215.2	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_019865771.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_019868130.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019872117.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_049820547.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049825127.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049825651.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_019876504.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866544.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049818874.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_019870862.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_019872034.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_019872289.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049824080.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_019877601.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_019869986.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_019869348.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_019871104.2	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_019869174.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049819523.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019872685.1	8	MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism"
XP_019865865.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019874463.2	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049825472.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_019866508.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_019880891.2	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_019866844.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049822108.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049822365.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_019873992.2	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_019880035.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_019878278.2	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_019866579.2	11	KEGG: 00250+6.3.5.5;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;MetaCyc: PWY-5154;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791	"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis III"
XP_049822571.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_019871698.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049822670.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049820083.1	5	KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4	"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation"
XP_019869097.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049818658.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049825027.1	10	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Relaxin signaling pathway";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"mTOR signaling pathway";"Human papillomavirus infection"
XP_019873541.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817375.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_019866772.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049823213.1	32	Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_049823387.1	4	MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
XP_049817846.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821936.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_019865606.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049826458.1	11	Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801	"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD"
XP_049819055.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_019866168.1	30	Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1170546;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-2644607;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-400253	"Neddylation";"Orc1 removal from chromatin";"Prolactin receptor signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock"
XP_019881843.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_019880467.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_019873074.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019878358.2	32	Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-75955	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation"
XP_049821399.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049818022.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207	"Regulation of the apoptosome activity";"Neutrophil degranulation";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_019877707.2	9	Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_019868056.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019870092.2	14	Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782	"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis"
XP_049824060.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019873823.2	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049823577.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049824252.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049820652.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_019868054.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019865850.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_019876965.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_019878279.2	17	Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-9616222;Reactome: R-HSA-8953750;Reactome: R-HSA-111448;Reactome: R-HSA-69202;Reactome: R-HSA-139915;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114;Reactome: R-HSA-2559585;Reactome: R-HSA-69231	"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional regulation of granulopoiesis";"Transcriptional Regulation by E2F6";"Activation of NOXA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Oncogene Induced Senescence";"Cyclin D associated events in G1"
XP_049818422.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_019870036.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049824061.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019869241.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049820172.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049821207.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019864701.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_049823503.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049821266.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049826601.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019873349.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_019867660.2	6	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_049819088.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_019870297.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019873239.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_019875265.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_019871394.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049820281.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_019873318.2	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_019877543.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049821381.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines"
XP_049820571.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_019871741.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_019880995.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019870999.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN"
XP_049819845.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049820916.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049823896.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049826046.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019881572.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_019871696.1	10	MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism"
XP_049819378.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736	"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors"
XP_019865198.2	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049826478.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019875632.2	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049825276.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_019865148.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019868545.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_049821394.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019866693.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_019877623.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019871530.2	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_019881698.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019880816.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_019869925.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049826622.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019872349.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019873231.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019867017.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049825683.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_019881177.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"Macroautophagy"
XP_019878602.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049820376.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_019880755.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049820288.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019872672.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049819560.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_049824498.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019873353.2	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049817059.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019865252.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_019866077.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I"
XP_049820605.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019876753.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049824168.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_019868886.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019873376.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049817632.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049820232.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019876069.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019871515.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019874190.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_019876614.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019867112.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019865003.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_019874650.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019880539.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_019869985.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_019872236.2	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049821194.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049821632.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5545619	"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_049819305.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049818551.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019875658.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049820219.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Neutrophil degranulation"
XP_019880270.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_019865270.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_019873141.2	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_019874377.2	13	KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-4061;MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;Reactome: R-HSA-196836;MetaCyc: PWY-7112	"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification"
XP_019877096.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049824076.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_019868268.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019866595.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019871521.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019880902.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_019874692.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-75893;Reactome: R-HSA-1251985	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Signaling by EGFR";"TNF signaling";"Nuclear signaling by ERBB4"
XP_049821101.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818390.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_019872324.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019871326.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis"
XP_049825048.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821027.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019875365.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_019871520.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632	"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Meiotic synapsis"
XP_049820442.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_019865061.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-180746	"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Nuclear import of Rev protein"
XP_019870658.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_049822702.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019871200.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_019865500.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_019878202.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019871076.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019868257.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_019876762.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_019867227.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_019868287.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019870015.2	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296	"HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome"
XP_019869844.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis"
XP_019871693.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11	"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism"
XP_049826117.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049819579.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049825863.1	13	Reactome: R-HSA-9649948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952	"Signaling downstream of RAS mutants";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions"
XP_019874248.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6804756	"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation"
XP_019879597.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_049817161.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_019875079.2	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6952	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerophosphodiester degradation"
XP_019865988.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_049821336.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402	"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex"
XP_019881087.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049820921.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870	"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_049825980.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_019865833.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_019874570.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_019868034.2	9	KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00960+2.6.1.5	"Cysteine and methionine metabolism";"Tyrosine catabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_049824868.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_049824007.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019874701.2	5	Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
XP_019875871.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_019867217.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019877838.2	52	Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-5617472	"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049819962.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049820279.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_019880476.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019868514.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_019872425.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019864994.2	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019864819.2	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_019879625.2	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_049817989.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049819253.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019881093.2	10	KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-7003	"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol"
XP_049820088.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049825812.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049822244.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049819375.1	5	KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_019864845.1	11	MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675	"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)"
XP_019865597.2	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism"
XP_019877621.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_019880577.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_019881973.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049824826.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_019873626.1	24	Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-163359	"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation"
XP_019868843.2	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_019873582.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019876054.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817434.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049824862.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019881414.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_019865521.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049817481.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049826267.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_019872638.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019878374.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"O-linked glycosylation"
XP_049820285.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_019868106.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019866224.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019874556.1	9	MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I"
XP_019868125.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019872332.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019872149.2	8	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_019869273.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019871849.2	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-114608	"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation"
XP_019873035.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_019870268.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_019875200.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-416993	"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors"
XP_049818497.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049817448.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40	"Glycolysis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
XP_049822957.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_019874974.1	14	Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Macroautophagy"
XP_019876120.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049821968.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049818682.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019874176.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019876718.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049820341.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019866930.1	10	MetaCyc: PWY-6536;Reactome: R-HSA-916853;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6537	"4-aminobutanoate degradation III";"Degradation of GABA";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"4-aminobutanoate degradation I";"Butanoate metabolism";"4-aminobutanoate degradation II"
XP_049817471.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_019875087.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049817698.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328	"D-galactose detoxification";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_019867277.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019865546.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049823625.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049824900.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019869600.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_049818859.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049821471.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019865555.2	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_019873381.2	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_019873897.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049819565.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_019866794.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276	"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Degradation of DVL";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_019868424.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049822340.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019873130.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049821040.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019877241.2	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049817414.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049820402.1	14	MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409	"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_019867840.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049824961.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019865911.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049820696.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_049821558.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049820161.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049825989.1	9	Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6146;Reactome: R-HSA-3371599	"Gluconeogenesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_019870072.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049826466.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_019871495.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049823653.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049817342.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_019867968.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_019866671.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049823048.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_019866373.2	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)"
XP_019873857.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049820283.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049821999.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis"
XP_019870286.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_019881772.2	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_019865159.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049821402.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019877295.2	16	Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-983168	"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019868982.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019869192.2	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_019877005.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_019873975.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019867282.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019874431.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049819867.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019871314.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049820080.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049823270.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868500.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049818467.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_019870544.2	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_049824338.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019873493.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_019872173.2	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_019879638.1	6	MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_019873931.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_019875235.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049817656.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019873780.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991	"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions"
XP_019869665.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049820166.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019875009.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019865478.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019866048.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_019877450.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_019873896.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_019865703.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049821265.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_019871879.1	7	Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049823729.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_019872280.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049819458.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049821339.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333	"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated"
XP_049818446.1	11	Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642	"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling"
XP_049825581.1	6	MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7077	"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation"
XP_019875341.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049825499.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_019865787.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019877619.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049820750.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049818110.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019873633.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_019870913.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019871594.2	8	Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Neutrophil degranulation"
XP_049823767.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019876675.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049826575.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_019866295.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049821199.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_019875556.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_019880483.2	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_019875602.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019869997.1	33	MetaCyc: PWY-6342;MetaCyc: PWY-6871;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5076;MetaCyc: PWY-6587;MetaCyc: PWY-6802;KEGG: 00350+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-7118;MetaCyc: PWY-3162;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;Reactome: R-HSA-71384;MetaCyc: PWY-6333;MetaCyc: PWY-5057;MetaCyc: PWY-7798;KEGG: 00626+1.1.1.1;KEGG: 00982+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5082;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-6313;MetaCyc: PWY-7111;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-5486;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5480	"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(S)-propane-1,2-diol degradation";"L-leucine degradation III";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis";"Tyrosine metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Chitin degradation to ethanol";"L-tryptophan degradation V (side chain pathway)";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Ethanol oxidation";"Acetaldehyde biosynthesis I";"L-valine degradation II";"Protein S-nitrosylation and denitrosylation";"Naphthalene degradation";"Drug metabolism - cytochrome P450";"Methane metabolism";"L-methionine degradation III";"Retinol metabolism";"L-isoleucine degradation II";"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol II";"Fatty acid degradation";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol I"
XP_019867298.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_019867567.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049824220.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049823260.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049826488.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049818439.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049818530.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049826499.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049822486.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_049822241.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019865283.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_019880352.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049821983.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_019868971.2	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049824636.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049818257.1	13	KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_019870166.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_019875985.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049819857.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_019872835.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049824566.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_049821985.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Kinesins";"Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019869945.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019872628.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019865311.2	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_019873738.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_019871840.2	9	Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355	"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction"
XP_019877213.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6	"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism"
XP_019872849.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049826572.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821138.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049825422.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038	"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"LDL clearance"
XP_049823012.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_019866528.2	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049825897.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019872122.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019873198.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049824455.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_019872918.2	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_019881262.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_019874059.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_019875784.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells"
XP_019879452.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_019878449.2	15	Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519	"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression"
XP_019869072.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049826099.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019865786.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049826638.1	7	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-140837	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation"
XP_019874573.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_019867303.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049824550.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_019881682.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019879535.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_019880948.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019881344.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_049822370.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_019864859.1	6	Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049821039.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6142	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Purine metabolism";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_019875306.1	19	Reactome: R-HSA-163765;MetaCyc: PWY-5913;KEGG: 00720+2.3.3.8;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5392	"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II"
XP_049820033.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019876298.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019873103.2	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_019873856.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_019871643.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049819477.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_019869835.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049820469.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049818247.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_049819239.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049824973.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production"
XP_049819811.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019876914.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817095.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_019866497.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_019872282.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_019880267.2	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_019865203.2	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019870052.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049825252.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019869980.2	6	KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_019873258.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019867984.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049820565.1	7	MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism"
XP_049825370.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049818690.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019871184.2	27	Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-1169408	"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism"
XP_019869111.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049821956.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans"
XP_049826616.1	5	MetaCyc: PWY-6891;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
XP_019875008.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019870819.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019866183.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_019869574.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019870374.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_019875178.2	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049822652.1	5	KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)"
XP_019871335.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-0;MetaCyc: PWY-6117	"Arginine and proline metabolism";"Putrescine degradation III";"Spermine and spermidine degradation I"
XP_019872791.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_019880274.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019870354.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_019872110.2	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Oncogene Induced Senescence"
XP_019869699.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049823367.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019865461.2	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049820246.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_019879462.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_049825633.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_019866526.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_019864883.2	7	MetaCyc: PWY-4984;Reactome: R-HSA-70635;MetaCyc: PWY-46;MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1	"Urea cycle";"Urea cycle";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine and proline metabolism";"Arginine biosynthesis"
XP_019865209.2	6	KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52	"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Methane metabolism";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism"
XP_049818671.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019871074.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049825733.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_019878537.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019881551.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_019881223.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049819038.1	10	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5576893;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5576890;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6802952;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Phase 2 - plateau phase";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Phase 3 - rapid repolarisation";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Signaling by BRAF and RAF fusions";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019872938.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019879859.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019866457.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_019868272.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049823554.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049819592.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_019865136.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049822128.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019877376.2	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_049822385.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_019872239.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_049817896.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_019864911.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049820188.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_019869156.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049823269.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019871018.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_019874521.2	6	MetaCyc: PWY-7285;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-8868766	"Methylwyosine biosynthesis";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"rRNA processing in the mitochondrion"
XP_019874693.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-5362798	"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"TNF signaling";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Release of Hh-Np from the secreting cell"
XP_049826729.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_019871857.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_019877013.1	18	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019880306.2	19	Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Chylomicron assembly";"VLDL assembly";"Chylomicron remodeling";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors"
XP_049825557.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_019865855.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858	"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity"
XP_049823541.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_049817272.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019876284.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_019865398.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_019876853.2	8	Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_019864613.2	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049818102.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049826584.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-425986	"Stimuli-sensing channels";"Sodium/Proton exchangers"
XP_049819130.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019879670.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_049823763.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019872097.2	17	KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Relaxin signaling pathway";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019869458.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_019874472.2	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_019877405.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049822320.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049819045.1	10	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5576893;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6802952;Reactome: R-HSA-380270;Reactome: R-HSA-5576890;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Phase 2 - plateau phase";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Signaling by BRAF and RAF fusions";"Recruitment of mitotic centrosome proteins and complexes";"Phase 3 - rapid repolarisation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049822195.1	17	KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-1622;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37	"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)"
XP_049821250.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019877752.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019872863.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_019877539.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019870919.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_019874875.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019868896.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_019865134.2	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_019865634.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_019877011.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_019870591.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049826783.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049821824.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_019875832.2	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019864782.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049819594.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049818465.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019870033.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049817295.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019873846.2	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_019870674.2	12	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73863	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination"
XP_049826364.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_019876872.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_049819640.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049821103.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019866088.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019868792.1	6	Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1	"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_019869266.2	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_019870652.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_019875283.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049821716.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_019868721.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049818473.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049824258.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049825680.1	3	MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_019867397.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_019877044.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049824634.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019870401.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_019875628.1	3	Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_019875415.2	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_049824504.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019865230.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049819188.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049819820.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019876599.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_049821748.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049817851.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_019866241.1	10	Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-9627069	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity"
XP_019867732.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049826094.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019864703.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_019881587.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019881939.1	1	Reactome: R-HSA-6804115	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049817402.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-3214858;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114	"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_019867045.2	5	Reactome: R-HSA-5362768;Reactome: R-HSA-381038;Reactome: R-HSA-5358346;Reactome: R-HSA-901032;MetaCyc: PWY-7511	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination"
XP_019878524.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049818334.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019875635.1	9	MetaCyc: PWY-7385;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-5667	"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_049823138.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049823251.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049824282.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_049826404.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049821029.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049824339.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049823950.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019881962.2	6	KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049825741.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_019873509.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-8963896;Reactome: R-HSA-5610783;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-9634600;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610780;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163358;Reactome: R-HSA-422356;Reactome: R-HSA-5610785;Reactome: R-HSA-983231;Reactome: R-HSA-163560;Reactome: R-HSA-5610787;Reactome: R-HSA-111931;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-8853659;Reactome: R-HSA-5621575;Reactome: R-HSA-5687128	"Vasopressin regulates renal water homeostasis via Aquaporins";"HDL assembly";"Degradation of GLI2 by the proteasome";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI1 by the proteasome";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"PKA-mediated phosphorylation of key metabolic factors";"Regulation of insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production";"Triglyceride catabolism";"Hedgehog 'off' state";"PKA-mediated phosphorylation of CREB";"Rap1 signalling";"PKA activation";"RET signaling";"CD209 (DC-SIGN) signaling";"MAPK6/MAPK4 signaling"
XP_019867421.2	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_019866386.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019874766.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049821162.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049824853.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2"
XP_049822580.1	30	Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-917937	"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"Neddylation";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport"
XP_049821201.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049818591.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_019877741.2	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049818825.1	12	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Rho GTPase cycle";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_019877339.2	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_019873865.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_019878420.2	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_019872194.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049825933.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_019876306.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049817165.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692	"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity"
XP_019875742.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019877839.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5685939	"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)"
XP_049820708.1	5	MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_049817911.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_019866787.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049823952.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049819260.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049825769.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049826369.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_019881875.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049817325.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049820261.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019876612.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_019878226.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049817928.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049820776.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_019873454.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049817289.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019864557.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_019873329.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_019864912.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049819590.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019871816.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_019875719.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019872634.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_019867914.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019866766.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049819201.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049820892.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_019867338.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_019871722.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049817969.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049818746.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486	"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis"
XP_049824174.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019874229.2	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-8060	"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I"
XP_019871789.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049822983.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049819242.1	18	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049819540.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019867477.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_019878131.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019868835.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049817408.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019870083.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019866504.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049821054.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_019876334.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019870859.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049826218.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_019870088.2	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_019881335.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_019877098.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_019869603.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049819161.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128	"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ABC-family proteins mediated transport";"Neddylation";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling"
XP_049826635.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049817907.1	17	Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167238;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;KEGG: 05235+3.1.3.16	"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049819848.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049821195.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049823349.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019865448.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049823957.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019874503.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049821459.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019864707.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_049825051.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_019873314.2	6	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_049826537.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_019864941.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019870647.2	13	KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2160916	"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation"
XP_019872196.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049818528.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_019869859.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism"
XP_019881720.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_019867347.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049825936.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019873384.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Downstream TCR signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Neddylation";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_049826748.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019870750.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"Transcription of the HIV genome";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049818767.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_049821912.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_049823562.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019878880.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019871533.1	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394	"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II"
XP_019870569.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049824616.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019871842.2	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695	"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Neutrophil degranulation"
XP_019875218.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019874925.1	7	Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-381033	"PERK regulates gene expression";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones"
XP_019874569.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_019866290.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049824162.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019872017.2	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049819566.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049818974.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049818823.1	12	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Rho GTPase cycle";"Human papillomavirus infection";"mTOR signaling pathway";"NRAGE signals death through JNK"
XP_049819535.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049817271.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019870013.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019864671.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_019869162.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049825473.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_019865856.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-180534	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Neddylation";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Downstream TCR signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4"
XP_049820306.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049824072.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_019870906.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"G2/M Checkpoints";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_019873534.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049824442.1	18	Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Linoleic acid metabolism"
XP_049821470.1	30	Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2644607;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590	"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"Orc1 removal from chromatin";"Neddylation";"Circadian Clock";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling"
XP_049818963.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019872811.2	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_019867686.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_019877036.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049822495.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049824627.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_019869250.2	3	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation"
XP_049818790.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019864706.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_049821393.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049825439.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_019881612.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049817685.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049826455.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019867369.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049822501.1	5	MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20	"Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes"
XP_049822106.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_019873616.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019871077.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049820245.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_049826386.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019870223.2	16	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation"
XP_019866674.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936440	"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling"
XP_019871479.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import"
XP_019871016.2	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_049822732.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049823239.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_019871695.1	10	KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042	"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)"
XP_019877765.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019867062.2	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_049817799.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_019878190.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019870127.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_019872072.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820167.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049822576.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019866381.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_049824663.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019877634.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049821900.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049820615.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019881359.1	8	KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Synthesis of PG"
XP_019865672.2	7	Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049817318.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019864548.2	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019881743.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
YP_009437734.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049821357.1	30	Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-2644606;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-2644607;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-5610785	"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Circadian Clock";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome"
XP_019867619.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878	"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport"
XP_019880968.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019868760.2	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism"
XP_049817331.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019870160.2	9	Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"snRNP Assembly";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019876908.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049824279.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019880140.2	2	Reactome: R-HSA-210745;Reactome: R-HSA-210746	"Regulation of gene expression in beta cells";"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"
XP_019873840.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_019881818.2	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_019867447.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049818441.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049820307.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_019870066.1	9	Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6146;Reactome: R-HSA-3371599	"Gluconeogenesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_049825378.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049824319.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049819837.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019872341.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049819321.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs"
XP_049823568.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019881365.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049818659.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_049826387.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049819749.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019872657.2	57	Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346	"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"G2/M Checkpoints";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis"
XP_019879860.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049821010.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_019873976.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049824978.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_019872592.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049824897.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019880493.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019881730.2	24	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors"
XP_049825748.1	5	MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
XP_019870026.2	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049819215.1	13	MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-2261;Reactome: R-HSA-156590	"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Glutathione conjugation"
XP_049823692.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_019876900.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_019880253.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_019871863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019876700.2	8	Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_049821379.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Interleukin-7 signaling"
