Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_013195915.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013192899.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013192724.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_013196028.1 6 KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes" XP_013183954.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_013184082.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_013193340.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_013187783.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_013197809.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_013190910.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013199248.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_013193700.1 8 MetaCyc: PWY-7921;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis" XP_013201153.1 4 Reactome: R-HSA-8869496;Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Mitochondrial protein import" XP_013197403.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013183557.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176 "Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Neddylation";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_013200113.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_013198167.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_013183435.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013198916.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_013189965.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_013196635.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_013191692.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013190062.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_013185293.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013193364.1 5 KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)" XP_013199896.1 6 KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_013189701.1 3 Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807 "Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling" XP_013195159.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695 "MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation" XP_013192456.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013188852.1 29 Reactome: R-HSA-5693616;Reactome: R-HSA-6803207;Reactome: R-HSA-69541;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693565;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803204 "Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Stabilization of p53";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Thermogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_013199919.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_013192763.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis" XP_013191358.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_013191604.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_013201134.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_013186727.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013192962.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_013190992.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_013191936.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_013195757.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_013188222.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Macroautophagy" XP_013191815.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_013197053.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_013197714.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013189755.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_013200927.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_013194759.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_013187004.1 11 MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_013188611.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013199608.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_013193935.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013188429.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013185835.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_013187891.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_013192336.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_013188216.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_013186356.1 7 KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Pentose phosphate pathway";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_013187192.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6607;Reactome: R-HSA-8851680 "Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine catabolism";"Theophylline degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions" XP_013199628.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013192121.1 4 KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)" XP_013192782.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108 "PPARA activates gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_013197921.1 26 Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220 "MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Aggrephagy";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Cilium Assembly";"RHO GTPases Activate Formins" XP_013187501.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_013201025.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_013191928.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_013197346.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_013187329.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol" XP_013184033.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_013187814.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013192825.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_013193875.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013184715.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_013193527.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_013189819.1 17 Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-1169091;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-4086398 "TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ca2+ pathway" XP_013194057.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_013187258.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013191822.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013195908.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013189977.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013185558.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_013188185.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013193768.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_013195721.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_013195116.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013183529.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013194215.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_013192810.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_013185704.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-983231 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production" XP_013186018.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013189746.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_013198536.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013198378.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013200332.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013191372.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013183531.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013184990.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_013196087.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_013200447.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013196693.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_013185792.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_013186229.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_013185894.1 14 KEGG: 00280+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5104;MetaCyc: PWY-5103;MetaCyc: PWY-5057;MetaCyc: PWY-7767;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism" XP_013187171.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013191228.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_013183506.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_013184874.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_013183622.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013185759.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_013192762.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013186309.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_013186313.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_013188976.1 6 Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway" XP_013200273.1 6 MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism" XP_013199884.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_013187384.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_013190991.1 19 Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497 "Clathrin-mediated endocytosis";"Chylomicron clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Scavenging by Class A Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"VLDL clearance";"VLDL assembly";"Scavenging by Class B Receptors";"Chylomicron remodeling";"LDL clearance";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors" XP_013188540.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_013198433.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_013183853.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013185231.1 17 MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_013195613.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_013191778.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013184928.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013183492.1 15 Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_013183535.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013194576.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_013201209.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013187394.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013200044.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013189652.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_013183769.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_013182988.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_013191902.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013196810.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013196471.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013197631.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_013196927.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013197671.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_013194485.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013200975.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_013197994.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_013195912.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013184352.1 3 MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_013198303.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_013186423.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_013184547.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969 "Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina" XP_013184973.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013187266.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_013192168.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" XP_013189700.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013197910.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_013195277.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013191931.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_013193207.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_013184193.1 9 Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" XP_013191967.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013199814.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_013183412.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400 "VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_013190087.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907 "RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_013193235.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_013184046.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_013194240.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_013198773.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013190760.1 17 Reactome: R-HSA-74217;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-4202 "Purine salvage";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)" XP_013187331.1 4 MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483 "Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)" XP_013199809.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-9630221;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1" XP_013196743.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013188532.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013197565.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_013187629.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013193659.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_013186184.1 6 Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_013190460.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_013188829.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_013200213.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_013196103.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013197534.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_013197226.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules" XP_013200752.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013194300.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_013196504.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_013192293.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_013194297.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013199423.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013190900.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_013191884.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013188314.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013189426.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013197967.1 56 Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050 "APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_013186988.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013199417.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557 "Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis" XP_013190061.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_013189512.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013195030.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_013184339.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_013190553.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013192110.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013196100.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_013201235.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013187169.1 3 MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987 "Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis" XP_013199164.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013184782.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013198390.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013185489.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_013200422.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013183977.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_013188921.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_013183357.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_013192329.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013191827.1 17 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_013192760.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013199215.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_013197021.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_013196006.1 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol" XP_013187278.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013194210.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_013195007.1 9 Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-8856825 "Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Cargo recognition for clathrin-mediated endocytosis" XP_013182986.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_013193281.1 12 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013191834.1 10 MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose metabolism";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_013195669.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_013198368.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_013190128.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_013189587.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013194737.1 5 Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus" XP_013185140.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_013199322.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_013184028.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292 "Neutrophil degranulation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome" XP_013191317.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_013190881.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013190012.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013190218.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_013188560.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_013183864.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013192533.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_013195854.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013188371.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_013198333.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_013191916.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013192415.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013187400.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_013185273.1 4 Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_013195635.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_013192109.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013185363.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_013183385.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_013188903.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013189484.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_013183986.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013194189.1 5 Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381 "Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_013188411.1 31 MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-7664;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-6799;MetaCyc: PWY-6282;MetaCyc: PWY-5142;MetaCyc: PWY-8012;Reactome: R-HSA-199220;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWY-5147 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mupirocin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)" XP_013190753.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013185680.1 7 MetaCyc: PWY-5695;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-6596 "Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I" XP_013191431.1 4 KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.9 "Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_013196578.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013198022.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_013186562.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_013183679.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_013200971.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_013198592.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013195864.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_013184925.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_013189769.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013197861.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER" XP_013194233.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_013184817.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-3781 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)" XP_013200453.1 3 KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3 "Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism" XP_013184374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013185751.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013183796.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013195972.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-72163;MetaCyc: PWY-7511;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Protein ubiquitination";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_013189157.1 13 Reactome: R-HSA-2029485;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052 "Role of phospholipids in phagocytosis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis" XP_013196118.1 20 MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7858 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II" XP_013192649.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane" XP_013188741.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_013192903.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_013183647.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013194660.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_013198176.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013193554.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis" XP_013199409.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_013191875.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_013200359.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_013192303.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_013185710.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662 "TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism" XP_013199362.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013191348.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013192650.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-9013973 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7" XP_013199813.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_013196802.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013185937.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_013196975.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013192738.1 33 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-9610379 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"snRNP Assembly";"HCMV Late Events" XP_013189340.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013187633.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043 "G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events" XP_013190987.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6 "Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism" XP_013187310.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_013186508.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-68952 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"DNA replication initiation" XP_013200604.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013191934.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013184528.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013185443.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013198099.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_013192077.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013184052.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_013183236.1 6 KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_013184795.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_013187343.1 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" XP_013187029.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013199634.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013183768.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_013186085.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013196523.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits" XP_013182857.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_013198757.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_013198777.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_013191021.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_013191179.1 40 Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-167287 "Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"HIV elongation arrest and recovery" XP_013184113.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52 "Keratan sulfate degradation";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_013184866.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_013195114.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_013194612.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_013195081.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013197221.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_013183737.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_013200017.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_013190993.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_013187509.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013192574.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_013188290.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_013188677.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_013190159.1 7 Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-373080 "Hedgehog ligand biogenesis";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)" XP_013187049.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-110329;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-427359;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-2559580;Reactome: R-HSA-606279;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-2559586;Reactome: R-HSA-5250924;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9610379;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-73772 "Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"Amyloid fiber formation";"HCMV Early Events";"Cleavage of the damaged pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"SIRT1 negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"Oxidative Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"DNA Damage/Telomere Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"HCMV Late Events";"Meiotic synapsis";"HDACs deacetylate histones";"HDMs demethylate histones";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape" XP_013184933.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_013194034.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013199730.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013186058.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013196008.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_013185559.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013192135.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013185376.1 7 MetaCyc: PWY-7282;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" XP_013195140.1 7 MetaCyc: PWY-6605;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;Reactome: R-HSA-74217;MetaCyc: PWY-7805;MetaCyc: PWY-6610 "Adenine and adenosine salvage II";"Neutrophil degranulation";"Purine metabolism";"Glyphosate degradation III";"Purine salvage";"(aminomethyl)phosphonate degradation";"Adenine salvage" XP_013183612.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_013189444.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_013194472.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_013199443.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013185098.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_013187839.1 7 Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;MetaCyc: PWY-5265 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)" XP_013188356.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_013183875.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360 "Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_013185582.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013189551.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013197545.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013196300.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013187285.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_013187877.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013197013.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_013187304.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_013190123.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013199403.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_013197559.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013197272.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_013188902.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013199891.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_013192537.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_013184118.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_013197014.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_013183068.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013185793.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_013184233.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013191412.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013184473.1 26 Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-8866654;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-69205;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6804114;Reactome: R-HSA-5696397 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"E3 ubiquitin ligases ubiquitinate target proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G1/S-Specific Transcription";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_013189112.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013192648.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_013193157.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013189414.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" XP_013184815.1 1 Reactome: R-HSA-3000171 "Non-integrin membrane-ECM interactions" XP_013189197.1 10 MetaCyc: PWY-5484;KEGG: 00562+5.3.1.1;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Glycolysis II (from fructose 6-phosphate)";"Inositol phosphate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Glycolysis" XP_013183359.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013193201.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_013183925.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013185561.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013192858.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013191757.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_013184962.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_013192744.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013197625.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_013197816.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013199745.1 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-7219;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2 "Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_013191890.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013188607.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013192950.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013200339.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_013190843.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013189609.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_013197721.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013195168.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_013192304.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_013192609.1 34 Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-9639288;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813 "NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Amino acids regulate mTORC1";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Separation of Sister Chromatids" XP_013191779.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013187555.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013198544.1 16 Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-201722 "DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Formation of the beta-catenin:TCF transactivating complex" XP_013188354.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_013183816.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013189997.1 4 MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50 "Spermidine biosynthesis III";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_013197508.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_013192516.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_013191714.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128 "Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"Neddylation";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling" XP_013195365.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_013194714.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_013185406.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_013183600.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013189574.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013184211.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_013187367.1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-190861 "Aggrephagy";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly" XP_013189750.1 20 KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Human papillomavirus infection";"Amino acids regulate mTORC1";"mTOR signalling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Macroautophagy";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway" XP_013196117.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013186566.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013199495.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_013193819.1 19 Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;Reactome: R-HSA-163765 "Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression" XP_013188110.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013183428.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8051 "Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I" XP_013197268.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" XP_013185748.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013182875.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013198511.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_013185590.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_013191430.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_013185978.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013200666.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_013196112.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_013200309.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013183561.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013190162.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends" XP_013187661.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_013183541.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013183843.1 22 MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134 "Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation" XP_013200558.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013191965.1 13 Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_013195504.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013187807.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase" XP_013194305.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013184823.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013193242.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_013182965.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_013186040.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013197806.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_013200649.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_013191487.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013194031.1 8 KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-7734;MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733 "Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis" XP_013193396.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_013199225.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013187664.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_013185640.