Accession_ID Pathway_Count Pathway_IDs Pathway_Names APLA012619-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA004610-PA 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" APLA007932-PA 5 Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" APLA014054-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA004539-PA 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" APLA001069-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" APLA002485-PA 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" APLA009411-PA 7 Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798 "Activation of SMO";"Hedgehog 'on' state";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell" APLA007415-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA001320-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA001833-PA 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" APLA008836-PA 56 Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974 "Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway" APLA011261-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA005238-PA 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" APLA012200-PA 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" APLA014835-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA008491-PA 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" APLA003249-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA012039-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA008532-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" APLA003098-PA 7 MetaCyc: PWY-6840;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2 "Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism" APLA005741-PA 10 MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;Reactome: R-HSA-196757 "Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"L-histidine degradation III";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines" APLA000197-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA000708-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291 "HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C" APLA014921-PA 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway" APLA000210-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA006635-PA 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" APLA005792-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA004068-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" APLA000402-PA 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" APLA003085-PA 13 Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320 "Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Laminin interactions";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Integrin cell surface interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation" APLA005049-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA006685-PA 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" APLA009090-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA001603-PA 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" APLA011572-PA 5 Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148 "Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA010286-PA 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" APLA015399-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA005549-PA 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" APLA006774-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA006992-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA005336-PA 27 Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822 "HCMV Late Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein" APLA003890-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA004081-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" APLA001620-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA000516-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA008022-PA 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" APLA011337-PA 4 Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" APLA000903-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA004341-PA 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA011125-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA008519-PA 5 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins" APLA002395-PA 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" APLA007291-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA009984-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA009924-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA010550-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" APLA001607-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA007372-PA 1 Reactome: R-HSA-419771 "Opsins" APLA007435-PA 6 KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539 "Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism" APLA007689-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA003187-PA 14 Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery" APLA012893-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA004787-PA 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" APLA010382-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" APLA008197-PA 5 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)" APLA003771-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA005271-PA 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" APLA010940-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA007739-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" APLA002181-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA012998-PA 1 Reactome: R-HSA-5635838 "Activation of SMO" APLA005270-PA 6 MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17 "L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism" APLA008535-PA 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" APLA009193-PA 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722 "RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex" APLA004822-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA000689-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA008485-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" APLA008833-PA 7 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" APLA013595-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA001768-PA 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" APLA004277-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA014158-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA010425-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA004630-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA005788-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA003561-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA007353-PA 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" APLA010862-PA 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" APLA007909-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" APLA000468-PA 42 KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00640+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-6945;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-5138;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7401;MetaCyc: PWY-5109;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7216;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177 "Fatty acid degradation";"Fatty acid salvage";"Aminobenzoate degradation";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Propanoate metabolism";"Butanoate metabolism";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Benzoate degradation";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"Spodoptera littoralis pheromone biosynthesis";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"2-methylpropene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"Geraniol degradation";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to butanol II (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Tryptophan metabolism";"Toluene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Glutaryl-coa degradation" APLA008553-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" APLA007667-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" APLA002582-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA007925-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" APLA004579-PA 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" APLA014501-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA004615-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" APLA010695-PA 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" APLA007530-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA013123-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA014155-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA002323-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA013219-PA 6 MetaCyc: PWY-5789;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" APLA005348-PA 7 Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133 "Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1" APLA008807-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" APLA010733-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA011488-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA009925-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA010385-PA 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" APLA002965-PA 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)" APLA014679-PA 14 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-69273 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition" APLA009217-PA 6 Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium" APLA010457-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA006696-PA 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" APLA000028-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA000829-PA 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" APLA003966-PA 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" APLA001661-PA 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" APLA001074-PA 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" APLA000668-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA012291-PA 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" APLA005169-PA 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" APLA005274-PA 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" APLA010400-PA 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" APLA003793-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" APLA004699-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA003842-PA 40 Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167242 "RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat" APLA002237-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA015057-PA 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763;Reactome: R-HSA-3928662 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction";"EPHB-mediated forward signaling" APLA009585-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" APLA005078-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA002988-PA 10 Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation" APLA008497-PA 7 Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination" APLA010653-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA014427-PA 3 KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis" APLA012986-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA008273-PA 4 MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" APLA002364-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" APLA005946-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA011095-PA 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" APLA002294-PA 16 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis" APLA003860-PA 5 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20 "Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes" APLA009772-PA 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" APLA008939-PA 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" APLA013385-PA 9 Reactome: R-HSA-3371599;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1 "Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Pyruvate metabolism" APLA006357-PA 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" APLA008948-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA000105-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA015416-PA 26 Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9609690 "Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Cilium Assembly";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"HCMV Early Events" APLA012983-PA 18 MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642 "Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"(R)-cysteate degradation" APLA000217-PA 6 Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-7077;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25 "Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" APLA014771-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" APLA006990-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA013750-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA014973-PA 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" APLA002790-PA 14 Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110312 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Polymerase switching";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1" APLA012845-PA 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" APLA003228-PA 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" APLA013811-PA 4 MetaCyc: PWY-2781;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" APLA015396-PA 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" APLA010110-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA001872-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" APLA004173-PA 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6 "Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism" APLA000593-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA013122-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA011394-PA 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" APLA004209-PA 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" APLA005749-PA 18 Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839 "Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Synthesis of PA";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PE" APLA010884-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" APLA011746-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA012152-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA014028-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" APLA014283-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA008781-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" APLA004293-PA 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism" APLA000024-PA 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" APLA006361-PA 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" APLA005829-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA001207-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA009660-PA 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" APLA003608-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)" APLA014384-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" APLA007919-PA 14 KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7218 "Methane metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" APLA012600-PA 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" APLA005695-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA011706-PA 57 Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258 "Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL" APLA004257-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA011224-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA002403-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" APLA000151-PA 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" APLA003696-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA010141-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA002533-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA009991-PA 3 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" APLA001288-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" APLA008007-PA 3 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" APLA004196-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA012166-PA 5 Reactome: R-HSA-1234158;Reactome: R-HSA-1234176;Reactome: R-HSA-8849473;Reactome: R-HSA-1234174;Reactome: R-HSA-8951664 "Regulation of gene expression by Hypoxia-inducible Factor";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"PTK6 Expression";"Cellular response to hypoxia";"Neddylation" APLA003471-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA006452-PA 4 Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360 "Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" APLA000426-PA 36 Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-5419276;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5368286;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5389840 "Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Mitochondrial translation termination";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Mitochondrial translation initiation";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitochondrial translation elongation" APLA002126-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA013769-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" APLA002484-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA004808-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA009834-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA004181-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA004276-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA008746-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA003750-PA 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" APLA011491-PA 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" APLA012117-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA004622-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA004858-PA 1 Reactome: R-HSA-400253 "Circadian Clock" APLA008182-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA004705-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA006026-PA 13 Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902 "Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)" APLA001234-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA007345-PA 1 Reactome: R-HSA-211981 "Xenobiotics" APLA004376-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA009762-PA 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" APLA008598-PA 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" APLA005811-PA 12 MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Purine metabolism";"Biotin transport and metabolism" APLA004210-PA 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" APLA010574-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA015161-PA 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" APLA008135-PA 13 MetaCyc: PWY-7857;MetaCyc: PWY-5133;Reactome: R-HSA-71384;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108 "Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Ethanol oxidation";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V" APLA004746-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" APLA015425-PA 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" APLA007416-PA 11 Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787 "PKA activation";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state" APLA004800-PA 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" APLA009052-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" APLA012002-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" APLA005349-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA008533-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" APLA001202-PA 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7187 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" APLA009847-PA 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" APLA005035-PA 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" APLA014528-PA 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" APLA003076-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" APLA013705-PA 10 MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385 "Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)" APLA007523-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA000126-PA 56 Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178 "UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" APLA014822-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA010376-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" APLA002555-PA 19 Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-975634 "Chylomicron assembly";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"VLDL assembly";"Chylomicron remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class B Receptors";"VLDL clearance";"Retinoid metabolism and transport" APLA006773-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA003039-PA 11 Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359 "PKA activation";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation" APLA011917-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA006359-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA011159-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA013082-PA 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" APLA005196-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" APLA008693-PA 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" APLA013359-PA 26 Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic" APLA002426-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA013765-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" APLA000238-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA014459-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA000921-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA009433-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA010573-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA010503-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA002849-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA002548-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" APLA007861-PA 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" APLA002573-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA000258-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" APLA011586-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" APLA013924-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" APLA002544-PA 6 MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" APLA001309-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA009117-PA 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" APLA011765-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA010815-PA 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" APLA007878-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA012027-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA010588-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA000549-PA 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" APLA001933-PA 6 MetaCyc: PWY-7765;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-6309;MetaCyc: PWY-5651 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" APLA005503-PA 6 MetaCyc: PWY-7356;MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-6908 "Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)" APLA003246-PA 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" APLA006961-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA004183-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" APLA002704-PA 4 Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963 "Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I" APLA001292-PA 7 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-264870 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Neutrophil degranulation";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins" APLA003474-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA008595-PA 1 Reactome: R-HSA-196757 "Metabolism of folate and pterines" APLA002343-PA 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" APLA001711-PA 3 MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17 "Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism" APLA002333-PA 11 Reactome: R-HSA-8851680;Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;MetaCyc: PWY-6999;MetaCyc: PWY-6606;MetaCyc: PWY-6538 "Butyrophilin (BTN) family interactions";"Purine catabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Inosine 5'-phosphate degradation";"Theophylline degradation";"Guanosine nucleotides degradation II";"Caffeine degradation III (bacteria, via demethylation)" APLA015308-PA 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" APLA002864-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA008243-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" APLA003382-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA008027-PA 14 KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis" APLA013222-PA 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation" APLA001827-PA 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" APLA013198-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA008956-PA 11 Reactome: R-HSA-2173796;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-72163;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" APLA010731-PA 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" APLA013161-PA 7 Reactome: R-HSA-174403;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255 "Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)" APLA004714-PA 4 Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" APLA002412-PA 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" APLA006562-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA010582-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA000565-PA 12 KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142 "Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" APLA005048-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA011526-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA003527-PA 4 Reactome: R-HSA-1632852;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-1660499 "Macroautophagy";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Synthesis of PIPs at the plasma membrane" APLA002667-PA 10 MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166 "Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA" APLA003026-PA 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" APLA002820-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA013754-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA001897-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA003300-PA 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" APLA005551-PA 6 Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706 "RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling" APLA001717-PA 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" APLA009759-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA012978-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" APLA010422-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" APLA006649-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA005637-PA 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" APLA004354-PA 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" APLA001524-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" APLA003279-PA 29 Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" APLA005113-PA 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation" APLA001949-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA008015-PA 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA000344-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA008950-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" APLA001596-PA 33 Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-69656;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776 "RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin D associated events in G1";"Dual incision in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape" APLA012163-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA011215-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA006275-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA005231-PA 27 Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4085377 "Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins" APLA006619-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA010066-PA 14 MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation" APLA006924-PA 14 Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" APLA010065-PA 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" APLA007822-PA 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" APLA000560-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" APLA014978-PA 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" APLA011310-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA003348-PA 8 Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-5610787 "PKA activation";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state" APLA005667-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" APLA013125-PA 9 KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" APLA007350-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" APLA013813-PA 6 Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6798695 "Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation" APLA012887-PA 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation" APLA007636-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA014434-PA 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" APLA005384-PA 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" APLA010555-PA 9 MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism" APLA011278-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA002479-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" APLA001595-PA 14 MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-6453 "2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Plasmalogen biosynthesis";"Synthesis of PC";"Stigma estolide biosynthesis" APLA007371-PA 8 Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-113501 "Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" APLA006474-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" APLA002360-PA 4 Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203 "Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation" APLA009573-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA014398-PA 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" APLA005832-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" APLA001987-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" APLA003036-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA000509-PA 1 Reactome: R-HSA-400253 "Circadian Clock" APLA012304-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA011986-PA 33 Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-159236 "EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA007022-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA011086-PA 9 Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-4420332 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1" APLA009995-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA004859-PA 1 Reactome: R-HSA-446199 "Synthesis of Dolichyl-phosphate" APLA004044-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA001921-PA 4 Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017 "Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" APLA003242-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA004652-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA012071-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" APLA014869-PA 5 Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68 "Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" APLA008614-PA 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" APLA006128-PA 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" APLA004544-PA 17 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA012660-PA 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" APLA009415-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" APLA010995-PA 56 Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236 "Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"UCH proteinases";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" APLA013913-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA008521-PA 1 Reactome: R-HSA-8949613 "Cristae formation" APLA007949-PA 6 Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" APLA013701-PA 14 Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408 "Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation" APLA009727-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" APLA009092-PA 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" APLA013231-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" APLA009098-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" APLA012125-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" APLA008801-PA 3 Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-8936459 "Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" APLA007910-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" APLA001015-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA000069-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA004082-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" APLA009177-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" APLA001876-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA000414-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA003772-PA 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" APLA014725-PA 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" APLA008744-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA010570-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" APLA000252-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" APLA014059-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA000773-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA009467-PA 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" APLA001456-PA 15 Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167290 "RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation" APLA002455-PA 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" APLA010367-PA 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" APLA003682-PA 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" APLA009005-PA 11 KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206 "Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation" APLA001837-PA 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" APLA002909-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" APLA014046-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" APLA007118-PA 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" APLA004696-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA007463-PA 56 Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-1236974 "Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway" APLA011994-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" APLA010532-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA007375-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" APLA014874-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA003669-PA 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" APLA007576-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" APLA013753-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA014334-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA001389-PA 