XP_019867336.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019867856.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049818870.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_019880814.1	8	MetaCyc: PWY-6556;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7181;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage"
XP_049817633.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_019867588.2	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049826122.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049824093.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism"
XP_019875983.2	61	Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;MetaCyc: PWY-7803;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5689901;Reactome: R-HSA-180585;MetaCyc: PWY-6689;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-6784531;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-983168	"Regulation of RUNX3 expression and activity";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"G2/M Checkpoints";"Downstream TCR signaling";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Trna splicing II";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Metalloprotease DUBs";"Vif-mediated degradation of APOBEC3G";"Trna splicing I";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"tRNA processing in the nucleus";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019874758.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019875261.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019875807.2	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_049824762.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019870865.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_019873274.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019868428.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049824361.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049819440.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049826489.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019864997.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019881348.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_019877825.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_049821908.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_019880718.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049824100.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049819289.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-174430	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation"
XP_019877594.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049818177.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049824005.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049820391.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_019869071.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049817882.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019866376.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_049817484.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019878159.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_019870420.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_019878148.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_049820482.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019867268.2	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049820677.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_019877525.1	33	Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin D associated events in G1";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_049824430.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_019881702.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019867334.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049824511.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049823431.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019880382.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019864927.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019877770.2	40	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-72203	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA"
XP_019868499.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019872852.2	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_019873891.2	33	Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214	"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins"
XP_049825569.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-174430	"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation"
XP_019877629.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_019871934.2	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049822857.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_019866002.1	13	Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52	"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis"
XP_019867179.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_019880388.1	17	Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-202424;Reactome: R-HSA-9014325;Reactome: R-HSA-9645460;Reactome: R-HSA-4086398;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-450302	"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"Downstream TCR signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Ub-specific processing proteases";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation"
XP_049821286.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_019873165.2	14	Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862	"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK"
XP_049823908.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019869964.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_019867682.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823	"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"Transcription of the HIV genome";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex"
XP_049819514.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868123.2	7	Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23	"Pyrimidine biosynthesis";"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism"
XP_049820645.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_019867910.2	27	Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3371453	"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response"
XP_019878902.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_019870577.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_019867032.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019864827.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_019881487.2	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Neutrophil degranulation";"STAT6-mediated induction of chemokines"
XP_019866400.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019881318.2	11	Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049824723.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_019870190.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049821404.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049821961.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
YP_009437735.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049822259.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049821962.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019866872.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049824527.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049818017.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019864879.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_019874797.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049820747.1	14	KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453	"Sphingolipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Triglyceride biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Stigma estolide biosynthesis"
XP_019874812.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019870881.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_019865607.2	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_019867250.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_019868718.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049824357.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_019867630.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049822312.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019868210.2	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_019866328.2	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils"
XP_019877948.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049825957.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019873800.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049819741.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019869456.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_019870062.2	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049817677.1	57	Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562	"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)"
XP_019864563.2	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049817173.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence"
XP_049820638.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049819770.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019874477.2	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_019869819.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049820028.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_049821643.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049817023.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049818861.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019879419.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_019870347.1	8	Reactome: R-HSA-5683826;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179	"Surfactant metabolism";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I"
XP_019880272.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049821939.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049825811.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049824452.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism"
XP_019868420.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049823326.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_049824755.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019873598.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-983168	"Aggrephagy";"Josephin domain DUBs";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818089.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019876367.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome"
XP_019876824.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865370.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019864881.2	13	MetaCyc: PWY-5690;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2	"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)"
XP_019864798.2	8	Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex"
XP_019877618.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_019866012.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_049823150.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049818119.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049826349.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_019876621.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019879162.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_019869733.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049820032.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation"
XP_049823145.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019869712.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049822262.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019877681.2	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_019877926.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_019873423.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019879320.2	8	Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Oxidative phosphorylation";"Photosynthesis";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_019878118.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049822996.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019864989.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090	"Collagen degradation";"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures"
XP_019867388.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049818483.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049821164.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049820576.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818245.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_049821438.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017	"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6"
XP_049821782.1	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_019870939.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049824718.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_019879609.2	15	Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"G2/M DNA damage checkpoint"
XP_019865572.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_019877296.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049818580.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_019864993.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019876950.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_019868544.2	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_019865202.2	4	Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049821970.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_019873036.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_019869137.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019865245.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019880252.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_019881477.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049823366.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049819071.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049826702.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019872411.2	5	Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3	"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes"
XP_019876196.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_049821994.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins"
XP_049821287.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_019867339.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_019880829.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049819809.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049818410.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049820831.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_019877387.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019874576.2	19	MetaCyc: PWY-5392;Reactome: R-HSA-70263;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37	"Reductive TCA cycle II";"Gluconeogenesis";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism"
XP_049819879.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_019873860.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-6708;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-5855;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5870	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_019880375.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019878207.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049818032.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019867177.2	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
XP_019869775.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_019874960.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_019872061.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_019864689.2	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_019873102.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019874370.2	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_019878375.1	57	Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695	"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation"
XP_019881567.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019876874.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-69205	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription"
XP_019872963.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019871119.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_019880701.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019867198.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_019874572.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049826487.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019869031.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049818108.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049821377.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019873938.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019865282.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_019881284.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049819314.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_019873104.1	10	MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis"
XP_019876778.2	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049823154.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019873286.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019880447.2	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049822378.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019878020.2	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_019869401.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019874173.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019880562.1	8	Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;Reactome: R-HSA-6791055	"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
XP_019871757.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049825849.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019869637.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_019869918.2	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_019867739.2	1	Reactome: R-HSA-419771	"Opsins"
XP_019867543.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_019867627.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399	"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy"
XP_049820388.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_019874587.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049821037.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7218;Reactome: R-HSA-70171	"Purine metabolism";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis"
XP_019867599.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049824324.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049822494.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_019881657.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019874816.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049817874.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_019869649.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019866601.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019869935.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049817017.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049819377.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_049823956.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049820887.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019866608.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_049826381.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019869988.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049826113.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019871075.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019878000.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049823668.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_049820868.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049825130.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019881764.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_019864733.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049824165.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049821615.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049825247.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049824160.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049819758.1	6	Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-114508	"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis"
XP_019874746.2	4	Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6	"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate"
XP_019865288.2	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_049826593.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019870604.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019874956.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019866198.2	30	Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-8951664	"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"Orc1 removal from chromatin";"Neddylation"
XP_049816972.1	17	Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-174178;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-9022692;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2467813	"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"RHO GTPases Activate Formins";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human papillomavirus infection";"SUMOylation of DNA replication proteins";"Regulation of MECP2 expression and activity";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Separation of Sister Chromatids"
XP_019874794.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_019874584.2	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine"
XP_019875761.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_019868680.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049817233.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019871668.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_019871137.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049823498.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_019876003.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049825254.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049822916.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049821113.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_019876987.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049826402.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019867936.2	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_049821817.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_019865078.2	11	Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-9008059;Reactome: R-HSA-909733;Reactome: R-HSA-210990;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-912694	"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"PD-1 signaling";"Interleukin-37 signaling";"Interferon alpha/beta signaling";"PECAM1 interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Regulation of IFNA signaling"
XP_049818239.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049823471.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_049817246.1	5	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_019869178.1	10	MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042	"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)"
XP_019880696.2	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_049826490.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019868561.2	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_019875868.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019872322.2	9	MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7115;Reactome: R-HSA-1475029	"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide"
XP_019873716.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-69017;Reactome: R-HSA-69205	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription"
XP_049817284.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049820941.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019865525.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019870631.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820584.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019878196.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049822263.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_019871921.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049824101.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019874438.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049824958.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049826258.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049821818.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_019873070.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049818246.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_019873998.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019876578.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049817003.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049822949.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049826465.1	19	MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7210;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;Reactome: R-HSA-380270;MetaCyc: PWY-7187;MetaCyc: PWY-7205	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_019870543.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049819424.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049818282.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049819426.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019873765.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049820284.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049818216.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019864690.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049823370.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049825801.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
XP_049819521.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049826605.1	8	MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_049821251.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049826356.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049821688.1	3	KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757	"Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines"
XP_019866496.2	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_019870253.2	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_049824725.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_019868221.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_049820827.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_019869236.2	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism"
XP_019879086.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_019878739.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049823703.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019871070.2	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049817171.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_049822824.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_049824507.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049825089.1	19	Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-381426	"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron remodeling";"VLDL assembly";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_019872433.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019873023.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049825866.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019869995.1	22	MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7728;MetaCyc: PWY-6598	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis"
XP_019875478.2	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_019870962.2	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism"
XP_049819740.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049821907.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_049824204.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_019876358.2	29	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-5696400	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER"
XP_019875289.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121	"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI"
XP_049820889.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019869535.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049822266.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049823885.1	9	Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_049816944.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049822500.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019868085.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_019874674.2	4	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505	"Mitochondrial protein import";"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_019870796.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049823045.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049819258.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_019870076.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_049822694.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049818215.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019871762.2	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049824182.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049820937.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821012.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
XP_019871858.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049821234.1	5	MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_049822635.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019874474.2	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_019865205.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049818867.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865551.2	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_019871826.2	24	Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-163359	"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation"
XP_049820997.1	3	KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_019872645.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_019869811.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_019870030.2	4	Reactome: R-HSA-2408557;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_019875403.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049826615.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_019870693.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019873795.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019881611.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_019870557.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_049818252.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_019870767.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019871194.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049823529.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_049817071.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049817427.1	25	Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1"
XP_019872962.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049826675.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)"
XP_019867051.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049823261.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-3371497	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049826097.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019872113.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_049821735.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_019864877.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_019869022.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049818262.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049824906.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049826119.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_049824321.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049818179.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049824905.1	4	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_019876917.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019865204.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Neutrophil degranulation"
XP_019872438.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434	"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Aggrephagy";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019865556.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling"
XP_049821863.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_019879604.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019869112.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049823777.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049820618.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation"
XP_019866106.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_019876136.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_019866769.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_019874225.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049818092.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049821729.1	5	MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_019874959.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_019876400.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049824638.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_049818109.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019864743.2	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019869957.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_019877631.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_019871997.2	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049819554.1	19	MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-7383	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049824170.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049817244.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019880286.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_019877290.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049825985.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019867394.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_019865709.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_019872321.1	9	MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-241	"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_049818468.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049824123.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
YP_009437731.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049819173.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817720.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_019877155.1	6	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;MetaCyc: PWY-6580	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_049822546.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049817277.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_019868198.2	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_019865110.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019867382.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049823647.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019878456.1	52	Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-427413	"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression"
XP_049824848.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019869427.2	10	KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263	"Carbon fixation in photosynthetic organisms";"Glycolysis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis"
XP_019875002.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_049817816.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049818106.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049822050.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049818413.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049826363.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_019874690.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_049817829.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049820493.1	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Recycling pathway of L1";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_019869240.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019874025.2	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049826306.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_019880946.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019875892.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_019868916.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019872372.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019869927.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049820168.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019879621.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019871015.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049820671.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Downstream TCR signaling";"Degradation of DVL";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex"
XP_049819636.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019872859.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049818010.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049817297.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019874257.2	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_019867602.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049818258.1	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049817407.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019869634.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_019870442.2	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_019872069.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_019874742.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_019878369.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049817968.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_019875977.2	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-6309	"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_049818526.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049825828.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049821870.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_019865279.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049821602.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019874968.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820935.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049818116.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049823958.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817610.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049822722.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_049820862.1	4	Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC"
XP_049822124.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_019867419.2	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_049817245.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019877273.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049825576.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049820289.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019868935.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049822625.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049826719.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
YP_009437740.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019865268.2	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049826162.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049824006.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019880895.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019868312.1	6	MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation"
XP_019867658.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049820296.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_019864783.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6842	"Glutathione metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II"
XP_049821935.1	3	KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors"
XP_019881628.2	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049826302.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019871451.2	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049824164.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019877571.2	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_019874323.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049819123.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_019865561.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_019868761.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049819524.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049825244.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_019871393.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019873492.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs"
XP_049823820.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019871691.1	10	KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11	"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism"
XP_019871885.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049820129.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_019868679.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_019872621.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049820616.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_019868841.2	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_019873131.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019876668.2	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_049821403.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_019866360.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_019876932.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019879070.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_019875340.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_019867908.2	4	Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"ECM proteoglycans";"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_019875580.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569	"HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049821937.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049826683.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049825061.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049823754.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049822504.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019868025.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_019877698.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049824828.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_019870237.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049822003.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019880314.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_019871403.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049819924.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_019879534.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049824580.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_019877066.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_019869476.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049821988.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Kinesins"
XP_019878270.2	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049823521.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_019874457.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_019873761.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019869702.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034	"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Activation of SMO";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_019874153.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_019881434.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism"
XP_019876752.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy"
XP_049824187.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_049817687.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049820176.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_049818240.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019869306.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1	"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism"
XP_019869963.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_019874350.2	17	Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381	"Carnitine metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Pyruvate metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_019866473.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049817887.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049822903.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049819856.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_019872847.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049817262.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019868508.2	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_019872405.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019864605.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049819526.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049824360.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_019871621.1	10	Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-399719	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors"
XP_049817871.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019866612.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_019875197.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_019880249.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019865866.1	4	KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_019872770.2	7	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-373753	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Nephrin family interactions"
XP_049819573.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_019874462.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_019871375.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_019880762.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_019867832.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_019873594.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818451.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531	"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus"
XP_019870897.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_019865591.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049824814.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_019868230.2	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310	"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Fanconi Anemia Pathway"
XP_019877852.1	7	KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-7625;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11	"Glycerophospholipid metabolism";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_049826795.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049825949.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019877060.2	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049819518.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019873321.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_019872538.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_019876267.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019880239.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_019870781.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049817361.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_049823346.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019869651.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019875133.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049826118.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049820241.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_019868907.2	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_019870678.2	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049818514.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019880801.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049826213.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049823356.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049824490.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049826016.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019872384.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049819319.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_019874938.2	16	Reactome: R-HSA-1963642;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-1251985;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-6811558;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604	"PI3K events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Nuclear signaling by ERBB4";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling"
XP_019871670.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049823953.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049823892.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019867389.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049823297.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049821989.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"Kinesins";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019869149.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019880698.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049817898.1	7	Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614	"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrofolate biosynthesis"
XP_019870298.2	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_049820728.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_019872686.1	8	Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_019874137.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019878851.1	52	Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-749476;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-113418	"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Abortive And Retractive Initiation";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex"
XP_019869850.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_019864982.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090	"Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures"
XP_019877772.2	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049819504.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019875615.2	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_019880956.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_019865451.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019866516.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049824328.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865733.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_049823039.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049821660.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_019868806.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553	"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Neddylation";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs"
XP_049819072.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_019874505.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019868291.1	5	MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_019881813.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019875642.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_049820901.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_019869628.1	14	KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622	"Cyanoamino acid metabolism";"Photorespiration ";"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"Methane metabolism";"Folate transformations I";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)"
XP_019881687.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_049825868.1	13	Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway"
XP_019865924.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_019881255.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_019873699.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_019880985.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_019864698.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_019871014.2	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_019871951.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019874635.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049817324.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019879516.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049821838.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019878799.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049821314.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049826352.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049818409.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049820030.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878	"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport"
XP_049818458.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_019881519.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049818041.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_019868361.2	5	KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4	"Butanoate metabolism";"Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation"
XP_019864655.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_019874378.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764	"Methylation";"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_019868179.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813	"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"Recycling pathway of L1";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids"
XP_049819191.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019870547.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049821715.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_019881338.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049825533.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049825310.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation"
XP_019879856.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_049823691.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019867327.1	10	Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901	"Glycolysis";"Carbon fixation in photosynthetic organisms";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_019871365.1	11	Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-611105	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport"
XP_019881508.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049819395.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019868408.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_019875525.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049817743.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019867815.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_019865187.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019871796.2	8	Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019880664.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_019876748.2	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_019865549.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049821206.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_019869136.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_019880474.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_049824747.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049826433.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_049821041.1	26	Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-389977	"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway"
XP_019867753.2	27	Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749	"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs"
XP_019865430.1	13	KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-2201;MetaCyc: PWY-2161	"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Folate polyglutamylation"
XP_019872885.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019876427.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_049818336.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049824251.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_019872836.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019873424.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049820869.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049822709.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_019869322.1	30	Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;Reactome: R-HSA-9634638;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-198323;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-8948751;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-69656;Reactome: R-HSA-198693;Reactome: R-HSA-111447;Reactome: R-HSA-389513;Reactome: R-HSA-8941332;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-199418;Reactome: R-HSA-6804759	"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Regulation of localization of FOXO transcription factors";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Cyclin E associated events during G1/S transition";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"Regulation of PTEN stability and activity";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Acetylation";"Cyclin A:Cdk2-associated events at S phase entry";"AKT phosphorylates targets in the nucleus";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"RUNX2 regulates genes involved in cell migration";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Association with Co-factors"
XP_019870807.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_049824984.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_019868351.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049824499.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049822784.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049821258.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049818398.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_019864947.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019877652.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049821235.1	5	MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_049823015.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049820530.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019880645.1	7	Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis"
XP_049821659.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_019875066.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049824908.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PC";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis"
XP_019868977.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049818864.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049821313.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049819015.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_019881827.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049822353.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049821773.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_019870457.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049822519.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_019866157.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019870707.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_019872207.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_019876677.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049819428.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_019873748.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049824564.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_019877954.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_049824045.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049820262.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019876419.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049826545.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049820988.1	14	MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5076;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767	"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"L-valine degradation II";"L-isoleucine biosynthesis V";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"L-leucine degradation III";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)"
XP_049821709.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_019881655.1	6	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731;MetaCyc: PWY-7238	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Starch degradation III";"Sucrose biosynthesis II"
XP_019866562.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_019873111.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_049826809.1	31	MetaCyc: PWY-5971;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-5973;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-4381;MetaCyc: PWY-5994;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWY-6282;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-5366;Reactome: R-HSA-2426168	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"ChREBP activates metabolic gene expression";"";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)"
XP_019880404.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_019874813.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019878712.2	8	Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049823008.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-428540	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions";"Activation of RAC1"
XP_049817886.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019879886.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019874242.2	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_019878183.2	18	MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049821681.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_019880545.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-532668;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Degradation of DVL";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_019868059.1	5	Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7282	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_019867829.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_019874567.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049821839.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049819599.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_019871692.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_049825502.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019878959.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821454.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019874020.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826062.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019872004.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049821028.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049820330.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_019864695.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
YP_009437739.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019873320.2	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_019876092.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818721.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019881305.2	21	MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7224;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187	"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Thiamine metabolism";"CMP phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_019867624.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878	"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport"
XP_019881598.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049817516.1	7	Reactome: R-HSA-140837;Reactome: R-HSA-114608;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-418594;Reactome: R-HSA-8957275;Reactome: R-HSA-375276	"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (i) signalling events";"Post-translational protein phosphorylation";"Peptide ligand-binding receptors"
XP_049823643.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049824724.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_019875766.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049820031.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049819313.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_019870758.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764	"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling"