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013196203.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013186167.1 6 MetaCyc: PWY-6608;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606;Reactome: R-HSA-74259 "Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine catabolism" XP_013188848.1 7 Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_013195113.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_013195756.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013191923.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013193952.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013195867.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_013187773.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_013199367.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013185707.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_013186996.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_013187909.1 6 MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" XP_013186633.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_013200910.1 4 KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2 "Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_013187632.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043 "G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events" XP_013191792.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_013198517.1 1 Reactome: R-HSA-5578775 "Ion homeostasis" XP_013196232.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_013200638.1 17 Reactome: R-HSA-2559580;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-8953750;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-9616222;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-69656;Reactome: R-HSA-111448 "Oxidative Stress Induced Senescence";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Transcriptional Regulation by E2F6";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Transcriptional regulation of granulopoiesis";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria" XP_013199236.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism" XP_013194853.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_013193599.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013186258.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_013200259.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_013196353.1 3 MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17 "Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism" XP_013187911.1 6 MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709 "Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins" XP_013193295.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013184320.1 5 KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;Reactome: R-HSA-532668 "N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_013184898.1 19 Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-428543 "RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1" XP_013189657.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013192284.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_013186936.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_013192963.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_013188000.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis" XP_013191027.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013193913.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469 "Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis" XP_013197547.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes" XP_013193949.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis" XP_013191574.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_013184116.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_013184464.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_013199113.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013194884.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013190551.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" XP_013193523.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_013183214.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013193651.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation" XP_013188329.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_013200594.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013188978.1 6 Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_013190409.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_013197483.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_013188284.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_013200555.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013188218.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_013195935.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_013183831.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013195382.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_013185708.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_013200730.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013184239.1 19 KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622 "Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)" XP_013195764.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013191636.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013184951.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_013183396.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_013184635.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_013198243.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_013189325.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_013183416.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013197117.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_013184307.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_013184778.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_013187874.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013183017.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_013188832.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_013186094.1 9 Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932 "Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules" XP_013191341.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013194492.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013195257.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_013197725.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_013196740.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180534 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"UCH proteinases";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4" XP_013186950.1 26 Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids" XP_013183390.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013201152.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013194134.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013196750.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_013194863.1 3 KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism" XP_013184475.1 4 MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_013182930.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789 "Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Iron uptake and transport";"Neddylation";"TGF-beta receptor signaling activates SMADs" XP_013196204.1 18 MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Arginine and proline metabolism";"Arginine biosynthesis" XP_013183423.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013190806.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013191232.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_013197381.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_013186253.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_013197188.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013196606.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013197987.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_013184831.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_013200350.1 7 MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism" XP_013197634.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_013186565.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013195861.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_013190511.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_013200264.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013184508.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_013188149.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013187033.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"B-WICH complex positively regulates rRNA expression" XP_013188696.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_013198510.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_013188254.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_013198789.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_013194728.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013197449.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013188708.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_013190004.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141 "Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism" XP_013188874.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013186107.1 12 KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1 "Pyruvate metabolism";"Propanoate metabolism";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes" XP_013201160.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013200623.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013189343.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013196670.1 13 KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-7384;KEGG: 00620+4.2.1.2 "Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate metabolism" XP_013200846.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_013197459.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013183344.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013195878.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_013200729.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_013188828.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_013190100.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013196859.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_013186842.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013200168.1 5 KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_013193618.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_013195628.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6798695;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex" XP_013194717.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013193521.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_013194195.1 7 Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_013200140.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_013183845.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_013188127.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013183356.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_013185632.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409 "APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_013186771.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_013185785.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_013193767.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_013188658.1 5 KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation" XP_013186196.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_013188818.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013185763.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_013188102.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15 "Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_013195844.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_013184190.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_013197442.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_013196183.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_013185890.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis" XP_013187160.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013191169.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013196860.1 31 MetaCyc: PWY-5989;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-5367;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-5971;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWY-6282 "Stearate biosynthesis II (bacteria and plants)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" XP_013185154.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013185457.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013192407.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex" XP_013194364.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Photosynthesis" XP_013200988.1 8 Reactome: R-HSA-373080;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-4608870;Reactome: R-HSA-5099900;Reactome: R-HSA-4641263;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398 "Class B/2 (Secretin family receptors)";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Asymmetric localization of PCP proteins";"WNT5A-dependent internalization of FZD4";"Regulation of FZD by ubiquitination";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway" XP_013198308.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013187552.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013187725.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling" XP_013183735.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_013189381.1 5 KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II" XP_013190757.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68949 "CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin" XP_013198371.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013189098.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013185145.1 29 Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER" XP_013183689.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471 "Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_013195102.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_013192551.1 4 Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656 "MET activates RAP1 and RAC1";"Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling" XP_013197040.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_013185866.1 6 KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_013184910.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_013192942.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_013194878.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_013186198.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_013190280.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_013201256.1 9 KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5 "Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine catabolism";"Novobiocin biosynthesis";"Cysteine and methionine metabolism" XP_013194507.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013188911.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013192944.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013192439.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_013196076.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013183626.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_013185996.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_013196524.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis" XP_013189585.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_013185685.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_013187420.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013191801.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7838;MetaCyc: PWY-7836 "Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis" XP_013187214.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013184862.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" XP_013183243.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_013188441.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_013191233.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_013193302.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_013186976.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_013197166.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_013197723.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013191034.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013191765.1 5 KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32 "Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)" XP_013191863.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_013182978.1 27 Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-159236;Reactome: R-HSA-72203;Reactome: R-HSA-159227;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-159231;Reactome: R-HSA-674695;Reactome: R-HSA-73856;Reactome: R-HSA-167152;Reactome: R-HSA-111367;Reactome: R-HSA-167242;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-77595;Reactome: R-HSA-113418;Reactome: R-HSA-77588;Reactome: R-HSA-975957;Reactome: R-HSA-6803529;Reactome: R-HSA-159230;Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of the SLBP independent Mature mRNA";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"SLBP independent Processing of Histone Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"Formation of the Early Elongation Complex";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"Transport of the SLBP Dependant Mature mRNA";"RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_013188979.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_013183431.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_013190510.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013191751.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_013191390.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_013196319.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_013199209.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013189994.1 2 Reactome: R-HSA-392154;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes" XP_013187287.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_013200285.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_013189433.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6433 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_013194741.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_013183011.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_013192620.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828 "Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"LDL clearance";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Scavenging by Class A Receptors";"Chylomicron clearance";"Clathrin-mediated endocytosis" XP_013186938.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_013193955.1 11 MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7456 "Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation" XP_013193110.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013195394.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5981 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III" XP_013192290.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_013190035.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_013198817.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013200116.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_013187409.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_013196774.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_013189754.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013193413.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013186843.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_013200575.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_013189173.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_013199853.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013199609.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013189253.1 40 KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6946;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7656;MetaCyc: PWY-6863;MetaCyc: PWY-6583;MetaCyc: PWY-7094;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7401 "Fatty acid elongation";"Geraniol degradation";"Fatty acid degradation";"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism";"beta-Alanine metabolism";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Lysine degradation";"Phenylalanine metabolism";"Benzoyl-coa degradation I (aerobic)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"Fatty acid salvage";"Caprolactam degradation";"2-methylpropene degradation";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Limonene and pinene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)" XP_013188901.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_013190849.1 13 MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-6370 "Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Ascorbate recycling (cytosolic)" XP_013188739.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_013196703.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_013200162.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013196643.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_013183399.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013190189.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013190543.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_013189936.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013190236.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_013196027.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" XP_013192327.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" XP_013192380.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013192047.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013195964.1 9 Reactome: R-HSA-198323;Reactome: R-HSA-168638;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-5674400;Reactome: R-HSA-418889 "AKT phosphorylates targets in the cytosol";"NOD1/2 Signaling Pathway";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"Caspase activation via Dependence Receptors in the absence of ligand" XP_013197213.1 12 Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408 "RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation" XP_013191870.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_013195763.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_013195594.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_013193939.1 17 MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086 "Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_013200974.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_013190922.1 15 Reactome: R-HSA-3214847;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "HATs acetylate histones";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_013195652.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013184872.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_013190801.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013198605.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013191643.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013188231.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013189986.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_013187395.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013195517.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_013192105.1 8 KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1 "Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism" XP_013187882.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013192219.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_013184494.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_013183294.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013186783.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" XP_013191677.1 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3 "Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism" XP_013194156.1 7 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034 "Ligand-receptor interactions";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np" XP_013186451.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013193048.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013191438.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_013190704.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013200967.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_013191679.1 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043 "Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis" XP_013200380.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_013195217.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013197126.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_013186733.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013187779.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_013183331.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013190475.1 1 Reactome: R-HSA-419771 "Opsins" XP_013189472.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_013187037.1 3 Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Amyloid fiber formation";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_013189082.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013183376.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_013199445.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_013197480.1 3 KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_013184988.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_013195838.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013191674.1 10 MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;MetaCyc: PWY-7661;MetaCyc: PWY-7979;Reactome: R-HSA-4717374 "Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)" XP_013193167.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_013190661.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_013195426.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453 "Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis" XP_013197414.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_013191401.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168276 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"HCMV Late Events";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways" XP_013185869.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013184954.1 7 KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;MetaCyc: PWY-6134 "Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylketonuria";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV" XP_013200466.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_013191395.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_013189618.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013194273.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_013183384.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_013184014.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013184416.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013199388.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013195644.1 57 Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813 "APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids" XP_013195963.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_013200366.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_013187838.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013195370.1 7 MetaCyc: PWY-4984;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31 "Urea cycle";"Putrescine biosynthesis III";"Arginine and proline metabolism";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Canavanine degradation" XP_013189770.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013198313.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013198795.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion" XP_013198469.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_013199623.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_013197610.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756 "Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation" XP_013196042.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_013199561.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_013198699.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_013187746.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_013183314.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"snRNP Assembly";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus" XP_013196916.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_013194642.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_013191837.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_013182999.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_013192371.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_013185061.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013199815.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_013187875.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013195865.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013187899.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013194480.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_013193380.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013200175.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013187551.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013200719.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_013197115.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_013195495.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_013193356.1 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol" XP_013199685.1 16 Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569 "Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_013195520.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_013189744.1 20 Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04150+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Human papillomavirus infection";"HSF1-dependent transactivation";"mTOR signaling pathway" XP_013195255.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_013188849.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013196136.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_013200246.1 15 MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7383 "Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycerol degradation to butanol";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_013193567.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins" XP_013197927.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_013185622.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013192611.1 6 MetaCyc: PWY-6580;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367 "Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_013191793.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_013186272.1 13 MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6969 "Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_013193370.1 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" XP_013184549.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-1236974 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway" XP_013194010.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP" XP_013187356.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4 "Anandamide biosynthesis I";"Plasmalogen degradation";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_013192216.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_013190869.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_013183183.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_013200611.1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902 "Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Degradation of DVL";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity" XP_013198329.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013183683.1 5 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_013185105.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013199405.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_013191351.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_013195752.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013195893.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_013188358.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_013183562.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013192804.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_013189548.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013184192.1 9 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-9656255 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"Defective OGG1 Substrate Binding" XP_013195471.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_013194875.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013195314.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453 "Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis" XP_013183392.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013199260.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013190312.1 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_013191230.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_013185845.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_013199803.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_013190331.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_013195717.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_013185936.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_013200571.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_013199108.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013189440.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_013187490.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68827 "G1/S-Specific Transcription";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex" XP_013199794.1 17 Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"mTOR signaling pathway" XP_013190283.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_013197996.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013196964.1 10 MetaCyc: PWY-922;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10 "Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Terpenoid backbone biosynthesis" XP_013189637.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013194933.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_013199923.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_013190542.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_013186614.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_013196148.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_013183534.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_013193633.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" XP_013197736.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013197426.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation" XP_013192984.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_013192601.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I" XP_013193498.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-606279 "Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_013190591.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_013190951.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_013200949.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013189170.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013199115.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013184584.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_013200831.1 10 MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-5497 "L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)" XP_013198707.1 18 MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00401+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Arginine biosynthesis";"Phenylalanine metabolism";"Novobiocin biosynthesis" XP_013194578.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_013185625.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013189275.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013187162.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_013200909.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_013192832.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013200687.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013184325.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism" XP_013183014.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013183653.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852 "Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy" XP_013191784.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013190478.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_013185944.