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" APLA004803-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA007315-PA 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" APLA009379-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA002355-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" APLA008574-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" APLA011369-PA 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" APLA008225-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA003480-PA 22 Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5675221 "Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway" APLA002545-PA 31 MetaCyc: PWY-6519;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-8047;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-7663;MetaCyc: PWY-8049;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-5366;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-7746;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-75105;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;MetaCyc: PWY-7858;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-7664;MetaCyc: PWY-6799 "8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis";"Fatty acyl-CoA biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)" APLA008862-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA015112-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" APLA011060-PA 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" APLA005132-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" APLA001426-PA 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" APLA001601-PA 56 Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" APLA012008-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" APLA001397-PA 8 KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171 "Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis" APLA002194-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA014024-PA 17 Reactome: R-HSA-6796648;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-75955;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16 "TP53 Regulates Transcription of DNA Repair Genes";"Th1 and Th2 cell differentiation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"T cell receptor signaling pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA002074-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" APLA003482-PA 27 Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3371453 "Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response" APLA002675-PA 12 Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-350054 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" APLA002639-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" APLA010675-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" APLA007946-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" APLA010596-PA 26 Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Cilium Assembly";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins" APLA006746-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA008603-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA008095-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" APLA009856-PA 16 Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897 "Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes" APLA000547-PA 18 Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167246 "mRNA Capping";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript" APLA001846-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA013024-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA007820-PA 1 Reactome: R-HSA-1483191 "Synthesis of PC" APLA006974-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" APLA010654-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA004816-PA 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" APLA010839-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA002087-PA 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" APLA013392-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis" APLA010143-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" APLA001387-PA 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" APLA012544-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA008839-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA000271-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" APLA012657-PA 3 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism" APLA004465-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" APLA010448-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA009210-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA004617-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" APLA006252-PA 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" APLA005785-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA003843-PA 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling" APLA014683-PA 10 KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-4661;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855167 "Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol" APLA000332-PA 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" APLA006438-PA 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" APLA012266-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA005063-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" APLA005950-PA 4 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" APLA008846-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA000239-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA011863-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" APLA003507-PA 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" APLA001819-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA008995-PA 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" APLA000757-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" APLA013911-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA002373-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA011364-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" APLA010842-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA006575-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" APLA009927-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA006927-PA 1 Reactome: R-HSA-5617833 "Cilium Assembly" APLA005870-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA009658-PA 7 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" APLA008229-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA009586-PA 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" APLA009226-PA 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" APLA003237-PA 5 Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670 "Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis" APLA003813-PA 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" APLA004632-PA 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" APLA001936-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA008691-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA006697-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA000303-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA005967-PA 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" APLA005612-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" APLA007870-PA 4 Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" APLA012561-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA015383-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA002494-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA011655-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA012593-PA 56 Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-180585 "Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G" APLA002114-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" APLA001003-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" APLA014154-PA 2 Reactome: R-HSA-71384;KEGG: 00030+1.1.1.47 "Ethanol oxidation";"Pentose phosphate pathway" APLA008708-PA 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" APLA002651-PA 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" APLA006050-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" APLA007498-PA 7 Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-165181 "Macroautophagy";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB" APLA006918-PA 9 MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-6983 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis" APLA002270-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" APLA005748-PA 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801 "Ether lipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Synthesis of PA";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS" APLA002731-PA 5 MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667 "Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I" APLA014196-PA 7 MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7 "Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis" APLA011250-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" APLA015481-PA 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" APLA012302-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA003429-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" APLA011318-PA 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" APLA013703-PA 52 Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-167242;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-75955;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-72086 "mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"mRNA Capping" APLA007662-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA008220-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA004796-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA001443-PA 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation" APLA012083-PA 8 KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" APLA003769-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" APLA008745-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA002303-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA009966-PA 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" APLA013928-PA 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" APLA010096-PA 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" APLA011532-PA 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" APLA008766-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA000667-PA 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" APLA008185-PA 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" APLA015314-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" APLA004738-PA 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" APLA012969-PA 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" APLA011825-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" APLA011927-PA 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum" APLA001018-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA003127-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" APLA003222-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA006650-PA 1 Reactome: R-HSA-5676934 "Protein repair" APLA014513-PA 9 Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-69166 "Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Removal of the Flap Intermediate" APLA001009-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA004099-PA 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism" APLA005702-PA 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation" APLA001572-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" APLA000079-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" APLA005525-PA 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" APLA009483-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA008788-PA 5 Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" APLA003586-PA 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" APLA005912-PA 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" APLA000050-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" APLA004877-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" APLA008941-PA 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" APLA004572-PA 4 Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" APLA011772-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" APLA000040-PA 4 Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642 "Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation" APLA009882-PA 8 Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111459 "Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Neutrophil degranulation";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage" APLA003470-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA009436-PA 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" APLA014017-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" APLA007097-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA004372-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" APLA014713-PA 12 Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" APLA012570-PA 7 KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;Reactome: R-HSA-196757;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841 "One carbon pool by folate";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Folate transformations II (plants)" APLA015217-PA 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" APLA005493-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA000110-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" APLA002938-PA 27 Reactome: R-HSA-167200;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6803529;Reactome: R-HSA-77595;Reactome: R-HSA-975957;Reactome: R-HSA-111367;Reactome: R-HSA-159236;Reactome: R-HSA-674695;Reactome: R-HSA-191859;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-77588;Reactome: R-HSA-72203;Reactome: R-HSA-159227;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-975956;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-159230 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"FGFR2 alternative splicing";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Pre-transcription Events";"snRNP Assembly";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Transport of the SLBP Dependant Mature mRNA" APLA011553-PA 2 Reactome: R-HSA-1222556;Reactome: R-HSA-392154 "ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase" APLA005242-PA 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" APLA009304-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" APLA004319-PA 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" APLA001307-PA 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" APLA000490-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA015192-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" APLA007920-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" APLA014581-PA 1 Reactome: R-HSA-419771 "Opsins" APLA014344-PA 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" APLA012829-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" APLA001395-PA 6 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)" APLA005719-PA 56 Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"UCH proteinases";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs" APLA009232-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA011587-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" APLA010672-PA 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" APLA011062-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA012698-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" APLA005954-PA 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" APLA007067-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA005600-PA 1 Reactome: R-HSA-71288 "Creatine metabolism" APLA012988-PA 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" APLA003061-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA002428-PA 57 Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-1236974 "Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway" APLA001414-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA000601-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" APLA006509-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA009419-PA 5 Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis" APLA003042-PA 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" APLA007750-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA007954-PA 4 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)" APLA006547-PA 10 MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1 "Glycerol degradation to butanol";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms" APLA006597-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" APLA008463-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" APLA014868-PA 5 KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate" APLA000537-PA 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" APLA008154-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA001685-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" APLA000953-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA005398-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA002022-PA 3 Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942 "Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)" APLA000499-PA 14 MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-5497;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201 "Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Metabolism of folate and pterines";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I" APLA004415-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA011432-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA005606-PA 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events" APLA002838-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA001945-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" APLA013662-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA005949-PA 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" APLA001416-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA005327-PA 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" APLA006663-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA000328-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA006387-PA 12 MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133 "Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis" APLA001520-PA 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" APLA013280-PA 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" APLA014873-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA009260-PA 3 Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" APLA010787-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA005458-PA 6 MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism" APLA001319-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA003467-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA013393-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA003172-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA006203-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" APLA002840-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA000690-PA 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" APLA004837-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA003677-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" APLA006557-PA 9 Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-8052 "G alpha (q) signalling events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis" APLA005482-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" APLA001626-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA010464-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" APLA009744-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA013156-PA 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" APLA011848-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA001011-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA005550-PA 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" APLA002236-PA 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" APLA004923-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" APLA014432-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" APLA008436-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" APLA000125-PA 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" APLA002024-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" APLA007715-PA 8 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" APLA002737-PA 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" APLA009959-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" APLA008830-PA 8 Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" APLA008596-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA008242-PA 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301 "Inositol phosphate metabolism";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis" APLA006330-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA012981-PA 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" APLA008799-PA 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" APLA001093-PA 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" APLA004095-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" APLA005624-PA 1 Reactome: R-HSA-200425 "Carnitine metabolism" APLA012596-PA 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569 "HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" APLA011248-PA 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006 "Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" APLA012910-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" APLA011947-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA014787-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA006947-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA003598-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA012813-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" APLA005501-PA 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" APLA004501-PA 7 MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes" APLA007805-PA 6 Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA007426-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA008466-PA 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" APLA002345-PA 11 Reactome: R-HSA-500753;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7400;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686;MetaCyc: PWY-7791 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"UMP biosynthesis III" APLA011309-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" APLA014097-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA014646-PA 10 Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" APLA011270-PA 4 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" APLA015453-PA 6 KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723 "Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Rubisco shunt" APLA012875-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA001638-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA000781-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA010752-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA014966-PA 9 MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" APLA008442-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" APLA014831-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA001878-PA 19 Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913 "Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)" APLA011443-PA 1 Reactome: R-HSA-400253 "Circadian Clock" APLA015208-PA 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" APLA005412-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA014197-PA 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" APLA014250-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA005998-PA 7 Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis" APLA014804-PA 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" APLA012568-PA 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" APLA008024-PA 5 KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7902 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis" APLA000730-PA 10 Reactome: R-HSA-6798695;Reactome: R-HSA-975634;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-2453864;MetaCyc: PWY-7849;Reactome: R-HSA-3000171;MetaCyc: PWY-5691;Reactome: R-HSA-977225;Reactome: R-HSA-2453902 "Neutrophil degranulation";"Retinoid metabolism and transport";"Purine metabolism";"Urate conversion to allantoin II";"Retinoid cycle disease events";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)" APLA003093-PA 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" APLA004865-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" APLA000828-PA 6 MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" APLA007531-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" APLA004043-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" APLA012150-PA 11 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Ub-specific processing proteases";"HIV Transcription Initiation" APLA005944-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA012151-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" APLA007963-PA 1 Reactome: R-HSA-189451 "Heme biosynthesis" APLA007691-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA006630-PA 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" APLA012585-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA001686-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" APLA007137-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" APLA014284-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" APLA012085-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" APLA001022-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA007656-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA011266-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA011389-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" APLA004101-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" APLA001095-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA006346-PA 5 Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER" APLA014107-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" APLA002995-PA 17 MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" APLA015344-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA007971-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA009119-PA 4 Reactome: R-HSA-5368286;Reactome: R-HSA-2514853;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Condensation of Prometaphase Chromosomes";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA002191-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA003468-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA004011-PA 7 MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724 "Starch degradation V";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation II" APLA008920-PA 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" APLA014743-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA013848-PA 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" APLA013752-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA007945-PA 12 Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692 "Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"TNF signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR" APLA002653-PA 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" APLA002002-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA001892-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA000428-PA 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" APLA002954-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA001852-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA004373-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA003428-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" APLA002686-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA001904-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" APLA009324-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" APLA003269-PA 16 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" APLA000142-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA013500-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA013203-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA001163-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA012599-PA 13 KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" APLA009120-PA 7 Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201 "Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Mitochondrial protein import";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis" APLA005586-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA010397-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA013081-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA008526-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA010445-PA 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" APLA013902-PA 9 Reactome: R-HSA-69017;Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962 "CDK-mediated phosphorylation and removal of Cdc6";"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex" APLA006233-PA 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" APLA001655-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA014716-PA 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" APLA004793-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA010469-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" APLA010182-PA 8 Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-381676 "PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" APLA007592-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA001699-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA013578-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA009874-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" APLA010783-PA 1 Reactome: R-HSA-419771 "Opsins" APLA010851-PA 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" APLA007959-PA 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" APLA007972-PA 6 Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" APLA001514-PA 26 Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-9617629 "PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation" APLA010151-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" APLA007580-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" APLA009079-PA 18 MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA" APLA009097-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA001145-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA000951-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA000823-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" APLA013499-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA002383-PA 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" APLA008562-PA 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" APLA005893-PA 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" APLA012551-PA 6 Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16 "Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA012699-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA002873-PA 57 Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-75815 "Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D" APLA002096-PA 7 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism" APLA002055-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" APLA012417-PA 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" APLA002172-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA005919-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA000382-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" APLA015065-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" APLA013217-PA 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" APLA001263-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling" APLA005540-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" APLA012145-PA 18 KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00400+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642 "Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Arginine biosynthesis";"(R)-cysteate degradation" APLA012976-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA015205-PA 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" APLA002543-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA011992-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA002058-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" APLA009709-PA 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" APLA011328-PA 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" APLA009426-PA 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" APLA003884-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA008827-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" APLA003989-PA 1 Reactome: R-HSA-8949613 "Cristae formation" APLA002486-PA 4 Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753 "Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions" APLA011260-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" APLA003536-PA 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events" APLA002968-PA 5 MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106 "Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis" APLA000031-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA009144-PA 3 Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361 "Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins" APLA015082-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA011294-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001635-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" APLA008681-PA 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" APLA001014-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA010637-PA 6 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" APLA011304-PA 1 Reactome: R-HSA-8949613 "Cristae formation" APLA011531-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA011480-PA 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" APLA006174-PA 40 MetaCyc: PWY-6946;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-6945;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-7778;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-7656;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-7401;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361 "Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid elongation";"Fatty acid salvage";"Aminobenzoate degradation";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Benzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Caprolactam degradation";"Lysine degradation";"Limonene and pinene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"Toluene degradation";"Pyruvate fermentation to butanol II (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)" APLA004969-PA 6 KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" APLA008917-PA 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" APLA004130-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA011797-PA 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" APLA009731-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" APLA001985-PA 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" APLA003210-PA 11 Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic" APLA001132-PA 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" APLA000081-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA007670-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" APLA010883-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA000320-PA 