XP_019868366.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_019876328.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049825489.1	12	MetaCyc: PWY-7118;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1	"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049819637.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019880243.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049823148.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-5136	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049817450.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049817388.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049824441.1	18	MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Synthesis of PA";"alpha-Linolenic acid metabolism"
XP_019865320.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_019880326.2	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_019875198.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_019871032.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress"
XP_019868270.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019865255.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_019872848.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019865502.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_049820089.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_019879682.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_019870598.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019869113.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_019867328.2	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_019875217.2	5	KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;MetaCyc: PWY-7185;Reactome: R-HSA-6798695	"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Neutrophil degranulation"
XP_019873559.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019867904.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049817152.1	7	KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791	"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III"
XP_019877354.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174048	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049825466.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_019870809.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_019874295.1	7	KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism"
XP_019876118.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019873766.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049818619.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049819475.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019880864.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049821766.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_019868913.2	31	MetaCyc: PWY-5971;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-6519;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-6799;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-5147;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWY-6282	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)"
XP_049822299.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049817955.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_019868173.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049823144.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049823818.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049819788.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019870112.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049821008.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_049823489.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019876444.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_019871860.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_049823151.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049822929.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6952	"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerophosphodiester degradation"
XP_049823573.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019865480.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724	"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Regulation of PTEN gene transcription"
XP_019865913.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049825348.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333	"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049819682.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019874514.2	11	MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6607	"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Theophylline degradation";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I"
XP_049817847.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049820749.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019867857.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049823432.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049818942.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_019870269.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_019864702.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_019869931.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_019878497.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019881857.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_049822123.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_019870996.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_019868618.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_019873351.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis"
XP_019870134.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019867333.2	9	Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_049822639.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049818508.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019864908.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049824075.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_019866774.2	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_049820204.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_049826472.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_019876254.2	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy"
XP_049825578.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_019877818.2	6	MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III"
XP_019867912.2	31	MetaCyc: PWY-8049;MetaCyc: PWY-6282;MetaCyc: PWY-7388;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-4381;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-5971;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-5142	"Pederin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway"
XP_049821378.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019879220.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019868643.2	12	Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-1187;MetaCyc: PWY-801	"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion"
XP_049819789.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049823161.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019865278.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis"
XP_019872840.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019866729.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049821852.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_019872922.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_019879887.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019873977.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019870895.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049823584.1	7	MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6737;Reactome: R-HSA-6798695	"Starch degradation II";"Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Neutrophil degranulation"
XP_019871558.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_019866947.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_019872819.1	10	Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7187	"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_019864622.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_019865917.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019866848.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019871099.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019867650.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019881608.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049824438.1	18	KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_049817740.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019871766.1	14	MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis"
XP_049818391.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049823525.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_019873446.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049825411.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745	"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"LDL clearance";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_019869645.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049817680.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049818985.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+"
XP_019867842.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049823485.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_019866703.1	17	Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174411	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere"
XP_049821252.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019868330.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049824070.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs"
XP_049819568.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_049818450.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3301854	"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly"
XP_019872842.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019865642.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_019868669.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768	"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_019864920.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_019866957.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_019867364.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049823780.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_019869210.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019869260.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049824528.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049824497.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049818915.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_019868842.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019866501.2	6	Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398	"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway"
XP_049826219.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049820505.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_019872157.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_019873277.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019871358.2	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019870319.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049819063.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019872166.2	13	MetaCyc: PWY-5132;Reactome: R-HSA-71384;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-7857	"Lupulone and humulone biosynthesis";"Ethanol oxidation";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis"
XP_019868981.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_019869138.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049822637.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019880809.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_019877733.2	11	KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206	"Riboflavin metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_049821958.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019880954.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_019875063.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_019881289.2	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_019868527.2	5	Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049823496.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049824531.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049825802.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)"
XP_019873152.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049826396.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049818815.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019869208.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049821157.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019879760.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019873904.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_019867002.1	11	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_019865775.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_019866279.2	8	Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_019865197.2	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_019874711.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_019869016.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049826030.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019881375.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019877737.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049821488.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003	"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Purine metabolism";"Glycerol degradation to butanol"
XP_019877633.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_019879098.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817932.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_019875112.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019869594.2	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049819855.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049825935.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049821553.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019873432.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019869170.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049820874.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_019875458.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019881352.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_019868416.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049826042.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049819366.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019873763.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049817653.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_019872498.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_019881652.2	8	Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049817196.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049819244.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_019876368.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049818111.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019872334.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019874978.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_019867884.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_019869929.2	27	Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-168325	"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis"
XP_049826470.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049819589.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049817953.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_019874111.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_019874122.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817690.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019864913.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049824323.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049824510.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_019865138.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553	"O-linked glycosylation";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs"
XP_019874001.2	22	Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-7385;MetaCyc: PWY-5384;Reactome: R-HSA-6798695;MetaCyc: PWY-622;MetaCyc: PWY-5514;MetaCyc: PWY-5659;MetaCyc: PWY-7238;MetaCyc: PWY-6981;KEGG: 00520+5.3.1.9;KEGG: 00010+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-621;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-6992;MetaCyc: PWY-5054;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6142;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347	"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation IV (sucrose phosphorylase)";"Neutrophil degranulation";"Starch biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"GDP-mannose biosynthesis";"Sucrose biosynthesis II";"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Sucrose degradation II (sucrose synthase)";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"Gluconeogenesis";"1,5-anhydrofructose degradation";"D-sorbitol biosynthesis I";"Starch and sucrose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Sucrose biosynthesis III"
XP_049820171.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly"
XP_049825511.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_019871761.1	7	MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_049826193.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049817285.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049821737.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_019868283.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019866924.2	5	KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_019864789.1	5	Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756;Reactome: R-HSA-936440	"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling"
XP_049818764.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049821382.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-8939243	"Interleukin-7 signaling";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019873129.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019880910.1	16	MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5749;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.4	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Itaconate degradation";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism"
XP_019874473.2	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_019878603.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_019871179.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019864777.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019869271.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019873132.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049818115.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049818745.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692	"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity"
XP_049817345.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049821392.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049820154.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019866013.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6"
XP_019879433.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_019871148.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019874198.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049823629.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_019866980.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049817872.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019871777.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019869214.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049823167.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049823766.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049818254.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049817811.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_019873234.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019868467.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_019872116.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_019880347.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004	"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
XP_049820804.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049824379.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019870251.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_019867668.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_019881676.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_049817290.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049826779.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049826631.1	11	Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-2559582;Reactome: R-HSA-2871796;Reactome: R-HSA-8862803;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-8943724	"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated MAPK activation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN gene transcription"
XP_019873188.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_019864581.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049826211.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_019872485.1	5	MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_019881947.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049817499.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_019881326.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049817631.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049823694.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049825277.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049819763.1	6	Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1250196	"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"SHC1 events in ERBB2 signaling"
XP_019871068.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049821760.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049824568.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019874768.2	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_019875679.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism"
XP_019871033.1	26	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878	"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport"
XP_019869818.2	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_019869598.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_019865021.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_019867176.2	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_019868615.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_019870639.2	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049817070.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019869507.2	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049820597.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_019865699.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049824003.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019874420.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019876638.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817654.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019874923.2	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_049818768.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_019880549.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-6142	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_019866790.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019870133.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019875627.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019880328.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Neutrophil degranulation";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_049823241.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049818802.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3214841;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"PKMTs methylate histone lysines";"Collagen degradation";"Collagen chain trimerization"
XP_019881898.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019867885.2	24	Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;Reactome: R-HSA-5218921;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1	"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"Activation of AKT2";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"RSK activation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated cell proliferation";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Relaxin signaling pathway";"Integrin signaling";"PI3K-Akt signaling pathway"
XP_019873408.1	17	MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7224	"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Purine deoxyribonucleosides salvage"
XP_049817902.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019865575.2	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049820029.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation"
XP_049826469.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049825913.1	14	MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213	"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE"
XP_019876505.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019870065.2	9	MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism"
XP_019868616.2	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex"
XP_019871498.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019874857.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019881346.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049821149.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_019867161.2	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049817705.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049823803.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_019871629.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_019878328.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_019872715.2	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049821658.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_019872624.2	27	Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214	"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins"
XP_019872369.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049821203.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_019875259.2	60	MetaCyc: PWY-7654;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7779;Reactome: R-HSA-77288;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6583;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17;Reactome: R-HSA-77350;Reactome: R-HSA-77305;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6945;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-6883;MetaCyc: PWY-5109;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;Reactome: R-HSA-77348;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-6435;MetaCyc: PWY-7656;Reactome: R-HSA-77310;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7007;Reactome: R-HSA-77285;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7216;Reactome: R-HSA-77346	"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Propanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid degradation";"Tryptophan metabolism";"Caprolactam degradation";"Tryptophan metabolism";"2-methylpropene degradation";"Toluene degradation";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Benzoate degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Fatty acid elongation";"Geraniol degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol I";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Phenylalanine metabolism";"Fatty acid salvage";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Acyl chain remodeling of CL";"Geraniol degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol II (engineered)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Androstenedione degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Limonene and pinene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"4-hydroxybenzoate biosynthesis III (plants)";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"beta-Alanine metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Lysine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA"
XP_049821784.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049817606.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_049821861.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_049822145.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination"
XP_049821465.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019866265.1	8	KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis"
XP_019875612.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019875221.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019871907.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019867768.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049818571.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019866605.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019879176.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946	"RAF activation";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_049819204.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049826120.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019876066.2	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049822686.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049818266.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_049825745.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049823454.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation"
XP_019866104.2	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049818845.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049817868.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049822907.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_019881576.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049826345.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049818412.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_019881360.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_019866956.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_019871250.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_019871182.2	15	Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-2559582	"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)"
XP_019869991.1	5	MetaCyc: PWY-6289;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220	"Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism"
XP_019869734.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049820446.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-8937144	"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Endogenous sterols";"Xenobiotics";"Aryl hydrocarbon receptor signalling"
XP_019870451.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019872937.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_019870532.2	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_019876270.2	15	KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004;Reactome: R-HSA-70171	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Purine metabolism";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis"
XP_049819750.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049823487.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_019870162.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019867132.2	8	MetaCyc: PWY-6309;MetaCyc: PWY-7733;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00380+3.5.1.9	"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Tryptophan metabolism"
XP_019879272.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019867019.2	52	Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72086	"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping"
XP_019872359.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049822759.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049817391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817958.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_019872144.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_019867784.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049824440.1	18	Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PA";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_019867752.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019866486.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049826457.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA"
XP_019874278.2	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_019868833.2	13	Reactome: R-HSA-202433;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;MetaCyc: PWY-6351;Reactome: R-HSA-2871796;MetaCyc: PWY-6367	"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"DAP12 signaling";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated MAPK activation";"D-myo-inositol-5-phosphate metabolism"
XP_019868089.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049818380.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_019871139.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019880246.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019868565.2	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_019881710.1	7	KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_049823325.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_019881877.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049823781.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_019867398.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049824326.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019876706.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049824184.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049824159.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019878827.2	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049822626.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049821525.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_049821738.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_049817983.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_019866392.2	4	MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_049818181.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_019875007.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019881583.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049819923.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049826620.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019880069.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019872967.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019874793.2	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins"
XP_049820224.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_019871591.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049819551.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019871875.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_019869298.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019869011.2	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_019879261.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_019881033.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_049824163.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019867896.1	18	KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-6728	"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Gluconeogenesis";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle"
XP_019873385.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_049818253.1	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049822088.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination"
XP_049825841.1	26	Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158	"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_019871002.1	8	MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049818568.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_049819810.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049820871.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049826435.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_049819756.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_019877306.1	5	MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_019873801.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049824063.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019871901.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_049822150.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049819562.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_019872455.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019869339.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;MetaCyc: PWY-6854	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)"
XP_019881245.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019874899.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019880028.2	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049820602.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_019868522.1	7	MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis"
XP_019877476.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049825598.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019872019.1	42	KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6863;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7654;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7216;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-5136;MetaCyc: PWY-7656;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5109;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7726;MetaCyc: PWY-6944;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361	"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Phenylalanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Fatty acid elongation";"Toluene degradation";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to hexanol (engineered)";"Propanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Tryptophan metabolism";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Limonene and pinene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation II (plant peroxisome)";"Spodoptera littoralis pheromone biosynthesis";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Glutaryl-coa degradation";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Androstenedione degradation";"Fatty acid salvage";"Lysine degradation";"Benzoyl-coa degradation I (aerobic)"
XP_019869557.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_019880572.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_019866643.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_019880452.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_019870260.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis"
XP_019866841.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019865499.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_019874796.1	14	MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-4302;Reactome: R-HSA-611105	"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport"
XP_019872373.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019872531.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_049824816.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019864926.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019870040.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019877595.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049825730.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049817374.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019873416.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019876379.2	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049817482.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049824332.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019866607.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_049819350.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019874395.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_049817957.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049821024.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019874528.2	11	MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;Reactome: R-HSA-8851680;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6999;Reactome: R-HSA-74259	"Guanosine nucleotides degradation II";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Theophylline degradation";"Purine catabolism"
XP_049818507.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019867767.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019868480.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049822622.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019869303.1	10	KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1	"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis"
XP_049826761.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019873355.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061	"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_049826670.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_019867130.2	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049825362.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019877369.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049824533.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019866307.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049822803.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_019866499.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_019866949.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049822612.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049824812.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_019869347.2	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049822787.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049818615.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_019878853.1	52	Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72165	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway"
XP_019876206.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5607761	"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"Degradation of DVL";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_019872971.2	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049818612.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_019874718.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019866346.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049823826.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019867612.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049826676.1	8	MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_019870196.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_019866301.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019881960.2	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate"
XP_049822721.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_019866271.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_019880901.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049818416.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_019880128.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061	"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_049825622.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049817314.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019878218.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_019868854.1	6	KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-2942;MetaCyc: PWY-8088;MetaCyc: PWY-5097	"Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Dipicolinate biosynthesis";"L-lysine biosynthesis VI"
XP_049818871.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_019877253.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_019865717.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019867531.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019867622.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049825463.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019877739.2	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_019870168.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049819050.1	10	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5576893;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6802952;Reactome: R-HSA-380270;Reactome: R-HSA-5576890;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Phase 2 - plateau phase";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Signaling by BRAF and RAF fusions";"Recruitment of mitotic centrosome proteins and complexes";"Phase 3 - rapid repolarisation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019871543.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568	"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_019869670.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049824569.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049824267.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019881216.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_049825678.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049826024.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019865343.2	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049819944.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_019869459.2	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049825577.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049824200.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865076.1	19	Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482	"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"EGFR downregulation";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation"
XP_019880736.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_019878587.2	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_019869646.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019873703.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049824110.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049820919.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_019881247.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049820506.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049821200.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049826294.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_019873527.2	13	Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662	"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"EPHB-mediated forward signaling"
XP_049820162.1	12	MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_019871856.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049825766.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019880587.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019880499.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_019873919.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_019872666.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049821288.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_019874887.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049825323.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-1855204	"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol"
XP_019866284.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049817409.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049822804.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049817746.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-912631	"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL"
XP_019864766.2	13	KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-6842	"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II"
XP_019877377.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049826270.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_019868592.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_049823801.1	3	Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049825260.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_049822604.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism"
XP_019866266.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814	"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes"
XP_019881522.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_019871298.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049826280.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049819522.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019869160.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019880734.2	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019869602.2	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_019868109.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_019880199.2	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_019880697.2	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_019881466.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019869256.2	5	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_049823469.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049825516.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049818813.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019879646.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049822642.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_019866293.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_019865233.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019866797.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019865708.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_019865630.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049821911.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_019875209.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_019881584.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019875626.2	14	MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_019878002.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_019864914.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7226	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_019874121.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817853.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_019871646.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_019877003.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_019880958.1	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_049825269.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049824899.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049822708.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019881034.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049826135.1	3	Reactome: R-HSA-1296072;Reactome: R-HSA-5576890;Reactome: R-HSA-5576893	"Voltage gated Potassium channels";"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase"
XP_019869956.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049818891.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049817981.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049821400.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049822286.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019872450.2	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_049817385.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049824570.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_019878801.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019875932.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_019870935.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_019873630.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019866186.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_019874577.2	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_019872230.2	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049818584.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_019869650.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019866300.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_019868421.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049819076.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049826657.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
XP_049826756.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049823273.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049817665.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_019877879.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049825842.1	26	Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-1234158;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862	"Attenuation phase";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"RORA activates gene expression";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_019874860.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_049817800.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_019874010.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049825904.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049824415.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746	"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein"
XP_019879076.2	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049824087.1	25	Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-381771;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-416476	"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events"
XP_019881480.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Neutrophil degranulation"
XP_049822756.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019867986.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019865263.1	4	MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine"
XP_019872418.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019880462.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049817278.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019871106.2	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_019868322.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049823582.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-7238;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;Reactome: R-HSA-6798695	"Starch and sucrose metabolism";"Starch degradation II";"Sucrose biosynthesis II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Neutrophil degranulation"
XP_019872098.2	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383	"Neutrophil degranulation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049817142.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_019873843.1	11	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049818400.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_019875335.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_049821479.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019876643.2	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction"
XP_019867669.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049819190.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019881648.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019869647.2	19	MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7187;Reactome: R-HSA-380270;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_019869342.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_049819043.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_019874919.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_019868885.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049817356.1	13	KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-7909	"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate polyglutamylation";"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)"
XP_049817035.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049823802.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_049824004.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019869643.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_019881237.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049823683.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_049818444.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049818243.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_049823778.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_019875216.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_019876425.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_019879761.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049824280.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_049817132.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049821497.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049826555.1	4	Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019877477.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019876913.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049821289.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_019874230.2	5	MetaCyc: PWY-8060;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-6798695	"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation"
XP_019873433.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049817970.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049817686.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049826533.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346	"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis"
XP_049817707.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049825689.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049826101.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019865566.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019873634.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_019874144.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019870975.1	18	MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_019866736.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019871719.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_019873536.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865276.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_019881196.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_019874958.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049826359.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_019872452.2	10	Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_049824240.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_049819035.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_019876946.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049824122.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-176034	"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins"
XP_049819945.1	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism"
XP_049818113.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019875370.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049823759.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_019868983.2	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049820612.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_049826662.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019867717.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_019868431.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019877403.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_019871846.2	9	Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-114608	"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation"
XP_019874767.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_019874524.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_019866818.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049825943.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049818616.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway"
XP_049819349.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019879594.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_019865750.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019864974.1	21	MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7221	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis"
XP_019869091.2	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_019866433.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019868329.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049824439.1	18	KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788	"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC"
XP_019873525.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019867438.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049819507.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049824013.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868962.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_049825382.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019881186.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange"
XP_049817885.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019875841.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826351.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049817648.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_019870896.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_019872333.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049826303.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019873464.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_019865956.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019874493.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049818873.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_019872077.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019870035.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049824381.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019872371.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_019875158.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_019872790.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_019866046.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049823330.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_019880925.1	10	Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916	"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation"
XP_049818188.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019878219.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019876016.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-77387	"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Insulin receptor recycling"
XP_019871959.2	56	Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323	"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling"
XP_049818910.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_019868259.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049817344.1	7	MetaCyc: PWY-7185;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism"
XP_049821928.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049821634.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5545619	"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_049822316.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049818506.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049822196.1	17	MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-1622	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)"
XP_049819367.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019874795.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_019868775.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685	"Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species"
XP_019864984.2	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR"
XP_049821910.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_019878496.2	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142;Reactome: R-HSA-4549349	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_049820828.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_019875075.2	6	MetaCyc: PWY-6952;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;Reactome: R-HSA-163560	"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism"
XP_019866709.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049820786.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_019866954.1	29	Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-5696400	"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Dual Incision in GG-NER"
XP_049824065.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019872580.2	14	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_049825363.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049822197.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation"
XP_019865498.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_019877260.2	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049823758.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049822760.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019881398.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_019868753.2	57	Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585	"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G"