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_013183558.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_013184827.1 11 Reactome: R-HSA-191273;MetaCyc: PWY-7560;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6383;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7524;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I" XP_013191231.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_013193369.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_013193379.1 3 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism" XP_013188035.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_013198631.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_013194306.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013185981.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013192978.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_013195596.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013190544.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_013183554.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013184428.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)" XP_013196288.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013200653.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013184146.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-195253 "AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex" XP_013190275.1 9 MetaCyc: PWY-5981;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-5667 "CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I" XP_013194738.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-5205685 "Interleukin-1 signaling";"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy" XP_013187030.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013191382.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013195017.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_013200048.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013187562.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013191709.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013185122.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5632987 "Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2" XP_013197196.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_013200495.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013185474.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_013193233.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_013193265.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013192473.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_013201111.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_013185687.1 10 Reactome: R-HSA-380320;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5696394;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"DNA Damage Recognition in GG-NER";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_013196068.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013191384.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013187027.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013192751.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013189675.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013182898.1 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" XP_013186247.1 3 KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism" XP_013194455.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_013196417.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013187116.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_013194687.1 14 Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;MetaCyc: PWY-6453 "Synthesis of PE";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PC";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Stigma estolide biosynthesis" XP_013186696.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_013197233.1 7 Reactome: R-HSA-203641;Reactome: R-HSA-3928662;Reactome: R-HSA-373753;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-418885 "NOSTRIN mediated eNOS trafficking";"EPHB-mediated forward signaling";"Nephrin family interactions";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"DCC mediated attractive signaling" XP_013185823.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_013199119.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091 "G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching" XP_013186230.1 4 KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_013196088.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_013191532.1 1 Reactome: R-HSA-156581 "Methylation" XP_013201243.1 32 Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-72163 "Estrogen-dependent gene expression";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway" XP_013194754.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013200883.1 6 Reactome: R-HSA-446199;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;Reactome: R-HSA-2426168 "Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_013184891.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354 "AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy" XP_013192741.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_013186738.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013195161.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_013185360.1 6 Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism" XP_013194684.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035 "TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_013191956.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_013191836.1 10 MetaCyc: PWY-6397;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"D-galactose detoxification";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_013192044.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013193604.1 9 KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00510+2.4.1.141;Reactome: R-HSA-5633231 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_013197174.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013188351.1 12 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2467813;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5663220 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Th1 and Th2 cell differentiation";"Separation of Sister Chromatids";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RHO GTPases Activate Formins" XP_013186896.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_013198805.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013201094.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_013192583.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_013196679.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013193030.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_013185865.1 6 Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_013187086.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_013191915.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013189118.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013184569.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_013195612.1 7 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_013185733.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_013192563.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802955 "MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_013199585.1 5 KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;MetaCyc: PWY-5269;MetaCyc: PWY-7817;Reactome: R-HSA-1483148 "Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG" XP_013192049.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013191783.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013197549.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013193566.1 24 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Recycling pathway of L1";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation" XP_013194270.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_013190263.1 4 KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II" XP_013191781.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_013184044.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217 "Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage" XP_013193215.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013187670.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013197030.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_013199734.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013183166.1 11 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_013189510.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013194601.1 12 MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-6978 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II" XP_013191605.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_013196669.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_013199039.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_013188073.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_013192096.1 8 KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis" XP_013199228.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_013187379.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events" XP_013186334.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_013192065.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013193109.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013185100.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_013182852.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-159227 "Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Late Events";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA" XP_013185926.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_013190710.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013192575.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_013187157.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013192996.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_013188827.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013191707.1 16 Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167290 "Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation" XP_013185421.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013184511.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013186050.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013200286.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_013191882.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_013189848.1 3 KEGG: 00520+5.4.2.10;KEGG: 00970+6.3.5.7;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"Aminoacyl-tRNA biosynthesis";"CMP-legionaminate biosynthesis I" XP_013188359.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_013184480.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013199805.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_013189389.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_013192043.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013195919.1 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" XP_013192550.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8875656 "Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"MET receptor recycling" XP_013189732.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_013185417.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_013188654.1 20 MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7288;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-6837 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_013184492.1 5 Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_013187313.1 13 MetaCyc: PWY-7198;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Glutathione metabolism" XP_013200238.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_013189549.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013193802.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_013189159.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_013200697.1 3 Reactome: R-HSA-4086400;Reactome: R-HSA-373080;Reactome: R-HSA-4608870 "PCP/CE pathway";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins" XP_013185032.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013182945.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013183636.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013201214.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_013189266.1 40 KEGG: 00627+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7656;MetaCyc: PWY-6863;MetaCyc: PWY-6583;MetaCyc: PWY-7094;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-5136;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00410+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6946;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-7606 "Aminobenzoate degradation";"Lysine degradation";"Phenylalanine metabolism";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"Fatty acid salvage";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"2-methylpropene degradation";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Limonene and pinene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid elongation";"Fatty acid degradation";"Geraniol degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"beta-Alanine metabolism";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_013191506.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_013184798.1 14 KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-1042 "Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)" XP_013183774.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_013192662.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_013197484.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_013199402.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Ion channel transport";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1" XP_013199808.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_013189659.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_013199883.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_013193132.1 7 MetaCyc: PWY-8043;MetaCyc: PWY-6840;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2 "Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_013200011.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013198672.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_013194575.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_013195392.1 14 MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7589 "Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)" XP_013188785.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-5981;MetaCyc: PWY-8055 "Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis" XP_013196441.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_013186531.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-447043;Reactome: R-HSA-3928664 "Neutrophil degranulation";"Neurofascin interactions";"Ephrin signaling" XP_013190000.1 5 Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes" XP_013189806.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013194740.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209543 "Interleukin-1 signaling";"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes" XP_013183617.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013200361.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_013194298.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_013191278.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013188141.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_013186815.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013190065.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983 "ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)" XP_013192906.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013196879.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013199126.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013200033.1 3 MetaCyc: PWY-1269;Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism";"Lipopolysaccharide biosynthesis" XP_013182972.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_013194191.1 5 Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695 "Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation" XP_013196632.1 3 MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450 "Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion" XP_013182888.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013200972.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_013183937.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_013198251.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_013193483.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013197960.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013186465.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_013194932.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013197954.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_013186946.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289 "Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation" XP_013199166.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013187112.1 4 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_013199418.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013197911.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013189421.1 7 Reactome: R-HSA-5689880;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "Ub-specific processing proteases";"DNA Damage Recognition in GG-NER";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Telomere Extension By Telomerase" XP_013197635.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_013193526.1 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_013199103.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_013197715.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013199925.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_013200693.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013187360.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013198086.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013185191.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_013197368.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_013188323.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_013185491.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013194303.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013183018.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_013190628.1 29 Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-112382 "RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex" XP_013185058.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_013185803.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_013184404.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)" XP_013195880.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_013195621.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_013187293.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_013200540.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_013189816.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_013196794.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013185638.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013192285.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_013199017.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013198485.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_013186632.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_013194994.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013199490.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013197051.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_013186977.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013184777.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013191708.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-167243 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery" XP_013185486.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_013187724.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-381676 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_013187718.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_013199687.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013191162.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013184043.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_013185097.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_013191010.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_013187916.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_013183714.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013196023.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_013194096.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4061 "Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I" XP_013186264.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013197276.1 5 MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514 "Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_013183758.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013188891.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013200917.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_013193438.1 17 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7222 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_013198504.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013199990.1 15 Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-69473 "DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint" XP_013189437.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_013184998.1 13 MetaCyc: PWY-6969;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-8086;MetaCyc: PWY-5392 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II" XP_013199723.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_013187585.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_013188309.1 6 MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484 "Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)" XP_013195754.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013185931.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013191911.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_013199785.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013191079.1 6 MetaCyc: PWY-7238;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737 "Sucrose biosynthesis II";"Starch degradation III";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V" XP_013195434.1 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_013187660.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013187385.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_013182918.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69481 "ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints" XP_013194874.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_013194997.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_013197207.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013188892.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_013199854.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013192140.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013191616.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3000178 "Protein ubiquitination";"ECM proteoglycans" XP_013191256.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_013193381.1 52 Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-749476;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-1834949;Reactome: R-HSA-6781827;Reactome: R-HSA-76061;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-77075 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"FGFR2 alternative splicing";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Cytosolic sensors of pathogen-associated DNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE" XP_013185908.1 8 KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-163754;MetaCyc: PWY-5723;Reactome: R-HSA-6791055 "Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" XP_013183762.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_013190273.1 9 Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8 "Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_013199063.1 5 KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033500 "Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins" XP_013186885.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" XP_013190027.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013191951.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751 "Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity" XP_013197604.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013199330.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013191236.1 10 MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484 "1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)" XP_013201194.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_013194879.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_013198958.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013184016.1 31 MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-6282;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;MetaCyc: PWY-5971;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-8049 "Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Superpathway of mycolate biosynthesis";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Pederin biosynthesis" XP_013190380.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013200970.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_013185646.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_013187601.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint" XP_013191306.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_013184012.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013197027.1 5 KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532 "Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)" XP_013198488.1 11 Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_013185356.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_013200689.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I" XP_013195689.1 10 Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint" XP_013187142.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells" XP_013200563.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013189196.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013196641.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_013199254.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013186958.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013185817.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013185684.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_013192138.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013193293.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013187829.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_013182975.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_013187386.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_013187006.1 18 Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-72086 "TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"mRNA Capping" XP_013192637.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_013199303.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_013192956.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013200114.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_013186807.1 17 Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-1834949;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-3270619 "Meiotic recombination";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Cytosolic sensors of pathogen-associated DNA";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"IRF3-mediated induction of type I IFN" XP_013190945.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_013200759.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013186516.1 4 MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol" XP_013189388.1 5 KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II" XP_013185459.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013188672.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013197178.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_013186488.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_013189586.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013192129.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_013192002.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013184839.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_013191246.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013188727.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013200743.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_013190968.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_013194253.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_013200664.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013198481.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013200225.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_013200875.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport" XP_013194465.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_013185580.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_013189826.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Macroautophagy" XP_013193654.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_013186426.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_013191681.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013200156.1 17 KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-8086;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622 "Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)" XP_013190367.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_013185380.1 7 MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-7282 "5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_013190284.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_013193368.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_013188247.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_013199871.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013194190.1 5 Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695 "Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation" XP_013189501.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_013196654.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_013187066.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_013196142.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332 "Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_013184633.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_013191062.1 12 KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9 "Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Sucrose biosynthesis II";"Galactose metabolism";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism" XP_013186740.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013199560.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_013198555.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_013188428.1 11 Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-170660 "G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Adenylate cyclase activating pathway" XP_013185303.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_013188002.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445 "Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation" XP_013186835.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_013198090.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_013193495.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_013195706.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013190840.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013192592.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_013193182.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_013193907.1 27 KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-399956;Reactome: R-HSA-5358747;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-3371453;Reactome: R-HSA-5358749;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-5339716;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-195253;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5250924;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-5358751;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5610785 "mTOR signaling pathway";"Truncations of AMER1 destabilize the destruction complex";"CRMPs in Sema3A signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"AXIN missense mutants destabilize the destruction complex";"Regulation of HSF1-mediated heat shock response";"S37 mutants of beta-catenin aren't phosphorylated";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"Misspliced GSK3beta mutants stabilize beta-catenin";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Degradation of beta-catenin by the destruction complex";"PI3K-Akt signaling pathway";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"B-WICH complex positively regulates rRNA expression";"Thermogenesis";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"S45 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"GLI3 is processed to GLI3R by the proteasome" XP_013196480.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_013194059.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_013191762.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_013183697.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_013194333.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_013193471.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013199559.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_013190149.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_013183939.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_013191772.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_013193512.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013183671.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_013196212.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_013185136.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_013184734.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_013183673.1 12 Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-75893 "Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"TNF signaling" XP_013198685.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013192452.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013195339.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_013197385.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013193346.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_013195145.1 44 Reactome: R-HSA-112409;Reactome: R-HSA-6802948;Reactome: R-HSA-1295596;Reactome: R-HSA-456926;Reactome: R-HSA-74749;Reactome: R-HSA-5654726;Reactome: R-HSA-450341;Reactome: R-HSA-8939211;Reactome: R-HSA-5663213;Reactome: R-HSA-198753;Reactome: R-HSA-2559582;Reactome: R-HSA-2559580;Reactome: R-HSA-5674499;Reactome: R-HSA-6802952;Reactome: R-HSA-9634638;Reactome: R-HSA-5668599;Reactome: R-HSA-8943724;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-162658;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-9635465;Reactome: R-HSA-170968;Reactome: R-HSA-881907;Reactome: R-HSA-5654727;Reactome: R-HSA-9627069;Reactome: R-HSA-2029482;Reactome: R-HSA-375165;Reactome: R-HSA-5674135;Reactome: R-HSA-6811558;Reactome: R-HSA-8940973;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-2559585;Reactome: R-HSA-5654733;Reactome: R-HSA-6802955;Reactome: R-HSA-982772;Reactome: R-HSA-2871796;Reactome: R-HSA-6802946;Reactome: R-HSA-5654732;Reactome: R-HSA-445144;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24 "RAF-independent MAPK1/3 activation";"Signaling by high-kinase activity BRAF mutants";"Spry regulation of FGF signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Signal attenuation";"Negative regulation of FGFR1 signaling";"Activation of the AP-1 family of transcription factors";"ESR-mediated signaling";"RHO GTPases Activate WASPs and WAVEs";"ERK/MAPK targets";"Senescence-Associated Secretory Phenotype (SASP)";"Oxidative Stress Induced Senescence";"Negative feedback regulation of MAPK pathway";"Signaling by BRAF and RAF fusions";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate NADPH Oxidases";"Regulation of PTEN gene transcription";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"RSK activation";"ERKs are inactivated";"Suppression of apoptosis";"Frs2-mediated activation";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR2 signaling";"Regulation of the apoptosome activity";"Regulation of actin dynamics for phagocytic cup formation";"NCAM signaling for neurite out-growth";"MAP2K and MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RUNX2 regulates osteoblast differentiation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Oncogene Induced Senescence";"Negative regulation of FGFR4 signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Growth hormone receptor signaling";"FCERI mediated MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR3 signaling";"Signal transduction by L1";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway" XP_013192184.