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" APLA003633-PA 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" APLA005772-PA 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" APLA000592-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" APLA006079-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" APLA003091-PA 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" APLA014289-PA 13 MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384 "Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)" APLA014377-PA 6 Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation" APLA012076-PA 5 KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6 "Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism" APLA013212-PA 10 MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;Reactome: R-HSA-162699;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4717374 "Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate mannose";"N-Glycan biosynthesis";"Defective DPM1 causes DPM1-CDG (CDG-1e)" APLA015456-PA 17 MetaCyc: PWY-6728;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37 "Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" APLA013073-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA000900-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA004306-PA 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism" APLA000454-PA 10 Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828 "Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Negative regulation of MET activity";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Clathrin-mediated endocytosis" APLA014850-PA 26 Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"HCMV Early Events";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins" APLA010644-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA015204-PA 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" APLA013070-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA005704-PA 52 Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-8939236 "CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" APLA000510-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" APLA013060-PA 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" APLA011913-PA 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" APLA003882-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA004656-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA009518-PA 5 Reactome: R-HSA-159236;Reactome: R-HSA-73856;KEGG: 00480+3.4.11.1;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Glutathione metabolism";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" APLA006973-PA 3 KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980 "Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis" APLA011781-PA 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" APLA000590-PA 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism" APLA008949-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" APLA011921-PA 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" APLA000807-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway" APLA001937-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA003710-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" APLA001451-PA 13 KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948 "Relaxin signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants" APLA002859-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" APLA003040-PA 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" APLA013079-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA011701-PA 4 Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" APLA004524-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" APLA010274-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" APLA000324-PA 1 Reactome: R-HSA-71288 "Creatine metabolism" APLA008561-PA 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" APLA011005-PA 16 Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176408 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase" APLA009224-PA 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" APLA001478-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" APLA013466-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA012616-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA006185-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA009642-PA 10 Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111464 "Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" APLA008116-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA000130-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" APLA014601-PA 8 Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6804756 "Lipophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation" APLA011326-PA 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" APLA001653-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA008023-PA 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" APLA013076-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA012199-PA 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" APLA006684-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA013770-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA000316-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA002644-PA 1 Reactome: R-HSA-71064 "Lysine catabolism" APLA008930-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA009375-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA010011-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA001690-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA010641-PA 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" APLA004698-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA004532-PA 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" APLA002042-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA006681-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA013309-PA 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" APLA013710-PA 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" APLA011092-PA 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" APLA015017-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" APLA012012-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA003519-PA 7 Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-6596 "Neutrophil degranulation";"Purine metabolism";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I" APLA013284-PA 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" APLA006305-PA 11 Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986 "ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2" APLA002352-PA 3 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" APLA007911-PA 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" APLA010998-PA 5 MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" APLA009923-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA011305-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA005470-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA001600-PA 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" APLA011722-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" APLA010018-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" APLA012410-PA 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis" APLA013678-PA 3 MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" APLA008103-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" APLA014913-PA 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" APLA009443-PA 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" APLA000032-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" APLA000317-PA 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" APLA012033-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA011973-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" APLA009873-PA 4 Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" APLA015322-PA 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" APLA013950-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA000398-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA010056-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" APLA010033-PA 7 KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism" APLA003229-PA 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" APLA008555-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" APLA014142-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" APLA008768-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" APLA003197-PA 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" APLA005959-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA012406-PA 13 Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation" APLA012321-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA010419-PA 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" APLA004543-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA000777-PA 5 Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-5668599 "PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases" APLA009758-PA 8 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription" APLA001313-PA 56 Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1" APLA005498-PA 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" APLA007612-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA000788-PA 6 MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)" APLA007545-PA 1 Reactome: R-HSA-211981 "Xenobiotics" APLA004752-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA001973-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA003914-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA001407-PA 6 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" APLA002640-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA001952-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA015433-PA 14 MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" APLA010600-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA014006-PA 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" APLA010313-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" APLA005378-PA 18 KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;Reactome: R-HSA-70263;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-7115;MetaCyc: PWY-6728 "Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle" APLA012856-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" APLA001574-PA 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" APLA002381-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA005337-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA009728-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" APLA005272-PA 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" APLA008984-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" APLA012306-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA001410-PA 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" APLA007705-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA008080-PA 13 Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;Reactome: R-HSA-416572;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "EPHA-mediated growth cone collapse";"Thermogenesis";"mTOR signaling pathway";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"Sema4D induced cell migration and growth-cone collapse";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" APLA003169-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA008643-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" APLA008300-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" APLA000606-PA 5 Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" APLA003096-PA 7 MetaCyc: PWY-6840;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255 "Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)" APLA014253-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA004184-PA 6 Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" APLA012208-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA010716-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA006976-PA 3 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2 "ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation" APLA008224-PA 1 Reactome: R-HSA-2028269 "Signaling by Hippo" APLA003714-PA 3 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis" APLA012840-PA 10 Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756 "Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation" APLA005648-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA002451-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" APLA004965-PA 4 Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228 "Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix" APLA012605-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA012536-PA 9 MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476 "2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"G alpha (q) signalling events" APLA003037-PA 11 Reactome: R-HSA-163615;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787 "PKA activation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state" APLA011346-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA001070-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" APLA010127-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA008083-PA 3 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA001914-PA 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" APLA013281-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA012594-PA 7 Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" APLA000830-PA 7 Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939 "DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" APLA006461-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" APLA001860-PA 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" APLA008770-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA010776-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA011093-PA 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" APLA007811-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA003217-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" APLA013711-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA014069-PA 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" APLA012869-PA 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" APLA011613-PA 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761 "Neddylation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling" APLA008504-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA013338-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA000810-PA 56 Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751 "Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity" APLA000366-PA 8 Reactome: R-HSA-73614;MetaCyc: PWY-6556;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage" APLA004314-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA008066-PA 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" APLA000266-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" APLA006367-PA 3 Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" APLA012118-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA004625-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA015371-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA005195-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" APLA003226-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA010347-PA 56 Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764 "Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling" APLA008838-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA006563-PA 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" APLA014103-PA 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" APLA000397-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" APLA012413-PA 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" APLA009677-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA008014-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA006664-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" APLA012909-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA004868-PA 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" APLA013331-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA013952-PA 11 Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096 "Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG degradation" APLA005283-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA008850-PA 9 MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;Reactome: R-HSA-1475029 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide" APLA008538-PA 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" APLA005545-PA 20 KEGG: 04926+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"mTOR signalling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Thermogenesis" APLA004032-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA000357-PA 14 MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-7279 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)" APLA011268-PA 1 MetaCyc: PWY-6938 "NADH repair" APLA002520-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA007558-PA 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" APLA002390-PA 8 Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" APLA004070-PA 1 Reactome: R-HSA-525793 "Myogenesis" APLA003381-PA 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" APLA009000-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" APLA011983-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" APLA004094-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA012467-PA 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" APLA003266-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA014441-PA 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" APLA014007-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" APLA007481-PA 1 Reactome: R-HSA-71064 "Lysine catabolism" APLA006453-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA011104-PA 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" APLA006221-PA 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" APLA001323-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" APLA006988-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA001388-PA 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA" APLA000552-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" APLA004527-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA014769-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" APLA001446-PA 3 KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217 "Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage" APLA001647-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" APLA009515-PA 7 MetaCyc: PWY-6470;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" APLA014391-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" APLA008108-PA 32 Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6803529 "RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing" APLA002332-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" APLA012186-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA003087-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" APLA008686-PA 57 Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590 "CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling" APLA004280-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" APLA001077-PA 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" APLA010136-PA 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" APLA014519-PA 6 Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium" APLA000839-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA003891-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA014998-PA 26 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin" APLA001625-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA010276-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA000539-PA 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" APLA003168-PA 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" APLA012089-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA000950-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA005614-PA 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway" APLA001863-PA 1 Reactome: R-HSA-9640463 "Wax biosynthesis" APLA002423-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" APLA004191-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" APLA013883-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA003046-PA 52 Reactome: R-HSA-72165;Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-167242;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73980;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-167161 "mRNA Splicing - Minor Pathway";"RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation" APLA007722-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA005862-PA 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" APLA008742-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA009207-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA007823-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA001549-PA 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" APLA004905-PA 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" APLA014272-PA 182 Reactome: R-HSA-5675221;Reactome: R-HSA-8876493;Reactome: R-HSA-72649;Reactome: R-HSA-174084;Reactome: R-HSA-5689877;Reactome: R-HSA-2173791;Reactome: R-HSA-5689880;Reactome: R-HSA-937039;Reactome: R-HSA-1236382;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5696395;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-2559585;Reactome: R-HSA-110320;Reactome: R-HSA-174184;Reactome: R-HSA-3134975;Reactome: R-HSA-5689896;Reactome: R-HSA-975957;Reactome: R-HSA-69541;Reactome: R-HSA-1236974;Reactome: R-HSA-72706;Reactome: R-HSA-5654732;Reactome: R-HSA-2565942;Reactome: R-HSA-450408;Reactome: R-HSA-532668;Reactome: R-HSA-5610785;Reactome: R-HSA-2173795;Reactome: R-HSA-5654727;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-6781823;Reactome: R-HSA-5656121;Reactome: R-HSA-168928;Reactome: R-HSA-6782135;Reactome: R-HSA-182971;Reactome: R-HSA-2691232;Reactome: R-HSA-5675482;Reactome: R-HSA-937041;Reactome: R-HSA-2122948;Reactome: R-HSA-2408557;Reactome: R-HSA-9637628;Reactome: R-HSA-2672351;Reactome: R-HSA-168927;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-5656169;Reactome: R-HSA-68827;Reactome: R-HSA-9613829;Reactome: R-HSA-2871837;Reactome: R-HSA-6807004;Reactome: R-HSA-9013507;Reactome: R-HSA-4641263;Reactome: R-HSA-175474;Reactome: R-HSA-2559580;Reactome: R-HSA-8852276;Reactome: R-HSA-205043;Reactome: R-HSA-5693607;Reactome: R-HSA-1169408;Reactome: R-HSA-912631;Reactome: R-HSA-72702;Reactome: R-HSA-8939236;Reactome: R-HSA-72695;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-5632684;Reactome: R-HSA-162588;Reactome: R-HSA-9636383;Reactome: R-HSA-5696394;Reactome: R-HSA-4608870;Reactome: R-HSA-1253288;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-8948751;Reactome: R-HSA-192823;Reactome: R-HSA-1358803;Reactome: R-HSA-5684264;Reactome: R-HSA-1295596;Reactome: R-HSA-9013973;Reactome: R-HSA-8863795;Reactome: R-HSA-202424;Reactome: R-HSA-3785653;Reactome: R-HSA-975956;Reactome: R-HSA-174113;Reactome: R-HSA-5693565;Reactome: R-HSA-3769402;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-8866654;Reactome: R-HSA-8854050;Reactome: R-HSA-156827;Reactome: R-HSA-5610783;Reactome: R-HSA-5357905;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-6783310;Reactome: R-HSA-180585;Reactome: R-HSA-975110;Reactome: R-HSA-6782210;Reactome: R-HSA-2173788;Reactome: R-HSA-8866652;Reactome: R-HSA-450302;Reactome: R-HSA-8875360;Reactome: R-HSA-2559582;Reactome: R-HSA-9014325;Reactome: R-HSA-6791226;Reactome: R-HSA-6781827;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-5696397;Reactome: R-HSA-174048;Reactome: R-HSA-5655862;Reactome: R-HSA-69017;Reactome: R-HSA-5685942;Reactome: R-HSA-1799339;Reactome: R-HSA-5205685;Reactome: R-HSA-2979096;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8951664;Reactome: R-HSA-72689;Reactome: R-HSA-5654726;Reactome: R-HSA-211733;Reactome: R-HSA-9633012;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-174154;Reactome: R-HSA-110312;Reactome: R-HSA-2173796;Reactome: R-HSA-187577;Reactome: R-HSA-5654733;Reactome: R-HSA-5689901;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-917937;Reactome: R-HSA-69601;Reactome: R-HSA-2894862;Reactome: R-HSA-6804760;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-6804757;Reactome: R-HSA-72764;Reactome: R-HSA-110314;Reactome: R-HSA-9033241;Reactome: R-HSA-1169091;Reactome: R-HSA-9615710;Reactome: R-HSA-2644606;Reactome: R-HSA-209543;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-209560;Reactome: R-HSA-195253;Reactome: R-HSA-977225;Reactome: R-HSA-174490;Reactome: R-HSA-1234176;Reactome: R-HSA-937042;Reactome: R-HSA-936440;Reactome: R-HSA-9010553;Reactome: R-HSA-975144;Reactome: R-HSA-3322077;Reactome: R-HSA-5678895;Reactome: R-HSA-901032;Reactome: R-HSA-201681;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-445989;Reactome: R-HSA-8856825;Reactome: R-HSA-936964;Reactome: R-HSA-2122947;Reactome: R-HSA-8849469;Reactome: R-HSA-8948747;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-917729;Reactome: R-HSA-5676590;Reactome: R-HSA-156902;Reactome: R-HSA-5696400;Reactome: R-HSA-5610780;Reactome: R-HSA-6804756 "Negative regulation of MAPK pathway";"InlA-mediated entry of Listeria monocytogenes into host cells";"Translation initiation complex formation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Josephin domain DUBs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Ub-specific processing proteases";"IRAK1 recruits IKK complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Formation of Incision Complex in GG-NER";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"Oncogene Induced Senescence";"Translesion Synthesis by POLH";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of innate immune responses to cytosolic DNA";"Ovarian tumor domain proteases";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Stabilization of p53";"ER-Phagosome pathway";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Negative regulation of FGFR3 signaling";"Regulation of PLK1 Activity at G2/M Transition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"GLI3 is processed to GLI3R by the proteasome";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Negative regulation of FGFR2 signaling";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Formation of TC-NER Pre-Incision Complex";"Translesion synthesis by POLI";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Dual incision in TC-NER";"EGFR downregulation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of necroptotic cell death";"IKK complex recruitment mediated by RIP1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Selenocysteine synthesis";"Modulation by Mtb of host immune system";"Stimuli-sensing channels";"TICAM1, RIP1-mediated IKK complex recruitment";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Termination of translesion DNA synthesis";"CDT1 association with the CDC6:ORC:origin complex";"Chaperone Mediated Autophagy";"FCERI mediated NF-kB activation";"Negative regulation of MET activity";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of FZD by ubiquitination";"Assembly Of The HIV Virion";"Oxidative Stress Induced Senescence";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NRIF signals cell death from the nucleus";"Processing of DNA double-strand break ends";"ISG15 antiviral mechanism";"Regulation of signaling by CBL";"Ribosomal scanning and start codon recognition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the ternary complex, and subsequently, the 43S complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"Hedgehog 'on' state";"Budding and maturation of HIV virion";"Prevention of phagosomal-lysosomal fusion";"DNA Damage Recognition in GG-NER";"Asymmetric localization of PCP proteins";"Downregulation of ERBB4 signaling";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"Regulation of PTEN stability and activity";"Viral mRNA Translation";"Downregulation of ERBB2:ERBB3 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Spry regulation of FGF signaling";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2 signaling";"Downstream TCR signaling";"Myoclonic epilepsy of Lafora";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SCF-beta-TrCP mediated degradation of Emi1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deactivation of the beta-catenin transactivating complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"E3 ubiquitin ligases ubiquitinate target proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of GLI2 by the proteasome";"Regulation of TNFR1 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Fanconi Anemia Pathway";"Vif-mediated degradation of APOBEC3G";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Downregulation of TGF-beta receptor signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"activated TAK1 mediates p38 MAPK activation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Senescence-Associated Secretory Phenotype (SASP)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion synthesis by POLK";"CDK-mediated phosphorylation and removal of Cdc6";"HDR through Homologous Recombination (HRR)";"SRP-dependent cotranslational protein targeting to membrane";"Pink/Parkin Mediated Mitophagy";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Separation of Sister Chromatids";"Aggrephagy";"Neddylation";"Formation of a pool of free 40S subunits";"Negative regulation of FGFR1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"APC/C:Cdc20 mediated degradation of Securin";"Translesion synthesis by REV1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of FGFR4 signaling";"Metalloprotease DUBs";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Iron uptake and transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of TP53 Activity through Methylation";"UCH proteinases";"Degradation of AXIN";"Regulation of TP53 Degradation";"Eukaryotic Translation Termination";"Recognition of DNA damage by PCNA-containing replication complex";"Peroxisomal protein import";"Activation of NF-kappaB in B cells";"Late endosomal microautophagy";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"p75NTR recruits signalling complexes";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"NF-kB is activated and signals survival";"Degradation of beta-catenin by the destruction complex";"Amyloid fiber formation";"Membrane binding and targetting of GAG proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"IRAK2 mediated activation of TAK1 complex";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of expression of SLITs and ROBOs";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Glycogen synthesis";"Defective CFTR causes cystic fibrosis";"ER Quality Control Compartment (ERQC)";"TCF dependent signaling in response to WNT";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Cargo recognition for clathrin-mediated endocytosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"NOTCH1 Intracellular Domain Regulates Transcription";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of PTEN localization";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Endosomal Sorting Complex Required For Transport (ESCRT)";"NIK-->noncanonical NF-kB signaling";"Peptide chain elongation";"Dual Incision in GG-NER";"Degradation of GLI1 by the proteasome";"Regulation of TP53 Activity through Phosphorylation" APLA002308-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA002046-PA 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" APLA004447-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA009473-PA 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" APLA000551-PA 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" APLA012675-PA 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" APLA002854-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA011024-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA008234-PA 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" APLA014516-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA011356-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" APLA009050-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA007888-PA 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" APLA000849-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA005502-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" APLA001755-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA008650-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA013714-PA 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" APLA002052-PA 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" APLA000270-PA 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" APLA003259-PA 9 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade" APLA009371-PA 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" APLA003024-PA 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" APLA009489-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA001351-PA 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" APLA012442-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA004098-PA 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" APLA011527-PA 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" APLA007948-PA 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" APLA005297-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA010971-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA012207-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA008741-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA004454-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" APLA008272-PA 6 MetaCyc: PWY-6118;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Synthesis of PA" APLA005703-PA 12 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation" APLA012836-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" APLA003720-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA006643-PA 15 Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" APLA008029-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA012404-PA 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" APLA001229-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA004346-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA014336-PA 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" APLA014477-PA 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" APLA007635-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA000850-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA003033-PA 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" APLA011047-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA010993-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA008337-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA004875-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA011482-PA 9 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" APLA003893-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA007500-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA007139-PA 4 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" APLA005953-PA 14 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" APLA014098-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA011409-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA000545-PA 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" APLA001742-PA 1 Reactome: R-HSA-1296061 "HCN channels" APLA013473-PA 4 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453 "Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response" APLA002019-PA 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" APLA003782-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" APLA000862-PA 