XP_019876378.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049821308.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_019874459.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_019865541.2	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_049826397.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049818683.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019871805.1	4	KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_019865648.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049824770.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism"
XP_049824827.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049826269.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_019878679.2	6	KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017	"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
YP_009437736.1	7	MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;Reactome: R-HSA-611105	"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Fe(II) oxidation";"Respiratory electron transport"
XP_049821398.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049825912.1	1	Reactome: R-HSA-419771	"Opsins"
XP_019864567.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_019867615.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_019870082.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_019876506.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019870270.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_019873921.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049820524.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_019865229.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019868915.2	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_049826029.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049826361.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_019868722.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049821713.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_019878003.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019869455.2	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_019881215.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7	"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis"
XP_019872921.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049818525.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049823389.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_019866631.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_019872966.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049824508.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019875543.2	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_019868735.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049822474.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_019871042.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019868145.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019870338.2	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_049825359.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_019876973.2	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_019869804.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation"
XP_049820603.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019869955.2	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049825236.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand"
XP_019868335.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049818751.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_019870154.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019872753.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049819502.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-983231	"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production"
XP_049821860.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_019877720.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019872682.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019866478.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_019866053.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019866979.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_019866033.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_019869083.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_049822228.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049824614.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_019874028.2	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049824567.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_019864823.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-525793	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Myogenesis"
XP_019871908.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019872415.1	8	Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6783310;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Fanconi Anemia Pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049821196.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019867016.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049826684.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019865690.1	10	MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11	"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_049824055.1	11	MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6607;Reactome: R-HSA-74259;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-5497	"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Purine catabolism";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation II";"Purine metabolism";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)"
XP_019880840.1	6	Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling"
XP_049819922.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_019869012.2	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049824199.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1"
XP_049823168.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049825534.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_019872375.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019881221.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis"
XP_049821938.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_019869514.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049821395.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049818411.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_019869556.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019871187.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019878209.2	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019881923.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049823756.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049821656.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049824530.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019874995.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019870709.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_019871238.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049821730.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_019879212.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049825615.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049824901.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019873378.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870	"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins"
XP_019869139.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_049817461.1	4	KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol"
XP_019878541.2	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_019867061.2	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_019876577.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_049823954.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019865289.2	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_019874226.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049823066.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_019875657.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049826434.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049825671.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019879458.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_019869302.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_019881844.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019880397.1	10	Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111463	"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs"
XP_019869640.1	17	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;KEGG: 05165+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-4615885;Reactome: R-HSA-9022692;Reactome: R-HSA-2500257;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human papillomavirus infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SUMOylation of DNA replication proteins";"Regulation of MECP2 expression and activity";"Resolution of Sister Chromatid Cohesion";"Thermogenesis";"Relaxin signaling pathway";"Separation of Sister Chromatids";"Mitotic Prometaphase";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"RHO GTPases Activate Formins";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_019868634.2	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_019869958.1	5	Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
XP_049819844.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049817575.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049826360.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049824169.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019865415.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019871029.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049825366.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049820223.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587	"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_019866280.2	4	Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814	"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes"
XP_049818038.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_019881198.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_019877375.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049823882.1	30	Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783	"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Neddylation";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome"
XP_019872082.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049820310.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947	"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049818464.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019881099.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6782315	"SRP-dependent cotranslational protein targeting to membrane";"tRNA modification in the nucleus and cytosol"
XP_049825734.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_019880970.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019868755.1	4	KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_049824479.1	31	MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-5366;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-5973;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-5994;MetaCyc: PWY-4381;MetaCyc: PWY-7746;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-5142;Reactome: R-HSA-9029558	"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"";"ChREBP activates metabolic gene expression";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_019875550.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_019875598.2	10	Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-1660499;MetaCyc: PWY-6352	"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis"
XP_049825554.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049825476.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_019872626.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019871289.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_019872126.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_019874478.2	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_019875566.1	10	MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_019872365.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049822651.1	5	KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism"
XP_049818494.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049820707.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism"
XP_019866156.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049820876.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049818805.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3214841;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"PKMTs methylate histone lysines";"Collagen degradation";"Collagen chain trimerization"
XP_049825543.1	9	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_019880863.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_019871337.2	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049823635.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049826403.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019871878.1	12	KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5340;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25	"Selenocompound metabolism";"Sulfur metabolism";"Purine metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Purine metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Sulfur metabolism"
XP_019864668.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_019873334.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049821285.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_019871091.2	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_019879213.2	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_019873611.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049824078.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids"
XP_019869307.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019869909.1	4	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69205	"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription"
XP_049826192.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019875542.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184	"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of DVL";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_049825351.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049823368.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049824852.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_019881109.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019872851.2	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_019880311.1	25	Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-381771;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-8964315	"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G beta:gamma signalling through CDC42";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK"
XP_019879078.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049824474.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049819790.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049826100.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821148.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049819776.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049818716.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_049825889.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019881851.1	7	Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-5696394	"UCH proteinases";"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER"
XP_019865147.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049819700.1	10	MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Other glycan degradation";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"HS-GAG degradation";"Sphingolipid metabolism"
XP_019869349.1	8	MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-7573	"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis"
XP_019865704.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_019879752.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_019875750.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_019871604.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019873301.2	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_019876143.2	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_049820782.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019873067.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866564.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_019865349.2	18	Reactome: R-HSA-8878166;Reactome: R-HSA-9617828;Reactome: R-HSA-5674400;Reactome: R-HSA-9616222;Reactome: R-HSA-187577;Reactome: R-HSA-8941855;Reactome: R-HSA-8866911;Reactome: R-HSA-69656;Reactome: R-HSA-2559582;Reactome: R-HSA-6785807;Reactome: R-HSA-69563;Reactome: R-HSA-198323;Reactome: R-HSA-69202;Reactome: R-HSA-6804116;Reactome: R-HSA-8852276;Reactome: R-HSA-69231;Reactome: R-HSA-69895;Reactome: R-HSA-2559586	"Transcriptional regulation by RUNX2";"FOXO-mediated transcription of cell cycle genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Transcriptional regulation of granulopoiesis";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX3 regulates CDKN1A transcription";"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"Cyclin A:Cdk2-associated events at S phase entry";"Senescence-Associated Secretory Phenotype (SASP)";"Interleukin-4 and Interleukin-13 signaling";"p53-Dependent G1 DNA Damage Response";"AKT phosphorylates targets in the cytosol";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cyclin D associated events in G1";"Transcriptional activation of cell cycle inhibitor p21";"DNA Damage/Telomere Stress Induced Senescence"
XP_019868038.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019876945.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049818218.1	10	Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916	"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation"
XP_019875644.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665	"Clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells"
XP_019873279.2	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_019869898.2	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)"
XP_019881044.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019871738.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049818524.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_019876481.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019873435.2	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination"
XP_049821710.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_019865840.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_019875481.2	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_019875833.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049824464.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019872340.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838	"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog 'off' state";"Activation of SMO"
XP_049824259.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049821763.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_019871532.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019881950.1	15	MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723	"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"Purine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt"
XP_049819033.1	10	Reactome: R-HSA-380284;Reactome: R-HSA-5576890;Reactome: R-HSA-380270;Reactome: R-HSA-6802952;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5576893;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Phase 3 - rapid repolarisation";"Recruitment of mitotic centrosome proteins and complexes";"Signaling by BRAF and RAF fusions";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Phase 2 - plateau phase";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_049817090.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_019877391.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049825691.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_019873875.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049817694.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049822920.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049817999.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019872148.1	30	Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-2564830;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73762	"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cytosolic iron-sulfur cluster assembly";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation"
XP_019880080.1	11	Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-6859;MetaCyc: PWY-7560;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7102;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922;MetaCyc: PWY-6383;MetaCyc: PWY-5123	"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"All-trans-farnesol biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_019877624.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049821611.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019874966.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019874429.2	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_019867219.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049822271.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049819062.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019870597.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019873115.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_019869655.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019865830.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019874034.1	8	Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
XP_049825954.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_019871684.2	5	Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049817736.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049817817.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_019880296.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019881212.2	13	KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_019881379.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_019874360.2	25	Reactome: R-HSA-8941858;Reactome: R-HSA-8934593;Reactome: R-HSA-8940973;Reactome: R-HSA-9018519;Reactome: R-HSA-8949275;Reactome: R-HSA-8939902;Reactome: R-HSA-8935964;Reactome: R-HSA-8931987;Reactome: R-HSA-8941332;Reactome: R-HSA-8878166;Reactome: R-HSA-8939242;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330;Reactome: R-HSA-8939236;Reactome: R-HSA-8939243;Reactome: R-HSA-8936459;Reactome: R-HSA-8951936;Reactome: R-HSA-8941326;Reactome: R-HSA-8941333;Reactome: R-HSA-8939247;Reactome: R-HSA-8939256;Reactome: R-HSA-8951911;Reactome: R-HSA-8941284;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222	"Regulation of RUNX3 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates osteoblast differentiation";"Estrogen-dependent gene expression";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX2 expression and activity";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in cell migration";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates p14-ARF";"RUNX2 regulates bone development";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis"
XP_049824334.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019870467.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_019871918.2	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_019866282.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_019875765.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049819821.1	4	KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4	"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism"
XP_019874931.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757	"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation"
XP_019870861.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA"
XP_019864904.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019871036.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049822660.1	21	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7219;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7221	"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis"
XP_049825111.1	4	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-6783310	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Fanconi Anemia Pathway"
XP_049821161.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019877940.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_019865095.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_019873229.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_019878322.2	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_019869890.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049822912.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019868225.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049820781.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049825437.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_019869778.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis"
XP_019868756.1	4	MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50	"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_049816973.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_049825567.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049824416.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-3108214	"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins"
XP_019868501.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049822447.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049819683.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049817859.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019874881.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019875998.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_019870060.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019877092.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049824292.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_019875531.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_019867440.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820451.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049820968.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_019869579.2	4	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism"
XP_019867473.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_019874460.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_019865397.2	7	Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)"
XP_019880264.1	8	Reactome: R-HSA-6796648;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-450341;Reactome: R-HSA-3214847;Reactome: R-HSA-9633012;Reactome: R-HSA-8943724;Reactome: R-HSA-2151201	"TP53 Regulates Transcription of DNA Repair Genes";"Circadian Clock";"Estrogen-dependent gene expression";"Activation of the AP-1 family of transcription factors";"HATs acetylate histones";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of PTEN gene transcription";"Transcriptional activation of mitochondrial biogenesis"
XP_049826133.1	3	Reactome: R-HSA-1296072;Reactome: R-HSA-5576890;Reactome: R-HSA-5576893	"Voltage gated Potassium channels";"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase"
XP_049820956.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_019871823.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_019865879.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019870902.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane"
XP_019875752.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049825389.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049824320.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_019880904.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_019865040.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_019868550.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475	"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_019872396.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_019866020.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_019868007.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_019875122.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049823337.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049825850.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019870323.2	8	MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-74217	"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism";"Purine salvage"
XP_049822129.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128	"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling"
XP_019870140.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019867889.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_019870754.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17	"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism"
XP_049825199.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019876271.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049821226.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_019865828.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049817024.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019881336.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019872088.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049821711.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049817786.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_019866855.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019878395.2	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_019881174.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049825731.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_019868006.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_019870518.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_019874268.1	9	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049822623.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019868993.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_019871560.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019875325.2	4	Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors"
XP_049821680.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019869725.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation"
XP_019872872.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019871199.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_019866482.2	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049822977.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_019874785.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_019869652.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049819267.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049818414.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049826467.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049823305.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_019878767.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019866786.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-381042	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression"
XP_019880027.2	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_049825610.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049817449.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;Reactome: R-HSA-70171	"Purine metabolism";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis"
XP_019876641.2	7	Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_019872352.1	17	Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-5685942	"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)"
XP_019868463.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_019881425.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_019873051.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019866057.2	7	Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-418594;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-375276	"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Peptide ligand-binding receptors"
XP_049826319.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_019866292.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695	"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events"
XP_019869953.2	5	Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661	"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation"
XP_019869080.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019873579.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_019878715.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51	"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism"
XP_019869286.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049819533.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019876165.2	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_019870572.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049822001.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019877996.2	20	Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312	"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1"
XP_049820735.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049818447.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001	"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade"
XP_019865045.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049819571.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019865084.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019867257.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049822902.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019873370.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_019877691.2	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_019870389.2	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_019865043.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019877272.2	4	Reactome: R-HSA-8866427;Reactome: R-HSA-983168;Reactome: R-HSA-9031525;MetaCyc: PWY-7511	"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination"
XP_019881347.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_049820085.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049819510.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019876943.2	5	MetaCyc: PWY-5981;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41	"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_019879680.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_019873069.2	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049820610.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_019881002.2	7	MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;Reactome: R-HSA-1483166	"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Synthesis of PA"
XP_049818827.1	12	Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1	"NRAGE signals death through JNK";"Rho GTPase cycle";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"PI3K-Akt signaling pathway"
XP_019865985.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
XP_019870994.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019876383.2	22	MetaCyc: PWY-6981;MetaCyc: PWY-7238;MetaCyc: PWY-7385;MetaCyc: PWY-5384;MetaCyc: PWY-622;Reactome: R-HSA-6798695;MetaCyc: PWY-5514;MetaCyc: PWY-5659;MetaCyc: PWY-8013;Reactome: R-HSA-5628897;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6142;MetaCyc: PWY-7347;MetaCyc: PWY-5054;KEGG: 00500+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-6992;Reactome: R-HSA-70171;MetaCyc: PWY-3801;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;KEGG: 00010+5.3.1.9	"Chitin biosynthesis";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis";"Neutrophil degranulation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"TP53 Regulates Metabolic Genes";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose biosynthesis III";"D-sorbitol biosynthesis I";"Starch and sucrose metabolism";"Gluconeogenesis";"1,5-anhydrofructose degradation";"Glycolysis";"Sucrose degradation II (sucrose synthase)";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
XP_049818747.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_049818675.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_019873792.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_019865853.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049819496.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019876951.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_019871873.2	56	Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276	"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Separation of Sister Chromatids";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_019875027.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_019881700.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049817327.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049817363.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019873796.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_019871334.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism"
XP_019881582.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
YP_009437737.1	7	KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-5083;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-4302	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation";"Complex I biogenesis";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)"
XP_019868487.2	33	Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-1169408	"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism"
XP_019871242.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019874414.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019871889.1	9	MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-7852	"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)"
XP_049825861.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019876452.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_019875990.1	58	Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-5689901;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69481	"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"Metalloprotease DUBs";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"G2/M Checkpoints"
XP_019866881.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049818020.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049820483.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049822961.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_019871790.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_019865550.2	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_019874993.2	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_019875130.2	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019867455.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_019870588.1	11	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human papillomavirus infection"
XP_019875855.2	57	Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858	"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity"
XP_049825594.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049821038.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I"
XP_019874626.1	18	Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Linoleic acid metabolism"
XP_049820263.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019864968.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019871072.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049821310.1	4	Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87	"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis"
XP_049820090.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_019870282.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019870038.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049819131.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_019881963.2	6	MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_049825558.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_019873460.2	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_049816970.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
XP_019871174.2	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_019876362.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_019874048.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_019874470.1	3	KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_049817901.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_019876167.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_019879515.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_049825529.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049824158.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049822860.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_049826504.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_019879836.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_049822308.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019876725.2	7	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049821774.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049825390.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_019873252.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049817465.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_019881517.1	29	Reactome: R-HSA-6803207;Reactome: R-HSA-3371453;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69541;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-6803204;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-349425;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5685938	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of HSF1-mediated heat shock response";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Stabilization of p53";"PI3K-Akt signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Methylation";"HDR through Single Strand Annealing (SSA)"
XP_019880346.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_019873588.2	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_049823123.1	44	Reactome: R-HSA-202670;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-5654732;Reactome: R-HSA-444257;Reactome: R-HSA-881907;Reactome: R-HSA-198753;Reactome: R-HSA-1295596;Reactome: R-HSA-879415;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5663213;Reactome: R-HSA-170968;Reactome: R-HSA-5674499;Reactome: R-HSA-5674135;Reactome: R-HSA-5654727;Reactome: R-HSA-6802948;Reactome: R-HSA-5668599;Reactome: R-HSA-2559582;Reactome: R-HSA-112409;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-9634638;Reactome: R-HSA-8939211;Reactome: R-HSA-9635465;Reactome: R-HSA-9627069;Reactome: R-HSA-6811558;Reactome: R-HSA-450341;Reactome: R-HSA-2029482;Reactome: R-HSA-5654733;Reactome: R-HSA-2871796;Reactome: R-HSA-456926;Reactome: R-HSA-162658;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654726;Reactome: R-HSA-982772;Reactome: R-HSA-2559585;Reactome: R-HSA-74749;Reactome: R-HSA-445144;Reactome: R-HSA-8940973;Reactome: R-HSA-375165;Reactome: R-HSA-3371453	"ERKs are inactivated";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Negative regulation of FGFR3 signaling";"RSK activation";"Gastrin-CREB signalling pathway via PKC and MAPK";"ERK/MAPK targets";"Spry regulation of FGF signaling";"Advanced glycosylation endproduct receptor signaling";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"RHO GTPases Activate WASPs and WAVEs";"Frs2-mediated activation";"Negative feedback regulation of MAPK pathway";"MAP2K and MAPK activation";"Negative regulation of FGFR2 signaling";"Signaling by high-kinase activity BRAF mutants";"RHO GTPases Activate NADPH Oxidases";"Senescence-Associated Secretory Phenotype (SASP)";"RAF-independent MAPK1/3 activation";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ESR-mediated signaling";"Suppression of apoptosis";"Regulation of the apoptosome activity";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Activation of the AP-1 family of transcription factors";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of FGFR4 signaling";"FCERI mediated MAPK activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Golgi Cisternae Pericentriolar Stack Reorganization";"mTOR signaling pathway";"Negative regulation of FGFR1 signaling";"Growth hormone receptor signaling";"Oncogene Induced Senescence";"Signal attenuation";"Signal transduction by L1";"RUNX2 regulates osteoblast differentiation";"NCAM signaling for neurite out-growth";"Regulation of HSF1-mediated heat shock response"
XP_049821051.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_019881920.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049821025.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049819479.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049820170.1	9	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_019874726.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_019879735.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049818669.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_019879131.2	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_019874549.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019878633.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_049817596.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019881361.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019877567.2	3	Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049819872.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_019872389.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019874652.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019880244.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_019876346.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019870465.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_049823527.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_019880869.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167200	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_019865265.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049824896.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019865079.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049822600.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_019873139.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_019867625.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Aggrephagy";"Separation of Sister Chromatids"
XP_049818112.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019867830.2	6	MetaCyc: PWY-7817;Reactome: R-HSA-1483166;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-5269	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PG";"Cardiolipin biosynthesis II"
XP_019877291.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019881588.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_019874977.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019879353.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049825865.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049824919.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049819202.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049822000.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)"
XP_019873113.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049823642.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_019880543.1	18	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049823998.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_049823143.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019865012.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049821897.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation"
XP_049821259.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049822233.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817807.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_019866741.2	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_049817413.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049818051.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049819330.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_019871004.2	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_019870592.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049825860.1	13	KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Human papillomavirus infection"
XP_019864971.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019868355.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978	"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_049819792.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049821786.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_019871954.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049825851.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019876831.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_019872284.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_019879753.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019878659.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019864825.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049817252.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_019864817.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019866113.2	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049824500.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049820893.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8939243	"WNT mediated activation of DVL";"Synthesis of PC";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049821529.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049819795.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019868874.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_019867169.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049820647.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_019876942.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_019875788.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019874609.1	4	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_049824242.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019874941.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049817867.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019868710.1	17	Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 05163+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-4615885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9022692;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;KEGG: 04151+2.7.11.1;Reactome: R-HSA-68877;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2467813	"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate Formins";"Human cytomegalovirus infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SUMOylation of DNA replication proteins";"Human papillomavirus infection";"Regulation of MECP2 expression and activity";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"PI3K-Akt signaling pathway";"Mitotic Prometaphase";"Relaxin signaling pathway";"Thermogenesis";"Separation of Sister Chromatids"
XP_019871017.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049824825.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_019881845.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049824727.1	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019881589.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_019869406.1	12	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049819487.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019868603.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049822239.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_019866472.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_019873764.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019867226.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977	"Photosynthesis";"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling"
XP_019865365.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_019877628.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049818466.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019877452.2	6	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_019877073.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049825243.1	17	KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-5743	"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Pyruvate metabolism";"Biotin transport and metabolism";"Carnitine metabolism";"3-hydroxypropanoate cycle"
XP_019866245.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049819742.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_019873855.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_019867254.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-389977	"Mitotic Prometaphase";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway"
XP_019866886.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019870198.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049820225.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997	"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion"
XP_019864781.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_019864923.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019880386.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049825275.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019865545.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049822892.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_019867165.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049824083.1	4	MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_019871203.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019866343.1	9	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol"
XP_049824532.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019867366.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019877660.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_019881356.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870	"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins"
XP_049817696.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049826378.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019864761.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049817382.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_019881468.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019865221.1	10	Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-1169091	"Neddylation";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells"
XP_019877867.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049821957.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019871317.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019877448.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_019864962.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_019878529.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019879953.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049825207.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019881665.1	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019865955.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019879714.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049822607.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_049824551.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_019869989.2	56	Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Degradation of DVL";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_049826385.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049819576.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_019870468.2	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049818901.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019876398.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"mTOR signalling";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription"
XP_019874164.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019869981.2	30	Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783	"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Neddylation";"Orc1 removal from chromatin";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Circadian Clock";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome"
XP_019876179.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049821338.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749	"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated"
XP_019876121.2	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_049818461.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_049820560.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049817602.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_019873902.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_019876263.2	4	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_049823955.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019868743.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
XP_049822753.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_019875734.2	4	KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_019865974.2	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_019869490.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049821369.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019868015.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019864757.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049818383.1	19	MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7187;Reactome: R-HSA-380270;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049817170.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_019871054.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_019870909.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049826350.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049826281.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866068.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837	"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Separation of Sister Chromatids";"Degradation of DVL";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation"
XP_019880458.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_019866809.2	15	Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_019867922.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019866196.2	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_019875919.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049826535.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019869324.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019871763.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_019874996.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865882.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019871675.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-9603505;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167158	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"NTRK3 as a dependence receptor";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex"
XP_049822394.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049825324.1	9	Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476	"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events"
XP_019876399.1	16	Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-164939;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-182218	"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Gap junction degradation";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"LDL clearance";"MHC class II antigen presentation";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation"
XP_049817004.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049824613.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
XP_019870838.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_019871125.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019866616.1	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_019881729.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_049822823.1	9	Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex"
XP_019867218.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019866907.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049818259.1	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism"
XP_019866656.1	4	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism"
XP_049826048.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_019874211.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_019872868.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049819846.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049825614.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019866816.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049822322.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_019875593.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049825843.1	26	Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-933541;Reactome: R-HSA-5617472	"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049817669.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049819639.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049823776.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_019870714.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019872588.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_019868441.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism"
XP_019870252.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis"
XP_019874937.2	16	Reactome: R-HSA-1250342;Reactome: R-HSA-1250196;Reactome: R-HSA-1251985;Reactome: R-HSA-9664565;Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795	"PI3K events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling"
XP_049825844.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-381340	"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Attenuation phase";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation"
XP_049817164.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692	"HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity"
XP_049824161.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019864585.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019867796.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049825507.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486	"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis"
XP_049817956.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_019868742.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_019874774.2	7	Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049822347.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049824895.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019871848.2	9	Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6802952	"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling by BRAF and RAF fusions"
XP_019881433.1	12	MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions"
XP_049823827.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019866847.1	6	Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253	"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock"
XP_019870006.2	30	Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2644607;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-917937	"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport"
XP_049819771.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019881724.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019868543.2	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049821670.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_019874062.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049817386.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019875028.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_049821829.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019871190.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049819248.1	13	KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5132;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7857;MetaCyc: PWY-6672;MetaCyc: PWY-7118	"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Ethanol oxidation";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol"
XP_049824322.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049822198.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_019871669.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_019867629.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_019873802.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049817387.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019873261.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049817248.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_019869157.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019868462.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_019881809.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_019872608.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_019877513.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019872326.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049817683.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049817188.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_019871400.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_049818107.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-9648025	"snRNP Assembly";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation"