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_013200878.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013188436.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013188360.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_013199229.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013194069.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_013201257.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013200239.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_013194119.1 11 KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-5675 "Arginine biosynthesis";"Ammonia assimilation cycle I";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)" XP_013183362.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_013189175.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_013190689.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013189589.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013193879.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_013190671.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_013184479.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013192538.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_013200669.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013186877.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2 "4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism" XP_013196262.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013200586.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013190106.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_013196929.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_013200660.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_013196646.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_013201289.1 18 KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"Phenylalanine metabolism";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_013186075.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013185608.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013197347.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_013186847.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_013196567.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013191533.1 1 Reactome: R-HSA-156581 "Methylation" XP_013186653.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_013198885.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_013188813.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167200 "Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_013188614.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_013196880.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" XP_013192174.1 15 Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_013185663.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013190303.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-434316 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_013195673.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_013192004.1 25 Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "Gap junction assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Cilium Assembly";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_013191635.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013194964.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013191030.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013186101.1 29 Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-76042 "Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"mRNA Capping";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_013200870.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571 "IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)" XP_013193249.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013184524.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_013192793.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_013193886.1 9 KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013192492.1 9 KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1 "Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" XP_013197537.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013190615.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013201055.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_013196921.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_013200450.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013186103.1 17 KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9022692;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-174178;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-141444;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Human papillomavirus infection";"Regulation of MECP2 expression and activity";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Human cytomegalovirus infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human immunodeficiency virus 1 infection";"EML4 and NUDC in mitotic spindle formation";"Thermogenesis";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Relaxin signaling pathway" XP_013187883.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013185472.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_013186759.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_013184321.1 10 Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5607761 "Downstream TCR signaling";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_013187831.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_013191134.1 14 Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-165054 "Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA" XP_013185228.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013190188.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_013192957.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013198221.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_013187088.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013188097.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_013186990.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013197662.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" XP_013187221.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_013183441.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013198804.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013197826.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_013200747.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013185772.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response" XP_013200489.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_013200244.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171 "Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_013199442.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013186293.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_013186926.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" XP_013194043.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_013199222.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_013195512.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_013183779.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013187650.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013185812.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_013183315.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013193478.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_013192698.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013183319.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013186837.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013186341.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_013196555.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_013201072.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013187666.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_013192271.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_013200272.1 6 Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234 "Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" XP_013195693.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_013191114.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013195823.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013199067.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_013197807.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013195258.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_013197366.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_013188970.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_013183402.1 15 Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-176412 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C" XP_013195857.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_013194037.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_013192288.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_013183815.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013184794.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_013188401.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly" XP_013198525.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_013194194.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013195395.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" XP_013194308.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013199226.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013192331.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013199310.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_013187881.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013184908.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_013195154.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_013199771.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Collagen degradation";"MHC class II antigen presentation" XP_013188483.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013194434.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_013196446.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_013199043.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013186238.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_013186076.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013194056.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_013183046.1 7 Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-418594 "Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"G alpha (i) signalling events" XP_013189653.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones" XP_013186322.1 5 KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-5523;MetaCyc: PWY-7863 "Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis" XP_013194163.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_013190048.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_013193670.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013190722.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_013194527.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_013193699.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013194209.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_013189203.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_013187401.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_013193118.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013185416.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_013199688.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_013186077.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_013200263.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" XP_013188738.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_013190278.1 42 KEGG: 00410+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-5136;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-7606;MetaCyc: PWY-7779;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7654;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7401;MetaCyc: PWY-7094;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6583;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7656 "beta-Alanine metabolism";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Glutaryl-coa degradation";"Propanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid elongation";"Geraniol degradation";"Fatty acid degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Lysine degradation";"Phenylalanine metabolism";"Aminobenzoate degradation";"Limonene and pinene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"2-methylpropene degradation";"Caprolactam degradation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis" XP_013182979.1 7 Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484 "Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_013187749.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_013200258.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_013186886.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_013198614.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_013185385.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013195372.1 7 MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-46;MetaCyc: PWY-4984 "L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine biosynthesis";"Arginine and proline metabolism";"Urea cycle";"Putrescine biosynthesis III";"Urea cycle" XP_013199959.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_013189929.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013184899.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013192059.1 4 Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144 "IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" XP_013193227.1 14 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes" XP_013190026.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013195272.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013201163.1 9 KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00350+2.6.1.5;Reactome: R-HSA-8963684 "Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"Tyrosine catabolism" XP_013193600.1 5 Reactome: R-HSA-111458;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Formation of apoptosome";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_013195881.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_013192857.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4 "Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism" XP_013190304.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_013185383.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013185199.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_013197132.1 6 MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism" XP_013184223.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_013193766.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_013192220.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_013189656.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013192453.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013195160.1 4 Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Unwinding of DNA";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_013187251.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013186385.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013189145.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013199856.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_013183225.1 6 KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_013184864.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_013199256.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013186310.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434 "Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013186725.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_013189788.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_013187045.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013196877.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"HCMV Early Events";"Macroautophagy";"Separation of Sister Chromatids";"Intraflagellar transport";"COPI-mediated anterograde transport" XP_013191590.1 57 Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69481 "ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints" XP_013187833.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_013185302.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013185889.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013185747.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013198112.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_013183944.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013200503.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_013197428.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013185296.1 18 KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-7115;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622 "Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)" XP_013188372.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_013185762.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_013198365.1 9 Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "Processive synthesis on the lagging strand";"Polymerase switching";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" XP_013200240.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_013191360.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_013184516.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013200360.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_013184824.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_013190879.1 5 Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Protein ubiquitination";"Ub-specific processing proteases" XP_013183877.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013199860.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_013200537.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_013182981.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_013185043.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_013185591.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013192785.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_013184705.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_013184803.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_013200911.1 4 KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis" XP_013188036.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_013186442.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013200502.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_013190803.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013184907.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_013190896.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_013199528.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_013189828.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12 "Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_013191381.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013193280.1 12 Reactome: R-HSA-9619483;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852 "Activation of AMPK downstream of NMDARs";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Macroautophagy" XP_013186741.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013186186.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013194432.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_013184807.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_013187628.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013188995.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_013190078.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_013194613.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_013197624.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013199595.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_013183916.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_013184752.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_013184470.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_013192710.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323 "Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling" XP_013183449.1 10 Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886 "Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)" XP_013196305.1 3 Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism" XP_013200154.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_013197160.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_013197448.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013189813.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_013189790.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013184230.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013188490.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013187342.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013195029.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013197018.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_013200570.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_013195986.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013190669.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013185130.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_013197628.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013183342.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_013186739.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013189804.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_013193229.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids" XP_013196613.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_013183425.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013188099.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013192851.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_013185134.1 8 KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_013188438.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013199431.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013185836.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_013189888.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_013187288.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_013199886.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_013192964.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013195924.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_013182995.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_013193704.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_013187980.1 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88 "Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism" XP_013188366.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013200751.1 5 MetaCyc: PWY-7185;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2 "UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism" XP_013189578.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_013199694.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013196378.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013200574.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_013193296.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_013199144.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_013191766.1 5 KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_013192344.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_013194718.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013192353.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_013192992.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_013195323.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_013189745.1 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_013196015.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_013194902.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_013185554.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_013188493.1 12 KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Macroautophagy";"mTOR signaling pathway" XP_013198610.1 5 Reactome: R-HSA-189451;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_013192786.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_013188682.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_013186182.1 3 KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_013189379.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_013185715.1 10 MetaCyc: PWY-7187;Reactome: R-HSA-69205;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7210;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_013197315.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_013200955.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_013183553.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013183599.1 13 Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909 "Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)" XP_013191897.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013194342.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_013194145.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013194174.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_013191409.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013200760.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013189562.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_013194535.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_013190476.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_013199223.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_013184847.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013200843.1 7 KEGG: 00020+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71064;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation" XP_013192939.1 6 Reactome: R-HSA-913709;Reactome: R-HSA-5621480;Reactome: R-HSA-977068;Reactome: R-HSA-5083625;Reactome: R-HSA-5083636;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Dectin-2 family";"Termination of O-glycan biosynthesis";"Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)";"Defective GALNT12 causes colorectal cancer 1 (CRCS1)";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_013183160.1 3 Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664 "Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation" XP_013191883.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_013188105.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013200230.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_013185256.1 22 MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-7726;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-6958;MetaCyc: PWY-5080;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5353 "Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)" XP_013184140.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_013186290.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_013195377.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_013192015.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722 "Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)" XP_013194897.1 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4061 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I" XP_013192111.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_013193463.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_013183148.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_013196425.1 4 MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895 "2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism" XP_013195534.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013193161.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_013196796.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013183650.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013186386.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013194929.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013186457.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_013197504.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_013196518.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013193565.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Cilium Assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation" XP_013194042.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_013197035.1 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation" XP_013191633.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013197808.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_013189830.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013192330.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_013193708.1 9 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_013187239.1 6 Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "PKMTs methylate histone lysines";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_013200478.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_013195008.1 9 Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828 "Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Aggrephagy";"Clathrin-mediated endocytosis" XP_013196982.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013189712.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_013193336.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_013198039.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013184593.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013197561.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013184577.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_013187435.1 13 MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7141;MetaCyc: PWY-7659 "Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis" XP_013184542.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_013197951.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013201132.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_013193890.1 9 Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Thermogenesis" XP_013192306.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_013188269.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_013184758.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells" XP_013200912.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-382556 "CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Neddylation";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Degradation of GLI1 by the proteasome";"UCH proteinases";"ABC-family proteins mediated transport" XP_013195142.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013196959.1 4 Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013195734.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013194486.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013183107.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013188148.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013191775.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013193702.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629 "O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_013191247.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013187830.1 13 KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis" XP_013193522.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_013183374.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_013200557.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013186683.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013188230.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013200313.1 6 Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-7356;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907 "Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)" XP_013190307.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_013185209.1 7 MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25 "Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism" XP_013184373.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013199791.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_013192169.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation" XP_013186126.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013190688.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-2142789 "Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquinol biosynthesis" XP_013195259.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_013194162.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013198113.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013194744.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787 "PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state" XP_013183917.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_013194705.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-8953750 "Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6" XP_013187227.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_013199308.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_013199005.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_013187782.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013186260.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_013196411.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_013188873.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_013187005.1 18 Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167158 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex" XP_013183646.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_013197015.1 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" XP_013190147.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_013185452.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_013183596.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213 "Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs" XP_013183805.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013197181.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_013189565.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_013192388.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_013184372.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013191917.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_013183747.1 4 Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801 "Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion" XP_013184460.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_013194370.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_013199264.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013190023.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013189158.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_013201059.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_013199198.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_013189378.1 11 KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539 "Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Glutamate and glutamine metabolism" XP_013183180.1 8 Reactome: R-HSA-6783310;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Fanconi Anemia Pathway";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_013188993.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_013195022.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_013196492.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_013199975.1 8 MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation" XP_013187940.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation" XP_013194016.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_013193900.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_013187895.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290 "Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_013183873.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_013196820.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013187383.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_013185418.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013194197.1 7 Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539 "Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism" XP_013186489.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013190226.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_013198135.1 8 KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-6174 "Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)" XP_013188452.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013189639.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_013186731.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_013194439.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_013192137.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013192552.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013186069.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_013193211.