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)" APLA012569-PA 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" APLA005818-PA 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" APLA007882-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA008915-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA000158-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA012066-PA 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" APLA003315-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA009992-PA 4 Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656 "Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling" APLA003179-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA012070-PA 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" APLA001067-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" APLA011952-PA 4 Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829 "Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Aggrephagy";"Chaperone Mediated Autophagy" APLA002277-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA003839-PA 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA003313-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" APLA000209-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" APLA006614-PA 7 KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208 "Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism" APLA006458-PA 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis" APLA014343-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" APLA012607-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" APLA008829-PA 3 Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation" APLA012477-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA012149-PA 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" APLA002213-PA 7 MetaCyc: PWY-6470;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis" APLA000150-PA 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" APLA004609-PA 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" APLA009154-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" APLA014002-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" APLA001687-PA 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" APLA006729-PA 1 Reactome: R-HSA-74217 "Purine salvage" APLA010841-PA 3 KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691 "Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I" APLA014655-PA 8 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" APLA001197-PA 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" APLA003964-PA 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" APLA014536-PA 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport" APLA007673-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA007873-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA010777-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA012153-PA 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" APLA009182-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA001435-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA015233-PA 6 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" APLA004217-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" APLA015343-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" APLA003316-PA 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" APLA007956-PA 17 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" APLA004522-PA 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" APLA003107-PA 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" APLA003043-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" APLA011027-PA 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" APLA007492-PA 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA007456-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" APLA010068-PA 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" APLA000863-PA 14 MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)" APLA009089-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" APLA003759-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" APLA012876-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA004449-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA007975-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA011782-PA 1 Reactome: R-HSA-1483191 "Synthesis of PC" APLA012068-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA004175-PA 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6 "Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism" APLA014245-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA011579-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" APLA003440-PA 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" APLA011349-PA 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" APLA003647-PA 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" APLA014433-PA 8 Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616 "E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication" APLA013187-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA009060-PA 1 Reactome: R-HSA-8876725 "Protein methylation" APLA001592-PA 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" APLA010196-PA 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation" APLA012643-PA 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" APLA009180-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" APLA007977-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA006570-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" APLA013400-PA 11 Reactome: R-HSA-163615;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787 "PKA activation";"G alpha (i) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state" APLA005056-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA005819-PA 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA014307-PA 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" APLA005083-PA 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" APLA003634-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA013801-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" APLA010384-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" APLA012011-PA 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" APLA008790-PA 13 Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-5362768;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-8876725 "Neutrophil degranulation";"HSF1 activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"Josephin domain DUBs";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Protein methylation" APLA011713-PA 56 Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902 "CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity" APLA001683-PA 7 Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" APLA012384-PA 12 KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783 "Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation" APLA008767-PA 5 Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-190873 "Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Gap junction degradation" APLA008114-PA 22 Reactome: R-HSA-75876;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-7726;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7053 "Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)" APLA010128-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA000669-PA 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" APLA015304-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA014672-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" APLA001704-PA 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" APLA000938-PA 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" APLA014395-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA010682-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA006584-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" APLA009590-PA 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-912446 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination" APLA011351-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA011135-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" APLA002200-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" APLA008179-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA008961-PA 7 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation" APLA013379-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA002934-PA 10 Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition" APLA012905-PA 3 KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" APLA003655-PA 6 Reactome: R-HSA-3878781;MetaCyc: PWY-7900;Reactome: R-HSA-3322077;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067 "Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" APLA007255-PA 8 Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" APLA001611-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA012226-PA 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" APLA010406-PA 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" APLA015202-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA014022-PA 3 MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450 "Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion" APLA009540-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" APLA010040-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" APLA004353-PA 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" APLA005325-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA002687-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA005145-PA 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" APLA008510-PA 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" APLA015180-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA000483-PA 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" APLA012587-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA009499-PA 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" APLA002318-PA 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" APLA014681-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" APLA010460-PA 57 Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-6798695 "Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Degradation of AXIN";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation" APLA001106-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA005932-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" APLA011359-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" APLA009701-PA 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" APLA003943-PA 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" APLA013236-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA015240-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" APLA009372-PA 18 MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7221 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis" APLA000090-PA 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" APLA000806-PA 16 Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-174048 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B" APLA014759-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" APLA001137-PA 11 MetaCyc: PWY-6549;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42 "L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Glutathione metabolism" APLA014848-PA 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6 "Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" APLA015237-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" APLA004211-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA007201-PA 12 KEGG: 00280+6.4.1.3;MetaCyc: PWY-5743;MetaCyc: PWY-6728;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.3;MetaCyc: PWY-5789;MetaCyc: PWY-7384;Reactome: R-HSA-196780;Reactome: R-HSA-71032;KEGG: 00720+6.4.1.3;KEGG: 00630+6.4.1.3;MetaCyc: PWYG-321 "Valine, leucine and isoleucine degradation";"3-hydroxypropanoate cycle";"Methylaspartate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Biotin transport and metabolism";"Propionyl-CoA catabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"" APLA006695-PA 5 Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" APLA005825-PA 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" APLA009143-PA 8 KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5740;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-7573;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47 "Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism" APLA006698-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA002539-PA 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" APLA001010-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA004281-PA 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" APLA009753-PA 16 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" APLA012185-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" APLA000131-PA 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA006748-PA 5 Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" APLA000613-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA004358-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA013772-PA 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events" APLA009999-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA001399-PA 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" APLA003009-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA009136-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" APLA005715-PA 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" APLA011623-PA 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783 "Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome" APLA011220-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA009661-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA001404-PA 5 Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" APLA008611-PA 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" APLA014048-PA 24 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"HCMV Early Events";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin" APLA013455-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" APLA010595-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA007891-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA006636-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Mitochondrial protein import";"Respiratory electron transport" APLA006060-PA 27 Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-9610379 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events" APLA012141-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" APLA003221-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA014593-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" APLA003252-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" APLA004294-PA 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism" APLA000469-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" APLA012713-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA004772-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA012854-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" APLA002044-PA 13 MetaCyc: PWY-6902;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916 "Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation" APLA009973-PA 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA006991-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA000368-PA 8 Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-917977 "Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling" APLA015335-PA 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" APLA005955-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" APLA005342-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" APLA003426-PA 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" APLA000619-PA 12 KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13 "Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" APLA010491-PA 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" APLA005079-PA 1 Reactome: R-HSA-71336 "Pentose phosphate pathway" APLA002059-PA 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" APLA008112-PA 32 Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-9018519 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression" APLA001658-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" APLA005454-PA 18 Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis" APLA007872-PA 16 Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176408 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase" APLA013062-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" APLA009501-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" APLA005476-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" APLA000554-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA006201-PA 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" APLA014258-PA 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases" APLA009159-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" APLA001648-PA 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" APLA009072-PA 5 MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Formation of apoptosome" APLA014380-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA001953-PA 26 Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-389977 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Aggrephagy";"Post-chaperonin tubulin folding pathway" APLA002142-PA 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" APLA009733-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" APLA007912-PA 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" APLA000737-PA 8 Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27 "Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Propanoate metabolism" APLA013884-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA000512-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA000132-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA005738-PA 4 KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" APLA008934-PA 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" APLA006251-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA004856-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA001650-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA003311-PA 6 Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" APLA010331-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA014278-PA 11 Reactome: R-HSA-163615;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787 "PKA activation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state" APLA003657-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" APLA001210-PA 4 MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" APLA009770-PA 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" APLA008649-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA001129-PA 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" APLA012900-PA 3 KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" APLA015072-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA001000-PA 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation" APLA009816-PA 10 MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667 "Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I" APLA000135-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA002948-PA 5 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-1362409 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" APLA001946-PA 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" APLA003180-PA 10 Reactome: R-HSA-1855204;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-6365 "Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis" APLA001208-PA 5 Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine" APLA000315-PA 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" APLA007102-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA002668-PA 4 Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" APLA009808-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA008808-PA 8 Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" APLA005858-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" APLA000114-PA 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" APLA001547-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA001112-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA002483-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" APLA012901-PA 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" APLA010500-PA 14 MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7218 "Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Methane metabolism";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" APLA010063-PA 14 MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" APLA005338-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" APLA014639-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" APLA001565-PA 1 Reactome: R-HSA-3295583 "TRP channels" APLA006644-PA 5 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" APLA000109-PA 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" APLA009985-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA007931-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA003849-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA005060-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" APLA000345-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA008946-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" APLA015178-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA013075-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA000682-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA001403-PA 5 Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2 "Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" APLA014621-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" APLA007063-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA003023-PA 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" APLA009827-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA002009-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" APLA005076-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" APLA008743-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA003922-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" APLA008275-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA013006-PA 4 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" APLA002710-PA 14 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" APLA001349-PA 4 MetaCyc: PWY-7807;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" APLA014612-PA 3 MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" APLA004154-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA012604-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" APLA014686-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" APLA005665-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" APLA013945-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA010062-PA 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080 "Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I" APLA008339-PA 3 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes" APLA000541-PA 1 Reactome: R-HSA-9640463 "Wax biosynthesis" APLA011730-PA 1 Reactome: R-HSA-418990 "Adherens junctions interactions" APLA006839-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" APLA003018-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" APLA009424-PA 10 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" APLA013191-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" APLA010586-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA005537-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA003886-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA008006-PA 4 MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" APLA004469-PA 18 MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA" APLA006851-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA000543-PA 14 MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" APLA009445-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" APLA013374-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA006625-PA 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" APLA005789-PA 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" APLA015393-PA 1 Reactome: R-HSA-9640463 "Wax biosynthesis" APLA009043-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA003528-PA 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" APLA014775-PA 6 Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" APLA012056-PA 1 Reactome: R-HSA-8964038 "LDL clearance" APLA004639-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" APLA007134-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA008714-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" APLA010643-PA 33 Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-170822 "tRNA processing in the nucleus";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein" APLA014747-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA008236-PA 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" APLA000614-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA007195-PA 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" APLA003946-PA 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" APLA013196-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" APLA007127-PA 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" APLA010312-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" APLA001304-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA006327-PA 14 MetaCyc: PWY-5104;MetaCyc: PWY-7767;MetaCyc: PWY-5103;MetaCyc: PWY-5101;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5057;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5108;MetaCyc: PWY-5078 "L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"L-valine degradation II";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis";"L-leucine degradation III";"L-isoleucine biosynthesis V";"L-isoleucine degradation II" APLA014714-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA002219-PA 7 Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" APLA000673-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" APLA001662-PA 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" APLA011066-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA001459-PA 20 Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210 "Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER" APLA011133-PA 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" APLA008267-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" APLA006256-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA011592-PA 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" APLA000598-PA 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" APLA012450-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA001038-PA 5 Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA014744-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA006952-PA 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" APLA009103-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" APLA012889-PA 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" APLA004089-PA 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling" APLA001540-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA003557-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA002528-PA 10 KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153 "mTOR signaling pathway";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" APLA001839-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA015025-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA009114-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" APLA012135-PA 5 Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" APLA000068-PA 1 Reactome: R-HSA-373753 "Nephrin family interactions" APLA014330-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA014099-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA012421-PA 16 Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-8853659 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"Interleukin-7 signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"RET signaling" APLA000034-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA001856-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001168-PA 4 Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" APLA008509-PA 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" APLA001198-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA006900-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA013078-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA002079-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" APLA009362-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" APLA000359-PA 18 MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis" APLA001836-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" APLA011837-PA 26 Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-9617629;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-210744 "NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"HATs acetylate histones";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" APLA000249-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" APLA002826-PA 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" APLA012874-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA008703-PA 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" APLA001380-PA 10 Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2644606 "Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" APLA012489-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" APLA009482-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA008529-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" APLA012309-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" APLA014194-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA006782-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA009541-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" APLA012574-PA 13 MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism" APLA011984-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" APLA010656-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA004909-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA013210-PA 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" APLA014795-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" APLA010280-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA011864-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" APLA002184-PA 1 Reactome: R-HSA-71288 "Creatine metabolism" APLA002092-PA 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" APLA012408-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA000603-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA013661-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA004494-PA 56 Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"UCH proteinases" APLA004852-PA 1 Reactome: R-HSA-8949613 "Cristae formation" APLA000879-PA 29 Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-674695 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events" APLA014161-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA006721-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA005900-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" APLA004526-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA001916-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA002216-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" APLA001537-PA 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" APLA000955-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" APLA000162-PA 8 Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638 "Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins" APLA001160-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA007660-PA 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" APLA014546-PA 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation" APLA003055-PA 16 Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2467813 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids" APLA007117-PA 1 Reactome: R-HSA-114608 "Platelet degranulation" APLA004512-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA010311-PA 8 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556 "Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Photosynthesis";"ROS and RNS production in phagocytes" APLA011361-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA009503-PA 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" APLA009928-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA012977-PA 56 Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs" APLA004626-PA 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" APLA000913-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA002825-PA 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" APLA009150-PA 5 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs" APLA010150-PA 8 Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" APLA010197-PA 24 Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736 "COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Aggrephagy";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Kinesins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors" APLA011020-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA008274-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" APLA010717-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA008998-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" APLA010647-PA 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" APLA000396-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" APLA010275-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA000638-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA011087-PA 9 Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783 "Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type" APLA005795-PA 10 KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Sphingolipid metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" APLA010499-PA 14 KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7218 "Methane metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" APLA006099-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" APLA007552-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" APLA014127-PA 4 KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion" APLA009901-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" APLA009234-PA 19 Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-8876725;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Protein methylation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" APLA013214-PA 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex" APLA003844-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA010822-PA 6 MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-4381 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)" APLA000674-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" APLA011728-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" APLA005319-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA002148-PA 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism" APLA006379-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination" APLA001518-PA 6 MetaCyc: PWY-6527;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317 "Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" APLA013660-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" APLA007680-PA 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" APLA003171-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA008944-PA 3 MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis" APLA006852-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA005581-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA015197-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" APLA008660-PA 