XP_019879383.2	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_019877406.1	28	Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-3371511;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5696400	"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HSF1 activation";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Meiotic recombination";"Dual Incision in GG-NER"
XP_019872482.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_019875181.1	14	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-68877	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase"
XP_019874530.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019872861.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex"
XP_019871639.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049820931.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049821719.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019874807.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
XP_019865536.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019874267.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_019864959.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768	"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_019870367.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049821355.1	30	Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-1169091	"Prolactin receptor signaling";"Neddylation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells"
XP_019866185.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_019870249.2	4	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_049817486.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019867609.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_019879072.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_049824976.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019865604.1	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_049821764.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049823497.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_019866613.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049820254.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_019871043.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049824054.1	11	Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606	"Purine catabolism";"Theophylline degradation";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Guanosine nucleotides degradation II"
XP_019871603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019867486.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events"
XP_049823433.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049825483.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_019868546.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_019878021.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049823206.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049818474.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049820891.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_049821163.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019871817.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_019866702.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606	"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_019871526.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049824358.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_019877939.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019864775.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_049820958.1	5	Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_019866147.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049821102.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049822485.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_049820777.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049818692.1	13	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7410;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-5123	"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_019879101.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019864876.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_019874029.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_019866959.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_019869224.1	5	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-5689603	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"UCH proteinases"
XP_019866281.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_049817564.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061	"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_049816969.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
XP_019870179.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049826722.1	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_019877282.2	4	MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_019866611.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019877644.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_019864541.2	6	Reactome: R-HSA-196819;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-6898	"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III"
XP_019868787.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019870801.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049821388.1	12	MetaCyc: PWY-801;MetaCyc: PWY-1187;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-2821;Reactome: R-HSA-71240	"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism"
XP_019874179.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049820872.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_019869491.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019864697.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_049819483.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_019881328.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049824957.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049822319.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049825460.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019874826.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_019866327.2	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049818676.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019870849.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323	"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling"
XP_019872283.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13	"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Fructose and mannose metabolism"
XP_019871143.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019872931.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_019865620.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_049819734.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049821559.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_019864711.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_019869186.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826220.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_049821099.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019867647.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_019870677.2	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_019864975.1	21	MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7205;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7224;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Thiamine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_049823761.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_019865126.2	33	Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-112382	"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin D associated events in G1";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_019870120.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_019870416.1	34	Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464	"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins"
XP_019875718.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049823460.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_049821610.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_019870362.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019864586.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_019875664.2	17	Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-176408	"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Regulation of APC/C activators between G1/S and early anaphase"
XP_019868274.2	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803211	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_049819876.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049823646.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049821909.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_019875838.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019880432.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_019874679.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019866761.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042	"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_019870903.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049824188.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors"
XP_019867696.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049824333.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019868356.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019872968.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049821619.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108	"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis"
XP_019872254.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_019879229.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049821249.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434	"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"RHO GTPases Activate Formins";"Recycling pathway of L1";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049825552.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019872792.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_019873656.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049822917.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049821736.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049818748.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11	"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Methane metabolism"
XP_019878852.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049823632.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049819588.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019872796.2	5	Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049824962.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019871387.2	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_019868936.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049821864.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_049819090.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049822697.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389977	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway"
XP_019865826.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019870372.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019880990.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling"
XP_019871218.2	5	Reactome: R-HSA-2206305;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695	"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Neutrophil degranulation"
XP_019864925.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_049825513.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019864656.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_019880137.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_019878625.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_019876089.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049826347.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019866927.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049823314.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_019868853.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019872279.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019878636.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049821683.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049820864.1	32	Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_019869421.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_019880336.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_049819577.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019871687.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_019869417.2	15	Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585	"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Oncogene Induced Senescence"
XP_019864576.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049825764.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824856.1	31	MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-5367;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-4381;MetaCyc: PWY-5994;MetaCyc: PWY-7746;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-5147;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWYG-321	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";""
XP_049821254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019877512.2	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_019869713.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_019873405.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_019869930.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049824860.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019869785.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019881120.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049818695.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_019870811.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049817239.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019870205.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049826028.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019871124.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049823499.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049823255.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049826346.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049818316.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_019872984.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_019871683.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-426496	"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs"
XP_019880665.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_019880383.2	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_019880767.2	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049821934.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-68877	"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase"
XP_049821959.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019880284.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_019868961.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019869763.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817904.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019876936.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1"
XP_019872331.2	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049819030.1	10	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6802952;Reactome: R-HSA-380270;Reactome: R-HSA-5576890;Reactome: R-HSA-5576893;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Signaling by BRAF and RAF fusions";"Recruitment of mitotic centrosome proteins and complexes";"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_019880957.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019873901.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049819351.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049822647.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_049818666.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases"
XP_049823476.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019867027.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_019878348.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_019866184.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_019871910.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019864560.2	6	Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization"
XP_049823046.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019880062.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019865450.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019869972.2	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_019873297.2	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_049824336.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049824268.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866345.1	9	KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049819099.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_019874747.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_019877626.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049822805.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_019867852.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019871035.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_019870188.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049824290.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_019865243.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_019874375.1	10	Reactome: R-HSA-2453902;Reactome: R-HSA-977225;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-975634;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;MetaCyc: PWY-7849	"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Purine metabolism";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Neutrophil degranulation";"Urate conversion to allantoin III"
XP_019871301.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049825033.1	20	Reactome: R-HSA-71403;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-75105;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-163765;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Neutrophil degranulation"
XP_049817856.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019880248.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049820803.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_019875751.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_019878777.2	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_019865839.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_019866466.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription"
XP_019873138.1	15	Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167158	"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex"
XP_049822002.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049826365.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_019871694.1	10	KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11	"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism"
XP_019870158.2	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_019872503.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_019868393.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019878656.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_019871799.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019871748.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049821264.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_019875092.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019866137.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019878093.2	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_019872039.2	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_049820015.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019880827.1	20	KEGG: 05165+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-166208;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Regulation of PTEN gene transcription";"PI3K-Akt signaling pathway";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Thermogenesis";"Macroautophagy";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Human immunodeficiency virus 1 infection";"mTOR signalling";"Regulation of TP53 Degradation";"Human cytomegalovirus infection"
XP_019870966.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes"
XP_019867288.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049821197.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049819849.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049823459.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019881568.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_019870201.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_019868579.2	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_049821473.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_019868477.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019880793.1	18	MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Plasmalogen degradation";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_049826740.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865957.2	5	Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_019864664.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049821840.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049817819.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_019869752.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019867731.2	1	Reactome: R-HSA-419771	"Opsins"
XP_019865321.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_019866600.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049825442.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-112382	"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex"
XP_049826050.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019879890.2	4	KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerol degradation I"
XP_019872287.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049820628.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049819766.1	7	MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;Reactome: R-HSA-71336;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism"
XP_049826205.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_019872923.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049822758.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821992.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049825959.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019876679.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_019870691.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049817146.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019871745.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_019879644.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019869573.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_019872288.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019867029.2	9	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation"
XP_049822761.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019871288.2	7	KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-73817	"Purine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis"
XP_049822296.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019877659.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019872142.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_019872671.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049821346.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019879533.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_019877928.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_019865049.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_049823223.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019871175.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019866098.2	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes"
XP_049818044.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_019868976.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_019865651.2	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_019875131.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019865770.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049825981.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_019871506.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_019873212.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019864544.2	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019864800.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049824099.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049824062.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049825892.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019866139.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-68877	"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase"
XP_019880459.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049825514.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_019865576.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_019873415.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049826517.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049817389.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290	"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation"
XP_019880570.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049823610.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019872449.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019866846.1	6	Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_049820004.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
XP_019866389.2	8	KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-5154	"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049823333.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049825624.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049822300.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049818003.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049820513.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049817106.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049819423.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4	"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PC";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Stigma estolide biosynthesis";"Ether lipid metabolism"
XP_019870573.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049824175.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019877181.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_049818946.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_019868963.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049821761.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049820228.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA"
XP_019879181.2	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability"
XP_019881357.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019874606.2	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_019877349.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049824907.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_019868392.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868994.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019881544.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817303.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049825643.1	3	Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117	"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis"
XP_019875636.1	9	MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_019868229.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_019865530.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_019880700.2	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049824171.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019869057.1	7	MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6470;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13	"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis"
XP_019865253.2	3	KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism"
XP_019868617.1	4	Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination"
XP_049817619.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_019874421.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019869558.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049823479.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049821966.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019877247.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_019876139.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049825862.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019869687.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019876540.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049823799.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049817326.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019877015.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276	"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Degradation of DVL";"Separation of Sister Chromatids";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_019867371.2	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_019867058.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system"
XP_019870480.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818162.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049825900.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019877620.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049819379.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244	"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ion homeostasis";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation"
XP_019869337.2	22	Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway"
XP_049819796.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049818752.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049821155.1	23	Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-392851	"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (q) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor"
XP_049826797.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049824630.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_019872902.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049817549.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_019871888.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-6703;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;Reactome: R-HSA-1474151	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049817684.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019874047.2	16	MetaCyc: PWY-6886;MetaCyc: PWY-8004;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003	"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol"
XP_049820719.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826746.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_019865124.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-7233;KEGG: 00130+2.1.1.222+2.1.1.64	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_019866210.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019871206.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472	"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_019874822.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019878036.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019874362.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_019870303.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_049826637.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049817809.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_019872156.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049820675.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
YP_009437732.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_019870619.2	52	Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276	"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_019877122.2	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
XP_049821800.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049821833.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_049819569.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049824545.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68952	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation"
XP_019880947.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049821368.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049825600.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824012.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868582.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_019873397.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049826427.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_019874624.2	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_019867571.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049824746.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049817065.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049818808.1	5	Reactome: R-HSA-8948216;Reactome: R-HSA-3214841;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"PKMTs methylate histone lysines";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_049818175.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_019871339.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049820654.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_019873825.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019872300.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019869265.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_019881345.1	12	Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9619483	"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Macroautophagy";"Thermogenesis";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs"
XP_019873338.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049819383.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324	"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_049824864.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_019871474.2	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_019871084.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049822574.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019865106.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019869982.2	7	Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049822678.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_019871682.1	52	Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_019881029.1	18	Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Synthesis of PA";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_049819824.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019874786.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_019868072.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049818352.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049821657.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049819427.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049826006.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_019876776.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019878547.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_019870387.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_019873770.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019875624.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049823569.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019872832.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_019880073.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019879295.2	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019865966.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049826704.1	5	MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism"
XP_019866773.2	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049822848.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019865114.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019869329.2	22	Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-68877	"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase"
XP_049825106.1	6	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049820278.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049819413.1	14	MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Synthesis of PC";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
XP_019866968.2	4	Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_049818749.1	10	KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_019870519.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_019875854.2	57	Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695	"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Neddylation";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation"
XP_019881620.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019877709.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_049818025.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049825996.1	9	MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-8004	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Entner-Doudoroff pathway I"
XP_049821359.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049819044.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_049822750.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049823464.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism"
XP_019867499.1	6	MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049817668.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_019876202.2	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_019873947.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019873639.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019874714.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049824228.1	19	Reactome: R-HSA-70263;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37	"Gluconeogenesis";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism"
XP_019866560.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_019875278.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_019877982.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019871105.2	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_019866829.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019875470.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019878554.1	3	Reactome: R-HSA-8953750;Reactome: R-HSA-427389;Reactome: R-HSA-73772	"Transcriptional Regulation by E2F6";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape"
XP_019871198.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049824909.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049825720.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_019867228.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-5619078;Reactome: R-HSA-727802	"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars"
XP_019877841.2	52	Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-5617472	"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_019865381.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019867825.2	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049824092.1	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_049820473.1	8	KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis"
XP_019866144.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568	"Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase"
XP_019868919.2	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049819425.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019873504.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_019878457.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049822906.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019868368.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_049819511.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049824197.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_019876901.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049820403.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_019873294.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_019875881.2	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_019868537.1	12	Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383	"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_019879080.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_019869093.2	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049819365.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019872644.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049820890.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_019877252.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049825028.1	10	Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722	"Ub-specific processing proteases";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"HATs acetylate histones";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex"
XP_019872083.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_019873717.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_019864857.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019871876.2	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_019870870.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_019873444.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049825582.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049826392.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049821159.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049824475.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019865583.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049818922.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019874712.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049824835.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019869751.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049820936.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019868018.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049821960.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019869947.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049821865.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_019866781.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_019881792.2	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019875540.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019873236.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_019867299.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049817401.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049817741.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019867891.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_019870866.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_019881113.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_019869613.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_019880087.1	11	MetaCyc: PWY-5123;MetaCyc: PWY-922;MetaCyc: PWY-6383;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102;MetaCyc: PWY-7560;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-6859	"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"All-trans-farnesol biosynthesis"
XP_019873494.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181	"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB"
XP_019876019.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_019871491.1	1	Reactome: R-HSA-419771	"Opsins"
XP_019878571.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049818769.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_049825937.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_019869407.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism"
XP_019875925.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049823648.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049824637.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019868273.2	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803211	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_019874814.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049825746.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_019874566.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049821655.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049819935.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049821977.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408	"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism"
XP_049824106.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_019877713.2	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_049823765.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049823518.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049818652.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_019864672.2	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049824738.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049821098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019865460.1	7	Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586	"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_049822398.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049817806.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049824217.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_019873874.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049821990.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295	"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation"
XP_019868588.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_019878186.2	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_019869601.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049818755.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_019865869.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_019879321.2	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;MetaCyc: PWY-7980	"Photosynthesis";"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ATP biosynthesis"
XP_019873869.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049826607.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049826682.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019870634.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019880453.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049824697.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049819943.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_019869802.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_019874327.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019871412.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_019876119.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019867741.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049820367.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_019880212.2	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_019874419.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049818174.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019872880.2	4	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_019878680.2	6	KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017	"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_019881760.2	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049824359.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_019868380.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019871361.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019874361.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049825975.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049821527.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049822687.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049819472.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049819891.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049821759.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049826454.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049825857.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049821537.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049818320.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-191859	"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly"
XP_049821026.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700	"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_019870617.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049823959.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049823667.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_019873769.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049819890.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019875157.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt"
XP_049824859.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817663.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049817739.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049824477.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049824534.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019875067.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166	"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2"
XP_019864942.1	18	KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115	"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Arginine biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_019873963.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019870925.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_019868146.1	6	KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_049819312.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_019869948.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049823581.1	7	MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;Reactome: R-HSA-70221	"Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)"
XP_019873683.2	17	MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7226	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_019880795.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_019874280.2	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049819684.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019875552.2	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049824278.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019865972.2	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_049825110.1	9	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)"
XP_019869584.1	179	Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-9033241;Reactome: R-HSA-975144;Reactome: R-HSA-3134975;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-2559582;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-977225;Reactome: R-HSA-5678895;Reactome: R-HSA-192823;Reactome: R-HSA-3785653;Reactome: R-HSA-450302;Reactome: R-HSA-975956;Reactome: R-HSA-6804757;Reactome: R-HSA-5675221;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-937041;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-9615710;Reactome: R-HSA-5689603;Reactome: R-HSA-69231;Reactome: R-HSA-2173791;Reactome: R-HSA-6782135;Reactome: R-HSA-975110;Reactome: R-HSA-450408;Reactome: R-HSA-6783310;Reactome: R-HSA-450321;Reactome: R-HSA-5205685;Reactome: R-HSA-110312;Reactome: R-HSA-400253;Reactome: R-HSA-168927;Reactome: R-HSA-187577;Reactome: R-HSA-5675482;Reactome: R-HSA-4608870;Reactome: R-HSA-174490;Reactome: R-HSA-901032;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-2979096;Reactome: R-HSA-5656169;Reactome: R-HSA-168928;Reactome: R-HSA-72689;Reactome: R-HSA-8939902;Reactome: R-HSA-532668;Reactome: R-HSA-6781823;Reactome: R-HSA-209543;Reactome: R-HSA-5696397;Reactome: R-HSA-936964;Reactome: R-HSA-5357956;Reactome: R-HSA-2173796;Reactome: R-HSA-5696400;Reactome: R-HSA-8854050;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-445989;Reactome: R-HSA-5696394;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-2559585;Reactome: R-HSA-5362768;Reactome: R-HSA-8856828;Reactome: R-HSA-1169408;Reactome: R-HSA-8863795;Reactome: R-HSA-8875360;Reactome: R-HSA-110314;Reactome: R-HSA-201681;Reactome: R-HSA-6791226;Reactome: R-HSA-8849469;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-209560;Reactome: R-HSA-2691232;Reactome: R-HSA-75815;Reactome: R-HSA-975957;Reactome: R-HSA-9645460;Reactome: R-HSA-5689896;Reactome: R-HSA-175474;Reactome: R-HSA-5610780;Reactome: R-HSA-72706;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-156827;Reactome: R-HSA-1358803;Reactome: R-HSA-5689901;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-5654727;Reactome: R-HSA-5689877;Reactome: R-HSA-162588;Reactome: R-HSA-2559580;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-9637628;Reactome: R-HSA-8866654;Reactome: R-HSA-5610783;Reactome: R-HSA-2672351;Reactome: R-HSA-2644606;Reactome: R-HSA-1295596;Reactome: R-HSA-174113;Reactome: R-HSA-2173788;Reactome: R-HSA-4641257;Reactome: R-HSA-69541;Reactome: R-HSA-9613829;Reactome: R-HSA-6781827;Reactome: R-HSA-180534;Reactome: R-HSA-1236382;Reactome: R-HSA-2871837;Reactome: R-HSA-9633012;Reactome: R-HSA-174084;Reactome: R-HSA-6807004;Reactome: R-HSA-983168;Reactome: R-HSA-1253288;Reactome: R-HSA-975163;Reactome: R-HSA-5658442;Reactome: R-HSA-4641263;Reactome: R-HSA-5668541;Reactome: R-HSA-5654733;Reactome: R-HSA-9010553;Reactome: R-HSA-2565942;Reactome: R-HSA-5654726;Reactome: R-HSA-912631;Reactome: R-HSA-2894862;Reactome: R-HSA-8852276;Reactome: R-HSA-1799339;Reactome: R-HSA-4641258;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-917729;Reactome: R-HSA-174154;Reactome: R-HSA-3769402;Reactome: R-HSA-156902;Reactome: R-HSA-8951664;Reactome: R-HSA-6804760;Reactome: R-HSA-5357905;Reactome: R-HSA-1169091;Reactome: R-HSA-5654732;Reactome: R-HSA-349425;Reactome: R-HSA-5684264;Reactome: R-HSA-179409;Reactome: R-HSA-69601;Reactome: R-HSA-917937;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-2122948;Reactome: R-HSA-937072;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-937042;Reactome: R-HSA-110320;Reactome: R-HSA-9014325;Reactome: R-HSA-5610785;Reactome: R-HSA-9013507;Reactome: R-HSA-9013973;Reactome: R-HSA-6782210;Reactome: R-HSA-937039;Reactome: R-HSA-8876493;Reactome: R-HSA-5687128;Reactome: R-HSA-3322077;Reactome: R-HSA-5655862;Reactome: R-HSA-2173795;Reactome: R-HSA-69017;Reactome: R-HSA-9646399;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-182971;Reactome: R-HSA-205043;Reactome: R-HSA-5676590;Reactome: R-HSA-168638	"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Peroxisomal protein import";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of innate immune responses to cytosolic DNA";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Senescence-Associated Secretory Phenotype (SASP)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Amyloid fiber formation";"Defective CFTR causes cystic fibrosis";"Viral mRNA Translation";"Myoclonic epilepsy of Lafora";"activated TAK1 mediates p38 MAPK activation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of TP53 Degradation";"Negative regulation of MAPK pathway";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"IKK complex recruitment mediated by RIP1";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Late endosomal microautophagy";"UCH proteinases";"Cyclin D associated events in G1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Dual incision in TC-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Fanconi Anemia Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Pink/Parkin Mediated Mitophagy";"Translesion synthesis by REV1";"Circadian Clock";"TICAM1, RIP1-mediated IKK complex recruitment";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of necroptotic cell death";"Asymmetric localization of PCP proteins";"Membrane binding and targetting of GAG proteins";"ER Quality Control Compartment (ERQC)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Termination of translesion DNA synthesis";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Formation of a pool of free 40S subunits";"Regulation of RUNX2 expression and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of TC-NER Pre-Incision Complex";"p75NTR recruits signalling complexes";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TNFR1-induced NFkappaB signaling pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Dual Incision in GG-NER";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"DNA Damage Recognition in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Oncogene Induced Senescence";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Clathrin-mediated endocytosis";"ISG15 antiviral mechanism";"Downregulation of ERBB2 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Recognition of DNA damage by PCNA-containing replication complex";"TCF dependent signaling in response to WNT";"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NF-kB is activated and signals survival";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Ubiquitin-dependent degradation of Cyclin D";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Alpha-protein kinase 1 signaling pathway";"Ovarian tumor domain proteases";"Assembly Of The HIV Virion";"Degradation of GLI1 by the proteasome";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Downregulation of ERBB2:ERBB3 signaling";"Metalloprotease DUBs";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Negative regulation of FGFR2 signaling";"Josephin domain DUBs";"Budding and maturation of HIV virion";"Oxidative Stress Induced Senescence";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Modulation by Mtb of host immune system";"E3 ubiquitin ligases ubiquitinate target proteins";"Degradation of GLI2 by the proteasome";"Stimuli-sensing channels";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Spry regulation of FGF signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downregulation of TGF-beta receptor signaling";"Degradation of AXIN";"Stabilization of p53";"Chaperone Mediated Autophagy";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Vpu mediated degradation of CD4";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"FCERI mediated NF-kB activation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of MET activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB4 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of RAS by GAPs";"Regulation of FZD by ubiquitination";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of FGFR4 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of FGFR1 signaling";"Regulation of signaling by CBL";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SRP-dependent cotranslational protein targeting to membrane";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"APC/C:Cdc20 mediated degradation of Securin";"Deactivation of the beta-catenin transactivating complex";"Peptide chain elongation";"Neddylation";"Regulation of TP53 Activity through Methylation";"Regulation of TNFR1 signaling";"Activation of NF-kappaB in B cells";"Negative regulation of FGFR3 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Iron uptake and transport";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Activated NOTCH1 Transmits Signal to the Nucleus";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"IRAK2 mediated activation of TAK1 complex";"Translesion Synthesis by POLH";"TICAM1,TRAF6-dependent induction of TAK1 complex";"GLI3 is processed to GLI3R by the proteasome";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"TICAM1-dependent activation of IRF3/IRF7";"Gap-filling DNA repair synthesis and ligation in TC-NER";"IRAK1 recruits IKK complex";"InlA-mediated entry of Listeria monocytogenes into host cells";"MAPK6/MAPK4 signaling";"Glycogen synthesis";"Translesion synthesis by POLK";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"CDK-mediated phosphorylation and removal of Cdc6";"Aggrephagy";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"EGFR downregulation";"NRIF signals cell death from the nucleus";"NIK-->noncanonical NF-kB signaling";"NOD1/2 Signaling Pathway"
XP_019876764.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049819328.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_019870749.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049820267.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_019865328.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049822962.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049821653.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_019864597.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019878794.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049820311.1	10	Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-2894862	"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_019875846.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_019877840.1	52	Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-167246;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-77075;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Chain Elongation";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_019875277.2	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049818452.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142	"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins"
XP_049820659.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049819315.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_019872948.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049821311.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019869976.2	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_019874761.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049821324.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019871000.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_019873462.2	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5221030	"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA"
XP_019871760.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_019865115.2	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_019873112.2	12	Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells"
XP_019865667.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_019876166.2	8	Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
XP_019872843.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019875981.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049825322.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy"
XP_019866037.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_019877684.2	3	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_049823997.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_019877951.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-69205;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"One carbon pool by folate"
XP_049817931.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019880663.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824582.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049823336.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019871847.2	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-114608	"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation"
XP_019872114.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_049826720.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_019881586.2	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049818642.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_019880845.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism"
XP_019874575.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049817230.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_019870300.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-6783310;Reactome: R-HSA-3371511;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5696395	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Fanconi Anemia Pathway";"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"Meiotic recombination";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Formation of Incision Complex in GG-NER"
XP_019867791.2	16	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049826214.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_049819591.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049825302.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_019877960.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049819026.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049817052.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049822572.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_019873619.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_019871802.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049820287.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_019866390.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_019869755.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_049825972.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049820592.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_049818693.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049823626.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_019880403.1	12	MetaCyc: PWY-5749;MetaCyc: PWY-7295;MetaCyc: PWY-6728;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-6969;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5744;MetaCyc: PWY-7854;KEGG: 00620+2.3.3.9;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-7294	"Itaconate degradation";"L-arabinose degradation IV";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"D-xylose degradation IV"