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-381340 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation" XP_013193953.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013192520.1 8 Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5738;MetaCyc: PWY-7573;MetaCyc: PWY-5739;MetaCyc: PWY-5740 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis" XP_013190649.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_013194157.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013191001.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013193954.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013187649.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013196058.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_013184636.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_013185988.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013200507.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013191684.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013189620.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_013195391.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_013191225.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_013190899.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_013190091.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_013187314.1 13 MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Glutathione metabolism" XP_013192968.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013189195.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_013194500.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013184183.1 12 MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)" XP_013195271.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013185461.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" XP_013196773.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013192579.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_013186440.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013195521.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)" XP_013186329.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013194906.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013186022.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_013193847.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013184607.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_013197499.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013186986.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013188678.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013196677.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013197605.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-2514853 "Signal transduction by L1";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes" XP_013183687.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_013183809.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_013194967.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_013186291.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_013197167.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_013188859.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_013185914.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013186705.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013184617.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013184472.1 26 Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-8866654;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-174417;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-6804114;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"E3 ubiquitin ligases ubiquitinate target proteins";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_013189186.1 8 MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268 "Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate metabolism" XP_013201159.1 16 Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-1236394;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250347;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1251985;Reactome: R-HSA-5673001 "PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"SHC1 events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade" XP_013184477.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_013197755.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_013195368.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_013183228.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013199868.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_013193843.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013188453.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013190013.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013197698.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013196289.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013185057.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013184702.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_013194269.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_013192640.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_013182948.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_013198622.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_013190576.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_013199558.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" XP_013200099.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964 "Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_013199259.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013184323.1 18 Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1483166 "Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Synthesis of PA" XP_013200994.1 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" XP_013190102.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013190103.1 19 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-8876725;Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-6790901 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Protein methylation";"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol" XP_013191132.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013193872.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_013185115.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_013191104.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013196341.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_013200987.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-4608870;Reactome: R-HSA-8856825;Reactome: R-HSA-4641263;Reactome: R-HSA-4086398 "Clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Asymmetric localization of PCP proteins";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Ca2+ pathway" XP_013191005.1 4 KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-917937;Reactome: R-HSA-189483 "Porphyrin and chlorophyll metabolism";"Heme degradation I";"Iron uptake and transport";"Heme degradation" XP_013200962.1 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_013194236.1 8 KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817 "Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_013183577.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013197034.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381042 "Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"PERK regulates gene expression" XP_013190677.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013195018.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013197551.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013191383.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013196706.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_013193322.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_013197811.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013189147.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_013185560.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013194246.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_013194142.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_013194925.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813 "Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids" XP_013200444.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_013195218.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013200535.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013196348.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013183974.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013185721.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013183058.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_013195931.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_013197156.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine" XP_013198514.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_013191423.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_013191723.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_013196155.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_013192833.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013184329.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_013192441.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013192186.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_013185927.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_013187413.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013183763.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013192102.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_013185788.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_013185637.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013184182.1 12 MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms" XP_013196924.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_013192678.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" XP_013198073.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-6978 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II" XP_013187920.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_013189970.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013185809.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_013194520.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs" XP_013188140.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_013198680.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_013195023.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_013189228.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013199978.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_013197410.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_013183610.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_013188650.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7854 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_013197002.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_013192295.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_013195409.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_013183124.1 7 MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183 "3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol" XP_013192298.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013192157.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_013188759.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_013190800.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013189339.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013191505.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_013194193.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013187347.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_013186131.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013195424.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782 "Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis" XP_013191944.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_013200774.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013186787.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013193469.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013183546.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_013201053.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013189829.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_013198151.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013191312.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_013199120.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013185211.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013189535.1 6 MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II" XP_013186223.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_013191459.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_013198193.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_013191927.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_013190167.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013187529.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_013183424.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013192635.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_013183335.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_013198227.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_013184210.1 4 KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_013185458.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013190227.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_013189509.1 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_013190252.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013190279.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_013188787.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013184754.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_013194041.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013185970.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_013200314.1 5 KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;Reactome: R-HSA-193048;MetaCyc: PWY-6129 "N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_013184345.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013189553.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_013194464.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_013199637.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013183832.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_013185463.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013184312.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013200409.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_013191338.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_013192444.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_013182964.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_013196917.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_013187726.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling" XP_013194570.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_013190336.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_013194301.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013186785.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013190043.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_013186319.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013197512.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_013191832.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_013192704.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013187320.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_013191626.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_013184875.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_013196571.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013191095.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787 "Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state" XP_013183149.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_013194756.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013194501.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013196416.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis" XP_013190122.1 7 Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4 "Synthesis of PA";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_013186302.1 5 Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111463 "Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs" XP_013200646.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013195923.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_013197492.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013195952.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_013195200.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013200336.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_013197011.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_013187050.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-9610379;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-606279;Reactome: R-HSA-212300;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-427359;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2299718;Reactome: R-HSA-9609690;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-3214858;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-110331 "RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"HDACs deacetylate histones";"HDMs demethylate histones";"Estrogen-dependent gene expression";"HCMV Late Events";"Meiotic synapsis";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"PRC2 methylates histones and DNA";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SIRT1 negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Condensation of Prophase Chromosomes";"HCMV Early Events";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"RMTs methylate histone arginines";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine" XP_013198356.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_013187466.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_013192725.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_013189649.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14 "Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation" XP_013190452.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_013188823.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_013183106.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013190397.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_013198762.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_013199073.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation" XP_013183797.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_013199626.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013192337.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_013183783.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013187267.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_013192647.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013184941.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_013200050.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_013190872.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Methylation" XP_013193762.1 7 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-429947 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Deadenylation of mRNA" XP_013188126.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013196913.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_013186541.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013194831.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_013191985.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_013195425.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_013191630.1 6 Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5685939 "Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)" XP_013189026.1 12 Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1 "DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"Thermogenesis";"Rho GTPase cycle";"Relaxin signaling pathway";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"NRAGE signals death through JNK";"Human cytomegalovirus infection" XP_013188439.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013188518.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_013191171.1 40 Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135 "Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER" XP_013196972.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013194094.1 17 Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-69166 "Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Polymerase switching";"Dual Incision in GG-NER";"Removal of the Flap Intermediate" XP_013199118.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903 "Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy" XP_013183029.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_013185114.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_013200620.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013198117.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013192493.1 3 Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-70263 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Gluconeogenesis" XP_013188877.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_013200047.1 11 Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340 "Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation" XP_013186694.1 33 Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-73863;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of RNA Pol II elongation complex" XP_013188132.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_013186841.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013191318.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013182994.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_013200772.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013183933.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_013192546.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026 "VLDL assembly";"Scavenging by Class B Receptors";"Chylomicron remodeling";"LDL clearance";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"VLDL clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Scavenging by Class A Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Chylomicron clearance" XP_013196223.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_013185950.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_013183275.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013188858.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_013197258.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013184145.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_013191687.1 20 Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Polymerase switching";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_013195256.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_013185719.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013194651.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013192287.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_013183397.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_013193077.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_013187554.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013201254.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_013199870.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013200818.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_013184020.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_013197729.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013190354.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_013191787.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_013186583.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_013198934.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013198607.1 5 MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336 "2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_013184240.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_013197566.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_013196797.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_013186594.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013190850.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724 "SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription" XP_013196640.1 57 Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236 "Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"UCH proteinases";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_013191367.1 16 Reactome: R-HSA-76066;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73776;Reactome: R-HSA-73780;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_013188217.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557 "Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis" XP_013183532.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013187083.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_013183263.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_013187943.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_013197390.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_013200431.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_013192114.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_013185932.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013198554.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_013194309.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013189697.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_013184664.1 2 KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)" XP_013191270.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_013195836.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_013191667.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_013199478.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state" XP_013196614.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_013196235.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_013185769.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Polo-like kinase mediated events" XP_013195530.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013195866.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_013197993.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane" XP_013190818.1 13 Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52 "Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_013200212.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013195944.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013199802.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_013197163.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_013191081.1 6 MetaCyc: PWY-6731;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737 "Starch degradation III";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V" XP_013198115.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_013196307.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_013183056.1 179 Reactome: R-HSA-2894862;Reactome: R-HSA-5693565;Reactome: R-HSA-3785653;Reactome: R-HSA-450408;Reactome: R-HSA-201681;Reactome: R-HSA-168638;Reactome: R-HSA-1295596;Reactome: R-HSA-917937;Reactome: R-HSA-2122948;Reactome: R-HSA-8948747;Reactome: R-HSA-5668541;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-936440;Reactome: R-HSA-156902;Reactome: R-HSA-179409;Reactome: R-HSA-1253288;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-445989;Reactome: R-HSA-5205685;Reactome: R-HSA-3134975;Reactome: R-HSA-4641263;Reactome: R-HSA-5655862;Reactome: R-HSA-5362768;Reactome: R-HSA-2691232;Reactome: R-HSA-168927;Reactome: R-HSA-209560;Reactome: R-HSA-1799339;Reactome: R-HSA-8948751;Reactome: R-HSA-5696395;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-5687128;Reactome: R-HSA-8849469;Reactome: R-HSA-6804757;Reactome: R-HSA-156827;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5696400;Reactome: R-HSA-5675482;Reactome: R-HSA-72689;Reactome: R-HSA-5656169;Reactome: R-HSA-9645460;Reactome: R-HSA-2122947;Reactome: R-HSA-5610780;Reactome: R-HSA-5696394;Reactome: R-HSA-69601;Reactome: R-HSA-72764;Reactome: R-HSA-937072;Reactome: R-HSA-8876493;Reactome: R-HSA-450302;Reactome: R-HSA-975957;Reactome: R-HSA-6783310;Reactome: R-HSA-977225;Reactome: R-HSA-9613829;Reactome: R-HSA-5610785;Reactome: R-HSA-2173796;Reactome: R-HSA-69541;Reactome: R-HSA-912631;Reactome: R-HSA-5357905;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-9615710;Reactome: R-HSA-8939902;Reactome: R-HSA-937041;Reactome: R-HSA-175474;Reactome: R-HSA-936964;Reactome: R-HSA-1236382;Reactome: R-HSA-2871837;Reactome: R-HSA-9636383;Reactome: R-HSA-180534;Reactome: R-HSA-209543;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-5656121;Reactome: R-HSA-180585;Reactome: R-HSA-2979096;Reactome: R-HSA-917729;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-937039;Reactome: R-HSA-5689896;Reactome: R-HSA-1236974;Reactome: R-HSA-110312;Reactome: R-HSA-975110;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-6782210;Reactome: R-HSA-5654726;Reactome: R-HSA-9013973;Reactome: R-HSA-8866654;Reactome: R-HSA-2408557;Reactome: R-HSA-4641258;Reactome: R-HSA-1169408;Reactome: R-HSA-5658442;Reactome: R-HSA-8866652;Reactome: R-HSA-2173791;Reactome: R-HSA-975144;Reactome: R-HSA-8939236;Reactome: R-HSA-1358803;Reactome: R-HSA-6782135;Reactome: R-HSA-192823;Reactome: R-HSA-3769402;Reactome: R-HSA-9604323;Reactome: R-HSA-6781823;Reactome: R-HSA-2672351;Reactome: R-HSA-2559585;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-6781827;Reactome: R-HSA-1169091;Reactome: R-HSA-9646399;Reactome: R-HSA-5358346;Reactome: R-HSA-2173788;Reactome: R-HSA-5684264;Reactome: R-HSA-3322077;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-168928;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5693607;Reactome: R-HSA-382556;Reactome: R-HSA-182971;Reactome: R-HSA-2644606;Reactome: R-HSA-532668;Reactome: R-HSA-162588;Reactome: R-HSA-5696397;Reactome: R-HSA-349425;Reactome: R-HSA-6804760;Reactome: R-HSA-975163;Reactome: R-HSA-9013507;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5689901;Reactome: R-HSA-2565942;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-8875360;Reactome: R-HSA-205043;Reactome: R-HSA-6791226;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-9033241;Reactome: R-HSA-5685942;Reactome: R-HSA-174490;Reactome: R-HSA-68949;Reactome: R-HSA-5675221;Reactome: R-HSA-6807004;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-8856828;Reactome: R-HSA-901032;Reactome: R-HSA-110314;Reactome: R-HSA-400253;Reactome: R-HSA-6804756;Reactome: R-HSA-69017;Reactome: R-HSA-2173795;Reactome: R-HSA-8856825;Reactome: R-HSA-5654733;Reactome: R-HSA-8863795;Reactome: R-HSA-975956;Reactome: R-HSA-5357956;Reactome: R-HSA-187577;Reactome: R-HSA-5654732;Reactome: R-HSA-5689603;Reactome: R-HSA-5689877;Reactome: R-HSA-9637628;Reactome: R-HSA-174048;Reactome: R-HSA-110320 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myoclonic epilepsy of Lafora";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TCF dependent signaling in response to WNT";"NOD1/2 Signaling Pathway";"Spry regulation of FGF signaling";"Iron uptake and transport";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of PTEN localization";"TNFR2 non-canonical NF-kB pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Negative regulators of DDX58/IFIH1 signaling";"Peptide chain elongation";"APC-Cdc20 mediated degradation of Nek2A";"Downregulation of ERBB4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Pink/Parkin Mediated Mitophagy";"Regulation of innate immune responses to cytosolic DNA";"Regulation of FZD by ubiquitination";"Translesion synthesis by POLK";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1, RIP1-mediated IKK complex recruitment";"NF-kB is activated and signals survival";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of PTEN stability and activity";"Formation of Incision Complex in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"MAPK6/MAPK4 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of TP53 Degradation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dual Incision in GG-NER";"Regulation of necroptotic cell death";"Formation of a pool of free 40S subunits";"Termination of translesion DNA synthesis";"Alpha-protein kinase 1 signaling pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI1 by the proteasome";"DNA Damage Recognition in GG-NER";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Eukaryotic Translation Termination";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"InlA-mediated entry of Listeria monocytogenes into host cells";"activated TAK1 mediates p38 MAPK activation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Fanconi Anemia Pathway";"Amyloid fiber formation";"Chaperone Mediated Autophagy";"GLI3 is processed to GLI3R by the proteasome";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Stabilization of p53";"Regulation of signaling by CBL";"Regulation of TNFR1 signaling";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Late endosomal microautophagy";"Regulation of RUNX2 expression and activity";"IKK complex recruitment mediated by RIP1";"Assembly Of The HIV Virion";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"FCERI mediated NF-kB activation";"Prevention of phagosomal-lysosomal fusion";"Vpu mediated degradation of CD4";"p75NTR recruits signalling complexes";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translesion synthesis by POLI";"Vif-mediated degradation of APOBEC3G";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Endosomal Sorting Complex Required For Transport (ESCRT)";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Ub-specific processing proteases";"IRAK1 recruits IKK complex";"Ovarian tumor domain proteases";"ER-Phagosome pathway";"Translesion synthesis by REV1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Negative regulation of FGFR1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"E3 ubiquitin ligases ubiquitinate target proteins";"Selenocysteine synthesis";"Degradation of DVL";"ISG15 antiviral mechanism";"Regulation of RAS by GAPs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2:ERBB3 signaling";"Dual incision in TC-NER";"Viral mRNA Translation";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of NOTCH4 signaling";"Formation of TC-NER Pre-Incision Complex";"Stimuli-sensing channels";"Oncogene Induced Senescence";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of NF-kappaB in B cells";"Aggrephagy";"Hedgehog ligand biogenesis";"Downregulation of TGF-beta receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Glycogen synthesis";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Processing of DNA double-strand break ends";"ABC-family proteins mediated transport";"EGFR downregulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Budding and maturation of HIV virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Activity through Methylation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Metalloprotease DUBs";"Regulation of PLK1 Activity at G2/M Transition";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"NRIF signals cell death from the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"Peroxisomal protein import";"HDR through Homologous Recombination (HRR)";"Membrane binding and targetting of GAG proteins";"Orc1 removal from chromatin";"Negative regulation of MAPK pathway";"Negative regulation of MET activity";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Clathrin-mediated endocytosis";"ER Quality Control Compartment (ERQC)";"Recognition of DNA damage by PCNA-containing replication complex";"Circadian Clock";"Regulation of TP53 Activity through Phosphorylation";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR4 signaling";"Downregulation of ERBB2 signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TNFR1-induced NFkappaB signaling pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of FGFR3 signaling";"UCH proteinases";"Josephin domain DUBs";"Modulation by Mtb of host immune system";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion Synthesis by POLH" XP_013196971.1 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_013199346.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013198278.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_013196394.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_013185701.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_013183733.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013196119.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013186324.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013186726.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_013186622.1 10 KEGG: 00640+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-5022;Reactome: R-HSA-916853 "Propanoate metabolism";"4-aminobutanoate degradation III";"Butanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V";"Degradation of GABA" XP_013196222.