7 Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-165054 "tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA" APLA008403-PA 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" APLA009213-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" APLA012319-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA011447-PA 27 Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107 "HCMV Late Events";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" APLA001817-PA 12 KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23 "Other glycan degradation";"Neutrophil degranulation";"HS-GAG degradation";"Sphingolipid metabolism";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Galactose metabolism" APLA000400-PA 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" APLA007551-PA 5 MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)" APLA010778-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001559-PA 1 Reactome: R-HSA-373752 "Netrin-1 signaling" APLA006738-PA 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" APLA009657-PA 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" APLA000639-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" APLA006962-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA011246-PA 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling" APLA003025-PA 1 Reactome: R-HSA-400253 "Circadian Clock" APLA015230-PA 3 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2 "Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis" APLA000225-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA014534-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" APLA000262-PA 17 MetaCyc: PWY-6611;MetaCyc: PWY-6627;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1 "Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine catabolism";"Pyrimidine metabolism" APLA008155-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA014423-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA001668-PA 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" APLA011836-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA003089-PA 13 MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-5392 "TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II" APLA008494-PA 10 KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7187;Reactome: R-HSA-69205;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7210 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" APLA012554-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA015298-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" APLA003949-PA 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" APLA008825-PA 4 Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" APLA009078-PA 12 KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7416 "Arachidonic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)" APLA003156-PA 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" APLA002447-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA006726-PA 8 MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217 "Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Purine salvage" APLA003508-PA 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" APLA001187-PA 9 MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis" APLA004141-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" APLA009841-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA000670-PA 9 Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" APLA009187-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA007913-PA 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" APLA004123-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA004794-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA005576-PA 3 KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271 "Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism" APLA004760-PA 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" APLA002832-PA 29 Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862 "SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK" APLA010986-PA 29 Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-73762 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation" APLA007887-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" APLA000615-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA005246-PA 9 Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" APLA006822-PA 6 MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221 "Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)" APLA001538-PA 3 KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217 "Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage" APLA014986-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA002883-PA 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" APLA006450-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA007181-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" APLA007164-PA 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" APLA000287-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291 "HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C" APLA007125-PA 6 Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" APLA003058-PA 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" APLA011813-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA002389-PA 8 KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171 "Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis" APLA002281-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA011795-PA 12 Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery" APLA007447-PA 4 Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300 "Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors" APLA008152-PA 9 Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" APLA008750-PA 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" APLA012013-PA 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" APLA003679-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA008280-PA 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" APLA008429-PA 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" APLA012508-PA 5 MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18 "Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism" APLA007154-PA 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" APLA012196-PA 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA002480-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" APLA014094-PA 20 KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"mTOR signalling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy" APLA007993-PA 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate" APLA009125-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA008458-PA 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" APLA003644-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" APLA006690-PA 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand" APLA004697-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA014338-PA 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA008641-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA" APLA002227-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA009723-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" APLA008684-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA013751-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA010365-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" APLA013190-PA 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606 "Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" APLA004180-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA014770-PA 7 Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12 "Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)" APLA008887-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" APLA001644-PA 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" APLA003571-PA 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" APLA014320-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" APLA003100-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA000631-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA001624-PA 29 Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167160 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" APLA009374-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA014240-PA 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" APLA001194-PA 8 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER" APLA003575-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" APLA013276-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA008576-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA001670-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" APLA004983-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA006200-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" APLA003102-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA007396-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA010137-PA 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" APLA009495-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" APLA014471-PA 14 MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8053 "Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II" APLA013397-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" APLA006828-PA 6 MetaCyc: PWY-6731;MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-7238 "Starch degradation III";"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II" APLA007018-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA014306-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA005669-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA007908-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" APLA002139-PA 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" APLA000555-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA009849-PA 13 MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;Reactome: R-HSA-74259;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9 "Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism" APLA007601-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA005249-PA 9 Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-2871809 "VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization" APLA014952-PA 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072 "D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization" APLA011035-PA 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" APLA006933-PA 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex" APLA009740-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" APLA009513-PA 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" APLA003262-PA 14 Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1 "Respiratory electron transport";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation" APLA013213-PA 5 KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" APLA013069-PA 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" APLA012563-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA014096-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA005140-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA010434-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" APLA001970-PA 33 MetaCyc: PWY-7118;MetaCyc: PWY-6313;MetaCyc: PWY-5078;MetaCyc: PWY-7798;MetaCyc: PWY-7396;MetaCyc: PWY-6871;MetaCyc: PWY-5057;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5486;MetaCyc: PWY-7013;KEGG: 00350+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6333;KEGG: 00592+1.1.1.1;Reactome: R-HSA-71384;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00625+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5082;MetaCyc: PWY-6342;KEGG: 00071+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-1801;MetaCyc: PWY-3162 "Chitin degradation to ethanol";"Serotonin degradation";"L-isoleucine degradation II";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II";"Glycine, serine and threonine metabolism";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol II";"(S)-propane-1,2-diol degradation";"Tyrosine metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Acetaldehyde biosynthesis I";"alpha-Linolenic acid metabolism";"Ethanol oxidation";"Retinol metabolism";"L-leucine degradation III";"Chloroalkane and chloroalkene degradation";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"Naphthalene degradation";"Salidroside biosynthesis";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol I";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"L-methionine degradation III";"Noradrenaline and adrenaline degradation";"Fatty acid degradation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"L-tryptophan degradation V (side chain pathway)" APLA000168-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA010598-PA 6 Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" APLA006117-PA 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" APLA007052-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" APLA011710-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA013208-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" APLA001587-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" APLA011333-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA014042-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" APLA014999-PA 32 Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-77075 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE" APLA015391-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA003938-PA 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" APLA006443-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" APLA014842-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA014896-PA 40 KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-7778;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7401;MetaCyc: PWY-5136;KEGG: 00623+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-5789;MetaCyc: PWY-7007;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6583;MetaCyc: PWY-6945;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17 "Valine, leucine and isoleucine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid beta-oxidation II (plant peroxisome)";"Toluene degradation";"Tryptophan metabolism";"Pyruvate fermentation to butanol II (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Aminobenzoate degradation";"Fatty acid salvage";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Methyl ketone biosynthesis (engineered)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Benzoate degradation";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Caprolactam degradation";"Lysine degradation";"Limonene and pinene degradation" APLA002581-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA003883-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA009588-PA 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" APLA014778-PA 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" APLA012902-PA 5 Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4 "ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" APLA006660-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" APLA000681-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" APLA008209-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" APLA013956-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA002124-PA 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" APLA009561-PA 8 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1" APLA010067-PA 14 Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" APLA011528-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA003393-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" APLA008421-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA009832-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA000025-PA 8 Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;MetaCyc: PWY-5723 "RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Rubisco shunt" APLA004653-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA001965-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA010863-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA004846-PA 13 MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism" APLA000337-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA002834-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA005000-PA 20 Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation" APLA003496-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA008988-PA 8 Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;MetaCyc: PWY-5723 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Rubisco shunt" APLA005402-PA 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" APLA001217-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA011103-PA 5 Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-936440 "TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling" APLA014036-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" APLA004851-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA004238-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" APLA011141-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA002404-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" APLA000546-PA 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" APLA014472-PA 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" APLA012143-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA008286-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA014130-PA 14 Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2" APLA015353-PA 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" APLA011993-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA011089-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" APLA005523-PA 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" APLA014390-PA 5 KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;MetaCyc: PWY-6168 "Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)" APLA000365-PA 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" APLA011460-PA 7 Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4 "Synthesis of PG";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Glycerophospholipid metabolism" APLA004186-PA 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" APLA014492-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA014838-PA 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" APLA009730-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA002359-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA007916-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" APLA004250-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA006750-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA009349-PA 7 Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" APLA011501-PA 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" APLA002827-PA 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" APLA009871-PA 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" APLA000335-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA014255-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA005783-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA007933-PA 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" APLA007962-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" APLA007145-PA 10 Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" APLA009670-PA 7 Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-8043 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis" APLA012581-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" APLA014461-PA 5 Reactome: R-HSA-71336;Reactome: R-HSA-6798695;MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180 "Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation" APLA007096-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA003808-PA 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351 "Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" APLA010870-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA003602-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA008326-PA 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" APLA006915-PA 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" APLA001623-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA009968-PA 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" APLA000120-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA015327-PA 6 Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685 "Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species" APLA010703-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" APLA010094-PA 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" APLA009421-PA 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" APLA002315-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" APLA014259-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" APLA014985-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA002493-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" APLA008361-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA013767-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA006691-PA 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" APLA012510-PA 4 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA013547-PA 8 Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-5663220 "SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins" APLA005469-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA001487-PA 7 Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis" APLA014430-PA 5 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" APLA008230-PA 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" APLA006012-PA 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" APLA011918-PA 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" APLA012891-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA013251-PA 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" APLA008150-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" APLA003469-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA007858-PA 26 Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257 "Kinesins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion" APLA004549-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA008128-PA 4 Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" APLA002636-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA011704-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA009388-PA 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" APLA011721-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" APLA005473-PA 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" APLA000043-PA 5 Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" APLA011132-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA004886-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA005834-PA 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" APLA005701-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA015495-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" APLA011446-PA 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription" APLA003898-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" APLA015000-PA 32 Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648 "FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes" APLA008679-PA 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" APLA008464-PA 6 KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis" APLA006970-PA 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus" APLA000743-PA 52 Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-167242;Reactome: R-HSA-1834949;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-112382 "Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Cytosolic sensors of pathogen-associated DNA";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex" APLA010535-PA 12 KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1 "Thermogenesis";"Macroautophagy";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway" APLA004356-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" APLA003488-PA 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" APLA015095-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA004838-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA007751-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" APLA015031-PA 26 Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-389977 "Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Aggrephagy";"Post-chaperonin tubulin folding pathway" APLA000049-PA 5 Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" APLA010000-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA014545-PA 29 Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-3371453 "Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response" APLA008244-PA 6 MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3 "Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate" APLA002792-PA 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" APLA004171-PA 6 Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" APLA008704-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" APLA012686-PA 14 MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7587 "Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)" APLA009042-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA000929-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA011144-PA 5 Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357 "VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling" APLA015228-PA 12 Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380259 "Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes" APLA004528-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA003597-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA011610-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" APLA003703-PA 1 Reactome: R-HSA-1483255 "PI Metabolism" APLA007850-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA003812-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA002083-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" APLA008612-PA 9 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"DNA replication initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere" APLA006345-PA 4 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation" APLA014051-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" APLA000738-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA004368-PA 5 Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5649702 "Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" APLA004850-PA 19 Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-5625970;Reactome: R-HSA-5663220;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-8964616;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097 "Rho GTPase cycle";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"RHO GTPases activate KTN1";"RHO GTPases Activate Formins";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"G beta:gamma signalling through CDC42";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"Myogenesis";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway" APLA000848-PA 3 Reactome: R-HSA-433137;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Sodium-coupled sulphate, di- and tri-carboxylate transporters";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism" APLA008849-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA014157-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA002666-PA 8 Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"Photosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" APLA004845-PA 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" APLA006009-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" APLA011535-PA 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" APLA005365-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" APLA006989-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA003264-PA 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" APLA011893-PA 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801 "Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD" APLA014620-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA003691-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA009922-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001267-PA 13 KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1 "Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Drug metabolism - other enzymes" APLA007857-PA 31 Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-6282;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-5366;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-7664;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;MetaCyc: PWY-5973;MetaCyc: PWY-5142;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-7663;MetaCyc: PWY-8049 "Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Petroselinate biosynthesis";"";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"Cis-vaccenate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis" APLA001633-PA 22 Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5467337 "Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding" APLA001562-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA013034-PA 1 MetaCyc: PWY-6938 "NADH repair" APLA005363-PA 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" APLA002418-PA 12 MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-7230 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)" APLA013745-PA 24 KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;Reactome: R-HSA-165158;Reactome: R-HSA-114604;Reactome: R-HSA-5607764;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Thermogenesis";"Integrin signaling";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activation of AKT2";"GPVI-mediated activation cascade";"CLEC7A (Dectin-1) signaling";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"RSK activation";"Downstream TCR signaling";"RHO GTPases activate PKNs";"Relaxin signaling pathway" APLA007970-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA000660-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA003653-PA 13 Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-983695 "Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" APLA002881-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" APLA008290-PA 9 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" APLA006113-PA 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" APLA003615-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA007650-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA012202-PA 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" APLA011505-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" APLA004972-PA 6 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series" APLA002547-PA 5 Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)" APLA006586-PA 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" APLA007488-PA 9 Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis" APLA015214-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA005175-PA 5 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" APLA012032-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA011533-PA 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" APLA007143-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA000185-PA 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" APLA008734-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" APLA011729-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" APLA007638-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA009742-PA 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" APLA002526-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA003021-PA 12 Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343 "Glycogen synthesis";"Stachyose degradation";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I" APLA000030-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" APLA009692-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA000184-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA011044-PA 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" APLA003270-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA001298-PA 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" APLA013306-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA007487-PA 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695 "STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation" APLA014924-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA000577-PA 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" APLA000059-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" APLA013224-PA 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" APLA001680-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" APLA013702-PA 14 Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128 "Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling" APLA003986-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" APLA006567-PA 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" APLA003286-PA 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" APLA009824-PA 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" APLA008803-PA 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" APLA012476-PA 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" APLA005591-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA005797-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" APLA013820-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA002584-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" APLA000465-PA 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA002552-PA 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" APLA014473-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA001125-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" APLA002256-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA015229-PA 4 Reactome: R-HSA-163210;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Respiratory electron transport";"Complex I biogenesis";"Cristae formation" APLA004385-PA 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" APLA008907-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" APLA014431-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" APLA006848-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA009527-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA003001-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA006555-PA 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" APLA003149-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA004124-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA013670-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA007030-PA 19 Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-6802955 "Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF" APLA004887-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" APLA000369-PA 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" APLA013591-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" APLA004323-PA 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" APLA009112-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA008824-PA 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" APLA014953-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" APLA012224-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" APLA010640-PA 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" APLA010662-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA014038-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" APLA003082-PA 13 Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-216083 "Crosslinking of collagen fibrils";"Extracellular matrix