XP_019878383.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_019879079.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_019866426.2	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_019865562.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_019871906.2	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_049825320.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049824108.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_049820309.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013508	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_049822891.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_019872870.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_049825287.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049819162.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_019867969.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049823136.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_019876606.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019866140.2	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_019874658.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019869392.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049825349.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-9013973	"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7"
XP_019872327.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019871191.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049819515.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019874488.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019869812.2	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_019873892.2	33	Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638	"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins"
XP_019879730.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049826536.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049822484.1	18	KEGG: 00350+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1	"Tyrosine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Cysteine and methionine metabolism"
XP_049816961.1	4	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation"
XP_049819638.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019871919.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019872064.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019878626.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019873459.2	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_049819091.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019869450.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_019877492.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049821762.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_019866155.1	10	Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6362;Reactome: R-HSA-983231;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;Reactome: R-HSA-1855204;MetaCyc: PWY-6365;MetaCyc: PWY-4661	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_049826163.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049820387.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049822573.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_019871636.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226	"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049818631.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_049821353.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049822714.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083	"ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions"
XP_019875193.2	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7254	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)"
XP_049817293.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019880688.2	27	Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333	"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049817483.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019871818.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_019874707.2	16	Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049822330.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702	"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands"
XP_049821906.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_049824857.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019864550.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019871786.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411	"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)"
XP_019879588.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049824529.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_049820084.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019869327.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019867487.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049819882.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_019871720.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation"
XP_049818244.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_019869000.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019873660.2	14	KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_019865705.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_049821335.1	15	Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-195253	"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex"
XP_049823502.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049821242.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_019874559.2	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019871877.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_019877068.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_019868572.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049818281.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019866721.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049822267.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019873440.1	6	Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077	"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_019872390.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_019880391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049818180.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_019870595.2	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_019876009.2	8	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling"
XP_049823480.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019866103.1	6	MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12	"Stachyose degradation";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_019874586.2	20	MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7726;MetaCyc: PWY-7338	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_049822751.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049817384.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049826040.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_049819132.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_019869188.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_019871325.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_019867600.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049817412.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019868991.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_019865624.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_019866479.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_019873197.1	14	MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5080	"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I"
XP_019879387.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049824912.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019873920.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_019874957.2	9	Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-9656255;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Defective OGG1 Substrate Binding";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049817240.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049822601.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049821160.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019873380.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_049821822.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049825469.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_019872278.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_019880099.2	15	Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938	"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)"
XP_019870023.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_019878487.2	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_019868894.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_019872174.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_049819469.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_049817147.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_049817199.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049822480.1	18	Reactome: R-HSA-8953750;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938	"Transcriptional Regulation by E2F6";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)"
XP_019865219.2	24	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Aggrephagy";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors"
XP_049824216.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_019875802.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049824861.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019873168.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_019865863.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019880147.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_019870272.1	10	MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344	"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"Galactose catabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis"
XP_049819793.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019871073.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049824544.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049817480.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019867572.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_019874031.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049819073.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049826348.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019876172.1	4	KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_019870850.2	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_019874722.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049823583.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25	"Neutrophil degranulation";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation II";"Starch and sucrose metabolism"
XP_049821030.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_019870574.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_019871026.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049822246.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019866206.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019875282.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820922.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Neutrophil degranulation"
XP_019866498.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_019871061.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049823702.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019880481.2	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_019866850.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_019881474.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865796.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049817636.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049819934.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_019881573.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752	"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated"
XP_049825050.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300	"DNA methylation";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA"
XP_019877457.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_019878076.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_019873472.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049821011.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049824192.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049819381.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors"
XP_049826305.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019866803.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019870863.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049823219.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049824523.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_019866055.1	7	Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_019880487.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019864878.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049826156.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019879954.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049818893.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019864961.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_049818923.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019864592.2	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_019874124.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049825930.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019875334.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019875755.2	25	Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-380270;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of mitotic centrosome proteins and complexes";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recycling pathway of L1";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_019867719.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_019869907.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_019866852.1	6	Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049825682.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_019873628.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049824446.1	18	MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG"
XP_019870812.2	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_019865275.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_019870933.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019876140.2	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049822762.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019867679.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_049821097.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818691.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019867605.2	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_019868509.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019876846.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_049820902.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_019866937.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019865802.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084	"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_019867162.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049823752.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019873006.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_019867529.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049819385.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_019880455.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_019881800.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019865191.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019880717.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019880931.1	29	Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-5696400	"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER"
XP_049824463.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_019876630.1	11	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human papillomavirus infection"
XP_049817172.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
XP_049825317.1	17	Reactome: R-HSA-1221632;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6796648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473	"Meiotic synapsis";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of DNA Repair Genes";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint"
XP_049821356.1	30	Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-2644606;Reactome: R-HSA-5610780;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2644607;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-174113	"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Iron uptake and transport";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Orc1 removal from chromatin";"Neddylation";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049818672.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
YP_009437741.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019874738.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049817394.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_019877049.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_019881510.1	9	MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12	"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms"
XP_049824552.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_019870542.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_019870199.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019877819.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049825308.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin degradation I (archaea)"
XP_019868036.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049817845.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019874169.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049819376.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_049820546.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_019872635.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_049818872.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049823434.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019877280.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019865707.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_019874244.1	5	Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation"
XP_019869531.2	8	Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_019871631.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_049818583.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_049818087.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817200.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_019872970.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019878299.2	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_019865347.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019867944.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049820280.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_019869994.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_019866468.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_019869352.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_049820539.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049819002.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_019869341.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049818846.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019871589.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019877804.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049817030.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_049822438.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019881668.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049819171.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824064.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019869054.1	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755579	"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_019868772.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_019871131.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049822935.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_019874376.1	10	Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;Reactome: R-HSA-975634;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;MetaCyc: PWY-7394	"Non-integrin membrane-ECM interactions";"Purine metabolism";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Neutrophil degranulation";"Urate conversion to allantoin I";"Retinoid metabolism and transport";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II"
XP_019867006.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_019871423.1	32	Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648	"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes"
XP_019869583.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019879605.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation"
XP_049821504.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049818930.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019866167.1	30	Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1170546;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-2644607;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-400253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783	"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Prolactin receptor signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome"
XP_019871911.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049820877.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049821785.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_019872754.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049817582.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049820962.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_019876354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019877636.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_019875078.2	6	MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_019877200.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049823513.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049826619.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019872237.1	5	Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;MetaCyc: PWY-7782	"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis"
XP_049826012.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856825	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis"
XP_019875038.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049819578.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_019869087.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019864929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019865302.2	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049821819.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_019875480.2	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_019874088.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_019875165.2	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_019865331.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049824617.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019881492.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019876483.1	8	KEGG: 00250+6.3.4.5;MetaCyc: PWY-5154;MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-5;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5	"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis";"Urea cycle";"Arginine biosynthesis"
XP_019866948.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049818021.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019871570.2	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation"
XP_019864886.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_049819877.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049824219.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049826393.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049823996.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events"
XP_019876935.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049820005.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
XP_019872684.1	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268;MetaCyc: PWY-6901	"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation"
XP_049817731.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019869937.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049824615.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019872164.2	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_019869654.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049817167.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049819453.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019877426.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_019865211.1	11	KEGG: 00564+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4	"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Ether lipid metabolism"
XP_019870171.2	6	Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;MetaCyc: PWY-6854	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)"
XP_049826534.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019867307.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049818688.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019867302.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049825079.1	31	MetaCyc: PWY-8049;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;MetaCyc: PWY-4381;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-5367;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6799;MetaCyc: PWY-5971;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-6519	"Pederin biosynthesis";"";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I"
XP_019867664.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049817166.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569	"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HCMV Early Events";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049817323.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_019869639.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_019867076.2	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_019881552.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_049818809.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_049819380.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-438066	"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049819926.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019874126.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049819593.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019873436.2	19	Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-202733	"Scavenging by Class H Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"VLDL assembly";"Chylomicron remodeling";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall"
XP_019877722.2	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019866429.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_019866812.1	16	Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_019867031.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_019877285.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049818118.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049819570.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049820751.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_019872404.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019867628.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation"
XP_049818440.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049819205.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019879470.1	2	Reactome: R-HSA-606279;Reactome: R-HSA-6783310	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway"
XP_019866763.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_019876040.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019870177.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049824565.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049826721.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_019881324.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049823739.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_019878015.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049824277.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019865610.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_019879302.1	5	Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751	"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Ub-specific processing proteases";"Degradation of AXIN";"Regulation of PTEN stability and activity"
XP_049820706.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism"
XP_049823461.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_049822820.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019874416.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049822638.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049822636.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_019875404.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_019880424.2	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019881872.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_019881703.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019869858.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049818103.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049824834.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019867927.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049822692.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_019864708.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_049824383.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019864522.1	5	MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_049818586.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_049821799.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049820705.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism"
XP_049821654.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_019870804.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019876859.2	8	Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
XP_019872690.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005	"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+"
XP_019881494.2	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_019877016.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_019870615.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049821633.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880	"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Ub-specific processing proteases"
XP_019866302.2	10	MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_019881725.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_019881609.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049825109.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019866632.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_019871022.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049826747.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_019867244.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019876978.2	13	KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184	"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049824269.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_019879962.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019877622.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_019866722.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019877504.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019873110.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_019867887.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049824380.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049821975.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049826041.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_019876835.1	26	Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-8866654;Reactome: R-HSA-1362277;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-4615885;Reactome: R-HSA-6804114;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"G1/S-Specific Transcription";"Polymerase switching";"E3 ubiquitin ligases ubiquitinate target proteins";"Transcription of E2F targets under negative control by DREAM complex";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"SUMOylation of DNA replication proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_019869524.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_019880550.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6798695	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation"
XP_019865574.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_019871440.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817604.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_019881431.1	12	MetaCyc: PWY-3801;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9	"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_019878291.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019880329.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_019880647.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019870637.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049817548.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049817160.1	10	MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061	"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I"
XP_019869107.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_019873219.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049819348.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_019876200.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_019881491.2	11	Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-400253	"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock"
XP_019868271.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049821290.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_019868583.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049817068.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_019870894.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019872773.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_019866795.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_019873755.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019874649.2	6	Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731	"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_049825960.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019870632.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019864822.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5685938	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"HDR through Single Strand Annealing (SSA)"
XP_049820870.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049826031.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019878855.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019873233.2	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260	"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_019871085.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_019872768.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_019875280.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_019874961.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_049817655.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019880050.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Aggrephagy";"RHO GTPases Activate Formins"
XP_049822802.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_019877991.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049820920.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_019867695.2	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019876138.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane"
XP_049818522.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019877651.2	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_019876873.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-69205	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription"
XP_049821976.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_049822915.1	3	Reactome: R-HSA-71403;KEGG: 00430+1.4.1.1;KEGG: 00250+1.4.1.1	"Citric acid cycle (TCA cycle)";"Taurine and hypotaurine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_019868693.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049817392.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049821472.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049823526.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049821687.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_019865232.2	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization"
XP_019877065.2	14	MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Plasmalogen degradation";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_019875326.1	17	MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7187	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_019874741.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_019866268.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019875169.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049824053.1	11	MetaCyc: PWY-6999;Reactome: R-HSA-74259;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;Reactome: R-HSA-8851680	"Theophylline degradation";"Purine catabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Purine metabolism";"Butyrophilin (BTN) family interactions"
XP_019866100.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049817553.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019865192.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049818513.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019881900.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_049822859.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_049823227.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049820802.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019872496.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_019867396.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049819583.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049820470.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_049824281.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_019880980.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049817127.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049822302.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019874430.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049819068.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_019876547.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019875893.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_019865425.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_019871795.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049818117.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049817936.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837	"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation"
XP_049824107.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_019873986.2	4	Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane"
XP_019866515.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019867618.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Aggrephagy";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion"
XP_019865522.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049824748.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019881922.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049818496.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049825988.1	9	KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;MetaCyc: PWY-6146	"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Gluconeogenesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_019874133.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049826641.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049823855.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821156.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049819056.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_019879324.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049824765.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019876091.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818527.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_019881437.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_049821492.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019881651.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_049818482.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019877650.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049824094.1	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_019866868.2	11	Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642	"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling"
XP_019870539.1	32	Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-112382	"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex"
XP_019870215.2	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"MASTL Facilitates Mitotic Progression";"PI3K-Akt signaling pathway"
XP_049825803.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
YP_009437729.1	7	KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-5083;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;Reactome: R-HSA-611105;MetaCyc: PWY-4302	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Fe(II) oxidation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)"
XP_049824429.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049818569.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019866606.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_019864628.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids"
XP_019873739.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_019880131.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_019869090.2	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_049821347.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019870795.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820826.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049821757.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_019877289.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049817373.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049822265.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019867583.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019869504.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019877503.2	7	Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;Reactome: R-HSA-1483191	"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Synthesis of PC"
XP_019880205.2	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_019876685.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049822972.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019871905.2	3	Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation"
XP_049825368.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_019869856.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019874269.2	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_019872505.2	19	Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888	"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class B Receptors";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly"
XP_019868580.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019880987.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049823466.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049819880.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_019871723.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019866488.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_019869729.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019874927.2	5	KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049817771.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019866298.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049821756.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_019869878.2	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_019873155.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019881564.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049825845.1	26	Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158	"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_049826092.1	6	Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049824084.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019872358.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4	"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism"
XP_019872667.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019869500.2	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049823501.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049817865.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019876997.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049822606.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events"
XP_019875625.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_019881738.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049822567.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019873336.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane"
XP_019869323.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019879876.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049819344.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807	"T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling"
XP_019866192.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019871230.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049824806.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049820308.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_019881699.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019877001.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019865847.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019870630.2	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_019871122.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049823628.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049818617.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660	"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway"
XP_049818826.1	12	Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_049822545.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049824198.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_019868280.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_019871522.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019875110.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019876731.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_019878594.2	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_049826502.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_049821624.1	1	Reactome: R-HSA-445355	"Smooth Muscle Contraction"
XP_019871039.2	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_049820917.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle"
XP_019871411.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_019872294.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019872370.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_019867530.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049824728.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049821205.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049824444.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482788	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC"
XP_049826523.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_019871038.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049816945.1	10	MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism"
XP_049823696.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019869534.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019870802.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049824710.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_019881650.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis"
XP_049825220.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_049826613.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049824196.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049822980.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_049818161.1	17	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-2467813;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9022692;Reactome: R-HSA-174178;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-141444	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"RHO GTPases Activate Formins";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Separation of Sister Chromatids";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Regulation of MECP2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human papillomavirus infection";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049818460.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_019881575.1	37	Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-9639288;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-204005;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-983170;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-2132295	"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"Amino acids regulate mTORC1";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"COPII-mediated vesicle transport";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"MHC class II antigen presentation"
XP_019880739.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049826353.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_049818023.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-8953750	"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6"
XP_019881680.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019865837.2	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_019868589.2	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_019880623.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_019871898.1	13	Reactome: R-HSA-196836;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-4061	"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I"
XP_049819079.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019875999.1	58	Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5689901;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276	"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"Metalloprotease DUBs";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_019877082.2	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464	"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins"
XP_049822786.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_019871041.2	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_019880143.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_049820943.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821685.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_019881261.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049818632.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases"
XP_049817803.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_019867702.2	3	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_019867751.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_019878521.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049817081.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_019873776.2	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_019864995.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019878460.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_019881380.1	12	MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Pentose and glucuronate interconversions"
XP_049822800.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_019867649.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019876879.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_019864545.2	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049819089.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019881543.2	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_019864973.1	21	MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7224;KEGG: 00730+2.7.4.3	"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Thiamine metabolism"
XP_049822634.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824289.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_019876156.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_019868140.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019877014.1	18	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_019876080.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049823247.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019871209.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_019869073.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G"
XP_049826506.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_049819539.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_049817734.1	7	MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205	"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes"
XP_019877026.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_019869166.2	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049817369.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049819247.1	6	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049820023.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_019867659.2	6	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_019871737.2	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049825245.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049818909.1	7	KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456	"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylketonuria"
XP_019871327.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049819148.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049824801.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417	"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049824764.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049825098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019873299.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019868067.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019879410.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049826663.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818104.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049817444.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_019881767.2	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_049817664.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049820784.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_019866260.1	8	KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_019879616.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_049823467.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_019871979.2	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_019866270.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)"
XP_019871071.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019866312.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_019871981.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019867814.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049823633.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_019878639.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_019874851.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019871590.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019875808.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_019876137.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_019871758.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_049817441.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_019868575.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049824009.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049823262.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_019864846.1	11	Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-381;MetaCyc: PWY-6964	"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II"
XP_049821560.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019870197.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_019866341.1	9	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection"
XP_049825480.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049826436.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_019869098.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-426496	"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs"
XP_019868809.2	5	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_019881169.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049825092.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019868372.2	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_019881203.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA"
XP_049822817.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_019867764.2	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_019876188.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821612.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_019870649.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868044.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019866291.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_019877374.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_019868785.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019866484.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_019868563.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049819189.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049825307.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049826574.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_019868995.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019866215.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019877417.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049818681.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019866382.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049819572.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_019877632.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_019868134.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019871915.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049826479.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818046.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_019865872.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049818002.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019875062.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972	"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_019865358.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049826384.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_019865438.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019879014.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049820783.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_019872213.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049822936.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_019871141.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049823040.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019870193.2	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_049823690.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019875554.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_019874561.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_019870883.2	29	Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6781823	"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex"
XP_049825107.1	6	KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_019866483.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049823783.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049826669.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817808.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049817329.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049819787.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019865599.2	10	MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;Reactome: R-HSA-1989781	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"PPARA activates gene expression"
XP_019868724.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-373080	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)"
XP_019869546.1	9	Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356	"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_019867940.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019871880.2	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_019875059.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049823941.1	30	Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764	"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"Neddylation";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling"
XP_049825055.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Separation of Sister Chromatids";"G2/M Checkpoints";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin"
XP_019872841.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019865519.2	5	KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_049821134.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019867160.2	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049821677.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049821758.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_019874342.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_049826730.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019875414.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_019881888.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049817635.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049817691.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049817159.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_019877051.2	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_049817980.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049821767.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_049818753.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_019865145.2	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_019880089.2	32	Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-112382	"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex"
XP_019868655.2	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_019870299.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821193.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049820233.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019868066.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019873101.2	11	Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-72163;Reactome: R-HSA-9013695	"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_019864949.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_019876676.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_019868895.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826095.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019865909.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049826227.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019878427.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_019877597.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_019878152.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-3861;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Synthesis of GDP-mannose";"Fructose and mannose metabolism"
XP_019867122.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_019877730.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_019865874.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_019867030.2	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019864584.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-8939243;Reactome: R-HSA-2559580	"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence"
XP_049819075.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_019870552.2	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049824802.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049822813.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019880368.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049824221.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_019873868.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019870443.2	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_019868964.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_019872901.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_019874458.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_019869926.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049819764.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019881967.2	6	MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17	"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation"