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_013184968.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_013190914.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013198634.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6798695;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex" XP_013194404.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013198689.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013188214.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-380972 "Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_013198215.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013195862.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_013201083.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_013187828.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013197979.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013183086.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013185012.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_013200871.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_013196366.1 8 KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171 "Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_013191653.1 23 Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-8964616;Reactome: R-HSA-202040 "G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through CDC42";"G-protein activation" XP_013185340.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013193050.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013197016.1 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" XP_013192051.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_013189693.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013190809.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013183942.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_013199525.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013194394.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_013184560.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_013200097.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013185585.1 6 Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-73933 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)" XP_013191450.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5873 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_013191712.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013197452.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013198687.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013198228.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013192091.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69183 "DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the lagging strand" XP_013187668.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_013198259.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_013192324.1 10 KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"RSK activation";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway" XP_013190374.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_013189097.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_013198704.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013191996.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013184154.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Gap junction degradation";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_013196350.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013195020.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013196292.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_013193682.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_013191838.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_013185577.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_013198080.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_013195745.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_013197570.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013188246.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_013184417.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013189545.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_013197004.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013199250.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_013188402.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_013190141.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation" XP_013184523.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_013183938.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_013188653.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-735;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337 "Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_013200603.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_013192194.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135 "Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER" XP_013186899.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha" XP_013192726.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_013199378.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684 "Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state" XP_013189654.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013197012.1 6 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427359 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression" XP_013187095.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex" XP_013190807.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013182959.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_013185619.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013198828.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013184503.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013192269.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_013191237.1 10 KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11 "Methane metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" XP_013190754.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_013188312.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_013184541.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013197717.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013190522.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013185731.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_013186546.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013195207.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_013183799.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_013196024.1 24 Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-9609690 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events" XP_013198941.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013197009.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_013199762.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_013194229.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013188253.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes" XP_013198825.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013200944.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_013190805.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013198608.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_013196428.1 6 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_013185667.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_013196424.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013185106.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013194289.1 9 Reactome: R-HSA-156590;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061 "Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I" XP_013195260.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_013197430.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_013196213.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_013196355.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013187488.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013188335.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_013199793.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_013188183.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013195883.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013188189.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_013184405.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_013186592.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013193095.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_013183680.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_013187717.1 15 Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290 "Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation" XP_013198190.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_013195716.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013186480.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_013193860.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_013192582.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_013194900.1 13 Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-5674400 "PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_013198220.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_013195748.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_013186859.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013196079.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291 "Neutrophil degranulation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C" XP_013199038.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_013194238.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013200879.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013190731.1 24 Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-202424;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1 "RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"Downstream TCR signaling";"Human cytomegalovirus infection";"RSK activation";"mTOR signaling pathway";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection" XP_013198450.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013188906.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013190181.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_013190344.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_013192505.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013187300.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_013197788.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013183676.1 34 Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-69231 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1" XP_013187273.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013193693.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_013182856.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013187663.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_013186046.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013189973.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_013184685.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013201183.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013183444.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852 "Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy" XP_013198322.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013193173.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_013193119.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_013190819.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52 "Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_013195778.1 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" XP_013188302.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013185516.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_013190274.1 9 MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism" XP_013194248.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_013185151.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_013196908.1 13 Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157 "Collagen chain trimerization";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"ECM proteoglycans";"Collagen degradation";"Extracellular matrix organization";"Anchoring fibril formation";"Laminin interactions" XP_013196529.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013193663.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013197632.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_013192462.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_013195688.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013194658.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013183481.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" XP_013193786.1 7 KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"ATP biosynthesis";"Mitochondrial protein import";"Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_013187133.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_013199454.1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473 "Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint" XP_013184932.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_013190031.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013198749.1 30 Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-2644607;Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-2565942;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1170546;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902 "Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Circadian Clock";"Regulation of PLK1 Activity at G2/M Transition";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Neddylation";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Prolactin receptor signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity" XP_013189384.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013190550.1 5 Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_013185475.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_013190450.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_013184122.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013183325.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_013191773.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013184983.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_013182989.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_013198547.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-5682294 "ABC transporters in lipid homeostasis";"Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B" XP_013199493.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013195328.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013184493.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_013200741.1 4 Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus" XP_013190261.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" XP_013193264.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex" XP_013197909.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962 "Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex" XP_013187825.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_013194685.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_013199851.1 5 Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185 "Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I" XP_013190469.1 33 Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4085377 "SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins" XP_013190095.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_013193447.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_013200691.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013191238.1 10 KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11 "Fructose and mannose metabolism";"Methane metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" XP_013193683.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_013189146.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_013195006.1 9 Reactome: R-HSA-8856825;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-8856828;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9646399;Reactome: R-HSA-5627083;Reactome: R-HSA-5689880 "Cargo recognition for clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Aggrephagy";"RHO GTPases regulate CFTR trafficking";"Ub-specific processing proteases" XP_013184640.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_013193580.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_013186265.1 15 Reactome: R-HSA-5637810;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9665233;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665250;Reactome: R-HSA-9652282;Reactome: R-HSA-9665246 "Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to AEE788";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib" XP_013186670.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013183543.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_013189330.1 11 Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling" XP_013190568.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_013195907.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1 "Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (s) signalling events";"Purine metabolism" XP_013193357.1 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol" XP_013194154.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_013188519.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_013187270.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" XP_013188037.1 12 Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5857 "Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_013185905.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_013191026.1 33 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-69656;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape" XP_013184340.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013195890.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964 "IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_013188227.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013194283.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_013183586.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_013198929.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013197933.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_013190859.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013199806.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013183458.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_013191905.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013197697.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013189373.1 5 MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_013195096.1 5 KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism" XP_013200966.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013190810.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013188942.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736 "Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Long-term potentiation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Assembly and cell surface presentation of NMDA receptors" XP_013192711.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858 "Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"UCH proteinases";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Regulation of RUNX3 expression and activity" XP_013197409.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013193158.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_013195634.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_013201113.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_013194208.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_013191663.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895 "MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Neddylation";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis" XP_013194949.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_013184897.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013184194.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013197601.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013193917.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013193032.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013188407.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013186590.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013190422.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_013185410.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013194090.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013187506.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_013193502.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013187423.1 10 MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781 "Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"PPARA activates gene expression" XP_013192202.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_013200351.1 7 MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol" XP_013187956.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_013196272.1 22 MetaCyc: PWY-5353;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-7053;MetaCyc: PWY-7727 "Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)" XP_013186817.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013200665.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013185274.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_013199918.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_013199882.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013193254.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013199477.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_013196704.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013190821.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013182822.1 18 MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7115;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III";"Phenylalanine metabolism";"Arginine and proline metabolism";"Arginine biosynthesis";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tyrosine metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_013188695.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_013191175.1 7 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC" XP_013195597.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_013193117.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013192339.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-6502 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I" XP_013197989.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_013200798.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-195253 "AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex" XP_013182901.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_013187901.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13 "Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system" XP_013188732.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013184809.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_013193366.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_013194820.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013186948.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013196775.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_013201114.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_013183678.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013184181.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013194186.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013188139.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_013196858.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_013198839.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_013184629.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_013188383.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_013190878.1 5 Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity" XP_013200580.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_013183205.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_013191135.1 14 Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-2173788 "Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling" XP_013192061.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013187380.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport" XP_013200998.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_013198594.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_013190990.1 2 Reactome: R-HSA-3299685;Reactome: R-HSA-211945 "Detoxification of Reactive Oxygen Species";"Phase I - Functionalization of compounds" XP_013198095.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_013189636.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013199381.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922 "Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium" XP_013193395.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_013185969.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_013185983.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_013187302.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_013194321.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_013182827.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013194030.1 8 MetaCyc: PWY-7734;MetaCyc: PWY-7765;MetaCyc: PWY-7733;MetaCyc: PWY-5651;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9 "Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism" XP_013186903.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013183739.1 4 MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22 "Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism" XP_013192081.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_013193701.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629 "O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_013185837.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_013194708.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_013186937.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133 "Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1" XP_013193099.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_013192914.1 16 Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-983168 "HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013197607.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191 "Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC" XP_013187398.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013199066.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091 "G1/S-Specific Transcription";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching" XP_013189105.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013183795.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013188224.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013200663.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_013183470.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_013186047.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_013201064.1 3 Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999 "Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_013188338.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013187339.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013189887.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_013195516.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_013200568.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_013193606.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013198265.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases" XP_013185651.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013195088.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)" XP_013196620.1 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation" XP_013193383.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" XP_013186679.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013187373.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_013198258.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_013182886.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013199247.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_013188757.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_013194560.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_013186453.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013196862.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_013187922.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013184468.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_013195058.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_013191780.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_013200467.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_013192902.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex" XP_013188209.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_013183955.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_013184863.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_013185328.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_013195038.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_013189595.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_013186509.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation" XP_013182854.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_013191852.1 10 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_013189166.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_013189067.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection" XP_013194859.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_013184945.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_013185479.1 25 Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-9018519;Reactome: R-HSA-8939247;Reactome: R-HSA-8939242;Reactome: R-HSA-8941326;Reactome: R-HSA-8931987;Reactome: R-HSA-8941332;Reactome: R-HSA-8941858;Reactome: R-HSA-8936459;Reactome: R-HSA-8951936;Reactome: R-HSA-8951911;Reactome: R-HSA-8941284;Reactome: R-HSA-8877330;Reactome: R-HSA-8939246;Reactome: R-HSA-8939245;Reactome: R-HSA-8939236;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-9616222;Reactome: R-HSA-8878166;Reactome: R-HSA-8949275;Reactome: R-HSA-8941333;Reactome: R-HSA-8934593;Reactome: R-HSA-8935964 "RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates bone development";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX3 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates p14-ARF";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates chondrocyte maturation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by RUNX2";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates expression of components of tight junctions" XP_013186287.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013199271.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_013184651.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_013186004.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_013188675.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168276 "Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways" XP_013193962.1 27 Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333 "Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"HCMV Early Events";"snRNP Assembly";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_013188176.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013201248.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_013198023.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_013200009.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013191606.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013195647.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_013192644.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013197829.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013201236.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013199428.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013187692.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_013196795.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013187170.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013188854.1 29 Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6803204;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6803207;Reactome: R-HSA-5693616;Reactome: R-HSA-69541;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693565;KEGG: 05170+2.7.11.1 "G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human papillomavirus infection";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Presynaptic phase of homologous DNA pairing and strand exchange";"Stabilization of p53";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Human cytomegalovirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human immunodeficiency virus 1 infection" XP_013199684.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_013189276.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013188826.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013193131.1 7 MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403 "Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_013187191.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6607;Reactome: R-HSA-8851680 "Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine catabolism";"Theophylline degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions" XP_013186804.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_013191537.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013192809.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_013198975.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135 "Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER" XP_013194951.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_013186455.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_013192389.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_013196265.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_013191045.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_013197959.1 9 KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_013190811.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013195355.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_013184967.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013195970.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_013192670.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_013194302.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013186788.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_013189779.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013190041.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_013195755.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013197052.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_013189974.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_013190860.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_013183400.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_013183930.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013192218.1 4 KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_013199177.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_013196753.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_013190994.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_013197383.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013189416.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013183450.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300 "HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors" XP_013200237.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_013183837.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013187298.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013190523.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_013195401.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_013196475.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_013199321.1 4 KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_013201121.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013194505.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013192181.1 4 KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_013192641.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_013183773.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_013182985.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_013183669.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013191960.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013196674.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013191064.1 12 Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9 "Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Starch and sucrose metabolism" XP_013200553.