organization";"Laminin interactions";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Integrin cell surface interactions" APLA007021-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA002575-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA000684-PA 19 Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-7115;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37 "Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism" APLA009647-PA 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" APLA014241-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA003896-PA 10 Reactome: R-HSA-916853;MetaCyc: PWY-5022;MetaCyc: PWY-6537;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19 "Degradation of GABA";"4-aminobutanoate degradation V";"4-aminobutanoate degradation II";"Propanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation III";"Butanoate metabolism";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism" APLA011453-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" APLA015473-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" APLA000832-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA013005-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA006184-PA 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" APLA004739-PA 4 Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism" APLA014062-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA005756-PA 56 Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-195253 "ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex" APLA003070-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA008439-PA 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes" APLA002625-PA 16 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" APLA008422-PA 3 MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78 "D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" APLA004097-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA004324-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA006015-PA 5 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" APLA000878-PA 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" APLA005796-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" APLA010039-PA 4 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" APLA005101-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA007407-PA 6 Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204 "Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol" APLA007969-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" APLA013647-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" APLA007436-PA 4 Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis" APLA011959-PA 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" APLA013300-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA002004-PA 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA000289-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" APLA014464-PA 1 Reactome: R-HSA-1483101 "Synthesis of PS" APLA000198-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA010316-PA 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" APLA011745-PA 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" APLA000866-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA008936-PA 7 MetaCyc: PWY-7282;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism" APLA014577-PA 13 Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842 "Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II" APLA009721-PA 4 Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170 "ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions" APLA005405-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" APLA008549-PA 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" APLA014136-PA 5 Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" APLA007417-PA 11 Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway" APLA008675-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA007172-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA004889-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA003816-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" APLA001209-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" APLA005867-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" APLA015388-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" APLA007986-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA007938-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571 "Neutrophil degranulation";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)" APLA001529-PA 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" APLA002583-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" APLA011732-PA 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA002282-PA 11 MetaCyc: PWY-6608;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-5695 "Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Purine metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation" APLA005907-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA004000-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" APLA009858-PA 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" APLA004194-PA 4 Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37 "SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism" APLA009107-PA 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" APLA005368-PA 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" APLA005141-PA 29 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation" APLA001944-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" APLA002186-PA 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" APLA002231-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA002129-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA004063-PA 1 Reactome: R-HSA-419771 "Opsins" APLA010633-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001570-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" APLA004448-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" APLA004307-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA011894-PA 9 Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" APLA010064-PA 14 MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I" APLA015384-PA 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER" APLA005504-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA005404-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" APLA008085-PA 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" APLA004285-PA 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-5826 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis" APLA011061-PA 6 Reactome: R-HSA-9615017;MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" APLA012810-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA012579-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA001114-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA005999-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" APLA013074-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA008283-PA 11 Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"DNA replication initiation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis" APLA007550-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA013383-PA 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" APLA010013-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA004075-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" APLA013787-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA004126-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA005265-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" APLA009708-PA 27 Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377 "NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of SUMOylation proteins" APLA013357-PA 26 Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-983189 "Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Kinesins" APLA015026-PA 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" APLA010605-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" APLA010140-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA004907-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" APLA005745-PA 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" APLA004282-PA 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" APLA009944-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA001457-PA 7 Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events" APLA012812-PA 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" APLA010999-PA 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA009142-PA 10 MetaCyc: PWY-7187;Reactome: R-HSA-69205;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-3841;MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate" APLA002140-PA 44 Reactome: R-HSA-6811558;Reactome: R-HSA-3371453;Reactome: R-HSA-5654732;Reactome: R-HSA-881907;Reactome: R-HSA-8943724;Reactome: R-HSA-74749;Reactome: R-HSA-445144;Reactome: R-HSA-202670;Reactome: R-HSA-170968;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-162658;Reactome: R-HSA-198753;Reactome: R-HSA-6802948;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-444257;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-456926;Reactome: R-HSA-879415;Reactome: R-HSA-2029482;Reactome: R-HSA-5674135;Reactome: R-HSA-2871796;Reactome: R-HSA-982772;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5654733;Reactome: R-HSA-6802952;Reactome: R-HSA-2559580;Reactome: R-HSA-5668599;Reactome: R-HSA-6802946;Reactome: R-HSA-5674499;Reactome: R-HSA-9649948;Reactome: R-HSA-2559585;Reactome: R-HSA-450341;Reactome: R-HSA-9635465;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9627069;Reactome: R-HSA-112409;Reactome: R-HSA-9634638;Reactome: R-HSA-6802955;Reactome: R-HSA-2559582;Reactome: R-HSA-375165 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of HSF1-mediated heat shock response";"Negative regulation of FGFR3 signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of PTEN gene transcription";"Signal attenuation";"Signal transduction by L1";"ERKs are inactivated";"Frs2-mediated activation";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"ERK/MAPK targets";"Signaling by high-kinase activity BRAF mutants";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"RSK activation";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Thrombin signalling through proteinase activated receptors (PARs)";"Advanced glycosylation endproduct receptor signaling";"Regulation of actin dynamics for phagocytic cup formation";"MAP2K and MAPK activation";"FCERI mediated MAPK activation";"Growth hormone receptor signaling";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Negative regulation of FGFR4 signaling";"Signaling by BRAF and RAF fusions";"Oxidative Stress Induced Senescence";"RHO GTPases Activate NADPH Oxidases";"Signaling by moderate kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Oncogene Induced Senescence";"Activation of the AP-1 family of transcription factors";"Suppression of apoptosis";"mTOR signaling pathway";"Regulation of the apoptosome activity";"RAF-independent MAPK1/3 activation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Senescence-Associated Secretory Phenotype (SASP)";"NCAM signaling for neurite out-growth" APLA001203-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" APLA015291-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA004634-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" APLA010572-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA011624-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" APLA002336-PA 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" APLA003014-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA001150-PA 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" APLA000853-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" APLA005706-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" APLA002127-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" APLA003605-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" APLA001679-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" APLA003620-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" APLA013862-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA010175-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" APLA004463-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" APLA000012-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" APLA005086-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" APLA001556-PA 4 Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039 "Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex" APLA007967-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA003193-PA 28 Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511 "Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation" APLA015273-PA 4 Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane" APLA010332-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA008613-PA 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA" APLA012795-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA000704-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" APLA003999-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" APLA004561-PA 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" APLA009884-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" APLA003509-PA 18 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA001775-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA008078-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" APLA011145-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA008047-PA 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" APLA012176-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA002444-PA 27 Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749 "Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs" APLA000140-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA010585-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA011969-PA 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism" APLA007753-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" APLA013237-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA005906-PA 5 Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37 "SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism" APLA015489-PA 14 KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781 "Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)" APLA014335-PA 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" APLA000884-PA 20 Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397 "Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER" APLA007166-PA 10 KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922 "Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Butanoate metabolism";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I" APLA012635-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA006751-PA 5 KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" APLA005019-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" APLA014137-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA008446-PA 26 Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin" APLA002525-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA014040-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" APLA009810-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA007020-PA 5 KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" APLA010171-PA 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" APLA008732-PA 7 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" APLA005397-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA013964-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" APLA007847-PA 4 KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" APLA014538-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA003690-PA 11 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human papillomavirus infection" APLA009814-PA 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling" APLA001710-PA 1 Reactome: R-HSA-525793 "Myogenesis" APLA002420-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA004988-PA 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" APLA011831-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" APLA009342-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA003502-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA003353-PA 11 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange" APLA014159-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA000963-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA001035-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA004140-PA 5 Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-3371571 "mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation" APLA010381-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" APLA015091-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA014830-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA011113-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA003487-PA 5 MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6892 "Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)" APLA005031-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA007609-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA011862-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA010173-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" APLA010583-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA010645-PA 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism" APLA010287-PA 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" APLA012074-PA 4 Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation" APLA009255-PA 9 Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection" APLA006720-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" APLA011923-PA 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" APLA003650-PA 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic" APLA006380-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA009423-PA 4 Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA" APLA000700-PA 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" APLA003784-PA 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" APLA000960-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA008067-PA 8 Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" APLA014355-PA 8 Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" APLA006577-PA 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" APLA014958-PA 10 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" APLA001551-PA 52 Reactome: R-HSA-76066;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167290 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"mRNA Capping";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation" APLA002559-PA 4 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs" APLA001290-PA 27 Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377 "NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins" APLA008987-PA 56 Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5632684 "Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state" APLA002135-PA 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" APLA014955-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" APLA007957-PA 4 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" APLA008159-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA003566-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" APLA015153-PA 8 Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826 "Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism" APLA004795-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA011684-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" APLA014841-PA 26 Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-1362277;Reactome: R-HSA-110320;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6804114;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-69205;Reactome: R-HSA-8866654;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-4615885 "Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Transcription of E2F targets under negative control by DREAM complex";"Translesion Synthesis by POLH";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Translesion synthesis by POLI";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"G1/S-Specific Transcription";"E3 ubiquitin ligases ubiquitinate target proteins";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA replication proteins" APLA002856-PA 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" APLA011670-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" APLA005232-PA 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" APLA014443-PA 15 Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" APLA001935-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA005777-PA 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" APLA000522-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA010466-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA015390-PA 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" APLA009719-PA 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" APLA000133-PA 5 MetaCyc: PWY-7279;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692 "Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation" APLA000824-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA002082-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" APLA002689-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA010791-PA 57 Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236 "Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" APLA011230-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA005730-PA 13 KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-5497 "One carbon pool by folate";"Folate polyglutamylation";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"L-histidine degradation III";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)" APLA014026-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" APLA012797-PA 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" APLA006510-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA005305-PA 4 Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829 "CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" APLA008443-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA004792-PA 3 Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517 "Ca2+ pathway";"cGMP effects";"Rap1 signalling" APLA000959-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" APLA004273-PA 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" APLA009479-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA009488-PA 5 Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" APLA008652-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" APLA009971-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA012338-PA 24 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Gap junction assembly";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin" APLA000699-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" APLA007256-PA 3 Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" APLA013590-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" APLA005447-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA013080-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA005622-PA 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" APLA005245-PA 17 Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-163359;Reactome: R-HSA-432040 "Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins" APLA010545-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" APLA013003-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA003894-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA004976-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA011712-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA010657-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" APLA005894-PA 6 Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165 "SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway" APLA005654-PA 1 Reactome: R-HSA-70350 "Fructose catabolism" APLA011123-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA003183-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA001105-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" APLA012736-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins" APLA008705-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA012401-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" APLA006163-PA 1 Reactome: R-HSA-1483148 "Synthesis of PG" APLA000171-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA003558-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA009835-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA007047-PA 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" APLA004548-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" APLA004393-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" APLA006607-PA 30 Reactome: R-HSA-917937;Reactome: R-HSA-1170546;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-5684264;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-2122947;Reactome: R-HSA-69231;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5676590 "Iron uptake and transport";"Prolactin receptor signaling";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Neddylation";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Cyclin D associated events in G1";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling" APLA008347-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" APLA015239-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA005262-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA003818-PA 10 MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-7003 "Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol" APLA013223-PA 56 Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902 "CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity" APLA008348-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" APLA005364-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA011678-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" APLA008217-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" APLA000912-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA005787-PA 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" APLA009851-PA 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" APLA015268-PA 15 MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5723;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221 "Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Rubisco shunt";"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)" APLA003234-PA 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" APLA014029-PA 10 Reactome: R-HSA-156827;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-381042 "L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"PERK regulates gene expression" APLA000186-PA 4 Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695 "Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation" APLA002049-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA013323-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" APLA014624-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" APLA006659-PA 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" APLA015036-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA008872-PA 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion" APLA009431-PA 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" APLA004009-PA 7 MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6737;Reactome: R-HSA-70221 "Starch degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)" APLA005259-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA006385-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA001036-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA014667-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA010474-PA 5 MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" APLA004042-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" APLA006779-PA 6 MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism" APLA007647-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA003267-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA015296-PA 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" APLA013706-PA 10 KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11 "Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway" APLA000721-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-6783310 "COPII-mediated vesicle transport";"Fanconi Anemia Pathway" APLA003517-PA 8 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" APLA004551-PA 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" APLA012402-PA 7 MetaCyc: PWY-7836;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7841 "Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis" APLA005856-PA 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" APLA004655-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA010009-PA 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" APLA003990-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA002880-PA 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" APLA001906-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA009417-PA 26 Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295 "Aggrephagy";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Cilium Assembly";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation" APLA014982-PA 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" APLA000169-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" APLA004329-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" APLA000688-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" APLA002288-PA 179 Reactome: R-HSA-156827;Reactome: R-HSA-8854050;Reactome: R-HSA-5357905;Reactome: R-HSA-5610783;Reactome: R-HSA-3769402;Reactome: R-HSA-5693565;Reactome: R-HSA-174113;Reactome: R-HSA-8866654;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-6781827;Reactome: R-HSA-6791226;Reactome: R-HSA-9014325;Reactome: R-HSA-2173788;Reactome: R-HSA-6782210;Reactome: R-HSA-180585;Reactome: R-HSA-975110;Reactome: R-HSA-6783310;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-8875360;Reactome: R-HSA-450302;Reactome: R-HSA-8866652;Reactome: R-HSA-5685942;Reactome: R-HSA-69017;Reactome: R-HSA-5655862;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-2979096;Reactome: R-HSA-5205685;Reactome: R-HSA-1799339;Reactome: R-HSA-5696397;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2173796;Reactome: R-HSA-110312;Reactome: R-HSA-9633012;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5654726;Reactome: R-HSA-72689;Reactome: R-HSA-69231;Reactome: R-HSA-110314;Reactome: R-HSA-72764;Reactome: R-HSA-6804757;Reactome: R-HSA-9033241;Reactome: R-HSA-8856828;Reactome: R-HSA-917937;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-5654733;Reactome: R-HSA-5689901;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-6804760;Reactome: R-HSA-2894862;Reactome: R-HSA-209560;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-977225;Reactome: R-HSA-195253;Reactome: R-HSA-2644606;Reactome: R-HSA-9615710;Reactome: R-HSA-1169091;Reactome: R-HSA-209543;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-3322077;Reactome: R-HSA-975144;Reactome: R-HSA-174490;Reactome: R-HSA-936440;Reactome: R-HSA-937042;Reactome: R-HSA-1234176;Reactome: R-HSA-917729;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8948747;Reactome: R-HSA-5610780;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-156902;Reactome: R-HSA-5676590;Reactome: R-HSA-445989;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-901032;Reactome: R-HSA-201681;Reactome: R-HSA-8849469;Reactome: R-HSA-2122947;Reactome: R-HSA-936964;Reactome: R-HSA-8856825;Reactome: R-HSA-1236382;Reactome: R-HSA-937039;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-8876493;Reactome: R-HSA-5675221;Reactome: R-HSA-2173791;Reactome: R-HSA-174084;Reactome: R-HSA-5689877;Reactome: R-HSA-174184;Reactome: R-HSA-3134975;Reactome: R-HSA-2559585;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-5696395;Reactome: R-HSA-110320;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5654727;Reactome: R-HSA-2173795;Reactome: R-HSA-6781823;Reactome: R-HSA-1236974;Reactome: R-HSA-72706;Reactome: R-HSA-69541;Reactome: R-HSA-5689896;Reactome: R-HSA-975957;Reactome: R-HSA-5610785;Reactome: R-HSA-532668;Reactome: R-HSA-450408;Reactome: R-HSA-5654732;Reactome: R-HSA-2565942;Reactome: R-HSA-2672351;Reactome: R-HSA-2408557;Reactome: R-HSA-9637628;Reactome: R-HSA-2122948;Reactome: R-HSA-182971;Reactome: R-HSA-937041;Reactome: R-HSA-2691232;Reactome: R-HSA-5675482;Reactome: R-HSA-5656169;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-168927;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-168928;Reactome: R-HSA-175474;Reactome: R-HSA-4641263;Reactome: R-HSA-9013507;Reactome: R-HSA-6807004;Reactome: R-HSA-5693607;Reactome: R-HSA-205043;Reactome: R-HSA-2559580;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-9613829;Reactome: R-HSA-168638;Reactome: R-HSA-162588;Reactome: R-HSA-9636383;Reactome: R-HSA-5632684;Reactome: R-HSA-912631;Reactome: R-HSA-1169408;Reactome: R-HSA-450321;Reactome: R-HSA-8939236;Reactome: R-HSA-5684264;Reactome: R-HSA-192823;Reactome: R-HSA-1358803;Reactome: R-HSA-5357956;Reactome: R-HSA-1253288;Reactome: R-HSA-4608870;Reactome: R-HSA-5696394;Reactome: R-HSA-8948751;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-9013973;Reactome: R-HSA-975956;Reactome: R-HSA-3785653;Reactome: R-HSA-8863795;Reactome: R-HSA-202424;Reactome: R-HSA-1295596 "L13a-mediated translational silencing of Ceruloplasmin expression";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of TNFR1 signaling";"Degradation of GLI2 by the proteasome";"Deactivation of the beta-catenin transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SCF-beta-TrCP mediated degradation of Emi1";"E3 ubiquitin ligases ubiquitinate target proteins";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Major pathway of rRNA processing in the nucleolus and cytosol";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of TGF-beta receptor signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Vif-mediated degradation of APOBEC3G";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Fanconi Anemia Pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"InlB-mediated entry of Listeria monocytogenes into host cell";"activated TAK1 mediates p38 MAPK activation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"HDR through Homologous Recombination (HRR)";"CDK-mediated phosphorylation and removal of Cdc6";"Translesion synthesis by POLK";"Aggrephagy";"Separation of Sister Chromatids";"Neddylation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Pink/Parkin Mediated Mitophagy";"SRP-dependent cotranslational protein targeting to membrane";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Translesion synthesis by REV1";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of FGFR1 signaling";"Formation of a pool of free 40S subunits";"Cyclin D associated events in G1";"Recognition of DNA damage by PCNA-containing replication complex";"Eukaryotic Translation Termination";"Regulation of TP53 Degradation";"Peroxisomal protein import";"Clathrin-mediated endocytosis";"Iron uptake and transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of FGFR4 signaling";"Metalloprotease DUBs";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Degradation of AXIN";"Regulation of TP53 Activity through Methylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NF-kB is activated and signals survival";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Amyloid fiber formation";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Late endosomal microautophagy";"Activation