XP_049826778.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019866597.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019880896.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_019875364.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049823363.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049817212.1	9	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_019878390.1	10	Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049824046.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049816962.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019868347.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Degradation of DVL";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin"
XP_049823698.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049824721.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"DNA methylation";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049824506.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049819404.1	14	Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782	"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis"
XP_019869227.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019874765.2	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_019881458.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049823654.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019871118.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019868039.2	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_019877251.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_019880649.2	42	MetaCyc: PWY-5136;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7216;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5177;MetaCyc: PWY-6944;MetaCyc: PWY-6883;MetaCyc: PWY-7726;MetaCyc: PWY-5109;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-6583;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7779	"Fatty acid beta-oxidation II (plant peroxisome)";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Fatty acid salvage";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Glutaryl-coa degradation";"Androstenedione degradation";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoate degradation";"alpha-Linolenic acid metabolism";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol I";"Geraniol degradation";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Phenylalanine metabolism";"Butanoate metabolism";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Propanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"2-methylpropene degradation";"Tryptophan metabolism";"Toluene degradation";"Methyl tert-butyl ether degradation"
XP_019864675.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019869629.1	14	KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-5497;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661-1	"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Photorespiration ";"Glycine betaine degradation I";"Folate transformations I";"Methane metabolism";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation II (mammalian)"
XP_019867368.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_019881774.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019874637.1	4	MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_049826731.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809	"Regulation of insulin secretion";"DAG and IP3 signaling";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization"
XP_019880468.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_049822596.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049818689.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019872109.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019868836.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049824628.1	5	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_019864831.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
XP_019868177.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-68877	"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Mitotic Prometaphase"
XP_049825093.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_019865351.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019867858.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_019878814.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_019870011.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019869326.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019864771.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019879479.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049825126.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019873637.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_019865447.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019871395.2	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_019869276.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019872391.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019869032.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019867775.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049820838.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_019870255.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_019868678.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_019874871.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway"
XP_019871835.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019864972.1	21	MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7224;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6	"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism"
XP_019869211.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019876256.2	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_019877031.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_019881411.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049823824.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019868406.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049817109.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_049825034.1	19	MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6728;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+2.3.3.8	"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes"
XP_019874397.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019878876.1	5	MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082	"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_019866977.1	3	Reactome: R-HSA-447043;Reactome: R-HSA-6798695;Reactome: R-HSA-3928664	"Neurofascin interactions";"Neutrophil degranulation";"Ephrin signaling"
XP_019880220.1	6	Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664	"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Neddylation"
XP_049825613.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049821991.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019865910.2	16	Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558	"RET signaling";"Costimulation by the CD28 family";"Rho GTPase cycle";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_019881264.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049820150.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_019873552.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049826176.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019869706.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_019866789.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049818685.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_019868918.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_019866044.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049824077.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids"
XP_019881423.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_019866378.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049826529.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_019870782.2	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_019877104.2	3	MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_049818943.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049825440.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049826377.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019876833.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049817688.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019867174.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_019878868.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049818105.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049825609.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_019875800.2	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_019880986.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_049825816.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_019871493.2	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049823495.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_019865368.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_019866565.2	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_019870122.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_019869350.1	3	KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_049823327.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049825251.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019879422.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049819069.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_019871486.1	7	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_049823220.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_019875074.1	8	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human papillomavirus infection"
XP_049825246.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_019866372.2	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_019873425.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_019865274.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_019865113.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049825481.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049823823.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019880997.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019867841.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019880541.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism"
XP_019869630.1	14	MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497	"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"Folate transformations I";"Methane metabolism";"Glycine betaine degradation I";"Cyanoamino acid metabolism";"Photorespiration ";"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)"
XP_049819303.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019881391.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019875826.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019877431.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049818673.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_019867024.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049824807.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019875606.2	29	Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-5696400	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER"
XP_019869088.2	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049822967.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_019878583.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279	"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)"
XP_019880923.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_019869053.1	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_019867363.2	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_019866153.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019880285.1	6	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_049822379.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019880953.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049821150.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049817364.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019871947.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049825979.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_019877706.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_019866768.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019869304.1	10	MetaCyc: PWY-7003;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1	"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Fructose and mannose metabolism"
XP_019878459.2	4	Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019872497.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_019873679.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_019871718.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657	"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes"
XP_049819163.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_019878621.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_019868045.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049822763.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_049823590.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049825771.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019878869.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049820545.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049825113.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_019864599.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817812.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_019870642.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019869656.2	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019869161.2	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_019873426.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_019869092.2	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049820566.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_019870257.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_019873087.2	19	Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423	"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Chylomicron clearance";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"LDL clearance";"VLDL clearance";"Scavenging by Class B Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron remodeling";"VLDL assembly"
XP_019865790.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019866950.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019873827.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049819304.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_019881201.2	6	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_019874447.1	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism"
XP_019867792.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049817681.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019867898.1	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_019880393.2	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_019866152.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019880118.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019868856.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019871241.1	57	Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-1169091	"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells"
XP_019864593.2	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_019874700.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049826037.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_049822602.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_019870565.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_019881209.2	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
YP_009437733.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049818674.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_019877814.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049823631.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049818442.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049825388.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_019870278.1	10	MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-3821	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"D-galactose detoxification"
XP_049826379.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019880815.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049818804.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3214841;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"PKMTs methylate histone lysines";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_019869175.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_019878016.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049824191.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_019867243.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049825978.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_019876916.2	16	Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049823009.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-428540	"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Activation of RAC1"
XP_019869010.2	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049826777.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019874000.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049826307.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_019875607.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_019879412.2	4	KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_019867838.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019870515.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049824465.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049819580.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
XP_019875559.1	10	MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-5030	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III"
XP_049817637.1	5	MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_019880569.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049823699.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019877404.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049821494.1	6	MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6907;Reactome: R-HSA-196819	"Thiamine salvage III";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism"
XP_049826477.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_019865296.2	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_019869159.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019877025.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling"
XP_049826025.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019877593.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049819581.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_019879549.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049820549.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019874030.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019866170.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049826723.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019870600.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_019873295.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019876426.1	16	Reactome: R-HSA-975138;Reactome: R-HSA-1257604;Reactome: R-HSA-1810476;Reactome: R-HSA-975110;Reactome: R-HSA-975871;Reactome: R-HSA-1236974;Reactome: R-HSA-3134963;Reactome: R-HSA-166058;Reactome: R-HSA-209543;Reactome: R-HSA-5603037;Reactome: R-HSA-975155;Reactome: R-HSA-5602498;Reactome: R-HSA-6811558;Reactome: R-HSA-5603041;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PIP3 activates AKT signaling";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 cascade initiated on plasma membrane";"ER-Phagosome pathway";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR5)";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling"
XP_019865189.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019870912.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019870531.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049824288.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_019877355.1	11	MetaCyc: PWY-6606;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5	"Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Pyrimidine metabolism";"Purine metabolism"
XP_019880392.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019867375.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019879454.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049817959.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_019877795.2	11	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript"
XP_019866232.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019880446.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_019873442.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019868741.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_049823757.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049819838.1	7	Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174	"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049826636.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019871129.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049821151.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049818443.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019868660.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049817241.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019880348.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_019873580.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_019870735.2	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_019871562.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_019880466.2	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_019874114.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049821712.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_019876046.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049825250.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049824335.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019867335.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_019881238.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049823304.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_019880449.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049823636.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_019871291.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049820248.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049825986.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_019880620.2	10	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Thermogenesis";"Recycling pathway of L1";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_019872059.1	57	Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-68949	"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin"
XP_049823649.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049822460.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628	"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_019870744.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019874971.2	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049821204.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049821144.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_049820146.1	9	Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-9656255;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine"
XP_019869708.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049825471.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_019874568.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049819963.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049819812.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_019880191.2	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_019869668.1	9	MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-4061	"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification I"
XP_049826505.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins"
XP_019866689.2	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049818900.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_019867247.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_019867060.2	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_019877002.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_019864712.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019868984.2	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049826706.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049819553.1	19	MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms"
XP_049821978.1	12	Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_019868126.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019869457.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_019870376.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019872545.2	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097	"mTOR signaling pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway"
XP_019868224.2	16	Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-983168	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019871207.1	7	Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription"
XP_049824037.1	6	KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;MetaCyc: PWY-5514;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation"
XP_019876899.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049818088.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049822921.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_019872881.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_019881481.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_019864858.1	6	Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049824354.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019865446.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049823630.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_019869889.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049818762.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049817343.1	7	MetaCyc: PWY-7185;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism"
XP_019870947.2	8	KEGG: 00790+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581;MetaCyc: PWY-5394;MetaCyc: PWY-6133;Reactome: R-HSA-209905;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2	"Folate biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism"
XP_049824918.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049817672.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049826496.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019880874.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824194.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049824898.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019880260.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019873404.1	18	MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7226	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_019873803.2	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_019865164.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_019873864.1	5	Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695	"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation"
XP_019869653.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019868377.2	6	KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2	"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation"
XP_019881257.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019875241.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019872407.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049818039.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049824509.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049817563.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_019874678.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019876739.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_019867770.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049821034.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_049826786.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049823279.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_019869061.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049824639.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_049826134.1	3	Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072	"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels"
XP_049820282.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_049823663.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_019873673.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019875119.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019869572.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019865292.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049818160.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_019875934.2	6	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_019877061.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_019865348.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_019881681.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049825386.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_019866804.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_019879561.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_049817365.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019874668.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049817415.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049825482.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049823570.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019867828.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049825364.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049824074.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_019871674.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_049824167.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019873714.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049822597.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049817362.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019874434.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049820286.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049822919.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049825037.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019867744.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019865185.2	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_019872570.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_049817888.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049826198.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_019869597.2	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_019873356.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_049825346.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_019867454.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049819921.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019864803.1	1	Reactome: R-HSA-419771	"Opsins"
XP_019865848.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019872086.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5	"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism"
XP_049822245.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019865195.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_019870172.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_019873548.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019877231.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_019880966.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049817007.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019868777.1	52	Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-749476	"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019878416.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_019869453.2	57	Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751	"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Separation of Sister Chromatids";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity"
XP_049821684.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_019881704.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_049820478.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_019867178.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_049821607.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction"
XP_019867617.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878	"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport"
XP_049821967.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_019879301.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019871679.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_049823067.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_019864887.2	7	MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-2161	"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate polyglutamylation"
XP_019873937.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049825077.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049823463.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA"
XP_019871307.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049822684.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049822465.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation"
XP_019877784.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation"
XP_019875524.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019874272.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049825321.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440	"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_049821733.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019877682.2	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049821798.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_019871771.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019875196.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_049818434.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_019873604.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_019865984.1	10	MetaCyc: PWY-7979;MetaCyc: PWY-7661;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;Reactome: R-HSA-162699;MetaCyc: PWY-7922;Reactome: R-HSA-4719377	"Protein O-mannosylation III (mammals, core M3)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_019873144.2	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_019879271.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049824847.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_019878958.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019867621.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_019870463.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_019868023.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049826391.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019875856.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_019879017.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049817440.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_049826362.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_019874976.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019880247.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049825690.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019877830.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019873324.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_019872776.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049817197.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049825948.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019864992.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049818824.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"mTOR signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection"
XP_049818445.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604	"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling"
XP_019875016.1	57	Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783	"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Separation of Sister Chromatids";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome"
XP_049819077.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism"
XP_019877719.1	14	Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665	"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells"
XP_019878750.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049824409.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_019877967.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_019867837.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019865907.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049821772.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049823828.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_019881862.2	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_049819563.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_019877531.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_019867204.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_019867270.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019868820.2	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049817678.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_019867524.1	5	Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"UCH proteinases";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_019881323.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_019874855.2	8	MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-7573	"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis"
XP_019876382.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019879705.1	19	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-8876725	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Protein methylation"
XP_019869029.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019867390.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_019881506.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049821790.1	16	Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB4";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_049826614.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049821987.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049819374.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_019872765.2	4	Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane"
XP_019876674.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049819316.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_019865479.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049823524.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049818670.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_019870761.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049825632.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985	"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose"
XP_019865463.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
XP_019866983.1	10	KEGG: 00650+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-5022;Reactome: R-HSA-916853;MetaCyc: PWY-6536;MetaCyc: PWY-6537	"Butanoate metabolism";"Propanoate metabolism";"4-aminobutanoate degradation I";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation V";"Degradation of GABA";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II"
XP_019865923.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049824001.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049819874.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049819040.1	10	Reactome: R-HSA-5576893;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5576890;Reactome: R-HSA-380270;Reactome: R-HSA-6802952;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Phase 2 - plateau phase";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Phase 3 - rapid repolarisation";"Recruitment of mitotic centrosome proteins and complexes";"Signaling by BRAF and RAF fusions";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049819070.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049820322.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_019869618.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049823922.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049823951.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019869686.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049825022.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_019875189.1	12	KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70171	"Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis"
XP_019881479.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049826160.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019869200.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049824554.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049825995.1	9	MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004	"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I"
XP_019870075.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049822613.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049823519.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049819808.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049821862.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_019866925.2	17	Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167242	"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049824489.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_019867763.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_019870259.2	14	MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_049820934.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019872045.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_019877373.2	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_019870059.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_019869340.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049820698.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9609690	"Recycling pathway of L1";"Aggrephagy";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events"
XP_019880444.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049824471.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019880242.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817332.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049824492.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_019873597.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-977225	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy";"Amyloid fiber formation"
XP_049826530.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049825309.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_049826585.1	2	Reactome: R-HSA-425986;Reactome: R-HSA-2672351	"Sodium/Proton exchangers";"Stimuli-sensing channels"
XP_019865031.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_019866712.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049826172.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019880289.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_019874815.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049824975.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019873050.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019868144.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019865573.1	4	MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_019867651.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049826540.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049821396.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049817372.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_019873082.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019870174.2	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_019865503.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_049820648.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049825797.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019878850.1	52	Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-112382	"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex"
XP_019870382.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_019871441.2	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid"
XP_049818720.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019872969.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019872506.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049826167.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049821050.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049825242.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2	"3-hydroxypropanoate cycle";"Carnitine metabolism";"Pyruvate metabolism";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Propanoate metabolism"
XP_049823353.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis"
XP_019877137.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049821692.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_019878385.2	40	Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-5617472	"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_019871483.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_019870016.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049826191.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049823240.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049820472.1	8	Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_019871094.2	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_019874808.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_049817935.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_019867395.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049825094.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049818771.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019877658.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_049820950.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_019873546.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019873310.1	42	MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6944;MetaCyc: PWY-6883;MetaCyc: PWY-7726;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6945;MetaCyc: PWY-5177;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-5136;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6863;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-6946;KEGG: 00627+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35	"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Fatty acid salvage";"Androstenedione degradation";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Glutaryl-coa degradation";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"2-methylpropene degradation";"Tryptophan metabolism";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Propanoate metabolism";"Methyl tert-butyl ether degradation";"Toluene degradation";"Fatty acid elongation";"Geraniol degradation";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Aminobenzoate degradation";"Benzoate degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"alpha-Linolenic acid metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Phenylalanine metabolism";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes"
XP_019870806.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_019875116.2	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1"
XP_019880290.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_049822010.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_019871475.1	18	MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1	"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Tyrosine metabolism"
XP_019874099.1	4	KEGG: 00230+3.6.1.17;Reactome: R-HSA-2393930;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685	"Purine metabolism";"Phosphate bond hydrolysis by NUDT proteins";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species"
XP_019864797.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_019864738.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes"
XP_049823254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049818498.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019870997.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_049824476.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019873106.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6361	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_049826612.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_049820165.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_019879135.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049824804.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049821253.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019880355.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019866810.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_019869013.2	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_019866864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019876310.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019865878.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019871366.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049821781.1	4	Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
XP_019876370.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049822194.1	17	MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes"
XP_019876372.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_019877193.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019867460.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019865251.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019879758.2	14	MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation"
XP_019876813.1	6	KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation"
XP_019872456.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_019866738.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049826039.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_019880315.2	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_019875528.1	11	Reactome: R-HSA-1660516;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-1660517;Reactome: R-HSA-109704;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137	"Synthesis of PIPs at the early endosome membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism"
XP_049817873.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_019872838.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049826027.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019873105.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-4661	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_019873280.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049826802.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408	"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation"
XP_049817322.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_049825441.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049822850.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049826705.1	5	KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-5523;MetaCyc: PWY-7863;Reactome: R-HSA-196843	"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism"
XP_019876293.2	10	Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880	"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Ub-specific processing proteases"
XP_049822463.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019881742.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049820412.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_019867114.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049821363.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569	"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_019872479.1	5	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_049824325.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049821993.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"MHC class II antigen presentation"
XP_049818948.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_019867301.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_019868292.1	5	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_019870377.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_019874533.2	9	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_019870482.2	9	Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367	"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_019868997.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_019869294.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049825559.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817383.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049818085.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
XP_049819603.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_019873899.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049822443.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_019872073.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_019874932.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_019872395.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019872060.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049824445.1	18	Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen degradation";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism"
XP_019875224.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019872357.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER"
XP_049821949.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049818080.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_019874125.2	6	Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_019871583.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049823553.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049817517.1	7	Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-140837	"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation"
XP_049817852.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_019881889.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049817243.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049822918.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_019876044.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_019872935.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_019879125.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049821255.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019868987.2	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049818604.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049822818.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_019881853.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049823627.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049819500.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_019874063.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_019875634.2	10	Reactome: R-HSA-203641;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-432722;Reactome: R-HSA-196025;Reactome: R-HSA-2132295;Reactome: R-HSA-166016	"NOSTRIN mediated eNOS trafficking";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"Golgi Associated Vesicle Biogenesis";"Formation of annular gap junctions";"MHC class II antigen presentation";"Toll Like Receptor 4 (TLR4) Cascade"
XP_019872335.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049822325.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state"
XP_049824501.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019869739.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019869036.2	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_019880765.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_019864615.2	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_019879736.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019874737.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049824722.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_049819456.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049824496.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049824982.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis"
XP_049821397.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049822621.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_019866788.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049821791.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019870805.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049823903.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17	"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism"
XP_019881984.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019874752.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_019880880.2	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_019874994.1	10	KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_019869154.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019868277.1	23	Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392451	"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma"
XP_019874440.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049821095.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818019.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049819871.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_019874193.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-191859	"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly"
XP_019878110.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818324.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_049826166.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_019870869.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049825725.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_019867655.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049820863.1	32	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6803529	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing"
XP_019865016.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019875434.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049817850.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_019880978.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019878057.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049821820.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_019873596.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy"
XP_019866274.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism"
XP_019870325.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_019867063.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049819794.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049825618.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019864977.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_019877059.2	14	KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409	"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_019874191.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362277	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex"
XP_019872797.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019876531.2	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_019880225.2	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049817181.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019875678.1	5	Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_049824183.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_019876158.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_049823894.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049824011.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049819386.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5685938	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)"
XP_019879360.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049818822.1	12	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Rho GTPase cycle";"Human papillomavirus infection";"mTOR signaling pathway"
XP_019866704.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_019870618.2	16	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019880408.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049819429.1	14	Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4	"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Stigma estolide biosynthesis";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_019867420.2	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes"
XP_049819172.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049817120.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_019864928.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_019877875.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019865668.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019865918.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019868632.2	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_049826476.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_019881924.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_019868057.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049821078.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_019873593.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049818791.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019870119.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019869627.1	14	MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497	"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"Methane metabolism";"Folate transformations I";"Glycine betaine degradation I";"Photorespiration ";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)"
XP_049826096.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019878160.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019869089.2	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1"
XP_049826121.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_019877625.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_019876816.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_019870206.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049826621.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019880219.2	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_019870466.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_049821601.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019866141.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_019874998.2	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049823883.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049823779.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049821491.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049821009.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_049821984.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049826026.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049826776.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019874487.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821441.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_019871234.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019868539.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_019869923.1	18	Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation"
XP_049821732.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_019880038.1	13	MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1	"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis"
XP_049826468.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_019869360.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019878154.1	14	Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690	"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)"
XP_019872781.1	40	Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-168325;Reactome: R-HSA-167200	"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_019880335.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049825112.1	4	Reactome: R-HSA-2995383;Reactome: R-HSA-6783310;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Fanconi Anemia Pathway";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_019872641.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation"
XP_019876095.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019876876.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049820361.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049819503.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex"
XP_049819325.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_019872909.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes"
XP_049822643.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_019876397.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_049826049.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019864946.2	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_019879371.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019880962.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019865244.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049826556.1	4	MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes"