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013200593.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013199801.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_013189382.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_013193147.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750 "Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6" XP_013184911.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_013190192.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_013189241.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_013185026.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_013189194.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_013200028.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013192781.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013195274.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013200217.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_013191396.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_013190837.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013197415.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_013187918.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_013193601.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013184393.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_013191685.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013195804.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_013188250.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013187378.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_013188212.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_013191121.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013189332.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013192001.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013201078.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013201003.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013197270.1 5 MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" XP_013200323.1 5 KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;Reactome: R-HSA-193048;MetaCyc: PWY-6129 "N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_013186133.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013190590.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_013196689.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_013190037.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_013192712.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013195827.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013187582.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_013197405.1 57 Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-1236974 "CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway" XP_013192495.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_013194508.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013197726.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_013195146.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295 "Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"MHC class II antigen presentation" XP_013185411.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_013199599.1 6 Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788 "Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling" XP_013200300.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation" XP_013193206.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_013186564.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013199603.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013190981.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_013196941.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_013199496.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013197001.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_013189800.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013188020.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_013196130.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013183426.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013191999.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013190320.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_013183576.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_013186969.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_013185682.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_013191813.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_013193421.1 6 Reactome: R-HSA-196780;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;MetaCyc: PWY-6122 "Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II" XP_013195129.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_013191180.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013194914.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_013185805.1 14 MetaCyc: PWY-5104;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-7767;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5101;MetaCyc: PWY-5078 "L-isoleucine biosynthesis IV";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis II";"L-isoleucine degradation II" XP_013185654.1 4 KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7849;MetaCyc: PWY-7394 "Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Urate conversion to allantoin II" XP_013199916.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_013191235.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7385 "Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)" XP_013187721.1 6 KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980 "Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis" XP_013192783.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs" XP_013184543.1 5 MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_013191736.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-113507 "CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_013199766.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_013188184.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013185573.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling" XP_013188723.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013194286.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013189351.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_013182868.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_013185455.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013190423.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_013197780.1 18 Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism" XP_013188405.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_013200577.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_013192602.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013197929.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_013184713.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013192511.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013193248.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013196063.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_013184004.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_013185524.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013187479.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013187559.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013190224.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013185149.1 6 KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_013200589.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013187942.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_013200223.1 10 KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001 "Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_013198590.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_013188100.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_013186350.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013191305.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013197707.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_013187644.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_013200925.1 3 Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457 "Ca2+ pathway";"Rap1 signalling";"cGMP effects" XP_013183262.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-389957 "Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_013191248.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013196052.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013196141.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_013193889.1 9 Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_013196629.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184 "ABC-family proteins mediated transport";"UCH proteinases";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Neddylation";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_013193515.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_013188897.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013197227.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_013184692.1 9 MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6147 "Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I" XP_013197033.1 7 Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-983170 "ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Platelet degranulation";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_013191892.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013188883.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_013197123.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013191937.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013187430.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_013197353.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013189807.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013200551.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013188649.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7854;Reactome: R-HSA-9033241 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import" XP_013183914.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_013192739.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013192350.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_013200445.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport" XP_013188286.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013185581.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_013193612.1 5 Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;MetaCyc: PWY-6558 "Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)" XP_013191853.1 10 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9648895 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency" XP_013189240.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_013188830.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_013183304.1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" XP_013197486.1 7 Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11 "Synthesis of PI";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system" XP_013196680.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013184677.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_013184054.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013190839.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013182885.1 14 Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696397 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_013194498.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013185669.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_013185131.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_013197394.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_013199221.1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_013196427.1 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_013184103.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013188242.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013192134.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013195044.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013200274.1 6 MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234 "Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" XP_013191461.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_013194752.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013195889.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade" XP_013187026.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_013193033.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_013191577.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-69017 "Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6" XP_013199596.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_013185720.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013198248.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_013183759.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_013188315.1 7 MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" XP_013196191.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_013189752.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_013199333.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013186560.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_013184870.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_013188821.1 15 MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7383 "Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Pyruvate metabolism";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_013191424.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013183371.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_013200341.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013191785.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013195288.1 3 Reactome: R-HSA-202433;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_013197966.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013198189.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_013188052.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013187908.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290 "Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_013187832.1 13 KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2160916 "Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation" XP_013183024.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013185361.1 6 KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124 "Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II" XP_013184693.1 9 MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6703;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6147 "Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I" XP_013201131.1 5 KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III" XP_013196479.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_013189566.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_013194895.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001 "Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_013192665.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013191768.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013194239.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_013185578.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013183941.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_013191137.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-5663220 "MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins" XP_013183850.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_013200378.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_013191279.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_013186781.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013186091.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013185109.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013189072.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_013199892.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" XP_013197133.1 6 MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" XP_013184729.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_013196000.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_013200578.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_013183757.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013192476.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013186239.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013196233.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_013198421.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013198197.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69091 "Translesion synthesis by REV1";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching" XP_013192215.1 8 KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Thermogenesis" XP_013198745.1 12 Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947 "Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription" XP_013183129.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_013197608.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903 "Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy" XP_013200833.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013183436.1 12 MetaCyc: PWY-6936;MetaCyc: PWY-6842;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13 "Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism" XP_013183658.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013192088.1 17 Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-983168 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013193885.1 9 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection" XP_013189781.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_013191399.1 7 KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_013198438.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_013189502.1 5 KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4 "Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism" XP_013196186.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_013194503.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013197838.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013194965.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_013199045.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_013186463.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_013191556.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013194274.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_013199855.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_013193055.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013194367.1 30 Reactome: R-HSA-9614399;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-211163;Reactome: R-HSA-199418;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-8948751;Reactome: R-HSA-69656;Reactome: R-HSA-5674400;Reactome: R-HSA-8941332;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-198693;Reactome: R-HSA-389513;KEGG: 04151+2.7.11.1;Reactome: R-HSA-111447;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-6804758;Reactome: R-HSA-5218920;Reactome: R-HSA-9634638;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-1358803;Reactome: R-HSA-6804759 "Regulation of localization of FOXO transcription factors";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"AKT-mediated inactivation of FOXO1A";"Negative regulation of the PI3K/AKT network";"Human cytomegalovirus infection";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN stability and activity";"Cyclin A:Cdk2-associated events at S phase entry";"Constitutive Signaling by AKT1 E17K in Cancer";"RUNX2 regulates genes involved in cell migration";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the nucleus";"CTLA4 inhibitory signaling";"PI3K-Akt signaling pathway";"Activation of BAD and translocation to mitochondria";"Thermogenesis";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Acetylation";"VEGFR2 mediated vascular permeability";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Human papillomavirus infection";"mTOR signaling pathway";"Cyclin E associated events during G1/S transition";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Association with Co-factors" XP_013199076.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-194840 "Transcriptional activation of mitochondrial biogenesis";"Rho GTPase cycle" XP_013184819.1 11 MetaCyc: PWY-6174;MetaCyc: PWY-6383;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7391;MetaCyc: PWY-7560;Reactome: R-HSA-191273 "Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)";"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis" XP_013196476.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_013183932.1 9 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781827 "DNA Damage Recognition in GG-NER";"Neddylation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_013198553.1 31 MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-7746;MetaCyc: PWY-8049;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-6282;Reactome: R-HSA-199220;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-7723 "Superpathway of mycolate biosynthesis";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Vitamin B5 (pantothenate) metabolism";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence" XP_013184612.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_013201095.1 4 KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism" XP_013185896.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_013199429.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_013187682.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_013193849.1 5 KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism" XP_013184722.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_013191942.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013198174.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_013192176.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214815 "Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones" XP_013194399.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013198430.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_013186216.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_013185116.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_013187250.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013193420.1 12 Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2 "Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"One carbon pool by folate" XP_013187849.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_013183311.1 12 MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-6842;MetaCyc: PWY-601;MetaCyc: PWY-7901 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine" XP_013198586.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_013191756.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013190121.1 7 MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4 "Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Synthesis of PG";"Synthesis of PA";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism" XP_013190730.1 24 KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Human papillomavirus infection";"RSK activation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"Activation of AKT2";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Thermogenesis";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway" XP_013183945.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013199407.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_013194490.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013185119.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_013198283.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_013185365.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_013186335.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_013186545.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_013187751.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013183013.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_013189155.1 13 Reactome: R-HSA-2871796;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;Reactome: R-HSA-2871809 "FCERI mediated MAPK activation";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated Ca+2 mobilization" XP_013190529.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_013190040.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_013188260.1 18 Reactome: R-HSA-1482839;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PE";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism" XP_013197722.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013184212.1 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_013193961.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_013188941.1 6 MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose metabolism" XP_013183598.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013191562.1 5 MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20 "Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" XP_013193986.1 5 Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_013187344.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-9609523 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_013198599.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013186930.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013183121.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013188277.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_013196762.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013190212.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors" XP_013194126.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_013191159.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_013191122.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013199964.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_013199219.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013191581.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_013194731.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_013196156.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_013200612.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_013196039.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_013193764.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_013197273.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_013197719.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013189889.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_013191742.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013183780.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_013196993.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_013196343.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_013189331.1 11 Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558 "Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_013199145.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013188091.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013196589.1 13 Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-381676 "PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Ca2+ pathway";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_013194550.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_013199873.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013187467.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-9020702 "Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Downstream TCR signaling";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling" XP_013189952.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013185571.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013192925.1 9 MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism" XP_013192707.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013192863.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_013188475.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013195984.1 2 MetaCyc: PWY-6938;Reactome: R-HSA-430039 "NADH repair";"mRNA decay by 5' to 3' exoribonuclease" XP_013192872.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_013200337.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013188763.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_013188044.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_013196729.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_013192577.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_013184698.1 5 Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-901032 "Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)" XP_013190028.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013200926.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_013198198.1 18 KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6638 "Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Arginine biosynthesis";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Sulfolactate degradation III" XP_013195969.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_013199345.1 58 Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5689901;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442 "CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Downstream TCR signaling";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Metalloprotease DUBs";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs" XP_013200564.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013188805.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815 "Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D" XP_013186878.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300 "SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA" XP_013192530.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_013192871.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_013200632.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_013187276.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy" XP_013191056.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_013196678.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_013197718.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013194898.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041 "Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle" XP_013188875.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013194313.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_013191439.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_013184867.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_013200550.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013194773.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_013192107.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_013192807.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013188443.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_013199914.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_013198219.1 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_013199731.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013190559.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_013194539.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_013187391.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_013190459.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013185882.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-141430 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_013184310.1 52 Reactome: R-HSA-6781823;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-73980;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-1834949;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-73762 "Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cytosolic sensors of pathogen-associated DNA";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation" XP_013196822.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_013187125.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_013183564.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_013200207.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_013199811.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013195286.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_013199579.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013193671.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013185133.1 8 MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_013183918.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_013188612.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_013186620.1 7 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_013200952.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013197349.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_013198543.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_013189662.1 4 KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6 "Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate" XP_013192639.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_013197528.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_013190629.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-5696400 "Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER" XP_013187665.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_013185572.1 5 Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-5674400 "mTORC1-mediated signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_013191217.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_013191234.1 10 MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861 "Glycolysis IV (plant cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Methane metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_013195310.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" XP_013188138.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_013195845.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_013186495.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013184155.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-389513 "RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling" XP_013186780.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013200848.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_013195331.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013186978.1 8 Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_013192238.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing" XP_013198560.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_013191410.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_013191741.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_013193763.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_013193169.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013185623.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013183231.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_013198309.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol" XP_013190905.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013192566.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013192468.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013183592.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_013195042.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_013195632.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_013193816.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_013200622.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013189584.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_013193514.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013192686.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_013199307.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_013189591.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013198326.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013199439.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_013185921.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_013201056.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445 "Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation" XP_013194720.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013190926.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_013195600.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_013193120.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_013185147.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_013197024.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_013195685.1 8 Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_013183734.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013197333.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_013196582.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_013185826.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_013184019.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292 "Neutrophil degranulation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome" XP_013198593.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_013187812.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013194304.