of NF-kappaB in B cells";"p75NTR recruits signalling complexes";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Glycogen synthesis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Membrane binding and targetting of GAG proteins";"Negative regulators of DDX58/IFIH1 signaling";"IRAK2 mediated activation of TAK1 complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Endosomal Sorting Complex Required For Transport (ESCRT)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Regulation of PTEN localization";"Degradation of GLI1 by the proteasome";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Peptide chain elongation";"NIK-->noncanonical NF-kB signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"ER Quality Control Compartment (ERQC)";"TCF dependent signaling in response to WNT";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Cargo recognition for clathrin-mediated endocytosis";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"IRAK1 recruits IKK complex";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"InlA-mediated entry of Listeria monocytogenes into host cells";"Negative regulation of MAPK pathway";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Josephin domain DUBs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of innate immune responses to cytosolic DNA";"Oncogene Induced Senescence";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"Formation of Incision Complex in GG-NER";"Translesion Synthesis by POLH";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Negative regulation of FGFR2 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of TC-NER Pre-Incision Complex";"ER-Phagosome pathway";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Stabilization of p53";"Ovarian tumor domain proteases";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of FGFR3 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Stimuli-sensing channels";"Selenocysteine synthesis";"Modulation by Mtb of host immune system";"Activated NOTCH1 Transmits Signal to the Nucleus";"EGFR downregulation";"IKK complex recruitment mediated by RIP1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of necroptotic cell death";"Termination of translesion DNA synthesis";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1, RIP1-mediated IKK complex recruitment";"Translesion synthesis by POLI";"Dual incision in TC-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Assembly Of The HIV Virion";"Regulation of FZD by ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of MET activity";"Processing of DNA double-strand break ends";"NRIF signals cell death from the nucleus";"Oxidative Stress Induced Senescence";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Chaperone Mediated Autophagy";"NOD1/2 Signaling Pathway";"Budding and maturation of HIV virion";"Prevention of phagosomal-lysosomal fusion";"Hedgehog 'on' state";"Regulation of signaling by CBL";"ISG15 antiviral mechanism";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Viral mRNA Translation";"Downregulation of ERBB2:ERBB3 signaling";"TNFR1-induced NFkappaB signaling pathway";"Downregulation of ERBB4 signaling";"Asymmetric localization of PCP proteins";"DNA Damage Recognition in GG-NER";"Regulation of PTEN stability and activity";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB2 signaling";"Downstream TCR signaling";"Spry regulation of FGF signaling" APLA010534-PA 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" APLA009452-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA013622-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" APLA008605-PA 5 MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" APLA006339-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" APLA001606-PA 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" APLA008263-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" APLA000812-PA 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" APLA008935-PA 6 KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" APLA002535-PA 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" APLA010349-PA 5 MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis" APLA012079-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" APLA013639-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA013963-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA013653-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" APLA012987-PA 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" APLA000940-PA 16 Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-8853884 "Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX" APLA006049-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" APLA011784-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" APLA002118-PA 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" APLA013597-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA014013-PA 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" APLA007319-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" APLA014865-PA 1 Reactome: R-HSA-977443 "GABA receptor activation" APLA003559-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" APLA012609-PA 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" APLA006758-PA 1 Reactome: R-HSA-525793 "Myogenesis" APLA002656-PA 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" APLA006975-PA 56 Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534 "Degradation of GLI2 by the proteasome";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4" APLA012530-PA 5 MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" APLA009863-PA 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" APLA001849-PA 3 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import" APLA012726-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" APLA003086-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA004504-PA 57 Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling" APLA007701-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" APLA009149-PA 14 Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis" APLA006867-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA001350-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA003587-PA 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" APLA004174-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" APLA014138-PA 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158 "Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V" APLA008297-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA007672-PA 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" APLA011335-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA007698-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA013918-PA 5 Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-9646399 "Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Amyloid fiber formation";"Aggrephagy" APLA007917-PA 6 Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930 "Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor" APLA002314-PA 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" APLA006993-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA015287-PA 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" APLA004645-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" APLA014742-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA002937-PA 27 Reactome: R-HSA-975956;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-8851708;Reactome: R-HSA-159230;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-77588;Reactome: R-HSA-72203;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-77595 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Signaling by FGFR2 IIIa TM";"Transport of the SLBP Dependant Mature mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs" APLA007929-PA 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" APLA011273-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA010823-PA 6 MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-4381 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)" APLA010387-PA 14 Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110320 "HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Dual incision in TC-NER";"Translesion Synthesis by POLH" APLA009344-PA 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" APLA015064-PA 9 Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" APLA014746-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA003731-PA 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" APLA007491-PA 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis" APLA003152-PA 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" APLA007458-PA 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" APLA011585-PA 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" APLA002065-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA003544-PA 19 Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-8964046 "Chylomicron assembly";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"LDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class B Receptors";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"VLDL clearance" APLA005017-PA 16 Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-141430 "APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex" APLA006786-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" APLA010091-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA015028-PA 56 Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8939236 "Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" APLA011000-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA000726-PA 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" APLA002051-PA 2 KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5 "Fructose and mannose metabolism";"Pentose and glucuronate interconversions" APLA010578-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" APLA005996-PA 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" APLA007710-PA 4 Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" APLA009504-PA 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" APLA004453-PA 5 Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" APLA002850-PA 1 Reactome: R-HSA-211981 "Xenobiotics" APLA010350-PA 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" APLA005611-PA 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" APLA000970-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" APLA007645-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA010569-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA015235-PA 10 MetaCyc: PWY-5839;MetaCyc: PWY-5891;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-5895;MetaCyc: PWY-5844;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996 "Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I" APLA009666-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" APLA008756-PA 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" APLA011767-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" APLA000816-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA001432-PA 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" APLA012790-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" APLA005952-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" APLA007395-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA004844-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA004984-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" APLA007049-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" APLA010202-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" APLA012865-PA 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" APLA008362-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA008151-PA 8 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"MASTL Facilitates Mitotic Progression";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" APLA001971-PA 5 Reactome: R-HSA-199220;MetaCyc: PWY-6012;MetaCyc: PWY-6289;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7 "Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis" APLA013239-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" APLA001848-PA 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" APLA015058-PA 33 Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" APLA012681-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA007467-PA 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22 "Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" APLA010437-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-611105 "HATs acetylate histones";"Respiratory electron transport" APLA011440-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA001862-PA 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" APLA001905-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA004542-PA 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" APLA008250-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA007205-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA000476-PA 9 MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003 "Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol" APLA008288-PA 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" APLA015356-PA 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" APLA007538-PA 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" APLA001857-PA 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" APLA005659-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA012828-PA 6 Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-2173788 "Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling" APLA003133-PA 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" APLA005085-PA 8 MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;KEGG: 00630+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-7733;MetaCyc: PWY-7734 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis" APLA001123-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" APLA005264-PA 15 Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017 "APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6" APLA007979-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA001974-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA012425-PA 8 MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" APLA007679-PA 9 MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042 "Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)" APLA004823-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA010507-PA 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" APLA003064-PA 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" APLA013061-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" APLA008125-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA002090-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" APLA003678-PA 19 Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-381426 "Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Chylomicron assembly";"VLDL clearance";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class B Receptors";"LDL remodeling";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" APLA011026-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA000500-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" APLA008758-PA 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" APLA009848-PA 15 Reactome: R-HSA-9652282;Reactome: R-HSA-9665233;Reactome: R-HSA-9665250;Reactome: R-HSA-9665244;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-1236382 "Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants" APLA011048-PA 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" APLA003253-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA001977-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA014540-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA008398-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" APLA012308-PA 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" APLA012911-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" APLA000663-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA008349-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" APLA010016-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA001089-PA 4 Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168 "Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation" APLA006899-PA 32 Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167290 "Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"mRNA Capping";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation" APLA008823-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" APLA004642-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA003850-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA005781-PA 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA001536-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA010134-PA 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" APLA005358-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" APLA010423-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA010601-PA 15 Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896 "Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases" APLA014309-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA003473-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA006070-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" APLA012999-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA001684-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" APLA012329-PA 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" APLA005222-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" APLA001158-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA006903-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA002967-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" APLA013969-PA 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" APLA000677-PA 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" APLA010172-PA 7 Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" APLA008971-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" APLA006854-PA 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA003430-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA009743-PA 7 MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659 "Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis" APLA008834-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" APLA000630-PA 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" APLA014914-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" APLA004700-PA 6 Reactome: R-HSA-381426;Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex" APLA000605-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA004503-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" APLA007229-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" APLA013807-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" APLA004200-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA006554-PA 14 MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-500657;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" APLA003637-PA 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" APLA004881-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" APLA013630-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" APLA004629-PA 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" APLA011378-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA008228-PA 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" APLA003713-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" APLA001632-PA 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" APLA013610-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA004582-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" APLA010581-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA006392-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA000479-PA 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" APLA002301-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" APLA002458-PA 13 MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)" APLA007060-PA 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" APLA014879-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA002878-PA 27 Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5619107 "SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" APLA002641-PA 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" APLA004537-PA 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" APLA012328-PA 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" APLA002292-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA004835-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA001682-PA 5 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" APLA000905-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" APLA006038-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA007731-PA 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" APLA006390-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" APLA005604-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA002900-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" APLA005630-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" APLA003383-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" APLA014880-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" APLA011621-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" APLA007905-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA005863-PA 7 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" APLA000859-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA001041-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA007221-PA 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" APLA004732-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA014791-PA 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" APLA003680-PA 11 Reactome: R-HSA-381340;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Circadian Clock";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha" APLA013644-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" APLA008637-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA001589-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" APLA014426-PA 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" APLA001796-PA 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" APLA013736-PA 10 Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-2151201 "Respiratory electron transport";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis" APLA005357-PA 7 Reactome: R-HSA-5368286;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA003794-PA 1 MetaCyc: PWY-7379 "Mrna capping II" APLA002192-PA 6 Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1 "Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" APLA004806-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" APLA003947-PA 1 Reactome: R-HSA-9640463 "Wax biosynthesis" APLA009094-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" APLA003190-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA013064-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" APLA008524-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA005154-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA002908-PA 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" APLA001630-PA 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" APLA000948-PA 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" APLA005153-PA 1 Reactome: R-HSA-8949613 "Cristae formation" APLA013577-PA 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" APLA001793-PA 16 Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825 "VLDLR internalisation and degradation";"Recycling pathway of L1";"Formation of annular gap junctions";"LDL clearance";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis" APLA014312-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" APLA010198-PA 24 Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Aggrephagy";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Gap junction assembly";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Kinesins" APLA009855-PA 3 MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217 "Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage" APLA002724-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" APLA013817-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA004182-PA 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" APLA006417-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" APLA011073-PA 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" APLA013154-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA011749-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" APLA003047-PA 14 Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8943723 "Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation" APLA004452-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA012222-PA 3 KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2 "Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism" APLA000956-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA008301-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA002753-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA004330-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA004193-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA012294-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA014357-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" APLA004102-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA002588-PA 1 Reactome: R-HSA-9640463 "Wax biosynthesis" APLA008291-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA012684-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" APLA006599-PA 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" APLA001314-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA010076-PA 9 Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-9657050;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" APLA001816-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA001840-PA 6 Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-69166 "Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate" APLA014065-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA009979-PA 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" APLA013155-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA007864-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" APLA003939-PA 18 KEGG: 00020+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00260+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00310+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00620+1.8.1.4;MetaCyc: PWY-5084;MetaCyc: PWY-5046;Reactome: R-HSA-6783984;Reactome: R-HSA-71403;KEGG: 00010+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71064 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Tryptophan metabolism";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine, serine and threonine metabolism";"Signaling by Retinoic Acid";"Lysine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine degradation";"Citric acid cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism" APLA002453-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA002507-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA001471-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA004744-PA 6 MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism" APLA000291-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA008424-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" APLA011778-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" APLA009139-PA 3 MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8 "L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation" APLA005740-PA 4 KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" APLA010889-PA 7 MetaCyc: PWY-4984;MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;Reactome: R-HSA-70635 "Urea cycle";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine biosynthesis";"Putrescine biosynthesis III";"Urea cycle" APLA008495-PA 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" APLA003151-PA 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" APLA010508-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" APLA015413-PA 1 MetaCyc: PWY-101 "Photosynthesis light reactions" APLA015323-PA 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism" APLA012189-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA001413-PA 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" APLA010945-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001797-PA 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" APLA014354-PA 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" APLA004383-PA 28 Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-389661;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;MetaCyc: PWY-7382;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;KEGG: 00785+2.3.1.181;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;MetaCyc: PWY-6987;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295 "Aggrephagy";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Glyoxylate metabolism and glycine degradation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Lipoate biosynthesis and incorporation IV (yeast)";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Kinesins";"Lipoic acid metabolism";"HCMV Early Events";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Cilium Assembly";"Lipoate biosynthesis and incorporation III (Bacillus)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation" APLA000968-PA 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" APLA011554-PA 2 Reactome: R-HSA-392154;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes" APLA006190-PA 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" APLA012562-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA013467-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" APLA007086-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA002946-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA001378-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA014549-PA 7 Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" APLA005888-PA 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism" APLA015454-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" APLA008842-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA006254-PA 14 MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1 "TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation" APLA002536-PA 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" APLA011325-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA014324-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA008186-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" APLA005484-PA 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" APLA011577-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA005251-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" APLA009245-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA006178-PA 40 MetaCyc: PWY-6945;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6435;MetaCyc: PWY-7778;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6944;MetaCyc: PWY-7654;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5109 "Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Benzoate degradation";"Lysine degradation";"Caprolactam degradation";"Limonene and pinene degradation";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Aminobenzoate degradation";"Fatty acid salvage";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Tryptophan metabolism";"Toluene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Carbon fixation pathways in prokaryotes";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate" APLA008973-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" APLA008271-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" APLA009729-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA007466-PA 5 KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism" APLA011405-PA 9 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" APLA012612-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA006770-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" APLA013308-PA 19 Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-5628897;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-611105;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6790901 "Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TP53 Regulates Metabolic Genes";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Respiratory electron transport";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol" APLA002432-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" APLA010449-PA 16 KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.4;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392 "Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II" APLA002757-PA 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" APLA003280-PA 8 Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" APLA007136-PA 11 Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" APLA001533-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" APLA014444-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" APLA001506-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA011608-PA 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" APLA009093-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" APLA014133-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" APLA003531-PA 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA000004-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA007146-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" APLA014358-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" APLA005176-PA 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" APLA002001-PA 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" APLA008019-PA 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" APLA008018-PA 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" APLA005073-PA 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism" APLA001517-PA 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" APLA008430-PA 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" APLA000056-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" APLA005011-PA 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-1442490 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation" APLA014032-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" APLA004218-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" APLA007091-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA005449-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" APLA009230-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" APLA007174-PA 1 Reactome: R-HSA-70921 "Histidine catabolism" APLA013341-PA 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" APLA013968-PA 56 Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050 "Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" APLA013367-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA004072-PA 1 Reactome: R-HSA-525793 "Myogenesis" APLA003095-PA 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III" APLA007578-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA002693-PA 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" APLA001795-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA008811-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA010639-PA 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" APLA009554-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" APLA000749-PA 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" APLA002375-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" APLA011282-PA 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" APLA004212-PA 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" APLA015248-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA015189-PA 