XP_049819203.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049822882.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism"
XP_049825616.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049822229.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049819630.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019873890.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_019878378.2	56	Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome"
XP_019868822.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049823574.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019867121.1	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
XP_049823915.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019877522.2	1	MetaCyc: PWY-6938	"NADH repair"
XP_019872981.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4551638	"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins"
XP_019871293.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)"
XP_049821603.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019874388.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_049821608.1	5	Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471	"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_019880371.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_019866223.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019874510.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019873352.1	6	Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122	"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis"
XP_049819416.1	14	MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4	"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Synthesis of PC";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism"
XP_019867414.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049825940.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049826115.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049825105.1	6	Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382	"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_019867631.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399	"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy"
XP_019873835.1	7	MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363	"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_019871809.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome"
XP_019881507.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_019864627.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_019864692.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049825523.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049823751.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019873066.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019875401.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_019864882.2	13	KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2	"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes"
XP_049825653.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214	"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins"
XP_019876719.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019866067.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049826803.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944	"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2"
XP_019871813.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_019877515.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"G-protein activation";"G beta:gamma signalling through PLC beta";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor"
XP_049821263.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049818428.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049820729.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049822559.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049825253.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019868764.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019865577.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049823172.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019876809.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049819582.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_019877916.2	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_019864705.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_049818795.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_019874294.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049817485.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049819078.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_049826196.1	14	MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-399997;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-500657;KEGG: 00562+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Inositol phosphate metabolism"
XP_049820746.1	14	Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213	"Triglyceride biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE"
XP_019875572.1	10	MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030	"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III"
XP_019864824.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049821380.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes"
XP_049820321.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_019874475.2	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_049824520.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_019878038.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism"
XP_049824205.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_049822462.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397	"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049817270.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049823897.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019871845.2	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946	"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants"
XP_019869238.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_019880353.2	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_019870141.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049823403.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049818770.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049818397.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_019881972.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019881419.2	57	Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-532668;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-180585	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G"
XP_049819384.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-442982	"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_019881304.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019881211.2	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049821701.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049824195.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049826221.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_019866176.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049825929.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049821401.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049817194.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_019871519.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049819847.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049824619.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019880579.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_019868723.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_019865626.1	13	Reactome: R-HSA-6798695;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-5358346;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Neutrophil degranulation";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"HSF1 activation";"Josephin domain DUBs";"Aggrephagy";"Hedgehog ligand biogenesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ovarian tumor domain proteases";"Protein methylation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_019877721.2	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_019881064.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019867028.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_019867749.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_019867899.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049819243.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_019880316.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_019866539.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049825631.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049818043.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_019871063.2	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_019871185.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019869545.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049820945.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019877091.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562	"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neddylation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Separation of Sister Chromatids";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)"
XP_049817355.1	13	KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-2201;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3	"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes"
XP_049823695.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
YP_009437730.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049819875.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_019874784.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049822648.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049820944.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019869599.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310	"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway"
XP_019876702.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_019870564.2	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761	"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_019867893.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049826681.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049823425.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019879182.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049825459.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049818947.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049819199.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_019872080.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049821755.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_019866427.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_049821792.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049818349.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_019874522.2	33	Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531	"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins";"tRNA processing in the nucleus"
XP_019880865.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049826697.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019872900.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_019871651.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049823760.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_019874698.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049825896.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019872312.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019866686.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049817287.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_019867616.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation"
XP_019866166.1	30	Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-917937;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862	"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"Neddylation";"Orc1 removal from chromatin";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Iron uptake and transport";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049821997.1	21	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7221;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7205	"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation"
XP_019864710.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_019877069.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049819501.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_019872398.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_019874507.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_019871642.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049824977.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_049817315.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821613.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019874341.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_049818531.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049817785.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049818353.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_019869133.2	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049820885.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090	"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures"
XP_019864765.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049818806.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_019871688.2	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049821887.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019867521.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049818251.1	13	KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_019874496.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_019869595.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049822605.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway"
XP_019871948.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049817747.1	16	Reactome: R-HSA-9009391;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-512988	"Extra-nuclear estrogen signaling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"Rho GTPase cycle";"Costimulation by the CD28 family";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_019865797.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_019872926.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42	"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes"
XP_049824808.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019865560.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_019877803.2	12	MetaCyc: PWY-5855;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5873	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_049820684.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049817778.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049822395.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049824014.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019873379.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Neddylation";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling"
XP_049819104.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_019874748.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019881349.2	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_019865091.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019874018.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_019875502.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049817964.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-174437	"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand"
XP_019875477.2	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_019872656.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_019878828.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_019866425.2	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049820661.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_019871573.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_019868058.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Vitamin B6 metabolism"
XP_049821889.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_019875753.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_049821358.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_019875397.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_049820034.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Aggrephagy";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049823312.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_019865374.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019868584.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_019870651.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049826293.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004	"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I"
XP_019869056.1	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_019872597.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049819631.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019868695.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_019865552.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_019870369.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049818399.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_049823522.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_019869033.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049817291.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019875834.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121	"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI"
XP_019877371.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019874349.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_019865281.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049824522.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_019867131.2	7	MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane"
XP_049826197.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-434316;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-416476;MetaCyc: PWY-8052	"Ca2+ pathway";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis"
XP_019864558.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049826550.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_019876312.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019881566.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049819382.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_019874383.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_019878179.1	8	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049825128.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019881327.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_019864532.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019868763.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019870436.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_019881838.2	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049825542.1	9	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection"
XP_019865803.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_049819516.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019867475.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049824193.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_019871900.1	13	MetaCyc: PWY-7112;Reactome: R-HSA-196836;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1	"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Ascorbate and aldarate metabolism"
XP_019875231.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_019867906.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_019880540.2	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049821390.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_049817550.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_019870128.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049825347.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854	"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_049818312.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_019878860.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049822587.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_019869641.1	17	Reactome: R-HSA-141444;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-174178;Reactome: R-HSA-2500257;Reactome: R-HSA-9022692;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human papillomavirus infection";"SUMOylation of DNA replication proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Resolution of Sister Chromatid Cohesion";"Regulation of MECP2 expression and activity";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Separation of Sister Chromatids";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"RHO GTPases Activate Formins";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_019881189.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019867925.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_019877808.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_019875588.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049823697.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_019869321.1	30	KEGG: 04151+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-9614399;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-69202;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634638;Reactome: R-HSA-8876198;Reactome: R-HSA-69656;Reactome: R-HSA-6804758;KEGG: 05170+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-8948751;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-6804759;Reactome: R-HSA-199418;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8941332;Reactome: R-HSA-111447;Reactome: R-HSA-198693;Reactome: R-HSA-389513	"PI3K-Akt signaling pathway";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of localization of FOXO transcription factors";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Cyclin E associated events during G1/S transition";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RAB GEFs exchange GTP for GDP on RABs";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Acetylation";"Human immunodeficiency virus 1 infection";"AKT-mediated inactivation of FOXO1A";"Regulation of PTEN stability and activity";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Activity through Association with Co-factors";"Negative regulation of the PI3K/AKT network";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"RUNX2 regulates genes involved in cell migration";"Activation of BAD and translocation to mitochondria";"AKT phosphorylates targets in the nucleus";"CTLA4 inhibitory signaling"
XP_049824633.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019877079.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049824109.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_019866543.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_019867920.2	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_019866272.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)"
XP_049817692.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049820027.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019870635.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019870445.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_049821487.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383	"Glycolysis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_019876199.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_019874699.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956	"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049825532.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_019877411.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_019874476.2	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_019876723.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049820888.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_019870891.2	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_049817198.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049824179.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_019873013.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049818486.1	4	Reactome: R-HSA-164944;Reactome: R-HSA-2029482;Reactome: R-HSA-8849471;Reactome: R-HSA-4420097	"Nef and signal transduction";"Regulation of actin dynamics for phagocytic cup formation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFA-VEGFR2 Pathway"
XP_049817249.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER"
XP_049824448.1	7	MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352	"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis"
XP_049822550.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019871490.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019881776.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049821765.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_019866110.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis"
XP_049820667.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049823587.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_019881771.2	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_019865044.1	15	Reactome: R-HSA-8863795;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245	"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib"
XP_049820957.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049818031.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019874984.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_019866563.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_049826301.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_019866249.2	17	MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6608;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;MetaCyc: PWY-4202;Reactome: R-HSA-6798695	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine salvage";"Guanosine nucleotides degradation III";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation"
XP_049817584.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049826171.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049822552.1	10	Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_019869501.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_019881079.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_019873002.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049823589.1	5	MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-7761	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_049817849.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866428.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_019874174.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049823634.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_019866456.2	7	Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER"
XP_019880873.2	12	Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6613	"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Purine metabolism";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_019878173.1	12	MetaCyc: PWYG-321;MetaCyc: PWY-6728;KEGG: 00720+6.4.1.3;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-7384;KEGG: 00280+6.4.1.3;Reactome: R-HSA-71032;KEGG: 00640+6.4.1.3;KEGG: 00630+6.4.1.3;Reactome: R-HSA-196780	"";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Valine, leucine and isoleucine degradation";"Propionyl-CoA catabolism";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Biotin transport and metabolism"
XP_049821702.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049822893.1	13	Reactome: R-HSA-3000178;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"ECM proteoglycans";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Extracellular matrix organization";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Laminin interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_049818694.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_049817490.1	7	MetaCyc: PWY-7807;MetaCyc: PWY-6605;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;Reactome: R-HSA-6798695;MetaCyc: PWY-7805;Reactome: R-HSA-74217	"Glyphosate degradation III";"Adenine and adenosine salvage II";"Adenine salvage";"Purine metabolism";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation";"Purine salvage"
XP_019870225.2	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_019880305.2	19	Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938	"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class B Receptors";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Chylomicron assembly";"Chylomicron clearance";"Regulation of TLR by endogenous ligand"
XP_019865477.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_019873043.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049820633.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-7817;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5	"Synthesis of PA";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Synthesis of PG";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism"
XP_019880796.2	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_019864704.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_019880232.2	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_019865605.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049817779.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019876589.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2559582	"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)"
XP_019872311.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019880807.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049819587.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_019865971.2	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049824052.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6999;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;Reactome: R-HSA-8851680;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6608	"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Theophylline degradation";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation II";"Butyrophilin (BTN) family interactions";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III"
XP_019876041.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_019879434.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049821986.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-983189	"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Kinesins"
XP_049819329.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049823249.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_019869877.2	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_049825956.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_019875577.1	12	Reactome: R-HSA-3214847;Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-210744	"HATs acetylate histones";"RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_019873767.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049819843.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_019867410.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_019877889.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128	"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Downstream TCR signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Neddylation";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling"
XP_049817913.1	20	KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signalling";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"Macroautophagy";"Thermogenesis";"PI3K-Akt signaling pathway";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Human papillomavirus infection"
XP_019881549.2	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_019877342.1	5	Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221	"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway"
XP_019867687.1	9	KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2	"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis"
XP_019874975.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Macroautophagy";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_019875551.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049823250.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049824071.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_019866101.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_019865056.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;MetaCyc: PWY-7250;Reactome: R-HSA-947581	"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis"
XP_019872099.1	12	Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916	"MPS VII - Sly syndrome";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation"
XP_049821789.1	16	Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1236394;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604	"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB4";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling"
XP_019875025.2	7	Reactome: R-HSA-6782315;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"tRNA modification in the nucleus and cytosol";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049818255.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_019864770.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_019865342.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_049824813.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_049826102.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049825088.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-5663220;Reactome: R-HSA-6785631	"Neutrophil degranulation";"RHO GTPases Activate Formins";"ERBB2 Regulates Cell Motility"
XP_049822849.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049822107.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049826661.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019874479.2	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_019878233.2	8	Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638	"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins"
XP_049824260.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019874955.1	4	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation"
XP_049825392.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049825596.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049823348.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049819797.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019876755.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019865710.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_049822452.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_019881873.2	10	MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_049818114.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049819218.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_019878362.2	32	Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-113418	"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex"
XP_049825982.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_019881193.2	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019878316.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019878451.1	6	KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346	"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_019869148.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019873339.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049823608.1	21	MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7219;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7227	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"CMP phosphorylation";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_019868143.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_019877265.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_049825462.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019871794.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049818980.1	40	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-167242	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_019874548.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019875643.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-196025	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions"
XP_019881580.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_019866976.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962	"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex"
XP_019876648.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019870659.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019867425.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049824166.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019871396.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049826188.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019870368.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_019875943.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Macroautophagy";"Aggrephagy";"RHO GTPases Activate Formins"
XP_019878296.2	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_049821524.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_019871844.2	9	Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-114608	"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation"
XP_019867965.1	7	Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Folate biosynthesis";"Phenylalanine metabolism"
XP_049826190.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049824437.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839	"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE"
XP_049826787.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_049820694.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_019874254.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049826114.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049822640.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019873622.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_019869155.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_019881219.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049824960.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019868486.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049817551.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_019876432.2	18	Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-6796648;Reactome: R-HSA-8953750;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632	"G2/M DNA damage checkpoint";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional Regulation by E2F6";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis"
XP_049819928.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_019876043.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019869325.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049824484.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049821158.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049820130.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049821744.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_019864648.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_019869969.1	6	MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336	"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049825595.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019876450.2	18	MetaCyc: PWY-7383;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Arginine biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism"
XP_019874021.2	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_019865367.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_019874950.1	4	KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_019872539.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049824805.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049825692.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-8004	"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I"
XP_019875594.1	11	MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124	"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)"
XP_019874117.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_019871612.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_049826751.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019876584.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_019867370.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049824291.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_049822923.1	32	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_019864940.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019871592.2	27	Reactome: R-HSA-6803529;Reactome: R-HSA-975956;Reactome: R-HSA-191859;Reactome: R-HSA-72203;Reactome: R-HSA-77588;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-8851708;Reactome: R-HSA-159230;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-167152;Reactome: R-HSA-73856;Reactome: R-HSA-6807505;Reactome: R-HSA-159227;Reactome: R-HSA-72086;Reactome: R-HSA-159231;Reactome: R-HSA-674695;Reactome: R-HSA-77595	"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"snRNP Assembly";"Processing of Capped Intron-Containing Pre-mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Signaling by FGFR2 IIIa TM";"Transport of the SLBP Dependant Mature mRNA";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Termination";"RNA polymerase II transcribes snRNA genes";"Transport of the SLBP independent Mature mRNA";"mRNA Capping";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Pre-transcription Events";"Processing of Intronless Pre-mRNAs"
XP_019869478.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_019878215.2	4	Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_019877970.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049821262.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049823893.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019871469.2	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_019876177.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049817730.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_019869475.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_019875740.2	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_019871414.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049825146.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_019872171.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_049823520.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_019873592.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049820942.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019868391.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_019871617.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_019869030.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_019869144.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_019873153.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_019870603.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019868461.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049820494.1	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"RSK activation";"Thermogenesis";"Relaxin signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_049824553.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049821053.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049819629.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_019877157.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_049821256.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019869674.2	17	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-3270619;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"IRF3-mediated induction of type I IFN";"Meiotic recombination";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_019877215.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049821661.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049817292.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_019869939.1	22	MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_049826623.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_019870920.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_019877542.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049826161.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049819658.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_049817330.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019877943.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-69205;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"One carbon pool by folate"
XP_019864793.2	13	Reactome: R-HSA-196836;MetaCyc: PWY-7112;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-2261;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1	"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione conjugation";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism"
XP_019864774.2	14	Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-113418	"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex"
XP_049820714.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049818176.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_019873819.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Other types of O-glycan biosynthesis"
XP_019871727.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation"
XP_049817025.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019869824.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253	"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_019866087.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_049817368.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049820544.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049817462.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019875284.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_019870250.2	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_019871020.2	4	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes"
XP_019879274.1	32	Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_049817870.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019876765.2	7	Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049826380.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049819555.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_019879698.2	32	Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-72163;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-72086	"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"mRNA Capping"
XP_049817933.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049820915.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049821477.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_019873898.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_019876771.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019881298.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_019867626.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation"
XP_049818217.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049820646.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049825464.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049823226.1	20	MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7726;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7288;Reactome: R-HSA-9033241	"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import"
XP_019868020.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_049824270.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_019873918.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019865912.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049817777.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695	"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events"
XP_019870207.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_019874565.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_019879338.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049817689.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_019866273.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_049824777.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049822234.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019876424.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-432720	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Inhibition of membrane repair";"EGFR downregulation";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
XP_049826841.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019876986.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049825026.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_019872399.2	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049818515.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049825248.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_019874991.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_019881222.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019879845.1	19	MetaCyc: PWY-7205;Reactome: R-HSA-380270;MetaCyc: PWY-7187;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227	"CMP phosphorylation";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_019870734.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019869419.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_019870111.1	18	KEGG: 00620+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-71064;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;MetaCyc: PWY-5046;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71403	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Citric acid cycle (TCA cycle)"
XP_019864964.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049817574.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_019865540.2	5	Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-198323	"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol"
XP_049818222.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019866831.2	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_019868658.2	7	KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I"
XP_019865022.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes"
XP_019876151.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_019881265.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049818797.1	14	Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-561	"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_019868503.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_019876435.2	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_019869921.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049819061.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_019881228.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049823680.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019881607.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs"
XP_019872850.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_019866342.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_049825015.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_019879645.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019876912.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019874744.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_019868697.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_019866169.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019871952.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049823198.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049825617.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049820520.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049824726.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_049818086.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049821202.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049822752.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049817438.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_019866380.2	8	Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-6174	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)"
XP_019878248.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_049822658.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_019880588.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_019865372.1	34	Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505	"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes"
XP_019871729.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_019875482.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049824491.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_019869559.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_019872775.2	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
XP_019867474.2	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049819757.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019869449.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049821505.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049820163.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_019870261.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis"
XP_049819025.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049817903.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019870422.2	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049823332.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049820644.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_019881975.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_049821257.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_019867271.2	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049826189.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_019872255.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049825826.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_019873820.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_019881270.2	6	MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004	"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"Entner-Doudoroff pathway I"
XP_019871730.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049822683.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-2214320	"Laminin interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Extracellular matrix organization";"Signaling by PDGF";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Anchoring fibril formation"
XP_019874231.2	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_049822453.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation"
XP_049823750.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_019866323.1	8	KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_019866796.1	6	MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497	"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)"
XP_049821854.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049823931.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_019875565.2	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
XP_019873537.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_019867981.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_019881451.1	8	KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-6580;MetaCyc: PWY-4661	"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_019876882.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_019867610.2	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049823334.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_019872238.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_019874296.2	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_019869432.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049820105.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_019870971.2	5	Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_019881977.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019872928.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049820542.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019865559.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049825987.1	9	MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism"
XP_019877701.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_049818489.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049816990.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_019880989.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription"
XP_049824858.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_019867210.2	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049818847.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_049822448.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049819254.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019872426.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_019877758.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_019866250.2	17	MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-4202;MetaCyc: PWY-6620;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-74259;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179	"Guanosine nucleotides degradation III";"Purine salvage";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine catabolism";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine deoxyribonucleosides degradation I"
XP_019865535.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049825438.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049818045.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049824411.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049821925.1	19	Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-418885	"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EGFR downregulation";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling"
XP_049825384.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_049823588.1	5	MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism"
XP_019867211.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049817598.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049819200.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019871180.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019875245.2	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_019867560.2	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049821291.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049820164.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049817605.1	8	Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7210	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_019880271.2	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_019879231.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692	"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity"
XP_019878201.2	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_019871145.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019875792.2	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_019881232.1	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_019867384.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211945	"Endogenous sterols";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Phase I - Functionalization of compounds"
XP_049823164.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049824069.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_019867451.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6722	"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis"
XP_019871747.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049822785.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_019877924.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_019876625.2	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_019874681.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_019864616.2	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049823755.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_019881745.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_019866764.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049818807.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3214841;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"PKMTs methylate histone lysines";"Collagen degradation";"Collagen chain trimerization"
XP_019875936.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_049824803.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019864660.1	7	Reactome: R-HSA-446193;MetaCyc: PWY-5265;Reactome: R-HSA-5633231;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;MetaCyc: PWY-6385	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)"
XP_019880681.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049820158.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_049818438.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019879057.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019868887.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049825125.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019868581.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_019873298.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019869085.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_019871058.2	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_019867057.2	12	KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4	"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Assimilatory sulfate reduction III";"Purine metabolism"
XP_049822641.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_019870012.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_019874189.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_019876336.2	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_019873054.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_019878584.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_019865112.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_019873557.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_019877711.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785	"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome"
XP_049819402.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_019881473.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_019870136.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_019874016.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049817869.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_019880578.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049819959.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049821100.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_019866371.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049819331.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_019877630.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_019864620.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_019868075.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049818529.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_019868389.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049825597.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049818803.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3214841;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"PKMTs methylate histone lysines";"Collagen biosynthesis and modifying enzymes"
XP_019865417.2	7	Reactome: R-HSA-71064;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61	"Lysine catabolism";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_049818594.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation"
XP_019880338.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_019871886.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049818743.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity"
XP_019865457.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_049823523.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049817597.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_019878380.2	10	MetaCyc: PWY-5891;MetaCyc: PWY-5849;MetaCyc: PWY-5890;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-7996;MetaCyc: PWY-5895;Reactome: R-HSA-2142789	"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis"
XP_019878352.2	4	KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_049819232.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_019869663.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049819559.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049826093.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049825391.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049817229.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049819206.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049819907.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex"
XP_049822301.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_019872643.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_019880695.2	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_019865260.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_019878429.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049820255.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_019866333.2	8	MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-6791461;Reactome: R-HSA-71336;Reactome: R-HSA-5659996;KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6;KEGG: 00710+5.3.1.6	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"