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_013184119.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_013185088.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_013196933.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_013192016.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_013182982.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_013201107.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_013199385.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_013195075.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_013195346.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_013191063.1 12 MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9 "Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Sucrose biosynthesis II";"Galactose metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism" XP_013187738.1 52 Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-1834949;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-73980;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-72203 "B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cytosolic sensors of pathogen-associated DNA";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA" XP_013189341.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013184548.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013199481.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_013192104.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_013201154.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013190662.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_013191342.1 5 MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_013192229.1 4 Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-6809583 "Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Retinoid metabolism disease events" XP_013188850.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_013190082.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_013200900.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_013193412.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_013192198.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013197171.1 5 KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_013193449.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_013187469.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_013196349.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_013187001.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_013194495.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829 "Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_013198894.1 8 MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-7765;MetaCyc: PWY-7733;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-5651 "3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_013184481.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_013183934.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_013196016.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_013188003.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_013190126.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_013195968.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_013188914.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_013198880.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_013197668.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_013199094.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013199204.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_013191315.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013184956.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_013187019.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013185485.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_013189289.1 12 Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72702 "Deadenylation of mRNA";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition" XP_013192705.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013194957.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013193690.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013189136.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_013187082.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013198559.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_013189237.1 14 MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-1622;MetaCyc: PWY-6886;MetaCyc: PWY-2221 "Rubisco shunt";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation I (serine pathway)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_013188440.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013194497.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013197473.1 4 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism" XP_013193241.1 10 Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23 "HS-GAG degradation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Other glycan degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism" XP_013200683.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013200224.1 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-7559 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway" XP_013197849.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_013194968.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_013193706.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_013200820.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_013197984.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013185666.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_013191634.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_013187526.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013198107.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_013192756.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_013191432.1 7 MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3 "Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate" XP_013191719.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013191302.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_013199450.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013190583.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_013194918.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_013186591.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013186766.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_013196273.1 22 MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7592;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7036 "Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_013184960.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_013197550.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013188728.1 11 Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"Syndecan interactions";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type" XP_013191673.1 3 Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1" XP_013186450.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013194264.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_013200449.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013183993.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_013195169.1 6 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I" XP_013200793.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_013198312.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_013185821.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013186486.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013188845.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_013192616.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_013183326.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_013195999.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_013191097.1 11 Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-73779 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Ub-specific processing proteases";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_013182987.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_013199199.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_013193236.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_013195025.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_013188251.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes" XP_013184184.1 12 Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484 "Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)" XP_013190154.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040 "D-Alanine metabolism";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis" XP_013197648.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425 "Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"ABC-family proteins mediated transport";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Downstream TCR signaling";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Neddylation";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1" XP_013189090.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013183422.1 8 MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-4984;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-7400 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Canavanine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)" XP_013191791.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_013185810.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_013188404.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013193138.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207 "SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_013199459.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013187092.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_013186584.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_013194510.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_013195130.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_013197827.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833 "Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Cilium Assembly" XP_013183570.1 6 MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66 "3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system" XP_013200395.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres" XP_013184341.1 16 Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-1236974;Reactome: R-HSA-975110;Reactome: R-HSA-5602680;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-9020702;Reactome: R-HSA-1810476 "IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"ER-Phagosome pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR5)";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"Interleukin-1 signaling";"RIP-mediated NFkB activation via ZBP1" XP_013189274.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013199109.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_013196942.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_013183108.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013197822.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013196271.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1" XP_013186940.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_013190052.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013183931.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013189156.1 13 KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;MetaCyc: PWY-7039;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-2871809 "Phosphatidylinositol signaling system";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidate metabolism, as a signaling molecule";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"FCERI mediated Ca+2 mobilization" XP_013197153.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013188657.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013197179.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_013188261.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4 "Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_013200923.1 3 KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_013200420.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174178 "Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_013187878.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_013190079.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013187748.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_013196077.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013188229.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_013199695.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_013185342.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6807878 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport" XP_013184621.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292 "Neutrophil degranulation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome" XP_013191229.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_013189060.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013196225.1 7 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis" XP_013193729.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions" XP_013189182.1 13 Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1 "G alpha (12/13) signalling events";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"EPHB-mediated forward signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"G alpha (q) signalling events";"Relaxin signaling pathway" XP_013190063.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058 "ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling" XP_013193813.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453 "Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response" XP_013192839.1 7 MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_013195327.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-1268020 "Processing of SMDT1";"Mitochondrial protein import" XP_013198411.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013198635.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210 "Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_013183391.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_013199363.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013185139.1 14 Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290 "Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation" XP_013186295.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_013193246.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_013187370.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids" XP_013199052.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_013200753.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013189364.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_013194683.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_013196154.1 8 MetaCyc: PWY-241;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_013186449.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013188460.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_013184263.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_013196998.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" XP_013187013.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_013199683.1 16 Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519 "Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression" XP_013183310.1 12 MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-6936;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6309;MetaCyc: PWY-801;Reactome: R-HSA-71240 "Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Tryptophan catabolism" XP_013199858.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_013200773.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_013184630.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_013195672.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_013196708.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_013192173.1 15 Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569 "Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_013199178.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-113507 "CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_013191614.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3000178 "Protein ubiquitination";"ECM proteoglycans" XP_013200112.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_013193263.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013192000.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013194245.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_013190099.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_013193720.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_013182976.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013196038.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_013186609.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-6798695 "WNT ligand biogenesis and trafficking";"Neutrophil degranulation" XP_013199474.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013187208.1 3 Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45 "Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism" XP_013197716.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_013200681.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_013190822.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_013190204.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors" XP_013196285.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_013200956.1 8 MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183 "Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_013194489.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013189567.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013190081.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_013190586.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_013188576.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_013192606.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_013197613.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_013184929.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013197169.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_013185555.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_013188301.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638 "Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"snRNP Assembly";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins" XP_013190364.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_013186371.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013191080.1 6 MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941 "Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Glycogen degradation II" XP_013191178.1 40 Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167243 "RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"mRNA Capping";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery" XP_013191413.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_013196918.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_013188655.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_013183866.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013198705.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013183936.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_013200761.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_013188403.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_013190107.1 3 MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8 "L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation" XP_013191518.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_013193150.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_013193574.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation" XP_013193893.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013196037.1 4 KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_013201115.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_013183702.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013192005.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_013185909.1 8 Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_013201216.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781 "Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)" XP_013185650.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013189450.1 11 Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6549;Reactome: R-HSA-8964539 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism" XP_013190251.1 4 KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_013194620.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013186224.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_013191828.1 17 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_013185137.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_013185827.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_013194493.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013196690.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_013187827.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013192885.1 15 Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333 "Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated" XP_013190874.1 4 MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_013191593.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_013197066.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1 "Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes" XP_013197543.1 27 Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-5578749 "Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"snRNP Assembly";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs" XP_013200552.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013183810.1 11 Reactome: R-HSA-1660499;Reactome: R-HSA-168138;MetaCyc: PWY-6352;Reactome: R-HSA-109704;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137 "Synthesis of PIPs at the plasma membrane";"Toll Like Receptor 9 (TLR9) Cascade";"3-phosphoinositide biosynthesis";"PI3K Cascade";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system" XP_013186180.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_013196477.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_013199444.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013190552.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013190339.1 8 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013188593.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_013189975.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013194320.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_013188975.1 6 Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_013199611.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_013194523.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013183989.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013200652.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013199107.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013184483.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_013191683.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013188568.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_013191899.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_013197036.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_013194147.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013195118.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013183378.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_013187197.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013200401.1 11 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-204626;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Hypusine synthesis from eIF5A-lysine";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Ub-specific processing proteases";"mTOR signaling pathway" XP_013187164.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_013194905.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_013183736.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_013200430.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane" XP_013194827.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_013196331.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781 "HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression" XP_013201246.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_013184992.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_013190729.1 24 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-444257;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-114604;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400 "mTOR signaling pathway";"Human papillomavirus infection";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"RSK activation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"GPVI-mediated activation cascade";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"Activation of AKT2";"Human cytomegalovirus infection";"Estrogen-stimulated signaling through PRKCZ";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_013184174.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" XP_013197705.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation" XP_013193520.1 6 MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6722 "Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis" XP_013199557.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes" XP_013199633.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013186595.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013184923.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_013200461.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_013190738.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_013188008.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_013193773.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" XP_013190201.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_013194310.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_013193326.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_013196329.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_013188187.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013195909.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013197637.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_013200243.1 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-8004 "Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I" XP_013199714.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_013198700.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_013193142.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_013191103.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_013188651.1 20 MetaCyc: PWY-5136;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7340 "Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_013199778.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_013189507.1 3 KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_013189342.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_013191904.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013186571.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_013187346.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013190049.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_013191204.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_013184643.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402 "PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex" XP_013183469.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_013192518.1 2 Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Formation of apoptosome" XP_013187111.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_013197670.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy" XP_013200315.1 6 MetaCyc: PWY-6898;MetaCyc: PWY-7356;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;Reactome: R-HSA-196819 "Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism" XP_013199754.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_013185674.1 4 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_013183437.1 12 MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187 "Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine" XP_013187870.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013188399.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978 "Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Neddylation";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_013198024.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)" XP_013188186.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_013200110.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_013184896.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_013192442.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_013196631.1 3 MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450 "Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion" XP_013188984.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_013185215.1 2 Reactome: R-HSA-83936;Reactome: R-HSA-5619063 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)" XP_013183694.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_013190282.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-202424 "Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling" XP_013199869.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013191120.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013183318.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013188833.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_013186808.1 17 Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-3270619;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"IRF3-mediated induction of type I IFN";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_013188844.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_013200852.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_013199733.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_013188697.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_013187561.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_013197496.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_013194466.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_013195398.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_013200415.1 7 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex" XP_013184600.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_013183863.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013200235.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR" XP_013184395.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013194173.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_013190758.1 13 KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-6370;Reactome: R-HSA-196836;MetaCyc: PWY-7533 "Glutathione metabolism";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis" XP_013187372.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_013185695.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production" XP_013185357.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_013189387.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013185569.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_013197168.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_013183772.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" XP_013185099.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_013185816.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_013194272.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-69481 "ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints" XP_013192180.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_013189971.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_013196336.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_013197043.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_013183677.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257 "Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Neddylation";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN" XP_013197458.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013186895.1 4 KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_013186737.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013195049.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_013197031.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_013188458.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_013190533.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_013185703.1 6 MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906 "D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_013185335.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013184810.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_013193155.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_013199738.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_013190309.1 7 Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2 "Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Cristae formation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Oxidative phosphorylation" XP_013193632.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_013192289.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_013189633.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_013185464.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_013185918.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_013198205.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_013192532.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608 "Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation" XP_013198697.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_013189365.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_013185920.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_013195885.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_013183540.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_013193887.1 9 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway" XP_013189708.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_013190750.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_013192614.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_013192841.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_013186328.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_013189386.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_013196642.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_013197238.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_013191789.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_013188117.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_013189467.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_013183186.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_013199253.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_013190808.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_013190310.1 7 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_013192464.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_013198418.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_013190787.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_013196919.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_013188999.1 11 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation" XP_013191448.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_013192706.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_013184309.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_013197606.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751 "Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity" XP_013193525.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_013190363.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_013193202.1 20 Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169 "PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Polymerase switching";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis" XP_013198449.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_013184241.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_013191600.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-202424 "Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Neddylation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"UCH proteinases";"ABC-family proteins mediated transport";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Downstream TCR signaling" XP_013195841.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_013200647.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499 "Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane" XP_013186863.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_013198108.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_013194903.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_013191549.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_013189751.1 20 KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1 "mTOR si