56 Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610780 "SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome" APLA006227-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" APLA002271-PA 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" APLA006672-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" APLA010020-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" APLA005913-PA 5 Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720 "Keratan sulfate degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis" APLA001445-PA 5 Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" APLA003700-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" APLA012775-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA002235-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA002298-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA005945-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA010632-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA012546-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" APLA000226-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA000821-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA003163-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA008588-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" APLA000488-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" APLA014004-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" APLA011023-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA007093-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA014520-PA 40 Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648 "RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Capping";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes" APLA005568-PA 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" APLA001716-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" APLA003770-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" APLA005120-PA 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" APLA006673-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" APLA014772-PA 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" APLA010852-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA005033-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" APLA015063-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA009953-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA006556-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA003892-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA002297-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA010301-PA 8 Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" APLA008653-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" APLA014452-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" APLA001762-PA 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" APLA004208-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" APLA009113-PA 8 Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling" APLA013381-PA 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" APLA007577-PA 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" APLA009512-PA 7 KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" APLA014783-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA003981-PA 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" APLA003546-PA 6 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-156842;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Eukaryotic Translation Elongation";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" APLA013645-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" APLA003983-PA 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" APLA001272-PA 5 MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621 "Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism" APLA004611-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" APLA011740-PA 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" APLA014264-PA 4 Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440 "Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" APLA006341-PA 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" APLA014332-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA010856-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" APLA000540-PA 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" APLA009900-PA 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" APLA007851-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA005258-PA 22 MetaCyc: PWY-7592;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-5080;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7049 "Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)" APLA004904-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" APLA012690-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" APLA002322-PA 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" APLA007924-PA 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" APLA005633-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" APLA003859-PA 8 KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;MetaCyc: PWY-5194;KEGG: 00330+2.5.1.16;KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107;MetaCyc: PWY-5196;MetaCyc: PWY-7377;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Siroheme biosynthesis";"Arginine and proline metabolism";"Porphyrin and chlorophyll metabolism";"Factor 430 biosynthesis";"Cob(ii)yrinate a,c-diamide biosynthesis I (early cobalt insertion)";"Glutathione metabolism" APLA010562-PA 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" APLA009951-PA 3 Reactome: R-HSA-3214847;Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "HATs acetylate histones";"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" APLA014622-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" APLA008748-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA011824-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" APLA012545-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA004506-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA004190-PA 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" APLA005626-PA 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" APLA004147-PA 14 MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-8051 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I" APLA003120-PA 4 MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism" APLA014016-PA 56 Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091 "Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells" APLA011617-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA010436-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA001305-PA 7 MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7185 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I" APLA012691-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA010587-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA014467-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" APLA005077-PA 4 Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" APLA006809-PA 8 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA005391-PA 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" APLA008563-PA 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" APLA015266-PA 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" APLA007536-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" APLA011412-PA 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" APLA013627-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA006632-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" APLA009248-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" APLA000926-PA 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" APLA009662-PA 10 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" APLA007661-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA010655-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" APLA000572-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" APLA001794-PA 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" APLA002558-PA 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" APLA005677-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA007048-PA 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" APLA008659-PA 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand" APLA008323-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" APLA004891-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA004312-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" APLA009711-PA 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" APLA013844-PA 56 Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178 "Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" APLA001165-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA007915-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA006682-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" APLA002378-PA 6 MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I" APLA002696-PA 1 Reactome: R-HSA-5676934 "Protein repair" APLA011085-PA 9 Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801 "HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD" APLA003173-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" APLA005605-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" APLA001296-PA 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate" APLA009926-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA002692-PA 15 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;MetaCyc: PWY-5744;Reactome: R-HSA-166208;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-8943724;MetaCyc: PWY-7115 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Glyoxylate assimilation";"mTORC1-mediated signalling";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"mTOR signalling";"Amino acids regulate mTORC1";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Regulation of PTEN gene transcription";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" APLA005321-PA 11 Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167290 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation" APLA002086-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" APLA002153-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" APLA005565-PA 27 Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins" APLA000123-PA 1 Reactome: R-HSA-8876725 "Protein methylation" APLA000784-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA011523-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA008204-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" APLA012204-PA 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" APLA004432-PA 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321 "mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" APLA002665-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" APLA003749-PA 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" APLA006680-PA 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" APLA006618-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" APLA000215-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" APLA001975-PA 14 KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7416 "Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)" APLA011106-PA 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" APLA006662-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" APLA015182-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA012877-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" APLA013282-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA007863-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" APLA007521-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" APLA006000-PA 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" APLA007155-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA003881-PA 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" APLA000176-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" APLA006388-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA012215-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA008490-PA 25 Reactome: R-HSA-8935964;Reactome: R-HSA-8941858;Reactome: R-HSA-8934593;Reactome: R-HSA-8941332;Reactome: R-HSA-8940973;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8939242;Reactome: R-HSA-8939256;Reactome: R-HSA-8949275;Reactome: R-HSA-8939236;Reactome: R-HSA-8939245;Reactome: R-HSA-8931987;Reactome: R-HSA-8941326;Reactome: R-HSA-8941333;Reactome: R-HSA-8877330;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-8951936;Reactome: R-HSA-8939243;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519 "RUNX1 regulates expression of components of tight junctions";"Regulation of RUNX3 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates bone development";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 regulates p14-ARF";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression" APLA001076-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" APLA000482-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA011846-PA 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" APLA011336-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" APLA000440-PA 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" APLA014833-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" APLA009184-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" APLA006969-PA 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" APLA005323-PA 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" APLA007219-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" APLA008157-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" APLA008966-PA 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" APLA009947-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" APLA011347-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA001289-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" APLA001617-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" APLA012470-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA005278-PA 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" APLA008278-PA 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" APLA001691-PA 26 Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-8866654;Reactome: R-HSA-69205;Reactome: R-HSA-4615885;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-110312;Reactome: R-HSA-1362277;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-6804114;Reactome: R-HSA-5656121 "PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"E3 ubiquitin ligases ubiquitinate target proteins";"G1/S-Specific Transcription";"SUMOylation of DNA replication proteins";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Translesion synthesis by REV1";"Transcription of E2F targets under negative control by DREAM complex";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLI" APLA000447-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA010435-PA 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" APLA006946-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" APLA014539-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" APLA009465-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA011452-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" APLA011128-PA 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" APLA001842-PA 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" APLA005367-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA004588-PA 6 Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685 "Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species" APLA002907-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" APLA014588-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA014162-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA010885-PA 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport" APLA015241-PA 11 Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878 "Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport" APLA011850-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA011430-PA 2 Reactome: R-HSA-8854214;Reactome: R-HSA-8873719 "TBC/RABGAPs";"RAB geranylgeranylation" APLA014160-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA001094-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" APLA000736-PA 8 KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268 "Cysteine and methionine metabolism";"Propanoate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism" APLA010513-PA 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"MHC class II antigen presentation" APLA012114-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" APLA002123-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA004778-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA003820-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA007496-PA 7 Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" APLA001663-PA 8 Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616 "Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication" APLA001541-PA 17 Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-3371453;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Meiotic synapsis";"Regulation of HSF1-mediated heat shock response";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" APLA002551-PA 25 Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Separation of Sister Chromatids";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"HCMV Early Events";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Cilium Assembly";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Kinesins" APLA005948-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA002461-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" APLA006858-PA 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" APLA000054-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" APLA006559-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" APLA004737-PA 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" APLA013151-PA 17 Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-5696397 "Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER" APLA005010-PA 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" APLA001295-PA 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" APLA003817-PA 10 MetaCyc: PWY-8004;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-1042 "Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)" APLA008215-PA 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" APLA004172-PA 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017 "Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" APLA002005-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" APLA004375-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" APLA004223-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" APLA012906-PA 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-380994 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" APLA003048-PA 12 Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes" APLA011360-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA007468-PA 5 MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22 "Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism" APLA009102-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA003736-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" APLA013330-PA 14 MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Butanoate metabolism" APLA013738-PA 17 MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-6627;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1 "Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine catabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism" APLA009176-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA007914-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA013496-PA 17 MetaCyc: PWY-5789;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Aflatoxin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis";"Pyruvate metabolism";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Carnitine metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation" APLA005632-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" APLA009552-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA005929-PA 6 Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987 "Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2" APLA010399-PA 5 Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604 "Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling" APLA000323-PA 11 MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539 "L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism" APLA015417-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA012979-PA 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" APLA001576-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA012317-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA007966-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" APLA012134-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" APLA003953-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA003196-PA 6 Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" APLA014542-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" APLA008923-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" APLA011607-PA 1 Reactome: R-HSA-8964572 "Lipid particle organization" APLA014128-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" APLA008908-PA 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II" APLA013908-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" APLA009724-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA008747-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA000967-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA010314-PA 3 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" APLA006699-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" APLA006869-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA000220-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" APLA014717-PA 4 KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" APLA001458-PA 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" APLA006656-PA 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" APLA002125-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA012883-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome" APLA001157-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" APLA009771-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA001749-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA014037-PA 52 Reactome: R-HSA-73780;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-77075;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-5250924 "RNA Polymerase III Chain Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"HIV Transcription Initiation";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression" APLA010074-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA003272-PA 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" APLA006902-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" APLA000371-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" APLA006785-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" APLA004331-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" APLA001142-PA 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" APLA005427-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" APLA008294-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA006919-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" APLA014515-PA 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" APLA012878-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" APLA009161-PA 8 MetaCyc: PWY-5739;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5740;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639 "GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis" APLA011609-PA 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" APLA000633-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" APLA013278-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" APLA010443-PA 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" APLA008885-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" APLA004085-PA 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions" APLA001864-PA 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" APLA005733-PA 7 Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine catabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" APLA010991-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" APLA005848-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA010315-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" APLA002501-PA 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" APLA003010-PA 13 MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Keratan sulfate degradation" APLA007494-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" APLA012591-PA 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" APLA014442-PA 13 Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;Reactome: R-HSA-202433;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;Reactome: R-HSA-9027277 "FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"Generation of second messenger molecules";"DAP12 signaling";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)" APLA004371-PA 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" APLA004087-PA 4 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" APLA001557-PA 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" APLA004820-PA 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" APLA000767-PA 3 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" APLA005995-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" APLA000227-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA012855-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" APLA001622-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" APLA008175-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA013146-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" APLA009726-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" APLA011311-PA 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" APLA002471-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA007623-PA 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" APLA009185-PA 14 Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158 "Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex" APLA012128-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" APLA008115-PA 13 Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-5140745 "LDL clearance";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" APLA014750-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA002169-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" APLA005798-PA 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" APLA000113-PA 7 Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" APLA009359-PA 1 Reactome: R-HSA-8876725 "Protein methylation" APLA001425-PA 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" APLA001062-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" APLA004459-PA 11 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-212436 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Generic Transcription Pathway" APLA003694-PA 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" APLA010330-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" APLA005697-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" APLA005382-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" APLA014671-PA 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" APLA004213-PA 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" APLA001199-PA 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" APLA013252-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" APLA006053-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" APLA004586-PA 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" APLA002072-PA 31 MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-5989;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-5366;Reactome: R-HSA-75105;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7746;MetaCyc: PWY-6282 "Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" APLA001255-PA 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" APLA007620-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" APLA003799-PA 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859 "Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly" APLA005723-PA 2 Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24 "MAPK6/MAPK4 signaling";"mTOR signaling pathway" APLA006355-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" APLA006728-PA 7 MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4 "Adenine and adenosine salvage V";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism" APLA012318-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA002642-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" APLA007157-PA 7 Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation" APLA013640-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" APLA014378-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" APLA007034-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" APLA008779-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" APLA004325-PA 11 MetaCyc: PWY-5659;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-882;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8 "GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism" APLA006943-PA 56 Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-68827 "Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Neddylation";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex" APLA005020-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" APLA012188-PA 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" APLA007133-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" APLA006016-PA 11 Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174430 "Activation of the pre-replicative complex";"DNA replication initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation" APLA002510-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" APLA002707-PA 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" APLA008707-PA 1 Reactome: R-HSA-8951664 "Neddylation" APLA010075-PA 4 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" APLA005762-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" APLA001825-PA 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" APLA001231-PA 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" APLA003532-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" APLA015199-PA 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" APLA001673-PA 9 KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25 "Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Sphingolipid metabolism";"Neutrophil degranulation";"Other glycan degradation" APLA000202-PA 8 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" APLA013588-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" APLA011286-PA 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" APLA009481-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" APLA008016-PA 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" APLA000768-PA 12 MetaCyc: PWY-6932;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25 "Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Sulfur metabolism";"Purine metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Purine metabolism" APLA005472-PA 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" APLA002304-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" APLA014015-PA 22 Reactome: R-HSA-5628897;MetaCyc: PWY-7347;MetaCyc: PWY-5054;KEGG: 00500+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-6981;MetaCyc: PWY-621;Reactome: R-HSA-6798695;MetaCyc: PWY-6142;MetaCyc: PWY-7238;MetaCyc: PWY-5514;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5384;MetaCyc: PWY-622;KEGG: 00030+5.3.1.9;KEGG: 00010+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-5659;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-8013 "TP53 Regulates Metabolic Genes";"Sucrose biosynthesis III";"D-sorbitol biosynthesis I";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Chitin biosynthesis";"Sucrose degradation III (sucrose invertase)";"Neutrophil degranulation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"UDP-N-acetyl-D-galactosamine biosynthesis III" APLA001232-PA 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" APLA000427-PA 33 Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-165054 "SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"HCMV Late Events";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA" APLA003250-PA 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6 "Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism" APLA012098-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" APLA007352-PA 1 Reactome: R-HSA-977347 "Serine biosynthesis" APLA014252-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" APLA012418-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108 "Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" APLA004137-PA 27 Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230 "NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA" APLA005084-PA 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" APLA000891-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" APLA008313-PA 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" APLA001948-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" APLA011663-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" APLA014003-PA 17 Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176408 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Neddylation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase" APLA012424-PA 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" APLA008489-PA 25 Reactome: R-HSA-8936459;Reactome: R-HSA-8939247;Reactome: R-HSA-9018519;Reactome: R-HSA-8951936;Reactome: R-HSA-8939243;Reactome: R-HSA-8941284;Reactome: R-HSA-8951911;Reactome: R-HSA-8939902;Reactome: R-HSA-8941326;Reactome: R-HSA-8941333;Reactome: R-HSA-8931987;Reactome: R-HSA-8878166;Reactome: R-HSA-8877330;Reactome: R-HSA-8939256;Reactome: R-HSA-8949275;Reactome: R-HSA-8939245;Reactome: R-HSA-8939236;Reactome: R-HSA-8939242;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8940973;Reactome: R-HSA-8935964;Reactome: R-HSA-8934593;Reactome: R-HSA-8941332;Reactome: R-HSA-8941858 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Estrogen-dependent gene expression";"RUNX3 regulates p14-ARF";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX2 expression and activity";"RUNX2 regulates bone development";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"Transcriptional regulation by RUNX2";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates expression of components of tight junctions";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX3 expression and activity" APLA009703-PA 30 Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-6796648 "RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes" APLA001189-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" APLA010497-PA 14 MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Methane metabolism" APLA014439-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" APLA000822-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" APLA000563-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" APLA001185-PA 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" APLA002857-PA 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation" APLA006986-PA 1 Reactome: R-HSA-156588 "Glucuronidation" APLA000204-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" APLA001417-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway"